LOCUS       DBERXF010000001       115769 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.01, whole genome shotgun sequence.
ACCESSION   DBERXF010000001 DBERXF010000000
VERSION     DBERXF010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 115769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 115769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..115769
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.01"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..228
                     /locus_tag="ACL8JK_000001"
     CDS             <1..228
                     /locus_tag="ACL8JK_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGS1784968.1"
                     /translation="SASTSASASASTSVSNSANHSNSQVGNTSGSTGKSQKELPNTGT
                     ESSIGSVLLGVLAAVTGIGLVAKRRKRDEEE"
     gene            289..2373
                     /locus_tag="ACL8JK_000002"
     CDS             289..2373
                     /locus_tag="ACL8JK_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS1784969.1"
                     /translation="MDDKITVIVPVYNVENYLRKCLDSIISQTYKNIEIVVVNDGSTD
                     ASGEICKEFSEMDHRILYIEQENAGLSAARNTGLNNMSGNYVTFVDSDDWIEQDYVET
                     LYKKIVEYQADIAVGNYYSFNESEGMFYFHISGDYYYEKVYDNVSIFENLYETQEMKS
                     FALISACGKLYKARLFEQLRFDMGKLVEDGYLNQKVYLLSEKVIYLNKGLYAYRIRKG
                     SLSRVWTEKWMHALVDAMSERITLLANMGYPLEKHLAVYRQMLEVSLANGQASGLSDT
                     AIYKEFEMKKRLLNQLTVQESSEKKAIVLAANYGYVDQVLTTIKSICYHNRSIRFYLI
                     HSDFPNEWIKQLNKRLEKFDSEIINCRVTSEQISCYKTDISYTVFLRYFIADFVQEDK
                     ALYLDCDLLVTKNLDDLFATDLQDYPLAAVRDFGGRAYFGQEIFNAGVLLVNNAFWKK
                     ENMTQKLIDVTNEWHDKVDQADQSILNMLFEHKWLELDFDYNHIVIHKQFADYQLPEG
                     QDYPAIIHYLSHRKPWKDLAAQTYREVWWYYHGLEWTELGQNHHLHPLQRSHIYPIKE
                     PFTCLIYTASDHIEQIETLVQSLPDIQFKIAARVIVSDRLAQMTIYPNVTIFNGIHYL
                     VDVDNELVETSQVLLDINHGEKTEEIINQFARLGKTILSFENTKTYEAGQEVYAVDQV
                     QAMIEKLREISK"
     gene            2680..3894
                     /locus_tag="ACL8JK_000003"
     CDS             2680..3894
                     /locus_tag="ACL8JK_000003"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HGS1784970.1"
                     /translation="MNTKSIVFNADNDYVDKLETAIKSICCYNNCLKFYVFNDDIASE
                     WFLMMNKRLKTIQSEIVNVKIVDHVLKKFHLPLKNLSYATFFRYFIPNFVKESRALYL
                     DSDIIVTGSLDYLFDIELDGYALAAVEDSFGDVPSTNFNSGMLLVNVDTWRDEDACSK
                     LLELTNQYHETAYGDQGILNMLFHDRWKRLDRNFNFMVGMDSVAHIEGNHKWYEISEL
                     KNGDLPSVIHYTGVKPWEIISNNRFREVWWFYNLLEWSDILLRKDIISRSFEELVYSP
                     KAHTAIFTASCEMEHVEYLIENLPEVHFSILAHTYFASSVVALLRYSNVTIYPCFSPF
                     DYRKILDNLDFYLDINHYKEVDNIVSVVQQLSKPIFTFENTSHDIGNQTNIFSSTEPN
                     KMVEAIRQFIGE"
     gene            3899..4774
                     /locus_tag="ACL8JK_000004"
     CDS             3899..4774
                     /locus_tag="ACL8JK_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1784971.1"
                     /translation="MADELISIVVPIYNVENYLRMCLDSIQNQTYQNFECLLINDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGAYITFVDSDDWLEHDALD
                     RLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDDSLEVIEGKAIMDREGVEEVRN
                     GNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVLLRASRIVYLNRCVYWYRVGLS
                     DTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHILIYKNRLQRVIAKLEEQNMQF
                     TEIYRRMMEKLSLLP"
     gene            4803..5813
                     /locus_tag="ACL8JK_000005"
     CDS             4803..5813
                     /locus_tag="ACL8JK_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGS1784972.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSSARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTHQNEGESNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAEFIV
                     DQGLGFVANSLEEVHEIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLFVDAIYHLG
                     VE"
     gene            5823..8267
                     /locus_tag="ACL8JK_000006"
     CDS             5823..8267
                     /locus_tag="ACL8JK_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HGS1784973.1"
                     /translation="MIKTIVLAGDRNYIRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYARYFIADYIQEDKVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNAGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELGRAYNLQVGHDVVALYNNWQEHLAF
                     NDKPAVIHFTTYRKPWTTLIANRYRDLWWEFHDLEWNQILQHHIGEFEMTSPLDKEFS
                     CLTLTNSQDLEGIEELVTALPEVVFHIAAWTDMGDKLKKLAVYNNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQDIEQLDYLAGQLPNVVFQVAAWTAMGPKL
                     YDLSNRYPNIQLYPAISRDKLDELKEKMDAYLDINLLTSTSDIVAEMAHLSKPILAFY
                     KSQNGNNGQRLYSSEHPERMLADLQKLITKDMLEKPLDIIQVKGIDETLDYIIEHNSS
                     LVRFGDGEVNLMWGLPIPYQNHDLELANQLKHIVGFESDEKLVVCLPDAFDDRFVFTW
                     WATPFWKEHMNVYMDFYKELCKGSWYGSTFISRPYIDYEDKSKAKGQFEKLKSIWENR
                     DILIVEGITSRSGVGNDLFDKVKSVKRIICPSHNAYSVVDNIQEEIMKHAEGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHVDSEYEWMKMGAKTKVKFSHKHTAEHNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            8298..9518
                     /locus_tag="ACL8JK_000007"
     CDS             8298..9518
                     /locus_tag="ACL8JK_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS1784974.1"
                     /translation="MRNTKRAVVFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            9527..10723
                     /locus_tag="ACL8JK_000008"
     CDS             9527..10723
                     /locus_tag="ACL8JK_000008"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HGS1784975.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKTEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFVTEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNAGMLLMDVVKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNLPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMFVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELISLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            10723..11625
                     /locus_tag="ACL8JK_000009"
     CDS             10723..11625
                     /locus_tag="ACL8JK_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001292324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1784976.1"
                     /translation="MSELISVVVPIYNTGKYLVGCVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGAAQAKNMGISVAKGEYITIVDSDDIVKENMIET
                     LYQQVQEKDADVVIGNYYNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFNS
                     SAFILPTFKLIKKELFNEVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRSG
                     SIMRTEFDLSWARDIVEVFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLTD
                     TEEYKDICFRLKLFFDAEQRNGKS"
     gene            11682..12899
                     /gene="secY2"
                     /locus_tag="ACL8JK_000010"
     CDS             11682..12899
                     /gene="secY2"
                     /locus_tag="ACL8JK_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HGS1784977.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     KMYLTLMIAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYSYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMIGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYRPLI"
     gene            12909..14489
                     /gene="asp1"
                     /locus_tag="ACL8JK_000011"
     CDS             12909..14489
                     /gene="asp1"
                     /locus_tag="ACL8JK_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HGS1784978.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFGPNGQIHMHYIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLADVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            14473..16008
                     /gene="asp2"
                     /locus_tag="ACL8JK_000012"
     CDS             14473..16008
                     /gene="asp2"
                     /locus_tag="ACL8JK_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HGS1784979.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKALREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            16005..16445
                     /gene="asp3"
                     /locus_tag="ACL8JK_000013"
     CDS             16005..16445
                     /gene="asp3"
                     /locus_tag="ACL8JK_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HGS1784980.1"
                     /translation="MIITQRQSIYWGEVGGTYMYGTTVSYYPDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            16438..18810
                     /gene="secA2"
                     /locus_tag="ACL8JK_000014"
     CDS             16438..18810
                     /gene="secA2"
                     /locus_tag="ACL8JK_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HGS1784981.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            18822..20333
                     /gene="gtfA"
                     /locus_tag="ACL8JK_000015"
     CDS             18822..20333
                     /gene="gtfA"
                     /locus_tag="ACL8JK_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HGS1784982.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLRDIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            20326..21663
                     /gene="gtfB"
                     /locus_tag="ACL8JK_000016"
     CDS             20326..21663
                     /gene="gtfB"
                     /locus_tag="ACL8JK_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031647 - regulation of protein stability
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HGS1784983.1"
                     /translation="MIELYDRYSHESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYADGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGTCFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHYPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKTTYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIVEALPDVTFRIAAVTEMSSKLLDMLCYPNVALY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYVAPDH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQETMQTVLGG"
     gene            21665..21844
                     /gene="asp4"
                     /locus_tag="ACL8JK_000017"
     CDS             21665..21844
                     /gene="asp4"
                     /locus_tag="ACL8JK_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HGS1784984.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            21849..22073
                     /locus_tag="ACL8JK_000018"
     CDS             21849..22073
                     /locus_tag="ACL8JK_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HGS1784985.1"
                     /translation="MIDILIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            22134..22286
                     /locus_tag="ACL8JK_000019"
     CDS             22134..22286
                     /locus_tag="ACL8JK_000019"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1784986.1"
                     /translation="MKIKEQTRKLAAGCSKHGFEVVDRTDEVSSKHGFEVVDRTDEVS
                     NIYTAR"
     gene            complement(22309..23262)
                     /locus_tag="ACL8JK_000020"
     CDS             complement(22309..23262)
                     /locus_tag="ACL8JK_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGS1784987.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(23330..24539)
                     /gene="sstT"
                     /locus_tag="ACL8JK_000021"
                     /pseudo
     CDS             complement(23330..24539)
                     /gene="sstT"
                     /locus_tag="ACL8JK_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            24678..25238
                     /locus_tag="ACL8JK_000022"
     CDS             24678..25238
                     /locus_tag="ACL8JK_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HGS1784988.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            25295..26203
                     /locus_tag="ACL8JK_000023"
     CDS             25295..26203
                     /locus_tag="ACL8JK_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGS1784989.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            26218..26745
                     /locus_tag="ACL8JK_000024"
     CDS             26218..26745
                     /locus_tag="ACL8JK_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGS1784990.1"
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNN
                     PDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRA
                     MKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMR
                     KITEKYGPITYKKGI"
     gene            26748..27854
                     /gene="yqeH"
                     /locus_tag="ACL8JK_000025"
     CDS             26748..27854
                     /gene="yqeH"
                     /locus_tag="ACL8JK_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGS1784991.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            28069..28380
                     /gene="yhbY"
                     /locus_tag="ACL8JK_000026"
     CDS             28069..28380
                     /gene="yhbY"
                     /locus_tag="ACL8JK_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGS1784992.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            28432..29061
                     /locus_tag="ACL8JK_000027"
     CDS             28432..29061
                     /locus_tag="ACL8JK_000027"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGS1784993.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRAFLAQGRKPNFLLPQLVLDYIEKEGLY"
     gene            29061..29654
                     /gene="yqeK"
                     /locus_tag="ACL8JK_000028"
     CDS             29061..29654
                     /gene="yqeK"
                     /locus_tag="ACL8JK_000028"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGS1784994.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVVYVADYIEHNRSFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            29655..30155
                     /locus_tag="ACL8JK_000029"
     CDS             29655..30155
                     /locus_tag="ACL8JK_000029"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGS1784995.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEGWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            30168..30521
                     /gene="rsfS"
                     /locus_tag="ACL8JK_000030"
     CDS             30168..30521
                     /gene="rsfS"
                     /locus_tag="ACL8JK_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGS1784996.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            30630..31370
                     /locus_tag="ACL8JK_000031"
     CDS             30630..31370
                     /locus_tag="ACL8JK_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS1784997.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNVLNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            31380..32477
                     /locus_tag="ACL8JK_000032"
     CDS             31380..32477
                     /locus_tag="ACL8JK_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGS1784998.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGTEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARESDLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAQQNFGRVPIRIETN"
     gene            32715..32969
                     /locus_tag="ACL8JK_000033"
     CDS             32715..32969
                     /locus_tag="ACL8JK_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGS1784999.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            32973..33227
                     /locus_tag="ACL8JK_000034"
     CDS             32973..33227
                     /locus_tag="ACL8JK_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HGS1785000.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            33418..35031
                     /locus_tag="ACL8JK_000035"
     CDS             33418..35031
                     /locus_tag="ACL8JK_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGS1785001.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            35161..35787
                     /gene="gmk"
                     /locus_tag="ACL8JK_000036"
     CDS             35161..35787
                     /gene="gmk"
                     /locus_tag="ACL8JK_000036"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGS1785002.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            35812..36126
                     /gene="rpoZ"
                     /locus_tag="ACL8JK_000037"
     CDS             35812..36126
                     /gene="rpoZ"
                     /locus_tag="ACL8JK_000037"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGS1785003.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            36192..38588
                     /locus_tag="ACL8JK_000038"
     CDS             36192..38588
                     /locus_tag="ACL8JK_000038"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGS1785004.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVFGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVRRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            38601..39536
                     /gene="fmt"
                     /locus_tag="ACL8JK_000039"
     CDS             38601..39536
                     /gene="fmt"
                     /locus_tag="ACL8JK_000039"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGS1785005.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDNRYEILAVATQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSICKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            39529..40842
                     /gene="rsmB"
                     /locus_tag="ACL8JK_000040"
     CDS             39529..40842
                     /gene="rsmB"
                     /locus_tag="ACL8JK_000040"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGS1785006.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGIEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            40857..41597
                     /locus_tag="ACL8JK_000041"
     CDS             40857..41597
                     /locus_tag="ACL8JK_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGS1785007.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            41594..43573
                     /gene="stkP"
                     /locus_tag="ACL8JK_000042"
     CDS             41594..43573
                     /gene="stkP"
                     /locus_tag="ACL8JK_000042"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="HGS1785008.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            43688..44446
                     /locus_tag="ACL8JK_000043"
     CDS             43688..44446
                     /locus_tag="ACL8JK_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGS1785009.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            44448..44897
                     /locus_tag="ACL8JK_000044"
     CDS             44448..44897
                     /locus_tag="ACL8JK_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGS1785010.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            44959..45585
                     /locus_tag="ACL8JK_000045"
                     /pseudo
     CDS             44959..45585
                     /locus_tag="ACL8JK_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            45653..45901
                     /locus_tag="ACL8JK_000046"
     CDS             45653..45901
                     /locus_tag="ACL8JK_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785011.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            46032..47204
                     /locus_tag="ACL8JK_000047"
     CDS             46032..47204
                     /locus_tag="ACL8JK_000047"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGS1785012.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            47204..48478
                     /locus_tag="ACL8JK_000048"
     CDS             47204..48478
                     /locus_tag="ACL8JK_000048"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGS1785013.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNDQEYTVPYVTEEPSVVAAASYAIKIIKRTGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(48513..49478)
                     /locus_tag="ACL8JK_000049"
     CDS             complement(48513..49478)
                     /locus_tag="ACL8JK_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1785014.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(49459..50913)
                     /locus_tag="ACL8JK_000050"
     CDS             complement(49459..50913)
                     /locus_tag="ACL8JK_000050"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HGS1785015.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            51290..53173
                     /locus_tag="ACL8JK_000051"
     CDS             51290..53173
                     /locus_tag="ACL8JK_000051"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGS1785016.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSIPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            53320..54207
                     /gene="scrK"
                     /locus_tag="ACL8JK_000052"
     CDS             53320..54207
                     /gene="scrK"
                     /locus_tag="ACL8JK_000052"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGS1785017.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(54527..55144)
                     /locus_tag="ACL8JK_000053"
     CDS             complement(54527..55144)
                     /locus_tag="ACL8JK_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HGS1785018.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(55559..55772)
                     /locus_tag="ACL8JK_000054"
                     /pseudo
     CDS             complement(55559..55772)
                     /locus_tag="ACL8JK_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(56140..56331)
                     /locus_tag="ACL8JK_000055"
     CDS             complement(56140..56331)
                     /locus_tag="ACL8JK_000055"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785019.1"
                     /translation="MKIKEQTRKLAVDCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYIYGKAKLTWFEEIFEEY"
     gene            56454..57347
                     /locus_tag="ACL8JK_000056"
     CDS             56454..57347
                     /locus_tag="ACL8JK_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785020.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLADKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            57344..58543
                     /locus_tag="ACL8JK_000057"
     CDS             57344..58543
                     /locus_tag="ACL8JK_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1785021.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILVHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(58896..59663)
                     /locus_tag="ACL8JK_000058"
     CDS             complement(58896..59663)
                     /locus_tag="ACL8JK_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785022.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(59680..60375)
                     /locus_tag="ACL8JK_000059"
     CDS             complement(59680..60375)
                     /locus_tag="ACL8JK_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785023.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(60380..60745)
                     /locus_tag="ACL8JK_000060"
     CDS             complement(60380..60745)
                     /locus_tag="ACL8JK_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS1785024.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            60885..61358
                     /gene="nrdR"
                     /locus_tag="ACL8JK_000061"
     CDS             60885..61358
                     /gene="nrdR"
                     /locus_tag="ACL8JK_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGS1785025.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            61359..62528
                     /locus_tag="ACL8JK_000062"
     CDS             61359..62528
                     /locus_tag="ACL8JK_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGS1785026.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLVLHAPLSSQD
                     FLEHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKIQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            62529..63425
                     /gene="dnaI"
                     /locus_tag="ACL8JK_000063"
     CDS             62529..63425
                     /gene="dnaI"
                     /locus_tag="ACL8JK_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGS1785027.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            63422..64135
                     /locus_tag="ACL8JK_000064"
     CDS             63422..64135
                     /locus_tag="ACL8JK_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HGS1785028.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYPVFGMAL
                     GVPNQTHDVKPRLPLDNVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            64149..65459
                     /gene="der"
                     /locus_tag="ACL8JK_000065"
     CDS             64149..65459
                     /gene="der"
                     /locus_tag="ACL8JK_000065"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGS1785029.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            65548..65883
                     /locus_tag="ACL8JK_000066"
     CDS             65548..65883
                     /locus_tag="ACL8JK_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785030.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            66023..66358
                     /locus_tag="ACL8JK_000067"
     CDS             66023..66358
                     /locus_tag="ACL8JK_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785031.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            66543..67334
                     /locus_tag="ACL8JK_000068"
     CDS             66543..67334
                     /locus_tag="ACL8JK_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785032.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAILTHFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAVYFLQIVDYLGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVSYMVLEKYEDNV"
     gene            67327..67968
                     /locus_tag="ACL8JK_000069"
     CDS             67327..67968
                     /locus_tag="ACL8JK_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785033.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEVNLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            67972..68604
                     /locus_tag="ACL8JK_000070"
     CDS             67972..68604
                     /locus_tag="ACL8JK_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1785034.1"
                     /translation="MRLEIINGQKIYRKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDIEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            68632..68919
                     /locus_tag="ACL8JK_000071"
     CDS             68632..68919
                     /locus_tag="ACL8JK_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785035.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDKPLLGIRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITLAILPIFGN"
     gene            69065..71578
                     /gene="secA"
                     /locus_tag="ACL8JK_000072"
     CDS             69065..71578
                     /gene="secA"
                     /locus_tag="ACL8JK_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGS1785036.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMTALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            71659..72690
                     /locus_tag="ACL8JK_000073"
     CDS             71659..72690
                     /locus_tag="ACL8JK_000073"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGS1785037.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            72692..73723
                     /locus_tag="ACL8JK_000074"
     CDS             72692..73723
                     /locus_tag="ACL8JK_000074"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGS1785038.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            73768..74130
                     /gene="acpS"
                     /locus_tag="ACL8JK_000075"
     CDS             73768..74130
                     /gene="acpS"
                     /locus_tag="ACL8JK_000075"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGS1785039.1"
                     /translation="MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGR
                     RQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSIS
                     HTDQFVTASVILEENHES"
     gene            74120..75223
                     /gene="alr"
                     /locus_tag="ACL8JK_000076"
     CDS             74120..75223
                     /gene="alr"
                     /locus_tag="ACL8JK_000076"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGS1785040.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPSGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            75242..77257
                     /gene="recG"
                     /locus_tag="ACL8JK_000077"
     CDS             75242..77257
                     /gene="recG"
                     /locus_tag="ACL8JK_000077"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGS1785041.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRIQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTAHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            77573..78553
                     /locus_tag="ACL8JK_000078"
     CDS             77573..78553
                     /locus_tag="ACL8JK_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HGS1785042.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            79403..79630
                     /locus_tag="ACL8JK_000079"
     CDS             79403..79630
                     /locus_tag="ACL8JK_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785043.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            79918..82815
                     /gene="nanA"
                     /locus_tag="ACL8JK_000080"
     CDS             79918..82815
                     /gene="nanA"
                     /locus_tag="ACL8JK_000080"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HGS1785044.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNNQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            83828..84280
                     /locus_tag="ACL8JK_000081"
     CDS             83828..84280
                     /locus_tag="ACL8JK_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGS1785045.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGDFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            84299..85636
                     /locus_tag="ACL8JK_000082"
     CDS             84299..85636
                     /locus_tag="ACL8JK_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1785046.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            85715..86599
                     /locus_tag="ACL8JK_000083"
     CDS             85715..86599
                     /locus_tag="ACL8JK_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1785047.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            86599..87432
                     /locus_tag="ACL8JK_000084"
     CDS             86599..87432
                     /locus_tag="ACL8JK_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1785048.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            87627..88730
                     /locus_tag="ACL8JK_000085"
     CDS             87627..88730
                     /locus_tag="ACL8JK_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGS1785049.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            88904..89602
                     /locus_tag="ACL8JK_000086"
     CDS             88904..89602
                     /locus_tag="ACL8JK_000086"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGS1785050.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            89621..91138
                     /locus_tag="ACL8JK_000087"
     CDS             89621..91138
                     /locus_tag="ACL8JK_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGS1785051.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            91263..92591
                     /locus_tag="ACL8JK_000088"
     CDS             91263..92591
                     /locus_tag="ACL8JK_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1785052.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            92843..93709
                     /locus_tag="ACL8JK_000089"
     CDS             92843..93709
                     /locus_tag="ACL8JK_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1785053.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            93725..94564
                     /locus_tag="ACL8JK_000090"
     CDS             93725..94564
                     /locus_tag="ACL8JK_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1785054.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            94836..95288
                     /locus_tag="ACL8JK_000091"
     CDS             94836..95288
                     /locus_tag="ACL8JK_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGS1785055.1"
                     /translation="MIFDDLKNITFYKGIYPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCYEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            95385..95729
                     /locus_tag="ACL8JK_000092"
     CDS             95385..95729
                     /locus_tag="ACL8JK_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785056.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVNALIGRYIKLGAY
                     AAKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            95739..95933
                     /locus_tag="ACL8JK_000093"
     CDS             95739..95933
                     /locus_tag="ACL8JK_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785057.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFNEHTWSTILIASLSGI
                     YIDYMSIDKSRKKSKRKKKK"
     gene            96016..96660
                     /locus_tag="ACL8JK_000094"
     CDS             96016..96660
                     /locus_tag="ACL8JK_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGS1785058.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            96829..97746
                     /locus_tag="ACL8JK_000095"
     CDS             96829..97746
                     /locus_tag="ACL8JK_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HGS1785059.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTATHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            97764..98648
                     /locus_tag="ACL8JK_000096"
     CDS             97764..98648
                     /locus_tag="ACL8JK_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGS1785060.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(98664..99515)
                     /locus_tag="ACL8JK_000097"
     CDS             complement(98664..99515)
                     /locus_tag="ACL8JK_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGS1785061.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQTSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            99715..101772
                     /gene="pbp2b"
                     /locus_tag="ACL8JK_000098"
     CDS             99715..101772
                     /gene="pbp2b"
                     /locus_tag="ACL8JK_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HGS1785062.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLGSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEINKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            101783..102379
                     /gene="recR"
                     /locus_tag="ACL8JK_000099"
     CDS             101783..102379
                     /gene="recR"
                     /locus_tag="ACL8JK_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGS1785063.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDSTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            102555..103598
                     /locus_tag="ACL8JK_000100"
     CDS             102555..103598
                     /locus_tag="ACL8JK_000100"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGS1785064.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDSIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWENMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            103682..105055
                     /gene="murF"
                     /locus_tag="ACL8JK_000101"
     CDS             103682..105055
                     /gene="murF"
                     /locus_tag="ACL8JK_000101"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGS1785065.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENECK"
     gene            105042..105653
                     /locus_tag="ACL8JK_000102"
     CDS             105042..105653
                     /locus_tag="ACL8JK_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HGS1785066.1"
                     /translation="MNASDFAKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDADEVAELLKPTSAYATPLMDVRAWIVEDEKICLVRGQGENDWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            105744..106448
                     /locus_tag="ACL8JK_000103"
     CDS             105744..106448
                     /locus_tag="ACL8JK_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HGS1785067.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYRENK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            106667..108040
                     /gene="ftsA"
                     /locus_tag="ACL8JK_000104"
     CDS             106667..108040
                     /gene="ftsA"
                     /locus_tag="ACL8JK_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGS1785068.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKEAFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVELVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            108057..109316
                     /gene="ftsZ"
                     /locus_tag="ACL8JK_000105"
     CDS             108057..109316
                     /gene="ftsZ"
                     /locus_tag="ACL8JK_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGS1785069.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            109321..109992
                     /locus_tag="ACL8JK_000106"
     CDS             109321..109992
                     /locus_tag="ACL8JK_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGS1785070.1"
                     /translation="MNVKENTELVFREVAEASLSANRERGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            110002..110541
                     /locus_tag="ACL8JK_000107"
     CDS             110002..110541
                     /locus_tag="ACL8JK_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGS1785071.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            110541..110804
                     /locus_tag="ACL8JK_000108"
     CDS             110541..110804
                     /locus_tag="ACL8JK_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGS1785072.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            110801..111586
                     /locus_tag="ACL8JK_000109"
     CDS             110801..111586
                     /locus_tag="ACL8JK_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGS1785073.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            111595..112383
                     /gene="divIVA"
                     /locus_tag="ACL8JK_000110"
     CDS             111595..112383
                     /gene="divIVA"
                     /locus_tag="ACL8JK_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HGS1785074.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLVQLAQCMKNQK"
     gene            112731..115523
                     /gene="ileS"
                     /locus_tag="ACL8JK_000111"
     CDS             112731..115523
                     /gene="ileS"
                     /locus_tag="ACL8JK_000111"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGS1785075.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNSPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGETRKFVVAAELLTSLSEK
                     FGWVDVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDKLRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQVVICDHCASI
                     VEENFVEAVAEGFEEK"
BASE COUNT        35178 a        20735 c        25674 g        34182 t
ORIGIN      
        1 tcagcaagta ccagtgcgtc agcttcagca agtacatcag tttcaaattc agcaaaccat
       61 tcgaactcac aagttggaaa tacttctgga tcgacaggta aatcccaaaa agaattgcct
      121 aatacaggta ctgagtcgtc aattggatct gtgttacttg gagttctagc agctgttaca
      181 ggtattggat tggttgcgaa acgccgtaaa cgtgatgaag aagagtaaga caacctgtaa
      241 agttaggcta aactaactcg cgcacataaa tcaaggagaa aattgctagt ggatgataaa
      301 attacggtca ttgtaccagt atacaatgta gaaaactatc tgaggaaatg tctagatagt
      361 attatttctc aaacatataa aaatattgag attgttgtcg ttaatgatgg ttctacggat
      421 gcttcaggtg aaatttgtaa agaattttca gaaatggatc accgaattct ctatatagaa
      481 caagaaaatg ctggtctttc tgccgcacga aacaccggtc tgaataatat gtccggaaat
      541 tatgtgacct ttgtggactc ggatgattgg attgagcaag attatgtaga aactctatat
      601 aaaaaaatag tagagtatca ggctgatatt gcagttggga attactattc tttcaacgaa
      661 agtgaaggaa tgttctactt tcatatatca ggagactact attatgagaa ggtatatgac
      721 aatgtttcca tctttgagaa cttgtatgaa actcaagaaa tgaagagttt tgctttgata
      781 tctgcttgtg gtaaactcta taaggcaaga ttgtttgagc agttgcgctt tgacatgggt
      841 aaattagtag aagatggtta cctcaatcaa aaggtatatt tattatcgga aaaggtaatt
      901 tatttaaata aaggtcttta tgcttatcgg attagaaaag gtagtctatc aagagtttgg
      961 acagaaaagt ggatgcacgc cttagttgat gctatgtctg aacgtattac gctactagct
     1021 aatatgggat atcctctaga gaaacacttg gcagtttatc gtcagatgtt ggaagtcagt
     1081 ctcgccaacg gtcaagctag tggtttatct gacacagcaa tatataaaga gtttgaaatg
     1141 aaaaaaagac ttttaaatca gttaacggta caagaatcaa gtgaaaagaa agccattgtc
     1201 ctagcagcaa actatggcta tgtagaccaa gttttaacga caatcaagtc tatttgttat
     1261 cataatcgtt cgattcgttt ttatctgatt catagcgatt ttccaaatga atggattaag
     1321 caattaaata agcgcttaga gaagtttgac tcagaaatta ttaattgtcg ggtaacttct
     1381 gagcaaattt catgttataa aacggatatt agttacacag tttttttacg ctatttcata
     1441 gctgatttcg tgcaagaaga taaggccctc tacttggact gtgatttact tgtaacgaaa
     1501 aatcttgatg atttgtttgc tacagactta caagattatc ctttggctgc tgttagagat
     1561 tttgggggca gagcttattt tggtcaagaa atctttaatg ccggtgttct cttggtaaac
     1621 aatgcttttt ggaaaaaaga gaatatgacc caaaaattaa ttgatgtaac caatgaatgg
     1681 catgataagg tggatcaggc agatcagagc atcttgaata tgctttttga acataaatgg
     1741 ttggaattgg actttgatta taatcatatt gtcattcata aacagtttgc tgattatcaa
     1801 ttgcctgagg gtcaggatta tcctgctatt attcactatc tttctcatcg gaaaccgtgg
     1861 aaagatttgg cggcccaaac ctatcgtgaa gtttggtggt actatcatgg gcttgaatgg
     1921 acagaattgg gacaaaacca tcatttacat ccattacaaa gatctcacat ctatccaata
     1981 aaggaacctt tcacttgtct aatctatact gcctcagacc atattgaaca aattgagaca
     2041 ttggttcaat ccttgcctga tattcagttt aagatagcag ctagagtaat agttagtgat
     2101 cgattggctc agatgacaat ttatccaaac gtgactatat ttaacggaat tcactatttg
     2161 gtagatgtcg ataatgaatt ggtagaaacc agtcaagtac ttttagatat taatcatggt
     2221 gaaaaaacag aggaaattat caatcaattt gcaagacttg gaaaaactat tttgtccttt
     2281 gaaaatacca aaacctatga agcaggtcag gaggtatatg ctgttgacca agttcaagca
     2341 atgattgaga aattgagaga aataagcaaa tgaagaaaaa tcatttagta ggagatgctc
     2401 tgattttgac ggttagtgat cagattgaag agttggatta ttttttataa aatttctccg
     2461 ttcatcatat atgaaagttg ttcaaacatc agagtgcttt ataaaatata aatagaccta
     2521 aagatattta atatgaactg caccccaaaa gttagacaga aaaaatctaa ctttttgggg
     2581 tcagtacaat attagggtgt gattaattat ctttttaggt gaaaatgatt ctatattata
     2641 gctgtttgat acgaaattta ttataaggaa attatgttaa tgaatacaaa atctatagtt
     2701 tttaatgcag ataatgatta tgtagataaa ttagaaactg caattaaatc tatttgttgt
     2761 tataataatt gtttaaaatt ttatgtattt aatgatgata ttgcgtcaga gtggtttttg
     2821 atgatgaata agcgattgaa gactatacaa tctgaaatcg ttaatgtaaa gattgtagat
     2881 catgttctta aaaagtttca tttaccgtta aagaatttaa gttatgccac tttctttcgt
     2941 tattttatac ctaattttgt caaagaaagt cgtgctttat acctagattc tgacatcatt
     3001 gttacaggaa gtttagacta tttatttgat atagaactag atggttatgc cttggcagca
     3061 gtagaagatt cttttggtga tgttccttct accaatttta actccggaat gttattagtt
     3121 aatgtagata cttggagaga tgaagatgct tgttcgaaac tgttagaact gaccaatcaa
     3181 tatcatgaaa cagcatatgg agatcaagga attttaaata tgttattcca tgatagatgg
     3241 aaaagattag accgaaattt taattttatg gtggggatgg atagcgtcgc acacatagaa
     3301 ggaaatcata aatggtatga gatttctgag ttgaaaaatg gagatttacc tagtgttata
     3361 cattatactg gggtaaaacc ttgggaaata atttccaata atcgctttag agaagtttgg
     3421 tggttttata atctgttaga atggtctgat attttattga gaaaagacat tattagtcgt
     3481 agtttcgaag aacttgtata cagtcctaaa gctcatacag caatttttac agctagttgt
     3541 gagatggagc atgtagaata tttgatagaa aatttaccag aggtacattt ttctatacta
     3601 gcacatacat attttgcgtc tagtgtcgtt gctttattaa gatatagcaa tgttacgatt
     3661 tatccttgtt tttctccatt tgattatcga aaaattttgg ataatttaga tttttattta
     3721 gatattaatc attataaaga agtggataat attgtatccg ttgttcaaca actatctaaa
     3781 ccaattttta cctttgaaaa tactagtcat gatataggca atcaaactaa tatattttct
     3841 tcaaccgaac caaacaaaat ggtagaggct attagacaat ttataggaga ataagtttat
     3901 ggcagacgaa ctaattagta ttgtagttcc aatctacaat gttgagaatt atttgcgaat
     3961 gtgtttggat agcattcaga atcagacgta tcaaaatttt gagtgtttat taatcaatga
     4021 tggctctcca gatcattcat ccaaaatatg tgaagaattt gtagagaaag attctcgttt
     4081 caaatatttt gagaaagcaa acggcggtct ttcatcagct cgtaacctag gtattgaatg
     4141 ttcggggggg gcgtacatta cttttgtaga ctctgatgat tggttggaac atgatgcttt
     4201 agaccgatta tatggtgctt tgaaaaagga aaacgcagat attagtatcg ggcgttataa
     4261 ttcttatgat gaaacacgct atgtgtatat gacttatgtt acggatccag atgattctct
     4321 ggaagtgata gaaggtaaag caatcatgga tagggaaggt gtcgaagaag tcagaaatgg
     4381 gaactggact gtagctgtct tgaagttatt caagagagag ttactacaag atttaccatt
     4441 tcctatagga aaaattgcag aggatactta ctggacatgg aaggtacttc taagagcttc
     4501 gaggatagtc tatttgaatc gttgtgttta ctggtaccgt gttggtttat ctgatacttt
     4561 atcgaataca tggagtgaaa agcgtatgta tgatgaaatt ggggctaggg aagaaaagat
     4621 agctatttta gcaagttcag actatgactt gaccaatcat attttgattt ataaaaatag
     4681 attacaaaga gtgatagcaa aattagaaga acaaaatatg cagttcacag agatttatag
     4741 aagaatgatg gaaaaattgt ctttacttcc gtagatagta ataaaaaatg agatagcgta
     4801 atatgaaatt acatttaaca aatttatacg gcatggctgg tgatagtacg gttatcttag
     4861 ctcaaaatgc tgttcaaaag atagctagtc aactgggatt tagagaggtt ggtatttatt
     4921 tttacaacat tgcttcagat agtccttctg aaatgaataa gcgtctggat ggtattatgg
     4981 ccagtatctc tattggggat attttagtct ttcagtctcc aacctggaat ggctttgaat
     5041 ttgatcgtct cttgtttgac aagctaaagg atatgcaggt gaaaattatt tgttttatcc
     5101 atgatgttgt tcccctcatg tttgatagta actattatct catgaaagac tatatgtaca
     5161 tgtataatct atcagatgtt ttgatagtgc catcagagag aatgaaaaca cgcctgatgg
     5221 aagaaggatt gacgactaag aagattcttg ttcaagggat gtgggatcat cctcatgatt
     5281 tatccttata cacccctgct tttaaaaaag aacttttttt tgctggaagt ttagagcgtt
     5341 ttccagactt acaaaattgg tctcaagata cgcctttgag agtattttca aataaagggg
     5401 aagctagttc tagtgctaga aatctcagca tcgaaggatg gaaaaaagat gaggaattgt
     5461 tgctagaatt atcaaagggt ggatttggcc ttgtctgggg aacccatcaa aatgagggag
     5521 aaagtaacca atactatacc ttgaatatat ctcataaggt gagtacctat ctgacagcgg
     5581 gcatcccagt cattgtacca agtagcttgt caactgctga atttatagta gatcaaggct
     5641 taggctttgt ggcgaatagt ctagaggaag ttcatgagat agttgataaa atgaatctac
     5701 aagaatatca agaaatgacg aatcggataa aaacctttag ttatttgcta aaagaaggtt
     5761 attttactaa aaaattattt gtagatgcaa tttaccattt gggagttgaa taagagaaca
     5821 agatgattaa aacaattgta ttagctggtg atcgtaatta catcaggcag ttagaaacaa
     5881 ccataaaatc tattttatac cacaatcgag atgttaagat ttatatttta aatcaagata
     5941 ttatgccaga ttggtttcgc aaaccacgaa aaatagctcg catgttaggt agtgagatta
     6001 tcgatgttaa actacctgaa caaactgtgt ttcaagattg ggaaaagcaa gatcacatta
     6061 gtagcattac ctatgctaga tattttattg cagattatat ccaagaagat aaggttttat
     6121 atttagacag tgatttgatt gtaaatactt ctttagagaa attatttagt atttgtttag
     6181 aagaaaaatc actcgcagca gttaaagata cagatggaat tacatttaat gcaggtgttt
     6241 tattaatcaa caataaaaaa tggcgtcaag agaaattaaa agaacgacta attgaacaga
     6301 gcattgttac aatgaaggaa gttgaagaag gccgtttcga gcattttaat ggtgatcaaa
     6361 cgatttttaa tcaggtcttg caagatgatt ggttagaact aggtagagct tataatttac
     6421 aagtaggaca tgatgtggtt gctttgtata ataattggca ggaacatctg gcttttaacg
     6481 ataaaccagc ggtgattcat tttacgacct acagaaagcc atggactacc ttgatagcca
     6541 atcgttaccg tgatttatgg tgggaatttc atgatttgga gtggaatcaa attttacaac
     6601 accatatagg agagtttgaa atgacatcgc ctctagataa ggaattttct tgtttaactt
     6661 tgacaaattc ccaagattta gaaggaatag aagagctagt tacagctcta cctgaggtgg
     6721 tatttcatat cgcagcttgg acggatatgg gagataaatt aaaaaaatta gctgtatata
     6781 ataatgtgag attgcatcca caaattgttc ctcctgtatt agataagctg aaaaagtcaa
     6841 caaatctata tttggatatc aatcatggta gtgcagatga gaacttttta aaatctttgc
     6901 aagaacaaga aaaaacgcta ctagcttttc aatcgactca gcacggagag ttaggacaaa
     6961 tcgttttcga aaatgggaaa gtttccttta tgattgatac gattaaagat tttaagaaaa
     7021 acggacatct tacctgtttt cgacaacttc caagtttaac ttgtttaacg tttacggctt
     7081 ctcaggatat cgaacaattg gattacttgg ctggacagtt gccaaatgtt gtttttcaag
     7141 ttgctgcttg gacagctatg gggccaaaat tatatgattt gtctaatcgt tatcctaata
     7201 ttcagctcta tccggcaatt tctagagata agctagacga gttgaaggag aagatggatg
     7261 cttatttaga tatcaaccta ctgacttcaa catccgatat cgttgcagaa atggctcatc
     7321 tatctaaacc tatactagcc ttttataaat ctcaaaatgg gaataatggc caaaggttgt
     7381 attcaagtga acatcctgaa cgaatgttgg ctgatttgca aaaattgata actaaggata
     7441 tgctagaaaa accgcttgat ataatccagg tgaaagggat agatgaaacc ttggattata
     7501 ttattgaaca caactcttct ttagttcgtt ttggagacgg agaagtcaat ttgatgtggg
     7561 gtttgcctat accttatcaa aatcatgatc tagagttagc taaccaatta aaacatattg
     7621 tgggttttga aagtgacgag aaattagtgg tttgtttacc tgatgctttt gacgatcgtt
     7681 ttgtctttac ttggtgggct acaccattct ggaaagaaca tatgaatgtt tatatggatt
     7741 tttataaaga gttgtgtaag ggttcatggt atggctccac ctttatctcg cgtccataca
     7801 ttgattatga agataagagt aaggcaaaag gacaatttga aaagctaaag agtatttggg
     7861 agaataggga tattctgatt gtagagggga ttacatctcg ctctggggtt ggaaatgatt
     7921 tatttgataa ggtcaaatct gtgaaaagga ttatttgtcc atctcataat gcttattccg
     7981 ttgtcgataa cattcaagag gaaattatga aacatgctga aggaagactg attttatgta
     8041 tgctgggtcc tacagcaaaa gttctgagtt ataatctatg ccagatgggc tatcaagttt
     8101 tggatgtagg ccatgttgac tcagagtatg aatggatgaa aatgggagct aaaactaagg
     8161 ttaaattttc tcataaacat actgcagaac ataatttcga ccaagatatt gaatttattg
     8221 atgatgaaac ctataacagt cagattgttg cacgaatatt aaactagact atttaaaata
     8281 aatgataagg atttaaaatg agaaatacca aacgcgctgt agtatttgca ggtgattacg
     8341 cttatattcg acaaatcgaa acggcgatga agtcactctg tagacacaat agtcatttga
     8401 aaatttatct gctaaatcag gacattcctc aggaatggtt tagtcaaata agaatatatt
     8461 tacaagagat ggggggcgac ttgattgact gcaagttaat tggctcacag tttcaaatga
     8521 attggtctaa taaattacct catatcaatc atatgacatt tgcacgctat tttattccag
     8581 attttgtaac agaagataaa gttctctatc tagatagtga tttgattgtg actggtgatt
     8641 tgaccgattt gtttgaatta gacttaggtg aaaattattt ggcagcagct cgttcttgct
     8701 ttggagcagg agtcggcttc aatgctggtg ttctcttgat taacaacaaa aaatggggat
     8761 ctgaaactat tcgacaaaaa ttgattgact taacagaaaa agaacatgag aatgtggaag
     8821 aaggagacca gtcaattttg aatatgttgt ttaaagatca atatagttcc cttgaagatc
     8881 aatataattt tcaaatagga tatgattatg gggcggcagc ctttaaacat caattcattt
     8941 ttgatattcc gctcgaacca ctgccactaa ttttacacta tatttctcag gataagcctt
     9001 ggaatcaatt ttctgttgga cgtctaagag aagtttggtg ggaatactct ttgatggatt
     9061 ggtctgttat tttaaatgaa tggttttcaa agagtgtgaa gtaccctagt aaatcacaaa
     9121 tatttaagtt gcaatgtgtt aatttaacga attcttggtg tgtcgagaaa atcgattatt
     9181 tggcggagca attgccagaa gttcattttc atattgttgc ttatacaaat atggcaaatg
     9241 aactactagc tttaacgcgt tttcctaatg ttaccgtata tccaaattcc ttaccaatgt
     9301 tattggaaca aatagtaata gcttcagatt tgtatttgga tttgaatcat gatcgaaaat
     9361 tagaagatgc atatgagttt gtgcttaagt acaaaaaacc aatgatagct ttcgacaata
     9421 cttgctctga aaatctttct gagatttcat atgaaggtat ctatccaagc tccattccga
     9481 aaaaaatggt tgcagcaatc agatcttaca tgaggtagag aacagtatga gaaaatcaat
     9541 agtattagcg gcagataatg cctatcttat tcctttagag acgactataa agtctgtatt
     9601 gtatcacaat agagatgttg atttttatat tctcaacagt gatatagctc ctgaatggtt
     9661 taaattattg gggagaaaaa cggaagttgt gaattctaca attcgcagtg tacacattga
     9721 taaagaactt tttgaaagct ataaaacagg acctcatata aattatgctt cttactttag
     9781 attttttgtg acagaagtgg ttgaatctga tagggtattg tatctggatt ccgatatcat
     9841 tgtaactggg gaactagcta ctttgtttga gatagatctc aaaggatatt caattggtgc
     9901 tgttgatgat gtctatgcct atgaaggacg aaaatctgga tttaatgctg gtatgttact
     9961 aatggatgtt gtaaaatgga aagaacattc tattgtcaat agtttattgg aattagcggc
    10021 cgagcagaat caagttgttc atcttgggga tcagagtatt ttaaatattt attttgagga
    10081 taattggcta gcgttagata aaacatataa ttatatggtg ggtgttgata tttatcacct
    10141 tgctcaagaa tgtgaacgtc tagatgacaa tctacctaca attgttcact atgctagtca
    10201 tgataaacct tggaatacat atagtatatc tagactacgt gaattatggt gggtttatag
    10261 agatttggat tggtcagaga ttgcttttca acgttccgat ttaaattatt ttgaaagaag
    10321 caatcagtct aaaaaacaag tgatgtttgt gacatggagt gcagatataa aacatttaga
    10381 gtatttagta caacggttac ctgattggca ttttcatttg gctgcaccgt gtgattgttc
    10441 tgaggagctg atctctctat cacagtatac gaatgtaaca gtatatcaaa atgtattaca
    10501 tagtagaatt gattggctat tggacgattc tatagtttat ttagatatta atacaggtgg
    10561 agaggttttt aatgtagtta caagggcaca agaaagtggc aagaaaatct tcgcttttga
    10621 tatcacacgt aaaagtatgg atgatggact ctatgacggt attttttctg tggagagacc
    10681 agatgattta gtggatagaa tgaagaatat agagatagag taatgagtga attaattagt
    10741 gttgtggtac cgatatacaa tacgggaaaa tatttagtgg ggtgtgtcga gcatattctg
    10801 aagcaaacct atcaaaatat agaaattatt ttagttgatg acggttctac ggataattct
    10861 ggggaaattt gtgatgcttt tatgatgcaa gataatcgtg tgcgagtatt gcatcaagaa
    10921 aataaggggg cagcacaagc taaaaatatg gggattagtg tagctaaggg agagtacatc
    10981 acgattgttg attcagatga tatcgtaaaa gaaaatatga ttgaaactct ttatcagcaa
    11041 gtccaagaaa aggatgcaga tgttgttata gggaattact ataattatga cgaaagtgac
    11101 gggaattttt atttttatgt aacagggcaa gatttttgcg tcgaagaatt agctatacaa
    11161 gaaattatga accgtcaagc aggagattgg aaattcaata gctcggcctt tatattgccg
    11221 acatttaagt tgattaaaaa agaattattc aatgaagttc acttttcaaa tggtcgccgc
    11281 tttgatgatg aagcaactat gcatcgcttt tatcttttag cctctaaaat cgtctttata
    11341 aacgataatc tctatctgta tagaagacgt tcaggaagca tcatgagaac ggaatttgat
    11401 ctttcctggg caagagatat tgttgaagtg ttttctaaga aaatatcgga ttgtgtcttg
    11461 gctggtttgg atgtctccgt tctgcgtatt cgatttgtca atcttttaaa agattataag
    11521 caaactttag aataccatca attaacagat actgaggaat ataaagatat ttgtttcaga
    11581 ttaaagttgt tttttgatgc agaacaaaga aatggtaaaa gttgaaataa aagaattgtt
    11641 atttaccata tcacaaacaa tgaaggtgag gggagtgttt tatgactaag atttattcgt
    11701 caatagcagt aaaaaaagga ctatttacct tatttctact gtttatctat gtattgggaa
    11761 gtcgtattac tctccctttt gttgacctaa atactaaaga ttttttagga ggttcaacag
    11821 cctatctagc cttctcagcc gccctaacag gtggaaatct aagaagtttg tcaatttttt
    11881 ctgttggatt gtccccttgg atgtcagcta tgattttatg gcagatgttt tctttttcta
    11941 aacggttggg tttaacatct acgtctatag aaatacaaga tcgccgtaaa atgtacctga
    12001 ccttgatgat agctgtcatt caatcattgg cagttagctt gagactgcca gtacaatcct
    12061 cctattctgc aatattggtt gttctaatga atacaatatt gctgatagca ggaacatttt
    12121 ttcttgtttg gttgtcagat ttaaatgcga gtatggggat tggaggttct atagtcattc
    12181 tcctatccag tatggtttta aatattcctc aggatgtttt ggaaacattt cagacagtac
    12241 acattccaac agggattatt gtgttacttg ctttattaac ccttgtcttt tcttatttac
    12301 ttgcccttat gtatcgagct cgctatttgg ttcctgttaa taaaattggc ttacacaatc
    12361 gatttaaacg ctattcttat ctcgaaatca tgttgaatcc tgcaggtggg atgccttata
    12421 tgtatgtgat gagttttctt agtgtaccag cttatttgtt catcttgttg ggatttattt
    12481 tccctaatca ttcagggtta gcggctttat caaaggaatt tatgattgga aagcctttgt
    12541 gggtctatgt ttatatttcg gtcttatttt tatttagtat catttttgct tttgttacga
    12601 tgaatggaga agagattgca gaccgtatga aaaaatctgg agaatacatt tatggtattt
    12661 atccaggtgc ggatactagt cgatttatta atcgattggt ccttcgtttc tcagtcatag
    12721 gtggtctctt taatgtggtt atggcaggtg gtcccatgct ttttgttttg tttgatgaaa
    12781 agttattacg attggcaatg attccaggtt tgtttatgat gtttggaggc atgattttta
    12841 cgattagaga cgaggtcaag gctttaaggc taaatgagac ctatagacct ttgatttagg
    12901 agacttttat gtattatttt attccagctt ggtatgggtc agaaagaaca tggcatgcag
    12961 atatcactcc atggtatttt tctcattttc gtctagagtt tgatgatacc tttcaccaga
    13021 ttcggctctt tcaagagcaa gatatagatt ctcgtctatt agtattagct taccagcctc
    13081 atctacgtta ttttttatat agacatggtg tgttagaaac ggatacttat tccgtttttg
    13141 atgttatgca agattttcat aatctccata cccaagtttt aagcattaga gatattgagt
    13201 gggatgatga ctgtgaattt atttatagtc cctttacgat tatcgttcaa aaaaatggga
    13261 agaaatttgc taaggttgaa catggagttg aaggcttcat cagtgatata cagtattttg
    13321 gaccgaatgg tcaaatacat atgcactata tcatggatga tcgagggttt atatcgagta
    13381 ttattttttt tgaagatggg caagcagcct atcaagaata tttgaatcct aagggagttt
    13441 ggcaatttag agagcgttta aaagaaggag gacaggtaga agtcaatcca attttgggtt
    13501 atcgctttaa aatgcttacc tatcaaaata tgggagatct ggtggcagaa ttttttgaga
    13561 attatctgca aacgtatgtg aaggatcagg atatttttat gcttccttct cattctcatc
    13621 atgaccagtt ggtactagat cgtttaccta gtactaatcc taaactgttg agtctgttca
    13681 ttggacgtaa tcctcaagat acctttaggg atttagatgt aacttttgaa aaatcggatt
    13741 tgattttggt ggatagagag gatagtttac gattgttgca ggagttgtat cctgaacgaa
    13801 tgcatcaatg ttatcattta tcatcttttg acacccgatt acgattggga cgaagccaaa
    13861 ctaagaaaga atccatcatt tattttcaac tggattttga gcaggggatt gataatcaag
    13921 ctctgcttca agtcttgtcc tttgtcgctg aaaataagga tactgaggtg atttttggag
    13981 cctttgctgc tagtcaggag caaatgaatg aggttgaagg gattgttgag tctttcatcc
    14041 aagaaaacat tcaatccgaa aatctgggaa aggcgattga ttatggtgat gcagaaaatc
    14101 ctctggaaga aaatcaacac caggacttac gcttacagtt tgttaacttg aatgatgagt
    14161 tagatttgat aaaaacacta gaatttgtcc gtttgattgt ggatttaaat agacatcctc
    14221 atctctacac acagattgct gggattagtg caggaattcc tcaaatcaac ctagttgaaa
    14281 ccgtctatgt tgaacattta aaaaatggtt atttgttagc agatgttaca gaattttcta
    14341 aggctgcaca ttattacaca gataggttga aggagtggaa tgagtccttg atatattcaa
    14401 ttgataagat taaggagcac acaggacaac aatttcttgg aaaattagag aaatggatag
    14461 aggaggttaa aaatgtcaaa ggaacttaat attttacaga taggacttgc caattgggaa
    14521 aatcactatg acatacctga aaatatgagt tggtattatt tttacccaaa ctcatcaaaa
    14581 gcccttcgtg aaataattga aaaagaggat attaaccgtt ttcatgcagt tttaatagaa
    14641 gatggtcagt attccagaga cttattttcc tatgtaaaat attttgaacc ttatactttg
    14701 ttctataacc agaatctaca aataaatgat agagaggttg tggattttct aaaaaaacga
    14761 tgtgcacaag caattgattt tttaagtccc caacaactaa tcaatgattt aagtaaatct
    14821 ctttttggcg gtgggtatgg tgataaactc tttcctccga cgatacaagt caatccaaat
    14881 tttacaggag ctatttctta tcaaggattg gattatgtca gtttggaagg tgagtttggg
    14941 caagattttg cccagcttgc ctattgggct tataatatta tggtgcaaaa aacactccct
    15001 attgagttgt ggcttgaata tgagaaggaa ggcaattgtg actttcgttt ggttatccgt
    15061 aaaatgtgga gtgggtctgt tgatgatttc tttgaagaag taatagtatc tgaaaaagac
    15121 ttggagcaag cactttttat ggatagtcga gacggagact actttctctc gatatctgtt
    15181 gaagcaagag gtcgtggaac tatcaaacta ggtaatcttc atcaacgatg gagtcgaaaa
    15241 caatttggta agtttgtact tggtggaaat atcctacatg attccaagcg tgatgaaata
    15301 aactatttct tccatccagg tgattttaaa ccgcctttga ctgtctattt tgcaggttat
    15361 cgacctgcag aaggattcga gggttacttt atgatgaaaa ctcttggatg tcccttcatt
    15421 ttattttctg atccacgttt agagggggga gctttttatc tcggaacgga tgagctagag
    15481 ggaaaagtaa aggatacgat cactcactat cttgattatt taggctttga tcataaggat
    15541 ttgattttat caggtctttc tatgggaacg tttccggctc tctattatgg tgcttctttt
    15601 gaaccccatg ccatcatagt tggtaagccc ttggctaatt taggaactat agctagtcgt
    15661 ggacgtttgg acgcaccggg tgtctctaac ttagcttttg attgtttaat tcatcataca
    15721 ggtgggacaa gttctcaaga tatgacggag ttggatcagc gtttttggaa aatttttaaa
    15781 caagcaaatt tttcaaagac aacctttggt ttatcctata tgaaagatga agaaatggat
    15841 ccacaagcct atgaacaatt agtgtcttat ctgtgtaata caggtgcgaa gattttatct
    15901 aaaggaactg ctggacgaca caatgatgat acagatacca atatttcttg gtttttgcac
    15961 ttttatagaa tggtcttaga gactggtttt ggaagggaga aaagatgatt attacacaga
    16021 gacagtctat ttattgggga gaagttggtg ggacttatat gtatggaaca actgtatctt
    16081 attaccctga caaaagtgtt cgtctgtata atcctctatt gccatctggt gagattctaa
    16141 agacttggtt ttctagtgtc aattaccagg ctgcacgaac ccaacctcag cttcccttat
    16201 taaaaagaaa gcaggagtat caactatcac tggtttttga ttgccagcct gaaaatggag
    16261 tttataccaa gataactttt tttgaccgct atggtgatat tttagaaaaa aaggtagaaa
    16321 aagcgaaaga tttcatattt acttatccag aagatagtta tacttatcaa gtttctcttt
    16381 taagtgctgg atttgagtcc ttaacttttt atcatttttc tatcaaggag atcagaagtg
    16441 tttagacgtt taggtcaaga tttccagctt aggaaagtga aaaagatttt aaagcagatt
    16501 aatgccctga aaggcaagat gtcctctctt tcggatcaag aattagtagc taaaacagta
    16561 gagtttcgtc agcgtctttc cgagggagaa agtctagacg atattttggt tgaagctttt
    16621 gctgtggtac gtgaagcaga taagcggatt ttagggatgt tcccctatga tgttcaagtc
    16681 atgggagcta ttgtcatgca ctatggaaat gttgctgaga tgaatacggg ggaaggtaag
    16741 accttgacag ctaccatgcc tgtctatttg aacgcttttt caggagaagg agtgatggtt
    16801 gtgactccta atgagtattt atcaaagcgt gatgccgagg aaatgggcca agtttatcgt
    16861 tttctaggat tgaccattgg tgtaccattt acggaagatc caaagaagga aatgaaagct
    16921 gaagaaaaga agcttatcta tgcttcggat atcatctaca caaccaatag taatttaggt
    16981 tttgattatc taaatgataa cctagcctcg aatgaagaag gtaagttttt acgaccgttt
    17041 aactatgtga ttattgatga aattgatgat atcttgcttg atagtgcaca aactcctctg
    17101 attattgcgg gttctcctcg tgttcagtct aattactatg cgatcattga tacacttgta
    17161 acaaccttgg tcgaaggaga ggattatatc tttaaagagg agaaagagga ggtttggctc
    17221 actactaagg gggccaagtc tgctgagaat ttcctaggga ttgataattt atacaaggaa
    17281 gagcatgcgt cttttgctcg tcatttggtt tatgcgattc gagctcataa gctctttact
    17341 aaagataagg actatatcat tcgtggaaat gagatggtac tggttgataa gggaacaggg
    17401 cgtctaatgg aaatgactaa acttcaagga ggtctccatc aggctattga agccaaggaa
    17461 catgtcaaat tatctcctga gacgcgggct atggcctcga tcacctatca gagtcttttt
    17521 aagatgttta ataagatatc tggtatgaca gggacaggta aggtcgcgga aaaagagttt
    17581 attgaaactt acaatatgtc tgtagtacgc attccaacca atcgtccgag acaacggatt
    17641 gactatccag ataatctata tatcacttta cctgaaaaag tgtatgcatc cttggagtac
    17701 atcaagcaat accatgctaa gggaaatccc ttactcgttt ttgtaggctc agttgaaatg
    17761 tctcaactct attcgtctct cttgtttcgt gaagggattg cccataatgt cctaaatgct
    17821 aataatgcgg cgcgtgaggc tcagattatc tccgagtcag gtcagatggg ggctgtgaca
    17881 gtggctacct ctatggcagg acgtggtacg gatatcaagc ttggtaaagg agtcgcagag
    17941 cttgggggct tgattgttat tgggactgag cggatggaaa gtcagcggat cgacctacaa
    18001 attcgtggcc gttctggtcg tcagggagat cctggtatga gtaaattttt tgtatcctta
    18061 gaggatgatg ttatcaagaa atttggtcca tcttgggtgc ataaaaagta caaagactat
    18121 caggttcaag atatgactca accggaagta ttgaaaggtc gtaaataccg gaaactagtc
    18181 gaaaaggctc agcatgccag tgatagtgct ggacgttcag cacgtcgtca gactctggag
    18241 tatgctgaaa gtatgaatat acaacgggat atagtctata aagagagaaa tcgtctaata
    18301 gatggttctc gtgacttaga ggatgttgtt gtggatatca ttgagagata tacagaagag
    18361 gtagcggctg atcactatgc tagtcgtgaa ttattgtttc actttattgt gaccaatatt
    18421 agttttcatg ttaaagaggt tccagattat atagatgtaa ctgacaaaac tgcagttcgt
    18481 agctttatga agcaggtgat tgataaagaa ctttctgaaa agaaagaatt acttaatcaa
    18541 catgacttat atgaacagtt tttacgactt tcactgctta aagccattga tgacaactgg
    18601 gtagagcagg tagactatct acaacagcta tccatggcta tcggtggtca atctgctagt
    18661 cagaaaaatc caatcgtaga gtactatcaa gaagcctacg cgggctttga agctatgaaa
    18721 gaacaaatcc gtgcggatat ggtgcgtaat ctcctgatgg ggctggttga ggtcactcca
    18781 aaaggtgaaa tcgtgactca ttttccataa gaggagaaaa tatgacaatt tacaatataa
    18841 atttaggaat tggttgggct agtagcggtg ttgaatacgc tcaagcctat cgtgctggtg
    18901 tttttcggaa attaaatctg tcctctaagt ttatctttac agatatgatt ttagccgata
    18961 atattcagca cttaacagcc aatattggtt ttgatgataa tcaggttatc tggctttata
    19021 atcatttcac agatatcaaa attgcaccta ctagcgtgac agtggatgat gtcttggctt
    19081 actttggtgg tgaagaaagt cacagagaaa aaaatggcaa ggttttacgt gtattctttt
    19141 ttgaccaaga taagtttgta acctgttatt tggttgatga gaacaaggac ttggttcaac
    19201 atgccgagta tgtttttaag ggaaacctga ttcggaagga ttacttttct tatacgcgtt
    19261 attgtagcga gtattttgct cccaaggaca atgttgcagt cttataccaa cgaacttttt
    19321 ataatgaaga cgggactcca gtctatgata tcttgatgaa tcaagggaag gaagaagttt
    19381 atcatttcaa ggataagatt ttctatggaa agcaagcttt tgtgcgtgcc tttatgaaat
    19441 ctttgaattt gaataagtct gatttggtca ttctcgatag ggagacaggc attggtcagg
    19501 ttgtgtttga ggaagcacag acagcacatt tagcggtagt tgttcatgcg gagcattata
    19561 gtgaaaatgc tacaaatgag gactacatcc tttggaataa ctattatgac tatcagttta
    19621 ccaatgcaga taaggttgac ttctttatcg tgtctactga tagacaaaat gaagttctac
    19681 aagagcaatt tgccaaatat actcagcatc agccaaagat tgttaccatt cctgtaggca
    19741 gtattgattc cttgacagat tcaagtcaag ggcgcaaacc attttcattg attacggctt
    19801 cacgtcttgc caaagaaaag cacattgatt ggcttgtgaa agctgtgatt gaagctcata
    19861 aggagttacc ggaactaacc tttgatatct atggtagtgg tggagaagat tctctgctta
    19921 gagacattat tgcaaatcat caggcagagg actatatcca actcaagggg catgcggaac
    19981 tttcgcagat ttatagccag tatgaggtct acttaacggc ttctaccagc gaaggatttg
    20041 gtctgacctt gatggaagct attggttcag gtctacctct aattggtttt gatgtgcctt
    20101 atggtaatca gacctttata gaggatgggc aaaatggtta tttgattcca agttcatctg
    20161 accatgtaga agaccaaatc aagcaagctt atgccgctaa gatttgtcaa ttgtatcaag
    20221 aaaatcgttt ggaagctatg cgtgcctatt cttaccaaat tgcagaaggc ttcttgacca
    20281 aagaaatttt agaaaagtgg aagaaaacag tagaggaggt gctccatgat tgaactttat
    20341 gatcgttata gtcatgaaag tcgagattta catgaaagtc tagtcgctac tggtctttct
    20401 caacttggag tggtcatcga tgcagatggt tttctgcctg atggtctgct ttctcctttt
    20461 acctattatc taggttacga ggatggaaaa cctctctatt ttaatcaagt tcccgtttca
    20521 gatttttggg aaattttagg agataatcag tctgcttgta ttgaagatgt gacgcaggag
    20581 agggctgtca ttcattatgc tgatggaatg caggctcgct tggttaaaca ggtagactgg
    20641 aaagacctag aaggtcgagt acgtcaggtt gaccactata atcgtttcgg aacttgtttt
    20701 gctaaaacca cttatagcgc agatagcgag ccgattatga cagtttacca agatgtcaat
    20761 ggtcaacaag ttttactgga aaaccatgtg acgggtgata tcttattgac tttgcctggt
    20821 cagtccatgc gttactttgc aaataaagtt gaatttatca ccttcttttt gcaagatttg
    20881 gaaatagaca ccagtcagct tatctttaat actctagcga ctcctttctt ggtttccttt
    20941 cattatccag ataaatctgg ctcggatgtc ttggtatggc aggaacctct ttatgatgcc
    21001 attccaggta atatgcagtt gattttggaa agtgataatg tgcgtactaa gaagatcatc
    21061 attccaaata agacgactta tgagcgcgct ttagagttaa ctgacgagaa ataccatgat
    21121 cagtttgtgc acttgggtta tcattaccag ttcaaacgtg ataatttcct aagacgagac
    21181 gccttaatct tgaccaattc agatcagatt gagcaagtag aagcaatcgt agaagccttg
    21241 cctgatgtta ccttccgtat cgcagcagtg acagagatgt cttctaagct cttagacatg
    21301 ctttgctatc ctaatgtggc cctttaccag aatgctagtc cacagaagat tcaggagctg
    21361 tatcaactgt cggatattta cttggatata aaccacagta atgagttgct acaggcagtg
    21421 cgtcaggcct ttgagcacaa tctcttgatt cttggcttta atcagacggt gcacaataga
    21481 ctttatgtcg ctccagacca tctatttgaa agtagtgaag ttgctgcttt ggttgagacc
    21541 attaaattgg ccctttcaga tgttgatcaa atgcgtcagg cacttggcaa acaaggccaa
    21601 catgcaaatt atgttgactt ggtgagatat caggaaacca tgcaaactgt tttaggaggc
    21661 taacatgtca gaggaagatt tattttacaa agacgttgaa ggccgcatgg aagagttgaa
    21721 acaaaaaccc atcaagaagg aaaaagaaac ccgaggggaa aagattagta agactttttc
    21781 acttttactg ggtttgatga ttctgattgg tttgctcttt actttgctgg gaattttgag
    21841 gtagatctat gattgacata ctaattgttt tagctattat cctatctctt gctttgattg
    21901 tattggtaac tatacaaccc cgtcaaaatc aactattttc catggatgcc actagtaata
    21961 ttggtaaacc aagctactgg cagagcaaca ccttggtcaa ggtgctcact ttattggtga
    22021 gtttggcttt atttgttcta ctattaacct ttatggtgat tacttataaa taaaagaaaa
    22081 cttcagatat tcaccttttg tggattggtc tgaagttttc ttttttatac tcaatgaaaa
    22141 tcaaagagca aactaggaag ctagccgcag gctgctcaaa acacggtttt gaggttgtgg
    22201 atagaactga cgaagtcagc tcaaaacacg gttttgaggt tgtggataga actgacgaag
    22261 tcagtaacat atatacggca aggtgaagct gacgtagttt gaagagtatt actgtctata
    22321 tttttggtaa aaatcaactt ttacttggat gaaggttttg gcttcacgta ggagttgaag
    22381 aagggtggcg cgggtttcaa attcttctct tgtcttgggc agactgcggt tccggaagac
    22441 ttccagataa cgttcaattt catctagcaa atcagaagca ggattggtct ggctcagttg
    22501 acctgcaatt tttgaaaaga gttgcgctaa gatcaggctt tcactggcgg caaggtgaca
    22561 agtgttaatc tgttgggcca tgtttctcag gatacgactt tgtcgctgtc tcatctcaaa
    22621 gtagtggata tggtagtcgg tctggtgaaa gaggtggtca gagtgatcca aatagaccag
    22681 tctgagggct tctttcaaaa gcgtgtctaa ttctgctacc agctgtgctc ggttgcgtcc
    22741 gtctcctctg gataaatagt atttgaagcg ctggaggata tcttttaact tttcttccac
    22801 cagcgtgtgg tagtgctgga tttcctcttc tcgtgaaggc atatagagat taacaagcaa
    22861 ggcaaatcct gtaccaatag caaagagaag gaattcgttg actaggaggt ctggagaggt
    22921 tgactcttga accaagagat ggctaaccaa aaccgtgctt ggtgtgatgc caatttccca
    22981 gcccatcttg taggctaaag gaacgtagaa ggccagatag aggccgagac tccagatatg
    23041 aaatccgctc aagtgaaaag ctagaacacc gatagccaga gctagaagca tagaaaaaag
    23101 acgattgcga gccagtttta aagtacttct acgcgtatca gataggctca agagagcgat
    23161 aattccagcc gaaactgctg acgaaagatt gagaaaataa gcaagcaggc aggcaagaca
    23221 ggtagctaag atgagcttgg tcgtacgttg gctaatagac ataagaattt cctaataagt
    23281 tagaataaaa gcgtaaaaga caagacatga gcaggcttgc cttgatgagt tattttttac
    23341 gggttgctgc gtattcggca acggcggtaa agaggacatc tgtagaagag ttaagggctg
    23401 tttcacatga gtcttggatg acaccaatca caaaaccaac cccaacaatt tgtatggcaa
    23461 tatcgttaga aataccgaaa aggctacaag caactgggat aagaaggagg gaacctccgg
    23521 caatacctga agcaccacag gctgagatag ctgctaccac actgaggaca aaggctgtgg
    23581 caaagtcaac aggaattcca agagtgttaa ctgtaacaag ggtcaaaagg ttaatggtaa
    23641 tcgctactcc agccatattg atagtagaac cgagtgggat agaaacagaa taggtatctg
    23701 ggttgagtcc aaggtcatgg cagagtttca tattgacagg aatgttagcc gcagaactac
    23761 gagtgaaaaa ggctgtcaca ccgctgacac ggaggcagtt ccaaactaga gggtaaggat
    23821 tgcgtctcat aaagaagaag gcaatcaaag ggttgaccac aggggcaaca aaaagcatag
    23881 tcgttactaa tagaaccaat aaaataccgt agttggcaag gcttccgact cccttgtcag
    23941 aaatggtttt aaaaacaaga ccaaggattc caaatggagt cagattgatg atccattcga
    24001 caagtttaga agtcacgtca gcgatagttt ttagcaattc tttactattt ttactggctt
    24061 ctctcatagc gattccaaaa atgactgccc aagataagat tccaatatag ttagcagtaa
    24121 gcagggcgtt gactgggctg tcaaccagtt tgagcaagag gttgctgagg acctgcccaa
    24181 tcccatctgg tggtgcaatt tcagtattgg cactatttag ggtaatttca atagggacga
    24241 tgaaacttgc tagtacagct acaagagcag cggcgaaagt ccctatcata ggatatacaa
    24301 gaaaacaaca gttttcatat tgctatcttg tcccttttga tgttgggaaa gggcattggc
    24361 aacgagggca aagactagga taggagcaac agcttttaga cctccaacga ataaatcccc
    24421 gagtagccca atccctgaga gattaggaag ggtcagtcct aggattcccc ataaagcata
    24481 ccaatcaaga tacgcttgac aaggcttgcc ttattccaag catgaatgat tcttttcata
    24541 ataatctcct ttttgtgtag tgattatgat tatagtataa atgatagaca aaatcaagaa
    24601 ttttctgtct attttttgaa tatgtatgga gaatgagact gatgaaaata tggtataatg
    24661 aaataaagga gttttatatg caaaaattta ttcaggctta tattgaaaag ctagatgtga
    24721 caaccattat cgagaatatt ctaaccaagg tcatttctct tttactgctt ttgattgtat
    24781 tttatattgc taaaaaaatg cttcatacca tggtgcagag aattgtcaaa ccttctctaa
    24841 aaatgtctcg tcatgatgtc ggacgccaaa aaaccatctc acgtttacta gaaaatgtgt
    24901 ttaattatac gctatatttc tttttactct actgcatttt gtcgatttta ggtttgccag
    24961 tttctagttt gctggctgga gctggtattg ctggggtagc gattggtatg ggagcccaag
    25021 gctttctatc tgatgtcatc aatggctttt tcatcctctt tgaacgtcaa ctggatgtgg
    25081 gagatgaggt cgttctgaca aatggaccga ttactgtatc gggtaaggtt gtcagtgtgg
    25141 gaattcgtac gacacagctt cgtagcgagg agcaagccct tcactttgtc cctaaccgaa
    25201 atatcacagt tgttagcaat ttctcacgca cagactagac ctgttatttt aagtaatttg
    25261 tggtacaata gagggagttt aataaggaga aaagatggtt ttagaaaagc agttgggcaa
    25321 tggttgtacc tggatagacc tagacctagg aaagttgaat aaactagaag acctttctga
    25381 aatttacggt ttggacaagg aaaccattga atacgcactg gatagaaacg agcgcgccca
    25441 catggactac caccgtgaaa gtgggacggt tacctttatc tataatgtcc tagacgtaaa
    25501 aaaggacaag gcctactatg agacttttcc catgaccttt atcgtcgagc atcgtcgcct
    25561 gattaccatt agtaatacca agaacgccta tgtcattgaa cagatgactc gttatctgga
    25621 gaaccatgac acgctttcga tttataagtt tctctttgcc agtctggaaa tcatcagcaa
    25681 tgcctactat cctgtcattg agcagatgga caagagtagg gatgaggtca atgacctctt
    25741 gcgccagcga actaccaaga aaaacctctt tgccctgtct gatttggaga ctggtatggt
    25801 ttatctgacg gcagctgcca aacaaaatcg gattttgtta gagcatattc aaggtcatgc
    25861 cttgtatcgt agttttgatg agattgagag agaacagttt gatgatgcca tgattgaggc
    25921 tcatcagctg gtatccatga cagacctaat ctctcagatt ttacagcagc tttcagcctc
    25981 ttacaacaat attctaaaca ataatctgaa tgacaatttg acaaccttga ctattatttc
    26041 agtcttgcta gctgttttgg cagtcgtgac aggctttttc ggaatgaatg ttcccttacc
    26101 tttaacagat gagccccatg cttggctcta tattagtttg gctagtgcag gtttgtggat
    26161 tgttttatcc ttgttactaa ggaaaattgc gaaaaaaagt taagaaaagg agccagaatg
    26221 gcgattgaaa attatatacc agattttgct gtggaagcag tctatgatct gacagtccca
    26281 agcctgcagg cgcagggaat caaggctgtt ttggtcgatt tggataatac cctcattgct
    26341 tggaacaacc ctgatggaac gccagagatg aagcaatggc tacatgacct tcgggacgcg
    26401 ggtattggca ttatcgtagt gtcaaataac accaaaaaac gcgttcaacg agcagttgag
    26461 aaatttggga ttgattacgt ttactgggcc ttgaagccct tcacatttgg tattgaccgt
    26521 gctatgaagg aattccacta tgacaaaaag gaagtggtca tggttggtga ccagctcatg
    26581 acagatatac gagcagccca ccgtgcaggg attcggtcaa ttttagtcaa acccttggtc
    26641 caacatgact caatcaaaac gcagattaac cgaactcgtg agcgtcgtgt tatgagaaaa
    26701 atcactgaaa agtacggacc gattacatat aaaaaaggaa tttaactatg gaagaaattc
    26761 tctgtattgg ttgtggagca accattcaga cgacagataa ggctggtctt ggttttaccc
    26821 cccagtcggc acttgaaaaa ggtttggaga ctggcgaagt ctattgccaa cgctgtttcc
    26881 gtctccgcca ctacaatgaa atcacagatg tccagttgac gaacgatgat ttcctcaagc
    26941 tcttgcacga ggtgggagac agtgatgcct tagtggtcaa tgtcattgat atctttgatt
    27001 ttaatggctc tgtcatccca ggtttaccac gtttcgtctc gggcaatgat gtcctcttgg
    27061 taggaaataa aaaagatatc ctccctaagt cagttaagtc tggtaagatt agccagtggc
    27121 tcatgaaacg tgcccatgaa gaaggtcttc gtccagtcga tgtggtccta acttcagcac
    27181 aaaataaaca tgccattaag gaagtcattg acaagattga acactaccgt aagggccgcg
    27241 atgtctatgt ggtcggtgtg accaacgttg gaaaatcaac tctaatcaat gctattatcc
    27301 aagaaatcac gggtgatcag aatgtcatca ctacttcacg cttcccaggg acaaccttgg
    27361 acaaaataga gattccgctt gacgacggat cttatattta cgatacgccg ggaattatcc
    27421 accgccacca gatggctcac tacttgacgg ccaaaaacct caagtatgtc agtcctaaaa
    27481 aggaaatcaa gcctaagacc tatcagctta atcctgagca aaccctattt ttaggtggtt
    27541 tgggacgctt tgactttata gcaggagaaa agcaaggatt tactgctttc tttgataatg
    27601 aactcaaact ccatcgtagc aagcttgaag gagctagtgc tttctacgat aagcacctgg
    27661 gaactcttct gacaccacca aatagcaagg aaaaagaaga tttcccaagg ctagtccagc
    27721 atgtctttac cattaaagat aagacagacc tagtcatctc aggcctaggc tggattcgtg
    27781 taacaggcat agcaaaagtc gccgtctggg caccagaagg cgtcgccgtc gtcacacgaa
    27841 aagcaattat ttaagcacag aaaggaaagg gttgtctgaa tttgggcgag caaggcgagc
    27901 cccatagaga atacttttcg ctgtggtgta agttggtaca agtgattgta ccaactgcgg
    27961 aaaatttgag accttaggct caaattttag tcatgaaagt ccgaaggact ttgctgacgt
    28021 ccgtcaccac ttcagaaaag tataaaaaga aactctttta aagaaattat gtcattaaca
    28081 tcaaaacaac gtgccttcct caacagccag gcacacaccc tcaaacctat catccaaatc
    28141 gggaaaaatg gactcaacga ccaaatcaaa accagcgtcc gtcaagctct tgatgcgcgt
    28201 gaattaatca aggttactct cttacaaaac acagatgaaa acatccacga agtagctgaa
    28261 attttggaag aagaaatcgg tgtggataca gtccaaaaaa taggacgcat cttgattttg
    28321 tttaaacaat ctagcaagaa agaaaatcgc aagatttcta agaaagtcaa agaaatctaa
    28381 gaccgaaact ccaaataact gtttttatag agaaataaag gggactagcc tatgacaatc
    28441 gaactattga ctccctttac caaggtagag ttggagccag aaatcaagga gaaaaaacgc
    28501 aaacaagttg ggattttagg ggggaatttt aaccctgttc acaatgccca tctcattgtt
    28561 gcggatcaag tacggcaaca gttgggactg gatcaagttc tgctcatgcc tgaataccaa
    28621 cctcctcacg ttgataaaaa ggaaaccatc cctgaacacc atcgtctcaa gatgcttgag
    28681 ttggcaattg agggaattga cggcctagtc attgaaacca ttgagttgga gcgcaagggt
    28741 atttcctaca cctacgacac catgaagatt ttgacagaga agaatccaga tacggattat
    28801 tactttatca tcggtgccga catggttgac tatctgccta agtggtaccg aattgatgaa
    28861 ctggttgaca tggttcagtt tgtgggggtt cagcgtccac gctacaaggc agggacttcc
    28921 tatccagtta tctgggtgga cgtaccgctc atggatatct cgtccagcat ggtgcgtgcc
    28981 ttccttgccc aaggtcggaa acccaacttt ctcctacctc agcttgtgct agactatatc
    29041 gagaaggagg ggctctactg atgtcctatc aagactatat caactgctct cgtgaggcct
    29101 tgttggaaaa aatggcagag cttctacctg agaaacgtct aacccattgt ctaggtgtgg
    29161 agcgtgccgc tatggaatta gctcagcgct ttggtgtaga tgttgagaaa gcaagtctag
    29221 caggtcttct tcatgactat gctaaaaagt tgtcagatca ggaatttcta gacttgattg
    29281 accgttacca gctagaccct gacctcaaaa actggggcaa taatgtctgg catggtatgg
    29341 tcggaattta caaaattcag gaagatttgg atttgcatga ttcagaaatc ctgcgagcca
    29401 ttgaagtcca tacagtcggt gctggtcaga tgacagacct agataaggtt gtctatgtag
    29461 cagactatat cgagcacaat cgatcctttc ctggagtaga tgtggcgcgt gagattgcaa
    29521 gtctatcgct caataaggcg gtggcctacg aaacagctcg taccgtggag tatctagctc
    29581 atcagggatt ccccatctat ccccaaaccc ttgaaaccta taacgccttt gtgcactatt
    29641 tgaaagagga ctaaatgaag acggctttta taatcattga tgttcagaat gttttagtag
    29701 aaactgggtt ccagacaaaa agtctattgg aaaaaatttc ttatttacaa aaccaggcta
    29761 gaagcaagaa tattgaaatt atctatgttc aacatattga gaactctgaa gctcaaacat
    29821 cagaaggttg gcagttatct gcgcttttaa atcgaaaacc tgctgaaaag gtctttcaga
    29881 agaagtataa cagtattttc aaagaaactg gcttaaaaga atacttggat aaacagggga
    29941 ttgaaaaatt agttttatgt ggtatgcaga cagaatattg tgtggatacc tctgtcaagg
    30001 ttgcctttga atatggctat cagcttattg ttccagaagg tgctgtcaca acctttgatg
    30061 gggatgacat tccagcagaa acgattaatg aattttatga ggacatttgg gaggagcgct
    30121 ttgcagatgt cctagattac aaacatattt tctaaaaaga ggattaaatg aacgaaaaag
    30181 aattactaga actagtcgtg aaagcggctg atgagaaacg tgcggaggat atcctcgcac
    30241 ttgatgtaca agatttgact agtgtgacgg actactttgt catcactagc tcaatgaata
    30301 gccgtcagtt ggacgctatc gcagctaata tccgtgaaaa agtagctcaa gcaggcttta
    30361 aaggtagcca tgtcgaaggc gatgcagctg gaggctgggt cttactggac ctcggtgctg
    30421 ttgtcgtgca tatcttttca gaagaaatgc gtgcccatta taatctagag aagctatggc
    30481 atgaggcgaa ttcagtagat atttcagaag ctcttgctta gaagatgaac tcagttgtag
    30541 tcaactgggt ttctttgctt attttagaaa aattgataga aaggtaaagg gctagtggtg
    30601 tttaccatgg agctcttggt atcatgatta tggcgactta tgaaaccttt gcggcggtct
    30661 atgatgcggt catggacgat agtttatacg acaaatggac gaatttttct ctgcgtcatt
    30721 tgcctaagac caaggagaga aagaaactct tggaattggc ttgtgggaca ggaattcaat
    30781 cagtgcgctt ctctcaggct ggttttgatg tgactggact tgacttgagt gcggatatgt
    30841 tgaagattgc ggagaagaga gcaacttcag ccaagcaaaa gattgctttt atagaaggta
    30901 atatgctgaa tttgtccaag gcagggaaat acgattttgt cacgtgttat tcggactcta
    30961 tctgctatat gcaggatgag gtggaagtag gggacgtctt taaggacgtg tacaatgtgc
    31021 tgaatgaaga gggagttttc atctttgacg tgcactcgac ctaccagaca gatgaagtat
    31081 tccctggcta ttcctaccat gaaaatgcgg aagattttgc catgctttgg gatacatatg
    31141 aggacgaagt tcctcactcc atcgtgcatg agctgacttt ctttatcaag gaggctgacg
    31201 gttcctttag tcgccacgat gaagtacatg aggagaggac ctatgagatc ttgacctatg
    31261 atatcttgct ggaacaggct ggatttaagt ccttcaaact ctatgcagac tttgaggata
    31321 aggaaccaac agaaactagc acccgttggt tttttgtggc gcagaagtag gagaacatca
    31381 tgaccatcac aggtattatc gcagagttca atccttttca taatggccat aaatacctgc
    31441 tggatcaggc agagggactg aaaattgttg ccatgtcagg gaatttcatg cagcgtggag
    31501 agcctgctat tgtggataag tggacaaggg cccagatggc gctggaaaat ggcgcagact
    31561 tggtagtgga attgcccttt ttagtcagtg ttcaggcagc tgatttcttt ggtcaaggag
    31621 ctgtggatat cttggatcgc ttgggcattg atagtctagt ttttgggaca gaggaagttc
    31681 gagattatca gaaaatcgct gacttataca cagagaaagg tactgagatg gagaaatttg
    31741 tggaaaatct gcctgattcc ctttcctatc cccagaaaac ccaagctatg tggaaggaat
    31801 ttgctggtct tgatttttca ggtaataccc ccaatcatgt tcttgctctg gcctatgcaa
    31861 aggcggttgc aggacgaaat atcaagctgc atccgattca gcgtcagggg gcaggttacc
    31921 attctgtgaa taaagatgtg gactttgcct cggcgacagc cctccgtcaa catcagaagg
    31981 accaagattt cttagaacgc tttatgcctt ctgttgccct atttgagcag gccagtaagg
    32041 tgatctggga agactatttt cccttgctcc gctatcaaat cttgtcaaat cccgacctaa
    32101 ccaccatcta tcaggtcaat caagaaatgg ctgtgcgcat taaagaagct attaaaacag
    32161 cccagtctgt ggaagaattg gtcgagttag tgactaccaa acgttacacc aaggcgcgtg
    32221 tcagacgcct attgacctat attttgatgc aggctagaga aagtgacttg ccagaagcca
    32281 ttcatgtcct tggatttact gaaaaaggta ggcaacatct caagtctttg aaaggtcagg
    32341 tcagtctagt cagccgaatt ggcaaagaac cttgggatgc tatgactcaa aaggctgacc
    32401 agatttacca actaggaaag ccaagtatag cacaacagaa ttttggaaga gtgccgatta
    32461 gaatagaaac aaactaagtc taccgaaagg tggacttttt gagatttttt acgaataata
    32521 ctcttcgaaa atcaaattca aatcgcgtca acgtcgcctt gccgtactca agtacagcct
    32581 gcggctagtt tcctagtttg ctctttgatt ttcattgagt ataaatagat agaaaagaaa
    32641 atcttgtaca agttcctgac aatttctttc ttttcgtgta taatagtgga aaagagctaa
    32701 aacgaggtat ggttatggaa gcagtccttt actcaacatt ccgaaatcat ttaaaggact
    32761 acatgaagaa ggtaaatgat gaatttgagc ctttgacggt ggtcaataaa aatccagatg
    32821 aggacattgt agtcctttca aagagtgagt gggatagtat ccaagaaacc ctgagaattg
    32881 ctcaaaataa ggaactttct gataaggttt tgcgaggaat ggctcaagtt cgtgctggaa
    32941 gtactcaggt ccatgttatt gaggagtaag aaatgctgct caagtttaca gaagatgcct
    33001 gggcagatta ttgctactgg caaaaccaag ataaaaaaac actaaaaaga atcaataaat
    33061 taatcaagga tattcaacgc gatccattta caggaatagg aaaaccagag ccactcaaat
    33121 atgattacca aggagcctgg tcacggcgta ttgatgcaga aaatcgcttg atttatatga
    33181 tggatggaga tagcgtggct ttcttgtcct ttaaagatca ttactaagtc tactgcaaag
    33241 taggcttttt ctcaagtctc tactaaacta ctatttctaa acaacaagtt tattttggta
    33301 aatgtgttcc aaattcccca aaacatattc tattttaggt ttgtgaaaat cactttttta
    33361 tggtagaatg taaaagaatg tatgtcattc ggaataacaa taaaatgagg taaaaacatg
    33421 gaaatcatgt cgcttgcgat tgctgttttt gccgtcatca ttggtttagt cattggatat
    33481 gtcagcatct cagctaagat gaaatcatct caggaagctg cagagttgat gcttttaaat
    33541 gctgaacaag aagcaactaa tttacgtgga caagctgagc gtgaagcgga tttacttgtt
    33601 aatgaagcca aacgtgaaag caagtctctt aaaaaagaag cactattgga ggccaaagaa
    33661 gaagccagaa aataccgtga agaagtggac gctgaattca aatcagaacg tcaagaactc
    33721 aaacaaatcg aaagtcgttt gacagagaga gctactagcc ttgaccgtaa ggacgacaat
    33781 ttgacgagta aagaacaaac acttgaacaa aaagaacaaa gtatttctga tagagcgaaa
    33841 aaccttgatg cgcgtgaaga gcaattagag gaagtcgaaa gacaaaaaga agcagaacta
    33901 gagcgtattg gtgctctgtc tcaggcagaa gcacgagata ttatcttggc tcagacagag
    33961 gaaaacttga ccagggagat tgccagtcgc attcgcgaag ctgagcaaga ggtcaaggaa
    34021 cgttctgaca aaatggccaa ggacatcttg gttcaagcta tgcaacgtat cgctggtgaa
    34081 tatgtagcgg agtcaacaaa ctcaacggtt catctgccag acgatactat gaagggacgc
    34141 attattggtc gtgaaggtcg taacattcgt acctttgaaa gtttgacagg ggtcgatgtg
    34201 attatcgacg atacaccaga agtggtgacc ttgtcaggat ttgatccgat tcgtcgtgag
    34261 attgcccgta tgactatgga aatgttgctc aaagatggtc gtatacatcc agctcgtatc
    34321 gaagagttgg ttgagaaaaa ccgtcaagag attgacaata agattcgtga atacggtgag
    34381 gctgctgcct atgaaattgg tgcgccaaac cttcatccag acttgatgaa gattatggga
    34441 cgtttgcagt tccgtacttc atatggacaa aatgttttgc gccattcgat tgaggttgct
    34501 aagttggctg gtatcatggc gagcgaactt ggtgaaaatg cggctcttgc ccgtcgtgct
    34561 ggattccttc acgatatcgg gaaagccatt gaccatgagg ttgaaggtag ccacgttgaa
    34621 atcggtatgg aattggcccg taagtacaag gaacccccag ttgtggtgaa tacgattgct
    34681 agtcaccacg gagatgttga agctgagagc gtgatagcag ttatcgtcgc tgcagcagat
    34741 gccttgagcg cagcccgtcc aggtgctcgt agtgagtctc ttgaaagcta catcaagcgt
    34801 ctccatgatt tggaagaaat tgctaacggc tttgaaggag tgcaaactag ctttgccctt
    34861 caagcaggac gtgaaattcg tatcatggtc aatccaggaa aaatcaagga cgacaaagtc
    34921 acaatcttgg ctcacaaagt tcgtaagaaa attgaaaaca atctcgatta tccaggaaat
    34981 atcaaggtaa ccgtgattcg cgagcttcgt gcagtagatt atgctaaata aataagaaag
    35041 agcagttgaa aaattactgc ttttttgtta cactagatag aaagactgta aaggataatc
    35101 tggctttttg ccattattct agagaaatgt tatttcacag attgactaaa aggagacaca
    35161 atggcagacc gaggcttact aatcgttttt tctggtcctt caggggttgg aaaaggaacg
    35221 gttagaagag agatttttga gagttctgaa aaccaatttc aatattctgt atcgatgacg
    35281 acacgcgcac aacgtcctgg agaagtggac ggtgttgact acttcttccg tactcgtgaa
    35341 gaatttgaag agctgattcg tcaaggacag atgttggaat acgcagaata tgtcggcaac
    35401 tactatggaa ctcctctgac ctatgtcaat gaaaccttgg acaagggaat cgatgttttc
    35461 cttgaaattg aagttcaggg tgctcttcag gtcaagaaaa aggttccaga tgctgtcttt
    35521 atcttcctga caccaccaga tttggatgaa ttgcaagatc gcttggtagg tcgtggaaca
    35581 gatagtgcag aagtgattgc ccaacgaatc gaaaaggcca aggaagaaat tgccctcatg
    35641 cgtgagtatg attatgcgat tgtcaacgat caggtgcccc tagctgctga acgtgtcaaa
    35701 tgtgtgattg aagcagaaca cttctgtgtg gatcgtgtca ttggtcacta tcaggagatg
    35761 ttaccaaaat ctccaactac ccgataaaat ttagaaaata ggtacaagca aatgatgtta
    35821 aaaccctcta ttgatacctt gctcgacaag gttccttcaa aatattcact cgtaatcttg
    35881 gaagcaaaac gtgcccacga attggaagca ggtgccccag caactcaagg tttcaagtct
    35941 gaaaaatcaa ctcttcgcgc tttagaagaa atcgaatcag gaaacgttac aattcaccca
    36001 gatccagaag gaaaacgtga agcagtgcgt cgccgtatcg aagaagaaaa acgccgcaaa
    36061 gaagaagaag aaaagaaaat caaagagcaa attgctaaag aaaaagaaga tggtgaaaaa
    36121 atttaaggtt ggggggactc aatcttattt tttctattgc aagaatgtac tgacaaggag
    36181 gaggtgagaa gatggcccta gctaagatta tcgtagatgt gcccttgatg cagacggacc
    36241 agccctatag ttacaggatt ccggaggaat ttgagggaat gctggaagtt gggatgcggg
    36301 ttcatgtgcc ttttggtaag ggtaatcgcc tgattcaagg gattgttttt ggtttggagt
    36361 cccaatcaga tggagaagag atggagcaag atttaaaaga tattgcagag gtgctggatt
    36421 tttctcctgt tctcacgcca gaacaactct ggctggctga ggagttacgc aaatctgtct
    36481 tctcctacaa aatctctatc ctcaaggcca tgcttccggg atttctgaat tctagctatg
    36541 acaagattct ctatcctctg gaaggcttga gtcaggaaga acgagtgcgc ctgtttggtt
    36601 cagaagattc gctagccttt tcttctctgg atttaggtaa gcaagctgaa atgatgcgtt
    36661 tgactagaaa aggcctgctt ggtctggaat atcaggcagt cgatcaaaag aaggtcaaga
    36721 cccagtcttg gtatgaggtt gaccatgctc aattagaagg tgttgagatt tctacacgtg
    36781 ccaagaaaaa gttggaactg agagattatc tgctgtctca tccagagagc gcttccttgg
    36841 ctagcttgtt agagtcctac tcgcgagagc aagtcaactt ctttgtggat caaggtgctg
    36901 ttaccatagt ccaaaaggaa gttcgacgct cggctgctta ttttgaagga attgaagcaa
    36961 gtagaccttt ggagttaaat ccagaacaaa gacaggcgcg tgatgcggtt gtgagttcta
    37021 ttggcagttc tcaacctccc tttctacttc aagggattac aggaagtggg aagaccgagg
    37081 tttacttgca gattatccaa ggtgccctgg ataagggcaa gacagctatt ttgctggtac
    37141 ctgagatttc cttgactcct cagatgaccg agcgttttat agcacgtttt ggggacaagg
    37201 tagccattct tcactcagga ttatccaatg gcgaaaagta tgatgaatgg cgcaaggtgg
    37261 agcgtggcga tgcccaagtt gttgttggtg ccagatctgc tatctttgct cctctgaaaa
    37321 atctgggtgt catgattatt gatgaagagc atgaagcggc ttataagcag gacagcaatc
    37381 cccgttacca tgccagagag gtagctattt tacgggctca gtataatcaa gcaactctgg
    37441 tacttggatc tgcaacgccg agcttagaga gccgggcacg tgctggcaaa ggcgtctatc
    37501 aacacttacg tctaacccaa cgtgccaatc ctttggctac aatccctgag gttcaagtga
    37561 ttgactttcg agactatatc ggacaaaatg agacgtcaaa ctttacgcct cctttgctag
    37621 aggctatcca agaccgtctg gttaaaaaag agcaggtggt tctcatgctc aatcgccgtg
    37681 gttattctag ctttgtcatg tgtcgggagt gtgggacggt ggatacttgt cccaactgcg
    37741 atatttctct gaccttgcat atggatacca agactatgaa ctgccattat tgtggtttct
    37801 cgaaggatat tcctcaggtc tgtcctaact gtaagagcca cagtattcgt tactatggga
    37861 cgggaactca gaaggcttat gatgagctag cagaactctt tccccaagct cgcattttga
    37921 ggatggatgt ggatacgact cgaaagaaag gcagtcacca agccttgctt gaccagtttg
    37981 ggcgagggga agcggatatt ttacttggta ctcagatgat tgcaaagggt ttggattttc
    38041 ccaatgttac cctagtcgga gttctaaatg cggatacggc cttgaatctg cctgatttcc
    38101 gttcttctga gagaaccttc cagctcttga ctcaggtggc aggtcgagca ggtcgggctg
    38161 aaaaagcagg tcaagtcttg atacagtcct acaattcgca gcactatgct attcgatttg
    38221 ccaaggatca agattacgaa ggcttttatg cctatgaaat gggaatcaga cgacaactcg
    38281 gctatccacc ttactatttc acgattggta ttaccctttc tcacaagaaa gaagaagagg
    38341 ttttcaaacg tgcctatgaa gtcatgaaca ttttgcggtc aggcttgtca gagaccagtc
    38401 ccattctggg gccaacgcca aaaccgattg cccgtaccca caacctctat cattaccaga
    38461 ttttaattaa ataccgttta gaggatgagc tggggccgac cctcaaccag gttttagcct
    38521 tgactcaaga acgggaaaat agtgagctcc gtctcagcat tgaccatgag ccgcaacaat
    38581 ttttataaga aggagaagat atgacaaaac taatctttat ggggaccccc gacttttcag
    38641 caacagtctt aaaaggactt ttgacagata accgttacga aattctagcc gttgcgaccc
    38701 agccagaccg tgctgttggt cgtaaaaaag ttatccaaga aaccccagtc aagcaggctg
    38761 ccaaggaagc aggactatct atctaccaac ctgaaaaatt atctggaagt ccagagatgg
    38821 aagatcttat gaagctagga gcagatggaa ttgtgactgc tgcttttggg cagtttctcc
    38881 caagcaaact ccttgatagc atggactttg ctgtcaacgt tcatgcctcc ctccttccta
    38941 gacaccgtgg tggtgcgcct atccattatg ccttgattca aggggatgag gaagctggtg
    39001 tgaccatcat ggaaatggtt aaggaaatgg atgcaggaga tatgatttct cgtcgcagca
    39061 ttccgatcac agatgaggac aatgttggca ccttgtttga aaaattggcg ctagttggtc
    39121 gtgatttgct tttggacact ctgcctgcct atattgctgg tgatatcaaa cctgaaccgc
    39181 aggatacgag tcaggttacc ttctctccaa atataaagcc agaggaagaa aaactggact
    39241 ggaacaaaac caatcgtcaa ctctttaacc aaattcgtgg aatgaacccc tggcctgttg
    39301 cccatacttt ccttaagggc gaccgcttta agatttatga agccctacca gtagaaggtc
    39361 agggaaatcc aggtgagatt ctctctatct gcaagaaaga attgattgtc gcaacggctg
    39421 aaggggctct atccctcaaa caagtgcagc cagctggtaa gcctaagatg gacattgctt
    39481 ccttcctcaa cggagttgga cgtacattga ctgtaggaga acgatttggt gactaaagta
    39541 gaaacggcta gaagtttagc tctagcagtg ctagaggatg tttttgtgaa tcaagcatat
    39601 tcaaatattg ccttaaataa acacctcaag gggagtcagc tctctgcagc agacaagggc
    39661 ttagtgaccg agctagtcta tggaacggta gcccgtaaac tgactctgga atggtaccta
    39721 tcccacttta tcgaagacag agaccagtta gacagctggc tctatgtcct tcttctcatg
    39781 agtgcctacc aactccgcta tttggacaag attccagatc atgctgtggt caatgaagca
    39841 gtggaattag ccaaactccg taaaaaaggc agtgaaaaat tggtcaacgc tgtccttcgc
    39901 cgtatcttgc gtgaaggctg gccagatatt gctagcatca agcgaaaaaa caagcgtgac
    39961 tccattgcct attctctccc agtttggcta gttgccaaac tcaaggaaga atacggagag
    40021 gagagagcaa aagccatctt tgaaagcctg ttagtgcgaa acaaagccag tattcgtgta
    40081 acagacctaa gtcgaaaaga ggaaatccaa gccttgttgg aggcgaatga ttccctttta
    40141 gcaaccactg gtctggttaa ggagcaaggg cattttgcag ggcataattt gtttgcggat
    40201 ggagccatta ccatccaaga cgagtccagt cagctggttg ctccgacgct tgatttacaa
    40261 ggtgatgagc gagtgcttga tgcctgtgcg gctccaggtg ggaaaacagc ccatatagcc
    40321 tcttatctta cgacaggtca ggttactgct ctggacttgt acgaccacaa gttggattta
    40381 attcaagaaa atgcccaacg tctgggaatt gaagatcggg ttcaaactca aaaattagat
    40441 gccagaaagg tgcatgagtt ttttgaccag gattcctttg ataagatttt ggtggatgct
    40501 ccttgttcag gaatcggtct tttgcgccga aaaccagata tcaaatacaa taaagaaacg
    40561 gcagatttcg cgtccttgca ggaaattcag ttagaaatat taggtagtgt ttgtcaaata
    40621 ctaggcaaag gtggtataat aacttatagc acctgcacta tcgtctcaga ggagaatttt
    40681 caagtcgtta aggccttttt agagagtcat cccgagttcg agcaggtaaa actagaacat
    40741 gaatgtaagg atatcatgaa agacggctgt atcctcatta cacctgaatt gtatggaagt
    40801 gatggattct tcatcagtca atttcgcaag atatcggatt aggaaggaac tgacacatgg
    40861 aaatttcatt attaacagat gttggtcaga aacgaacaaa taaccaagac tatgtcaacc
    40921 actatgtcaa tagagctgga cgtaccatga ttattttagc tgatgggatg ggaggtcatc
    40981 gcgcagggaa tatcgctagt gaaatggcgg tcacagacct gggtgtagct tgggttgata
    41041 cccagatcga tacagtcaat gaagtgcgtg aatggttcgc ccattaccta gaaattgaaa
    41101 atcaaaagat tcaccagctt ggtcaggatg aagcttacag aggcatggga actactttgg
    41161 aagtccttgc tattattgat aatcaggcta tctatgctca tattggtgat tcgcgtatcg
    41221 gcttgattcg tggagaagaa taccatcagt tgacgagcga tcattccttg gttaatgaat
    41281 tgctcaaggc tggtcaattg acaccagaag aggcagaagc tcatccgcaa aaaaatatta
    41341 tcacccagtc tattgggcaa aaagatgaaa ttcagcctga ttttgggaca gttatccttg
    41401 agtcaggtga ctatctcttg ctcaatagtg acggcttgac caacatgatt tcaggcagtg
    41461 agattcgtga tattgtaacc agtgatattc ctttagcaga taaaacggag acacttgttc
    41521 gttttgctaa caatgcagga ggtttagaca acattacggt tgcccttgtt tctatgaacg
    41581 aggaggatgc agaatgatcc aaatcggcaa gatttttgcc ggacgctatc ggattgtcaa
    41641 acagattggt cgaggaggta tggcggatgt ctacctagcc aaagacttaa tcttagatgg
    41701 ggaagaagtg gcagtgaagg ttctgaggac caactaccag acggacccga tagctgtagc
    41761 tcgttttcag cgtgaagcga gagctatggc agatctagac catcctcata tcgttcggat
    41821 aacagatatt ggtgaggaag acggtcaaca gtatcttgca atggagtatg ttgctggact
    41881 agacctcaaa cgctatatca aggaacatta tcctctttct aatgaagaag cagtccgtat
    41941 catgggacaa attctcttgg ctatgcgctt ggcccatact cgaggaattg ttcacaggga
    42001 cttgaaacct caaaatatcc ttttgacacc agatgggact gccaaggtca cagactttgg
    42061 gattgctgta gcctttgcag agacaagtct gacccagact aactcgatgt tgggctcagt
    42121 tcattacttg tcaccagagc aggcgcgtgg ttcgaaggcg actgtgcaga gtgatatcta
    42181 tgccatgggg attattttct atgagatgtt gacaggccat atcccttatg acggggatag
    42241 cgcggtgacc attgccctcc agcatttcca gaaacccctg ccgtccgtta ttgcagaaaa
    42301 tccatctgta cctcaggctt tagaaaatgt tattatcaag gcaactgcta aaaagttgac
    42361 caatcgctac cgctcggttt cagagatgta tgtggacttg tctagtagct tgtcctacaa
    42421 tcgtagaaat gaaagtaagt taatctttga tgaaacgagc aaggcagata ccaagacctt
    42481 gccgaaggtt tctcagagta ccttgacatc tattcctaag gttcaagcgc agacagaaca
    42541 caaatcaatc aaaaacccaa gccaggctgt gacagaggaa acttaccaac cacaagcacc
    42601 gaaaaaacat agatttaaga tgcgttacct gattttgttg gccagccttg tattggtggc
    42661 agcttctctt atttggatac tatccagaac tcctgcaacc attgccattc cagatgtggc
    42721 aggtcagaca gttgcagagg ccaaggcaac gctcaaaaaa gccaattttg agattggtga
    42781 ggagaagaca gaggctagtg aaaaggtgga agaagggcgg attatccgta cagatcctgg
    42841 cgctggaact ggtcgaaaag aaggaacgaa aatcaatttg gttgtctcat caggcaagca
    42901 atctttccaa attagtaatt atgtcggtcg gaaatcctct gatgtcattg cggaattaaa
    42961 agagaaaaaa gttccagata atttgattaa aattgaggaa gaagagtcga atgagagtga
    43021 ggctggaacg gtcctgaagc aaagtctacc agaaggtacg acctatgact tgagcaaggc
    43081 aactcaaatt gttttgacag tagctaaaaa agctacgacg attcaattag ggaactatat
    43141 tggacggaac tctacagaag taatctcaga actcaagcag aagaaggttc ctgagaattt
    43201 gattaagata gaggaagaag agtccagcga aagcgaacca ggaacgatta tgaaacaaag
    43261 tccaggtgcc ggaacgactt atgatgtgag taaacctact caaattgtct tgacagtagc
    43321 taaaaaagtt acaagtgttg ccatgccgag ttacattggt tccagcttgg agtttactaa
    43381 gaacaatttg attcaaattg ttgggattaa ggaagctaat atagaagttg tagaagtgac
    43441 gacagcgcct gcaggtagtg cagaaggcat ggttgttgaa caaagtccta gagcaggtga
    43501 aaaggtagac ctcaataaga ctagagtcaa gatttcaatc tacaaaccta aaacaacttc
    43561 agctactcct taaaagcaga tggataatca aaatgagtaa tcaatctttg tcatgatttc
    43621 atggcaaaga ttttttttga gtccagattt gtgatagaat agagggagtt gataaaagga
    43681 ggaaagcatg gaagaatcaa aagaattaaa tgccgtcatt gatgtgatta tgctagcggg
    43741 gactattctc cttaaaagtg gctcagaaat ccatcgtgta gaagatacca tgattcgaat
    43801 cgcgcattcg caggggattg tggattgcaa tgtccttgcc atgcctgccg ctatcttttt
    43861 ctctattgaa aataccaata tttcgcgcat gaagcgcgtg acctcctctt cttataacat
    43921 cgaaaaagtc tgcgatgtga accagatttc tcgtcagcta gttggggggc agattgactt
    43981 agaaacagcc tttaagcaat tgacggcctt gcaagctcaa ccccttccct atactaagtt
    44041 gcaggtaact ctggctgcga cctttagtgc tcctttcttt tcagttatgt ttagcggaaa
    44101 tatctacgac gcacttgggg caggagtggc gaccttattt ggttttgcct tttccctcta
    44161 tgtggaaaaa tttatccgaa ttccctttgt gacagccttt gctggagcct ttgtctttgg
    44221 gataattgcc cagttttggg ctcgctacac aggttttcct tcaacggcag atttgattat
    44281 agctggtgcg gtcatgccgt ttgtaccagg tattgccttg accaatgcgg tccgtgatat
    44341 tatgaccaac cacataaact ctggtatgag taagatgttt gaatccctgc tcattaccct
    44401 cgctttaggg gcaggaactt ctgtcgcctt ggtattgatg aactaatatg acactaacaa
    44461 cctttttatt acaagcagta gcaagttttc ttgccattat cactttttta atcgtactca
    44521 atgtgcaacg gtctatgctc ttacctggag ggattttggg catgactgtc tggctaatct
    44581 atctcttgct caaggaaccg accaatgtca ttgtagctac cttcattgca gccattattg
    44641 gttcttgtgt cagccagatt ttaagtattc tttataagac acctgctgtg gtctttatct
    44701 tggccatttt ggcaccgctg gttccaggtt atctctccta ccgaacaact gccttttttg
    44761 tgacagggga ctataataaa gcactggcaa gtgcgacctt ggttgtcatg ttggctttgg
    44821 taatctctat tggaatggct agcggaacag tgattctcag actgtatcat tatataaaaa
    44881 cacatcgagt atcgtagact ttacagaaat aaaagaattt tctgaaaaat gagataaata
    44941 aattgacaac gctttctata tgtgcgagaa taccgcactt atgaagaaat tgcggctgat
    45001 tttggtatcc acgaaagcaa cttaatccgt cggagccaat gggttgaagt aactcttgtt
    45061 caaagtggtg ttacgatttc aaaaactcat cttagtgctg agaatacggt gattgtggat
    45121 gcaacagagg taaaaataaa tcgtcctaaa aaaatcaact agccaattat tctggtaaaa
    45181 tagaaatgtc attctatgga acctcaagcg attgtcacaa gtcaagggag aattgtttct
    45241 ttggatatcg ctgtgaacta ttgtcatgat atgaagttgt tcaaaatgag tcgcagaaat
    45301 atcggacaag ctggaaaaat cttggctgac agtggttatc aaggacccat gaagatatat
    45361 cctcaagcac aaactccacg taaatccagc aaactcaagc cgctaatagc tgaagataaa
    45421 gcttataacc atgcgctatc caaggataga agcaaggttg agaacatctt tgccaaagta
    45481 aaaacgttta aaatgttttc aacaacctat cgaaatcatc gtaaacgctt cggattacga
    45541 atgaatttga ttgctggcat tatcaattat gaactaggat tctagttttg caggaagtct
    45601 actattttcc ttattgtctg taagtctact gaccttgttg tttatcccag tcatggtttc
    45661 tagttcgggc tcagagtttc aaagtggatg gcaagagcat caattgattg ctgagaaggt
    45721 tagtaaaaca cttgacaaga catttgataa ggatgtcaga gaaattccga ccagtcagtt
    45781 ttatcaaaaa tttgtagatg agatgggaag gacttactca ggaaatttga tcctccagga
    45841 gctgataact gtgaatggag cttataaagc tacttatatc ggtgaactct ctagcaacta
    45901 atcattcttt aaaatgatga ccaataagag gcttgatttg gtgaatcaag tcttttttct
    45961 ctcttttact gccatttgtg ataaaatagt atagaacgat tttttacatg aatgataaaa
    46021 cagaggtaaa tatgacaatc ggtattgata agattggttt tgcgaccagt caatatgtct
    46081 tgaaattaca agacttagca gaagcgaggg gaattgaccc tgaaaaatta agtaaaggac
    46141 tcttactcaa ggaattgagt attgcgcccc taactgagga tatcgtgacc ttggcggcca
    46201 gtgctagtga ctctatttta actgagcaag aaagacaaga agttgacatg gtcattgtgg
    46261 cgaccgagtc aggaattgac cagagtaagg ctgcggccgt ctttgtgcat ggcttgctgg
    46321 gcatccagcc ctttgctcgt agtttcgaga ttaaagaagc ctgttatggg gcgacagctg
    46381 ccctccatta tgccaaattg catgtggaaa attctccgga gtccaaggta ttggtcattg
    46441 ccagtgatat tgccaaatat ggtattgaaa ctccgggaga accaactcaa ggtgctggaa
    46501 gtgtagctat gttgattaca caaaatccac gcatgatggc ctttaataat gacaatgtag
    46561 ctcagacccg tgacatcatg gatttctggc gaccaaatta ctcgacaact ccttatgtaa
    46621 atggtgttta ttctacccaa caatacttgg atagtttgaa aacgacttgg cttgaatatc
    46681 aaaaacgcta ccagcttact ttggatgatt ttgctgctgt ttgtttccac ttgccttatc
    46741 ctaaattagc gctaaaaggc ttgaaaaaaa tcatggataa gagcctgcct caagagaaaa
    46801 aagacctctt acaaaagcat tttgaccagt ctattctcta cagtcaaaag gtggggaaca
    46861 tctacacagg ttcacttttc cttggacttt tgtctctctt ggaaaataca gatagcttga
    46921 aagctgggga taaaatcgcc ctttatagtt acggaagtgg agctgtggct gagttcttca
    46981 gtggtgaatt ggttgaagga tatgaagctt atttggataa agaccgtttg aacaagctca
    47041 accaacgaac tgccctatcc gttgcagact atgaaaaggt cttttttgag gaagtaaact
    47101 tggatgaaac aaactctgcc cagtttgctg gctatgaaaa tcaagatttt gccttggttg
    47161 aaattcttga ccaccaacgc cgttatagca aggttgaaaa ataatgaaga taagttggaa
    47221 tggattttct aaaaaatcat accaagagcg cctcgagctg ttaaaagctc aggcgctcct
    47281 tagtcctgag agacaagcta gtctggagaa ggatgaacag atgagtgtga ctgtggcaga
    47341 ccagctgagt gagaatgtgg tgggaacttt ttctctgcct tattcgctgg ttccggaggt
    47401 acttgtcaac gatcaggaat acaccgttcc ctatgtgaca gaagaaccct ctgtggttgc
    47461 ggcggccagc tatgccatca aaatcatcaa gcgtacaggt ggttttactg cacaagtcca
    47521 tcagcgacag atgattgggc aggtagccct ttatcaagtt gctaatccta aactagcgca
    47581 agagaagatt gccagcaaga aagcggagct cttggagctt gccaatcaag cctatccttc
    47641 tatcgttaaa cgtggaggtg gggcgcgtga tctgcatgtc gagcagataa aaggcgaacc
    47701 agactttctc gttgtttata ttcatgtcga tacccaggaa gccatgggtg ccaatatgct
    47761 caacaccatg ctggaagcct tgaaaccagt cttagaagaa ctcagtcagg gacagagtct
    47821 catgggaatc ctgtccaact acgcgactga ttctctggtg actgcaagct gtcgcatcgc
    47881 ctttcgctac ttgagccgcc aaaaggatca aggacgagag attgcggaga aaattgcgtt
    47941 ggctagtcag tttgcgcagg ctgatcctta ccgagctgct actcataata aaggaatttt
    48001 taatggtatt gatgcgattt tgattgccac tggtaatgac tggcgtgcca tcgaagctgg
    48061 ggcccatgcc tttgccagtc gagatggacg ctatcaaggt cttagctgct ggacgctgga
    48121 ccttgaaaga gaagaattgg tcggtgagat gaccctgccc atgcctgtag cgactaaggg
    48181 tggctctatc ggcctcaacc cacgtgtagc tctcagtcat gatctactag gaaatccttc
    48241 tgccagagaa ttagcccaga ttatcgtgtc catcggtctt gctcaaaatt ttgcagccct
    48301 caaagccttg gtaagtacgg gcatccagca aggccacatg aaactacagg ccaaatctct
    48361 agctctccta gctggggcta gtgaatctga agttgctccc ctagtagagc gcctcatctc
    48421 agataaaacc tttaacctag agacagccca gcgctatctc gaaaatttaa gatcataaaa
    48481 actcagacga atcggtctga gttttcttgt gtttaaatac tttttcctgg taatagcgta
    48541 actggtaaga agtaaccagt tgtggcgact tccttgcctt caatcttttg caagagaaga
    48601 tcaatagtga gacaagcaat ctcttccaaa ggttgcttga tagtagccaa ttgagggtag
    48661 taattttcga taaagtaggt cccatcatag ccgatgacct tgagctcttt tgggacagaa
    48721 atgcccaatt cttgagcgat tttaatgacc agaatagctg tcaaatcatc cgaagcaaaa
    48781 atggcatctg gtttttcccg ggtcaagata ttcttgattt ccatttcttt tctgacggga
    48841 gaaaagtcac tggaaacatt gataatagga gcttttggga gtacggatgc aaaaccagcg
    48901 tggcgcagtc cggttggcga attagaattg tcattccctg taatcatgat gatagactgg
    48961 gcacctgtct tgaccaaggt ttgggcagca agaaccccac cagcatagtt gtcagaggag
    49021 acgacaggga tgtctggcga taggtttcgg tcaaaggaaa taatcggcgc tgtcacacga
    49081 ttgtagtctt cgattcctag gttgtgacta ccagaaatga tgccgtccac ctgattggct
    49141 tccaacattt cgatgtattc gcgttccttc tcagaatcat gttcactgtt gcagatgatg
    49201 gtcttgtaac catttttgaa gagttggtgt tccaatttat caatcaattc tgcatagaaa
    49261 acattggaaa tattggggaa aatcaagccg attaacttag ctgattttcc ttgcagacta
    49321 cgagccaggt tgttgggttt atagcccaat tctctcatgg cttcattgac tttttggatg
    49381 gttttctcag atagataccc ttttttattg ataacccgag aaacggtagt aggactgacg
    49441 cctgcaagtt tggcgacatc agttagtttt gcgaccataa tctaattcat agtaagttcc
    49501 agttgggttt ccagatttga tcaggatacc attttggtcc gcatgtggga agacacgacc
    49561 agaaaatact ttttctcctt tattgatgaa aatttcaaag acagagttat cgatgaagat
    49621 tgtagcagta gtagcctgat tctcgatagg gcaagaacga gttgtcccaa attcttgggc
    49681 atactgctct ccagcctggc tacgatccac tgtcacttga ccgtttacaa ggtcaaagtt
    49741 gattgaaagt cccttacctt ctttatcagc aagtaagaca atctcgctct ggctattagc
    49801 ttccaagttg agttcaagtt cgtaagtgtt cttggtttgg gaacggtttg agaaggcttc
    49861 ttcagaagca cgaaggtcct taatagcagc gactggatac tggtagagct tgtcgtcttt
    49921 gatagtgagt tccttgacca aagagaaggt tccttggtgg tcaaaacggt cagatgggta
    49981 agaaacatct ggcaaaccaa gccagctaac tgctagagca cgcccatcag gagcgttgaa
    50041 ggcttgagtt gcataggctt cgaaaccgta atccatgttt tgaagttgag acacatctac
    50101 cattttggca tttttagggt caaaggaagc cccaatctta tacatatttg gaaagatatt
    50161 atcgtagtct agaactttct tatccaatcc ttgtggacag tagagaagga caggatgttc
    50221 ctctacaaag accagattag gacattccat catgtaggca gtacggtcgt tagcaaagtc
    50281 aaggtcgcca actgcttgcc agtttgtgta gtcgttattg acagccttgt agagacggac
    50341 gaagcctttt ttctccaagt cctgtccacc gacgacagca tagtattgac ctttaaagtt
    50401 aaaaatttgt ggatcgcgga agtggtcagt agagtctgct ggctggtcaa tcaagatctt
    50461 gtcaatcttt gtaatcttac cctccttgtc catcaaagca ccgatctggt atgggtgacg
    50521 gatccagttt tcatcgcgaa catttcctgt ataaaatagg aataagttat cgccaaattg
    50581 catggcagaa ccagagtagg caccgtggct atctaatgga gtatctggta aaactttgat
    50641 tccagtttct ttaaagtgaa ccaaatcatc actttctagc tgtgcccaag atttcaaacc
    50701 gtgggctgca ccaaaaggaa aattctggta aaagaggatc cacttgccat caaagtaaga
    50761 aaagccattt gggtcgttga gaagtcctgt ttttggctca acatggtaat gagtatgcca
    50821 tggagattgt gccatatttt cctttatatg ttgaatttct tcttgcgtcc aatcttgata
    50881 aagtctgtaa cgacgctcag ttgtccattc cattcattcc tccaaaaatc ttatcacttt
    50941 taatagtaac tgttttcgat aaaaaatgca agccttttat attaaaaaag agaaaaaact
    51001 gtcaaacgat taccataaaa taaatacagg aaatcaatca aatttttacg aaaatgtgaa
    51061 agataatgaa ataaaagact ttttaaccaa ggtttcaaac ttatttttca agaaattcct
    51121 gatgaaacag tcaaaaacaa tcaatctaaa gcttgcccac taagtagata gaatattttt
    51181 tctgcaaaac gcttgacata tttttaaaac atgataaaat aatagtcgta agggcgaata
    51241 aaatcgcttt caaacaagaa caaaatgtta tataaggaga tttttgcaaa tgaacaatca
    51301 ggaaattgca aaaaaagtca tcgatgcctt gggcggacgt gaaaatgtca atagtgttgc
    51361 ccactgtgcg actcgtctac gtgtcatggt caaagatgaa gagaaaatca ataaagaagt
    51421 gattgagaac ttggaaaaag ttcaaggtgc tttctttaac tcagggcaat accaaattat
    51481 ctttggtaca ggtacagtta acaaaatgta cgatgaagtt gttgtacttg gcttaccaac
    51541 atcatctaag gatgacatga aagcagaagt tgctaaacaa gggaactggt tccaacgtgc
    51601 tatccgtact ttcggtgatg ttttcgttcc aatcatccca gttatcgtag cgacaggtct
    51661 cttcatgggt gtgcgtggtc ttttcaacgc tcttgaaatg ccacttccag gtgactttgc
    51721 aacttacaca caaatcttga cagatacagc cttcatcatc ttgccaggtt tggttgtgtg
    51781 gtcaaccttc cgtgtatttg gtggaaatcc tgccgttggt atcgttcttg gtatgatgct
    51841 tgtctctggc tcacttccaa acgcttgggc agttgctcaa ggtggtgaag taacagcgat
    51901 gaacttcttt ggtttcatcc ctgttgttgg tttgcaaggt tccgttcttc cagccttcat
    51961 catcggggtt gtcggagcta aatttgaaaa agctgtccgc aaggttgttc cagatgtcat
    52021 tgacctcttg gtaacaccat tcgtgacact tttggtcatg tctatccttg gactctttgt
    52081 cattggacca gttttccacg ttgttgaaaa ctacatcctt attgctacaa aagcgattct
    52141 tagcattcca tttggtcttg gtggtttctt gattggtggg gttcaccaat tgatcgtcgt
    52201 gtcaggtgtg caccacatct tcaacttgct tgaagtgcaa ttacttgctg ctgaccatgc
    52261 taacccattc aacgctatca tcacagctgc tatgacagct caaggtgctg ctactgttgc
    52321 ggttggtgtt aaaacaaaaa atccaaaact gaaaacactt gctttcccgg ctgctctttc
    52381 tgccttccta ggtattacag agcctgctat cttcggggtg aacttgcgct tccgtaaacc
    52441 attcttcctt tcattgattg ctggtgcaat cggtggtgga ttggcttcta tccttggact
    52501 tgctggtact ggtaatggta tcaccatcat ccctggtaca atgctttatg ttggtaacgg
    52561 acaacttcca caataccttc ttatggtagc tgtatcattt gcccttggtt ttgctcttac
    52621 ttacatgttt ggttacgaag atgaagtaga cgcaactgca gctgcaaaac aagctgaagt
    52681 ggctgaagaa aaagaagaag ttgcgccagc agctcttcaa aatgaaacac ttgtaactcc
    52741 tatcgttggt gatgttgtcg ctcttgctga tgtcaatgac ccagtcttct caagtggagc
    52801 tatgggacaa ggtatcgctg tgaaaccaag ccaaggcgtg gtctatgcac cagctgatgc
    52861 tgaagtttca attgcctttc caacagggca cgcttttggt ttgaaaacaa gaaatggtgc
    52921 tgaagttttg attcacgttg gtattgacac tgtatctatg aacggtgacg gttttgaagc
    52981 aaaagttgct caaggtaata aggtgaaagc tggcgatgtt cttggaacat ttgactcaaa
    53041 caaaatcgct gcagctggac ttgatgatac aacaatggtt atcgttacaa atacagctga
    53101 ctacgcttca gtagctccag tcgcaacagg ttcagttgcg aagggggatg ctgtgatcga
    53161 agtgaaaatc taatcaatcc tctctaataa aaacgaacaa atgacatgtt tgttcgtttt
    53221 tattagatag taagatttac agaggaaaat ctaaaaaata gagacattta gactttcgaa
    53281 gtatgctata ataaagaaaa taaaaacaag aggtttatca tgacaaaatt atatggaagc
    53341 ttggaagcgg gcggtacaaa gtttgtctgt gctgtcggtg atgaaaactt taacgttgta
    53401 gaaaaaacac aatttccaac aacaactcca atcgaaacaa tcgataaaac cattgagttc
    53461 ttctcaaaat tcgataacct tgctggtctt gcagttggtt catttgggcc gattgatatt
    53521 gacaaaaact caaaaactta tggctttatc acgacgactc caaaaccaaa ctgggcaaat
    53581 gtggacttgc ttggtgccct tcgtcgcgcc ctaaacgtgc caatgtactt cacaacagac
    53641 gtaaacagct ctgcttacgg tgaagtggtt gcccgtaaca atgctggtgg tcgtatcgaa
    53701 aacttggttt actacacaat cggtacaggt atcggtgcgg gcgtcatcca acgtggtgag
    53761 tttatcggtg gtgtgggtca ccctgaaatg ggtcattatt atgttgctag acacccaatg
    53821 gatattgaaa aagagtttaa gggtgtttgt cctttccata agggatgtct agaaggttat
    53881 gcagctggtc caagtttgga agctcgtaca ggtgtacgtg gggaaactat tgaactcaac
    53941 aaccctgttt gggatgttca agcctactat atcgctcaag ctgcggttaa tgcgacagtg
    54001 actttccgcc cagacgtgat tgtctttggt ggaggggtca tggctcaaca acatatgctg
    54061 gaccgtgtcc gtgagaaatt tacatctctt cttaatggtt acctaccagt accagatgtg
    54121 cgtgactata tcgtgacgcc agcagtcgca ggaaatggtt ctgccacact tgggaacttt
    54181 gttcttgcaa aagaagtttc aaaataaagc acaaaatccg cttgggaaac caaacggatt
    54241 ttgtggttga aaacaatatt tttgagcctt tccttaagtg attacggacg gtagcgactt
    54301 tcttcgaaat tccataccta aactttgaga cactaggctc aaagtttccg aatacctgaa
    54361 accattagat ttcaggtgtt tctatcacgg cggaaaggct aggtaagtcc tcgcctcact
    54421 atcgaaaaat atgcatgatt tccataccaa agtatattta gtatcaagct atagttaatc
    54481 tacgctttaa aaatccactt gggaaaccaa acggattttt tacgtgtcaa agcatttgcc
    54541 agaaaaagtc aataatatag gtcaaaccgt aggtataaac cacgagggta aagggtttgg
    54601 tcagaatgat gatggtcatg tagcgcttga aactcatctt ggtcagggca gccagcatac
    54661 agagaaagtc agctgggcta atgggccaaa tcatcataaa aataaagaag cggtcaaaac
    54721 gattgccctt atctagccag ccgatgtact tgtcgtaggt gcgcttgctg acgacagact
    54781 ggacaaaggc agctccgtat aggcgcacta gataaaagat aatggcacag ccaatcacga
    54841 tgccgatata gttgtagata gtcccgatga tgtgcccgta gataaagacc ccagccaccg
    54901 aggtcaaggc ccctggaatg atagggacga cagtctgtaa aatctgtaaa aagataaaga
    54961 gaggtggacc ccagatgcct gcctgctgga taaaggcaga gagggtttcc ttggattgta
    55021 aaatcccagc ctgataagcc caaatacaga aaatcaaact cccaacccca ccgacaatcg
    55081 atgagatatt gataactcgc tgcagaaggg gagaaacagc tttcatttgt ttatcctgtg
    55141 acatgtaaac tcctcataga tagtatattt ctactatacc atattttgga ggagaaaggg
    55201 ggaatgagtc ttttttgata aggaatagaa agtaaatagc ccttcgagac ttagaatagg
    55261 tctgtcaact aaaggttata tgcattctag gtttcgaata atcgcaattc catgaattta
    55321 aaagcattct aagtttcgaa tagcttatct gagataattt tgaggcattc gcgctttcga
    55381 atagtcattt tccctaaagt ttagatgtat tctgaagcta gaaagactaa aatctaaaag
    55441 tagtaagagt ctctctctga tggacgtaat ttatggctag tatgaatcct ttgaattgtt
    55501 agttaatttt aatattaatc agttctgaaa taattactaa atatagttag atggtgaatt
    55561 aattattgct aaatttcaag ttcaagttag tcatccagaa gtcttctctg ggggacttgt
    55621 agttcaagca ttttttagga tagttgttaa tccacttttc gatgaatgcg acttcctttg
    55681 tagtcgtttt cttagttccc tgaggtaacc atctatgaat gaacttgttg tgatttttat
    55741 tagatcctat agtggtgtgc ataatagata taatagattg aaactagaat agtacgcatc
    55801 tacttctaaa acattgttag aaatcgattt gactgtcccg atctatttgt cctgttttta
    55861 tttcattttg ctatataatc cttagaaaac atatgggaca agcggttgaa ttccgttccg
    55921 tccattagta gataaaggat tactccttct tgaaatgaca gatgaacttg tttcttataa
    55981 aaatgttgtc tgaaactatt cgcttttttc cagaagtttt agaggaagaa aactttatga
    56041 ggaaaaagga gttactcaaa taacaattca ggattaaaaa tagacagttg aggagcggaa
    56101 ggtataaatt aagtttgctg ctgtataatg gatttatcac taatactctt cgaaaatctc
    56161 ttcaaaccac gtcagcttcg ccttgccgta gatatagtta ctgacttcgt cagttctatc
    56221 cacaacctca aaacagtgtt ttgagctgac ttcgtcagtt ttatctgcaa cctcaaagct
    56281 gtactttgag cagtctacgg ctagcttcct agtttgctct ttgattttca ttgagtataa
    56341 aagtgctcca ggccatattt tacacagcaa tagtcttcta aaaatgaaca aaaaacattg
    56401 taaaggctat caaaaaggag tataatgagt gcaagaaatt tcggaggtga aagatgctag
    56461 aagtaagaag tctagagaaa agttttggat ccaagcaagt tttgtttggt attgactttc
    56521 aagcgcgacc aggtcgtatt ttgggactag tcggaaaaaa tggtgctgga aaaacaacga
    56581 ttttccatag tattttaaaa ttcctagaat atcagggaga aatcggtctg gatggtcagg
    56641 atattcgtca ggagacctat gctcggattg gttatctgcc tgaagaacgc agtctcatgc
    56701 ctaaattgac agttcttgaa caagttcgct acttggcgac tctaaaaggc atggatgcca
    56761 aagaagtcaa agaaaaactc cctcaatgga tgaagaggtt ggaagtgaaa ggaaagctgg
    56821 cagataaaat caagagtttg tcaaaaggaa atcagcagaa gattcagctc attattactc
    56881 tgattcatga accagacctg attatcttgg atgagccttt tagtggattg gacccagtta
    56941 atacagaatt gctcaaacaa gtcatttttc aggaaaaaga gcgcggagca accattatct
    57001 tttctgacca tgtcatgacc aatgttgagg aactttgtga cgatattctg atgatccgag
    57061 atggccgtgt ggtcttgcac ggaccagttc aggatgtccg caatcaatac gggaaaacac
    57121 gtctctttgt ttcaagtgaa cgaagcaagg aagaattgga aaatcttcct catgtcaaac
    57181 aggtgagctt gaccaaacaa ggcagttgga aattgatttt ggaggatgag agcgctggaa
    57241 gggaactctt cccaatcttg actcaaggtc aatatatcgc aacatttgac caacaagcgc
    57301 caactatcga tgaaatcttt aaactagaat caggagtgga agtatgagaa atatgtgggt
    57361 tgtaatcaag gaaacctatc ttcgacatgt cgagtcatgg agtttcttct ttatggtgat
    57421 ttcgccgttc ctctttttag gaatctctgt aggaattggg catctccaag gttcttctat
    57481 ggctaaaaat aataaagtgg cagtagtgac aacagtgcca tctgtagcag aaggactgaa
    57541 gaatgtaaat ggtgttaact tcgactataa agatgaagca agtgccaaag aagcaattaa
    57601 agaagaaaaa ttaaaaggtt atttgaccat tgatcaagaa gatagtgttc taaaggcagt
    57661 ttatcatggc gaaacatcgc ttgaaaatgg aattaaattt gaggttacag gtacactcaa
    57721 tgaactgcaa aatcagctta atcgttcaac tgcttccttg tctcaagagc aggaaaaacg
    57781 cttagcgcag acaattcaat tcacagaaaa gattgatgaa gccaaggaaa ataaaaagtt
    57841 tattcaaaca attgcagcag gtgccttagg attctttctt tatatgattc tgattaccta
    57901 tgcgggtgta acagctcagg aagttgccag tgaaaaaggc accaaaatta tggaagtcgt
    57961 tttttctagc ataagggcaa gtcactattt ctatgcgcgg atgatggctc tgtttctagt
    58021 gattttaacg catattggga tctatgttgt aggtggtctg gctgccgttt tgctctttaa
    58081 agatttgcca ttcttggctc agtctggtat tttggttcac ttgggagatg ctatctcact
    58141 gaataccctg ctctttattt tgatcagtct tttcatgtac gtagtcttgg cagccttcct
    58201 aggatctatg gtttctcgtc ctgaggactc agggaaagcc ttgtcgcctt tgatgatttt
    58261 gattatgggt ggtttttttg gagtgacagc tctaggtgca gctggtgaca atctcctctt
    58321 gaagattggt tcttatattc cctttatttc gaccttcttt atgccgtttc gaacgattaa
    58381 tggctatgcg gagggagcgg aagcatggat ttcacttgct attacagtga tttttgcggt
    58441 ggtagcaaca ggatttatcg gacgcatgta tgctagtctc gttcttcaaa cggatgattt
    58501 agggatttgg aaaaccttta aacgtgcctt atcttataaa tagaagagcc ttgcgaaagc
    58561 gaggttttta aaggtgaaaa gggtggaatc acgaacctaa ttatgtacac attatgtaaa
    58621 caggttgctt gaaaactcaa ttgtatagtg aactgaatct ggaataggat aatattactt
    58681 ctaaaacatt cttataaatt gatttgaatt ccaaaatccc atcgttccgt tcttatttca
    58741 ttttgcgata tagcgaaagg aaataagtca gctcacaaaa aacgcataat atcaaggatt
    58801 tttaacactt gatactatgc gttttctaat tttaaagact ttttgcctgg tctcttttgt
    58861 tctatgagta tgttacatat ctaggtaaaa attatttaaa gcaaattaac cttatttctc
    58921 aagatgtagt aggttccgag ataaaagata gctatgaata tgagttcttt aacaatggct
    58981 atacctgctc ccatatagaa atggtcattg agtcctacca gtgaattgac atagaaattg
    59041 gaactaagat tgaagaaaag ttcaataaat ccaatgacga tttggatacc aatgtaggct
    59101 gcaacagcga gtgctgtacg gtattcattg aaaagctgtc caatggaaat agccaggtag
    59161 atgcagagga ttcctgaaat ggtatttagt aggaaggata tacctgtaag aaagatctga
    59221 gggagatgtg tttctacaaa tgtaatcaca taagaaagag gaatccattc tggagctgtt
    59281 aaagccagaa taataacagc acttagagcc aatacagcgg tgctaatcaa tgaccagata
    59341 aaggcaccga ttagtttggc tgtgatgata tggtgttcag aaactggcaa ggtcaaagtc
    59401 agatagcctt gtcggtcgta gacactacct ttgaagcgtt taataatcaa gaaaatggtt
    59461 gaaatcgcaa gtgtaagcat caagccacca aagactgtag ctagaaaaag tagcatagta
    59521 gcctgacttt cttggtaagg tagattttta aagccttgtg tctgtattcc gatgagggca
    59581 gaaaggacta gcacggctgc gtagagggct aaataccact tgttaacatt tttaaattcg
    59641 tagtgaacta aattccaaaa cataaataat ctcctttgct taggccttaa attcctgacg
    59701 gaagagttgg tcaatggatt cacctgactc gtagcgaata tcatctacat ttccttgacg
    59761 gacgactttt ccgtctttta ggaagacaat ttcatccaag attggctcga tatcagaaat
    59821 caagtgggta gaaatcaaaa cggtagaagt tggtgagtag ttgttgataa tggtattgag
    59881 gatataagca cgggctgctg gatccacccc accaatgggt tcatccaaaa catagagacg
    59941 agcatcacgg ctcataacca aaatcagttg aaccttttct ttgtttcctt ttgatagttt
    60001 cttgagacga ctattttcat caatgcccag gtctgcaagt agatgatgag cgcgttcaag
    60061 attgaaatct ttatagaagg tcttgaagta ggttagggct tctttgacct tcatttgctc
    60121 attgagatag gtcgtatcag gcaaataagc tacaacggcc ttggttgctg ggcttgggtc
    60181 catgtcgttg atgaggacac gtccttgatc tggttgtaag aggccattaa ttagtttaat
    60241 cagggttgtt tttcctgagc cgtttggccc aagaaggccg acaatttttc cagctggaat
    60301 gtcaagagaa acattttcaa gggctggtgt tgctccatat gatttggata cattttcaaa
    60361 tgctagtaat gacataggct taaactcctt taatataatc actgactacg cctggtagtt
    60421 cttctttttc atagccaaaa tgggtcatgg aggaaacgaa gtgttccaat tcttcttctg
    60481 ataattgttt gcgtgactgg gcgattagct ccttatcctt agtcacaaat cgtccagttg
    60541 ttcgcttgct gtagacaaat ccttctcgtt caaggtctga taaggctctt tggatggtat
    60601 tgggattgac accagcctcg ctagctagct ccctcacggt tggaagttgt tgattgggtt
    60661 ccagtgtatg ggaaacaatc tgaagcttga ttttctccat aatctgtaaa tagatgggtt
    60721 ttttgttgtc aaatgtccag gacatcttag tctcctttct tttacccttt tgtcttaatt
    60781 aaataataca acaaaacaaa aaacttgtca agcaaaaaga agaattgttt tgggaatcgc
    60841 ttaaaaaatg gtataatgaa aagaaaacga taaggaggga aaggatgcgt tgtccaaaat
    60901 gtggggctac caagtcaagt gttatcgata gtcgccaagc agaagaaggg aacaccattc
    60961 gtagaagacg tgagtgcgac gaatgccaac accgttttac aacctacgaa cgagtagaag
    61021 aaagaacctt agtggttgtt aaaaaagatg gcacacggga acaattctcc agagataaaa
    61081 tctttaatgg gattatccgc tcagcccaga aacgtcctgt gtcaagtgat gaaatcaaca
    61141 tggtagtcaa tcgtatcgaa cagaaactcc gtggtcgaaa tgaaaatgaa attcaaagtg
    61201 aggacattgg ttcactcgtc atggaggagt tggctgaatt ggacgagatt acctatgtac
    61261 gttttgctag tgtctatcgt agttttaagg atgtcagtga gttagagagc ttgctccaac
    61321 aaatcaccca gtcctctaaa aagaaaaagg aaagataaat gaagccaatt gaccgttttt
    61381 cttatctaaa gaataatcgg gtgtcgcaag atacctcatc tctggtacag tgctacctcc
    61441 cgattatcgg tcaggaggca ctgagccttt atctttatac aatcagtttt tgggataatg
    61501 gtagaaagga atatcttttt tcaagcattc tcaaccatct taactttggg atggatagac
    61561 tgataaaatc attgaaaatc ttatctgctt ttaatctctt gaccctctat caaaaggggg
    61621 atgtttatca gctagtcctc catgctcctc tatctagtca agacttcttg gagcatcctg
    61681 tttatcgcag actcttagag aaaaagattg gcgatgtagc tgtggaggat ttgaaagttg
    61741 aaagtgctga tggtgaagaa atacctgtct cactcaatca agtctttcca gaattggcag
    61801 aactaggcag tcaagaagac cttggtctca agaagaaagt ggccaacgat tttgacttgg
    61861 accattttcg ccagctgatg gctcgagatg gacttcgttt tgcggatgag cagtccgatg
    61921 tcttaaacct ctttgctatt gccgaggaga agaaatggac ttggtttgaa acctatcaat
    61981 tggccaagtc aacagctgtt tctcaggtta tttcaaccaa acgcatgcgg gaaaaaattg
    62041 ctcaaaaacc agtttcctct gactttagtc ttaaggaaac aaccattatc aaagaagcca
    62101 aaagtaaaac tgccctgcag ttcttggcag aaatcaagca aacacgcaag ggaaccatta
    62161 cccaaacaga aagagaactc ttgcaacaga tggctggctt gggcttgctg gacgaagtca
    62221 tcaatatcat tcttttattg acctttaata aggtcgattc ggcaaatatc aatgagaaat
    62281 atgccatgaa ggtagccaat gactatgcct atcaaaagat tcattcggca gaaaaggcag
    62341 tcttgcgcat ccgtgagcga ggacagaaag caaaaataca aaaacagaat cagactgccc
    62401 cagtaaaaac caatgttcct aaatggagta atcctgaata taagaatgaa accagcgagg
    62461 aaactcgtct ggaactagaa cgtaagaagc aagaactatt agctcgatta gaaaaaggag
    62521 gagattagat ggaaagtgtc ggagacgtac tcaaacgtca acccagccgt ttttattatc
    62581 aagatttggt ccagaaaatc atgaaggacc ctgatgttgc ggcttttatc cagcaagaat
    62641 ccttgactcc agaggaatta aatcgcagta tctccaagtt taatcagtac atcaccgagc
    62701 gtgacaagtt tctccgtggg gatacggatt atattgccaa aggctacaag ccgattttgg
    62761 ttaagaatca tggctatgca gatgtttcat atgaagaaac tcctgagcta atcgcggctg
    62821 aaaaagaagc ggctattaag aaccgtctca agttaatcaa tctaccagcc agtctcaaga
    62881 aagctagttt ggctcaagtt gacttggatg atttggggcg cttaccagtt tttgaaaagc
    62941 tactagcctt cgtggagcaa tatccagcta ttcgaaaagg tctttactta tatggagact
    63001 ttggtgtggg taaaagtttc atggtggcgg ccttagctca tgatttatca gaaaaacgtg
    63061 gtgtttcatc aactctcctc cactatccta gctttgtcat tgatgtcaaa aatgctatca
    63121 gtgatggcaa tgttaagacc ttggtggatg agattaagct gtctgaggtc ctgattttag
    63181 atgatattgg cgccgagcaa tcaaccgttt gggtgcgtga cgaaatcctg caggtcattc
    63241 tccaatatcg gatgcaggaa aatttaccga cctttttcac atccaacttc aactttgaag
    63301 atttggagaa gcattttgcg aaagtgaaac atggaaatga cgaaacctgg gaagccagac
    63361 gggtcatgga acgcatccgt tatttggctg aggagactcg tttagaagga gtaaaccgtc
    63421 gatgacagaa accattaaat tgatgaaggc tcatacttca gtgcgcaggt ttaaagagca
    63481 agaaattccc caagtagact taaatgagat tttgacagca gcccagatgg catcatcttg
    63541 gaagaatttc caatcctact ctgtgattgt ggtacgaagt caagagaaga aagatgcctt
    63601 gtatgaattg gtacctcaag aagccattcg ccagtctgct gttttccttc tctttgtcgg
    63661 agatttgaac cgagcagaaa agggagcccg acttcatacc gacaccttcc aaccccaagg
    63721 tgtggaaggt ctcttgatta gttcggtgga tgcggctttg gctggacaaa atgccctgct
    63781 ggcagctgaa agtttgggtt atggtggtgt gattattggc ttggtacggt acaagtcaga
    63841 agaagtggca gaactcttta acctgcctga ctacacctat cctgtctttg ggatggcact
    63901 aggtgttcca aatcaaactc atgatgtgaa accgagactg ccactagata atgtagtctt
    63961 tgaggaagaa taccaagaac agtcaactga ggcaatccaa gcttatgacc gtgtgcaggc
    64021 tgactatgct ggagcgcgtg cgaccacaag ctggagtcag cgtctagcag aacagtttgg
    64081 ccaagcagaa ccaagctcaa ctagaaaaaa tcttgaacag aagaaattat tgtagaaagt
    64141 gagaaattat ggccctacca actattgcca ttgtaggacg tcccaatgtt gggaaatcaa
    64201 ccctatttaa tcggatcgct ggtgagcgaa tctccattgt agaagatgtc gaaggagtga
    64261 cacgtgaccg tatctatgca acgggtgagt ggctcaatcg ctcttttagt atgattgata
    64321 caggaggaat tgatgatgta gatgctcctt tcatggaaca aatcaagcac caggcagaaa
    64381 ttgccatgga agaagcagat gttatcgttt ttgtcgtgtc tggtaaggaa ggaattactg
    64441 atgcagacga atacgtagct cgtaagcttt ataagaccca caaaccagtt atcctcgcag
    64501 tcaacaaggt ggacaaccct gaaatgagaa atgatatcta tgatttctat gctctcggtt
    64561 tgggtgaacc attgcctatc tcatctgtcc atggaatcgg tacaggggat gtgctagatg
    64621 cgatcgtaga aaatcttcca aatgaatatg aggaagaaaa tccagatgtc attaagttta
    64681 gcttgattgg tcgtcctaac gttggaaaat caagcttgat caatgctatc ttgggagaag
    64741 accgtgttat tgctagtcct gttgctggaa caactcgtga tgccattgat acccacttta
    64801 cagatacaga tggtcaagag tttaccatga ttgatacggc tggtatgcgt aagtctggta
    64861 aggtttatga aaatactgag aaatactctg ttatgcgtgc catgcgtgct attgaccgtt
    64921 cagatgtggt cttgatggtc atcaatgcgg aagaaggcat tcgtgagtac gacaagcgta
    64981 tcgcaggatt tgcccatgaa gctggtaaag ggatgattat cgtggtcaac aagtgggata
    65041 cgcttgaaaa agataaccac actatgaaaa actgggaaga agatatccgt gagcagttcc
    65101 aatacctgcc ttacgcaccg attatctttg tatcagcttt aaccaagcaa cgtctccaca
    65161 aacttcctga gatgattaag caaatcagcg aaagtcaaaa tacacgtatt ccatcagctg
    65221 tcttgaacga tgtcatcatg gatgccattg ccatcaaccc aacaccgaca gacaaaggaa
    65281 aacgtctcaa gattttctat gcgacccaag tggcaaccaa accaccaacc tttgtcatct
    65341 ttgtcaatga agaagaactc atgcactttt cttacctgcg tttcttggaa aatcaaatcc
    65401 gcaaggcctt tgtttttgag ggaacaccga ttcatctcat cgcaagaaaa cgcaaataaa
    65461 aaagtagaat ctggaatgac agttccggat ttttttgata taataaaata atagaaaacg
    65521 ctatcaaaag aaggggggat gtcggtgatg gaacatttgt ttaaattctt acttttagca
    65581 ccgtactttt attttgataa ctggattgaa aaggccaaca gaaatagtaa gttttttcca
    65641 attttttatt atttttactg gttttacatc cccttctatt ctctttttag ccttgcttgg
    65701 acagttgttt cagttctgtt tttcaatacc gtcttgagaa atgtgacaga tatcaagtta
    65761 tggggcattt ggtttctttt tattctgcta gctattggta tgaattggtt aacttattcc
    65821 tgtttcaaag aaatgtttcg cttgagacag gaactaggga agtctaaggg tggaaggcat
    65881 tgatttatat cggtttctat ttgtaggagg tggcttatgg tacctctaaa atcatttatt
    65941 acacgctatt ccaaggttta tattggtaat aacatttaat agaacgaaac taaagaaaat
    66001 aatttaaaag aggaggtttg tgatggaaca cttgtttaaa atgataatct tattaccctg
    66061 tttttacttt ttcagctgga ttgacaagga taatagagaa agtaaatttt tcccaatttt
    66121 ttactatttt tactggattt acatcaccct ctatgctctt tttagccttg cttggacagt
    66181 tttttcagtt ctgtttttca atatcgtctt gagaaatttg acagatatca agttatgggg
    66241 tatttggcta ttattactac ttatcgcttt tgctagtgac tggttagact atatctgttt
    66301 caaaaaaatg cttgacttga gacgggaact agggaagtct aaaggcggaa ggcattgatt
    66361 tatactcttc gaaaatctct tcaaaccacg tcaacgtcgc cttggattat atatgtaact
    66421 gacttcgtca gtcttatcta caacctcaaa gcagtgcttt gagcaacttg cggctagttt
    66481 cctagtttgc tctttgattt tcattgagta ttatattact ttctatttgt aggaggtggc
    66541 ttatgaagat tcctctctta actttggcaa ggcataaatt tgtttatgtc ttgcttactt
    66601 tgctttttct tgctttggtt tatcgtgatg ttttgatgac ttatttcttt tttgatattc
    66661 atgcgcccga tctagctaaa ttcgatggac aagcaattaa aaatgactta ttaaaatcag
    66721 cattagattt tcgtattctc cagttcaatc taggttttta tcaatcattt attattccaa
    66781 tcatcattgt tttgctaggt tttcaatata ttgagctgaa aaataaagtt ttacgattga
    66841 gtattggaag agaagtgagt tatcaagggt taaaaagaaa gttgactttg caagttgcaa
    66901 gtatcccttg tttgatatat ttagtgactg tgctgataat tgcaatttta actcatttct
    66961 ttgggacttt ttctcctctt ggatggaatt ctctattttc tgatgggagt agtttacaaa
    67021 ggctcctaga tggagagata acaagctatt tgttctttac ttgtgtccta ctaatcggta
    67081 ttttcatcaa tgcagtctat tttttacaaa tagttgatta tttaggaaat gtgactcgtt
    67141 cggcaatcac ctatttgatg tttctttggc ttggttctat gctgctctat agtgccttgc
    67201 cttactatat ggttcctatg acgagtttga tgcaagctag ctatggggat gtaagtttga
    67261 tgaaactctt tactccttat atcctttata ttgtctctta catggtgctt gaaaaatatg
    67321 aagataatgt ttaagaattt taacaatatt ttgctaaaga gaaagattgt tttactactt
    67381 cgtatagttc tgatgatgat tttgataaac catctattgt caacagcggt tcaaaagcag
    67441 gatgctgtta tctttttcaa gagagaattg atttcaattt tttcctataa tgactattct
    67501 gaagtgaatt tagaaatccc caaactcttg ttaaaccttt cgcttttcat ggtaggatgg
    67561 ctctctgtca ttttacttga aagtgatttg gcagaccatt accatcactt gattcgctat
    67621 caatcaagct cctttttcga ttatacaagg aaacgattgg ttgtcatttc taaatttttt
    67681 actcaagatt tgtttgtctg gtttcttggt ttacttcctc taggaattca tttcaaaaca
    67741 gtcgcacttt tctttttact tgctcagtta atgatgttgt acttactact gtcttatctg
    67801 atagcactga ttagtgcggg cgctggtttt tccttttttc tctatttttt agcatttgtg
    67861 ggacaagaat ggatgatgga tcatattgta acagtgtatt tactactctt aagtttatta
    67921 gttatgttga ttgttagtcg cttggaagag aaatttaaga aaggataaac gatgagactt
    67981 gaaattataa atggacagaa aatttatagg aaaagaccta ttttaaatca gttgaatttg
    68041 gtgtttcaat caggaaaaat ttatggactt aaaggtgata atggatctgg caagacggtt
    68101 cttttaaaga tacttgctgg ttatattaag cttgacaaag gaaaagttct tcaagatggt
    68161 aaagtttacg gggtaaaaaa tcattatatt caggatgcag gaattttaat tgaaaaagtc
    68221 gagtttttat ctcatttatc cctgagagaa aatttggaac tgttaaggta tttttcatct
    68281 aaagttacgg aaaaaagaat tgcctattgg attcaatact atgatttaca ggaatttgaa
    68341 gacattgaat accgtcattt atccttagga acaaagcaaa aaatggcctt gattcaagcc
    68401 tttatttcct ctccttctat actctttctc gatgaaccta tgaatgcttt ggatgagaag
    68461 agtgtgaggt taaccaaaca ggtcatttta tcttacctga aaaaagaaaa tggtctggtt
    68521 atcctgacgt cgcacatatc ggaagatatt tcagaccttt gtacagatgt attagttgtc
    68581 gaaaatggac atatacaaat gtaaaggata tacaatccta ggagatggct tatggcacat
    68641 ctaaaatcat ttattacacg ctattccaag gtttatattg gtttagttct gctgatctgg
    68701 ctgtctttct tctttatccc ttgggataaa ccacttctgg ggataaggat tgacatcttc
    68761 atcatacaga aaatcttgct agcttttgga attctgtcca ttctcatggc cttgctgtcc
    68821 aagaaagtca gtctctttgt ttttggactg atttgctgtc tttctctttg gattaactta
    68881 tttatcacac ttgccatttt gccgattttt ggcaattaaa cagtcataaa agtcggagag
    68941 gttagcttga aaactaacct ctttttcctt ttcaaaatgg ggattcttcc ttgaaaataa
    69001 tcagtaattg tgctaaaatt aaaggaacat tctaaaatat tcggaattta aagtaaggaa
    69061 aaacatggct aatattttaa aaacaattat cgaaaatgat aaaggagaaa tccgtcgtct
    69121 ggaaaagatg gctgacaagg ttttcaaata cgaagaccaa atgactgctt tgactgacga
    69181 ccaactaaaa gcaaaaacag ttgaatttaa ggaacgttat caaaatggag aatcactgga
    69241 ttcattgctt tacgaagcat ttgcggttgt ccgtgaaggt gccaaacgtg tcctaggtct
    69301 cttcccttat aaggttcagg tcatgggggg gattgttctt caccatggtg acgtgccaga
    69361 gatgcgtaca ggggaaggga aaaccttgac tgcgaccatg ccggtatacc tcaatgccct
    69421 ttcaggtaaa ggggttcacg tagttacggt taatgaatac ctgtcagaac gtgacgcgac
    69481 tgagatgggt gaattgtact cttggcttgg tttgtcagta gggattaact tggctaccaa
    69541 atctccaatg gagaaaaaag aagcctatga gtgtgatatt acttactcaa ctaactcaga
    69601 aatcggattt gactaccttc gtgacaacat ggtcgttcgc gctgaaaaca tggtacaacg
    69661 tccgcttaac tatgccttgg tcgatgaggt tgactctatc ttgattgacg aggctcgtac
    69721 acctttgatt gtatcaggtg ccaatgcggt tgaaaccagt cagttgtatc acatggcaga
    69781 ccactatgta aaatctttga acaaagatga ctacatcatc gatgtgcagt ctaagactat
    69841 tggtttgtct gattcaggga ttgacagggc tgaaagctac ttcaagcttg aaaacctcta
    69901 tgacatcgaa aacgtggctt tgacccactt tatcgataac gcccttcgtg ccaactacat
    69961 catgcttctc gatattgact atgtggtgag cgaagagcaa gaaatcttga ttgtcgacca
    70021 atttacaggt cgtaccatgg aaggtcgtcg ttattctgat ggattgcacc aagctattga
    70081 agccaaagaa ggtgtgccaa tccaggatga aaccaagaca tctgcctcaa tcacgtacca
    70141 aaaccttttc cgtatgtaca agaaattgtc tggtatgacg ggtacaggta agactgagga
    70201 agaagaattc cgtgaaatct acaacattcg tgttattcca atcccaacaa accgtcctgt
    70261 tcaacgtatt gaccactcag accttcttta tgcaagtata gaatctaagt ttaaagcggt
    70321 tgtcgaagac gttaaggctc gttaccaaaa gggtcaacct gtcttggttg gtacagtagc
    70381 ggttgaaact agtgactaca tttctaagaa attggttgca gctggtgttc ctcacgaagt
    70441 cttgaatgcc aaaaaccact atagagaagc ccaaatcatc atgaatgctg gtcaacgtgg
    70501 tgccgttacc atcgcaacca acatggcggg tcgtggtacc gacatcaagc ttggtgaagg
    70561 tgttcgtgaa cttggaggac tttgtgttat tggtacagaa cgtcatgaaa gtcgtcgtat
    70621 cgataaccag cttcgtggac gttcaggtcg tcaaggagat ccaggtgagt cacaattcta
    70681 cctatctctt gaagatgatt tgatgaaacg ttttggttct gaacgcttga agggaatctt
    70741 tgaacgcttg aacatgtctg aagaggcgat tgagtctcgc atgttgacgc gtcaggttga
    70801 agcagctcag aaacgtgtcg aaggaaataa ctacgatacc cgtaaacaag tccttcaata
    70861 cgatgatgtc atgcgtgaac aacgtgagat tatctatgct caacgttacg atgtcatcac
    70921 tgcagatcgt gacttggcac ctgaaattca gtctatgatc aaacgcacga ttgaacgtgt
    70981 cgttgatggt catgcgcgtg ccaaacaaga tgaaaaacta gaggcaattt tgaactttgc
    71041 taagtacaac ttgcttcctg aagattctat tacgatggaa gacttgtcag gcttgtctga
    71101 taaggccatc aaggaagagc ttttccaacg tgccttgaag gtttacgata gtcaggtttc
    71161 aaaactacgc gatgaagaag cagttaaaga attccaaaaa gttttgattc tacgagtagt
    71221 ggataacaag tggacagatc atatcgatgc ccttgatcaa ttgcgtaacg cggttggact
    71281 tcgtggctat gctcagaaca accctgttgt tgagtatcag gcagaaggtt tccgtatgtt
    71341 taatgatatg attggttcga ttgagtttga tgtgacacgc ttgatgatga aagcacaaat
    71401 tcatgaacaa gaaagaccac aggcagaacg tcatatcagt acaacagcga ctcgcaatat
    71461 cgctgctcac caagcaagta tgccagaaga tttggatttg agccagattg gacgcaatga
    71521 actttgccca tgtggttctg gtaagaaatt taaaaactgt cacggtaaaa gacaataaaa
    71581 tgagatagtt tagaggcgga tatcttgtga aaagtaaatt tttactgggt atccgtttgc
    71641 tttataagga gatgagttat ggtatttaca gcaaaaagct ctaaaataaa tatagaagaa
    71701 gttcgtgcct tgtcaaaatt agaaggtcag gctttggaga ggaaatcaca gcgagatcaa
    71761 gagctagaag ccattatacg tggagaagac cagcgaattc tcttggtaat cgggccatgc
    71821 tcatctgaca acgaagaagc tgtccttgaa tacgctaagc gtttggcagt cctacaagaa
    71881 gaagtggcag atcgtatctt tatggttatg cgtgtttata ctgccaaacc ccgtaccaac
    71941 ggagatggct ataagggctt gattcaccag cctaacgcga cagaagcgcc tagtcttatc
    72001 aatggaatca aagccgttcg ccatcttcac tatcgtgtca tcacagaaac agggatgaca
    72061 actgctgatg aaatgcttta tcctgaaaac cttccgcttg tagatgattt gatttcttac
    72121 atggcagttg gtgcccgttc agttgaagac cagcaacacc gctttgtggc aagtggggca
    72181 ggattttcta ctggttttaa aaatccaacc tctggaaatc tcaatgtcat gtttaatggg
    72241 atttatgctg ctcaaaacaa acaaagtttc cttttcttag gaaaagaagt agaaacaact
    72301 gggaacccgc tttcacacgc tattcttcgt ggtgctctta atgagtatgg aaaaaatatt
    72361 cccaactact attatgacaa tttaattgat accattgccc agtatgagaa aatgggcttg
    72421 gaaaatcctt ttatcatcat tgataccaat catgacaatt ctggtaagca gtatattgaa
    72481 cagatccgaa ttgtccgcca gaccttgatt aaccgtgctt ggaatgaaaa aattaagcag
    72541 ttcgttcgtg gttttatgat tgagtcttat ctggaagatg gtcgacaaaa tgagccagaa
    72601 gtatttggta agtctatcac agacccttgc ctgggttggg ataacacaga agctcttgtc
    72661 agagaaattt acaaaacgtt aggagaataa gatggcattt attgaaaaag gtcaagaaat
    72721 cgatatggaa gtcatcaagg ctgaaaccca attgtctgcg gaagccttga gactcaagga
    72781 aagccgtgac agggaattgg cagatattat ttcaggggaa gatgaccgta ttctcttggt
    72841 gattggtcct tgctcttctg ataatgaaga ggcggtcttg gaatatgctc gccgtttatc
    72901 cgccttgcaa aagaaggtag cggacaagat tttcatggtc atgcgcgtgt atactgctaa
    72961 gcctcgtacc aatggagacg gctataaagg attagttcac cagccagata cttctaaggc
    73021 tccaagcctg attaatggct tgcaggctgt gcgccagttg cactaccgcg tgattacaga
    73081 gactggtttg acaacggcag atgagatgct ttatccgtca aatctgatct tggtggatga
    73141 cttggtcagc taccatgccg ttggagctcg ttctgtggaa gaccaagagc accgctttgt
    73201 ggcttctggg attgatgcac cagtagggat gaaaaatcca acctcaggaa atttgggtgt
    73261 tatgtttaac gccatctatg ctgctcaaaa caagcaaacc ttcctttatc atgggcagga
    73321 agttgagaca tcaggtaatc ctttggccca tgttatcctc cgtggagcag tcaacgagta
    73381 tggcaattat atgccgaatt actactatga aaacctactc caagccattg aacgctatga
    73441 aaccatggga cttgaaaatc cttttatcct cattgacacc aaccatgata actcaggcaa
    73501 gcaatatatg gagcagattc gaattgttcg ccagaccttg cagaatcgtg attggaatga
    73561 gaaaattaaa aagacggttc gaggatttat gattgaatct tacctagcag atggtcgtca
    73621 aaaccaacca gagatctttg gttgctctat tactgaccct tgcctaggtt gggaaaatac
    73681 agaggccttg gtagaagaga tttatgttac cttgacaaaa taagtgaaaa ggatggagtt
    73741 ggggaatctc aactcctttt gatgagaatg atagttggac acggaattga catcgaagaa
    73801 ttggcttcga tagaaagtgc agttacacga catgaaggat ttgctaagcg tgtactgacc
    73861 gctcaggaaa tggagcgctt caccagtctc aaaggacgca ggcaaataga atatttagct
    73921 ggtcgctggt cggctaagga ggccttttcc aaggctatgg gaacgggcat tagcaagctc
    73981 ggttttcagg atttggaagt cttgaacaat gaacgtgggg cgccttattt tagtcaggca
    74041 ccattttcag gaaagatttg gctgtctatc agccacaccg atcagtttgt gacagccagt
    74101 gtcattttgg aggaaaatca tgaaagctag tccacataga ccaaccaagg ctctgattca
    74161 tctgggagct attcgacaaa atattcagca aatgggggct catatccctc aaggaacgct
    74221 caagttggct gtggttaagg ccaatgctta tggtcatgga gctgttgccg ttgccaaggc
    74281 aattcaagat gatgttgatg gcttttgcgt ttccaatatc gatgaagcca ttgaactcag
    74341 acaagctgga ctcagcaagc caattctcat tttaggagtt tctgaaatcg aagctgttgc
    74401 tctagctaaa gaatatgact tcaccttgac agtggctgga ctggagtgga ttcaagcact
    74461 cttagataag gaagtggacc taactggatt gacagtccac ctcaagattg attcagggat
    74521 gggacggatt ggttttagag aggccagtga ggttgagcag gctcaagatt tgctccaaca
    74581 acacggtgtt cgtgttgaag gaatctttac ccactttgct actgctgatg aggaatcaga
    74641 tgactatttt aatgcccagt tagaacggtt taaaactatt ttagctagta tgaaggaagt
    74701 tccagagctg gttcatgcta gcaattctgc aacgactctt tggcatgtag agactatttt
    74761 caatgcggtt cgtatgggag atgccatgta tggcctcaat ccaagtggag cggtcttgga
    74821 tttgccttat gatttgatac cggccttgac cttggagtct gctctggttc atgtcaagac
    74881 agttccatct ggagcttgca tgggatatgg agcaacttat caagcggata gcgagcaagt
    74941 catcgcgacc gtgccaatcg ggtatgcaga tggatggaca agagacatgc aaaatttctc
    75001 tgtcttggta gatggccaag cttgcccaat tgtcggcagg gtttcgatgg accaaatcac
    75061 tattcgattg cctaagcctt acccactcgg aaccaaggta accttgattg gctccaatgg
    75121 ggataaggaa atcactgcaa ctcaggtagc gacctaccgc gtaaccatta actatgaggt
    75181 ggtttgcctc ctcagcgacc gtattccgag agaatattat tagaaaagaa aggagtggag
    75241 catgaatcta catcaaccct tgcatgtctt gcctggtgtg ggaccaaagt cagcagaaaa
    75301 atacgccaaa ctaggaattg aaaacttgca agatctcttg ctctactttc ctttccgtta
    75361 tgaagacttc aaaaccaagc aggtgctgga gctggaagac ggtgagaagg cagttctttc
    75421 tggtcaggta gtgactcctg ctagtgtcca gtattatggt ttcaagcgca atcgcctgcg
    75481 ttttagtctc aagcagggag aggtcgtttt tgcggtgaat ttctttaacc agccctatct
    75541 ggctgataaa atagagttgg gagcaaccct tgctgtcttt ggaaaatggg accgcgctaa
    75601 ggctagtctg actgggatga aggttctggc tcaggtagaa gatgacctcc agcctgttta
    75661 tcgtctggct cagggaatca gtcaggccag tctggttaag gtcatcaaga cggcttttga
    75721 tcagggactg gacctcttga tagaagaaaa tctgccccag tctttactag acaaatacaa
    75781 actcatgtcc cgttgtcagg cagtccgagc tatgcatttt ccaaaggatt tggcagaata
    75841 caagcaggct cttcgccgta taaagtttga ggaactcttt tatttccaaa tgcagctgca
    75901 gacgctcaag tctgaaaata gaattcaggg aagtggtctg gttctggatt ggtctcagga
    75961 aaaagtgaca gcagttaaag caagtcttcc ttttgccctg acccaagctc aggaaaagag
    76021 tttgcaggaa attttaactg atatgaagtc cgaccaccac atgaatcgtc tcctacaagg
    76081 ggatgtgggg agtggaaaaa cggtagtcgc tggcttggcc atgtttgcgg cagtgacagc
    76141 aggttatcag gctgccctaa tggtaccaac agaaatcctc gcagagcaac actttgagag
    76201 tttacagaac ctttttccca atttgaaact ggctctcttg acaggttcct tgaaagctgc
    76261 agaaaagaga gaagtcttgg agaccattgc caagggtgag gctgatttga ttataggaac
    76321 tcacgctctg atacaagatg gggtggagta tgctcgtctt ggtttgatta ttatcgatga
    76381 gcagcaccgt tttggtgtag ggcaaaggcg tattttacgg gaaaaaggtg acaatccaga
    76441 tgtcctcatg atgacggcga ctcccattcc acggacgctt gccatcacag cctttggaga
    76501 tatggatgtt tccattatcg accagatgcc agcaggtcgg aagcctattg tgacgcgctg
    76561 gatcaaacat gagcaactac ctcaggtctt gacttggtta gagggggaaa ttcaaaaagg
    76621 ttcccaagcc tatgtcatct ctcctttgat tgaagaatca gaagctctag atttgaaaaa
    76681 tgccattgcc ttatcagaag agctgacggc tcattttgca ggcaaggcag aggtggctct
    76741 tctacatggt aggatgaaga gtgacgaaaa agaccagatc atgcaggatt tcaaggagag
    76801 aaagacggat attctggttt cgacgacggt tattgaggtt ggggtcaacg ttcccaatgc
    76861 gactgtcatg attatcatgg atgccgatcg cttcgggctc agccagcttc accagcttag
    76921 aggtcgtgtc ggtcgggggg acaagcagtc ctacgctgtt ctcgttgcca atcccaagac
    76981 ggattctggg aaagaccgca tgcgcatcat gacagaaacg accaatggat ttgtccttgc
    77041 ggaggaagat ttgaaaatgc gtggttctgg tgagattttt ggaaccagac agtcaggact
    77101 tccagagttc caagtggctg atattatcga agattttccg attttagaag aagcaagaaa
    77161 ggttgctagc tacattagtt ctatagaagc ttggcaagaa gatccagagt ggcgcatgat
    77221 tgcccttcat ctggaaaaga aagaacatct ggattaagct ttctctaagg aaaacttaag
    77281 ctagttttta ggtttggctc ttatactaaa gtcatcaaaa agaaacgagg actctcatat
    77341 gacagtaacg attaaagtaa attaccaaac cactttccaa aagaaggaag caaaaaacta
    77401 gtataaacag aagagagagc gaaatgctct ttttcgtttc taaaactact ttcagcccat
    77461 catcctaaaa gtaaagaatc taaattcact ttctatttat ccttctttct tgcattgatt
    77521 acatagatat gctacagttg tggtaacgat tacaaaataa aaggagcatg ctatgaaaaa
    77581 tccagctttg ctagaagaaa ttaagaccta tagaggaagg gatgaggttc cggaagactt
    77641 tgatgctttc tgggatgggg aagtgaaaaa tgtttccacg cttccatcct accacttgga
    77701 ggaaagagat ttccacattc ctcaagtcaa gtgctatgag ttaacatttg aaggaagcaa
    77761 ggaaggaaag gtctatgcac gcattgttct tccaaagagt gaggagaagg ttccactaat
    77821 cttccatttt catggttata tgggacgtgg ctgggactgg gccgacatgc tgggcttcac
    77881 cgtagctggt tacggtgttg tttccatgga tgtgcggggc cagtcaggtt actcacaaga
    77941 cggcttgcgt tctcctttag gaaataccgt gaaggggcat attatccgtg gtgctatgga
    78001 aggtcgggac cacctctttt ataaggatgt ttatctggat atttaccagt tggtcgaaat
    78061 tgttgctagt ctgtctcagg ttgatgagaa gcgtctttct agctatggtg cctcacaagg
    78121 aggggctcta gctctagttg cagcagcgct caatcctcga attcagaaaa cagttgccat
    78181 ttatcccttc ttgtcagact tcagacgggt gattgagatt ggtaatacta gcgaggctta
    78241 cgacgaactt ttccgctatt tcaagtttca cgaccccttc catgaaacag aggaggaaat
    78301 catggcgacc cttgcctata tcgatgtcaa aaatcttgcc catcgtatcc aaggtgaggt
    78361 taagatgatt acgggcttgg acgacgatgt ttgctatccc attacccagt ttgcgattta
    78421 taatcgtctg acctgcgata aaacctatcg catcatgcct gagtatgctc acgaagccat
    78481 gaatgtattt gtcaatgacc aagtctacaa ctggctctgt ggaagtgaga ttccttttaa
    78541 atatctaaaa taaggagtcg actctaagca caaaatctta aaaattacaa acacgcatag
    78601 tatcagggga ttaaaaaaac ttgatactat gcgttttatc atggaaatat agtaaaatga
    78661 aacaagaata ggacaaaacg atcaggacag tcaaatcgat ttctaacaat gttttagaag
    78721 caaatgtgta ctattctagt ttcaatctat tatatttata gaattttttg ttgctagatt
    78781 tgtcaaattg cttaaaataa tttttttcag aaagcaaaag ccgataccta tcgagtaggg
    78841 tagttcttgc tatcgtcagg cttgtctgta ggtgttaata cttttcaaaa atctctttaa
    78901 accacgtcag cttcgccttg ccgtatatat gttactgact tcgtcagttc tatctgccac
    78961 ctcaaaacgg tgttttgagc tgacttcgtc agttctatct gccacctcaa aacggtgttt
    79021 tgagctgact ttgtcagtct tatctacaac ctcaaaacag tgttttgagc atcatgcggc
    79081 tagcttctta gtttgctctt tgattttcat tgagtataaa aacagatgag tttctgtttt
    79141 ctttttatgg actataaatg ttcagctgaa actactttca aggacattat tatataaaag
    79201 aattttttga aactaaaatc tactatatta cactatattg aaagcgtttt aaaaatgagg
    79261 tataataaat ttactaacgc ttataaaaag tgatagaatc tatttttatg tatatgtaaa
    79321 gatagattgc tgtaaaaata gtagtagcta tgcgaaataa cagatagaga gaagggattg
    79381 aagcttagaa aaggggaata atatgatatt taaggcattc aagacaaaaa agcagagaaa
    79441 aagacaagtt gaactacttt tgacagtttt tttcgacagt tttctgattg atttatttct
    79501 tcacttattt gggattgtcc cctttaagct ggataagatt ctgattgtga gcttgattat
    79561 atttcccatt atttctacaa gtatttatgc ttatgaaaag ctatttgaaa aagtgttcga
    79621 taaggattga gcaggaagta tggtgtaaat agcataggct gatgtccatc atttgcttat
    79681 aaagagatat tttagtttaa ttgcagcggt gtcctggtag ataaactaga ttggcaggag
    79741 tctgattgga gaaaggagag gggaaaattg gcaccaattt gagatagttt gtttagttca
    79801 tttttgtcat ttaaatgaac tgtagtaaaa gaaagttaat aaaagacaaa ctaagtgcat
    79861 tttctggagt aaatgtctta tttcagaaat cgggatatag atatagagag gatcagtatg
    79921 aatcggagtg ttcaagaacg taagtgtcgt tatagcatta ggaaactatc ggtaggagcg
    79981 gtttctatga ttgtaggagc agtggtattt ggaacgtctc ctgttttagc tcaagaaggg
    80041 gcaagtgagc aacctctggc aaatgaaact caactttcgg gggagagctc aaccctaact
    80101 gatacagaaa agagccagcc ttcttcagag actgaacttt ctggcaataa tcaagaacaa
    80161 gaaaggaaag ataagcaaga agaaaaaatt ccaagagatt actatgcacg agatttggaa
    80221 aatgtcgaaa cagtgataga aaaagaagat gttgaaacca atgcttcaaa tggtcagaga
    80281 gttgatttat caagtgaact agataaacta aagaaacttg aaaacgcaac agttcacatg
    80341 gagtttaagc cagatgccaa ggctccagca ttctataatc tcttttctgt gtcaagtgct
    80401 actaaaaaag atgagtactt cactatggca gtttacaata atactgctac tctagagggg
    80461 cgtggttcgg atgggaaaca gttttacaat aattacaacg atgcaccctt aaaagttaaa
    80521 ccaggtcagt ggaattctgt gactttcaca gttgaaaaac cgacagcaga attgccaaat
    80581 ggtcgagttc gcctgtatgt taatggtgtt ttatctcgaa caagtctgaa atctggcaat
    80641 ttcattaaag atatgccaga tgtaacgcat gtgcaaatcg gagcaaccaa gcgtgccaac
    80701 aatacggttt gggggtcaaa tctacagatt cggaatctca ctgtgtataa tcgtgcttta
    80761 acaccagaag aggtacaaaa acgtagtcaa ctttttaaac gctcagattt agaaaaaaaa
    80821 ctacctgaag gagcggcttt aacagagaaa acggacatat tcgaaagcgg gcgtaacggt
    80881 aaaccaaata aagatggaat caagagttat cgtattccag cacttctcaa gacagataaa
    80941 ggaactttga tcgcaggtgc agatgaacgc cgtctccatt cgagtgactg gggtgatatc
    81001 ggtatggtca tcagacgtag tgaagataat ggtaaaactt ggggtgaccg agtaaccatt
    81061 accaacttac gtgacaatcc aaaagcttct gacccatcga tcggttcacc agtgaatatc
    81121 gatatggtgt tggttcaaga tcctgaaacc aaacgaatct tttctatcta tgacatgttc
    81181 ccagaaggga agggaatctt tggaatgtct tcacaaaaag aagaagccta caaaaaaatc
    81241 gatggaaaaa cctatcaaat cctctatcgt gaaggagaaa agggagctta taccattcga
    81301 gaaaatggta ctgtctatac accagatggt aaggcgacag actatcgcgt tgttgtagat
    81361 cctgttaaac cagcctatag cgacaagggt gatctataca agggtaacca attactaggc
    81421 aatatctact tcacaacaaa caaaacttct ccatttagaa ttgccaagga tagctatcta
    81481 tggatgtcct acagtgatga cgacgggaag acatggtcag ctcctcaaga tattactccg
    81541 atggtcaaag ccgattggat gaaattcttg ggtgtaggtc ctggaacagg aattgtactt
    81601 cggaatgggc ctcacaaggg acggattttg ataccggttt atacgactaa taatgtatct
    81661 cacttaaatg gctcgcaatc ttctcgtgtc atctattcag atgatcatgg aaaaacttgg
    81721 catgctggag aagcggtcaa cgataaccgt caggtagacg gtcaaaagat ccactcttct
    81781 acgatgaaca ataaacgtgc gcaaaataca gaatcaacgg tggtacaact aaacaatgga
    81841 gatgttaaac tctttatgcg tggtttgact ggagatcttc aggttgctac aagtaaagac
    81901 ggaggagtga cttgggagaa ggatatcaaa cgttatccac aggttaaaga tgtctatgtt
    81961 caaatgtctg ctatccatac gatgcataat ggaaaagaat acattatcct cagcaatgca
    82021 ggtggaccga atcgtgaaaa tgggatggtc cacttggcac gtgtcgaaga aaatggtgag
    82081 ttgacttggc tcaaacacaa tccaattcaa aaaggagagt ttgcctataa ttcgctccaa
    82141 gaattaggaa atggggagta tggcatcttg tatgaacata ctgaaaaagg acaaaatgcc
    82201 tataccctat catttagaaa atttaattgg gaatttttga gcaaagatct gatttctcct
    82261 accgaagcga aagtgaagcg aactagagag atgggcaaag gagagatggg caaaggagtt
    82321 attggcttgg agtttgactc agaagtattg gtcaacaagg ctccaaccct tcaattggca
    82381 aatggtaaaa cagcgacttt cctaacccag tatgatagca aaaccttgtt gtttgcagta
    82441 gataaggaag atatcggaca ggaaattatt ggtatagcta aaggaagcat cgaaagtatg
    82501 cataatcttc ctgtaaatct agcaggtgcc agagttcctg gcggagtaaa tggtagcaaa
    82561 gcagcggtgc atgaagttcc agaatttaca gggggagtta atggtacaga gccagctgtt
    82621 catgaaatcg cagagtataa gggatctgat tcgcttgtaa ctcttactac aaaagaagat
    82681 tatacttaca aagctcctct tgctcagcag gcacttcctg aaacaggaaa caaggagagt
    82741 gacctcctag cttcactagg actaacagct ttcttccttg gtctgtttac gctagggaaa
    82801 aagagagaac aataagagaa gaattctaaa catttgattt tgtaaaaata gaaggagata
    82861 gcaggttttc aagcctgcta tctttttttg atgacattca agctgatacg aaatcataag
    82921 aggtctgaaa ctactttcag agtagtctgt tctataaaat atagtagatt gaaataagat
    82981 gtgaacaact ctatcaggaa agtcaaatta atttatagaa aaattttagc agtcaaggtg
    83041 tactgttata gattcaatat attatacgac tattaacctt atcttctcct aaaattgact
    83101 ttcttgtttt cttatcttgt ccactcgaaa caagtattgt aagaatttga ttatttttga
    83161 aagtactttt aatatacttg atatagttaa aaaagatttg aaactaaatt ccaaattaga
    83221 aaaagacttg aaatactaaa aaaaaagtat actctaattg aaaacggtaa caaaactaat
    83281 ttagagaatg aaatatagag tatttctctc ttaaaagttt ttggtgaaac gagatgtaga
    83341 aaggagattt agccaaagag tctattagtg ctagaataat agattagaat tattttagaa
    83401 aaacgaagtg agcagcttat aaattcaagt ccccaaatag actcatacta gtatcttttg
    83461 caaaaaataa agggcgactt ccttcatgaa tatcaatttc atctataagg aaggtagcta
    83521 attgaactaa cttatttatt ctgtttgtcg ctagaaaaat cagacctcct tgtgaagatt
    83581 gaggagatac ttaatgaaaa tcaaagaaga aactagcaag ctagtagcag attgcccaaa
    83641 acaccgcttt gaggttgtag ataagactga cctatataat ccaaggtgaa gcgactgtgg
    83701 tttgaagaga ttttcaaaga gtatagacta gagagtagtg tttttatgtc cttctagtag
    83761 aaaatgctag acagaagaat ggggaacttg gataggaaaa atagattgag aaaggaggtt
    83821 agaagagatg attattacaa aaattagccg tttaggaact tatgtgggag tcaatccaca
    83881 ttttgcaaca ttaatagatt ttctagaaaa aacaggacta gaaaatttaa cagaaggttc
    83941 gattgctatc gatggtaatc gattgtttgg gaattgcttt acttatctag cagatggtca
    84001 agcaggggat ttctttgaaa cacaccaaaa atatttggat attcatttag ttttggaaaa
    84061 cgaagaagcc atggctgtta catcgccgga aaatgtaagc gttacccaag aatatgatga
    84121 agagaaagat attgaattat acacagggaa agtggaacag ttggttcatt tgagagctgg
    84181 tgaatgcctc atcacttttc cagaagattt acatcaaccc aaggttcgta taaatgatga
    84241 acctgtgaaa aaagttgtct ttaaagttgc gatttcttaa tgtagaaaga gaagaacgat
    84301 gaaaaaaatg agaaagtttt tatgtctagc tggaattgcg ctagcggctg ttgccttggt
    84361 agcttgttca ggaaaaaaag aagctacaac tagtactgaa ccaccaacag aattatctgg
    84421 tgagattaca atgtggcact cctttactca aggaccccgt ttagaaagta ttcaaaaatc
    84481 agcagatgct ttcatgcaaa agcatccaaa aacgaaaatc aagattgaaa cattttcttg
    84541 gaatgacttc tatactaaat ggactacagg tttagcaaat ggaaatgtgc cagatatcag
    84601 tacagctctt cctaaccaag taatggaaat ggtcaactca gacgctttgg ttccgctaaa
    84661 tgattctatc aagcgtattg gacaagataa atttaacgaa actgccttaa atgaagcaaa
    84721 aatcggagat gattactact ctgttcctct ttattcacat gcacaagtca tgtgggttag
    84781 aacagatttg ttaaaagaac ataatattga ggttcctaaa acttgggatc aactctatga
    84841 agcttctaaa aaattgaaag aagctggagt ttatggcttg tctgttccgt ttggaacaaa
    84901 tgacttaatg gcaacacgtt tcttgaactt ctacgtacgt agtggtggag gaagcctctt
    84961 aacaaaagat cttaaagcag acttgacaag ccaacttgct caagatggta ttaaatactg
    85021 ggttaaattg tataaagaaa tctcacctca agattctttg aactttaatg tccttcaaca
    85081 agctaccttg ttctatcaag gaaaaacagc atttgacttt aactctggct tccatatcgg
    85141 aggaattaat gccaacagtc ctcaattgat tgattcgatt gatgcttatc ctattccaaa
    85201 aatcaaagag tctgataaag atcaaggaat tgaaacctca aacattccaa tggttgtttg
    85261 gaaaaattca aaacatccag aagttgctaa agcattctta gaagcacttt ataatgaaga
    85321 agactacgtt aaattccttg attcaactcc agtaggtatg ttgccaacta ttaaggggat
    85381 tagcgattct gcagcctata aagaaaatga aactcgtaag aaatttaaac atgctgaaga
    85441 agtaattact gaagctgtta aaaaaggtac tgctattggt tatgaaaatg gaccaagtgt
    85501 acaagctggt atgttaacta accaacacat tattgaacaa atgttccaag atatcattac
    85561 aaatggaaca gatcctatga aagcagcaaa agaagcagaa aaacaattaa atgatttatt
    85621 tgaggctgtt cagtagatgt aaaagactag aaaataggtg ggctagtgag ctgaaaagct
    85681 ctagcccaat cttgtaaaag aagggagaag gagaatggtt aaagaacgta atttaactcg
    85741 ctggatattt gttttgccag ctatgattat cgtaggatta ctctttgttt atccgttttt
    85801 ctcgagtatt ttttatagct ttaccaataa gcatttgatt atgcctaatt ataaatttgt
    85861 tggtttggct aactataaag ctgtgctatc agatcccaac ttctttaatg cgttctttaa
    85921 ttcaattaag tggaccgttt tctcattagt tggtcaagtt ttagtagggt ttgtattggc
    85981 tttagctctt cacagagtac gccacttcaa gaaattatat aggaccttat tgattgttcc
    86041 ttgggcattt cctaccatcg ttattgcctt ttcttggcag tggattctaa acggggttta
    86101 tggctactta cctaatctaa tcgtaaaatt aggtttaatg gaacatacac ctgcattttt
    86161 gacagatagt acatgggcat tcctatgttt ggtgtttatc aacatttggt ttggagcacc
    86221 aatgattatg gttaatgtgc tttcagcttt gcaaacagta ccagaagaac aatttgaggc
    86281 tgctaagata gatggtgctt caagttggca ggtgttcaag tttatcgtct ttccacatat
    86341 taaagtggtt gtaggacttc tagttgtttt gagaactgta tggatcttta ataactttga
    86401 cattatctac ctcattactg gtggtggacc agccaatgct acaacgacgc ttccaatttt
    86461 tgcttacaac ctgggctggg gaactaaatt gttgggtcgt gcttcagcag ttacagtatt
    86521 gctctttatc ttcttggtgg cgatttgctt tatctacttt gctatcatca gtaagtggga
    86581 aaaggagggt agaaaataat gaagaagaaa tccagtattt atttagatat tctctcacat
    86641 gtacttttag ttggtgcgac catcgttgca gttttcccat tggtatggat tatcatatct
    86701 tctgtcaaag ggaaagggga attaactcag tatccaacac gattttggcc tgaacagttt
    86761 acattagatt atttcactca tgttatcaac gatttgcact tcattgataa cattcgaaac
    86821 agtttaatca ttgccttggc tacaaccctt attgcgatta ttatttctgc tatggcagcc
    86881 tatggtattg ttcgattctt tcctaaattg ggagcaatca tgtcgagact actcgtcatt
    86941 acctacattt tcccaccaat tttgttagca attccctatt caattgccat tgctaaagtt
    87001 gggttaacaa atagtttatt tggcttgatg atggtttatc tatcttttag tgttccatat
    87061 gcagtttggc tcttagttgg atttttccaa acagttccaa ttggaattga agaagcggct
    87121 agaattgatg gtgcaaataa atttgttacg ttttataaag ttgtgctacc gattgtagca
    87181 ccaggtattg tagcaacagc tatttataca tttatcaatg cttggaatga attcctgtat
    87241 gccttgattt tgattaacaa tacaggaaag atgacagtag cagtagccct tcgttcactt
    87301 aatggttcag aaatactaga ctggggagat atgatggcag cgtctgttat tgtagttctt
    87361 ccatcaatta ttttcttctc tatcatccaa aataagattg caagtggatt atcagaagga
    87421 tctgtgaagt aatactcaat gaaaatcaaa gagcaaacta ggaaactagc cgcaggctgc
    87481 tcaaagtaca gctttgaggt tgcagataaa actgacgaag tcagtaacca tacgcacagt
    87541 aaggcgacgt tgacgcggtt tgaagagatt ttcgaagagt ataagttaaa attagaaagt
    87601 ttattcaata ataaaggaga aaaaacatgg ttaaatacgg tgttgttgga gcagggtatt
    87661 ttggagctga attggctcgc tacatgcaaa aaaatgatgg agcagagatt actcttctct
    87721 atgatccaga taatgcagag gcgattgcag aagaattggg agcaaaagta gcaagttcct
    87781 tagatgagtt ggtttctagc gatgaagtag attgtgttat cgtcgcaact ccaaataatc
    87841 ttcataagga accggttatt aaggctgcac agcatggtaa aaatgttttc tgtgaaaaac
    87901 caattgcgct ttcttatcaa gattgtcgcg agatggtaga tgcgtgtaaa gaaaacaatg
    87961 taacctttat ggcaggacat attatgaatt tctttaatgg tgttcatcat gcaaaagaac
    88021 tcatcaatca aggagttatc ggagacgttc tatattgtca tacagctcgt aatggttggg
    88081 aagaacaaca accgtcagtg tcatggaaaa aaattcgtga aaaatcaggt ggtcacttgt
    88141 atcaccacat ccatgaattg gattgcgttc aattccttat ggggggcatg cctgaaactg
    88201 taaccatgac aggtggaaat gtggcccatg aaggtgaaca tttcggtgat gaagatgata
    88261 tgatttttgt caatatggaa ttttctaata agcgttttgc cttgttagaa tggggttcag
    88321 cttatcgttg gggtgaacat tatgtcttaa tccaaggaag caaaggtgcc atccgcttag
    88381 acttattcaa ctgtaaagga actcttaagc tagatgggca agaaagctat ttcttgattc
    88441 acgaatcgca agaagaagat gatgatcgga ctcgtatcta tcatagtaca gagatggatg
    88501 gagcaattgc ttatggtaaa ccaggtaaac gtactccatt atggctatca tctgtcattg
    88561 ataaagaaat gcgctatctg catgagatta tggaaggagc cccagtatca gaagaatttg
    88621 caaaactttt gacaggtgaa gctgccctag aagcaattgc tactgcagat gcttgtaccc
    88681 agtctatgtt tgaagatcgc aaagtaaaat tgtcagaaat tgtaaaataa attttggtat
    88741 tctcctattt ataggtcgac ttgctcctct gaaagtactt ttagaggagc tgtttgactt
    88801 tgctagtttt tgaaactgaa atctattata ctacaaacta ttgaaagcgt tttaatttta
    88861 aggtataata atctcataga aataaagaaa aggaggaaag aggatgccac agattagcaa
    88921 agaagccttg attgagcaaa tcaaagatgg aatcatcgtt tcttgtcagg ctcttcctca
    88981 tgaaccgctt tatacagaag cgggaggggt gattcccttg ctggtcaaag cggctgagca
    89041 aggtggagca gtcggtatcc gagcaaacag tgttcgcgat atcaaggaaa ttaaggaagt
    89101 cactaaactt ccaatcattg ggattatcaa acgtgattat ccacctcagg aacccttcat
    89161 cacggctact atgaaagaag ttgatgaatt ggcagaactg gacatcgagg tgattgctct
    89221 ggattgtacc aagcgtgaac gctacgatgg tttggaaatt caagagttca ttcgtcaggt
    89281 taaggagaaa tatcctaatc agcttttgat ggctgatact agtatcttcg aagaagggct
    89341 agcagctgta gaagcaggaa ttgactttgt cggaacaacc ttatcaggct acacatccta
    89401 cagtccaaaa gtagacggtc cagattttga attgattaag aaactctgtg atgccggtgt
    89461 agatgtcatt gcagaaggaa aaattcatac accagaacaa gccaaacaaa tccttgaata
    89521 tggagtgcga ggcatcgttg ttggtggcgc cattactaga ccaaaagaga ttacagaacg
    89581 cttcgttgct agtcttaaat aagatgtgag agggagtttt atgtttaaag ttttacaaaa
    89641 agttggaaaa gcttttatgt tacctatagc tatacttcct gcagcaggtc tacttttggg
    89701 gattggtggt gcactttcaa acccaaccac gatagcaact tatccaatac tagacaatag
    89761 tatttttcaa tcaatattcc aagtaatgag ctctgcagga gaggttgtat tcagtaattt
    89821 gtcactactt ctctgtgtgg gattatgtat tggcttagcg aaacgagata aaggaaccgc
    89881 tgcgttagca ggagtaactg gttacttagt tatgactgca acgatcaaag ctttggtaaa
    89941 actttttatg gcagaaggat ctgcaattga tactggagtt attggagcat tagttgtcgg
    90001 aatagttgcc gtatatttgc acaaccgata taacaatatt caattacctt ccgctttagg
    90061 attctttgga ggttcacgct tcgttcctat tgttacatcg ttctcttcta tcttgattgg
    90121 ctttgtcttc tttgttattt ggccaccttt ccaacaactt cttgtttcta caggtggata
    90181 tatttctcag gcgggtccaa ttggaacttt tctatatgga tttttaatga gactttctgg
    90241 agcagtaggc ttacatcata taatttaccc tatgttttgg tatactgaac ttggtggtgt
    90301 tgaaactgtt gcaggacaaa cagtggttgg agctcaaaaa atattttttg ctcaattagc
    90361 cgatttggcc cattctggat tatttacaga aggaacaagg ttttttgcag gtcgtttctc
    90421 aacaatgatg ttcggtttac cggctgcctg tttagcgatg taccatagtg ttcctaaaaa
    90481 tcgtcgtaaa aaatacgcgg gtttgttttt tggagttgct ttaacatctt ttattaccgg
    90541 tattacagaa ccaattgaat ttatgtttct attcgtcagt ccggttctat atgttgttca
    90601 cgcattcctt gatggtgtta gcttctttat tgcagacgtc ttaaatattt caataggaaa
    90661 cacattttca ggaggtgtaa tcgatttcac tttatttgga attttgcagg ggaacgctaa
    90721 gacgaattgg gttcttcaga ttccatttgg acttatttgg agtgttttgt attatattat
    90781 ttttagatgg ttcattactc aattcaacgt tctaacgcca ggacgaggag aagaagtaga
    90841 ttctaaagaa atttctgaat ccgcagattc aacttcaaat actgcagatt atttaaaaca
    90901 ggatagccta caaattatca gagccttggg tggatcaaat aatatagaag atgtagatgc
    90961 ttgtgtgaca cgtttacgtg tagctgtaaa agaagttaat caagttgata aagcactttt
    91021 aaaacaaatt ggtgcagttg atgtcttaga agtgaagggt ggcattcaag caatatatgg
    91081 agcaaaagca atcttatata aaaatagtat taatgaaatt ttaggtgtag atgattaagt
    91141 acttactgac ttaataaaaa acagaggaga gtgatggatg agtaggatga aatgaaatcg
    91201 catacaagaa ataaagaact cattatccaa gttggatacg cttattacat aggagaatac
    91261 aaatgaaatt tagaaaatta gcttgtacag tacttgcggg tgctgcggtt cttggtcttg
    91321 ctgcttgtgg caattctggc ggaagtaaag atgctgccaa atcaggtggt gacggtgcca
    91381 aaacagaaat cacttggtgg gcattcccag tatttaccca agaaaaaact ggtgacggtg
    91441 ttggaactta tgaaaaatca atcatcgaag cgtttgaaaa agcaaaccca gatataaaag
    91501 tgaaattgga aaccatcgac ttcaagtcag gtcctgaaaa aatcacaaca gccatcgaag
    91561 caggaacagc tccagacgta ctctttgatg caccaggacg tatcatccaa tacggtaaaa
    91621 acggtaaatt ggctgagttg aacgacctct tcacagatga atttgttaaa gatgtcaaca
    91681 atgaaaacat cgtacaagca agtaaagctg gagacaaggc ttatatgtat ccgattagtt
    91741 ctgccccatt ctacatggca atgaacaaga aaatgttaga agatgctgga gtagcaaacc
    91801 ttgtaaaaga aggttggaca actgatgatt ttgaaaaagt attgaaagca cttaaagaca
    91861 agggttacac accaggttca ttgttcagtt ctggtcaagg gggagaccaa ggaacacgtg
    91921 cctttatctc taacctttat agcggttctg taacagatga aaaagttagc aaatatacaa
    91981 ctgatgatcc taaattcgtc aaaggtcttg aaaaagcaac tagctggatt aaagacaatt
    92041 tgatcaataa tggttcacaa tttgacggtg gggcagatat ccaaaacttt gccaacggtc
    92101 aaacatctta cacaatcctt tgggcaccag ctcaaaatgg tatccaagct aaacttttag
    92161 aagcaagtaa ggtagaagtg gtagaagtac cattcccatc agacgaaggt aagccagctc
    92221 ttgaatacct tgtaaacgga tttgcagtat tcaacaataa agacgacaag aaagtcgctg
    92281 catctaagaa attcatccag tttatcgcag atgacaaaga gtggggacct aaagacgtag
    92341 ttcgtacagg tgctttccca gtccgtactt catttggaaa actttatgaa gacaaacgca
    92401 tggaaacaat cagcggctgg actcaatact actcaccata ctacaacact attgatggtt
    92461 ttgctgaaat gagaacactt tggttcccaa tgttgcaatc tgtatcaaat ggtgacgaaa
    92521 aaccagcgga tgctttgaaa gccttcactg aaaaagcaaa cgaaacaatc aaaaaagcta
    92581 tgaaacaata gtccttagtt attctataaa aagtagtttt ttaaagaacc taagagtgta
    92641 tacccccttt tccctctaca cagatagtgt aagaaaaggg ggcttttgtt taaaatgtaa
    92701 gaaactgtca cgaaattaaa atgaagttct tacataagcg aatcataaaa aatttcattt
    92761 tgattttaaa acagttcaag aaagtcaaaa aattattcta tttgaaagag aggtgccgac
    92821 tgtgaaagtc aataaaatcc gtatgcggga aacagtgatt tcctacgctt tcctagcacc
    92881 agtattattc ttctttgtca tctttgtgtt ggctccgatg gtgatgggct tcattacaag
    92941 tttctttaac tactcaatga ctaaatttga gtttgtaggc ttggataact atatccgtat
    93001 gtttaaagat cctgtcttta caaaatctct gattaacaca gttattttgg ttattggatc
    93061 tgtaccagtt gttgttctat tctcactctt tgtagcatct cagacctatc atcaaaatgt
    93121 cattgccaga tccttctacc gtttcgtctt cttccttcct gttgtaacgg gtagtgttgc
    93181 cgtgacagtt gtttggaaat ggatttatga cccgctatca gggattctaa actttgtcct
    93241 taagtcaagc cacatcatca gccaaaacat ttcttggttg ggagataaaa actgggcatt
    93301 gatggcgatt atgattattc tcttgaccac ttcagttggt cagcccatca tcctttatat
    93361 cgctgccatg gggaatattg acaattcact ggttgaagcg gcgcgtgttg atggtgcaac
    93421 tgagtttcaa gttttttgga agattaaatg gccaagcctt cttccaacaa ctctttatat
    93481 tgcaatcatc acaacaatta actcattcca gtgtttcgcc ttgattcagc ttttgacatc
    93541 tggtggtcca aactactcaa caagtacctt gatgtactac ctttacgaaa aagccttcca
    93601 attgacagaa tacggctatg ccaacacaat tggtgtcttc ttggcagtca tgattgctat
    93661 cgtaagcttt gttcaattta aagtacttgg aaacgacgta gaatactaaa gaaaggagac
    93721 agctatgcaa tctacagaaa aaaaaccatt aacagccttt actgttattt caacaatcat
    93781 tttgctcttg ttgactgtgc tgttcatctt tccattctac tggattttga caggggcatt
    93841 caaatcacaa cctgatacaa ttgttattcc tcctcagtgg ttccctaaaa tgccaaccat
    93901 ggaaaacttc caacaactca tggtgcagaa ccctgccttg caatggatgt ggaactcagt
    93961 atttatctca ttggtaacca tgttcttagt ttgtgcaacc tcatctctag caggttatgt
    94021 attggctaaa aaacgtttct atggtcaacg cattctattt gctatcttta tcgctgctat
    94081 ggcgcttcca aaacaagttg tccttgtacc attggtacgt atcgtcaact tcatgggaat
    94141 ccacgatact ctctgggcag ttatcttgcc tttgattgga tggccattcg gtgtcttcct
    94201 catgaaacaa tttagtgaaa atattcctac agagttgctt gaatcagcta aaatcgacgg
    94261 ttgtggtgag attcgtacct tctggagtgt agccttcccg attgtgaaac cagggtttgc
    94321 agcccttgca atctttacct tcatcaatac ttggaatgac tacttcatgc aattggtaat
    94381 gttgacttca cgtaacaatt tgaccatctc acttggggtt gcgaccatgc aggctgaaat
    94441 ggcaaccaac tatggtttga ttatggcagg agctgccctt gctgctgttc caatcgtcac
    94501 agtcttcctt gtcttccaaa aatccttcac acagggtatt actatgggag cggtcaaagg
    94561 ataatactct gcgaaaatct cttcaaacta cgtcagcttc accttgccat acttaagtat
    94621 tgcctgcggt tagcttccta gtttgttctt caattttcat tgagtatagg aaaatcaatc
    94681 tatcaagata cagaagtata ttttatagat ttagagaata tagaggttat aagtgtctac
    94741 aaaatggagg gtatgcagtt actttatgaa gttttgtcag acacttatca acttaagaat
    94801 ggttttagtt aactatcaga aacgaaggaa agagtatgat ttttgacgat ttgaaaaaca
    94861 tcacctttta caaagggatt tatcctaatt tagacaaggc tatcgactat ctctaccaac
    94921 atcgtaagga ttctttcgaa ttaggaaagt atgatattga tggagataaa gtctttctag
    94981 ttgttcagga aaatgtcctc aatcaagctg aaaatgatca atttgagtat cataagaact
    95041 atgcagattt gcatttgctg atagaagggc atgaatattc gagctacggt tcacgtatca
    95101 aagacgaggc agtagcattc gacgaagcga gtgacattgg ctttgttcat tgttatgaac
    95161 actacccact cttattgggt tatcacaatt ttgcgatttt cttcccaggt gagccacatc
    95221 agccaaatgg ttatgcaggc atggaagaaa aggttcgaaa atatctcttt aaaatcttga
    95281 ttgattaaaa ataggatgaa ttgttttttt gtaaagcttt gataatactc taccatgaaa
    95341 ttgatctttg tgaggtagag aaatgagaat aaaatattta aaaattggta tcttctaagt
    95401 atgctgcaag agctagtttc ttggatggac agggaattac agttgatgag atggcttgga
    95461 taattagggg cattgtgaat gcattgattg gtagatacat aaaattaggt gcttatgcgg
    95521 ctaagtatgg tattagtatg gcacgctcga tcttaagtag ggcagctgca actgcggcag
    95581 caagagtagg attattgacc aagatttttg gatggatttt acgaatagct gtgctcgcag
    95641 ctgatgtata tggtaatttt gccaacaata ttgctgcagc ttgggatgca tatgataaaa
    95701 ttcctaacaa tggtcgtata aacttttaaa atgcgagaat gaaagcactt tgtatttttt
    95761 tattgaatat gttagcttgg acagtgcttg caatgataat tcgtggaggg ctagatggat
    95821 ttaatgagca tacttggagt actattttaa ttgcttcgct gtccgggata tatatagatt
    95881 atatgtccat agataaaagt agaaaaaagt ccaaaagaaa aaagaaaaaa tagatttgtt
    95941 catggtaggg acttatgaaa gttttactga caaaaaagaa aacagtttac aaagaaaaat
    96001 gatggaggag caaacatggc acaaaaagga gtaagcctta tcaaggcagc atttgataca
    96061 gataactttc tcatgcgttt tagtgagaaa gtcttggaca tcgtgacagc caatcttctt
    96121 tttgtcgtct cttgtttgcc catcgtgacg attggagtgg ctaaaatcag cctctacgag
    96181 accatgttcg aagttaagaa gagcagacgg gtgcctgttt ttaaaatcta tctaagatct
    96241 ttcaagcaaa atctgaaact aggtcttcag ctgggtttaa tggagttagg aattgtgttt
    96301 cttacccttt cagatctcta tcttttctgg ggtcaaacag ctctgccctt ccaattgctg
    96361 aaagccattt gtttaggtat tctgattttt cttactatcg tgatgctggc tagttaccct
    96421 atcgcggcac gttatgacct atcttggaaa gaaattcttc aaaaaggatt gatgttggct
    96481 agttttaact ttccttggtt cttcctcatg ttagccattc ttgtcctcat tgtgatggtt
    96541 ctttatctgt ccgccttcag tctactctta ggtggctcag tcttcctact ttttgggttt
    96601 ggactattgg tctttatcca gactggattg atggagaaaa ttttcgcaaa ataccaatag
    96661 gagctttatt tctgaaacta ctttcaaagg ctccaaacgc tattctataa gcgagaaact
    96721 aaaatctaag tgtctataag atattgaaag ccttttcggt aaagtgtata ctaaagaagt
    96781 aaagaaaaat ctgctttagc agaaaataaa aataatagga gaaaatctat gtcagatttg
    96841 aaaaaatacg aaggtgtcat tccagccttc tacgcatgtt atgatgatca aggagaagta
    96901 agcccagaac gtacgcgtgc cttggttcaa tacttcattg ataaaggtgt tcaaggtctt
    96961 tatgtcaatg gttcttctgg tgaatgtatc taccaaagcg ttgaagatcg caagttgatt
    97021 ttggaagaag tcatggcggt agccaaaggt aaattgacca ttattgccca tgttgcttgc
    97081 aataatacta aagatagtat ggaacttgct cgccatgctg aaagcttggg agtagatgct
    97141 attgcaacga ttccaccaat ttacttccgc ttgccagaat actcagttgc taaatactgg
    97201 aacgatatta gttctgcagc tccaaataca gactacgtga tttataacat tcctcaattg
    97261 gcaggggttg ctttgactcc aagcctttac actgaaatgt tgaaaaatcc tcgtgttatc
    97321 ggtgtgaaga actcttctat gccagttcaa gatatccaaa cctttgtgag ccttggtggg
    97381 gaagaccata tcgtctttaa cggtccagat gaacagttcc taggtggccg cctcatgggt
    97441 gccaaagctg gtatcggtgg tacttatggt gctatgccag aactcttctt gaaactcaat
    97501 cagttgattg cggataagga cctagaaaca gcgcgtgaat tgcagtatgc tatcaacgct
    97561 atcattggta aattgactgc tacacatgga aatatgtacg gtgtcatcaa agaagttttg
    97621 aagatcaatg aaggcttgaa tattggttct gttcgttcac cattgacacc agtgactgaa
    97681 gaagatcgtc cagttgtaga agcggctgct gccttgattc gtgaaaccaa ggagcgcttc
    97741 ctctaatcta aaaggaggta tttatgacat actacgttgc aattgatatc ggtggaacca
    97801 acatcaagta tggtttggtt gatcaagagg ggcaacttct tgaatcgcat gaaatgccaa
    97861 ctgaggcgca taagggtgga cctcatatct tacaaaagac caaagatatc gtagctagtt
    97921 atttagaaaa aggcccagta gcaggtgttg ccatatcttc tgctgggatg gtggatccgg
    97981 ataagggtga gattttctat gctgggccgc aaatccctaa ctacgcaggc acccagttca
    98041 aaaaggaaat cgaagaaagc tttactattc cttgtgagat tgaaaatgat gtcaactgtg
    98101 caggtcttgc tgaggcagta tctggttcag gcaagggagc aagtgtgaca ctttgcttga
    98161 ccattggaac aggtatcggt ggttgcttga ttatggatag gaaagtcttc catggtttta
    98221 gcaattcagc ctgtgaagtc gggtatatgc atatgcagga tggagctttt caagacttgg
    98281 cttctacaac agctttagtg aaatatgtag ctgaagccca tggagaagat gttgatcagt
    98341 ggaatggccg tagaattttc aaagaagcca ctgaaggaaa caaaatctgc atggaaggta
    98401 ttgaccgtat ggttgactat ctaggaaaag gtctggcaaa tatttgctac gttgccaatc
    98461 cagaagtggt tattcttggt ggtggtatca tggggcaaga ggctatcctc aaacctaaga
    98521 tccgcacagc cttgaaagag gctttggtac caagtttagc agaaaaaaca cgattagaat
    98581 ttgcccatca ccaaaataca gcagggatgt tgggtgcata ttatcatttt aagacaaaac
    98641 aatcctagtt tggctcagcc aaactaggat tttcttacac gtttttgtct acgatagccg
    98701 ttgagttttt tattttccca gtagctatta aagatttttt ccttgctttc gcgattgatt
    98761 tccaaaaagt aggcataaat caaatcgata aagaagagca taggaagttg agcggatatt
    98821 cgttggatat aggaggtttg gctatgggtg gctacaagaa cagtctctgt ataggtctgg
    98881 ctatctttat tgggaacact tgtaaagagt acagtctttg cccccatctc cttggcatct
    98941 aatagactat ctaaaataga aggagttgag cctgaaagtg agaaacccag tactagacaa
    99001 ttttcatcca tgatgctggt tgtccaggca aagccgtctt ggtctgtcaa agcttcgcag
    99061 accacaccta gtcgcataaa acgtaatttc atttcacggg cgacgaggcc agaactccct
    99121 gttccaaaga agtagatacg ctcagcatct tcgattagct gggcaattcg ctctagttgg
    99181 atttcgtcaa tcaagtcttg tgtttgttcc ctcatattgc tataacttct gaggactcgt
    99241 ttggtcagtg gactatgctt ggagacttgg ttggcttgat tttctgcctg atgttggtat
    99301 tggaaaataa attctcggta gccagtaaag ccacactttt tagcaaagcg ggtcaaagca
    99361 gcttgagaaa tatgtaattt ttgggtgact tgttgagaag ataaatcatc tgtaatcgtt
    99421 tcagcttgca aaaaatagcg agcgatttct tgctctaggt ctgtcatttc ttcaaaatgt
    99481 gaatcaatga tagttgcgat atctggtttg tccataggga aagctccttt acatgagtca
    99541 tactggaaga ctagatcagg gaatagtcac acttcattat aacacataat ataaggatag
    99601 ataaataaaa acacatctct gttttaaaaa cgaaaaaatc gaaaaagctt ctttcttttc
    99661 cataattttc tactcaaatt gtggtacaat taagagtaag attttaagtt agaaatgaga
    99721 ctgatttgta tgagaaaatt taacagccat tcgattccga ttcggcttaa tttattgttt
    99781 tcaatcgtca ttttactctt tatgaccatt attggtcgtt tgttgtatat gcaggttttg
    99841 aacaaggatt tttacgaaaa aaagctagct tcagctagtc agaccaagat tacaagcagt
    99901 tcagcccgtg gggaaattta tgatgctagt ggaaaacctt tggtagaaaa tacgttaaag
    99961 caggttgttt cctttacgcg tagcaataaa atgacggcta cagacttaaa agaaacagct
   100021 aaaaagttac tgacttatgt gagcatcagt tctccaaatt tgacagaacg ccagctggcg
   100081 gattactatt tggctgatcc tgaaatctat aaaaaaacag tggaagctct cccaagcgag
   100141 aaacgcttgg gttcagatgg caatcgtcta tccgaatcag aactgtataa caatgcggtc
   100201 gatagtgtcc aaacaagtca actaaactat acagaggatg aaaagaaaga aatctatctt
   100261 tttagtcagt taaatgctgt tggaaacttt gcgacaggaa ccattgcgac agatcctcta
   100321 aatgattctc aggtggctgt tattgcctct atttcaaagg agatgcctgg cattagtatt
   100381 tctacttctt gggatagaaa ggttttggaa acttcccttt cttctatagt tgggagtgta
   100441 tccagtgaaa aagctggtct cccagcggaa gaagcagaag cctatcttaa aaaaggctat
   100501 tctctaaatg atcgtgtagg aacctcctat ttggaaaagc aatatgaaga gaccttacaa
   100561 ggaaaacgct cggtaaaaga aatccatctg gataaatatg gcaatatgga aagcgtggat
   100621 acaattgagg aaggtagtaa gggaaacaat atcaaactga ccattgattt ggcattccaa
   100681 gatagcgtgg atgctttact gaaaagttat ttcaattccg agctagaaaa tggtggagcc
   100741 aagtattctg aaggtgtcta tgcagtcgcc cttaacccaa aaacaggtgc ggttttgtct
   100801 atgtcaggga ttaaacatga cttgaaaacg ggagagttga cgcctgattc cttgggaacg
   100861 gtaaccaatg tctttgttcc aggttcggtt gtcaaggcgg cgaccatcag ctcaggttgg
   100921 gaaaatggag tcttgtcagg aaaccagacc ttgacagacc agtccattgt cttccaaggt
   100981 tcagctccca tcaattcttg gtatactcag gcttacggtt cattccctat cacagcggtc
   101041 caagctctgg agtattcatc taatacctat atggtccaaa cagccttagg tcttatgggg
   101101 caaacctatc aacccaatat gtttgtcggc accagcaatc tagagtctgc tatggagaaa
   101161 ctgcgttcaa cctttggcga atatggcttg ggtactgcga caggaattga cctaccagat
   101221 gaatctactg gatttgttcc caaagagtat agctttgcta attacattac taatgccttt
   101281 gggcagtttg ataactatac gccgatgcag ttggctcagt atgtagcaac tattgcaaat
   101341 aatggtgttc gtgtggctcc tcgtattgtt gaaggcattt atggtaataa tgataaggga
   101401 ggactgggtg acttgattca gcaactgcaa ccgacagaga taaataaggt caatatatcc
   101461 gactccgata tgagcatctt gcaccaaggt ttttatcagg ttgcccatgg tactagtgga
   101521 ttgacaactg gacgtgcctt ttcaaatggt gccttggtat ccattagcgg aaaaacaggt
   101581 acagccgaaa gctatgtggc agatggtcag caagcaacca ataccaatgc ggtggcctat
   101641 gccccatctg ataatcccca aatcgctgtc gcagtggtct ttcctcataa taccaatcta
   101701 acaaatggtg taggaccttc cattgcgcgt gacattatca atctgtatca aaaataccat
   101761 ccaatgaact agaaaggaaa ttatgcttta tccaacacct attgccaagt tgattgacag
   101821 ttattctaag ttaccaggta tcgggattaa gacggctacg cgtctggcct tttatacgat
   101881 tgggatgtct gctgatgatg tcaatgaatt tgcaaaaaat ctcctttctg ctaagagaga
   101941 attgacatat tgttctattt gtggacgttt gacagacgac gatccttgtt ctatctgtac
   102001 tgattcgact cgtgaccaga caacaatttt agttcttgag gatagtagag atgtggcagc
   102061 catggaaaat atccaagaat accatggact ctatcatgtc ctgcatggcc tcatttctcc
   102121 tatgaatggt atcagtccgg acgatatcaa tcttaagagc cttatgactc gtcttatgga
   102181 tagtgaggtt tcagaagtga ttgtggcgac taatgctaca gcggatggtg aagcgacctc
   102241 catgtatctt tcacgtttgc tcaagccggc tggtatcaag gttacgcgtc tagcacgagg
   102301 tctcgctgtg ggagcggaca ttgagtatgc ggacgaagtg acactcttac gagcgattga
   102361 aaatcggaca gagttgtaag tgtaggcaaa tttacgaact ccattcattt ataaaaaatc
   102421 aaagaggctg aaaatcgttc ctatcggcct ctttttgtat agtgtgatga gtagaatcag
   102481 gttcaagttt taaaaaacca agcaaatatg atatactaaa gagcgagtat tctagtagaa
   102541 ttaggacaaa taatatgaaa caaacgatta ttcttttata tggtggacgg agtgcggaac
   102601 gcgaagtctc tgtcctttca gctgagagtg tcatgcgtgc ggtcaattac gaccgtttca
   102661 cagtcaagac tttctttatc agtcagtcag gtgactctat caaaacgcag gaatttagtc
   102721 atgctccggg gcaagaagac cgtctcatga ccaatgaaac cattgattgg gataagaaag
   102781 ttgcaccaag tgctatctac gaagaaggtg cagtggtctt tccagtcctt cacgggccaa
   102841 tgggagaaga tggctctgtt caaggattct tggaagtttt gaaaatgcct tacgttggtt
   102901 gcaacatttt gtcatcaagt cttgccatgg ataaaatcac gactaagcgt gttctggaat
   102961 ctgctggtat tgcccaagtt ccttatgtgg ctatcgttga aggcgatgat gtgactgcta
   103021 aaatagctga agtggaagaa aaattggctt atccagtctt cactaagccg tcaaacatgg
   103081 ggtctagtgt cggtatttct aagtctgaaa accaagaaga actccgtcaa gccttaaaac
   103141 ttgccttccg atatgacagc cgtgtcttgg ttgagcaagg agtgaatgcc cgtgaaattg
   103201 aggttggcct cttgggtaac tacgatgtca agagcacgct acctggagaa gttgtcaagg
   103261 acgttgcctt ttatgactac gatgccaagt atattgataa caaggttact atggatattc
   103321 ctgccaaaat cagtgatgat gtggtggctg tcatgcgtca aaatgcagaa acagccttcc
   103381 gtgccattgg tggccttggt ctatctcgtt gcgatttctt ctatacagat aagggagaga
   103441 tttttctcaa cgagctcaat accatgccag gtttcaccca gtggtctatg tacccactac
   103501 tttgggaaaa tatggggatc agctacccag aactaatcga gcgtttggtt gaccttgcca
   103561 aggaaagttt tgacaagcgc gaagcgcatt tgatataaaa tgaaagagag ggtagaagcc
   103621 agaaccatca ctgcaaggtg actagagttc tcggacttca gcccttttta aaggagtaga
   103681 aatgaaatta acaatccatg aaattgccca agttgttgga gccaaaaatg atatcagtat
   103741 ctttgaggac actcagttag aaaaagctga gtttgatagt cgtttgattg gaactggaga
   103801 tttatttgtg ccacttaaag gtgcgcgtga tggccatgac tttattgaaa cagcctttga
   103861 aaatggtgca gcagtaacct tgtctgagaa agaggtctca aatcatcctt acattttagt
   103921 agatgatgtt ttgacagcct ttcaatccct agcatcctac tatcttgaaa aaacgactgt
   103981 tgatgtcttt gctgttacag gttcaaatgg caagacaacg actaaggata tgttggcgca
   104041 tttactgtca acaagataca agacctacaa aacacaaggc aattacaata atgagattgg
   104101 ccttccttac acagttcttc atatgcctga aggaacagaa aagttggttt tggagatggg
   104161 acaggatcac ttgggagata ttcatctctt gtctgaattg gctcgtccaa aaacagccat
   104221 cgtgaccttg gttggagaag ctcatttggc ctttttcaaa gatcgttctg agattgctaa
   104281 aggaaaaatg caaattgcag acggaatggc ttcaggttcc ttgcttttag cgccggctga
   104341 ccctatcgta gaggactatt tgccaattga taaaaaggtg gttcgttttg gtcaaggagc
   104401 agagctggaa attactgact tggttgagcg taaggacagt ctgaccttta aggctaattt
   104461 cttggaacaa gcccttgatt tgccagtaac tggcaagtac aatgcgacaa atgctatgat
   104521 tgcatcctat gttgccttgc aagaaggagt ttcagaggag caaattcgtt tggcattcca
   104581 acatcttgaa ttgacgcgta accgtaccga gtggaagaaa gcagccaatg gagcagatat
   104641 cctgtcagat gtttacaatg ccaatccaac tgctatgaaa ctgattttag agactttctc
   104701 tgccattcca gccaatgaag gtggcaagaa aattgcagtg ttggcggata tgaaggagct
   104761 tggtgaccag tctgttcaac ttcataatca gatgattttg agcctctccc cagatgtgct
   104821 tgatatcgtt attttctatg gagaagatat tgctcagttg gctcaattgg ccagtcaaat
   104881 gtttccaatc ggccacgttt actacttcaa gaaaacagaa gaccaggatc aatttgaaga
   104941 cctagtcaag caggttaagg aaagccttgg agcctatgac caaatcttgc taaaaggttc
   105001 taactctatg aatctagcca aattggtaga aagtttagaa aatgaatgca agtgattttg
   105061 ctaagtatct tcaaagaatg attgctctta cagatactgg actaaccttt acaaaggatc
   105121 cgtttgaccg tgagcgctac gaagacttgc gaagtctgtt atctgaaatg ttgaatcagg
   105181 tatcagacct ggatgcagac gaagtggcag aactcttgaa accgacctcc gcttatgcga
   105241 ctcctttaat ggacgtccgt gcttggatag ttgaggatga aaaaatttgt ctggttaggg
   105301 gacaaggaga gaatgattgg gctttgccag gtggctttgg cgaggtcggt tattcaccaa
   105361 ctgaaaatat tctcaaggaa attgaagaag aaaccggttt taaagccaaa gttgaacgac
   105421 tactagctgt ttttgatacc aatcgtttcc aactacagag caaacaatat gcaaagtttg
   105481 tttttgaatg taagcttctc gatggacaat ttcaagaaaa tcaagaaatc gctgaccttc
   105541 aattttttgc aattgaccaa ctgccgaatt tatctgaaaa acgcattacc aaggagcaaa
   105601 tagagcttct ttggcaggtt tatcaaggtc atagggggca atatcttgac taagaagatg
   105661 attatcgtat ttctaaatcc atttttaaca actagcatgg tataataata tgcaggaaaa
   105721 ttttgaatta tgaggaagac tagatgaatt tatgggatat tttctttacg actcaggcaa
   105781 ccgagccgcc caaatttgac cttttttggt atgttagcct atttacgctc ttagccttaa
   105841 ccttttatac agcccatcgc tatcgtgaaa ataaggttta ccaacgattt ttccaaatct
   105901 tgcagactgt tcagttaatc cttctttatg gttggtactg ggtcaatcat atgccactgt
   105961 cagaaagcct acccttttac cattgccgta tggctatgtt tgtggtactc ttgcttcctg
   106021 gtcaatccaa atataaacaa tactttgcat tattgggaac atttgggaca ttagcagcct
   106081 ttgtttatcc agtgccagat gcttaccctt ttccacatat caccattcta tcctttatct
   106141 ttggtcattt agcactcttg gggaactctc tagtttatct attgagacag tataatgcgc
   106201 gattgctgga tgtgaaggga atttttctca tgacctttgc cctaaatgcc ttgatttttg
   106261 tggtcaattt ggtgacaggt ggcgattacg gatttttgac aaaaccgcca ttggttgggg
   106321 atcacggtct agtagctaat tatttacttg tttcaattgt gctggtagct actatcagtt
   106381 tgactaagaa aatcttagaa ttctttttag ctcaagaagc agaaaaaatg attgcaaagg
   106441 aagcttaaca cagagctttc ttttttgctc ttagagagtt tttacaagca gcttataaaa
   106501 taagaatttc tgaatagaca aactcaaaaa atggctggga aatttaggaa aaaagcaagc
   106561 acgattaaat tttttgtgtt ataatatttt gtgaatagct atgcctatgt ttagctatgg
   106621 aataatacga agtgcgaaac ttggaagata gagaggaagc gatgtaatgg ctagagaagg
   106681 cttttttaca ggtctagata ttggaacaag ctctgtcaag gtgcttgtgg ccgagcagag
   106741 aaatggtgaa ttaaatgtaa ttggcgtgag taatgccaaa agtaaaggtg taaaggatgg
   106801 aattattgtt gatattgatg cagcagcaac tgctatcaag tcagccattt cccaagcgga
   106861 agaaaaggca ggcatttcga ttaaatcagt gaatgtcggc ttgcctggta atcttttgca
   106921 ggtagaacca actcagggga tgattccagt aacatctgat actaaggaaa ttacggatca
   106981 agatgttgaa aatgttgtca aatcagcttt gacaaagagt atgacacctg accgtgaagt
   107041 cattaccttt attcctgaag aatttattgt ggatggtttc caagggattc gtgacccacg
   107101 tggcatgatg ggggttcgcc ttgaaatgcg tggtttgctt tatacaggac ctcgtactat
   107161 cttgcacaat ttgcgtaaga cggttgagcg tgcaggtgtt caggttgaaa atgttatcat
   107221 ttcaccacta gcaatggttc agtctgtttt gaacgaaggg gaacgtgaat ttggtgctac
   107281 agtgattgat atgggggcag gtcaaacgac tgtcgctaca atccgtaatc aagaactcca
   107341 gttcacacat attctccaag aaggtggaga ttatgtaact aaagatatct ccaaggtttt
   107401 gaaaacctct cgcaaattag cggaaggctt gaaactgaat tacggggaag cctatccgcc
   107461 tcttgcaagc aaagaagcct tccaagtaga ggttattgga gaagtagaag cagtcgaagt
   107521 gacggaagcc tacttgtcag aaattatttc tgcacgaatc aagcacatcc ttgaacaaat
   107581 caagcaagaa ttagatagaa ggcgtctatt ggacctccct ggtggtattg tcttaatcgg
   107641 tgggaatgcc attttaccag gtatggttga gcttgctcag gaagtctttg gcgtccgtgt
   107701 caagctttat gttccaaatc aagttggtat ccgtaatcca gcctttgcgc atgtgattag
   107761 tttatcagaa tttgcgggtc aattaacaga agttaatctt ttggctcagg gagcgataaa
   107821 aggtgagaat gacttaagtc atcagccaat tagttttggt gggatgctgc aaaaaacagc
   107881 tcagtttgta caatcaacgc ctgttcaacc agctcctgct ccagaagtag agctggtggc
   107941 gcctacagaa ccaatggcgg atttccaaca agcttcacaa aataaaccga aattagcaga
   108001 tcgtttccgt ggcttgatcg gaagcatgtt tgacgaataa agaggaaaaa taaattatga
   108061 cattttcatt tgatacagct gctgctcaag gggcagtgat taaagtaatt ggtgtcggtg
   108121 gaggtggtgg caatgccatc aaccgtatgg tcgacgaagg tgttacaggc gtagaattta
   108181 tcgcagcaaa cacagatgta caagcattga gtagtacaaa agctgagact gttattcagt
   108241 tgggacctaa attgactcgt ggtttgggtg caggaggtca acctgaggtt ggtcgtaaag
   108301 ccgctgaaga aagcgaagaa acactgacgg aagctattag tggtgccgat atggtcttca
   108361 tcactgctgg tatgggagga ggctctggaa ctggagctgc tcctgttatt gctcgtatcg
   108421 ccaaagattt aggtgcgctt acagttggtg ttgtaacacg tccctttggt tttgaaggaa
   108481 gtaagcgtgg acaatttgct gtagaaggaa tcaatcaact tcgtgagcat gtagacactc
   108541 tattgattat ctcaaacaac aatttgcttg aaattgttga taagaagaca ccgcttttgg
   108601 aggctcttag cgaagcggat aacgttcttc gtcaaggtgt tcaagggatt accgatttga
   108661 ttaccaatcc aggattgatt aaccttgact ttgccgatgt gaaaacggta atggcaaaca
   108721 aagggaatgc tcttatgggt attggtatcg gtagtggaga agaacgtgtg gtagaagcgg
   108781 cacgtaaggc aatctattca ccacttcttg aaacaactat tgacggtgct gaggatgtta
   108841 tcgtcaacgt tactggtggt cttgacttaa ccttgattga ggcagaagag gcttcacaaa
   108901 ttgtgaacca ggcagcaggt caaggagtga acatctggct cggtacttca attgatgaaa
   108961 gtatgcgtga tgaaattcgt gtaacagttg tcgcaacggg tgttcgtcaa gaccgcgtag
   109021 aaaaggttgt ggctccacaa gctagatctg ctactaacta ccgtgagaca gtgaaaccag
   109081 ctcattcaca tggctttgat cgtcattttg atatggcaga aacagctgaa ttgccaaaac
   109141 aaaatccacg tcgtttggaa ccaactcagg catctgcttt tggtgattgg gatcttcgcc
   109201 gtgaatcgat tgttcgtaca acagattcag tcgtttctcc agtcgagcgc tttgaagccc
   109261 caatttcaca agatgaagat gaattggata cacctccatt tttcaaaaat cgttaagtaa
   109321 atgaatgtaa aagaaaatac agaacttgtt tttcgagaag ttgcagaggc tagtctgagt
   109381 gctaatcgag agcgtggttc ggtctctgtc attgcagtta ccaagtatgt agatgtaccg
   109441 acagcggaag ccttgcttcc gctaggtgtt catcatatcg gtgaaaatcg tgtagataag
   109501 tttctggaaa aatatgaagc tttaaaagat cgagatgtga cttggcattt gattggtacc
   109561 ttgcaaagac gtaaggtgaa agatgtcatt caatacgttg attatttcca tgcattggac
   109621 tcagtaaagc tagcagggga aattcaaaaa agaagtgacc gagtcatcaa gtgtttcctt
   109681 caagtaaata tttctaaaga agaaagcaaa cacggttttt cgagagagga actgctggaa
   109741 atcttgccag agttagccag actagataag attgaatatg ttggtttaat gacgatggca
   109801 ccttttgagg ctagcagtga gcagttgaaa gagattttca aggcgaccca agatttacaa
   109861 agagaaattc aagagaaaca aattccaaat atgcctatga ccgagttaag tatgggaatg
   109921 agtcgtgatt ataaagaagc gattcaattc ggttccactt ttgttcgtat aggtacatca
   109981 ttttttaagt aggagagaac catgtcttta aaagatagat tcgatagatt tatagattat
   110041 tttacggagg atgaggattc aagtctccct tatgaaaaaa gagatgagcc tgtgtttact
   110101 ccagtaaatt cttcacagga accggctctc ccaatgaatc aaccttcaca gtcggctggt
   110161 acaaaagaga acaatatcac cagacttcat gcaagacaac aggaattggc aaatcagagt
   110221 cagcgtgcaa cggataaggt cattatagat gttcgttatc ctagaaaata tgaggatgca
   110281 acagaaattg ttgatttatt ggcaggaaac gaaagtatct tgattgactt tcagtatatg
   110341 acagaggtgc aggctcgtcg ttgtttggac tatttggatg gagcttgtca tgttttagct
   110401 ggaaatttga aaaaggtagc ttctaccatg tatttgttga caccagtgaa cgttattgta
   110461 aatgttgaag atatccgttt accagatgaa gatcaacagg gtgagttcgg ttttgatatg
   110521 aagcgaaata gagtacgata atgatttttt taattcgtat gatttataat gcagtggata
   110581 tttactccct gattttggta gccttcgctg tcatgtcttg gtttccaggt gcctacgaat
   110641 ccagtttagg tcgttggatt gtagcgttgg tgaaaccagt gcttgctccc ttgcaacgcc
   110701 tgcctttaca gatagcgggt cttgatttat ctgtttgggt tgcgattgtt ttggttcgat
   110761 ttttaggaga aaacctagtg cgttttctgg cgatgatagg atgaataaag ggatttatca
   110821 gcatttctcc atagaagatc gtccatttct tgacaaggga atggaatgga taaagaaggt
   110881 agaagatagc tatgctcctt ttttaactcc ttttatcaat cctcatcagg agaagctatt
   110941 aaagattttg gccaaaacct atggtcttgc ttgtagcagt agtggggaat tcgtctcgag
   111001 tgagtatgtt cgagttttat tatacccaga ttatttccaa ccagagtttt cagattttga
   111061 aatatctctc caggaaattg tgtattccaa taaatttgaa catttaacgc atgctaagat
   111121 tttagggaca gtcatcaatc aattagggat tgaacggaaa ctttttggag atatcctagt
   111181 agatgaagaa cgggcgcaga ttatgattaa tcagcagttt cttcttctct ttcaagatgg
   111241 actaaagaaa attggtcgta tacctgtttc gctggaggaa cgtcctttca ccgagaaaat
   111301 agataagcta gaacagtatc gagaactgga tttatctgtg tctagttttc gattagatgt
   111361 tcttttatca aatgttttga aactatctag gaatcaagca aaccagttga ttgaaaagaa
   111421 acttgtccaa gtaaattatc atgtggtaga caaatcagat tacactgttc aagttggaga
   111481 cttgattagt gtgagaaaat ttggtcgctt gagattactt caagataagg gacaaacgaa
   111541 aaaagagaag aaaaaaataa ccgtccagtt attattaagt aagtgaggaa tagaatgcca
   111601 attacatcat tagaaataaa ggacaagact tttggaactc gattcagagg ttttgatcca
   111661 gaagaagtcg atgaattttt agatattgtg gttcgtgatt acgaagatct tgtgcgtgcg
   111721 aatcatgata aaaatttgcg tattaagagt ttagaagagc gtttgtctta ctttgatgaa
   111781 ataaaagatt cattgagcca gtctgtattg attgcccagg atacagctga gcgagtgaaa
   111841 caggcggcgc atgaacgttc aaacaatatc attcatcaag cagagcaaga tgcgcaacgc
   111901 ttgttggaag aagctaaata taaggcaaac gagattcttc gtcaagcaac tgataatgct
   111961 aagaaagtcg ctgttgaaac agaagaattg aagaacaaga gccgtgtctt ccaccaacgt
   112021 ctcaaatcta caattgagag tcagttggct attgttgaat cttcagattg ggaagatatt
   112081 ctccgtccaa cagctactta tcttcaaacc agtgatgaag cctttaaaga agtggttagc
   112141 gaagtacttg gagaaccgat tccagctcca attgaagaag aaccaattga tatgacacgt
   112201 cagttctctc aagcagaaat ggaagaatta caagctcgta ttgaggtagc cgataaagaa
   112261 ttgtctgaat ttgaagctca gattaaacag gaagtggaaa ctccaactcc tgtagtgagt
   112321 cctcaagttg aagaagagcc tctgctcgtc cagttggccc aatgtatgaa gaaccagaag
   112381 tagctccagt gcatccgaca ggtccaacac cagctacaga aactgttgat tcagcaccgg
   112441 gatttgaagc accgcaagaa tctgttacaa ttttataaga aatattctga gaacaatatc
   112501 ttatccttat attcccagcg agcaggagat ggtgtgagtc ctgcattccc tatcgataag
   112561 attatcctct caaactatca agtctgaatc tagtaagatt tgacgttccc cacgttacgg
   112621 gataagaggg agaaagacta aaactttttc cgaataaagg tggtaccacg attttcgtcc
   112681 tttttggaag tcgtggtttt taatttgtta ttatttataa aggagatacc atgaaactaa
   112741 aagataccct taatcttggg aaaacagctt tcccaatgcg tgcaggcctt ccgaccaaag
   112801 agccagtttg gcaaaaggaa tgggaagatg caaaacttta ccaacgtcgt caagaactaa
   112861 atgaagggaa accgcatttt gtcttgcatg atggccctcc atacgcaaat ggaaatatcc
   112921 acgttggaca tgccatgaat catatctcaa aagatatcat cattcgttct aagtccatgt
   112981 caggttttaa ctcaccttat atcccaggtt gggatactca tggtctgcca atcgagcaag
   113041 ttttggcaaa gcaaggtgtt aagcgcaaag aaatggattt ggttgagtac ttgaaacttt
   113101 gccgtgaata cgctctttct caagtttata aacaacgtga tgatttcaag cgcttgggga
   113161 tgtcaggtga ctgggaaaat ttatatgtga ctttaactcc agactacgaa gcagcccaaa
   113221 tccgtgtatt tggtgagatg gctaataagg gttatatcta ccgtggtgct aagccagttt
   113281 actggtcttg gtcatctgag tcagcccttg ccgaagcgga aattgaatac catgatttgg
   113341 tttcaacttc cctttactat gccaataagg taaaagatgg caaaggtgtt ctagatacag
   113401 atacttatat cgttgtttgg acaactactc catttactat cacagcttct cgtggtttga
   113461 ctgttggtgc agatattgat tacgttttgg ttcaacctgc tggtgaaact cgtaagtttg
   113521 tcgttgctgc agaattgttg actagcttgt ctgagaaatt tggctgggtt gatgttcaag
   113581 ttttggcaac ttaccgtggt caagaactca accacatcgt aacagaacat ccatgggata
   113641 cagctgtaga tgaattggtt atccttggtg accacgttac aactgactct ggtacaggta
   113701 ttgtccatac agcccctggt tttggtgagg acgattacaa tgttggtatt gctaataatc
   113761 ttgaagtcgc agtgactgtt gatgaacgtg gtatcatgat gaagaatgct ggtcctgaat
   113821 ttgaaggtca attctatgaa aaggtagttc caactgttat tgaaaaactt ggtaacctcc
   113881 ttcttgccca agaagaaatc tctcactcat atccatttga ctggcgtacc aagaaaccaa
   113941 ttatctggcg tgcagtacca cagtggttcg cctctgtttc aaaattccgc caagaaatct
   114001 tggatgctat tgataaagtt aaattccata cagaatgggg taaagtacgt ctatataata
   114061 tgattcgtga ccgtggtgac tgggttatct ctcgtcaacg tgcttggggt gttccacttc
   114121 caatcttcta tgcagaagac ggtacagcta tcatgacagc tgagactatt gaacatgtgg
   114181 cgcaactctt tgaagtacat ggttcaagca tttggtggga acgtgatgcc aaggacctct
   114241 tgccagaagg atttacacat ccaggttctc caaatgggga gttcaagaaa gaaacagata
   114301 ttatggatgt atggtttgac tcaggttcat catggaatgg tgttttggta aatcgtccaa
   114361 atctgactta tccagctgac ctttaccttg aaggttctga ccaataccgt ggttggttca
   114421 actcatcact cattacatct gttgccaacc atggcgtagc accttacaaa caaatcttgt
   114481 cacaaggttt tgcccttgat ggtaaaggtg agaagatgtc taaatctctt ggaaatacca
   114541 ttgctccaag cgatgttgaa aaacaattcg gtgctgaaat cttgcgtctc tgggtaacaa
   114601 gtgttgactc aagcaatgac gtgcgtatct ctatggatat tttgagccaa gtgtctgaaa
   114661 cttaccgtaa gattcgtaac actcttcgtt tcttgattgc caatacatct gactttaacc
   114721 cagctcaaga tgtagtcgct tacgataaac ttcgttcagt tgataagtac atgactattc
   114781 gctttaacca gcttgtcaag accattcgtg atgcctatgc ggactttgaa ttcttgacga
   114841 tctacaaggc cttggtgaac tttatcaacg ttgacttgtc agccttctac cttgattttg
   114901 ccaaagatgt tgtttacatt gaaggtgcca aatcactgga acgccgtcaa atgcagactg
   114961 tcttctatga cattcttgtc aaaatcacca aactcttgac accaatcctt cctcacactg
   115021 cggaagaaat ctggtcatat cttgagtttg aaacagaaga cttcgtccaa ttgtcagaat
   115081 taccagaagt tcaaactttt gctaaccaag aagaaatctt ggatacatgg gcagccttca
   115141 tggactttcg tggacaagca caaaaagcct tggaagaagc tcgtaatgca aaagttatcg
   115201 gtaaatcact tgaagcacac ttgacagttt atccaaatga agttgtgaaa actctactcg
   115261 aagcagtaaa cagcaatgta gcacaacttt tgatcgtgtc tgagttgacc atcgcagaag
   115321 gaccagctcc agaagctgcc cttagcttcg aagatgtagc cttcacagtt gaacgtgctg
   115381 ctggtgaagt atgtgaccgt tgccgtcgta ttgacccaac aacagcagaa cgcagctacc
   115441 aggtagttat ctgtgaccac tgtgcaagca tcgtagaaga aaactttgtg gaagcagtcg
   115501 cagaaggatt tgaagagaaa taagattgaa aagtctaggc aaaattcaat ttgagaagaa
   115561 aagacaacta attttatagt ctattaaacg cattgtatca cgtttttgaa cacctgatac
   115621 gatgcgtttt ttatttattt taaaaatttg cgaggtatga ctttttatac tcaacaagaa
   115681 tcaaagagaa acttagcaag ctaacagtag taagataaaa taggaatttg atattaggga
   115741 taagattgct aaatagtgta atattttta
//
LOCUS       DBERXF010000002        80645 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.02, whole genome shotgun sequence.
ACCESSION   DBERXF010000002 DBERXF010000000
VERSION     DBERXF010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 80645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80645
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.02"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(166..1914)
                     /locus_tag="ACL8JK_000112"
     CDS             complement(166..1914)
                     /locus_tag="ACL8JK_000112"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785076.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGRVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKRAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQFPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(1916..3640)
                     /locus_tag="ACL8JK_000113"
     CDS             complement(1916..3640)
                     /locus_tag="ACL8JK_000113"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785077.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLSKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            complement(3698..4636)
                     /gene="msrB"
                     /locus_tag="ACL8JK_000114"
     CDS             complement(3698..4636)
                     /gene="msrB"
                     /locus_tag="ACL8JK_000114"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGS1785078.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4703..4855)
                     /locus_tag="ACL8JK_000115"
     CDS             complement(4703..4855)
                     /locus_tag="ACL8JK_000115"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785079.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTDDVSSRHCFEVVDRTDEVS
                     NIYTVR"
     gene            complement(4931..5800)
                     /gene="thrB"
                     /locus_tag="ACL8JK_000116"
     CDS             complement(4931..5800)
                     /gene="thrB"
                     /locus_tag="ACL8JK_000116"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HGS1785080.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(5802..7088)
                     /locus_tag="ACL8JK_000117"
     CDS             complement(5802..7088)
                     /locus_tag="ACL8JK_000117"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HGS1785081.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7239..7976)
                     /gene="mecA"
                     /locus_tag="ACL8JK_000118"
     CDS             complement(7239..7976)
                     /gene="mecA"
                     /locus_tag="ACL8JK_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGS1785082.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8176..9210)
                     /locus_tag="ACL8JK_000119"
     CDS             complement(8176..9210)
                     /locus_tag="ACL8JK_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGS1785083.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9239..10672)
                     /locus_tag="ACL8JK_000120"
     CDS             complement(9239..10672)
                     /locus_tag="ACL8JK_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HGS1785084.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMI
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(10688..11674)
                     /locus_tag="ACL8JK_000121"
     CDS             complement(10688..11674)
                     /locus_tag="ACL8JK_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1785085.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11676..12779)
                     /locus_tag="ACL8JK_000122"
     CDS             complement(11676..12779)
                     /locus_tag="ACL8JK_000122"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS1785086.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12769..13614)
                     /locus_tag="ACL8JK_000123"
     CDS             complement(12769..13614)
                     /locus_tag="ACL8JK_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS1785087.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDILPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(13893..15167)
                     /gene="psr"
                     /locus_tag="ACL8JK_000124"
     CDS             complement(13893..15167)
                     /gene="psr"
                     /locus_tag="ACL8JK_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HGS1785088.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15164..16012)
                     /gene="pheA"
                     /locus_tag="ACL8JK_000125"
     CDS             complement(15164..16012)
                     /gene="pheA"
                     /locus_tag="ACL8JK_000125"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGS1785089.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(16009..16485)
                     /locus_tag="ACL8JK_000126"
     CDS             complement(16009..16485)
                     /locus_tag="ACL8JK_000126"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGS1785090.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRHVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16478..17761)
                     /gene="aroA"
                     /locus_tag="ACL8JK_000127"
     CDS             complement(16478..17761)
                     /gene="aroA"
                     /locus_tag="ACL8JK_000127"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGS1785091.1"
                     /translation="MKLKTNISHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVVTIQGVGMDGLKAPQNALDMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTIPLKKMGVSISGQTERDLPPLHLKGTKKLAPIQY
                     ELPIASAQVKSALMFAALQAQGESVIIEKECTRNHTEDMLQQFGAHLSVDGKKITVRG
                     LQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17853..18191)
                     /locus_tag="ACL8JK_000128"
     CDS             complement(17853..18191)
                     /locus_tag="ACL8JK_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HGS1785092.1"
                     /translation="MSNIYDSANELSRGLRELPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18202..19305)
                     /locus_tag="ACL8JK_000129"
     CDS             complement(18202..19305)
                     /locus_tag="ACL8JK_000129"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGS1785093.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSEIILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQAMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVVK"
     gene            complement(19315..20481)
                     /gene="aroC"
                     /locus_tag="ACL8JK_000130"
     CDS             complement(19315..20481)
                     /gene="aroC"
                     /locus_tag="ACL8JK_000130"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGS1785094.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20491..21558)
                     /gene="aroB"
                     /locus_tag="ACL8JK_000131"
     CDS             complement(20491..21558)
                     /gene="aroB"
                     /locus_tag="ACL8JK_000131"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGS1785095.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(21577..22431)
                     /locus_tag="ACL8JK_000132"
     CDS             complement(21577..22431)
                     /locus_tag="ACL8JK_000132"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGS1785096.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(22421..23098)
                     /gene="aroD"
                     /locus_tag="ACL8JK_000133"
     CDS             complement(22421..23098)
                     /gene="aroD"
                     /locus_tag="ACL8JK_000133"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGS1785097.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23095..24258)
                     /locus_tag="ACL8JK_000134"
     CDS             complement(23095..24258)
                     /locus_tag="ACL8JK_000134"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGS1785098.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRSAYYQDDLTTTYRLFNQ
                     EGDGFGGLTVDLYGNYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(24942..26576)
                     /locus_tag="ACL8JK_000135"
     CDS             complement(24942..26576)
                     /locus_tag="ACL8JK_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785099.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLFMFINIAFRFPFEEMPSFFSTMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALAGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVTLVMVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEDKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(26557..27306)
                     /locus_tag="ACL8JK_000136"
     CDS             complement(26557..27306)
                     /locus_tag="ACL8JK_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785100.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETFSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            27485..28939
                     /locus_tag="ACL8JK_000137"
     CDS             27485..28939
                     /locus_tag="ACL8JK_000137"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HGS1785101.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEGLVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(29028..31646)
                     /gene="alaS"
                     /locus_tag="ACL8JK_000138"
     CDS             complement(29028..31646)
                     /gene="alaS"
                     /locus_tag="ACL8JK_000138"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGS1785102.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDCEGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVDNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAIAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(31668..32153)
                     /locus_tag="ACL8JK_000139"
     CDS             complement(31668..32153)
                     /locus_tag="ACL8JK_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGS1785103.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32428..32667)
                     /locus_tag="ACL8JK_000140"
     CDS             complement(32428..32667)
                     /locus_tag="ACL8JK_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785104.1"
                     /translation="MKMSTFFNKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(32920..33990)
                     /locus_tag="ACL8JK_000141"
     CDS             complement(32920..33990)
                     /locus_tag="ACL8JK_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1785105.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(33987..34760)
                     /locus_tag="ACL8JK_000142"
     CDS             complement(33987..34760)
                     /locus_tag="ACL8JK_000142"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1785106.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34757..35563)
                     /locus_tag="ACL8JK_000143"
     CDS             complement(34757..35563)
                     /locus_tag="ACL8JK_000143"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1785107.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWIMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDEMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35544..36701)
                     /locus_tag="ACL8JK_000144"
     CDS             complement(35544..36701)
                     /locus_tag="ACL8JK_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785108.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36861..37766)
                     /gene="murB"
                     /locus_tag="ACL8JK_000145"
     CDS             complement(36861..37766)
                     /gene="murB"
                     /locus_tag="ACL8JK_000145"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGS1785109.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(37878..38630)
                     /locus_tag="ACL8JK_000146"
     CDS             complement(37878..38630)
                     /locus_tag="ACL8JK_000146"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family glutamic-type intramembrane
                     protease"
                     /protein_id="HGS1785110.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDASIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(38640..39371)
                     /gene="budA"
                     /locus_tag="ACL8JK_000147"
     CDS             complement(38640..39371)
                     /gene="budA"
                     /locus_tag="ACL8JK_000147"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGS1785111.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            39513..40784
                     /locus_tag="ACL8JK_000148"
     CDS             39513..40784
                     /locus_tag="ACL8JK_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGS1785112.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCLLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(40804..41619)
                     /locus_tag="ACL8JK_000149"
     CDS             complement(40804..41619)
                     /locus_tag="ACL8JK_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1785113.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVDAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKVQLTSLTNMGEAVNELQTGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(41776..42429)
                     /gene="phoU"
                     /locus_tag="ACL8JK_000150"
     CDS             complement(41776..42429)
                     /gene="phoU"
                     /locus_tag="ACL8JK_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGS1785114.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(42441..43199)
                     /gene="pstB"
                     /locus_tag="ACL8JK_000151"
     CDS             complement(42441..43199)
                     /gene="pstB"
                     /locus_tag="ACL8JK_000151"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS1785115.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(43212..44015)
                     /gene="pstB"
                     /locus_tag="ACL8JK_000152"
     CDS             complement(43212..44015)
                     /gene="pstB"
                     /locus_tag="ACL8JK_000152"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS1785116.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(44026..44910)
                     /gene="pstA"
                     /locus_tag="ACL8JK_000153"
     CDS             complement(44026..44910)
                     /gene="pstA"
                     /locus_tag="ACL8JK_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGS1785117.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(44900..45817)
                     /gene="pstC"
                     /locus_tag="ACL8JK_000154"
     CDS             complement(44900..45817)
                     /gene="pstC"
                     /locus_tag="ACL8JK_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGS1785118.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(45817..46695)
                     /gene="pstS"
                     /locus_tag="ACL8JK_000155"
     CDS             complement(45817..46695)
                     /gene="pstS"
                     /locus_tag="ACL8JK_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGS1785119.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(47269..48573)
                     /locus_tag="ACL8JK_000156"
     CDS             complement(47269..48573)
                     /locus_tag="ACL8JK_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGS1785120.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(48574..49347)
                     /locus_tag="ACL8JK_000157"
     CDS             complement(48574..49347)
                     /locus_tag="ACL8JK_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGS1785121.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRSVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(49337..49615)
                     /locus_tag="ACL8JK_000158"
     CDS             complement(49337..49615)
                     /locus_tag="ACL8JK_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGS1785122.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(49615..50016)
                     /locus_tag="ACL8JK_000159"
     CDS             complement(49615..50016)
                     /locus_tag="ACL8JK_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGS1785123.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(50226..50843)
                     /locus_tag="ACL8JK_000160"
     CDS             complement(50226..50843)
                     /locus_tag="ACL8JK_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGS1785124.1"
                     /translation="MKTKLIFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLCLKSRRK"
     gene            complement(50833..51606)
                     /locus_tag="ACL8JK_000161"
     CDS             complement(50833..51606)
                     /locus_tag="ACL8JK_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGS1785125.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(51617..52354)
                     /locus_tag="ACL8JK_000162"
     CDS             complement(51617..52354)
                     /locus_tag="ACL8JK_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGS1785126.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEEYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAEQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(52359..53489)
                     /gene="hemW"
                     /locus_tag="ACL8JK_000163"
     CDS             complement(52359..53489)
                     /gene="hemW"
                     /locus_tag="ACL8JK_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGS1785127.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(53573..53962)
                     /locus_tag="ACL8JK_000164"
     CDS             complement(53573..53962)
                     /locus_tag="ACL8JK_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGS1785128.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(53935..54361)
                     /locus_tag="ACL8JK_000165"
                     /pseudo
     CDS             complement(53935..54361)
                     /locus_tag="ACL8JK_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
     gene            complement(54362..55150)
                     /gene="lgt"
                     /locus_tag="ACL8JK_000166"
     CDS             complement(54362..55150)
                     /gene="lgt"
                     /locus_tag="ACL8JK_000166"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGS1785129.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGFRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(55143..56078)
                     /gene="hprK"
                     /locus_tag="ACL8JK_000167"
     CDS             complement(55143..56078)
                     /gene="hprK"
                     /locus_tag="ACL8JK_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGS1785130.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(56208..56384)
                     /gene="rpsU"
                     /locus_tag="ACL8JK_000168"
     CDS             complement(56208..56384)
                     /gene="rpsU"
                     /locus_tag="ACL8JK_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGS1785131.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(56464..56973)
                     /locus_tag="ACL8JK_000169"
     CDS             complement(56464..56973)
                     /locus_tag="ACL8JK_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785132.1"
                     /translation="MNKEEFLKIKEAYKSARTEERKSIIGFITKKKDKEGNFLFTKSK
                     DKPYTTRNQYSGGGGNKKYTSGSRLSRPYDLSNHMWIDLSYKGNDILISLQSFDIDPN
                     SKELHVLYDRIGILFEQSKKIPIFKDCYTITKVSDAFLKMETTNWELPLSEADMEEMV
                     NYIINHYEE"
     gene            complement(57051..57758)
                     /locus_tag="ACL8JK_000170"
     CDS             complement(57051..57758)
                     /locus_tag="ACL8JK_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGS1785133.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHVVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            57909..58937
                     /gene="queA"
                     /locus_tag="ACL8JK_000171"
     CDS             57909..58937
                     /gene="queA"
                     /locus_tag="ACL8JK_000171"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGS1785134.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(59598..59987)
                     /locus_tag="ACL8JK_000172"
     CDS             complement(59598..59987)
                     /locus_tag="ACL8JK_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGS1785135.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(60041..60748)
                     /locus_tag="ACL8JK_000173"
     CDS             complement(60041..60748)
                     /locus_tag="ACL8JK_000173"
                     /inference="COORDINATES: protein motif:HMM:NF019142.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGS1785136.1"
                     /translation="MFRRNLNTSFAHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVK
                     VATKPKVVTKKISSTRIRFEKDETKDRSENHVTIDGEDGYVTTTRTYDVNPETGHVTE
                     KVTVDRKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTT
                     ITYDVDGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEISIETEYLDGPTLDKSQE
                     VEEVGEIGKLLLLQSIL"
     gene            complement(61447..61998)
                     /locus_tag="ACL8JK_000174"
     CDS             complement(61447..61998)
                     /locus_tag="ACL8JK_000174"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1785137.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKVYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(62296..63120)
                     /gene="nadE"
                     /locus_tag="ACL8JK_000175"
     CDS             complement(62296..63120)
                     /gene="nadE"
                     /locus_tag="ACL8JK_000175"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGS1785138.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKNFV
                     LGISGGQDSTLAGRLAQLAIEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(63117..64577)
                     /locus_tag="ACL8JK_000176"
     CDS             complement(63117..64577)
                     /locus_tag="ACL8JK_000176"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGS1785139.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLCNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(64693..65181)
                     /locus_tag="ACL8JK_000177"
     CDS             complement(64693..65181)
                     /locus_tag="ACL8JK_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6773 family protein"
                     /protein_id="HGS1785140.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(65171..65380)
                     /locus_tag="ACL8JK_000178"
     CDS             complement(65171..65380)
                     /locus_tag="ACL8JK_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1785141.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(65766..66494)
                     /locus_tag="ACL8JK_000179"
     CDS             complement(65766..66494)
                     /locus_tag="ACL8JK_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1785142.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     ETSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTIMMNTSNDLFIKAIELLPFYSLPLFVVSNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
     gene            complement(66510..67380)
                     /locus_tag="ACL8JK_000180"
                     /pseudo
     CDS             complement(66510..67380)
                     /locus_tag="ACL8JK_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(67736..68464)
                     /locus_tag="ACL8JK_000181"
                     /pseudo
     CDS             complement(67736..68464)
                     /locus_tag="ACL8JK_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
     gene            complement(68710..69021)
                     /locus_tag="ACL8JK_000182"
     CDS             complement(68710..69021)
                     /locus_tag="ACL8JK_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHY zinc finger protein"
                     /protein_id="HGS1785143.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(69036..70322)
                     /locus_tag="ACL8JK_000183"
     CDS             complement(69036..70322)
                     /locus_tag="ACL8JK_000183"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HGS1785144.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESFEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            70919..71488
                     /locus_tag="ACL8JK_000184"
                     /pseudo
     CDS             70919..71488
                     /locus_tag="ACL8JK_000184"
                     /inference="COORDINATES: protein motif:HMM:NF021048.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
     gene            71496..72686
                     /locus_tag="ACL8JK_000185"
     CDS             71496..72686
                     /locus_tag="ACL8JK_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGS1785145.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(73201..74193)
                     /locus_tag="ACL8JK_000186"
     CDS             complement(73201..74193)
                     /locus_tag="ACL8JK_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1785146.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            74353..76107
                     /locus_tag="ACL8JK_000187"
     CDS             74353..76107
                     /locus_tag="ACL8JK_000187"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785147.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNINNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            76091..77812
                     /locus_tag="ACL8JK_000188"
     CDS             76091..77812
                     /locus_tag="ACL8JK_000188"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785148.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            77823..78452
                     /locus_tag="ACL8JK_000189"
     CDS             77823..78452
                     /locus_tag="ACL8JK_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGS1785149.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            78353..78910
                     /locus_tag="ACL8JK_000190"
     CDS             78353..78910
                     /locus_tag="ACL8JK_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS1785150.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            78898..80262
                     /locus_tag="ACL8JK_000191"
     CDS             78898..80262
                     /locus_tag="ACL8JK_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785151.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKKLSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT        24800 a        17174 c        14736 g        23935 t
ORIGIN      
        1 ttatctacaa cctcaaagct gtgctttgag caacctacgg ctagcttcct agtttgctct
       61 ttgattttca ttgagtatta cagtgaacaa tttttctagc tattgtaaca aaaaagtcac
      121 tcgaaggcaa cttttttcgt ccataaactt tcaaaagaga atcgcttatt cagaactaaa
      181 agccgcagct ttttgcattt ggtaatactt accctttcta tccatgagtt cttgatggtt
      241 accatattca acaatatcac catctactaa gacaagaatt aaatccgcat cctgaatggt
      301 tgacaaacgg tgagcaatga tgaagcttgt gcggcccttc atgagttttg caaaggcatc
      361 ctgtaccagc acttctgtcc gtgtatcaat ggaagaagtt gcctcgtcta agataagaat
      421 ctttggaata gccagaaaga ctcgggctat ggtcaagagc tgagcttggc cgacagagag
      481 agattctcca gcattttcca acttggtatc gtatccctgt ggaaactgtt ggatgaaaaa
      541 gtctgcatta gctgctttgg cagcagcaat tacttgctct cgactggctt caggattgcc
      601 aaaggcaata ttatcatgaa tggtcccttg tgtgagccag gtttcttgaa gcaccatacc
      661 aaactgctgt ctcaatgata ctcgtgtata atcataaatg gattgcccat ccagcaagat
      721 atctcccgag ctaatgggat aaaaacgcat aaggagattg ataagagttg attttccagc
      781 acctgtcgga ccaacgatgg ctaccttact accagctgga atatcgatag acaagtcctt
      841 aatcaaaatt ttttcaggat ggtagccaaa agagacatgt ttaaaggaaa tagctctctt
      901 aacttggtca ctggtcaaga cttccttacc tgtttcagcc acttcagggc tatctaagac
      961 tccatagata cgctctacgc aagccagagc actttgcaac tcagctagca ctgaagaaat
     1021 atcgttaaag ggcttggtgt attgctgaac atagttcaaa aaagtcacta aacgaccgac
     1081 ggtcaaggtt gaacccatca tgatacgata agctcctact ccagctaaaa gggcataaat
     1141 gagtgcattt acaaagcgag tcgaaggatt gaccgttgaa gaataaaaga tggctgactg
     1201 agaatagcct gagtagttgt catgagcctc acgcaatctt tggataaact ctgtttgagc
     1261 attgaaggac tggattatag tctgctggct aagcgattct tcaatcaact gggtctgaat
     1321 ccccctcgtc tctgtttgct tctggaagag atgataggat ctcttggcaa taaagcgtga
     1381 aatcaccatg gacagtggcg tcaacagcaa gactaagaga gtcatgagga gatgaatttg
     1441 gagcatggct agaatactaa ccaaaatcat caaaacacca atgaaaaatt ggttaaaaat
     1501 catggtcaag ccagctgcca actgttcgat gtctgtggtt acacgactaa ccatctctcc
     1561 actaccttgc ctatctacaa aggcaatcgg taaccgatgg agtttatgga tgattcgctc
     1621 ccgtaaatct ctggtataag agaagattag acgattatag aggagaggat tggcccattg
     1681 tactagagta tttcctatta ccaccaagag catctggaga aaaatctgcc aaaaaactgg
     1741 tgatgaacca gccactagga cttggtcaat gacccgccca atcagaatag gtaggtaaat
     1801 tgataagcca acttgggcaa tagttcctag aaaggctagg aaaaggagga aaggatggct
     1861 tgctaaatct acggctaaac gtttgagcgt ctggtttaca gtttgtcgtt tcattctagt
     1921 cctcctttcc atgttgggat gcattgattt cacaatagac ttggctggat ttcatcaagt
     1981 catcgtgctt gccaacagct agcaactcac ctttttccaa gaggagaatc tggtccgcca
     2041 tctgtaaagt tgaggttcgt tgagagatca aaattaagct cgtgtttgga aaattttctc
     2101 taatagcttt caagagcttg gactctgtaa tggtatccag tgccgaggtt gcatcatcta
     2161 ggatgagaaa cggagcttgg cgcaagactg ctcgggcgat agacaatctt tgtttttgtc
     2221 cacctgagaa atttcgcccc cctgcctcaa ctagagcatc caagagtcct tccttttcac
     2281 tgacaaaatc cttagcttgc gcaatctcca aggcctgcca gagttcctgg tcagatactt
     2341 cttgattgaa acctagagtc aagttggaac gaatggttcc tttaaagagt tcgacctttt
     2401 gaggtacata ggcaatccaa gaccgccact gctccaaatt aagaggacta cgtccatttt
     2461 gataaaggtc aatgttcccc ttgtctactg gataaagtcc aagtaagagt tgcaccaagc
     2521 ttgatttacc agaaccagtc cccccaatga taccaaggat ttgtccttga gtcatatcaa
     2581 aggaaatgtc tctcagagaa ggctgggccg catcaggata ggtaaaagtc aattcttgga
     2641 cttgtaaaac ccgaccactg gtaacttgct tttgttctaa ttctgaatgg atgttttcgg
     2701 gagattccgc aaagacctcc tcgattctct tggctgagat ataggactgg ttgagggaat
     2761 tgatcagcat ggcaagcttg accaattcca ccaaaatctg taagaggtaa ttgataagag
     2821 caatgagagc accttgactg agcactcctc cttgaattga aatatagcct tgccagataa
     2881 taacgagaag agttccattg acaatcagat aggtcagagg tgttaataaa ctagaccaga
     2941 aacctgtctt ttcttgtaat ctagcataaa cttggttaag ggtttgaaaa atctgtaact
     3001 ctcgtttttc ttgaccaaaa gcacgaataa cccgcatccc ttgcaattgc tggcgcgttt
     3061 cctgaaccag ttggtccgtt ttctttctga gactactgta gagaggattg accaatcgag
     3121 ataaccctac aatgacaatg gtcaaaatgg caaccatgac taagaaccag aaagtcaact
     3181 cagctgagat tcgataagcc ataaaaatgg caccaaaaac gataatgggc gctcgcaaaa
     3241 agagacgcag gaattgattg ataccagtct gaatctggta ggtatccgaa gtcaagcgag
     3301 tgaccaaact agaagttgtc agacggtctc tgctgtcctt ggacaaggaa agaatatgac
     3361 gataaagatc gtttgtcaat tccttagcaa agcctactgc tgcctttgct gagtaaaatt
     3421 gagctatcaa ggccactaaa acgccaatta ctgcaaagat aaggagcagg ccaatctgca
     3481 tccagagatg accttgatct ccctgaggta aagattggtc aacaatccca gcaatcacca
     3541 tgggaaccaa gagctcaaaa acagcttcta acagcttgaa caagggggct aaaattgatt
     3601 ccttgatgta gggtttgaag taagataata ggtgtttcat aaatcccttc tattcatatt
     3661 ctagaaatga agaaagtggg aagccccact ctctgtttta tttgtttaag taaggcaata
     3721 gatagccata tcctgctttt tccatctcat ccttggccac aaagcgtaaa gaagcagaat
     3781 tgatacagta acggaggccg cctaactccc gcggtccatc tgtgaaaaca tgacccaagt
     3841 gagcactgcc tgaacgagaa cgaacttcaa ttcgctccat tccatggctc agatccttgt
     3901 aataatgaat caactctttg gaaatcggac ggctaaaact tggccaacca caacctgaag
     3961 caaacttatc cttggcaaaa aagagtggct cacctgtcgt aatatctaca taaatcccct
     4021 cttcaaaggt ttggtcatag gcattggtaa atggagcctc tgtagcagct tcttgtgtga
     4081 cacgataaga ctcttcagat agactggcct tcaacacctc ttgactaggc ttttcatagt
     4141 ttgctgcatc aatcaatggc ttatcagcat cggtcacatc gatatgacag taacctgaag
     4201 gattcttcct gagataatct tggtggtagt cttcagccag gatgtagtgg cgtaattgct
     4261 ccacttctac tgcaatcttt cgacccagca tgcgttcctg ctcctgtacc actgtgtaga
     4321 tagctggcaa atctgcttca tcctgataat aaatcccagt tcgatattgg cgaccacggt
     4381 cattcccttg ttgattgata gatagaggat cgataactcg gaaataataa agtaaaatct
     4441 ctctgagtga cacttccttc tcatcgtaaa tcacttggac cgtttctgca tggtctgttt
     4501 ccttgatcaa ctggtaattg gtcgtttcga cttgaccatt agcgtagcca acactggttt
     4561 ctagcactcc agaaatgcgt gaaaaatatt cctctaggcc ccaaaaacaa ccacctgcta
     4621 gataaatttc tgccatcttt atttctcctt tatcacgttt ttaactaata ctcttcgaaa
     4681 atctcttcaa accacgtcag cgtcacctta ccgtatatat gttactgact tcgtcagttc
     4741 tatccacaac ctcaaaacag tgtcttgagc tgacgtcgtc agttctatcc acaacctcaa
     4801 aacactgttt tgagcagcct gcggctagct tcctagtttg ctctttgatt ttcattgagt
     4861 ataaacttct tttcacaaaa aggatatgaa accctctggt caagagtttc cccatcctat
     4921 cttctattct ttattttgct tctacacgga caccttgggt atcaactctc aagtcatgca
     4981 gttttccttt gaaaggttgc ttttccaatt ctgccttaat tgttggcatc ttgtcatgag
     5041 aagccagaac cataactgtc ggcccagcac cagaaaggta ggttgcatag gccccatttt
     5101 ctttggtcac ttgcttaatc atcgcaaatt ctcttaccaa gtcctgacga tagcgctcat
     5161 ggaagaggtc tccctcgatt gcttgcccag cggtcaccat gtctcctgcc aacaaggcag
     5221 caaccgctac attggcgata gaacttgcag caacagcttc cttataagat aattttttag
     5281 gcaagacact acggctgtcg cgagtacgta attcatagtt tggaatgtaa gctagaaaat
     5341 cacactctgg aaagtctgct acgatagcag agacttgccc ttcaacagaa cttgcaataa
     5401 cgagattacc ataaatggct ggagccacat tgtcaggatg cccttcaatc ttggtcgcta
     5461 actgcaattt ttcatggtct gataagttga gttgacccag ttggttggct agttcaatcc
     5521 cagcaacgat aaccgagctg gaagaaccca aaccgcgcgc caaagggaca tcactggtca
     5581 ttttcaagcg tcttggttgc aagtctggta caatttgcaa agcgattttg agcaagagat
     5641 tacgctcatc atgtggaatc catttgccaa tctggtgttc aatcagccac tcatctcgtt
     5701 cttcgcagac ctcaatttga agatacttgg ttacagctac accgaccgag tcaaaacctg
     5761 gcccgatatt ggcactggtt gcaggtacaa taatcttcat cttattctcc tagcaccttg
     5821 aaggtattca aaaggtcgaa ttctgaaacc ttcttcaatt cagctgagac attttcaagc
     5881 tgggctttat taatcttgtg tgtgatgata acgacacgcg ccttgtcacc ctctttgcca
     5941 tcttgaagga tttgcttaaa ggaaatatct tgagcattga agatttcagc caacttcaag
     6001 acctgacctt ttgagtctag agccaagatt gagaaatagt agtttgcttt gacatcttca
     6061 ggatttgcca agaccaagtc acggctatat tcgttgaagt ctttgccaat agtaccatca
     6121 ttcaaacgac gaacgatacg gacaatatca gctacaacac ttgttgcagt tggtttttga
     6181 ccagcacctg gtccgtagta catagactca ccaataccga tagattctac aaagacagcg
     6241 ttcattacgc cattcacact agcaagtggg tgcgctttag gtaggaaggt tggagtcact
     6301 tctgcagcaa tacctgaaga agtttcctca atagaaccaa ccaatttcac tacgtaacca
     6361 agctcttgag ctacagctac gtcttctggt gtgatattgc ggattccctt gtgggctaca
     6421 tcatcaaagg caatcttcat gccaaaggca aattggctca aaataaccat cttgtaggct
     6481 gcatcaatcc catctacgtc attcgtcgga tcgctttctg caaatcctag acgttgtgct
     6541 tccgcaagag catcatcgta agaccagcct tcttccacca tcttggtcac catgaagttg
     6601 gaagttccgt tgactactcc aagcacgcgc gtaattttat cagaagccaa ggaatttgct
     6661 aaagtacgaa gaattggaat cccaccagca actgctgctt cgtagtaaag tgctaccttg
     6721 ttagcttgag cgatttctag caattctgcg ccatggacag ctaaaaggtc cttgttagca
     6781 gtaacaacgt gttttccagc ttccaaggca cgagtgataa aggttttagc aggctcaata
     6841 cgccccatca attccactac gatagtaata tcctggtctg ataaaatatc atccacattg
     6901 gttacaaagt taaagtcatt ccctgctgca agcaagcgat ttttttcatc ttcatccttg
     6961 accaatacct tagcaacttt gatatctgaa tgtgctgatt gattgatttt tcctccattt
     7021 tcctttagga ggaaaggcac accacttgca acggtaccaa atcctagtaa agcaatttta
     7081 actgtcatct ttatctcctc gaaattttct aatatagcca ttataacaga attttgtgaa
     7141 aattcctatt atagtaaatc actatttcag tataaaaaga aaaaacgaat cagacgattc
     7201 gctcttctta aaatctgaaa atagctttcc agaaaggatt agccgatttt ttgcagattg
     7261 agcactgcat cgtgactcat caagacttga ccatactctt gtaagactga gcgactgata
     7321 tcactatcgt ctgcaaactc gcgcatacgg gccaacagcc aagctggata tgggcttgga
     7381 tgattttcaa tatccactaa aatggtcaaa taatagcgct cgttcatttt gtagagttca
     7441 gaagtttcca tttcaaaagt cactgtcttg gcaaaagcta ccaagtcagc caacttagca
     7501 aaagaaagga tgtagtagat gtaaggttct ttcttactct cagcttcttg ttcagcttgc
     7561 tcttgctctt cttccttggc ttcaacttgc tcaagagatt gaatggcttc gatatcatcc
     7621 ttggttttgt ctgcgatgct tttttccagg gttttgataa attcatctgg agacatttga
     7681 gccaattctt ccatatctgg caaatccgat aagtcttcaa aatctagatt ttggtcaatc
     7741 tttgacttgg tcacaaagac atctacctta tcaggttttg gagtcacacg gaagctcaac
     7801 atgcctgtat ccagaaagct atcaggcatc tctagctcat ccaagatagc ataaaagaac
     7861 tcttctgttt tttcttgagg aacgagaaag tcagcaatct ccattccacg atccatcaaa
     7921 tcctctaaag acatcgtgat ttttaaagtt gtatcactaa tttgtttcat tttcattgct
     7981 agtaacctca tactttcagt tctatctatt atactagatt tttacgattt tatcaaaaga
     8041 aggctcctct atacggatag attttcccta gggtctttct ataggagact ccaaaagaaa
     8101 atttctgcag acagatagaa aaagccttca aaatcggcta agagccgatt ttgaagacct
     8161 tatacatcag aatacttata atttaaaggt tgctacaccg aggatagaac gatttaagtt
     8221 tctgagaatt tgaagacttt gctcaaattt cttataacga gtcactccgt actcttcaac
     8281 aagaaggact gtatctcttt ccaaaagaga tgatacatcc tgtaaatcta caaaatgcat
     8341 tccttttaaa gcttcttgac tctgtttcaa tttatctaag atagctttat ttgagctaac
     8401 gatggtcaat tcctgtccag tatttttgta tgacaaaaca tctgctaggt tagcaattgt
     8461 tgtaatctct gttacaaaat caatttgata ctgagaaaaa tcacctactc tattgattgt
     8521 tggattaaag agataaacta acacatttcc catcacaacc aaaatcacac aaaccactcc
     8581 aataacaact aaacgaagaa tcagattttt cacatttaag ccaagcgctg tttcaccatt
     8641 tgcgttcaat tctttagagt tgatggtttc cagtttttca attttcacat ttgcataggc
     8701 atgtttaaat ttctcaatca acccatcaat ttttttctct aacaagtcat tggcatcttt
     8761 acttgatgtc aaaattttca caccaacccc tgcatcgtca atcatatagt agacggtcaa
     8821 ttttttccac caatagtcat tcgttgaatt tttcaaggtt gtttctgtcg tgtctaattc
     8881 actggcaatt tttttcaact cactgggttc tacatcattg aaaagataag ctccattcaa
     8941 attaccatca atcaatttcc cataaaaatc actataacca ccaatttgat gattcaaaat
     9001 cgttttggcc gactcttttg gaggagtgat tttatagata agataagttg aataacttgt
     9061 tgtatctttg acagtgtttt tattcctaac tgctttaatt gtaaatggta cagcaatgag
     9121 agcaaataaa gcgatgagag ctaaaatatt tgcttttcgc tttttataaa gatttgcaaa
     9181 caaatcagct actgaataat gttcaaacat gatttttttc tcctttgttt agtagatact
     9241 agttttcctt tgtaagcatt tttgctacaa atataatcac aagaacaatt ccccagaatt
     9301 gcattgtaaa taaattgaag aaactttctg aaaagctgct tcttggcata aagaatagat
     9361 tattcaagat gagtagggat aaagcaaata ggattgtcct tgagcgatag gctacttgca
     9421 gcatggctat aaataatacg ccgagtaaga aactaagcag aaagactcca atcataccat
     9481 agtcggtata caactccatg atataactac ttccgatacc atgccctttc aagtattcct
     9541 tgttcaagac aagataggat agattgtggg cataactatt actatcaata gctagttcca
     9601 cactattggt tgtatgttca aaggcttttc ctccgaaaat ggctcccaaa ctcccccttg
     9661 caaaataatc aagaacagga ccaaaagtaa aattacggaa atctcggtaa gggaggctac
     9721 tgttaaatag aaaacctcga gccagaacac caaaactagt cccttgttta tagataaagt
     9781 caagtaagat atcccagaaa cctgtatggg aaacttggac attatcccgt acataattga
     9841 gtactcccat cgctaacatg agaataggag aacctacaaa aatcgctaac ttttctttaa
     9901 acccaatcca ttttcctttt tcagtttgct cccgcataaa gtaataaaca aaagcaaata
     9961 aaatacttaa aataaaggga tttcgtgtcc caattgccaa atgaatagta ttagctgcaa
    10021 taaaggagac aagcactgct gtggcctgca atttctttgg cttggttgcc agatacatac
    10081 acattgcata gaccgtaaag gtagacaaaa tgtaggtaaa ataaggcagt ttactttcaa
    10141 aatttgcata gtaggcatag taggaagtct gcaaacgata caagagccgt tcaaataacc
    10201 gaatgaaata gaaaggataa gttagaagaa aaactcctag tgatacaaag cgtaaccgct
    10261 tgatataaac ctcttttaga gaatttccta tatttgctac ttttattttc ttcctagcta
    10321 tgaagtaacg agccagaatg cctcctgtgg tcaagcccag aatcgaaatc atgacaacta
    10381 taaaggcaaa acgataggct attggatgat aggtatccaa agcaccatcc ctaaaataat
    10441 caatggtcgg tcttgatacc agaaatacaa aaatggttaa atagaaaata aaatggatta
    10501 agtaatactt gatatcattc caacaagcaa ttaagctact aaccaacaag aacaataaag
    10561 tagaaagtaa gctaacatta ttattattaa acagatacac aattccactt actagcgtca
    10621 aggcataact gactatggtc aaactaaata ataatcgttt cccatcaatc acttggtcac
    10681 ccccgttcta atgtaatttt ttagattttt caatattttt cagtaataag aatcgatata
    10741 aggaaatatt tatgaatagg gccaaagcac taattcttct ccccttacgg aaaattggat
    10801 tcctagaaat agcaaaggca tggcctttta aaaaacgatg aatctgagaa taggcttcaa
    10861 actgtttata ctgatcatct agcaacatct tatccagaat aaagaagtgg gcataggcca
    10921 atctgaaaaa agcgacctct ttcaagtcag gatagttttt cacaacttca ttataaaact
    10981 tttggtagat atcaatatag gctaaatcct tctctgcata gggtttggtc gtaatactat
    11041 cccctctatg gaaatagtaa taatagggtt tagtattaac cacatacttc ttggccaact
    11101 tgattaaatc aaaatggtaa taggcatctt cgtaaatcaa ccccttagga aaggataggg
    11161 cagttgcaat ctgtctcttg attagcttat tgcaaatcgt cccaggtatt ttttcaccta
    11221 tgaggtattc ctttagaaat gtttgagaat cacagacaaa atagtcatcc tgattggctg
    11281 actgtgggct ttcatcatta gcatagacat tcatgacacc acagctcgaa acatccgcat
    11341 cttcttgaac taattgctca tataagctct gaatcatttc tggatggata taatcatctg
    11401 agtcaataaa aatcagataa tccccgtgag cctgcttcat cccatcattt cgtgcttgcg
    11461 acaatccttc gttcttttta tgaagcactg acaccctgtc atcttgttca gcgattgaat
    11521 cacacaagcg accactttca tctgttgcac catcatcaac aagaataatt tccagatttt
    11581 gataggtctg cttctgaatg gaagctatcg atttttctag gtactgcgcc acattataga
    11641 ctggcacaat cacactaatt aatgcagttt ccatgctact cctctaatag tttttctact
    11701 tgttcgattt gttttgtaat tgtaaattgt tgaatgaatt ggctagcctc atcgacatca
    11761 aagtttgagg cagaagtcat gtaattagta atcgcctgag ctgcctcttg attgctctca
    11821 atgatttgtc caaatcgtcc ttcttgggat aattcctcag cccctccaac gtccgtagag
    11881 ataaaaggga gtcccagact caaggcctcc acatacactc caggaaaacc ttcttgttta
    11941 gacatagaca aaagaacttt cgtctgagat agatactgat aaggattttt ttgataacca
    12001 aggaaatgta catagtcctc aatcccatac tctttgactc gttttttcag ttcctcttcc
    12061 atatcaccag ccccgataaa atagagatga tagttttttc cctcttggtg taataatcgt
    12121 atcacttcca ctacacggtc agaaccctta ttttcctcaa tccgtccgat agtacagata
    12181 ctttgaggag caatctcgat atcgatcttc tcttgagatt tttctagaat agtctgaaaa
    12241 tcatatccat tgtagattgt ctgtaattta gaagtataat ctggataaac ttccttgata
    12301 gaattgctgg tcttttttga aatccctaca attgtattcg cagcatccaa ctggcttcta
    12361 tgtgattctc ttttagagct atccttaaga agttcttcaa tacttccatg aatccaagat
    12421 atcttcttga cttctcttct tttagagaac aacagtggtg gattcataat ggtaaaagaa
    12481 acttcaacat cataatcatc ttttacaagc aaacgacgag tcagtcttgg aaaataaatt
    12541 ctcattctcc acaaaaaagc tcgtaaccat ctggtttggc gataatcttg aagggatttt
    12601 aaaatgcgta catgctttgg aacagattca tatcccttgt caaagtgctc catttcaaga
    12661 atatcaatat catacttttc tggatccaga tttgaaacaa tggttgatag aatcttctct
    12721 gcaccacctc caagagaaaa agaccacata aaaaataaga tttttttctt agccaccata
    12781 ttctcccttg tattctgtat aagacttatc catatcagcg atgacagcat catgatgcgg
    12841 tacctgcttg tctgctggtg gaggcgtcat ataatcccca aaagcagttc tgagatagac
    12901 atcatagccg attggaatag gcatctctgt tccttcaaat ggcaagaaaa gattgtcttc
    12961 aaaagatgtg attgggtact tgtttctcat gtagccagga cctgagcata attctgtaat
    13021 gccatcacaa tcagccaaat catacttagt catttctttc tcagcttttt tccagatgcg
    13081 ataacggaga gattttggag tcaaacccag taaaatgcga cttccccatt tcatgagagc
    13141 accatgcttt tctggaatag tttgcgcaca aaagagtgaa taaatcaagg cccaacgaac
    13201 ctgttttttc cgctcagctg gatttttcgg ataataatcc aaaggcaaaa tatccaaggc
    13261 cagaccatgt ggcaaatcca aatcctgctg ataaggcttg atacaggtgg tttccttgtc
    13321 acgaatggta ataaaaagat tacgatcaac aaaatccttg tgactctttg acaagaaata
    13381 acgttcatct gcataacgag gccataattc tgctaatttc tcataatctt tacgaggcat
    13441 aaaaaagtct aggtcgtcgt cccaaggaat aaatcccttg tttcgaaggg caccaatagc
    13501 gcctccgcca cagagataac agagcaaatc atgttcttta caaaaggcca caaaatattc
    13561 agccatctcc agactacgag cctgaattgc ttttaaatca gtcatattgt tcattattct
    13621 ttctatcgta tcgtttcatt ataccacaaa caaggggtga aaatctattg cagactgtaa
    13681 aaaatcaaag cctgactgct atccaaatag ctatcaaact ttgatttttc tgtcttatac
    13741 tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtaggtata ggtaactgac
    13801 ttcgtcagtc ttatctacaa cctcaaaact gtgtttttag cagcctgcgg ctagcttcct
    13861 agtttgcact ttgattttca ttgagtatta tcttatctca agcccatttg agcgagcttg
    13921 gtttgatatt tgttttgatc aaccagcaag cccaagcctc cataaacatc ataggcatct
    13981 acccagtcac ccagttctgg aatcgtcaat ttttcaatac cattttttgc tccatccaaa
    14041 acagataaac cgtttgttag gaggaaagta tagggtacgt tggttgaggt catagcaaaa
    14101 acctttccaa gagcttcaga accagtgaaa agtttagtgg gatctttaat ttgctctaaa
    14161 attgctgtta aaacttgttg ctgtcttttt gtacggccgt aatccgcctc atcatcatca
    14221 cggaaacgag cataattgag cagggtcgag ccattcatct gctgttttcc gactttaatg
    14281 gtttgggttg gagactcagt ctcggtagca tataaatcat ctccgactgt agcttctgtt
    14341 aggggacgcc cattcaatgt tgaaaattga gcatcaatcg tcaccccatc agggaaaagc
    14401 gtgtcaatcg ctgtggcaaa ggcctggaaa tcaaccaagg cgtagtactt aatgtccaag
    14461 tcaaaattat ctttcaagac ttggcgaacc atttctgccc ctttttgccc ctcttgttct
    14521 cctaactcgt aggctacgtt taacttgtta tctgtctgtt ttctaccgtt aatcacttga
    14581 ctataaccat ctatatagac caaattatca cgcatgaaac tgactagctt cattttctta
    14641 tctgagcccc cgacatttaa taccataata gagtcagttc gtgtctcaac actgttctgg
    14701 ccgattcgac catcagtacc catgattaaa atattaactc catctctagt gtcctgacca
    14761 ttaaagactt ctacttgagc tgcccgggca tcagcagttt tctttgcgct agcatcttgg
    14821 taaccacgca aaaacatgaa taccatggcc aaagccacac agaccaaaag tgaaaaaatc
    14881 accataaaaa ttcgtttaag acggagcttc cgtcttttct tttttggagg gaaagagagt
    14941 gcttgtgatt tggattgtga gcgactccgg ttcgcatagc ttggtaagtc aacctgctct
    15001 tctctttctt gttccaagct agagctacta tttcccctag caagagttag cttttcttgc
    15061 aaataggcaa actcattttt ttctctctca ttgaggtagt gaatattttt tagcaaataa
    15121 tcataacgca actgctcatg atgacttaag ggattttctt tactcatctt ctctcctttc
    15181 catggtctga tattggataa ataggatagg cacccagaat tttatactgg attccaatcg
    15241 cttctaattc tttttgggca aagtggacca agtccttatc ggtataatcc acatcgataa
    15301 tgaaaaagta ttcacccagt gctgtcttga gtggacgact ttcaattttt gtcaagtcaa
    15361 ttcctcgcca agcaaaggtc gacagggcct tataaagtgc acctggaagg ttgtcaggta
    15421 atgtcaaggc caaactcatc ttttcagttt gtgcttgcaa gggaatacta ggcttttcag
    15481 ctcctagaac ccagaaacgt gtgaaattgg cttccatttc ctgaatatcc tcggcaatca
    15541 gttccaatcc atattcttca gcagaacttc taggtgcaac tgctgcaaag ggctggtctg
    15601 gatgttcgga aataaaacgg gccgcataag ctgtactagc tgttacctcg atttgagcct
    15661 ctggatattg ttcatcgatg aatttctttc cttgagccaa ggcctgtgga tgtgaaaaaa
    15721 tcttttcaat cttagtatgg cctggaacca ccatcaactg ctgatgaata ggctgaacga
    15781 tttctgctac tgcttggatg tgagcctgat gaaaaagata gtccaaggtt tcatgaacac
    15841 taccctcaat agaattttca actggcacca cagaatagtt cactaatcct tgctcataag
    15901 ctttgatgac atctgtaatg ttggcaaaag cctgcaattc ctcatgagga aaagctgtct
    15961 gcacaacgtg gtgtgaaaat gatcccttgg gacctagata agctattttc atcttagttc
    16021 ctctataatt tcctctgggc ttagcttggt cacatccaaa acccgactag ccacttcctc
    16081 ataccaagcc tgtctttctt gaaaaatagc tactagttct tccttgctat tatttagaaa
    16141 aagcggtcgc tgattgtcct tatcagctgc gatacgtagg tagagggttt caaaatctgc
    16201 tttcaggtag atgttatctg tattagtctt gagtaagtca cgatttctct gagaaataac
    16261 cactcctcct ccagttgaca cgacttggtc tgtttgtagt aaatcagcta ggacttctga
    16321 ttctacatga cgaaaggctg cttctccctt ttcagcgaaa aaattcgcaa tggacatacc
    16381 taggcgcttc tcaatcagag catccatatc aaggtaatta gggtccaagc ctcttgcaat
    16441 agtcgatttt ccagccccca taaaccctaa taacacctta gccatgaatc aagctctcca
    16501 aatcatcaaa gaaactagga tagctggtat tgatggcttc tgcacggtca agctccacct
    16561 ctccatctgc aaccaagagg gctgcgatag ctgtcatcat gccgatacgg tggtcaccaa
    16621 acgtattgac tctagcaccg tgaagagctg atttcccttt gataatcatc ccatctgccg
    16681 taggagtaat atctgctccc atactattta aggcgtctgc cacaacctga atacggtctg
    16741 tttccttgac cttgagctcc tcagcatcct tgataactgt tacaccttgg gcttgagtcg
    16801 caagcagggc aataatgggc aattcatcaa tcaaacgtgg aatcaaagcg ccaccaatct
    16861 ctgttccttt caagtcagaa gactcaacaa tcaaggtagc agatttagcg actggatcga
    16921 tttcagttat ttccaatttt ccacccatgg cacgaatgac atcaataata ccggtgcgag
    16981 tttcgttgat ccccacattc tgcagcacta gacgagaatt tggaacaatc aaacctgcga
    17041 ccaaccaaaa ggctgcactg gaaatatctc ctggaacaac caccttttgt cctgtcagtt
    17101 tttgaagtcc tcggactgtg attttcttgc catccacact taaatgagca ccaaattgtt
    17161 gcagcatatc ttcagtatga ttacgggtgc attctttttc gataatcact gactctccct
    17221 gagcctgcaa ggccgcaaac atcaaggctg acttgacttg ggcagaggca attggcaact
    17281 catactgaat aggtgctagt tttttcgtcc cttttaagtg aaggggaggc aagtctcgct
    17341 cagtttgccc tgaaatgcta acgcccattt ttttcagtgg aatcgtcaca cggtccatag
    17401 gacgtttgga aagactatcg tctccgaaca tttctacttc gaagtctgca ccagcaagga
    17461 cacctgaaat caggcgaatc gaggttccag aatttcccat atcaagggca ttttgtggag
    17521 cttttaggcc gtccataccg acaccttgaa tggtaacaac cccatcttta tcctcaatct
    17581 ctacaccaag atcacgaaag acctgcatgg ttgaaaggac gtcttcaccc cgcaaaatat
    17641 cataaacctt ggtctctccc tcagctaaac ttccaaagat aatggaacgg tggctgatag
    17701 acttgtcacc tgggacgcgg atactgccat gtaagtggct aatgtttgtt tttagtttca
    17761 tactggacct catacttgca atacttttac ctattttatc ataaaaagcc agaaattcct
    17821 taaaaattcc tgactttagg atagttattt tcttatttta gcaattctga aactggttcg
    17881 aaaacaattt tttcaatgtc agaaaggtaa atggccaatt gttgttgctt agtaaagaat
    17941 tctgacaaga ggctatttcc ttgaatctgc ttgccaaagc cttccatctt agcttggaag
    18001 gacgcatctg gcatttgacc tgtctgtgct agtttttgaa tttcctcttg aaaggcaaga
    18061 taatctgtaa agattttgct tgcctcagca tctgctgcaa tcgcatcttt agctgctttg
    18121 acagccttgt attctggtaa ttcgcgtaga ccgcgactaa gttcgtttgc actatcgtaa
    18181 atatttgaca tgattttctc cttatttgac aacgactgtg tagtcggtat tttctgttat
    18241 gagatgctca gctctttcca agtcttgagc atttttaaat gaaatttgta gaatcccgtg
    18301 aatatcctca cggttttcct cgttgatatg aatattgacc aaggaagttc cacgtagtag
    18361 ttccaaaatc ctcaagatga catcttcttc atcgggaacg tcgacataga ggtcgtaaga
    18421 actatccaca cctccacgct tatggatttc catggcctga cgttgttcac gcgcttggtt
    18481 aaaaaagttc caaatttgct cttcatctcc cttactaatg gcctgaccaa tcgcttccaa
    18541 acgttccttg aaatcctcaa ttctatccag aatgatctcg ctattggaca agagaatgga
    18601 ggtccacatt cctggctcgc tttccgcaat tcgggtcata tctcgaaaac cacctgccgc
    18661 aaagcgcctt gccatctcat gctcttgagc atagaccgca gtctgctcca tgagactaga
    18721 agccaaaata tgaggaaaat ggctaatctg agaagtgaca cgatcatgct ccttggcatc
    18781 aatctcgata aaacgagcat gaagacctga aagcagatcc ttcatttcct taagcgtgtc
    18841 ctgacttgtc aggcttgaag gtgtaaagat ataataggca ttttcaaaaa gattgacatc
    18901 tgccgaagca gcccctgtct tgtgactacc agccatggga tgggccccga caaagcgaac
    18961 agacttgcca gccaaatact gctccgccgc atccacaatg gttgacttgg tcgaaccagc
    19021 atctgaaata ataacgcctt ctcgcaaatc caaattggcc aactccttaa tgaaagcaat
    19081 agtttgtttg attggcaagc tgaggataat gacatctgcc aaaggagcaa aactagcaaa
    19141 atcatccgtt gcacggtcaa tcataccttc tttcaaggcg atatctctcg aagcttgact
    19201 acgattataa cctaaaattt cataatctgg atgatcgcgt ttgataccaa gtgccataga
    19261 ggctccaatc aacccaagac ctgcgatata gattgttttt gccataggaa ctccttaata
    19321 gttctttgta tagtctcggt gtttggctac cgcttctttt agttcctcaa gattatctga
    19381 tgagaatttt tcgaggattt cttgcgccag aaccgttgct acaactgctt ccatgaccat
    19441 tcctgcagct ggaagagcag tcggatcact tctctccacg gttgccttgt aaggttcgtg
    19501 ggtttcgata tccacactca taagaggttt ataaagagta ggaatgggtt tcatgacccc
    19561 acgaacaacg atgggttgcc cattagtcat accaccttca aaaccaccta gattattggt
    19621 acggcgagta taaccgtctt ctttagacca gagaatttca tccataactt ggctgccttt
    19681 acgataacca gcctcaaagc caagaccaaa ttccacccct ttaaaggcat tgatagagac
    19741 aacagcttga gccaatcttg catccaattt tctatcccat tggacatagg aaccaagacc
    19801 aactggaacg cctccgacga ctgtctccac aaccccaccg atggtatcac catcacgttt
    19861 gatttggtca atatagtcct tgatttcctg ttctcgttct tggttgacaa tagaaacttc
    19921 agactgggca gctctttgct taatttcagc gactgtcaga ttttcaggaa catctatttc
    19981 cttaccacca aagaccacga catggttggc aatctccata tccagctcag ccaagaggcg
    20041 tttggctact gcaccaactg ccacccgcat ggtggtttca cgagctgatg aacgctccaa
    20101 agaatttcgc aaatcatcaa aacggtactt aatcccccca accaaatcgg catgacctgg
    20161 gcgaggatga gtaattttcc gcttgctttt aaggcggtct tcaatgtcct ccgcagacat
    20221 gatgtccagc catttctggt ggtccttatt gatgacatcc atagtaatag gcgcccctgt
    20281 cgtcttcccg tggcgaacac ccgaagtaaa gacaacctgg tcactctcaa tcttcatacg
    20341 accaccacga ccgtagccac cctgacggcg tctaagatcc tcattgatat cctcagctgt
    20401 caatggaagt ccagctggaa ttccctcaat aatagctgtt agacgggggc cgtgtgattc
    20461 tcctgcagtt aaatatctca tacactctcc ttattttacc aagtagtctt tcatctcttc
    20521 cagagaaact gggtgaatgg tcgctgaacc aagctctggc accaagacca atttcaaggt
    20581 gttaccacgc gctttcttgt catgagtaag agcctgataa agcttgtcaa ctttccaatt
    20641 ttcatagtca acaggcaagc cgaatttctg acacatctct gtgatagatt gggtaatgcc
    20701 agctggcatg aggccttttt cctcagcaac cttggaaatc tgtaccattc ccatggcaac
    20761 agcctctcca tgcatgacct tgccataacc ggcagtcgct tcgatggcat ggccaatagt
    20821 gtggccaaaa ttgaggtaaa gacgaatacc attgtccaac tcatcttcaa ccaccatctt
    20881 gcgcttcacc tgacaagaat gttcaatcaa ggtctctgca tgttccaaaa tactctcaac
    20941 agaaccattc agtcccgtca agagagccca cagttctgga tcctcaatca agccatactt
    21001 gataacttca cccatccctt caatcaactc tctttttccg agggtttcaa gaacaagtgg
    21061 atcaatcaga accccatctg gttgggcaaa ggtccccacc atatttttag caaatggtgt
    21121 gttaacgcct gtctttccac cgatagaaga atcaacctga gctgtcaaac tagtcggaat
    21181 ctgaacaaag tgaatacccc gcatataggt agaggctaca aagccagcca ggtccccaac
    21241 aacgccacca ccaagagcaa cgattccatc gctacgagtc agaccttgct tgactagaaa
    21301 ttcatagact ttctgaacag tagttaaatt ctttctttct tcaccttcta agaaatcaaa
    21361 aacagctacc tgaaaaccag catcttctag gctgagcttg accttctctg catagagaga
    21421 ggctacatgg ttatctgtca caatgactac cttttgcggt tgccagagtt ctcgcaacca
    21481 ctgaccagcc tgggccatac aacctttttc aatctgaata tcataaggat gatgaggaat
    21541 atcgattctg attttcatag gagagtctcc ctttctttat tggtattttt ctgttaaaga
    21601 ctgccaaatc tcttctgtcg gcatttcctt gcctgtccac agttgaaaag cttctgcagc
    21661 ttgatagagc aacattccca gaccattgac tgctggattg ccctgacttc tagcccattt
    21721 caaaaacggt gtttcaaagg gttggtatat gatatctgca actaagagag tttctggtaa
    21781 gactatgttt tcaggaacag gagaggattg gccatccatg cccacactgg tggcattaac
    21841 tagcaaatcc gactcggcaa tccttgcttg cagttcagaa acatattcta aagcacacaa
    21901 atccacttta aagcctgtct gctcctgtaa cttgtctagg taaggtcttg ttttttccat
    21961 agaaacggaa cgaacaaaga ccgaaatctg actgacgcca tccaaaatag cctgtgccaa
    22021 gattgattta gccgcaccac ctgcacccag cagggtcatc tttttacctg aaattgtaaa
    22081 agaaggcaag cacttaaaaa atcccttgcc atctgtatta tatccaatta aattgccatt
    22141 ctcattgaca accgtattaa ccgcaccaat caagcgcgct tcatcgctta gctcatccaa
    22201 ataaggaatc acctgctcct tatagggcat ggacagattg atgccaaaca tctggtagcg
    22261 acgaatattg gccactgttt ctgccaagtc actcgcttca atctcccaag ccacataagc
    22321 accgttggta gctgtcgcct caaaggctct attgtggatg aagggagaaa tagaatgctt
    22381 aataggattg gcaacaactg cagctaaacg tgtatagcca tcaagcttca tccaaaatct
    22441 ccctgatttt tttcatgcta gctagagaaa tctgcccagg ggcactaacc tcatccagac
    22501 tggcaaaaga ccaactcgaa ccagtcacat ccgcagtgat acgagagacc ttgcccacct
    22561 tacccataga aatggtcaca tattcctgtt caggattgag ggttttaaag cctcgtgtat
    22621 agttcatcaa gtctaagaca tcctgctccg tgtgagccat caccgcaacc ttaacaagtt
    22681 ttggatttag gatcgtcaac tctgacaaga tttccatcat gttctcaggt gtttcttgga
    22741 aattatggta actcaaaaca agatttggga agtccagcat ttcctcaaaa acatccttgt
    22801 agctatagta ctcaaaatca atatagtctg gttgatagag ttgcgcaact tccttgatta
    22861 gatggatata ctcttctgga gaaaggtcga tttctccacc ttcggagcga gttcgtagcg
    22921 tgaaaaccaa ctcacggcct gcgaattttt caaaaatggc tggagctacc tgcaaaatcg
    22981 cttctttagg cagatagtcg gcacgccatt caatgatgtc ggcatccagg tacctcgtgg
    23041 catccagagc ctgagcctcc tctaaacttc ttggcattac tgaaacgatt aatttcattt
    23101 actaaccttc atactaatca ccttgaggta attactactt tcatcttttt tattataggc
    23161 aaaatctgct ggaagaccat atttgtttaa aatctggtaa cttcttcctg caaagccttt
    23221 atcaatttgt tctgtaaatt tctggcggga aacattggca gcattggtac tggcaatgat
    23281 aatccctccc ggatttaaaa tctcaagact ctgggaaatc aacttgtgat aatccttggc
    23341 cacagagaaa gtttgttttt tattccgagc aaagctaggc ggatctagga caatcacatc
    23401 gtaggtcaag tctttgcgtt tggcatattt gaaatactca aagacatcca tgactataaa
    23461 acgatgctcg tctgtgctga gcccatttgc ctgaaaatgc gcttgagaca attctcgtga
    23521 acgtttggct agatcaacag aagttgtctg gctagctcct cccatggccg cagctactga
    23581 aaaagccgct gtgtaggaaa acatattgag caaggattta cccatagcca agccgtcaac
    23641 taaactaccg cgaacctcat gctggtctag gaaaattcct gtcatcaaac catcattcat
    23701 aaagacttga tacaggacac cattttctaa aacagtgaaa aagtcaggtg cttcttgacc
    23761 ataaacatgg gcagattcat agtccaaacc tttaaagcgg attttctcat aagcccctaa
    23821 aacctcaggg aaaacctgtc taaaggcttc tgatatagtc tgacgaatct gataaacata
    23881 agagttatac caagaaaaga cggcgtagtt gccataaagg tccactgtca gacccccaaa
    23941 gccatctccc tcttgattaa agagacgata ggtagttgtt aaatcatctt gatagtaggc
    24001 gcttctcttt tctttggctt ttctaaacaa cgtttcaaag aaagcttgat tgaaggccac
    24061 cttgtctttg ctgacaaacc agcccaagcc cttgttttgc tgagaaaggt aggcagtccc
    24121 aagaaagttt ccttcctgac cctgcacctc tacttcctga tccttaagat tgacattctc
    24181 aagatcactg gcttctagta aaactagccc cttagcaagc ttcttttcaa cccttttgct
    24241 gactcttatt ctattcataa ctaccattat atcaaacttt tagacaattc tcaaaaaaga
    24301 aactaccctt gcttttttac tcttctttta aaaaatggta tactagactt cctgcaaaac
    24361 taggaagtaa atgtgtaaga atcacaataa aaaatgctct tccgtcttgg aggagcattt
    24421 tttttatcaa cgaaaatcaa atagcaaact atgaaactag cctcaggtta actgtgatat
    24481 tataggtaga gaggttgtat cagcaatatg tgtctgtcaa atttagtgac aaaggtagta
    24541 gaagaaagat gaataaataa atcagcttca gtagatatct ggaaaatttg attttataga
    24601 gaagcctttt gttacaaact caatatacta tcaataaata atattataga agcaacaata
    24661 attataattt cacctatctg catcattcta tttcgaattc taaatatatg ttctatcaag
    24721 aatacttgga acacacacat tataggaatt aacgtttttg aaattgaaaa atatccaaat
    24781 aaataaacta taaacaacaa aaatagaact atgttatatt tcttattcaa aacattcctc
    24841 cctatatttt tgattaccaa tcttaatcat ttacaactac attctaacaa actataaaag
    24901 cgtttgtcga attgaattta tcaagcaagc gaccaaccag ctcatctttt ttctatttct
    24961 gccaatatgc gtgacaggta ataatgatag ccaaaaatag caagagcaag caggaggata
    25021 agagctccta ctcccaagct gatggcaagg atagtggaga gagactgaac caagaatatg
    25081 ctcccaatta caagggccat caggattgca ctataaataa acaataaaac tatggcgact
    25141 atgccatttg aacgattcac caggtccgta atgctactcc aattggttga cagattttta
    25201 acgtccttaa agtaatggtg gcaagaaagg atgacactgg caaggatcca tgccacaata
    25261 aggtaaatca tcgaaatgat gggcaagcct agatatagag aaagaccaag caaagtcaga
    25321 actggtaaaa aggactggac agcatatata atccaaaatt tcactttcac ataacgagca
    25381 aagtcaaagg gtaaactctt aagaaaatca acattttccc tctccaagga caaggcaatt
    25441 gaatgcaggc tggtgatatt gttattgaca actgctataa agagagctat aaaaaacaag
    25501 ggtaaccagt atggaggatg aatgtctgga actatctgag aatctcggat tttggaaatc
    25561 agaccgatca tcatgagata aggaaagaaa gcacttgtaa aaagcactgt aaccacgcca
    25621 gtaccctgtc ccaagagggt gaggtggtag cgtaaaacca tgcgaaaaaa tcccttttta
    25681 gtggttgaaa ttctctcctt gctgcgacgt tcttttttga ccttatcctc actattaagc
    25741 aggatcacgt cataaaaacg aggaaggacc ttctttttgg tcagataaag caggaagaga
    25801 gttagtccta tccaagcgag cagacccact aaggcttctg tcgaaaaagg ctccactgct
    25861 attttgtaaa agatatgaag aggataaagg agaaatggaa tgtctctaac tttgtcaaca
    25921 atacttccaa aagtcgactg aagaaagaag ataaatatta aaggtatgag aactcctatc
    25981 ccaatcatca cattcgaaaa aatagactga tactttctga agaccctagt ctgagccaag
    26041 aaatgtactg ccactaccat cactaaagta acagagacaa ataataaggt caaggacagt
    26101 agcatcaaag gcaaacccaa ccacagagaa ggtgctagcc taatgtatag gaccagaaaa
    26161 taagctagga ttggtacaat tccagctaga gctggcaaga ggacagacag acctttggcc
    26221 attataatct ctgattcttt aaaggcatag ggcctatagg aggccaggtc cttactctca
    26281 taaaagacat tgtaaaatgc agtgaaagaa gttgaaaagg ccagcaccag taaaatagca
    26341 accatcgtac taaaaaaact tggcatttcc tcaaaaggaa aacgaaaggc tatatttata
    26401 aacatgaaaa gcatcaagag actggaaaaa atgtaagaac ttaggactct agcggaaaca
    26461 tttacttttt ttccagtatt tttagcttgc ttctttcgta ggttagccag attagcttct
    26521 tgagatgaat agaggatatt gatatcaact aattttttaa tgaccttgag acgcatctga
    26581 aacctcctct tttctaccag caagactaag gtagatactt tccaaagact ggtctgggta
    26641 atcttttctc aagtcctcta cactaccaca ataaatcaaa tgcccctttt tcaaaatggc
    26701 aatccgatca cagacttgct ctgccacctc taggacatga gttgaaaaca agactgtctt
    26761 ccctttttgt gcatgttcct tcatcatctg tttcaaatca aaggcagcct ggggatccaa
    26821 accagtcaag ggttcgtcca agacccaaat atcaggatca gacaagagtg ccccgatgac
    26881 aaaaactttc tgacgcattc catgagaaaa ggtttcaata acctgataac gattttcagc
    26941 aaaatcaaaa acgttcaata gcctagctag actagtctcc aagtcagagc tagtcagatc
    27001 ataggatgag gcgatcaatt cccaaaattc attggccgtt aaacgtaaaa ataagtcagg
    27061 cgagtctgct acgtagccaa tctttcgttt gatcgccaag cgattttccg ataactcctg
    27121 accatctacc aaaatacgac cactgctggg tgaaatgata ctgactaggg attttatggt
    27181 ggtcgatttt ccagccccat tatgaccaat caagcccata atctctccat tttcaatctg
    27241 caaattgaga ttactcaagg cctctttatc accatacaac ttactaacat tttgaaattc
    27301 aatcatggga tgactcctat ctttatctgt attatacatc gctatactag cactttgata
    27361 caaaaaaatc aatactttat tttaagtagt taaaatagtt tccttctatc ttacgcaaac
    27421 gtttgctccg agagatactt tatgatagaa taaagaacaa gattgacaag taagaggaaa
    27481 catcatgcaa aatcaaacac tcatgcaata ctttgaatgg tatctgcccc acgacggtca
    27541 acactggacg cgtctggctg aaaatgctcc acacctagct catctgggga tcagtcacgt
    27601 ctggatgcca ccagccttca aggcaaccaa cgaaaaagat gtcggctatg gggtctatga
    27661 cttatttgac ttaggagagt tcaaccaaaa agggactgtc cgcaccaagt atggtttcaa
    27721 agaagactat cttcaagcca ttcaagccct taaagcgcag ggaattcaac ctatggccga
    27781 tgtagttctc aaccacaagg ctgctgctga tcacagggaa gcctttcagg ttattgaagt
    27841 ggatcctgta gaccgtacag ttgaacttgg agaacccttc accatcaatg gctggactag
    27901 ttttaccttc gatggtcgcc aagataccta caatgacttc cactggcact ggtaccactt
    27961 cacaggtaca gactatgatg ccaaacgccg taaatccggg atttacctaa tccaaggaga
    28021 caacaagggc tgggctaacg agggattggt cgataacgaa aacggaaact acgactacct
    28081 catgtatgcc gacctagact ttaaacatcc tgaagtcatc caaaacatct atgactgggc
    28141 tgattggttc atggaaacga ctggtgtagc tggtttccgt ttggatgccg ttaagcatat
    28201 tgactctttc tttatgcgca atttcatccg cgatatgaag gaaaaatacg gtgacgattt
    28261 ctatgttttt ggtgaatttt ggaacccaga caaggaagcc aatctggact atctcgaaaa
    28321 aacggaagaa cactttgacc ttgtcgatgt tcgtctccac cagaatctct ttgaagccag
    28381 tcaagctggc gcaaactatg accttcgtgg cattttcaca gatagcctgg ttgaactcaa
    28441 gcctgacaag gctgtgactt ttgtcgacaa ccacgatacc caacgaggac aagcccttga
    28501 gtctaccgtt gaagaatggt tcaagccagc agcctatgcc ctcattttgt tacgccaaga
    28561 cggccttcca tgtgtctttt acggagacta ctatgggatt tcaggccagt atgctcaaga
    28621 agatttcaaa gaaatccttg accgcctcct agccatccga aaagatttgg cctatggaga
    28681 acaaaatgac tactttgacc atgctaactg tatcggttgg gtacgttcag gtgctgaaaa
    28741 tcaatcccca atcgcagtct tgatttcaaa tgaccaagaa aacagcaagt caatgtttgt
    28801 cggtcaagaa tggactaatc aaacctttgt agatttactt ggtaaccacc aaggtcaagt
    28861 tacaattgat gaggaaggtt atggacaatt ccctgtctca gctagatccg taagtgtctg
    28921 ggcagtcaat accatctaat agctcataat aaccaagcta ggtccaagcg gatttggctt
    28981 ttttgtagtc aaaaaagacc tacccaaatg gatagatctt tacttgatta caatttacct
    29041 gctactgcat ccaataattc ttggatctta gcttggttgc ttcctcctgc catggccatg
    29101 tctggtttac caccaccacg tccatcgatg attggtgcta attctttgac aaggtttcct
    29161 gcatgaaggt cttttgtctt gcttgctaca aggacattga ctttgtcacc gatagcggca
    29221 actaggacaa gaagatcaga gtagtctttt tgtttccagt tatctgcaaa agtacgaagg
    29281 gcaccggcat cggatacaga cacttgacta gcaatgtaac gatgaccgtt gacttcctta
    29341 acatctttga agatatcgcc tgcggctgca gctgcggctt tttctttcaa ctcagcattt
    29401 tctttttgaa gttgacgaag ttgttcttga agtccttcta ccttgtgagg tacttccttg
    29461 acttgaggtg ctttcaaggt tgctgcgata gctttaagag catcctcttg ttcacgatag
    29521 gcttcaaagg cttccttacc agtcactgcc aagatacggc gagttcctga accgattcct
    29581 tcttctttga caattttgaa gagaccaatc tcagaagtgt tgtcaacatg agtaccacca
    29641 caaagttcaa tagagtagtc accgatagtc acgacacgaa cttccttgcc gtatttctca
    29701 ccaaagaggg ccatagctcc catttcttta gcagtgtcaa tatccgtttc aactgtcttc
    29761 acttcaagtg cttcccaaat tttctcgtta acttgctgtt caatcgcacg aagttcctca
    29821 gcagttactg cttggaagtg ggtaaagtca aagcgaagga attcaacttc gttaagagat
    29881 cctgcctgtg ttgcgtggtt tccaaggata ttgtgaaggg cagcgtgaag caaatgagtc
    29941 gcagtgtggt ttttcatgac acggtgacgg cgattgctat caattgccaa ggtatattct
    30001 tggttcaagg caagcggtgc aaggacttca actgtatgaa gggcttgacc atttggggct
    30061 ttctgaacat tggtcacagt agccacaacc ttacctgact catccaagat ttgtccgtag
    30121 tcagctacct gtccacccat ttcagcataa aatgacgttt ccgcaaagat aagagaggca
    30181 gttccttctg aaacagctcc tacttctgca ttgtcagcaa cgatagctac caatttagaa
    30241 gacaattggc tagcattgta gttgaagaca ctttctacag tgatgttttg aagagtttca
    30301 ttttgcatac ccattgagcc acccttgaca gctgacgcac gcgcgcgttc ttgctgttct
    30361 ttcatggctg cttcaaaacc ttcacagtct acagtcatac cagcttcttc agcaatttct
    30421 tcagtcaatt caactgggaa tccgtatgta tcatagagtt taaagacatc ttgaccagca
    30481 atgacagatt gacctttttc tttcaagtct gccacaatgc cttgggcaaa gtgttgacct
    30541 gagtgaaggg tacgggcaaa tgattcttct tcgctcttaa cgattttctc aataaagtca
    30601 cgtttctcaa gcacttctgg gtagtagctt tccatgattt ttccaacagt tggaacaagt
    30661 ttgtaaagga aaggctcgtt gatacccaat ttttgaccat gcatagaagc acgacggaga
    30721 agacgacgaa gaacataacc acgaccttca tttcctggaa gggcaccatc accgatagca
    30781 aatgaaagag aacgaatgtg gtctgcgata accttgaagc tcatgttgtc gccatcttgg
    30841 tcataaacct taccagacaa tttctcgact tcacggataa tcggcataaa gaggtccgtt
    30901 tcaaagttgg tcttagcccc ttggataaca gccaccaaac gctccaaacc agcgcccgta
    30961 tcaatgttct tatgtggcaa ttccttgtat tcgctacgag gaacagcagg gtctgcgtta
    31021 aattgtgaca aaacgatgtt ccagatttca atataacggt cgttttcaat atcttctgca
    31081 agcaggcgaa gaccgatatt ttctgggtca aaggcttccc cacggtcaaa gaagatttct
    31141 gtatctggtc cagaaggtcc cgcaccgatt tcccagaagt tgtcctcaat tggaatcaag
    31201 tgacttggat ccactcccac ttcaatccag cggttgtaag aatctttatc gtctggatag
    31261 taggtcatgt aaagtttttc agcagggaaa tcaaaccatt cagggcttgt caaaagctca
    31321 taagcccaag tgatagcttc gtcacggaag taatccccga tagagaagtt ccccaacatt
    31381 tcaaacatgg tatggtgacg cgcagtcttc cctacgtttt cgatgtcgtt ggtacggata
    31441 gccttttggg cattggtaat acgtggattt tcagggataa tggtcccgtc aaagtatttc
    31501 ttaagggttg ctaccccaga gttgatccac aaaagagttg ggtcatttac aggaaccaaa
    31561 cttactgatg gttctactga gtgacctttg gtcgcccaga aatcaagcca catttggcgt
    31621 acttgtgcac tagatagttg tttcatattg tctccttatt cacttgttta atgtgattgg
    31681 ctttccagca tttccacata gtcaatcgcg acacagaggg aaatgactag gtctgcataa
    31741 gcgtcctcaa gaaccgttac ggtataggta gaggtcagat ggaagagttc cttcttaatt
    31801 tccgcaatca actgatcgcg atcatccagc aatttgaaat tcaaatccca gatattgccc
    31861 tcgatacgaa gacctagatt atcaaactca tacttatctc gccaaaaggt caacttctta
    31921 cgaatgacaa aactcgagcc atcccgaagc tgaatctcaa aacgaggaag caaggtcaag
    31981 atttctttac tgatctgact gacttgttca ccagccgcat catagatggt aaaagttttg
    32041 ggaatcttaa aaaatgatcc ctccacctga taggcaattt ctcccctgtc atccttgata
    32101 gcgaagcgtt cgcctccaag acgaaacttt tgtttgacaa gaaatgtttt catcaacacc
    32161 tccaaaaatc aaaagacaag ctcatatcac gaagggcgaa aaaccgcggt accaccttca
    32221 ttcaatgaac ttgtcattct cttgttctta tgcaattgta tgattgagta gcatgacttc
    32281 ctagcttaga tggctcgcag caccgccatt tctctggact aagacaagtg aaaatcaatt
    32341 ctcaactttc ttattatatc gtttttttaa tcttgcgtca actggaaatg atctccgttg
    32401 aattagacca attccctaca tctctgatta ctttttcagg atatattttt tcttactgcc
    32461 gtttttcttt ttatcccaaa ttttcatatt actaaacaca gctactagaa tatttccaaa
    32521 tataaaggtg cctatcaccc aatatatgga ctcagttgtt aggtattgtc gatccaagcc
    32581 atcctttaaa tggaatagta tagcagtttg gttaacaatc ataaaggttg gccagaaact
    32641 tttgttgaaa aaagtagaca ttttcattat ttgttgccgc tttctgtaag gttaatactc
    32701 aataaaaatc aaaaagcaaa ctaggaagct agcctcaagc tgtacttgag tacggcaagg
    32761 caacgctgac gtggtttgaa gagtataggc ttagtatact actaggcaag caaataagca
    32821 aataaacaac tagaatagaa aaagataggg ctctaaaaac tgacttctat tccttaaaaa
    32881 cgaaccagct tgactgattc gtcttcttac atttatctcc tacttccgat acattttaaa
    32941 ctgtaggaag aggtcgctat atttccctgt ccatttatgg tcaaatttct cataaacttc
    33001 taggtgtttc atggtttcaa catcgggata gaaggcctta tcttcctttg tttcctctgg
    33061 gagcaattcc ttcgctggta ggtttggtgt tgaatagccg acatactccg cattttggag
    33121 agcattttca ggtttcaaca taaagttgat aaaggcatag gctgagtttt ggtttttaac
    33181 tgttttggga atgaccatat tgtcaaacca aagattgctg gcctctgtcg gtaccacata
    33241 acgtagattt tcattttttt ctaacatttg gctggcttca ccagagaagg tcacgccgat
    33301 tgcaacatta ttctgaatca tatagccctt catctcgtcc gcaacgatag ccttgatatt
    33361 tggagtcagt ttgtagagct tatccactgt ctcttccaac tgctgcagat ccttggagtt
    33421 gaggctgtag ccgagggaat tgagtcctag tcccagcacc tcacgcgccc catcaaagag
    33481 catgatagaa ttcttatact ccggcttcca aaggtcatcc caatgctcag gcgcttcatc
    33541 taccatggtt tcgttgtaga caattcctaa ggttccccag aagtaaggga tggagaattt
    33601 attacctggg tcaaaggact ggttgagaaa ctctggtccg atattttcga ttccttcaat
    33661 ttttgaataa tcaagcggaa ccaagaggtc ttcgtccttc atcttgttaa tcatgtattc
    33721 acttggaatg gcaatatcgt aggtcgttcc accctgcttt atcttagtgt acatggcttc
    33781 gttggagtca aaagtctcgt actgaacttg aattcctgtt tcttctgtaa actgagtcaa
    33841 gagttcagga tcgatatagt ctccccagtt atagataacc aatttttgac tatctcgact
    33901 attgatttta ctatctaaat gagtcgcaat tccccacaag acaaggataa tcgctgcaat
    33961 tcctgctaaa aatgaataga tttttttcat gcttgctcct ccttctcacg agagataaag
    34021 taataaccta caactaggat aatactaaag agaaagacta gagcagacag ggcattgatt
    34081 tctaaggaaa tccccttgcg agcacgagag taaatctcga ctgatagggt tgaaaagcca
    34141 tttcctgtta caaagaaggt cacggcaaag tcatctaacg aataggtgaa ggccatgaaa
    34201 taaccagtaa tgatagacgg agtcaggtaa ggaagcatga tttccttgaa catctgaaat
    34261 tgactagctc ccaagtcata ggccgcatga atcatgtcgc cattcatttc cttgagtcga
    34321 ggcaagacca tcaagaccac gataggaatg gagaaggcca cgtgactaga tagaacggtc
    34381 aaaaagccaa gtgaaaactt gagttgggta aagagaatca agaagctagc accaatcata
    34441 acgtcaggcg caaccatgag gatattattg agtgatagaa aggcttcttg gtatttctta
    34501 cgagactggt agatgtaaat ggcaccaaaa gtcccgataa tggtcgctat caaggctgat
    34561 aggaaggcca agaaaaatgt ctgagccaaa atcagcatga gtctcccatc tccaaacatg
    34621 gtttcaaagt gagtccagct aaaacctgta aagctattca tatcatcacc agcattaaag
    34681 gcatagccaa tcaagtaaaa aatcggcagg tagaggacca gaaagaccag tcccagataa
    34741 aggttggcaa attttttcat cgttctctcc tttccttagt cacccacatg gtgatgaaca
    34801 tggtcaggat gagaatcaca ccgatagttg aacccatacc atagttgtca ttggttagaa
    34861 aattctgctc aatagccgtc cccaaggtga taacgcggtt cccaccaatc aaacgggtca
    34921 gcatgaagag actcaaactt gggataaaga ccgactgaac cccacttcgc acaccgttca
    34981 tagatagagg gaagatgaca tgacggaagg tctcccactt agttgcacca aggtcgtaac
    35041 tagcattgat gagattatta tccatttcgt ctaagacatt gaaaatcggc aaaatcataa
    35101 aggggagctc gatgtagctt gcgacaaaga taaatgagaa atcagtaaat agcaactgct
    35161 gtgaaccaat tccgataaat tccaagaatt ggttaataga gccattctga ccaaaaatcc
    35221 cgataaaggc ataagcctta agaagaaggt tgatccaagt tggcagaata atcagcataa
    35281 tccagagttg acggtgtttg agacgggtca aaaagagggc cgtcggataa ctgataagca
    35341 gtgtcacaaa ggtcacaatg cctgcataaa gcactgagtt gaaactcatt ttaagatagg
    35401 tcaagttttg tgacgcaaag taagatttgt aattttctaa actgaactgg ccttcgatgt
    35461 tgaaaaagga ttgaccgaaa atcaagacca agggtgccaa tacaaagagc gcaatccaaa
    35521 gcatgtaggg tactacaaag agtttagagc ttgttttctt catctctttc ctcctcgatt
    35581 gcattgatca aacctgcttc ttgctcttcg atttccacgt attcttcgat acgagcatcg
    35641 aactcttctt cggtttcatt gagacgcatg atgtggatgt cttctgattc aaagtccaga
    35701 ccgatttcct cacccacgat ggccttacgg gttgagtgga tcatccattc atttccaagt
    35761 tcgtcatagg cgataatttc ataatgaact ccacggaaga gctgggtgtc gaccttaact
    35821 tggagcttgc cttcttcagg aagggtaatg cgcaagtcct ctggacgaat aacgacctca
    35881 acaggttcat ttggcttcat cccaccatca accgcttcaa agcgtttgcc gttaaattcg
    35941 accaagtagt cctcaatcat ggtacctggc aagatgtttg actccccgat aaaggtggca
    36001 acaaagtggt tgattggctc atcgtagatg tccacagggg ttccagactg gacaatctcg
    36061 ccatcattca taacgaaaat ccagtcactc atggcaagag cttcttcctg atcgtgagtg
    36121 acaaagacaa aggtaatgcc caatcgttgt tgtaattcac gcaattcgta ctgcatgtct
    36181 gttctcaatt tcaagtccag cgctgataaa ggctcgtcca acaagaccac acggggttgg
    36241 ttgatgatag cacgggcgat ggccacacgc tgacgttgtc ctccagaaag tttgcggatg
    36301 gaacgttttt cataaccttc caactgaacc atcttgagaa cttccgctac acgctgctcg
    36361 atttctttct tatcaatttt acgcaagcga agtggaaagg caacattttc aaacacattc
    36421 atatgtggga acaaggcata ggattggaag acggtatgta cgtcgcgctt gttggttgga
    36481 atatcattga tacgaacacc gtctagcatg atatctcctg tcgtcgcatc cagtaaacct
    36541 gcaataatgt ttaggatagt tgatttcccc gaaccagatg cacctagaag ggtgtagaat
    36601 ttcccttctt ccaactcaaa gttgatgtct ttgagaacct tggtgttgct gtcttcaaaa
    36661 actttagaga cgtttttgaa ttcgataatt ggttttttca attggcataa attccttctt
    36721 tttcatagat taaccgatcg gggctctgtc aggtccccac tacctcttgc agggagtaaa
    36781 accacctgca tacatcttcg ctaccgatag gctttcatcc cctttccatg acatagcagc
    36841 agcttttcaa atacagcttc ctacttgctt tcacccaaga tccggacttc tctttcaagc
    36901 gtaatacctg agtgttcctt gactttttcg ataaccgatt ggatcaagtc ctcgtagtct
    36961 ttggccgttc catctgcgac attgatcata aatcctgcat gcttttctga cacttctacg
    37021 ccaccgatac gatagccttt caagccagct tctgaaatta actgacctgc aaaatgcccg
    37081 actggacgct taaagaccga gccacaagat gggtattcca aaggttgctt gagttcacgt
    37141 aggtgcgtca agcggtccat ttcctgcttg ataacctgat gggttcctgg ggctagggca
    37201 aatttaactg acaagacaac tgcaccagac tcctgaatag ctgaatggcg gtaaccaaaa
    37261 gccaagtctt tagcagacag ggtttcgatt tctccatcct tggtcaagac cttacaagac
    37321 tgcaagatgt gagcaatctc gccaccatag gcacccgcat tcataaagac agcaccgcca
    37381 acgcttcctg gaataccaca agcaaactca aagccagtca aactatgacg gagggcaatg
    37441 cgagttgttt caatcaagtt agccccagct tctgcttcaa tggtatagcc atcaacagaa
    37501 acgttattga gcttgtcaca caagatgaca aatccacgaa tcccaccatc acgaacgatg
    37561 atattgcttg cattgccaag aaccatccaa gggatatttt cttggttggc aaatttcaca
    37621 aggcgcgcca actcaaaacg atttcgtgga aagaccaaat aatcagcctc tccacctact
    37681 tttgtataac tatagctatg caagggttcc ttaaaacgga tatcaattcc ttctaagatt
    37741 tcaagcattt tttctcttac agacatgtca ctcttccttt tacaaaattc attccattat
    37801 accattttta gagacatttg acgaccataa aaataccttg tttggatttt gcataagaaa
    37861 aagagtttcc ccccttttta tgatttttta caaaagattt ccttggttcc ataggcgacc
    37921 agaacgagct ccagtgctag aatcacttca accaagactg gatttgtcaa ccagcctact
    37981 tggaaaagag atggtgccag atcaaagaag gcatgcaagc cataggctgc taggagataa
    38041 atccatttct tctggcgaac agcttggtaa acccaaactg tcaaaagtaa ttggaaacca
    38101 agcgccaaga ttcgctcaaa accaagcaaa taaatctgcc agaccgaaag tgactgaatg
    38161 gtttttaaca tattttcaga cagtaattgc ataacctgtg gattctgagt ttgaactgcc
    38221 gaaagaacga tgtaaagatt gagtaaacta ataaggccta gaaaaatcaa ctccaagcca
    38281 ccatgcccta ggccataggc caaggcatct gccttttcca aacttctctt tttctccaac
    38341 catttgaaga aaacaagacg agccgtttcc tcaaaaaatg ctgccatggc taggccatag
    38401 ataatataga taagcggatg atcttgcaag agggcaatac tagcgtcttt ttgagggtgc
    38461 aaaatcaaga tatgcaccag tttttccaaa atctgcgaag agacaaagaa agcgactgca
    38521 cccaagccca agacagctag attaatctgg tatttctttt tggcaaacca aatgcttcct
    38581 atcagaaaag ctagcaacag caacatggta ataatgatat gaatggtcat tttcttctcc
    38641 tattctgcct tttcaatatc ttttttcatc tcgtcaacat tgaacttagc aaacaagtat
    38701 tgacggtctt ggactgggaa acgttggtcc aactggtcaa ctgctcccac ctcgataatg
    38761 ccttccttga tgacaaaatc catgacatgt ccaccgaagg tcaaatcatc tgatatgaag
    38821 tgcagatggt agcctgccac actgacccca tggaaaatct caggcgtcca gaaaccaaca
    38881 atagtccccg caacattgtc acgactatat tccggttgat gggttgcgac atcagcaaac
    38941 ttggtatcgg gtgttgactt aggaatcata cgcacatgca tatgtaaaaa ttccccccga
    39001 atcttgatag agcggaaaag attttcccca tcataataag actcaattcg ttctttcaat
    39061 tccttgtctg tcatctcaaa gcgctggcgg aaaatgacct ctgcctgatg cggtaccact
    39121 gcagcgtaag gaataagggc atctggtgac acttccacaa tttctggctg gtctcctgac
    39181 cctttggcct gataagcctt gccatccaag acaatcaatt ccccatcaat ggaatccaag
    39241 gttcccaaac caaggtcacc atgttctagc aattctccta ctgtcatagt accaccataa
    39301 aggccagcca tcaaggctcc aagagtattg tattgaaata atttcactgg ttcctgcacg
    39361 ttcttatcca ttcactttct tgtctgttat tctataaatc ttactcctaa gtataccaca
    39421 tttgccccta gatgtgaacg agagaaacgc tctagacatt gccaagaagg aaaaaaaagg
    39481 gtacaatgta acaaaatcaa gggaggtctg gaatgaagaa acaaagcaag tacaaagagg
    39541 tcgtttccta tctgaaaaat ggtatcgagt ctggacgatt tccgacgggt agtcgcctgc
    39601 cttctatccg tcaactgagc cttgactttc actgcagcaa ggacaccatt caacgagccc
    39661 tgctggaatt acggcacgaa caatacctct atgccaagcc tcagagtggc tactatgtat
    39721 tagaacaagg gcaacatcaa gacctagaaa tcgaggttac cgacgaacat gccagtgcct
    39781 atgacgattt ccgactctgt gtcaatgaaa ccttgattgg ccgagaaaac tacctcttca
    39841 actactatga caatcaagaa ggattagaag acctaagaca gtccattcac aaactcctct
    39901 ttgagcaagc tctctactgc aaggctaacc aactagtact gacttctgga acccaacaag
    39961 ccttgtttat cctctctcaa atatcctttc ctagacaagc caaggaaatc ttggtggaac
    40021 agccaaccta ccatcgaatg aatcgcctct tgattgcaca ggggctggac tatcaaacga
    40081 ttgaacgagg cattgatggg attgacttgg aggagctgga aggccacttc aaaacaggaa
    40141 aaattaagtt tttctacacc attcctagat ttcactatcc tctgggacat tcctattctg
    40201 agcaggacaa acgatctatt cttaacttag ctgccaagta tgatgtctat atcgtagagg
    40261 acgattatct gggtgatttg gactccaaga agggccaaac cttccactat cttgatacag
    40321 aggagcgtgt catttatatc aagtccttct cgaccagcct ttttcctgcc cttcgtatta
    40381 cagcactcat tcttccaaat gctatcaaag aagcatttgt ggcctacaaa aatatcctag
    40441 actacgacag caacctcatt atgcaaaagg ccctgtcact ctatattgac agtcaattgt
    40501 ttgaaaaaaa tcgtttggct cgcttgacca atcatgaatc ttaccaaaaa caaatcgagg
    40561 aaaggataac taaaacacct tgtctccttc ctcattatcc cctacacgat ggtttattgc
    40621 tagacctgag acagtatcct aaaatcgcca gtctcaaaca cagtcaaccg ggcttggact
    40681 tctttgaaga ggcctattta agtacctgtc cttatcaatt tgccaaggtg tccctagaca
    40741 atctggaaaa tgttttaaac tatttaaaag cagaattgga atgacatcca actctgcttt
    40801 ttcttattct tcaacttcag ttagacttgc tgctttttca agatagcttt ggtaagttcc
    40861 ttcatcctta agtttttgga tgaccttgtc taccacttct ttcaaatcat cactattttt
    40921 tctaagagca acggcattgg cgtcgccgtc cttcatcttc aagctgacag ttgcgacagc
    40981 taagccagcg tttttagcag cataactaag tgcaacaggc tcatccatat gaacagcatc
    41041 tatttttcca gtctgcaatt cattgactgc ttcacccata ttagttaggg aagttaattg
    41101 aacttttggc aattgttcct tgaccattga ttctggaaca gtcccttttt gggctgcaat
    41161 attagcactt tctaggctag ttaaatcctt gtatttttcc acatcagcct tacgaaccaa
    41221 gaaactaatc ttgttttcat agtatgggat tgaaaaatca aagacttctt ttctctcgtc
    41281 agtagcacta attcctgcaa ctgctaggtc agccttacca gtttgaagac tggtcaaaac
    41341 attgtcaaaa ctcatgcttg agatttccaa cttaacccca agttcatcag cgatagcctg
    41401 agccatgtcg atgtctgcac cgactacctg gttctttcca tcaaccaatg attgaaattc
    41461 aaagggtgca tagtcaggac tggttgccac aactaatttc cctttttgtt tgatagcatc
    41521 cacagcagac tgagaaccat tagaacctga ctgacaagct actaagaaga aacttgcaag
    41581 aaaattacat aaaacaaata tccatttttt tgatttcata aataaacaac ctctctgtta
    41641 attttgtata attataacga tatccaagtt acttgtcaag tgttttttaa atttttatct
    41701 caaaaatatt ttttcgttca aaaaaaggag ccatcagttg atttcaagct cctttttata
    41761 cagaattaaa ctattttata gttcgacaat cttacctgtt tcaaagtaga caacccattc
    41821 acagatattt ttagcatagt caccgatacg ctccaagtag gaaataactt ggaaataatc
    41881 acgacccgta acaatggctt ctggattttt cttaatctct tcagtcgcaa ggtcacggat
    41941 agtttcaaaa tagtggttaa tttgctcatc catggaggcc acccggtatg cgtcgtcaac
    42001 agaaccatta agataaagat caagtgctgc ttcaacaacg cttttaactt cacgtcccat
    42061 ttttttaatt tcttcctcta cagctggaat gcgctcttcc cccttcatac ggatggttgc
    42121 ctgggcaatg gctacagcgt gatcccccat acgctccaca tctgatacag ccttaaggac
    42181 agtcaagact gtacgcaaat cttgagagac tggttgttgg agtgcgatca tttcaaatga
    42241 tttcttttcc agtttcactt cgtattcatt tacttctgca tcatcttcga tgacctcttt
    42301 tgccaggtca cggtcatgcg tgacaaaagc acgtaccgta cgattgattt gtgagagcac
    42361 ttcttgtccc atagcgtaga actggttatg taatttctct aaatcttctt caaattgaga
    42421 tcgtaacatc tttcatctcc ttatccaaat tttcctgtaa tatagtcttc cgtttccttg
    42481 tgttggggat caaggaacat ctgcttggta tcattaaatt caatcaaatc tccatctagg
    42541 aaaaatcctg tcttatcaga gatacgtgaa gcttgctgca tggaacgggt taccagaagc
    42601 atggtgtact tgtcttttag accatacaag gtttcctcaa ttttaccagc tgaaatcgga
    42661 tccaaagccg aagttggctc atccaagagg atgattttag gactagttgc caagacacgg
    42721 gccacgcaga cacgctgctg ttgaccacct gacaatccaa tagctgaatc atatagacga
    42781 tccttgacct catcccagat agaggcacct tgcaaggctt tttctacggc ttcatccaga
    42841 acctgcttat ccttaattcc attgatacga agcccgtaga caacattctc atagatagtc
    42901 atagggaaag gattaggttg ttggaaaacc attccgattt ccttacgtaa ttcaaccgta
    42961 tctgtacgcg gactgtagat gttgtgacca ttgtacacca cggatccagt tgtggtcacc
    43021 tctggattga gatctcccat gcggttgaga gacttgagga gggttgactt ccctgatcca
    43081 gatggaccaa tcaaggctgt aatttcctta ggttggaaag atagggaaac actattcaaa
    43141 gccttctttt tattataata aacggacagg tctgatacct gtaaaatcgc atctgtcata
    43201 cggtttcctt tctaaccaaa gtgaccagat acatagtcat tggtggactg tagcttggca
    43261 ttttggaaaa tagttgcagt cttgtcatac tcaatcaaat cacccaagta aaagaagcct
    43321 gtatagtcac ttgcacgagc agcctgctgc atattatgcg ttacaatgat gatggtaaag
    43381 tttttcttga gctcaaacat ggtctcttct agttgcatgg tcgcaatcgg atccaaggct
    43441 gaggctggct catccattaa gaggatatct ggcttaacag agatggcacg agcgatacag
    43501 agacgttgtt gctgaccacc tgataaggtc aaggctgact tgtggagatc gtctttaacc
    43561 tgatcccaga gggcagcctg acgaagggag gtttctacga tttcatctag gacttgctta
    43621 tccttaactc cagcacgttc atgcgcaaag gtaatattac ggtaaattga cttagcaaat
    43681 ggattggggc gttgaaaaac cattccaatg tgtttacgca tttcataaac gttgatttct
    43741 ggacggttga catcaattcc acgatagaga atctgcccag ttactttagc aatatcaata
    43801 gtatcattca tgcgattgag actgcgtaag taggtagatt tccccgatcc cgacgggcca
    43861 atcaaagctg taattttatt tctttcaaat tgcatatcaa tccccttaat ggattcattt
    43921 ttaccatagt aaacatggac atccttagta gaaagggcta ctttttcttc aggaaaggta
    43981 aggatatgct tctcatccca gttatatgtt gacatggctt ctcctttagg cagcggttaa
    44041 tttcttgtgt agatagcttc cgaacttacg agctccaaag ttaaaaatca ggataaagat
    44101 caggagcaca gcggcagaac ctgctgatac aatggttcca tctggaatag tgccttcact
    44161 attgactttc cagatatgga cagccaaggt ttctgcttga cggaagatag agatggggct
    44221 agtcacactg aggatattcc agttagacca gtcaagagct ggcgccgatt gccctgctgt
    44281 atagatcaga gctgcagctt cgccaaagat acgaccagat gccaagacga cacccgttac
    44341 aatacctgga agcgcttctg gaataacaac atgaaccact gtctcccagc gagaaatccc
    44401 aagagccaga ccagcctcac gttgggtatg gtgaacgtgt ttcaaactat cctctacatt
    44461 acgcgtcatc tgaggcaagt taaagactgt caaggccaag gcacctgaaa tgattgaaaa
    44521 tccatactca aactggacta caaagatcaa gtaaccaaag agacccacca ccactgatgg
    44581 taaagaggac aagatttcaa tacaagtccg cacaaagttg gtaacaggac cttttttagc
    44641 atattcagcc aagtaaatcc cagctcccat agaaagaggt acagaaataa tcaaggtaat
    44701 gaccaatagg aaaaaggaat tgtaaagctg aatgccaatc ccaccacctg cttgaaaagc
    44761 agaagacctt ccagtcaaga aagaccaaga gatatggggc aagccccgaa ccaagatata
    44821 gagaatcaag gaagccaaga ttgtcacaat gatgctagca atcgtataga ggacagctgt
    44881 tgcaagttta tctaatttct tagcgcgcat aatttttctt tcctctttct ttcgtaatca
    44941 atttaatcac actgttaaaa actaagctca tcaagagcag taccaaggcc agtgaccaga
    45001 gaacattatt atttacagtt cccatgacag tgttcccaat tcccatagtt aatatagaag
    45061 ttaaagttgc agctggtgtg gtcaaggaag ttgggataac agctgagttt ccgacaacca
    45121 tctggatagc tagagcctca ccaaaggcac gcgccatccc aaagaccact gcagtgaaaa
    45181 taccagaacg ggccgccttc aagatcacac gccagatagt ctgccagcga gtggctccca
    45241 tagcgaaact ggcttcacga taataacgag gaaccgcacg caagctatcc gttgtcataa
    45301 aggttacggt cggcaaaatc atgacaaaga ggacggaaat ccctgacaaa atcccaaaac
    45361 cagtcccacc aaagacactg cgaacaaagg gaacgacgac ttgcaagcca ataaatccgt
    45421 acactactga aggaatccca accaggagtt caatagctgg ttgcaaaatc ttcgcccctt
    45481 ttggtgatac ttcggtcata aaaactgctg caccaatagc aaagggtgtt gcgataaggg
    45541 ctgagagaat ggtaacgata aaggaaccca aaatcatagg aagggcacca aattctttac
    45601 tagaaggatt ccaagttcct cccaaaagaa agtcaaagat attcacacca ttgacaaaga
    45661 aggtcgacaa gcctttttgc gctacgaaaa ccaaaatcat ggccacaagg atgactatca
    45721 aagaaagaca ggcaaaggtc aaaccttttc ctaatttctc cagacgagaa ttctttgatg
    45781 gaagcaacat tttcttagct aattcttctt gattcattat tgtctccctt ccaacactgt
    45841 cacagttccg gcagcatctt tttcaacctt catttcctta atcggaatat acttcaatcc
    45901 tttgacaatc ccttcttggg tctcatccga gagaacaaaa ttgagaaatt ctgcagctaa
    45961 ctcattgggc tgccccaatg tatacatatg ctcataagac cacaagggcc aattattact
    46021 acttatattt tctggactta agtcatagcc attcaacttc atgcttttga ccgaatcatc
    46081 tatataggta agagataaat aagagatagc tcctggactt tttgatacga ttgattttac
    46141 cgctccattt gaatcctgct cctgactttg catggcagac tgaccttcca taatgacagt
    46201 atcaaaggta gcacgagagc cagagccggc tgcccgattg ataacagaga tgggtaagtc
    46261 cttaccacca acctctttcc aattggttac ctcacctatg aagatttgac gaagttgctc
    46321 tgtcgttagg ttatcaacat caacctcctt attgacaatc agagccaagc cagctaccgc
    46381 gaccttgtgg tcaacaagag cagaagcatc aattccgtct ttttcctcag caaatacatc
    46441 tgagtttcct atatcaactg ccccagactg aacctgggac aagcctgtac cagaacctcc
    46501 cccttggaca ttgaccgttt ttccaacatg gatcgtgcca aattcatctg ccgctacttc
    46561 aaccaagggt tgcaaggcag ttgagccaac agccgttatg gattctccac gatcaatcca
    46621 gctagcacag cctactaaac aagccgtcag ccaaaaagcg ataagagaca gagcaagctt
    46681 ttttcttttt ttcactgttt ttctcctcga aaataattat gaatactgtg aattttttaa
    46741 gtagttcttt atgagttgac gcatgaattc ttaccaaatt tctgcgcaat tgattattta
    46801 tataatatag gctatattac tctttcctaa cctccttttt tcatatgtgg ataaaatctc
    46861 ttgtctatcc cttcccccat tgtcacccat tatagtcatt tcgtgtctct ttttcccctt
    46921 tttaatgcaa gggaaattac tcttcttaga tgataatcca aaagctagaa aggtatctca
    46981 aacctctcta ctctcccaga ctagtttaca actaaaagaa aaagattcta ttttatgaga
    47041 aatctagttt acaagcggta agaacgctaa taactaaact tcttgtactc tttgaaaatc
    47101 tcttcaaacc aatgttttga gctatctatg gctagcttcc tagtttgctc tttgattttc
    47161 attgagtagt aaaactacat gtaatggcaa tcaagatatc aagaatcatc ctactaaaaa
    47221 aatccatact ttcactataa catagaataa gatatttgac tagcattttc atttgaatct
    47281 gaggcctttt ggaaaataat ttttcaaaac atttccagta acctttgcaa agcccaagcc
    47341 attgccttta accaaaactt ggtaccaacc atttggcaga ctttctgcca gctgaacggt
    47401 ttctccagcc gcatacttga caaacgcttc ttggccaatt tcaaccgact gttcgacctg
    47461 actcggtttc aaggctaaac caagagcgaa actgggctca aagcgtttct tcttaaaagt
    47521 acccagatgc agtccattgc gagcaatctt gagcttccct aaatctggca aaagttctgg
    47581 caagagataa agctggtctc caaaaatctg caagataccc ggtagattga ccttcaaatg
    47641 gttttgggca aattcctgcc acaaggcaac ttgttcacgg ctgaggttac tcttacttgc
    47701 cttaaattta ggagctggat tgttaccctt aaactgtaga tgggcaacaa actgaccctc
    47761 tcccttaaac tgatgagggt acatccgagc cgtttctggc aggtcaatac cagctaccat
    47821 tccattgata tgctctactg gcaacaagtc aaaatcatac tcttccagca accaattgac
    47881 aatctcttcg ttttcctcgg gtgcccaggt acaggtcgaa taaaccagac gaccaccttc
    47941 agctaacatg gtcactgcat cctccagaat ttctctttgc aagctagcac attgactcgg
    48001 ataatctaag ctccaatagt ccatagcatc aggttgctta cgaaacattc cttcaccaga
    48061 gcaaggggca tcaagaacga ttaagtcaaa atagccttta aagaccttga ccaagcggtc
    48121 ggcagattca ttggtcacca cgacatttgt cgctccaaaa cgctccatgt tttcaaccaa
    48181 aatcttagcc cgtttgcttg aaatttcatt ggaaacaagt agcccctccc ctgctagata
    48241 ggctgccagt tgagttgatt tgccccccgg tgcagcagcc aagtccaaga ccttcatacc
    48301 aggactgggt tgggctactt gagccaccat ttgagcagca ggttcttgcg aataaactaa
    48361 acctgtagca tgctcaggcg atttccctga aaccttccca tagtggcccc aaggggtttg
    48421 agtaatggca tcagaaaagg aaagttgctc ttcttttaag ggattgaccc gaaaggccga
    48481 aaccgcttcc tcctcaaaag aggcaagaaa atctcttgcc tcatctccta gtatctcttt
    48541 atatttttca acaaatcctt ctggaaattt catttaagtt cttttccttt cgtaaatata
    48601 ggactgaatt tcctcctgca tctcaagagg caccatcatg accggctgtc tggtttgaaa
    48661 atcaggagct tcaccaaaaa gggtcacaac ccgatagccc agactttccc ctaaaatact
    48721 agctgcggca taatcccatg gttgcagata agtgagatag gtcaacaaac gccctgacaa
    48781 aatcttggca aaactaatgg ccgcacttcc atagacacga acaccaagaa ccgatcggct
    48841 caaatcagcc agcccccatt cattggtttc cagcatacca ctattccctg caatgagaaa
    48901 atctccaagt ggtttagttt taaaaggagc taggggccta tcatttagac aaactggaaa
    48961 ttccccacca ccgtggtaac aatccccttt gaccacatca taaatcagac caaactgtcc
    49021 ctgaccattt tcaaaataag ccatcataac agcaaaatct tcctgctggg ctacaaaatt
    49081 attggtacca tcaatgggat caatgaccca aaccttgccc tcttgaaccg aggctcgcag
    49141 acaaccttct tcagcacaaa tcttatcctc aggataacgg gacaaaatct caccaaccaa
    49201 gagttcctga acttctttgt ccagtctggt caccaaatct gttggagagg acttggtttc
    49261 aacacgcaag tcttcctgca tatggtcaag aatgtactga cctgctttct taacaagctc
    49321 tttagcaaat tcaaatttac tttccaagag aaatctttcc ttcccctttt tctttggcag
    49381 cctgaactgc tcggtaaagt gaatagccac taaccgtttc aaattctcgt cccaaacgtt
    49441 tctcttcgct cttgcttggc acgaccgctt tgaatccctt ataggagtcc agtaactttt
    49501 tagcctctac tttgccttca taggcagctt caacatcatt aaaaaaagaa agcactgaag
    49561 caagttcttc agtgctccac gacaaatcta gtgggtaact atactgtttg ttcattaact
    49621 aataccagct ctcattcttg cttcttttag ttcttgctta cgataactac gagggagaaa
    49681 agcacgaatc tcatcttcat taaaaccgat ttgcatacgc ttggcatcaa taataattgg
    49741 acgacgcaaa agactaggat actgctcaat caaatgaagc aattccgata ccgaaatact
    49801 ctctacatca atattcaatt tttgaaaaat ttttgaacga gttgaaatga tgtcatcagt
    49861 accattttcg gtcaaggaaa ggatgtgttg caattctttt cttgttaaag gactggtcat
    49921 aatattgtgt tccacaaagg gaaccttatg tttttctaac caggccttag ccttacgaca
    49981 tgatgtacag ctcggtgata gaaatagtgt aatcatgctt ttctcttctt atctatactt
    50041 tgctacttct attatacaaa aaaataaggc gcttgactag ggatttttag aaaaaaagcc
    50101 tattttttca ggaaaaatag gctgtttgcg aacgattgac acaattggat ttggttaatt
    50161 cactcttaac gatggtttta aacgatatat atatttatat atgtaaatta aaaacatctt
    50221 tcctttcact tcctacgact tttcagacac agatagccaa agaagttttc atagagggca
    50281 aaaaagagga ggaaggcatg aagaaagaag gtctctggca aaatcataat aacaggatcc
    50341 ttggctggat caaaaagcca ggtatcatct cccacaaaga gaatttgatg gaaaagagta
    50401 aagaattggt caaaaccaat caaaactccc ccaagtccaa tcattacagg taaaactact
    50461 agagccagga gactttttcg ataaagagac aaaaagtcct ttttcacaat cctattgaca
    50521 aagacataga aacttggcag tgtcactaga gctactagct gaaccaaatg aaagagattc
    50581 ttgaccactg cgaaatggtg cagaccagct gctgacgaac gaaaatcagg catctgtaag
    50641 acctgactaa aaggattggt cagataattc atcaagatat gaaaattgta ttgaatggtt
    50701 tctggtttta gatagactcg attcgttaag tttagccact gaatctccat aggatagaaa
    50761 atccaagcca gataaatggt cagaaggatg gagagggaga ggagaaagag catagagccc
    50821 caaaagatca atttagtttt catcaaaatc ccactccgca aggctagaaa ccacatgtgt
    50881 cggtgcgatt ggcaggccag ctacttcttc tgccttagta aaacctgtcg tcaccaagag
    50941 cgttggaatg ccattgtcaa tcccagcccg aatatcagtc aaataattgt ccccaaccat
    51001 gattaactct tcacgttcca aacctaagtg ctcaaccgcc ttgtccataa tgatggcatt
    51061 tggttttccg atataaaccg gcttcactcg tgtcgctact tcaagcagcg taatcagtga
    51121 gccagcacct ggcaaaagac cgcgttccgt cgggatgttg aggtcaggat tggttccgat
    51181 aaaatgggca cccttttgaa tagcaagagt tgctgtggca aatttttcat agtcgacttg
    51241 ccaatccaga ccaactacca cgtaggcagg tttttccttg tcttccacat aaccagccgc
    51301 cttgatggct tccttgagtc ctgcttctcc gacgacatag acggtctttt caagccccaa
    51361 atcattcata tagtcgatgg ttgccaaagt cgctgtgtag acagtcgata ggggcgtatc
    51421 gatattaaaa ttctgagcca acatctcctt aacactctct ggagtgcggg ttgtattgtt
    51481 ggttacaaag agatagggaa tgtcccgctt ttgcaattca tgaacaaaag tctctccagc
    51541 agggattcgg tctttcccct tataaatggt tccgtctaaa tcaattaaat agcctttata
    51601 tttcatctat ttctccctaa gcctttttta tttcttgcca agtaatgatt gcttgggcat
    51661 tgataacccc atcacttgta atttcatgct tgctttccag tccagtccgt tcaacagccg
    51721 atgtaatcac cccacctggt cgaacttcct tgacatactt gaggttgatt ttcttgggaa
    51781 tatagtgggt caaaaaatcc gctcccatga cctcaaaaat ccagtccaag tatttactgt
    51841 tattgacatg accattcata tccaagtcgt aaaaacgaac atggtaatcc ttgctgatcg
    51901 gttcttccaa ggactcatac ttcggtccac ggataagttt tttatcaaaa tcagactggt
    51961 aaggagccac aatctcaggt tcaacaacat ggacttttcg actgtcgcgg tccatgagaa
    52021 caaaggtcgc catcatgtgg atgagctcct gctccgcttc attataaata gtaaagcgac
    52081 ggtagcaaaa aagtcgattg tagctcaagg cttccgtttc gatggtaatt tcttccgcaa
    52141 aacgaggcaa acgaaccacc tcaatatcat attctacgat aatccagacc agattatatt
    52201 cttccaaaat ggccttatca ctaactccca gttcaatcga ctgcatccct gaaacttgca
    52261 gtgacagcaa aatcacatct ggaagtttga tatgaccgtt catatcagcc atatcaaaag
    52321 gaattttcat tttcatttga taagttaagc ccatgatcct actccaaaat aaatcgttct
    52381 gctacagtat ctcccaaaaa gagacctctc tttgtcatgc gaacgtggtc accctcaatc
    52441 tgcatgaggc cttgttgaac caaatctctg acaatttctc cataaagtcc agcaaaagac
    52501 tgtccaaatt tttcctcaaa tcgcgccatg gaaaccccgg atttcttgcg gagtcccaag
    52561 aacatttctt cttccatttg ctccttttga ctcaggtgat cttctgtaat acaagcattg
    52621 ccttcctcaa ccgcactgag ataatgacga atgggaccat gatttttata gcgtactcca
    52681 ttgacataac cagatgcccc tgcaccaata ccatagtatt cagcattgtc ccagtacatg
    52741 agattatgac gactttcaaa accgggtttg gagaaattag aaatctcata atgctcaaaa
    52801 cccgctcgct ccagctctgc aatgatgtac tcaaacatct ccgcttctag ttcctcctta
    52861 ggcagaggca atttcccacg tcgcatccgg ttcataaaga ccgtatggtt ttctaaaatc
    52921 aaactataca aactcatgtg gggaatatcc aatccaatgg ctttagccac attttccttt
    52981 acttgctcca tggtctgacc aggcagagca taaatcaaat caatggagat attgtcaaaa
    53041 ccagccagtt tcaggcgatc gatattttca taaatatcct tctccaaatg actgcgccca
    53101 atctttttca acatcttatc atcaaaggtc tggacaccta gcgaaacacg attgacagcc
    53161 gaatttttca aaacagctat cttatccgca tccaaatcgc ctggattggc ttcaatggtc
    53221 aactcttcta agacagacaa gtccaagttt ttagtcaagc cattcagtaa aacctccagt
    53281 tgcggagccg acagggctgt cggtgttcca ccaccgatat aaagggttga caacttttca
    53341 atatcataag aacgaaactc ttccagcaga tgctctaaat agctgtcgac tggctgattt
    53401 ttgatgaaga cctttgaaaa atcacaataa taacaaatct gggtacaaaa tgggatgtgc
    53461 acataggctg acgttggttt tttctgcata gtaattatta taccacaaag actagattcc
    53521 agataaaaat caccatcccc agatacatag tccgttcgga gatggtgatg gtttattctt
    53581 ctgttatatc aatcacaatc tcttctgagt catcaagagc ttcggctttt tcttgccatt
    53641 gttccttgag attatttaat tgattttttg atgcttctgt cgcttgaaaa gcataggatt
    53701 tagcttgagc aagtatactg tccacagtga tttcacctga ctcaacctgt tcttttgttt
    53761 tcagaacaaa atctgtagcc tgctccttaa cttctgtcag tttttcacag acttgctcct
    53821 tggcatactc cggatcttct ctcaaatcat ctagaaaatc ttgagcctga ctgcaaactt
    53881 gtttgccctt atcacttgtt aaaaacaagg caagagctgc acctgaaacg gttcctaaaa
    53941 ggattgagga taatttaccc ataaggattc tcctttttta ttttttgaaa aatttacttg
    54001 caagacgaag agctgacaga cttgcaccag tcttgagtgt ttttgaacca gctgatgaag
    54061 ctttcttgct caagacacgc gcatggtcat tgaggtctga aacagataga gataaatctg
    54121 caacagcact gaagagtgga tcaatcgtag ccaccttgac attgatatca tctgccaaga
    54181 cattgacctt agccaacaac tcattggtgt gatgcaaggt cacatccaca tctgaagtca
    54241 aggttttaat cgtcttttct gtttcatcga tgacacgacc aagcttttgt acagtaatga
    54301 tcagatagac caaaaagaca atcaaagcta gggcaacaag aatatatgca acttctaaca
    54361 tttagttttc ctcctctgta atatagtaag gggccttctt tcgattttga taaataacga
    54421 tcattatacc gagaccgata aggacaactg acagccattg ggacactcga aagccgaaga
    54481 acatgagact atctgttcgc ataccttcga taaccatacg accgaaacca taccaaatca
    54541 agtaaaaggc cgtgatatga cctcgtctga gactcttcca tttccgtcta aaaatcagaa
    54601 tcaaggcaaa gccaagcaga ttccatagag actcataaag gaaagtcggt tgacggtagc
    54661 tcccctcaat atacatctgg tcacggataa agccaggtag ataatccaga ttatccactg
    54721 ttgcaccata agcttcttgg ttaaagaaat taccccaacg ccccaaactt tgagcaatca
    54781 taacgctagg cgccgcaata tctagaaaat cccaagtatt gatgagttta cggtcagcaa
    54841 agatatagag cacaagagcc ccagttatca aaccaccgta aatggccaaa ccaccattcc
    54901 aaatggcaaa aatctctcct aaattctgac tatagtaatc aaatcggaaa ataacatagt
    54961 agagacgagc tcctaaaata gccaagggaa aggctactaa gataaaatct aaaatatcgt
    55021 ctggtatgat cttctttcta ggtgcttctt tcatggtcaa ataaaccgca agaatcaagc
    55081 ctgtcacaat acataaggca taccaacgaa tggctagggg tcctagttga atagcaattg
    55141 gatcaagcat tttgcacctc atttcgagcg attagacttg tcagtcgttc gtcgaacaaa
    55201 cgggtcgcat caaagcccat ttccttggca cgataattca tggcagctgc ctcaatcaca
    55261 acagagatat tacgacctgt tttaactgga atacgaatac gaggaatggc tacgccagaa
    55321 acttcaagtt cctctgcatt atttccaaga cgatcaaagg tcttatgcgt atcgtaattt
    55381 tccaaataga cagcaagctg aacctgtgaa gaatccttga cagcactcgc accgtagaga
    55441 ctcataacat cgataatacc aaccccacga atttcaatca agtgtttcaa aatttcagct
    55501 ggttcacccc agagagtaat ctcatccttg gcaaagatat cgacacggtc atcggctacc
    55561 aaacggtgac cacgtttgac aagctcaaga cctgtctcgc tcttaccaat tccactatct
    55621 ccctgaatca agacgcccat cccataaata tccatcaaga caccgtgcac actggtacgt
    55681 tctgccaaac gagaatccag atagctagat aactctccag ataaacgact ggtagctgca
    55741 cggctggtta aaatagcaat cttacattct ctagcagcct ttaacatctc ctctggaacc
    55801 accaaaccac gggcaacaat gactgctggt gtctcaggta gaaacatttt tttcaaaact
    55861 tcataacggc tgttggaagg catgctgatc agataagacc actccttcat ccccaaaagt
    55921 tgaatccgct ctggtgtata gtagtcaaaa tagcctgtca tttcaagacc aggtcgcgta
    55981 atatccgctg tattgatttc cttttcaagc aattctggtt caccatagac aatgtctagt
    56041 ctaagctttt caatcacttc ttttactaaa accgacatca tttcctcctt caaatgagtt
    56101 cttctctcta ttatatcaaa ttgtaggagg aagtttcaga tttttgcagg ctttggagta
    56161 tttatttaaa agaaaaagga ctagatttct ctagcctttc atttcaatta gaatttttta
    56221 cgtttacgag ctacttctga tttacgttta cgttttacag aaggtttttc atagaattca
    56281 cgtttgcgtg tttcttgaag agtaccagct ttagtaaccg cacgtttgaa acggcgaagt
    56341 gcgtcgtcaa gagattcatt cttacgtact actgttttag acattttttt cactcccttc
    56401 aagttcaaga tctattctat tttacacgta aaaggaataa ttgtcaagag gaaactaagt
    56461 tttttattct tcataatgat taataatata gttcaccatc tcctccatat ctgcttcaga
    56521 taaaggtaat tcccagtttg ttgtttccat tttaagaaaa gcatcactga ctttagttat
    56581 tgtatagcaa tctttaaaaa ttggaatttt tttagattgt tcaaataaga tgcctattct
    56641 atcatataag acgtgaagtt ctttactatt tggatcaata tcaaaagact gtaaagagat
    56701 taagatgtca tttcctttat atgacaaatc aatccacatg tgatttgata aatcatatgg
    56761 cctagataat ctactacccg aggtgtactt tttatttcct ccgcctcctg aatattgatt
    56821 tcttgtggta tatggtttat cttttgactt agtaaaaaga aaattcccct ccttatcttt
    56881 cttttttgta atgaagccta ttatactttt tctttcttcc gttctagcac tcttatatgc
    56941 ttcttttatt tttaaaaatt cttctttatt catgtgtcct cctaaagtta agttgaagtt
    57001 ttatatgtct aaaaccactc actccaaaga gcaagcggtt cttatacttt ttatttttcg
    57061 agtaagctaa gcgcttcagc atctgcgatg atggttacat cagggtgatt ttggaggcta
    57121 cttgcaggta ggttctcagt cactgggcca gatactgttc cggcaatggc ttctgctttc
    57181 gactcaccgt aagcaaaaag aataatagac ttggcatcca aaatgttttt aatccccatt
    57241 gaaatagctt gggttgggac gtcttcaatc ttggcaaaga agcgtgcatt ggcttcgata
    57301 gtagactggt caagttctac tacatgcgtt tgactgtcaa atggagtacc aggctcatta
    57361 aagccgatat gcccattgcg accgattccc aagatttgga ggtcaactgg atggtcagcc
    57421 aaaatttggt tgtagcgttc aacttcagct tcagcattgt ccttaacacc acgaggcaag
    57481 aaactttctt taaatggttt ttggttgaac aagttttctt gcatgaagta acgataagac
    57541 tgtggattgt ccccatcaag gcccacatac tcatcaaggt tgacactggt tagatttgaa
    57601 aaatcaaggt cactctcaac aatttccttg taaaattcaa gtgggctact tcctgtcgca
    57661 agtcctagag tttgagctcc attagccaat ttttccttca aaatctcaaa agcaactttt
    57721 ccaccttgaa cttggttttc aactttaata actttcatct tttcatcctc catttctgtc
    57781 tatatttatt atatggtata gaccaatttt tgtcaagtga aaacgattta atttctaaaa
    57841 aaagagcgtc caaacttgaa acgtgttata atggatagga ttagaactta gaaagaatga
    57901 acaaatatat gaatacagct gattttgatt tccacttgcc agaggaattg attgcccaaa
    57961 cgccccttga aaaacgtgat gcctccaaac tcctcatcgt caaccgtgag acaggagaaa
    58021 tgcaagataa acatttccac tctattattg atatgctgga acctggtgat gcccttgtca
    58081 tgaacgacac ccgagttctc cctgcccgcc tctatggtca aaaagtggag acaggaggtc
    58141 atgtggaact tctcctcctt aagaacacta gtggagacga gtgggaagtt ctggctaaac
    58201 ctgccaaacg cctcaaggtc ggtactcgta tcagctttgg tgatggccgc ctcagcgctg
    58261 tcgttacaga agaattgacc cacgggggac gcattgtccg ctttgaatac caaggaattt
    58321 tcctagaagt cttggaaagt ctgggagaaa tgcctctgcc accttatatc cacgaaaaat
    58381 tagatgaccg tgaacgttat caaaccgtct acgccaagga aagcggctct gctgcagcac
    58441 cgactgctgg tcttcacttc accaaagaac tgctggcaga aatccaagct aagggtgttc
    58501 atctagtcta tctgactctc catgtcggac tcggaacctt tagacctgtt tctgtggata
    58561 atctggacga acacgaaatg cactcagagt tctatcaact ttctgaggaa gctgctgcca
    58621 cccttcgctc tgtcaaagaa aatggtggtc gcgtcatcgc tgtcggaacc acttctatcc
    58681 gcaccttgga aactattggt tccaagtttg atgggcaaat ccaagcagat tctggttgga
    58741 ccaatatctt tatcaaacct gggtatgagt ggaaggtcgt ggatgccttc tcaaccaact
    58801 tccatctgcc aaaatcaact ctggtcatgt tggtttctgc ctttgcaggc cgtgaattag
    58861 tcttagatgc ctaccaccat gccatccaag aacactaccg cttcttcagt tttggtgacg
    58921 ccatgtttat ttattgagaa agaatttctc taattcttct aataccaata aatcgctaag
    58981 atattatttc aaagaacatc tacaattgaa actctagcta gctgtagaag acgcctagta
    59041 cattgaaatt aaaatgcttc cccctagctt cgaaaatatt gccatagatt gcgttgactc
    59101 tccaaattga ttcatctata ttttatttca gcttcctata ttttcttcgc tgtttgtaaa
    59161 tcaaaatgca agacacatga gtagcaccat atttgttact cttatctgtc ctctcaagag
    59221 actattatga gttatttcag aatcattcac tactttgacc ctgactctcc ttagtctcaa
    59281 aatcaaagac ttatactctt caaaaatctc ttcaaaccgc gtcaacgtcg ccttggatta
    59341 tatatgtgac tgacttcgtc agtcttatct acaacctcaa agcagtgctt tgagcaacct
    59401 gcgactagtt ttctagtttg ctctttgatt ttcattgagt attaaacaaa aagtgaacaa
    59461 atctgaattc taatgtacag aagactaggc ttgttcactt ttttatagtc gctataagat
    59521 gaccttatct atagcttttt atatataatt atatattcag acatactatt atcaattttg
    59581 tcgcagggag gaatctgtta acgcacccat tcaccattat cattgactct atagccatct
    59641 atacttgtat tgaccgctaa ctcacccgat gtatttacat aataccattt accaccaact
    59701 tggaaccatt gattgacttt catagaaccg ttgctgttga ggtagtacca tgaaccatta
    59761 acttgtaccc aacctgttgc catggaacca tcagtattat aaaaatacca cataccattt
    59821 tcttgtttcc agcctgttgt tggagcaact gctttagctg gttctactgc tacatctgtt
    59881 ccttggttag atgtaacaga tacaggatac gaaggaatag atgattgctc aggaacaaca
    59941 actttttcag gttctctcgt ccctctcctt atacgtcttt ttaccatctc tttagtaatt
    60001 tgacgagaag tagtttcttc aattgttcca tcacgttcat ctacagtata gattgtagta
    60061 agagtaattt accaatttct cctacttctt ctacttcttg acttttatca agagttgggc
    60121 catcgagata ttctgtttcg attgaaattt cttggacaag aacttggggc ttggttcctt
    60181 ttttaacaac tcttgtttga gagtcttctt tttgacttaa agtactctca gttacttgtc
    60241 cactctttcc atctacatca taagttatcg ttgtaactgt tttcccattc tttcctagag
    60301 taatctcttg ctcctgtcct gcagaaaggt cattgtctgc ttcatattta gtagcaaatg
    60361 gaacaagaac ttcttcaacc ttgcttttag ctggaacttt gataactgta tccgtggctt
    60421 cttttctatc aacagtaacc ttttcggtaa catgaccagt ctctggatta acatcgtagg
    60481 tccttgtcgt ggttacatag ccatcctctc cgtcaattgt aacatgattt tcactacggt
    60541 cttttgtttc atctttttca aaacgaattc gcgtacttga aattttcttg gttactacct
    60601 taggtttagt cgctactttt acaataatat ccccattgtc agcgtcatca tactctattc
    60661 cctcttcttt atctctagta tcatctctga catattgaat cccatcagca gcatgagcaa
    60721 aacttgtatt cagattcctc ctaaaaataa agttagcccg attaccgcag aaccaaaaat
    60781 ctttccgagt ttacgtattg catagcgctt attagtatta gattttgcca ttacatccta
    60841 cttctagtat agcatctttt ctatcaaacg ttaaacaata tactttatat ataaaataga
    60901 cttagaatga tatatttact attgaactaa cactttaact atatcgtaat caatctcata
    60961 tataaaggat tgcagacatc tgatctaaat acatgctaat atatttagat acaaacattc
    61021 caacttgata attttcactc atctttcatc attccttaca caacgatgca gtataaatag
    61081 aatagttttc tcatcagaat gagactattt taatattaga taatttgata gaaaaacata
    61141 aataaaattg gttgaattta attccctaac tcgatagagg attctatttt aaatttaaca
    61201 acagctagga ttacactata aaaagtacat taccacctgt tcggctggag aacctagtcg
    61261 attagctccc tcttagttac aagcttcaag cgatttttta actaatacta aaccagatta
    61321 aagaaggaac tagagcatct gtcttgtaat aatcaatatg ctattttaaa attgcaaata
    61381 aacttggaat gctaattatt atatttacaa taaatagttg acttcgatag aaacagaaaa
    61441 tagaattcaa cattcttccc tacttatacc ataataaata agatccgcaa gatagccttt
    61501 tctctctaca ccattaacaa tggtttgtag ataggacatt ccagcctttt ccatgacacg
    61561 acctgaagct gggttgagac tggcataacg tgctctgacc ttttgaaaac ctgcttgagt
    61621 aaaacaaaag tccaagacag ctttcaaggc ctctgtcatc ataccatgtc cccagtaaac
    61681 cttgcctagc acatagccga tttcacagct taaatcagcc tcgtctatct taacgatgct
    61741 gatatctcct atcacttgct ctgggttttc ttttagacaa atggcccatt tgtaatagtt
    61801 gagattagta taggaagcaa cccaattgcg aatcgagttt cgagtgattt cgacatcagg
    61861 atggggatcc caggtaacat aggtcaaatt ctcagcggat gaagcccaat tttgaaacat
    61921 agcttctgca tcactctcca caaatcttct taaaatcaaa cgttctgtct gtaatatttg
    61981 cgtaccgata gatttcatga tgctacctca cttccttatt tctatgctcg tagtaaaaag
    62041 gctcaactca gtaacagcta gaaaacgagt ttgtcttcta atttcttgac gcagtcgctg
    62101 cctggtttga aatgcgctct agcaagcttt ttcaaaccta gtcatcgttg caggggtaag
    62161 acgatgaaat cgaactcttc gagttaccga atctgcctca ttttcttatt tctaaactcg
    62221 gggttcaaga tcccccagac cttctctcac tttcttattt caagatgaga ggctgaaaac
    62281 ctccaatgga ggtttttact cccaaaagtc atcaaatacg gtgatgggta agtggcgttt
    62341 gtgttggcct ttgtgccacc agttttcaat ggtcgcttga gcttctgggc tgattgtttt
    62401 gccttctagg tagtcgtcaa tctctgcgta ggtgactcca agtgcgactt cgtcagctag
    62461 gcctggttta tcttcttcta ggtctgctgt tgggattttt tcataaaggg ctggctctgc
    62521 gccaagtttc tgcaagagct gttttccttg gcgtttattg aggcggtaaa gagggagaat
    62581 atccgcaccg ccgtcaccaa acttggtaaa gaaacctgtg atattttccg cggcgtggtc
    62641 tgttccaatg accgctccgc tatgggaacc agcaagggca tactgagcaa tcatacggca
    62701 acgtgccttg atattcccct tgttgaagtc tgaaacagga ctacctgtcg cttcaactgc
    62761 agctgtcata gcatcagctg actccttgat attcacaacc aagctgacat ctggctggat
    62821 gaaggctagg gctttttgag catctgcttc atcagcttgc actccgtatg gcaggcggac
    62881 agcgataaat ttgtagctgt cgtctcccgt ttcagctcgc agttcttcta tagctaattg
    62941 cgccaaacgt cctgccaagg ttgagtcttg tcccccagaa atccctagta caaagttttt
    63001 taggaaggga tgttttttca gatatctttt taagaaatca atagaacgac ggatttcttc
    63061 ctgggcatca atcactggtt tgacacccag ctcttggata atcgtttctt gcaaactcat
    63121 tcttcttctc cttcaccaag ggcttccttg cgcatcttat caatcaagtc catcttatct
    63181 tgccatacat cacgtgccaa atccactgga tagtgctgcg gattgagcac acgcttatac
    63241 tcatcccaca acttgtcaaa ttctttacgg gcataatcct gaatgtcagt caaactaggc
    63301 aagttgtaaa ctaatattcc ttctttgaag atatccacca agagaggaac ggcatcaaaa
    63361 ttacgaaccg tcttcttgat gtatgtatag gtcggatgga acatcttgat ttctgtcatg
    63421 tcgctaatat ccacaccatc ataagtgatg tagtcacctt ctgacttgcc tttttcacga
    63481 ctggtaatgc gccacacctg cttcttacct ggcgtcgaca ctttttccgc attattagac
    63541 agcttaatcg tattgcgcat ctgaccagtt tcatcttcaa ttgcaacaat cttgtaaacc
    63601 gccccaagag ccggctggtc ataggctgta atcagcttgg tacccacacc ccagacatca
    63661 atcttggcct tttgcatctt gaggttaagg atggtatttt catctagatc attagaagca
    63721 taaatcttag cctctgtaaa tccagcctcg tccagttgct gacggacttt cttagaaatg
    63781 taagcaatat ccccagagtc aatccgcaca cccataaagt taatctgatc acccagttca
    63841 cgcgccacct gaatggcagc tggtacaccg atgcgaaggg tatcataggt atccacaaga
    63901 aagacacaat ttttgtgggt cgcagcgtaa gccttgaaag cctcatagtc attgccataa
    63961 acctgcacca aggcatgggc atgggttccc aaaacaggaa tgtcaaagag tttacccgca
    64021 cgcacgttgc tggttccatt ggcgccacca atcaccgctg cacgtgttcc ccagatggcc
    64081 gcatccattt cttgagcccg acgtgtccca aactccatca agggttcatc ttcgataacc
    64141 gaacgaatac gagctgcctt cgtcgccacc aaggtctggt agttgacgat gttcaaaaga
    64201 gccgtttcga ccaactgaca ttgggctaga ggtccttcca cctgcacaat cggttcatta
    64261 gcaaaaacca aatccccttc ttgggcagaa cgaacggtca actccaactt gaaattgcaa
    64321 aggtaatcca agaacgcccc atgataacca agcgactcca aataggctat atcactatct
    64381 gaaaaacgca agtcttcaag atagttcaca attctttcca aacctgcaaa aaccgcatag
    64441 ccgttcttaa aaggctgttg gcggaaatac acctcaaaga ccgccttctt attgtgaatc
    64501 ccttggtcaa agtaaacctg catcatgttg atctggtaca agtccgtgtg caatgtcaaa
    64561 ctatcatctg gatacatact tttcctactt ccttagctag aaacccatga aaattttcaa
    64621 gaactttcat gtattccaat aaattagtac tattatatca cattttagct ggattgagaa
    64681 aagagtaaca agctattctc cactctccaa ttcatccata tcttgttcaa attttttctg
    64741 agcccattcg ccatagctct taagaccaag attgccaata aagacccacg gaaggtaaat
    64801 gacataagta atgacccaag cagacaggta tttaaaattc aaaggattgt gctgataaat
    64861 ttctatgttg aattgataat tctgcaacat caaaagagcc gtaatagcca aggttaggaa
    64921 aaaacaaccc aaaatcgtaa aatgaaaacg actatagtag gtcactccca gataacgggc
    64981 gcgattgaaa aagtaaaatg tccctatgat gataacgatt agcagcatat tagaattaaa
    65041 aaggcttggt gctaatactg aaatgatata agataggagc gacaaagcaa tgcagatata
    65101 gaaactttca gatcccgctt tattgaacag ttgttcttct ctttcgtcta gtaattgata
    65161 ataataaaat ctatttttca tcttcttcct cccaaaatag ttggtctagg gttttcccta
    65221 aacatctgca aatagactgg cagagcgaga gactgggatt gtattttccc gcctctatca
    65281 aaccaatagt ctggcgtgtc accccgacag cctctgccag ttgaccttgt gttaaatcac
    65341 gctctacccg agctaatttt aattttaaat ttttagccac cttcgtcctc cttatagttt
    65401 taatactcat ctactcttaa aaaatccaaa accaacacaa gctatcagct atttattata
    65461 accccattaa tttgcactcc agtattatct tcagacgaaa atcagtattt taggttgttt
    65521 gaaataaatt tcctagttta ctcttttatt tttatttagt attagcttta gtagaatctt
    65581 ttaaacgagt ttttattgct tatatttctt gtttagttta gttggtttca tatcactatt
    65641 atataatgct tttggaaatg agcctagtat aagtcaaaaa cgtgttgaat agtgaaagca
    65701 ggagcatacc aagatgactg atttttttac tgtattttag gtatgcaaaa taatactaaa
    65761 tgaaactaaa atgaatactt cttgcttttc ttgagagtga aaaagtacaa taaaatgatt
    65821 gtagtgatta gcacaagata ctgactaata gacatcgtat ttgaaaccac aaatagaggt
    65881 aaagaataaa aaggaagaag ttcaattgct ttgataaaca aatcattact agtattcatc
    65941 ataatcgtat ttaatatatt agggataaag agtagtaaag ctactaaaat accaaatacc
    66001 aagccacttt tcaatttgta taaatagaaa atgtaagata atagaaaata aaacaggact
    66061 aacaaaattg tattgactac aatagctact ataaaatcta atcctaaatc acctggaata
    66121 cccaacttac ttactatgac tagtaacaca atgccattca aagcataaat aatggaaact
    66181 gagatggcat atagaaaatt agacaagacg taaatcatcc gattcttctg ttgattataa
    66241 aacaaactta ccgtattgtg ggaaaaatct ctactaataa ctcgattagc atgtataaca
    66301 gccattaaca taccgagcat agcataaaag tttgaaatat gcttaatacc aagcgatgtc
    66361 tcttgagtct ttagaataaa gaatgtaagc aatatcggcg gtataaacga gataagcaaa
    66421 ctgagatata ttacgcctga tgaatataaa tttcttatat tttccttaag aaaattcaat
    66481 ttatttaatt tcatgattat aaccttcctt tattttgaac gatttaagta aatatcttta
    66541 agcgtctctt ttttagtttc aaaatcaact actttaatag agttttcgtt aaaaaattta
    66601 aaaagctcac tactttgaat attcccagac atagtaattc tcagtccctc ttcctgaaca
    66661 atatccccaa attcttgttt ggtaatgaaa atgtctctat ctgtagctga tgaaaaagct
    66721 atctcaaaca agaaattatg actatctttt cctacttttt gaaatgtcaa aagcccgctc
    66781 tccaagaaaa gaaccctctc acaaatttct tcaatgtctt ctaatttatg actcgatatt
    66841 aaaattccca cgttttcatt taaagctaat ttttttagaa ccgctaaaac tatttgtgat
    66901 gattcaatat ctaaaccatt agtcggttca tctaaaatca atatatcagg tttcgtaacg
    66961 agagttagaa gcaaagctaa tttttgtttt gtacccaaag aataggtctt tactttttta
    67021 ttaatagact gagtcaaatc taactcttgg atcaaacttc taaatctttc ttgattgtag
    67081 tcaacaccat ataaatttga caaatatttt aaattctcta aacctgtttt agataaaaat
    67141 aattttggtt cttcgattaa atacccaata ttatcactgc ttataatatt acctgaagtc
    67201 ggttgattat tctgaacaag aattttcatc aacgtactct taccaactcc atttctccct
    67261 actagaccaa caatttcacc cttgttaagt gcaaaattta tatctttgag aatgattgaa
    67321 tgaccataat gcttacttac atttataact tacatttttt attcctccat taatattcat
    67381 ggtttgctct ttgattctta ttgagtttaa aaagttgcgc ctctttttaa caacattata
    67441 tcatatatct aacttaatgc aatatataaa tgtcattttg taaaatttta ttaacaaaaa
    67501 actctctaca acaaaataat agagagtttt ctgcttatta atttttttca aaatatctaa
    67561 acatcacttc tttgtttaat ttgataggct ttgataccta agctccgact ttatcactta
    67621 aaaaataaaa aaggacagct aatctcttgc gcatcaaggg atttcgccat tctttaatct
    67681 cgtttaagtg ttgtatatgg agctttgcat aattttttaa aactaaacaa ctacattaaa
    67741 cacgaactgt gacgctggtt ccatcttcct tataaagatt gatgagtcct tcttttaatg
    67801 cacgaaccat gtctcctgat tgaacgggtt gaggcacctt aatagtcaat agttccattg
    67861 gatttggagc gcggtcgatt ttattgcctt tggcatcatg caaatcttca atataggttt
    67921 caaaatgacg gaaacctgga ccataaaact caacttggtc cccttcgtta atgacatttc
    67981 gttgacgaat agttgctgtt tgtgccgcat catcataaga aaccacttca gcgacaaact
    68041 tgtactcagg aattttacga cgagcaccaa acaactgctc attttcagat ggtgtaccat
    68101 agtaaaatcc tgtagccagt tcacgttggg caaccttcca catctcgtcc accaagtctt
    68161 gtttgatagc ttcaaacttt tcaggacttt caagataggc atccacagcc gccttgtagc
    68221 agttggttac tgttaataca tagtgaatag actccatacg tccttcgatt tttagactgt
    68281 ccacaccatt ttcaatcata tctggaatgt ggtcaatcat agacatgtca acggctgaca
    68341 ttgaaaattc ttctggaatc tcaccctgca aactcttacg ttctttccca aatggcatat
    68401 cgtaaaggtc gtacttccaa cggcatgact gagaacatcc accacggttg gcatcacgca
    68461 tactctagac ggattgtttt gacaattcta atcttttaga ctttgcataa taactgttaa
    68521 acagttgaaa attgacccag ttttaacaag tagtcaaaat accagataaa ggaaaaaagt
    68581 ctttaaaatc ttaaaaacgc atagtatcag gtattgaaca atcttgatat tatgcgtttt
    68641 attgtgggaa gatttacttc attttctctt ggaattgagt tttctcctac ttcaaaacta
    68701 gatgatttgc tatttaaaat agcgttcctt atgattttgg caacctggat taaagcgaga
    68761 aaaacaaaag gggcaactta agctttcttt atattgctta tatgttagta gttttagaca
    68821 aacaccacat aaaataggct tatcctgtat caaagataag ggatacggct caaaagggtg
    68881 attttctaat gaatcatgac accgataaca agcataatac tttttacaat catagcattg
    68941 taaagcaata atatccagct tgctatggta atgaatgcat cttgtttgct tatccactaa
    69001 gaaaccctgt gcctctatca tttccttttc ctttcttaag ctcgaactgt gacgctggtt
    69061 ccatcttcct tataaagatt gatgagtcct tcttttaatg cacgaaccat gtctcctgat
    69121 tgaacgggtt gaggcacctt aatagtcaat agttccattg gatttggagc gcggtcgatt
    69181 ttattgcctt tggcatcatg caaatcttca atataggttt caaaatgacg gaaacctgga
    69241 ccataaaact caacttggtc cccttcgtta atgacatttc gttgacgaat tgttgctgtt
    69301 tgtgccgcat catcataaga aaccacttca gcgacaaact tgtactcagg gattttacgg
    69361 cgagcaccaa acaactgctc attttcagat ggtataccgt agtagaaacc tgttgccaat
    69421 tcacgttggg caaccttcca catctcgtcc actaagtctt gtttgatagc ttcaaacttt
    69481 tcaaaacttt caagataggc atccacagcc gccttgtagc agttggttac tgttgatacg
    69541 tagtgaatag acttcatacg tccttcgatt tttagactgt ccacaccatt ttcaatcata
    69601 tctggaatgt ggtcaatcat agacatgtca acggctgaca ttgaaaattc ttctggaatc
    69661 tcaccctgca aactcttacg ttctttccca aatggcatat cgtaaaggtc gtatttccaa
    69721 cggcatgact gagaacatcc accacggttg gcatcacgca tactcatgtg gtttgaaaga
    69781 gtacaacgtc cagagtatga aatacacata gctccatgga caaaggcttc aatttcaaca
    69841 tctgtacgtt tgcggatttc agctaattct tccattgaaa cctcacgcgc taaaacgaca
    69901 cgagtcaagc ctagctcttt ccagaactca agggtttcat agttagtggc actggcttgg
    69961 gtagaaaggt ggatttcaag gcctggtgct tcagtcgctg caatcataat caaggctggg
    70021 tcagatacga taactgctgc aatcccgata tcacgcagtt tacggaacca ctcaccagca
    70081 ccagcttcat ttccttcgtg cataaccata ttagccgcta catagacctt ggcaccatac
    70141 ttggccgcaa actgcacgcc ttcttccatc tgttcgaaag taaagtttcc cgcacggcta
    70201 cgaagaccat aggcctgacc accgataaag acagcatctg ctccatactg aacagctacc
    70261 tttagcttct ctaaagtccc tgcaggtgat aaaacctcag gacgttttaa tgtttttgtc
    70321 ataatttctc ctatttgcaa tataaaagtt tgacattttt ccttctcatt ttatagtaaa
    70381 taaaggataa aatcaagcct agacggattg ttttgacaat tctaatcttt tagactttgc
    70441 ataataacta ttaaacagtc gaaaattacc ccagttttaa caagtagtca aaaagtctaa
    70501 aaaagtaaaa accagtatcc caagatactg actcgtaaaa atatataaat tagtccttag
    70561 atgactactc ccactctgtt gctcctataa tggaaaagga ttgatacagt ctagaatatc
    70621 gcttttttat ttattattat gatataaaac tgttagaatt gattttttgt tttataccca
    70681 aatatgaata gagacgtagc taataagttg aataacatat ttggaaaaat gagaaatagc
    70741 aatattacta gaacttttag aaacaatcaa tatttaaaaa gaaaaaagct caaagaattt
    70801 attaaaccat gttataatag atatagctat aattttattt ataacaagag gatagaaatg
    70861 accgaattag aaagaaaaaa tcgaaaaatt agctaagaaa tattctgata acttaaacat
    70921 caaagttcaa gagagagttc gtgaaatggc aaatgataat aagagccatt atttgatata
    70981 cagagtttta ggtatttcat ttgaagaagg agaaaatatc gatttgtatc aaaataaagg
    71041 tcgtttttta tacaaatatg ctggttcatt tttagaagaa gctgcagtac tatcctttaa
    71101 cgaaaaattt ggtacagaaa atacttaaaa agttaacatt cctaattctg aaagtacaaa
    71161 acctaagact tttgaaattg attgtttagt cggagaaaaa cacgcatacg aaataaaatg
    71221 gtgggatgca actacagatg gagaccatat aactaaagaa cacactagaa taaaagttat
    71281 tcataacaaa ggatatatac caattcggtt aatgttctac tatccaaata gaactcaagc
    71341 tataaaaatt cagcaaactt tagaaacatt gtataacggt attggaggga aatattatgg
    71401 agattctgcc tgggaacatt taagagcagt gaccggtatt gatttactta gtattctaac
    71461 agatattgca aataaaaaac aggggtaaaa tcaaaatgac agtattaaaa ggagataact
    71521 tagaaatatt aaaaactatt gaatcctcaa gtattgattt aatctatatg gaccctcctt
    71581 tctttacaca gaaaacccaa aaattatcta ataacaaaaa tattatgtat tcattcgaag
    71641 atacgtggac ttcgattgag gattacaaag aatttttgtc tgtaagatta gaagaatgca
    71701 aaagagtgct aaaaaatagt ggcagtattt tcgttcattg tgataaaatt gcaaatcatc
    71761 atattagatt aattttagat aatatctttg gagcagatat gtttcaaagc gaaattatat
    71821 ggaactataa acggtggtct aattcaaaaa agggattatt gaacaatcat caaaacattt
    71881 acttttattc aaagtcaaaa gattttaaat ttaatacaat ttttacagag tattcttcta
    71941 ctacaaatat cgaccaaata ctagtggaac gaaaacgaga tggaaactct aaaactatat
    72001 ataaggttga taataatggt aactatattc tagcaaaaga gaaaaatgga gttccccttt
    72061 cagatgtttg gaatatacca tttcttaatc caaaagctaa agaaagagta ggttatccta
    72121 cacaaaaacc tattctgtta ttagaacaaa ttataaagat tgctactgat aaaaatgata
    72181 tagttttaga cccgttctgt ggaagtggaa ctactttagt agcctccaag attttgaata
    72241 gaaattatat ggggattgat ttatctgagg aagctatcaa tataactcag caacgtctgg
    72301 aaaatgttat aaaaacaagt tcaaatttat tgaataaagg aatcgaagca tatagaacca
    72361 aaactgagga agaggaaaac attcttaaat tattacaggc aaaaattgtt caaagaaata
    72421 aaggaattga tggtttttta cctaaacatt ttcaaaaaaa accgatacct ataaaaattc
    72481 aaaaaaataa tgaatgtctg aatgagagta tctctttatt acagaatgct ataaactcca
    72541 aaaaacttga ttttggagta gttataaaaa ctcattcaga taatttatta tttgattttg
    72601 atacgattcc tgaaaatata atagtagttg accattttga acttacaatc gaaaaatggt
    72661 taagtaaaag tcaacagtta ctatagtttg caaattattt acagaaagaa caaaaaatgc
    72721 tctgaaacac tgatttcaag gcattttttg ttagtttaaa attactccca ttcttctttt
    72781 ccaaacatac aatatatcca aaaccattca aaatactaga ttctattttt tataatatca
    72841 ctaaatccac ctaattatag gacgttttca gatttttagt cccgtcccag tcccagtacc
    72901 ggagaaatat tgttttaata taatatctct ttttgtcttc taagctctta aaagcaaaag
    72961 aacaagtaaa gagtcaagac aaggataaaa agtccatatt agggcaaata aaaagcttta
    73021 agacagatga caaatctaag tcaaataaga aagaccatag caaaggtgca gagagataaa
    73081 tattggcggt cttcggactg cctttatttt tttatccatt tttcaaatca aatttattca
    73141 gactatatat gcacatatac acttaaattc atataaaaac atggcttgta aaaaattact
    73201 ttaatcacaa taatcgcatt taaaattgtg atgtttgcaa gctaaattac ggacttcact
    73261 tggaagtttt cccttgtatc ttttataata gatagaaaat ttgctggcag atgaatatcc
    73321 aacagattct gctatctctt ttataggtag ttcagtgttt aaaagaagag tttcagctac
    73381 attcattctt tttctttgag tgtactctgt aatgctttga caatattttt ccttaaataa
    73441 attttttaat ttagtaccac tcattttaga tattttttca agcgtgcctt gatttacatt
    73501 cgttgcaaaa tgatcatcta agaatcttgc tacatcttca agtgctttat catcatcaat
    73561 ttcaatttta tatttttttc tatttaagta tgtgtcaatt actatactta tccattcatt
    73621 tgcctttgct ttaaagaaaa aatcagcggc aggagcgtcc atcttacaat ttaatatttc
    73681 cattgccact ctttctaagg cctttgtaag tattatttga ttcggttgaa gcaaggttga
    73741 ataaaaagat tctggattaa tgttaataga tgctaaatgt ttttctatta gctctttttt
    73801 aaaaccaatg gaaacagcaa gataacaaca attctcgtgt aataaaaaaa caaaatcatc
    73861 ttttatatta tcaaaatcaa aagtacataa agagtttgcg gtaatagttt gatacggatt
    73921 aaacttttct ccgtttgcac tgacaatgta acttgaataa attgaaacat agtctgacat
    73981 actataagtg ctattttgaa ctacttcctc tttgatataa aaatcatgta tatcgataat
    74041 gaagctgcct ccttcataaa accaatatag gccttctgca taagttgaat tctctttttt
    74101 ccaacaaaat gtatgacctg cacttgaata cttctcattg tttttacatt catctacttt
    74161 catataatct tttacaaaat cataatatga cataacacac tatccctttt agacaatatt
    74221 ccaattagcc ttattaattc aaaactattg tattagtaat tataacagat gtataataga
    74281 aaagcaatga tagatattat caattaagcg aatttatatc taaaagggat attaaagaaa
    74341 ggagatatgc ttatgaagat ttacaaaaaa ctatttgctt atgtccaaga taagaaatat
    74401 cttggggttt tggccataat tttttctgct atatctgctc tacttacagt atatggatat
    74461 tatttaatct acaaatttct agataagtta ataattaatt caaatttatc cggtgcagag
    74521 agtatagcat taaaatctgt tattacacta acaagtggag cgatatttta ttttgtctca
    74581 ggaatgtttt cacacatctt gggatttagg cttgaaacaa atttaagaaa aaggggaatt
    74641 gatggcttag agaaagcaag ttttaggttc tttgacttaa atccatctgg tcaaataaga
    74701 aagatcatag atgataatgc agcacaaact catcaggtgg tagcacacat gattcccgat
    74761 agttctcagg caataatcac acccgtactt gtacttgcac ttggctttat agtaagtata
    74821 agagttggca taattttgct tgctcttact ataattggcg gcttaatttt aggggcaatg
    74881 atgggcgagc aagaatttat gaagatatac caagaatccc tatctaaact aagtgctgaa
    74941 actgttgagt acgtgagagg aatgcaagtt gtaaaaatat ttaaagcaaa tgtagagtct
    75001 tttaaaagct tttataaggc gataaaagat tactcaaagt atgcttatga ttattcccta
    75061 tcttgtaaaa ggccttatgt tttgtatcaa tggttatttt ttggactgat tgcaatttta
    75121 attattccta tagtttattt tatgactagc ttagctagcg caaaggtgat tttacttgag
    75181 cttatcatga ttttattttt atcaggagtt ctctttgttt cattcatgag aatgatgtgg
    75241 tactccatgt atatttctca aggaaattat gcagtagata ctttagaggc gctttacgaa
    75301 gatatgcaaa aagacaaatt agtgcatggt aatatcaata attttaaaaa ctataatata
    75361 gaatttgaga atgttagctt tgcttataat gataaagctg tcattgaaaa tttatccttt
    75421 aatttagaag aaggaaagtc ctacgcactt gtcggttcat ctggatcagg caaatcaaca
    75481 gtagcaaaac ttatatcagg tttttataat gttaataaag gaagcataaa gataggcggg
    75541 atagcaataa gtgaatattc tgacgaagcc ttaattaaag ccatttcctt tgtttttcaa
    75601 gattcaaaat tattcaagaa gagcatttat gataatgtag ctttagctaa taaagatgcg
    75661 acgaaagatg acgttatgag agccttaaaa ttagcaggat gcgatttaat attagacaaa
    75721 ttcccagaaa gagaaaatac aatcataggc tcaaaaggtg tttatttatc cggtggagaa
    75781 aaacaaagaa ttgcaattgc tagagcaatt ttaaaggatt ccaaaattat tattatggat
    75841 gaagcatcag catctattga cccagataac gagtttgaat tgcaaaaagc ttttaaaaat
    75901 cttatgaagg ataaaacagt tatcatgatt gcacacaggc tatctacaat taaagacctt
    75961 gatgaaatta ttgtcatgga tagtggaaaa attatagaaa gagggtctga caaagaatta
    76021 atgtcaaaag atacaaggta taagagcctg caagagatgt ttaacagtgc gaatgaatgg
    76081 agggtttcaa atgaaagagt tttataaaaa aagatttgct cttacagatg gaggagcaag
    76141 aaatttaagt aaagcaacac tggcttcatt tttcgtttat tgtataaaca tgcttcctgc
    76201 catattactt atgatttttg ctcaggaagt tttggaaaat atgggcaaaa gcaatggctt
    76261 ttatatagta ttctcagttt tgactttgat agcaatgtat attttgcttt ctatcgaata
    76321 cgataaatta tataacacaa cctatcaaga aagtgcagat ttaagaataa ggacagcgga
    76381 gaatttatca aaattacctc tatcttactt ttctaaacat gacatttccg acatttcaca
    76441 aacaatcatg gctgatattg aaggcataga gcatgcaatg agccactcaa taccaaaggt
    76501 gggcggcatg gtactgtttt tcccattaat atctgtaatg atgctagcgg gcaatgtcaa
    76561 gatgggttta gctgtaatta tcccatctat tttaagcttt atatttatac ctttatctaa
    76621 aaaatatcag gttaatggac agaatagata ttatgatgtc ttaagaaaaa actcagaaag
    76681 ctttcaagaa aatatcgaaa tgcaaatgga gattaaagca tataatttat cgaaggatat
    76741 taaagatgac ttatataaaa aaatggaaga tagtgagaga gtacacttaa aggcggaagt
    76801 aactacaatt ttaactttgt ctatatcttc aatatttagc tttatatctc ttgctgttgt
    76861 gatatttgtc ggcgtaaatc taattattaa taaagagata aattctctct accttatagg
    76921 atatttacta gctgctatga agataaaaga ctctttagat gcatctaaag agggcttgat
    76981 ggaaatattt tatttatcgc ccaaaataga aagattaaaa gaaattcaaa atcaagattt
    77041 acaagaaggc gatgactata gcttaaaaaa atttgatatt gatctaaaag atgttgagtt
    77101 tgcctacaat aaagacgcaa aagttttaaa tggtgtaagt tttaaagcta agcaaggaga
    77161 ggtcactgct ttggtaggtg caagtggctg cggtaaaaca actatcttga aacttatatc
    77221 aagactttat gattatgaca agggacaaat cttaatcgat ggcaaagata taaaagaaat
    77281 atcaacagaa tctctttttg ataaggtctc tatagttttc caagatgtgg ttctctttaa
    77341 tcaaagcgtt atggaaaata ttagaatcgg aaagcaagat gcaagtgacg aagaggttaa
    77401 aagagcagca aaacttgcaa attgcacaga ttttatagaa aaaatggata aaggtttcga
    77461 tacagttatt ggtgagaacg gagctgagct atcaggagga gaaagacaaa gattatcaat
    77521 agccagagcc ttcttaaaag atgcgccgat attgatctta gatgagataa cagcaagcct
    77581 tgatgttaac aacgagaaaa agattcaaga gtctttaaat aatttagtta aagataaaac
    77641 tgttgtaatc atttcacata gaatgaaatc catagaaaat gcagacaaga tagtagttct
    77701 tcaaaacgga agagtagaaa gcgaaggtaa gcatgaagag cttttacaaa aatcaaaaat
    77761 ttacaaaaat ttaatagaaa agacaaaaat ggcagaagaa tttatttatt aggaggacta
    77821 caatggataa taaaaaatta aaagtaaaag atttagtaag catcggtgtt tttggcgtaa
    77881 tttattttgc cttcatgttt ggagttggta tgatgggctt gattccaata ttgttcttaa
    77941 tatacccgac agtattagcc atagttgcag gaactgttgt tatgttattt atggctaagg
    78001 ttcaaaagcc atgggcacta tttatatttg gtatgatatc accacttgtg atgtttgcag
    78061 ctggtcatac ctacgtagtt gtggttttat cacttatagt aatgataata gcagaattaa
    78121 ttagaaagat tggtaattat aattcattta aatacaatat gctttcttat gcaatcttca
    78181 gcacatggat atgtagctct ttaatgcaaa tgcttttagc aaaagaaaaa tatatggagt
    78241 ggtctttgat gacgatggga aaagattatg ttgatgtgtt agaaaagtta ataacttatc
    78301 ctcatatggc tttagtagcc ttaggtgctt tcttaggagg aattcttgga gcatatatag
    78361 gcaaggctct attgaaaaaa cacttttcaa atggattata ttgtgtggga tactttactc
    78421 cttgcctaat tttatggtgc tatctgaatt aaaccctata gttaagatgt ttttgagtat
    78481 acctattgtt attagaatgt ttattttacc atttatggca gcaagcttta tgataaagac
    78541 ctcggatgta ggcgcaataa tttcatcgat ggataagctt aagatttcaa agaatgtatc
    78601 catacctatt gcggttatgt ttagattctt cccatctttt aaggaggaga agaaaaacat
    78661 caaaatggct atgagagtaa gagggataaa ttttaaaaac ccagtcaaat atcttgaata
    78721 tgtttctgtg ccactactca ttatatcatc taatatatca gatgacattg caaaagcggc
    78781 agaaacaaag gcaatagaaa atccaattgc caagaccaga tacattcgcg taaagataca
    78841 gctaattgat tttgtttatg ttttagcggt tgctggactt attgtgggag gcttaatatg
    78901 gttgaaataa aaaatttaag tcttgattat ggtgaagagc atatattaga tgatatatca
    78961 ctatccatag ccgagggaga gtgcgtgcta tttacaggaa aaagtggaag tggtaagtca
    79021 tctttaataa attcaatcaa tggactagct gtaaggtatg ataacgcaaa gacaaagggc
    79081 gaaataatta ttgatggtaa gaatataaaa aatttggaac tttatcaaat ctcaatgctt
    79141 gtttcaactg tttttcaaaa tcctaagaca tattttttta atgtcaatac gacattagaa
    79201 ttattatttt atttggaaaa tatcggtctt gcaagagaag agatggacag gcgtttgaag
    79261 gatatgcttg agatattccc gataaaaaat cttttgaaca gaaatatatt taatctatcc
    79321 ggcggtgaaa aacaaattct ttgcattgca gcttcttata tagcaggtac aaagattata
    79381 gttatggatg agtcttcatc gaatttagat attaaaagca taagtgtttt ggcaaagatg
    79441 ctaaagatat taaaagagaa aggcataagc ataattgttg cagagcatag aatttattat
    79501 ttgatggaca tagttgaccg tgtattttta atagataaag gaaagcttaa aaaaacttat
    79561 actagaagtg aatttttaaa gctagataaa aatgaattaa atgctttaag tttaagagat
    79621 aaaaaattaa gtaaattaaa agttccttat ttaaaagaag gtggagagta tcagataaaa
    79681 aatcttagct acaaatttac tgatgatgag tgcttaagct taaaagatat ttcgttcaag
    79741 cttgggaaaa tttatggcat aataggatcc aacggacgag gaaaatcaac gcttttaaga
    79801 tgtttaatag gtcttgagaa aaaatcaaaa gaagaaattt attttaaggg agagaagcta
    79861 tctaaaaaag aaagactcaa aaactcttca cttgttatgc aagatgtaaa tcatcaatta
    79921 ttcacagatg aagtattcaa cgagcttaga ttaggagtaa agaattttga tgaagaaaag
    79981 gcgaaaatca ttttaaaaga tttaggcctg gacgaattta ttgaaaggca tccgatgagt
    80041 ttatcaggag ggcaaaagca aaggcttgca atagcatctg ttatgtgcaa gaattctcca
    80101 tttgtctttt ttgacgaacc ttcaagtggt atggattatt ccaatatgat aaaaatatct
    80161 gaactgatta ataagtataa aaccatggat aaaataattt ttattgtttc ccatgatata
    80221 gaatttttaa atgaagtggc agatgaaatt tttgaattat aaaatagagt ctgttaaaca
    80281 tgtctataga actggtaaat tgtctaaaaa tttaaaagat actaacacat attgatattt
    80341 attagaaaat taacttcagg atttttacag tatttataaa ctttataata tgtatttata
    80401 gtattaataa tttccatatc tttagggaaa ttctttattt acttaccata attaaagaga
    80461 tgagagataa atatcggcag tcttcggact gcctttattt ttttacttaa tttaatgcag
    80521 taaatcatac gattgaaagg aatctgcttt atatgctata attaggtagt taatctatac
    80581 atttagaaag gtaaaatata gaattggaga atgatatggg attttcatat aataaattgt
    80641 aaccg
//
LOCUS       DBERXF010000003        78554 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.03, whole genome shotgun sequence.
ACCESSION   DBERXF010000003 DBERXF010000000
VERSION     DBERXF010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 78554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78554
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.03"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(216..563)
                     /locus_tag="ACL8JK_000192"
     CDS             complement(216..563)
                     /locus_tag="ACL8JK_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS1785152.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAALVLDFYRMK"
     gene            complement(674..2449)
                     /gene="spxB"
                     /locus_tag="ACL8JK_000193"
     CDS             complement(674..2449)
                     /gene="spxB"
                     /locus_tag="ACL8JK_000193"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGS1785153.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2656..4899)
                     /locus_tag="ACL8JK_000194"
     CDS             complement(2656..4899)
                     /locus_tag="ACL8JK_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGS1785154.1"
                     /translation="MTEIVKASLENGIQKIRIRSEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFFCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKKNAKLAISQLKKRGLGTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4909..5280)
                     /locus_tag="ACL8JK_000195"
     CDS             complement(4909..5280)
                     /locus_tag="ACL8JK_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HGS1785155.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKNPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHTNLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(5291..5686)
                     /locus_tag="ACL8JK_000196"
     CDS             complement(5291..5686)
                     /locus_tag="ACL8JK_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGS1785156.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5870..5968
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6052..6843
                     /gene="thiD"
                     /locus_tag="ACL8JK_000197"
     CDS             6052..6843
                     /gene="thiD"
                     /locus_tag="ACL8JK_000197"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGS1785157.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGVAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7053..7685)
                     /gene="thiE"
                     /locus_tag="ACL8JK_000198"
     CDS             complement(7053..7685)
                     /gene="thiE"
                     /locus_tag="ACL8JK_000198"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGS1785158.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7678..8481)
                     /locus_tag="ACL8JK_000199"
     CDS             complement(7678..8481)
                     /locus_tag="ACL8JK_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGS1785159.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8481..9005)
                     /gene="thiW"
                     /locus_tag="ACL8JK_000200"
     CDS             complement(8481..9005)
                     /gene="thiW"
                     /locus_tag="ACL8JK_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HGS1785160.1"
                     /translation="MRKHQLQVHKLTILSMMTALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(9010..9702)
                     /gene="tenA"
                     /locus_tag="ACL8JK_000201"
     CDS             complement(9010..9702)
                     /gene="tenA"
                     /locus_tag="ACL8JK_000201"
                     /EC_number="3.5.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HGS1785161.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9713..10363)
                     /locus_tag="ACL8JK_000202"
     CDS             complement(9713..10363)
                     /locus_tag="ACL8JK_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HGS1785162.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10365..11750)
                     /locus_tag="ACL8JK_000203"
     CDS             complement(10365..11750)
                     /locus_tag="ACL8JK_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1785163.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMESLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11751..12311)
                     /locus_tag="ACL8JK_000204"
     CDS             complement(11751..12311)
                     /locus_tag="ACL8JK_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS1785164.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12573..12661)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12870..13499)
                     /gene="thiE"
                     /locus_tag="ACL8JK_000205"
     CDS             complement(12870..13499)
                     /gene="thiE"
                     /locus_tag="ACL8JK_000205"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGS1785165.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALRGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGVKLMRKLL
                     PQMPLVAIGGIQTKHIKDIMKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13501..14283)
                     /gene="thiM"
                     /locus_tag="ACL8JK_000206"
     CDS             complement(13501..14283)
                     /gene="thiM"
                     /locus_tag="ACL8JK_000206"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGS1785166.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPVVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            14385..14567
                     /locus_tag="ACL8JK_000207"
     CDS             14385..14567
                     /locus_tag="ACL8JK_000207"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785167.1"
                     /translation="MKIKEQTRKLTADCSKHCFEVVDRTDEVSNHTYGKVKLTWFEEI
                     FEESYLIKFVNIMSLL"
     gene            complement(14564..15232)
                     /locus_tag="ACL8JK_000208"
     CDS             complement(14564..15232)
                     /locus_tag="ACL8JK_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HGS1785168.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYWAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(15447..15535)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15789..16925)
                     /gene="lctO"
                     /locus_tag="ACL8JK_000209"
     CDS             complement(15789..16925)
                     /gene="lctO"
                     /locus_tag="ACL8JK_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HGS1785169.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKDEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17549..19039)
                     /gene="lysS"
                     /locus_tag="ACL8JK_000210"
     CDS             complement(17549..19039)
                     /gene="lysS"
                     /locus_tag="ACL8JK_000210"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGS1785170.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19179..19313)
                     /locus_tag="ACL8JK_000211"
                     /pseudo
     CDS             complement(19179..19313)
                     /locus_tag="ACL8JK_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            19529..20209
                     /locus_tag="ACL8JK_000212"
     CDS             19529..20209
                     /locus_tag="ACL8JK_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1785171.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLETISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFG
                     NPSTLSRK"
     gene            20169..20846
                     /locus_tag="ACL8JK_000213"
                     /pseudo
     CDS             20169..20846
                     /locus_tag="ACL8JK_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
     gene            20847..21604
                     /locus_tag="ACL8JK_000214"
                     /pseudo
     CDS             20847..21604
                     /locus_tag="ACL8JK_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21616..21858
                     /locus_tag="ACL8JK_000215"
     CDS             21616..21858
                     /locus_tag="ACL8JK_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HGS1785172.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYATILN"
     gene            21900..22481
                     /locus_tag="ACL8JK_000216"
     CDS             21900..22481
                     /locus_tag="ACL8JK_000216"
                     /inference="COORDINATES: protein motif:HMM:NF012707.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGS1785173.1"
                     /translation="MSVDAANRAEYLISNKVDITLANFTVTDERKKQVDFALPYMKVS
                     LGVVSPKTGLITDVKQLEGKTLIVTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLD
                     GRGDAFSTDNTEVLAWALENKGFEVGITSLGDPDTIAAAVQKDNQELLDFINKDIEKL
                     GKENFFHKAYEKTLHPTYGDAAKADDLVVEGGH"
     gene            complement(22561..23208)
                     /locus_tag="ACL8JK_000217"
     CDS             complement(22561..23208)
                     /locus_tag="ACL8JK_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785174.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23205..23903)
                     /locus_tag="ACL8JK_000218"
     CDS             complement(23205..23903)
                     /locus_tag="ACL8JK_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785175.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(23913..24664)
                     /locus_tag="ACL8JK_000219"
                     /pseudo
     CDS             complement(23913..24664)
                     /locus_tag="ACL8JK_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(24664..25428)
                     /locus_tag="ACL8JK_000220"
     CDS             complement(24664..25428)
                     /locus_tag="ACL8JK_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785176.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGTVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25524..25646)
                     /locus_tag="ACL8JK_000221"
     CDS             complement(25524..25646)
                     /locus_tag="ACL8JK_000221"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785177.1"
                     /translation="MYYNGGGDNYIGSGTRLAMAPQFGNHVRIHTSGSWNPDSY"
     gene            complement(26107..26739)
                     /gene="pyrE"
                     /locus_tag="ACL8JK_000222"
     CDS             complement(26107..26739)
                     /gene="pyrE"
                     /locus_tag="ACL8JK_000222"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGS1785178.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFTDAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(26773..27474)
                     /gene="pyrF"
                     /locus_tag="ACL8JK_000223"
     CDS             complement(26773..27474)
                     /gene="pyrF"
                     /locus_tag="ACL8JK_000223"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGS1785179.1"
                     /translation="MREHRSIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            complement(27707..28906)
                     /gene="divIB"
                     /locus_tag="ACL8JK_000224"
     CDS             complement(27707..28906)
                     /gene="divIB"
                     /locus_tag="ACL8JK_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HGS1785180.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEIEESES
                     KEKEEQDKKLAKKAIKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(28916..29974)
                     /locus_tag="ACL8JK_000225"
     CDS             complement(28916..29974)
                     /locus_tag="ACL8JK_000225"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HGS1785181.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(29978..31330)
                     /gene="murD"
                     /locus_tag="ACL8JK_000226"
     CDS             complement(29978..31330)
                     /gene="murD"
                     /locus_tag="ACL8JK_000226"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGS1785182.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(31434..32075)
                     /locus_tag="ACL8JK_000227"
     CDS             complement(31434..32075)
                     /locus_tag="ACL8JK_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785183.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(32077..33495)
                     /locus_tag="ACL8JK_000228"
                     /pseudo
     CDS             complement(32077..33495)
                     /locus_tag="ACL8JK_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
     gene            33662..35008
                     /locus_tag="ACL8JK_000229"
     CDS             33662..35008
                     /locus_tag="ACL8JK_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HGS1785184.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADVYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDENLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFFKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPGRKASLMMH"
     gene            complement(35198..35806)
                     /locus_tag="ACL8JK_000230"
                     /pseudo
     CDS             complement(35198..35806)
                     /locus_tag="ACL8JK_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(35877..36176)
                     /locus_tag="ACL8JK_000231"
                     /pseudo
     CDS             complement(35877..36176)
                     /locus_tag="ACL8JK_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            complement(36540..36794)
                     /locus_tag="ACL8JK_000232"
     CDS             complement(36540..36794)
                     /locus_tag="ACL8JK_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HGS1785185.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(36814..38655)
                     /gene="typA"
                     /locus_tag="ACL8JK_000233"
     CDS             complement(36814..38655)
                     /gene="typA"
                     /locus_tag="ACL8JK_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGS1785186.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            38817..39542
                     /locus_tag="ACL8JK_000234"
     CDS             38817..39542
                     /locus_tag="ACL8JK_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016866 - intramolecular transferase
                     activity [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGS1785187.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            complement(39582..39809)
                     /locus_tag="ACL8JK_000235"
     CDS             complement(39582..39809)
                     /locus_tag="ACL8JK_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785188.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(39898..40278)
                     /locus_tag="ACL8JK_000236"
     CDS             complement(39898..40278)
                     /locus_tag="ACL8JK_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGS1785189.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(40278..40547)
                     /locus_tag="ACL8JK_000237"
     CDS             complement(40278..40547)
                     /locus_tag="ACL8JK_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGS1785190.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            40611..41519
                     /locus_tag="ACL8JK_000238"
     CDS             40611..41519
                     /locus_tag="ACL8JK_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGS1785191.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(41573..42328)
                     /locus_tag="ACL8JK_000239"
     CDS             complement(41573..42328)
                     /locus_tag="ACL8JK_000239"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS1785192.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(42349..43278)
                     /gene="rnz"
                     /locus_tag="ACL8JK_000240"
     CDS             complement(42349..43278)
                     /gene="rnz"
                     /locus_tag="ACL8JK_000240"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGS1785193.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAKKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(43293..43916)
                     /locus_tag="ACL8JK_000241"
     CDS             complement(43293..43916)
                     /locus_tag="ACL8JK_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HGS1785194.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKSFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(43909..45147)
                     /gene="hflX"
                     /locus_tag="ACL8JK_000242"
     CDS             complement(43909..45147)
                     /gene="hflX"
                     /locus_tag="ACL8JK_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGS1785195.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(45140..46024)
                     /gene="miaA"
                     /locus_tag="ACL8JK_000243"
     CDS             complement(45140..46024)
                     /gene="miaA"
                     /locus_tag="ACL8JK_000243"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGS1785196.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVLHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRREQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            46145..46315
                     /locus_tag="ACL8JK_000244"
     CDS             46145..46315
                     /locus_tag="ACL8JK_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGS1785197.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(46363..47202)
                     /locus_tag="ACL8JK_000245"
     CDS             complement(46363..47202)
                     /locus_tag="ACL8JK_000245"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGS1785198.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLKTNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(47299..48258)
                     /locus_tag="ACL8JK_000246"
     CDS             complement(47299..48258)
                     /locus_tag="ACL8JK_000246"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGS1785199.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KSLGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(48385..49263)
                     /locus_tag="ACL8JK_000247"
     CDS             complement(48385..49263)
                     /locus_tag="ACL8JK_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HGS1785200.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DLHEGEPGYSAKLDRDHDGVACELKNAPKGTFKAKQAATTQTDTTSSTASGWVKQDGS
                     WYYFDGNGNLVKNAWQGAYYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGA
                     YYLKSNGKMAQGEWVYDATYQAWYYLKSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGG
                     RYYVGADGVWKEGQASTASSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFD
                     KFSNDAAQYAIDHLDD"
     gene            complement(49313..49930)
                     /locus_tag="ACL8JK_000248"
     CDS             complement(49313..49930)
                     /locus_tag="ACL8JK_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS1785201.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQYLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIISDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(49931..51652)
                     /gene="pabB"
                     /locus_tag="ACL8JK_000249"
     CDS             complement(49931..51652)
                     /gene="pabB"
                     /locus_tag="ACL8JK_000249"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HGS1785202.1"
                     /translation="MHRKTVIDFRTLGERYTFIQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAENYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     KIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     KHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(51713..57265)
                     /locus_tag="ACL8JK_000250"
     CDS             complement(51713..57265)
                     /locus_tag="ACL8JK_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGS1785203.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSVESAPVEEVGGAVDSKTDEQAPVKSESQPSDKPAEES
                     KVEPSVEPVAPREDEKAPTAPVEPEKQPEVPEETVEPKEETKTAKGTQEKGKEGQAPV
                     QEVHPEYKVTTGTVEKSIESELDFTTDVVPDDTKYVGDEVVENPGSKGVQVTKTTYET
                     VEGVETDKVLSTSTEVTKEPVNQQVIRGTKPIEGTLIEESLEKIPFKEVVKEDDQLKK
                     GLEVVAQEGKEGQKKITKTFNTIKGVKTEDAPKVTEEILEEPQDKILKRGTKSFEKPV
                     LTITEIESKDLKRTSDVKYSLENPSKAAIKSITLTLKKGDEIVKTLNVSPEDLTTTLT
                     DLQYYKDYKLETKMVYDRGEGDEEEVLKEEPLRIDLKKVEIKDIIRTDLIKYENQVET
                     DETRLTSVPTDLSNYYLKVTSNDHKTNLLAVQKIEESTIDGKQVYKVIAVADNLVQRN
                     VDNRFEETYTYYIEKPKASQAGIFYDFEELIQAIQTNPAGEFKLGQSMSARNVVPKGK
                     SYITSEFTGKLLSDGDKRYAIHNLEHPLFDKIKAGTVKNINFENIDIDLSNQDNIAAI
                     ANEISGTTRIENIKAIGTITARNNVAGFVNNIKEDATLENVAFIGSINSAGNNSTVGG
                     IAGSNYMGFVNRAYVDATITANNANASMLVPFVQYKAHSWLSGTKGKLTNSVAKGILD
                     VKNTKYVGGITSKTWPYGAVQDNVTYAKVIKGQEIFGSNDVNDGDANPFVSNLFGVIG
                     YSSSEDGTGKDNKNKNKLKHLSKSEADAKVASFNITAAKFVSEPYELNKLNNVSSREA
                     AYESIQDYNADYKLAYKNIEKLQPFYNKDFIVNQANKLDKNNKLNTKEILSVTPMNNN
                     NFVTDLGDANKIIVHYADGTKDYFNLSSSDEGLSNVREYTITDLGIKYTPNIVQKDHS
                     ALINGIVNILSPIELQSNPIYQKLGRTGSNRVNAIKDLYLEESFDHVKANLNILVTKL
                     VENEDHQLNNSSAAQQMILDKVEKNKAALLLGLTYLNRYYGVKFGDVNIKELMLFKPD
                     FYGKNVSVLDRLIEIGSREDNIKGHRTYDAFSEIISKTTLSENLVNFLNYNRRLFTAD
                     VNIYDWFKKATEGNVYIAERASEVDEIKAAKYKVWDNLQSATHRKMILPLLNLNKSHV
                     YLISNYSAMAVGTAEKLGHSSFDGIKNQIEKAADSYRNYFDFWYRLSLDKVKNMLVKN
                     TVTPLWEGYQAPGGWPDKYGKRNNKEDYAPLRELFGPIGKYYGNNGTGAYAVIWDNPL
                     DTRTEVNYIALSMIDEFGISVYTHETTHVNDRAIYLGGYGRRSGTHAEAYAQGMLQTP
                     VPSTWFDEYGALGINMTFYRPNDGNQWYITDPKTLKTREDIDNYMKGYIDTLSLLDYV
                     EGDAVISKHDDKLNQLWFKKVDPIERTVGSKDQYDKVRNMSSDDWKGITLNSVNDLVD
                     NNLMTNRMMNNNIYKPEVFDPGIAYVGIKMMNSIYAGNTSEGAPGAVTFKNNAFRLWG
                     YYGYDKGFLGYASDKLKSQANKEGKQFGDQYIIQKISDGRFQSFADFKKEYYKELLEK
                     ANAGFTPFTIDGETIHNYDELKSLFAKALEEDMVTNKVNGKLVQVKEKVYKKLLQQTN
                     SFKTSIFK"
     gene            complement(57287..57850)
                     /locus_tag="ACL8JK_000251"
     CDS             complement(57287..57850)
                     /locus_tag="ACL8JK_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGS1785204.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(57966..59657)
                     /locus_tag="ACL8JK_000252"
     CDS             complement(57966..59657)
                     /locus_tag="ACL8JK_000252"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS1785205.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFEANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(59654..60391)
                     /locus_tag="ACL8JK_000253"
     CDS             complement(59654..60391)
                     /locus_tag="ACL8JK_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS1785206.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            complement(60614..61726)
                     /gene="msrB"
                     /locus_tag="ACL8JK_000254"
     CDS             complement(60614..61726)
                     /gene="msrB"
                     /locus_tag="ACL8JK_000254"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGS1785207.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            complement(61737..62303)
                     /locus_tag="ACL8JK_000255"
     CDS             complement(61737..62303)
                     /locus_tag="ACL8JK_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HGS1785208.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            complement(62323..63033)
                     /gene="ccdA2"
                     /locus_tag="ACL8JK_000256"
     CDS             complement(62323..63033)
                     /gene="ccdA2"
                     /locus_tag="ACL8JK_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGS1785209.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            complement(63244..64104)
                     /locus_tag="ACL8JK_000257"
     CDS             complement(63244..64104)
                     /locus_tag="ACL8JK_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGS1785210.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            complement(64283..66337)
                     /locus_tag="ACL8JK_000258"
     CDS             complement(64283..66337)
                     /locus_tag="ACL8JK_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGS1785211.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            complement(66349..66603)
                     /locus_tag="ACL8JK_000259"
     CDS             complement(66349..66603)
                     /locus_tag="ACL8JK_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785212.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            complement(66596..67153)
                     /locus_tag="ACL8JK_000260"
     CDS             complement(66596..67153)
                     /locus_tag="ACL8JK_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS1785213.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            complement(67137..68093)
                     /locus_tag="ACL8JK_000261"
                     /pseudo
     CDS             complement(67137..68093)
                     /locus_tag="ACL8JK_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            68185..68544
                     /locus_tag="ACL8JK_000262"
     CDS             68185..68544
                     /locus_tag="ACL8JK_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGS1785214.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            68922..68999
                     /locus_tag="ACL8JK_000263"
     CDS             68922..68999
                     /locus_tag="ACL8JK_000263"
                     /inference="COORDINATES: protein motif:HMM:NF017416.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785215.1"
                     /translation="MLVSTLLFAYSQGIFSGRKIEKWKS"
     gene            69380..69610
                     /locus_tag="ACL8JK_000264"
     CDS             69380..69610
                     /locus_tag="ACL8JK_000264"
                     /inference="COORDINATES: protein motif:HMM:NF013752.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1785216.1"
                     /translation="MNERYQNLKAKECQALLSPQDRQIFAQRKIDVEPVFGQIKACLG
                     YKRCNLRGKRQVRIDMGLVLMANNLLKHSEMK"
     gene            complement(69858..76559)
                     /gene="bgaA"
                     /locus_tag="ACL8JK_000265"
     CDS             complement(69858..76559)
                     /gene="bgaA"
                     /locus_tag="ACL8JK_000265"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adhesin/beta-galactosidase BgaA"
                     /protein_id="HGS1785217.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSL
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTNLNSVDKSVSYVLTD
                     GSVQEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQIFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAKLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDSYETKDLTVEWEEVPAEN
                     LTKAGQFTIRGRVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(76647..76883)
                     /locus_tag="ACL8JK_000266"
     CDS             complement(76647..76883)
                     /locus_tag="ACL8JK_000266"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785218.1"
                     /translation="MKIKEQTRKLAAGCSKHSFEVVDKTDEVSSKHGFEVVDETDEVS
                     SKHGFEVVDETDEVSNHIYGKATLTKFELDFRRV"
     gene            complement(76909..78384)
                     /locus_tag="ACL8JK_000267"
     CDS             complement(76909..78384)
                     /locus_tag="ACL8JK_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HGS1785219.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            complement(78432..>78554)
                     /locus_tag="ACL8JK_000268"
     CDS             complement(78432..>78554)
                     /locus_tag="ACL8JK_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HGS1785220.1"
                     /translation="LGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
BASE COUNT        23135 a        17271 c        14379 g        23769 t
ORIGIN      
        1 atgaatcaac ttcaagatgt catacaagga ctggagaagg aggtgataaa gtccatcgtt
       61 aatcggagat ggactagaat gctttttgaa agcagatgag tattatatgc aatttcttta
      121 tataaaaaga ccggattgct ccgatctttc aatagttcat attctcaatt tctattttaa
      181 aaatagctaa ggttaacgtc aaatgactac gcgacctatt tcatacgata aaaatcaagc
      241 actagagcag caggtccttg aactaataag gactctgttc cccaatcggt tacagttggt
      301 ccgtgtaaaa cctttatacc aagctcgttc aaccgtttgt agttctggtc tacatcctca
      361 acctcgatat gaataatgat tcctgactga aagttttcca aaggaaccaa atgattttgt
      421 gacaacataa ggcagtgact accaatcgta aactgagcaa aaccatcatc agcataatct
      481 gcctttttat ccaagatatg ctccaagtca gcacagactt ggggaacatt tgaaacgata
      541 atatctaatt gatttaaatt catttactct cctccataaa aagaccggat tgctccgatc
      601 ttttaaagtt ctgctctatg aaaatcaaag aataaagtct acaagtttca tatttgattt
      661 tcggcgagag gaattattta attgcgcgtg attgcaatcc ttcttcttcc aagaagagac
      721 ggaatggtac gagttcttct gcttcgtatt tttccttgaa ggctttgata gcttcttctg
      781 agtgaagttt tggatccaat tcaagtactt ctactggaag tggacggtgt tgagtgatgc
      841 gagcatcgat gacaacagtt ttaccttctt tgttcaattt aacagcttct gcaacaactg
      901 catcgatgtc ttcgatacgg tcaactgtga atccaacagc tccttgagct tccgcaattt
      961 tagcgtagtc agcgtttgtg aagtctacac caaacaagtg tttgtttgta tcttcgtatt
     1021 tgttcttgat gaagccgtac tcagcatttg agaagacaag gttgataact ggaaggtcgt
     1081 attgaacgtt tgtgataacg tctgggtagc acatgttgaa tgctccgtca cccatgatgt
     1141 tccatacttg gcgatctgga ttgtctttct tagcagcgat accaccagga agggcaatac
     1201 ccattgtcgc aaagagtgga gatgtacgcc acatgttctt aggtgtcatg tgaaggtgac
     1261 gagtagatgt ttgagtagtg ttacctacgt cgattgagta gatagcgtct tgatcagcat
     1321 gtttgttgat tgcattgtaa acttgataca attgcaattc accctcagtt ttaccttcga
     1381 gtttgttcat gtaatcacgc cagttttggt tgttcttaac gtttgcacgc caccatggag
     1441 ttgattcaac tgggtttact ttgtcaagga tagctttagc tgcttgacca gcatcaccaa
     1501 ggattgaagc gtcaagggca tgacgtttac caagtttgta agggtcgata tcgacttgga
     1561 taaatttttc agtgttcttg aatgcttcgt aaacttcagc aaatgggaag tttgaaccaa
     1621 ggaaaagaac tgtgtctgct tcaaagacca cttcgttggc tggtttccaa ccaacacggt
     1681 aagcagaacc tgtcaaacct tcatagttcc attcgaaagc ttcaaagttt ttaccagttg
     1741 tgatgattgg tgctttgatt ttacgtgaca attcagtaat cacttcacca gctttaacac
     1801 caccaaatcc agcatagata actgggcgtt cagcattgtt caagatttca acagctttgt
     1861 cgatttcaac ttcgttcaaa gcaggagcga tgaatgagcg ttcgtatgaa cctgaaccgt
     1921 agtatgagtt ttcgtcgatt tcttggaaac cgaagtttac tggaatttca acaacagctg
     1981 gacctttttt agaaactgca gcacggcagg cttcgtcaat tacttttggc aattgctcag
     2041 cgtaagctac acgtttgttg taaacagcga taccgttgta cattgggttt tggttaagct
     2101 cttggaaagc atccatgttc aattcgttaa ctggacgtga tccaaggatt gctaggaatg
     2161 gagtgttatc catagctgca tcgtaaacac cgttaatcaa gtgagtcgca cctggaccac
     2221 ctgaaccaac tgcaaccccg attgagccgc cgaatttagc ttgcataacc gctgcaagag
     2281 cacctgtctc ttcgtggcga acttgtaaga agcggatatc tttgtcttca gccaaagcgt
     2341 ccatcaatga gctgagtgtt cctgatggga taccgtagat tgtatctacg ccccatgttt
     2401 tcaatacgtt aagcattgct gcagatgcag taattttccc ttgagtcata atgataactc
     2461 tccttcaatt tttttagact tggagaatac gattacatag aattggaaac gttctccaaa
     2521 tttttactat tccactgtat catatttatg ctgacttttc taaaaatctg ctcaaaactc
     2581 tctattctct attctaatac agttttgaaa gtgtcgtcat ttctgtttta taacaaaaaa
     2641 atctagtcat tacttttagt ctattttact aaaatttaac agaagggaac tggtcagaac
     2701 agatacagaa ctaaaggcca tggctagacc tgccaattct gggttgagag ccagtccaac
     2761 acctgaaaag actcctgctg caatcggaat tccgacaaca ttgtagataa aagcccagaa
     2821 aagattgagc agaatacgat gaaaggtttt cttactcatg tcgaaggcac gcaccactcc
     2881 taaaagatta ttggttgtca acaccaaatc tgctgactcg atggcgatat ctgttccagc
     2941 tcccatagca atccccacat ctgctacact aagggcagga gcgtcattga tcccatcacc
     3001 aacaaaggct actttacctg actgttgcag tttatggatt tcatgggctt tttcttctgg
     3061 caagacgcct gcaatgacct cttcaattcc gatttgatct gcaatagcac gcgccacacc
     3121 agcattgtct cctgtcagca tgactgtccc gagaccacgt ttttttagct gactgatggc
     3181 tagcttagca tttttcttag gaatatcttg caaagcaagc aagcctttga tttcattgtc
     3241 aacagctaag aacacaactg tcttagcttc tttttctagt tcttctagtt tatcttgata
     3301 agtattagaa atatccatgc catccagcat tttagcattt ccaagtaaaa cttgttttcc
     3361 attgattcgc cctgaaacac ctttcccgtg caaggcctga aaattttcaa cagtttgaaa
     3421 ctcaagtcca gcttcactcg ctcgcttaac gatagcctca gccagtgggt gttgagaagc
     3481 atcttccaag gaggctgcca atccaaacac ttctacttcg tcgccgatga catctgttac
     3541 cacaggtttc ccttccgtca aagtcccggt cttatcaaag acaagggttt gaactttctg
     3601 gatttcctgt aagacagttc catttttgag gagaaccccc atcttggcac tacgtcctgt
     3661 ccccaccata agggctgtcg gtgttgcaag tcccaaggca caaggacagg cgataatcaa
     3721 aaccgccact ccgtagagaa gagaggacac aaagctagct ccaagcacaa ccacactatc
     3781 cctgagcaag acgaaccaaa cccaaaaggt catgattcct aaaatgacaa ctactgggac
     3841 aaaaatccct gaaatcttat ccgtcaagtc ctgaatcggc gcacgacttg tctgagcttt
     3901 cttcacaaaa tccacaatct gagccaaaac agtctctgag ccaacttttt ctgctctaaa
     3961 gacaagcgtt ccactatgat tgatggttga gccaatgaca gtatctccaa ctgtcttgtc
     4021 cacaggcaga ctctcacctg tcaccatgga ttcgtcaata ctagagacac cttctactac
     4081 gacaccatca acagcaatct tttcaccggg acgcactcga atcaggtcgc ctaccttgac
     4141 ttgttccaaa ggaacttgga cataactatc atcactcaag acttctgcgg ttttagcttg
     4201 caagtccagt aatttctcca cagcttggga cgtatttttt ctcatttttt cctcaaaaac
     4261 tgctcccaaa agaacgaaaa agaggataaa tccagcactt tcgaagtaaa cagggagacc
     4321 agcaaagaga gcaactaggc tatagaaata agccactaga gttcccagcg caaccaaggt
     4381 atccatgttg gcattgtgct ttttaaaact ggcccaagca ctctggatat atggcttacc
     4441 tgcaactaac ataataggcg ttgttgctag aaaggttccc caatgcatga cttgatgact
     4501 aatgctacct gtcaacatcc caatcatgag aatcacaaga ggcacagtaa agatactagt
     4561 aatccaaaaa cgttgcagga gagatagaga ttttcgagtc ttctcaacga ctgtatagct
     4621 tcccttttgc atcttcatgc cacaaaaaaa ttcatgtcgc cctaattctt gaggtgtaaa
     4681 acgaatgact ttctcctcat ctacgccgat tggttccaag ataccttctt cttcaaacag
     4741 aatttcctta taacagtttg aaggagtagc acgatgaaag gtaatctcag ctggaattcc
     4801 cttttgaagc tggatatggg ctggatgata gcctttttca gatcggatac ggattttttg
     4861 aatgccattt tctaagcttg ctttcacaat ttctgtcata gtctccacct actctacaat
     4921 catcttgccg tgcatcatgt tcataccaca agcaaagcca aattctccag cctgttcagg
     4981 cgtgatttcc actacatact cttcccccat tggcaggttc gtatgtacac caaaatctgg
     5041 aaaaacaatt tgatccagac atggtgaagg atccttgcgg tcaaagacaa tgcgggctgg
     5101 cactgatttc ttgaggacaa tcaactcagg agtatagcct cccatgactt ccactcgaat
     5161 ctcttggtat ccgttttttt gctgggcttt ttgtccagat ttttcaggat ttttgaaaaa
     5221 ccaaaacaag ataaacgcga taagggcaat acaaataatg gttacaatac tatttaacat
     5281 gacgtctcct ttacatacaa ttacatctta cttctgttac agcacttgat ttcttctctg
     5341 aaatcacagc ttccaagtct tccaagtcag tctgagtaaa ttcacattct acaatcaagt
     5401 cagccaacaa attcctaatc ctacgggaac aaaccttgtc tttgatatct tggacaagta
     5461 aatcccgact ttggtctaga gttaaaagcg ctgaataaac aaaggacttg ccttcttttt
     5521 tccgagtcaa acactctttc tcaactagac gagccaaaag tgtctgaacc gtggacttgg
     5581 accagtcaaa ccgctctgcc aaaaccctaa tcaaatctgt actggtctgc tccccctgca
     5641 tccaaataat cttcatgacc tgccattctg catctgaaat ctgcattacc atacctccaa
     5701 aatctacatt tgtcaattac actcaacagt atactcccaa aatctacatt tgtcaattat
     5761 agaaataata ttttcttcga aaaatagaat tttaatcatt tgaaaaacga tttgcagtca
     5821 aatattacta tataaacaat aaaaatatgc tatactaaag aaaaaagaaa acaaccacta
     5881 ggggtgcgta aagctgagat taacgactgt tagatccctc tgactcaatc taggtaatgc
     5941 tagctgatgg aagtggaaat gataatgggg actagcagtc ttctattgcc tttctaaaac
     6001 agactagctt gttcttaaga atacaaactt cagttggttg ggaggtttta gatgacttat
     6061 ttacccgttg ctttgaccat tgcagggact gaccctagtg gtggtgctgg cattatggca
     6121 gatttaaagt cattccaagc gagagatgtc tatggagtgg ctgttgtaac cagtcttgtc
     6181 gctcaaaata ccagaggtgt tcagctaatc gagcacgttt ctcctcaaat gttgaaagcc
     6241 caattggaga gtgtcttttc tgatattcca cctcaggctg taaaaactgg aatgttggct
     6301 actactgaaa tcatggaaat catccaaccc tatcttaaaa aactggattg tccctatgtc
     6361 cttgatcctg ttatggttgc tacaagtgga gatgccttga ttgactcaag tgctagagac
     6421 tatctcaaaa caaacttact acctctagca actattatta cgccaaatct tcctgaagca
     6481 gaagagattg ttggtttttc aatccatgac cccgaagaca tgcagcgtgc tggtcgcctg
     6541 attttaaaag aatttggtcc tcagtctgtg gttatcaaag gcggacatct caaaggtggt
     6601 gctaaagatt tcctctttac caagaatgaa caatttgtct gggaaagccc acgaattcaa
     6661 acctgtcaca cccatggtac tggatgtacc tttgctgcag tgattactgc tgaactagcc
     6721 aagggcaaga gtctttacca ggcagttgat aaggccaagg cctttatcac aaaagctatt
     6781 caagatgccc ctcaactcgg tcatggttct ggtccagtca accatacaac ttttaaagat
     6841 taagaaaaaa aactctctag ttcccacttt aagggaatta gagagttttt atactcttcg
     6901 aaaatctctt caaactacgt cagcttccat ctgcaacttc aaaacactgt tttgagctga
     6961 cttcgtcagt cttatctaaa acctcaaggc agtactttga gcaacctgcg actagctttc
     7021 tagtttactc tttgattttc attgagtatt aattaggaaa gaatgtcatg caactttgtt
     7081 aaaaaggctt gcgtttttgc ctcaatatct tctgcttgca tcaaatcacg tacaacagct
     7141 acaccagcta tgccagtgcc cataagctga tcaatattct ccgaagtcaa gccaccaata
     7201 gcaactattg gaatggcaac cgtttggcaa attgttttca aggttgaaat cagggtgatg
     7261 ggtgcatttt ccttggtggt tgtcggaaaa atggctcctg tccccaagta atctgcacct
     7321 gatttctccg cttccagagc tcttttaacc gttttagcgg tgacaccgag gattttttca
     7381 ggacccaaga cttgtcgggc aaccgaaact gggagttcgt catctccaat atgcagacca
     7441 gcagcatcaa ccgcaagaca aacatccaac cgatcatcga ttatcaaggg tacctgataa
     7501 gcatctgtta tttccttgac ttgttttgcc agttgataat attgattggt tgtgagattt
     7561 ttttctcgca attggactat ggtaacccct gaacggcagg ccgtctcaac ttttgcaaga
     7621 aagctttcca cggaatcttg atagcgattg gttaccagat atagtctaag tgcttctcta
     7681 ttcataaacc tctcctttga tggtatctag ccaattttca tctcttctta ggagcgaaag
     7741 ctgattgagt acttggtaac gaaattcttc caatcccatt ccttgaacaa ctattttctc
     7801 agcagcgata ttgagataag agactgctaa gcaagaagct tcaaaaccag tctttccttg
     7861 gctgagaaaa acggctgtta aggctccaac caaatctcct gtccctgtta tccagtctaa
     7921 ttctgcacag ccatttccca gtacagcgac ctgatttttc gaaacgacga ggtccttggg
     7981 acctgtgact aagaaagaca taccatgata ggtctgacac cagtctttca agacttgaag
     8041 caaatcctcc gtttcttgat ctttagcact cgcatcgacc ccaacgccgt ggtgctttaa
     8101 tccaacaaga cttcgaattt ctgacatgtt tcctttaagg accgtaggtc tatagtctaa
     8161 aaggtctctg actaagctct tacgaatgga tgaagctgtt acgccaaccg catctactac
     8221 cattgggaga caaacttgag ctgcataaga agctgctata cggattgctt tctccttctc
     8281 agctgacaaa tgccccaaat tgatgaagag agcctgactt tgcttagtaa aatcaagaac
     8341 ctcacgggga tcatctgcca tgacaggttt gcatcccaga gccaaaatcc catttgccag
     8401 catctcacaa gaaatctcat tggtcataca gtgaatgagg gaactagagc ctataggaaa
     8461 gggatttgta aattcctgca tcagtctatc ctttcactaa agaaatatcc ctgcactttt
     8521 ttaaagaatt cctgcttgat taaaaatcga aaggcaataa aggaaatcgc tgtaccaatc
     8581 aaggttgctc cgaaaaatcg aggcgtgtag ataaaccagc taagcttagc agctgatcct
     8641 gtaaagagta ccataacagg ataggaaaca atagaaccaa taatacctgt tcccacaatt
     8701 tctcccaagg cagaaaagta aaattttcga ccgtacttat aaaagagacc tgctagaagg
     8761 gctccaaaag tcgctcctgt gagagctaaa ggcggaatcc cttgagtcgt catacggata
     8821 aaggctgtca ctgtagccat ggccaaggca taaacaggtc ccatcatgat tcccgctaga
     8881 atattgacta cactggacat cggtgccatt ccctcaatcc gaaagatagg tgtaaggact
     8941 acatcaaggg cagtcatcat agataaaatg gtcaatttgt gaacttgtag ttggtgcttt
     9001 ctcatgtttc tattcttctc ctttttctaa agactgtaaa tcgctcttcc atgtctggtg
     9061 ttggtaagcc atctcccaaa acttggcttc catatgaaca ctgatgtgga aggcatctag
     9121 cattttttgc ttatctgtct catcactttc tcgatagagc tgattgacca gtgctccctc
     9181 ctctctgatc tgttgctcta actcatccgt aatataagtt tcaatccatt gttgatagag
     9241 aggatttggt gatggtttaa gattaagtga tttgcctata tcatggtata accaaggaca
     9301 aggaagcaag cttgcaaaag ctatggctaa gttcggttct gcaaattgcc tataaatatg
     9361 agaaatgtaa tgataacagg ttggagcgat tggatgttgc tccatttcct ggtcgttgat
     9421 ttccaattcc ttgaaaaatt gttggcgaat aaataactca ccctccacta aaccctgagc
     9481 attttgtttc aagagtcttt tcatctcttg gtttgaagtc ttatcagcca aaagatgata
     9541 gatttctgag aaagccttca gatagtaggc atcctgaatc aggtaatagc ggaaaatggc
     9601 aggttctaaa ttcccctctt gtaattgtaa aataaaggga tgatgaaagg aagcctgcca
     9661 agctttcttg gataattcca tcgcaatatc tgtaaattcc ataataactc ctttataaaa
     9721 atagactggt ttgaagcaat aaaaagaaaa gcaggtagat taattttgtt tttttaggaa
     9781 tataaaaagt ccgatagcta ttcttcaact gtgcatgttc gtcatatccg tgagcagata
     9841 gagctctcag gtaaagatgg cgccacctaa agactgtcat cagaacctta ctgtaaatca
     9901 agggcgacca aaaatgtagt ttttgaccac gtaataggca agcttctttg agggacttga
     9961 tttcttgctg aatgagagga aaagaattga ataccacaat caaggcatag gaccaagagc
    10021 gtgatagccc cttttgagcc aagtacaaga gaagctcttt tagtgaaata gaggaaacaa
    10081 agacaaggcc gatacaaact gtcacaaagg ccctcgttcc aagcatgact gcctgtgaag
    10141 catctccgtg taactgaact gcccagtagt tggcaaaaga tggtaaaatg gcaagtatga
    10201 tcatccaagc taacatttta aatcgacggt aatagagcat aaagagaata caaaatgcga
    10261 ctaccgaaag attcagagca atcgaaggaa tgaaagatgt ttccaaggat aaaatcagca
    10321 agaagagact gataatcggt gtctgggttg ctactttgac catactatct cacctcccct
    10381 tgggtattgc tactctgaga tgtaagtggt ttggtaatgg tcacttcttt cacatgccga
    10441 agaccctgac tagtcatctc aatccaataa tcaaccacag aaatcaaagg gtctaaacga
    10501 tgactaatga gcagaaaact tcttccttga ttcctctcct ccacaatcca cttgcaaaaa
    10561 taatggcagg ctctatcatc caaacctgca aaaggttcat ctagcaagat cacggaagcc
    10621 ttactggtca agatggtcag gagctgaaga attttttgct gaccaccact taattgatag
    10681 ggactcttat cgactgcctg ctccaaatca aaatatcgta aagcttgaaa aatccgctga
    10741 tttctttcag aatcaggtcc atctaattga agctcctctc gcagactgac tcggataaac
    10801 tgcttctcag cttcctgaac aacaccagtc agatcacgat acaaactctt tttctttttc
    10861 aggaccgaac ccttccatgc aatgcgcccc ttatactttt gaaattgaag aatagaccga
    10921 aagagggttg atttcccgac accattgtca cccaggatac aggaaatccc ttgatagaat
    10981 gtgaaatcag caattgaaaa gagggggcga tttccaaact cacaagtcgt tctatccata
    11041 tggaatagtt ccgggctaga agcaacttcc tttgaagcaa cctgtgtcat ctcataggaa
    11101 gggatttgaa acacttccct tagttttccg tctcttagct caaccatatg gtcgatatag
    11161 gctttatagt cagataaatc atggtcgcac aaaataactg tctttccatc aagagccaac
    11221 tcttttagaa tctccaatat ctcgattctg ctcttgcggt caatggaagc aaaaggttca
    11281 tccaagagat agaccctagg attcatggca aagaggacag ccagcgctgc tttttgcttt
    11341 tccccacctg ataggtgatg aatgggacgg tgtaagattg cctcgcaacg acattgctgg
    11401 acaacctctg ctattttaga atcaatttcc tgaaggtgat agccgatatt ctccaaggtg
    11461 aaaatcagct cctcaaacaa gctctccatg gtaaattgat gattgggatt ttgaaagaga
    11521 atgccaacct tctggacacg tgcgatgata gaaagttgac tgacctcgct cccatctatc
    11581 aggacttgac cactataggg aagagaactg acttgagcaa tgacttgaaa aaggctggat
    11641 tttcctgaac cactgctccc aactaacaag gtaaaggctt gcgcatgaaa agtaaaatca
    11701 aacggctcag agaagattgg ggactgaatc gctcgtagtt ccagacccat ctatgctttt
    11761 cctccagttg caaactgatg atagagtttg acaatggcac gaaccaagat ggtacagaag
    11821 aaataaacag aaataaaacg taccacaagt aaggaaagga caaacggaag ggaaaaggcg
    11881 tagtaaccta acttaatgta ttcatagaca aagctaacaa gcgtaatccc aatactatta
    11941 gcagttagag agagccaact ttcatagcga ttcttagtta cgataaaacc aaattcactt
    12001 cccaaacctt gaaccaagcc agacaaaaga gctcctagac caaattggct accataaagg
    12061 acttcagcaa gcgcagctag cacttctcca atcgttgcac ttccgactct cggaacaaag
    12121 atggcagcaa tgggcgcagc catacaccag agaccgaaga ggatttcatt ggcaaaggcc
    12181 tgcaaaccaa gaggtgttaa gagtagactg agaatattat acacatatcc tgaaccaacg
    12241 aaaaccccac caaaaaagat agacaagaaa gcaagcaaga taacatcttt taactgccat
    12301 tttttcaaca taaaaaactc ctttttttaa agaaaagtgg ggcactcaag aagaccgacc
    12361 taaatacttt gtatagcaga ctgaatttag aacagtacac aagaatgcta aaatatttct
    12421 agaaattaat ttgaattttc taattgattt gttcgcatct tatttcaatc tactatatca
    12481 tcttcatcca gtttcgtaaa agaaaaaact ctaattacag atacgaatta gagttcagct
    12541 tacaagatta gacagttctt ttcgacatac gaaaaaaaca tttcacattt cccttcgcca
    12601 gtcttaactg tatcaggttc aatgggtatc atctcagcct aaagcacccc aaatgccttt
    12661 attatttaat tatgtgatta ttataacaca cattttatac tagttcaaga aattgaactg
    12721 gaaatacagc cttgcactca caaagacagc agatctttct tttgcaaaaa acaaatgacc
    12781 tgtttgatga attagctatt caagctgaat ctagacatag ttttttaaaa aaggaaaatc
    12841 ctacttactt agaatccaag gatagatatc tattgttcac tcatttcccg aacagttttt
    12901 tctatatttt ttgcatacga tattgccgaa atgattgaaa cgccgtcaac attggtcttc
    12961 ataatgtctt taatatgttt cgtctgtatc ccaccaattg caactaaggg catttgtggc
    13021 aatagttttc tcatcaattt aacaccttca taacctatag caccaccagc atcatccttt
    13081 gactgggtat caaatacagg accaacacca acataatcta catattcaac ttttgattgt
    13141 tgaaattctt cctcgttttt tatagaaaga ccaattattt tatctggcat caattttcta
    13201 atttcatcaa caccaatatc atcttgacct acatgtacgc catcagcgtc aatttccatt
    13261 gccaaatcga tatcatcatt aacgataaac ggcacattgt attttttaca aagttcttta
    13321 atttggatag ctagctcaag tttttctaag ccttctaaag caccctcacc tttttctcga
    13381 aattgaaata aggttatacc acctcttaag gcttcctcaa cgactgtata tagatttttt
    13441 ccttggcaag tagtcgttcc acaaataaaa tatagtttta gtaattcttt atgaaacatc
    13501 ttacttcact cttttgaatt cctttacatc ttcatctgta atctcgtata aggcatttat
    13561 aaattcaact ttaaatgtcc caggaagatg tccatttgga cgtttttctg ccatttctcc
    13621 agcgatattg taaaccaaca ttgctgtttc taatgatttc aattcttgac ctttttctag
    13681 tccgataaag cttgctacca ctgcccctaa taaacatcca gttccaataa cttttggcat
    13741 catggcacta ccattatgaa tcgttaccac ttctccattt accgcaatag catccacttc
    13801 acctgttact actattggaa tattgaactt ctcatttgct gctagagcaa tctcgtcaat
    13861 attatctact cccgcactat ctactccttt agatgccaca tctattccta ctaaagaggc
    13921 aatctctcca gcattccccc taatcgcagc tagtttgtaa ttgttgatta aatcatctgc
    13981 tacttttttt ctatattctc ctgctccaca ggctacagga tctaaaacta ctgggacatt
    14041 atatttctct gcaattttca gagcagcttg gtataatttc caattttcat ctgtcaatgt
    14101 tcctatgttt attaataaac caccagcata ctttaacaaa tcctctaaat ctgctggaaa
    14161 ctcactcatg gctggtgagg cgcccagtgc tactaatcca tttgctgtga aattttttac
    14221 tacatcattg gtgatacaaa tgaccaatgg tgctttttct tttaataatt ttaaacttgt
    14281 catattgaaa tccttccttt tcactttata cgatctactg atttcgattt atttctatct
    14341 ttcgttaaga atttttttca tttacattga atgatttata ctcaatgaaa atcaaagagc
    14401 aaactaggaa gctaaccgca gattgctcaa aacactgttt tgaggttgtg gatagaactg
    14461 acgaagtcag taaccatacc tacggcaagg tgaaactgac gtggtttgaa gagattttcg
    14521 aagagtctta cctcatcaaa tttgtaaata tcatgagcct tctctagaca tcgtaaccaa
    14581 tatcaaaaaa agctaattct aaagcgactg cttgattcca tcgttgctga agttctgtca
    14641 aatcttctcg atttttaccg acacgattga gttcgtcaac cagaaattga acccactctg
    14701 caaagaaagg acctctgtgg agattgatcc attccgaatg aatatagact tcaggtagag
    14761 ccaaatcttt agaaccccag tctaaataga gaccttctgc aatgaccagc ataaccaaaa
    14821 gatgggcata gtctgatgaa gccactgccc aatacattag atcctgaaag gcttttgtta
    14881 cagggtgcaa agtcacttct agatagtcat tctctgctac ttttaactct ttaaaagcct
    14941 tttggaaata accatcttca tctgcttcaa gaaagcctag ttgcttggca aaacgaagct
    15001 tggattcaag tttatctgcg tgagctacgc aggcacccag catggataag aaggcatcaa
    15061 agaagtgata atcttgaatc agatagtcct ttaagacctt attctcaatt gtccccgcaa
    15121 aaagttcctt aacaaaacga tgattgattg cagcctgcca atccttctga ctgcttttta
    15181 ataattctcc aacagtcaaa cctggctgaa atgcatagtc ttgtgtttcc atatttactt
    15241 ctcctctctt tacttgttag taattaataa aacaccaaga aatatcaagc aaaatcgtaa
    15301 ttccacttga tccttttaaa acacatcgag agtatttgca gagagctaac taaacaagcc
    15361 tatccagttt atataaacaa aaaactccaa ttacaatcaa gaattagagt tgacttacaa
    15421 gattagaccg ttcatttcac catacgaaaa aactgttcac atttcccttc gccagtctta
    15481 actgtatcag gttcaatggg tattatctca gcctaaagca ccccaaatgt ctctattatt
    15541 taattactga accagtatag caaaaaatga aagccctagc aagatatttg accgaaaaat
    15601 atctttatat ataatatatt gaaactggaa tagtacacct ctacttctaa aacattgtta
    15661 gaaatcgatt taactgtcct gattaatttg tcctattctt atttcatttt attatagttt
    15721 tcgatagcga tttattcttc caatacacga agaaaaacct ccacattcag tggaggcaat
    15781 ctgttttatc aatacaattt taagtcacga gggtcaactg ggaaggttgg gttgtatgga
    15841 ttgtgacgga gcttaaagtg tttgacatct tcaatggtct gagctccaga caattgcata
    15901 actgtcttca attccgcatt caagtgttca aagacttgac gcacaccgac actaccaccg
    15961 agagccaagc cataaataac agggcgacca atagctacca agtctgctcc tgaagccaag
    16021 gctttaaaga cgtgttgacc acgacgaaca ccagagtcaa agacaatcgg cacacgtcta
    16081 tcaactgctt ctgccacttc ttgaagcgag tcaaaggcag ctggtccacc gtcgatttga
    16141 cgaccaccgt ggttggttac ccagatacca gaagctcctg cagcaagcga acgttcaacg
    16201 tcctcacggc attgtggtcc cttgacatac acaggaagac cagagtattc agcgataaat
    16261 tctacatcgc gtggagacaa gcgttgttta gctgatttgt aaacaaagtc cattgattta
    16321 ccagcacctt ctggcaggta ttcttcaaca atcggcatgc caactgggaa gacaaaacca
    16381 ttacgcttat ccacttcacg attcccccct acagtagcat ctgccgtcaa gacaatcgct
    16441 ttataacctt catccttcac acggtccatg atgtggcggt tgataccgtc atccttacta
    16501 aagtaaaatt gaaaccaatg aggtgtccct tgaagggctt cagaaatctc tggaaggtca
    16561 acagtagagt aagaactggt tgtataaaga gaaccaaact catgcacacc acgcgcagtc
    16621 gccacttccc cctgttcatt tgccaattta tgagccgcaa caggtgccat aatgattggc
    16681 gaagatagtt tttcacctgc aaattcaatc tctgtacttg gattttcaac atcgcaaagt
    16741 gtatgaggaa cgatgagttt gtggttaaag gcgcggatat tctctcttaa agtgaaagta
    16801 tcttccgccc cactagcgat atagccaaat gctgctttag gaataacttg ttgcgccatt
    16861 ggctccaaat cataggtatt gatgaagtct acatgacctt ctgcattgct tgttttgtat
    16921 gacataaact gtcctcctcg attaagtaag cgtttgcttt ttactataca actataataa
    16981 ctcttttttc aatcattttc aagagttttg cttaaaaacc atcttatttt ttcatacaat
    17041 atactagccc tactttcctt aaactctaaa ccttagtcta tattaagtga atcgttgaga
    17101 ttttttgctg ccaggcattt gaactacttt tttatttgct gattctatct actaatacta
    17161 taaaaaacaa gtgaataaga caccagaaca tcctctaata ggacctatgg acttatatca
    17221 gtcccatata tactgtttaa gcaagatact atcctagttg acgctaactt cctatcccac
    17281 ttattaattt tttatttata gtgaatctga acaaatcaat tggggaatcc aagtcaattt
    17341 ctagtacttt ttgaaaagtt tcagcgtact atcgtaaaat gaaataaaac atgcacaaat
    17401 tgattaggga atttaaacca atttctaaca atgtcttaga aatcaaagtg tactatttca
    17461 atttcaatac actacacttc attttctcct taaattcagt ctctttttga ataaaaaaat
    17521 cctctggtaa gagccagagg ataagaattt atttcattgt tgggaagagc aatacatcac
    17581 ggatagttgt tgtatcagtg aggagcatgc agagacggtc gataccgatt cccaaaccac
    17641 ctgttggtgg cataccgtat tcaagagctt caatgtagtc atagtcgatt cctgtcgctt
    17701 catcatcacc aagttctttg gctttagctt gggcttcaaa acggctaagt tggtcgattg
    17761 ggtcgttgag ctcagtaaag gcattaccgt actccttagt catgataaag agctcgaaac
    17821 ggtcagtaaa gcgttggtct tcaggatttt tcttagcgag tggagataca gctactggat
    17881 gtccatagac aaaggttggt tggattaaag tttcttcaac aaactcttca aagaaggcat
    17941 tgatgatgtg accaacctca gtgtagtgtt tctcaactgg aactttcttc tcagcagcga
    18001 tagctttagc ttcttccaaa gtcatgtctt gccagaaatc gacaccagta atttctctga
    18061 tagcatccac catatgaaca cgcttaaatg gttcgttaat cttgatttca gtaccttgat
    18121 agttgactgg gccatcgccc ttaactgatt tagcagcatg ttggataatg ccttccgtca
    18181 agtccatgat atcttggaag tctgcataag cttggtaaac ttcgatagaa gtgaactcag
    18241 ggttatgagt agcatccatt ccttcgttac ggaagatacg cccaatttca tagacacgtt
    18301 ccataccacc cacgataagg cgttttaagt gaagctcagt cgcgatacga agcaccatgt
    18361 caatgttttg ggcattgtgg tgggtgataa atggacgggc agcagcacca ccagcttcgt
    18421 tgtgaagaac aggtgtttcc acttcaagga atcctttttg gtcaaggtaa cgacggattt
    18481 cagagatgat ttttgaacga gtgacaaaac gttcaaagct ttcacgatta gaaatcaagt
    18541 caaggtaacg tttacggtaa attgtttcaa cgtctgtcaa accatggaat ttctcaggaa
    18601 gaggacgaag agccttagac aagtgtgtga tgtgggttgc cttgatagag agttctccca
    18661 tatccgtacg catcacttca ccttcgacac caaggaagtc accaagatct gcttttttga
    18721 agatttcgta gttttcttca ccgacagcat ccttacgaac gtagatctga atctggcctt
    18781 cgcggtcttg aaggtgggca aaaccaactt ttcctttacc acgtttggtt atcaagcgtc
    18841 ctgcgatagt agctgtttcg tttttatcgt gtaattgttc tttatcgagg ttggcatatt
    18901 tatcttttaa ttcttgtgaa tttgcagtac gttcaaaacg ttttccgaaa ggatcgattc
    18961 cttgttcgcg gagcgcagcc attttttcac ggcgaacgat ctgctggtca tttagttctt
    19021 ccatatgttc tgtagacatg ggatcctcct agttttactc aaaattgaat acgatgagtc
    19081 attttttgcg atactcccat tttatcataa ataagcaaga aattcacgga taatctttaa
    19141 aaactaaaaa gaacctgacg ctaaaatcac tggaaagaag tgaaagtatc tcccgcccca
    19201 ctagcgatat agccaaatgc tgctttagga ataacttgtt gcgccattgg ctccaaatca
    19261 taggtattga tgaaatctac atgaccttct gcattgcttg ttttgtatga cataaaatgt
    19321 cctccttaat aagtaagcgt ttactttgta tattataaaa atatcttaac tcttttttca
    19381 aaacttttca aatattttgt ttggaaattt cagaaatttt atgtctatgg taaaaaatcc
    19441 ttataacggc aataaaaaat agatattatc caaagaagat tttaagtgct acaataactg
    19501 tattatttct agatgggagg ttctattttt ggattggtcc attgttgaac aatatctacc
    19561 actatatcaa aaggcattct ttctgacctt gcatattgca gtttggggaa ttttgggatc
    19621 ctttctgctc ggtttaatcg ttagtatcat ccgacattat cgaatccctg ttttggcgca
    19681 agtagcgaca gcctacattg aattgtcacg taatacgccc cttttgattc aactcttctt
    19741 tctctacttc ggtcttcccc gaatcggcat tgtcctatct tcagaagtct gtgcaacgct
    19801 tgggcttgtc tttttaggag gctcctatat ggcagaatct ttccgaagtg ggctggaaac
    19861 catcagtcaa acccagcagg agattggcct cgctattggt ctgacacctc tacaggtctt
    19921 tcgctatgtg gttcttccgc aagcaacagc ggtggcactc ccctccttta gtgccaatgt
    19981 cattttcctt atcaaggaaa cctctgtttt ctcagcagtg gctttggccg acctcatgta
    20041 cgtcgccaag gatttgattg gtctctacta tgagacagac attgcgctag ctatgttggt
    20101 agttgcttat ctgatcatgc tgctacccat ctcactggtc tttagctgga tagaaagaag
    20161 gacccgccat gcaggattcg ggaatccaag tactctttca aggaaataat ctcctgagaa
    20221 tcttacaggg gttgggcgtt acgattggga tatccatcct gtctgtcctc ttatccatga
    20281 tgttcggaac agtcatggga atcatcatga cctcccattc tagaatcata cgatttttaa
    20341 cacgattgta tctggacttt atccgtatca tgccccagct ggtgctactc ttcatcgttt
    20401 actttggctt ggctcgaaac tttaatatca atatctcagg tgagacttca gctattatca
    20461 tttttaccct ctggggaaca gctgaaatgg gagacttggt acgtggagct atcacttctc
    20521 tccctaaaca tcagtttgaa agtggatagg cactcggctt gactaatgtt caactttact
    20581 accacatcat catcccacaa gtcttaagaa gactgctacc gcaggctatc aatcttgtca
    20641 ctcggatgat taaaaccact tcattagttg ttttgattgg ggttgtggaa gtgaccaaag
    20701 ttggacaaca aatcatcgat agcaatcgcc tgaccatccc aactgcttca ttttggattt
    20761 atggaaccat tctagtctta tatttcgcag tttgctaccc tatttccaaa ctatccactc
    20821 acttagaaaa acattggaga aactaaatgt ctgaaactat cttagaaatc aaggaactaa
    20881 aaaaatcctt cggagacaat cccatcctcc aaggactttc tctagaaatc aaaaaaggga
    20941 agttgttgtc atcctagggc catctggttg tgggaaaagt accctccttc gttgcctcaa
    21001 cggcttagaa agtattcaag gtggagatat tcttctggat ggtcagtcta tcgttgaaaa
    21061 taaaaaagat tttcacctag ttcgccaaaa gattggcatg gtctttcaaa gttatgaact
    21121 ctttccccat ctggatgtct tacaaaacct catcctaggc cctatcaaag ctcaaggaag
    21181 ggacaagaaa gaagtaacgg aagaagcttt gcaattacta gagcgtgtcg gtttgctgga
    21241 taaacaacat agctttgccc gtcaattatc tggtggacag aagcaacgtg ttgcaattgt
    21301 ccgtgccctc ctaatgcatc cagaaatcat cctttttgac gaggtgactg cttcgctgga
    21361 tccagaaatg gtgcgtgagg tgctggaact tatcaatgat ttggcccaag aaggccgtac
    21421 catgatttta gtaacccacg aaatgcagtt tgcccaagcc attactgacc ggattatctt
    21481 cctcgaccaa gggaaaatcg ctgaagaagg aacagctcaa gccttcttta ccaatctgca
    21541 aaccaaacga gcccaggaat ttttaaacgt ctttgacttt agccaattcg gctcatatct
    21601 ataaaggaga ttcttatgaa actattcaaa ccactcttaa ctgttttagc acttgccttt
    21661 gcccttatct ttatcactgc ttgtagctca ggtggaaacg ctggttcatc ctctggaaaa
    21721 acaactgcca aagctcgcac tatcgatgaa atcaaaaaaa gcggtgaact gcgaatcgcc
    21781 gtgtttggag ataaaaaacc gtttggctac gttgacaatg atggttctta ccaaggctac
    21841 gctacgatat tgaactaggg aaccaactag ctcaagacct tggtgtcaag gttaaataca
    21901 tttcagtcga tgccgccaac cgtgcggaat acttgatttc aaacaaggta gatattactc
    21961 ttgctaactt tacagtaact gacgaacgta agaaacaagt tgattttgcc cttccatata
    22021 tgaaagtttc tctgggtgtc gtatcaccta agactggtct cattacagac gtcaaacaac
    22081 ttgaaggtaa aaccttaatt gtcacaaaag gaacgactgc tgagacttat tttgaaaaga
    22141 atcatccaga aatcaaactc caaaaatacg accaatacag tgactcttac caagctcttc
    22201 ttgacggacg tggagatgcc ttttcaactg acaatacgga agttctagct tgggcgcttg
    22261 aaaataaagg atttgaagta ggaattactt ccctcggtga tcccgatacc attgcggcag
    22321 cagttcaaaa agacaaccaa gaattgctag acttcatcaa taaagatatt gaaaaattag
    22381 gcaaggaaaa cttcttccac aaggcctatg aaaaaacact tcacccaacc tacggtgacg
    22441 ctgctaaagc agatgacctg gttgttgaag gtggccatta actcttaaaa gggactggat
    22501 tttaagctcc aatccctttt taagatttta cctataacat cctgagtcta tctaagatgt
    22561 tcaatctgaa cacagtgtac atactttatc ttctattgca tatactttat cacataagat
    22621 acgaatatcc tcttcactat gactagcaat caaaattgtt gtcccttttt cactagagag
    22681 ctttctaaac aatgttctca tattttctac acttgattta tccaaggcat tcataggttc
    22741 atctagtaaa agaatagagg gattctccat aattgcttga gcaatcccta gctttttcct
    22801 catacctagc gaataagttt taactttctg gtctttttgc tcatatagac caactatttt
    22861 cagtgtatca ttgatttcct gattaccaac tactcctcgt atgcttgcca aatattgtaa
    22921 attcttaaag ccactataat aatttataaa accaggttct tcaatcaaag ctcccaaatt
    22981 agctggaatt tttctctcag gaacaatatt ttccccattg attaacactt ctccataaga
    23041 cggactatat aaaccagcta ttaatttaaa caatacactt ttccctgagc cattcgcacc
    23101 agtaattcct ataatttccc cctgtttaca actaaagtta aggttttgaa aaacacatgt
    23161 cttttttaat ttcaactcaa tattttttaa tatgattatt tcattcattc tataaacctc
    23221 ctcttttgac gagtgaaata gaaaatgctt tgaaaaagaa agactaaaaa tagcaactga
    23281 agaaataaat ctcgtcctat atctccattc cctcgattca aaatataaaa tagataatta
    23341 gttcgatttc ctacaaatag accaccaaac acaatcatga gtaaaaagaa actaacgcaa
    23401 gcaaagttca tttgtacatt cgctcctagt gcgtataaca taaagcaaaa caagactaac
    23461 acacaagcat tcaaagaatc aactataaac aaaactccta tatcccagtt tggtaactgt
    23521 aacataaatt gaatcactag aacttttacc atgattaaaa tgagtccata aagaaaacag
    23581 gtccaaatct gatacctaat ccagagctta atagaagaaa atcgaatcac ttccataaag
    23641 aaatcggatg ctcttctacg atatacaact gctagaaaaa atgtatgaat aataaaccaa
    23701 tgaagcaacc atatagataa gactaaaaaa gagttttgac tcagattagg cccttttaaa
    23761 atttctataa caagtctatc atttccttct aaccaatacc ataatcctaa acaaatcaat
    23821 atccaaaaaa gaacataacc ccaaaagtac ttggtataga ttatctgatt caacctccac
    23881 atgtgactac ttaactttcc catttccaac ttttacactc tcctccagtt tctatgaaca
    23941 gaaaatacag tcaatggaat tatgatagat agtaatgtaa gccaataaat caatgcatac
    24001 ggattggaat ttaccatata ctgaaaaatt ggcaataatc caattatccc attgtccaac
    24061 tgataaatcc agaataagga ttctacaaat aaaaaagtaa acagaaatac taagctcatg
    24121 tttgattttt taaaccaaga aaaactgcta atagtaagta aggataaaaa gaaatagtat
    24181 gctatataag agaaaaaaaa tcctataaag aaactagcat tgtttgcaat acttatacca
    24241 taaaattctc ttaaaaaatc aacctccttt atctccaaag agaagctaaa accattacta
    24301 aatgcaatta gaaaaatcaa taaaaataaa gtcgccgtcc aaatccccgt actaagagct
    24361 gctaatttga aactaaaact ggtaaagtgc ttaattgatt tcagacgaat gcgacactcc
    24421 aacctattaa aatagttatt catcaaataa aaaaagaaca atatatatgt gaacggaaag
    24481 caatatactc cagtcgtcat atcttgaagt aaaactaaga tccattctaa tacatttgga
    24541 tggattgaat attggcgaca gcgcaataaa tatactgtac tagataaaac acaggatagc
    24601 agtaatataa ataaaccaat actgataaaa aatctttttt gtaaaattga acaaattgtt
    24661 tcattatacg tagtcctctg aatgtagaaa aaatgtacca taaacaacca aacaactaac
    24721 aaataaaata aaagcaagat gcccactaac taaggaaaga ctgatatctt tctgatatcc
    24781 caaagctaat gttgtcacag gttctaagta agatagccct aaaatagccc aaaaaatacc
    24841 accaaccatc atataggcaa ctgggatgaa aatagctcct atttttttct tcactagcaa
    24901 agcactagct agtccaaaaa tagagaacac agtgccccaa actccatacc agagagtcgt
    24961 tacaagacta tagagaaact gattggaatc aaataattct tttaaggcac cactataatc
    25021 tccaatataa atttcctgat aaggagtcac taaaagatta attcctaata ataataaata
    25081 ggggagaaaa aagactagaa aagaagaaat aattacagta ctacccacaa tagccagata
    25141 cttcttttta gaaattcgac acaattgtgc tgttagaaaa tgactctcag catcctctat
    25201 tatctgacta gaatagggca gtgtacagat aagtgcagct actaggctaa tcggtgaaaa
    25261 tcctcgaata gaagaagcgg caaaaaaaat cgataaacct tcaattttat aaataccatt
    25321 gaaagcaagg aaatttccta aactcatgca aagaagggtc aaaaataaag acatataaaa
    25381 tcgaggtgat tgaacgactc gtacaagatt acaaatgaaa aattccatcc ttactcctcc
    25441 ttataataaa aatagggtgt agcattcttt tttcatgcta cacccacaat caaccatctc
    25501 taaggcttac tctgacaagt aagttaataa gaatctggat tccaagaacc tgaagtatga
    25561 attcttacat gatttccaaa ttgtggcgcc atagctaatc tagtaccaga accaatataa
    25621 ttgtcaccac ctccattata gtacatgaca atcctagagc cagaccccaa tgaatatacc
    25681 ggggtaatat ctgacccact ataggcgcta cgaatagagg tatttaacct tttaccgcca
    25741 ccagtgctgt cattattatt aattccagca gaggcgtttt ctttctcaag ctcactagtt
    25801 gtatccgaac cccaacgcgg cgacgttaaa tcataatctc caatctgtct agctaaaact
    25861 gtagggagaa acaaactaga tgcaattgta actacgcaaa aaaggaatat atttttcttc
    25921 ttttcatgac atcgtcctct taagaagtga taaacaagat agttgattga tcaatttgat
    25981 acatattaca ttttcattat atcaataaaa gaaagcgttg tcaattattt tatttaaaat
    26041 attgtcatat tttaaataaa atggtaaaag agactcggta gcctcgtctc tctttatctt
    26101 actgacctaa ccttcttgcc aattttcttg gtcttcttta aagcgtttta gaagatcaag
    26161 gccctctggc gtgatgtaac cttcttcttg ggctagatgg ataagctcgc tatagtttga
    26221 aagcgtcaca agtttaacac cagcatctgt aaagttctta tctgcttttg gcaattggta
    26281 gctgaaaatc gctacaactc caagtacatc tgctccttct cgcttggctg ctgctacagc
    26341 ttcaagaact gaaccacccg ttgaaataag gtcttcaacc actaccattt tttgaccttg
    26401 agctacgcga ccttcgattt gattaccagc tccgtggtct tttggtttgc tacggatgta
    26461 ggcaaaaggc aagtccatct tatcagcaat aatggctccg tgtggaatcc ctgctgttgc
    26521 agttcctgca atcacttcta cttcaggaaa ggcttctttg atagcttcca caaaaccatt
    26581 ttcaattagg gtacgagttt ctggataggc tagtgtcaca cgattatcag tgtaaatcgg
    26641 tgacttgata ccagatgccc aagtgaaggg ttcctctggt ttgaggtaaa cggcttggat
    26701 tttcaagagg tggctagcga tatctttagc aagtgtcatg gtattctcct tttatttttc
    26761 taatctagtt ctttaattcc agtcctgtgt ccattcatcc ttgatggcat gataagctgc
    26821 aacaggatcc tcagcttggg taatgggacg tcctactacg atatagtcac tgccgatttg
    26881 ataggcatca gcaggtgtca tgactcgttt ttgatctcca actgcaacac cagctggacg
    26941 aatccctggt gtcagacaga taaaatctgg attggtagcc tgcttgatga cttgtacttc
    27001 ctgagccgag caaacaacac catccaagcc agcttcagct gtcttcttgg catagtgaat
    27061 cacagactct tgcagactgg tttggatatt ttgaaactcc tgcatctgag cttctgacgt
    27121 tgatgtgagc tgagttacag cgatcaattt agcttgactt ccaagacctt cacgcgcagc
    27181 cttcatcatc tctacaccac cagccgcatg aacattggtc atatccacac caagctgaga
    27241 taggatcttc atggctgact tgactgtatt aggaatgtca tgaagtttga gatccaaaaa
    27301 gacactatga cccaaacctt ttaagtagga cacaatctca ggccccgctg cgtaataaag
    27361 ctccatccct accttgagat aaaggctttc ttctgctggg aaaagagcta aaaattcctt
    27421 gaccgcctca aaactaggaa aatcaagagc aatgattgaa cgatgttctc gcataggttt
    27481 ctccttttac ctttactagt gagagagtct ggccaacaga agccacgaaa aaaggaacct
    27541 gccaacagca aggttccacg aaaaatgggt agtctccacc ctttcaccgt ctaaccttag
    27601 ctgcctctct ggactgcttt aaaggttttc tattattcta ttatttctac tagcacttgt
    27661 caagtaaaaa catggtcact aaagaactat aagagaaaag gtaaacctag cgacgcgatg
    27721 aacgctgggt cgtttggttt cgattgctct cttcctcttg ttttttctgt tcttcttctt
    27781 gttttttctc agcttccttg gcctcttgtt tggctttttc ctcagcttcc ataattaatt
    27841 tatccgccac agtgtaactg taaattccag cttccatgtc aatcacactc ggttctgaca
    27901 attgtggctt aatcttactg taatatggca gtttcttact catttcagat agaggaacca
    27961 agacttcgtc cgaatcattc atggtcaatc gaattaaatc ggatgtcacc ttgcttgggg
    28021 ctaattccac cttttggata gccgccttga gttctgggct aatttgagca agttctgaga
    28081 caaaaacctt gatttgttca ctatcattaa agagaactga taaataagtt tctggtaaac
    28141 tgttcagact cacagaacta gtctcaagct gaccactgga aagaatagga taatgatttt
    28201 caccagaaat atagtaggcc acaatatcat attccttgac cttaatagtg aacttagttg
    28261 gaaattgata gacaagttga gctgattcaa cccaatagtt agacttaatc tgcttttcat
    28321 attttgcctt gtctagcaga aggttaatcg tataatccga atcctgaatg cctgaagcct
    28381 gtcgaatatc atcagctgta gtttgcaccg ttccctcaac acgaatatct ttcatggtcg
    28441 cataaggact gagcaagtag gcagagacaa tcaataaaag cagacttgga aataaaatcg
    28501 tgaaggctcg caagatatgg ataccaggaa tctttgcttt ggctggtttt tcctttatag
    28561 cctttttagc aagcttttta tcctgttcct ccttctcttt agactctgat tcttctatct
    28621 cttctttttc tttgtcagcc tctgaggatg ccactttttc ttcagactct tccttagctg
    28681 attctgaatc ttcctggtct gtttcactct cctggtcctg tttatcctct gacttctcag
    28741 attcttctcc cattcgagct tgtctttcct tttccttctc ctcagctaga gccgcctctt
    28801 cttcagcctt cttttttaga tattcttggt ttcgtttctg ccattctgat aactctttca
    28861 attcttcgag ggtttctttg tcctcatttt tcttatcttt tgacatttac tttccttatg
    28921 ataaatcttt tttcaacaat tgataaaaat ctgctagaga tttcaattcc ttagaagctt
    28981 tcatcttagc ttggtaatct tccttgtgac ttagtaagtg agaaagcttc tcttccaaac
    29041 tatccaaggt caaatcgctt tcttgaaggt cttctgcata gccttttttt acaaagtaag
    29101 ctgcattttc aatctggtca ccacgactag cttcacgacc aagcggcaca atgacatgca
    29161 attttgctat cgccaagagc tcaaaaatcg tattggcacc acctcgtgtc acaacaatat
    29221 cagccaattc catcaagggt tgatagagat cggtcacata gtcaacacga aaaagatttt
    29281 gcctcaactc attcagacta gaatctccag ttagattgat aatattgtag cgctctgtta
    29341 gttctttctt atggtctgtc accaattggt taaagacacg agcgcctgca gaaccgccga
    29401 caaacaatac agttggcaat ttgggattaa agtgggtttg aatatccacc aattcatctg
    29461 gttctggagt gtttttgtcc gaaaccttgg tcaccgctcc cacatgctcg accttagcca
    29521 aactcgaagc ttgttcaaag gttgaataca tcttagtcgc aaatttatag gcgattttat
    29581 tggccaagcc catagacagg tcagattcgt gaataaagac aggcactcct gacacacgcg
    29641 cagcgataac aggcggtact gagacaaagc ccccctttga aaaaagggtc tgtggacgca
    29701 gtcgcaacat gataaagagc gattggacga ttccccagcc aactttgaag acgtccagca
    29761 tattttgcca agagaaatag cgacgcaatt tcccagtcgc aatagaatgg aaggtgacat
    29821 ccaaacctga cttaaggatt tcttggtgtt cgataccacg cttgtccccg atatagtgga
    29881 cttcccaacc atcttcgatg aacttgggca ttaacaaaag attgagggta acgtgtccaa
    29941 ccgtcccccc acctgtaaag acaatttttt tcatatttta ttcttttaac tccgctactg
    30001 tgtcgataaa gaggtcgcca cgtacttcaa agttagcata catatcccag ctggcattgg
    30061 caggactaag aagaaccaca tctccttgag tcgcaagttc ataggcctta cgggtcgcat
    30121 ctgcaatatc tgtcgcctcc acataagcga caccagcctt gtctgctgcc cgtttgacac
    30181 gttctgcaga ttgacccagg atgaccatct tcttgagtcc agtaatgtct ggcaccaatt
    30241 cgtcaaactc attgccacgg tccaaaccac ctgcaatcaa gacgaccttg ctgttgtcaa
    30301 atcctgataa ggctttttga gtagccaaga tattagttga tttactgtcg ttatagaatt
    30361 taacaccctt gatgtcatcc acaaactgga gacggtgttt gacaccaccg aaggctgaaa
    30421 gagtttcctt gatggtttga ttgtccacat cacgaagctt ggctacagca atagtcgcaa
    30481 gggcattttc cacattgtgg ctacctggaa caccgatttc attcgctgcc atgactactt
    30541 caccacggaa gtagagttga ccatcttcca gataagctcc atcaaccttt tcaagtgttg
    30601 aaaatggtac aacagtggct tctgtcttgg aagtcaagtc ttttgccaag tcttgattaa
    30661 agttcaagac aaggaaatca gctgctgtca tcttgttctg gatattccac ttggctgcta
    30721 catattccga aaatgaccca tggtagtcga tatgagttgg catgaggttg gtaataaccg
    30781 caatctctgg atggaattct tgaacaccca tgagttggaa agaagaaagt tccataacaa
    30841 gcgtgtcctt atctgatgct atttgagcaa cctgactagc tggatagccg atattccctg
    30901 ataaaagacc atgttgccca gcagcagtca aaacttcccc aatcatagtc gttgtggttg
    30961 tcttaccgtt cgatcctgtg ataccaataa tcggtgcttc tgaaatcaaa taagccaatt
    31021 ccacctcagt caagactgga attcccttgg ccaaagcctt ttcaatcatg ggattgttgt
    31081 aggggatacc tggatttttc accataaggg caaactcttc atccaagagt tccaaaggat
    31141 ggccacctgt aatgaccttg atcccttctt ccagcaaact ttgggcagct ggattgtcct
    31201 cgaaaggttt cccatcattt actgtcacaa tggcacctag cttgtccaac aaacgagctg
    31261 cagattcacc agacttggcc aagcctaaaa caaggacttt cttattttta aattgatcta
    31321 ttactttcat gtctcgaact ccatttctac tcctactatt ttaccatttt tatggaaata
    31381 aaaaagccac aaagtgtgtt tgtgactctt tcttctaact gaatcttacc atatcatcta
    31441 tgtgataaat cggtaactcg aatgacctga tccacttgct cccaaatcag aggattatgg
    31501 gtcgcaataa taatggtccg attcggattt tttaaagatt ctaggatgga aagtaattcc
    31561 tcagagtttt tggggtctaa ggaagcggtt ggttcatctg cgaggatcaa aggtggatcc
    31621 tttaaaatta tcttcgctag tgcaacacgt tgtgcttctc ctcctgataa ctcaaatata
    31681 ggttgcttca aatccaaata agagaggttt acacggttta gagcttgttt catcaaagag
    31741 attttctctt tttccttcaa ctttttacca actaaaccca gattgagatt ctctttgacg
    31801 gtttggcttt caattaagcc aaaatcttga aataagtatc ctaagtaatc tctaaagaaa
    31861 acagaaggct taatgtcctt aagagaagtg ccatcatata tgatttgccc tttgtcatat
    31921 ggctctaatc gtccaatcat attcaagagt gttgtcttac cacagccact tgtaccgatt
    31981 aaggcataaa ttttcccacc ttcaaaatga agattcgtat ctgaaaatag ctgacggctt
    32041 ccaaattttt tagatatatt ctttagttca atcatcctat tttcctttca taattgtcat
    32101 agaaacacga gattctttct gcgcttgacg gtaaagcgtc aaaactgcac taactagaaa
    32161 gaccaataaa gtgagcaagc caatcaccaa gtctcgactg cttaaaataa agagactagc
    32221 accaaataca aaactggcaa attggctaac catatactga gcatgtgttt caaaaaatcg
    32281 taaacctgaa attcgtttaa tcaagatatc tcggcggaat tgctcgaaat atagaagatt
    32341 gacagaataa aagagtaaca aggaactggc tattccaaca atagctccta agattaaagt
    32401 tgctgtttca gtttgaactt cattataacg agttagataa acacttcttc cttctttaag
    32461 ataggatact tgctcataaa ttccagcttt cttcaagagt tctagcccac tctcatatcc
    32521 tttgataaag agttgttttc cagcattgat agaccaacta gataaggata taaaactatc
    32581 acctgtagaa gtcggcgtga atacaactaa aatcggatca gtcaaatact gagtagatac
    32641 gggattctca ccgttattat aaacaaaccg cttttctccc attgaaagat aactaacgtg
    32701 cgctttcatc tcataatcca aaggagcact tgcctcctca ccagattttc cataataact
    32761 caatctttct tcaaaaactt tcttaagttc tgcttctcga gagcgcaaat gttctgggag
    32821 caagaggata aactcacctt tttggagatg ggctaacttc tgtttggtct cagcatctac
    32881 cacgaccttt tccttgtcca aataactggg actaacatag agcgtattag catctggact
    32941 ataggtatcc agtgtctctc cctgttcatt ttttccttgt ggattggcaa aatggagcag
    33001 attatccttt acataaagag cttgttcttc ttcgattgct tccttggcaa aggcatacca
    33061 cttgctctga ttttctgtat cttttcctct atcacctaag ccaaaggaaa tctggtaata
    33121 gtctgctctg tcctgccatg cttgttttga aatttcaagt tctttcaatc gttggtaaga
    33181 cgtcaaacct gtcttaacag cgtagcctac tgtaaaaaca gctactaact gacacaatag
    33241 ggttaaagcc atcaagcgtt taaggggtaa tcttccctta ataacgggaa ctaatgcttt
    33301 gtaactcaaa ctcattaggt aaaggagcat tagtaaaatt gaaatcgcca ataaaaacaa
    33361 cagatagaaa ctaatcccaa aaccataggt ggctaacaag ataggataaa acaaaccttg
    33421 actaaaaaga acgactcccc cacctaggaa ggaaaggagg gctgatagaa ggagccactt
    33481 gatatcagta gataaacccc aattattcac ccctaatcta aaaaccatcc agaatccttg
    33541 ccttagctta gatcctggat ggtttctttt ttcacccaat gggtgttttt tactagacaa
    33601 aaaagagttt cccctttatg gtataagtgt agaaaaaaac acaaaaagaa aggaaactca
    33661 tatgaacagt ttaccaaatc atcacttcca aaacaagtct ttttaccaac tatctttcga
    33721 tggaggtcat ttaacccagt atggtggtct tatctttttt caggaacttt tttcccagtt
    33781 gaaactaaaa gagcggattt ctaagtattt agtaacgaat gaccaacgcc gctactgtcg
    33841 ttattcggat tcagatatcc ttgtccagtt cctctttcaa ctgttaacag gctatggaac
    33901 ggactatgct tgtaaagaat tgtcagctga tgtctacttt ccaaaattgt tggaaggagg
    33961 gcagcttgct tcacagccaa ccttatcccg ttttctttcc agaactgacg aggaaacagt
    34021 ccatagtttg cgatgcctca accttgaatt ggtcgaattc tttttacagt ttcaccagct
    34081 aaaccaactc attgtagata tcgattctac ccatttcaca acttatggca agcaagaagg
    34141 tgttgcttat aacgcccact atcgtgctca tggctatcat cctctttatg ctttcgaggg
    34201 gaagacaggt tattgtttca atgcccagct tcgtcctggt aatcgttatt gttctgaaga
    34261 ggcagacagc tttatcacac ctgttttaga acggtttaat caacttctct ttcgaatgga
    34321 tagtggcttt gcgaccccaa aattatacga tttaattgaa aaaacagggc aatactacct
    34381 cataaaactc aagaaaaata ctgttctgag ccgtcttgga gacctttccc tcccttgccc
    34441 acaggatgag aacttaacca tcttgcccca ctccgcctac tcagaaactc tctatcaagc
    34501 aggatcttgg tcgcacaagc gtcgtgtctg ccagttctct gaacgaaaag aaggaaactt
    34561 gttctacgat gttatttctc tcgttacaaa tatgacgagt ggaacaagcc aagaccagtt
    34621 tcagctttat cgtggacgtg gtcaagccga gaatttcatc aaggagatga aggagggatt
    34681 ttttggcgat aaaacggata gttcaacctt aatcaaaaac gaagttcgta tgatgatgag
    34741 ctgtatcgcc tacaatctct atcttttttt caaacatcta gctggaggtg acttccaaac
    34801 tttaacaatc aaacgcttcc gccatctttt tcttcacgtg gtgggaaaat gtgttcgaac
    34861 aggacgcaag cagctcctca aattgtctag tctctatgcc tattccgaat tgttttcagc
    34921 actttattct aggattagaa aagtcaacct gaatcttcct gttccttatg aaccacctgg
    34981 aagaaaagcg tcgttaatga tgcattaaag aacagtcgag atgaaaaaat cgtgtgacgc
    35041 accaagggag gagtctgccc ttttgaggaa atctagcgag gaaaaacgat actggaacag
    35101 cagaaagtaa aactgacctc atgaggagga agaaagtggc tcatgaggtc aggggttttg
    35161 taagttacat ctagttgaga gaggtatgaa tgatttggga taaagaatcc cccatgatgg
    35221 ataagagagt ctgaccagaa aagagtttta tacctgctgc tctcatttcc ttaatccgag
    35281 tgataatcac taaagcaaag aaagataagc caaatattgc taaactaatt aaaataaggg
    35341 gatttagtaa tattcgaaaa gcaagaaaat agggcggtat ctttcggtca gcacttgctt
    35401 tataacccaa atctcctaat ttatcggcaa gcttttcttt cgtcaaggag cctgacaaaa
    35461 ggagataact atttagcgga tcactacgtt cacgactttc ttggctagct tcttggaatt
    35521 cttttggtaa agttccctga ccataagttg cataagtaaa gtgagtcgtc ccatccttac
    35581 tcggctctac aattcttcta gctattaaac tctgttctga gtttgcaaaa ttctccaatt
    35641 cctgttcaaa tacctcacgc gtcggttcct gagtatcttt tttgacacga agtaaagaaa
    35701 cggaatcata gcttgcatat aaatattgtg gcgcacgtaa gacaataatc caagcaagga
    35761 agaagctgag aaaaaaagtt gataataata tgaatagttt cttcatagta gactccttgt
    35821 aaacaaaatt ccccctgtaa tttcttacaa ggggaacgat ttaaatcaat gaacgattag
    35881 tcataatcac agtaaaatgc tacttgttct ccccatttag tccaaatcca tgcataggag
    35941 gtttttccag caggagcttc tcctttatca gaatgaccat cccatctgct cacgatggat
    36001 gaataatgat attttttacc atgatagtaa tttgaaaaag cctaaccacc tcctgaacct
    36061 tctccatatg tccatactcc tccatctgga tattatacag cagctgatgc agctcccaat
    36121 aatgtaaaac ttgaaataag agctagagca agtaatctat gttttttcgt tttcatttta
    36181 ttttttcttt caaaaaaatc acaccttgag caacaatgca acaaaataaa tcctcctctc
    36241 tcttttattg aaaccgcttt cttgtgtgat aagaataaca tttttattat ttgttgtcaa
    36301 ggaaaaaatc gaatttttta gatgttttac tatattatct ctatgaataa tattatatag
    36361 tagttttatt tcaaaataat atgcaaccag tactaaccaa atataaaata gatgccatta
    36421 acgaatttta ttcaagtttt tcccattcat actatacaag caaaagagat ggtgttaact
    36481 aaaaagcaat tcaaactatt ataaaattcc tagcaaaaag agagccgaaa ctctcttttt
    36541 tatcttcttt tacttttttt gactggcatg agtgtgatgt ctctaacact aaagtaagct
    36601 aggatcaaca tggctattgc taggaatatt tctgttggta attgaaaaat tttcagaaaa
    36661 gatagaacca ataaaatcaa gagtgccact aaaatacata ccatagcgac gatattgact
    36721 gtccctttaa tgctttctgg tgtcgcaaat acatagagta ggagcagtaa aattcctagg
    36781 actaaataga ccatctttct ctctttctag ctcttattca gctgattttt tcttcttatt
    36841 agctttctca cgctctgctt tgttaaggat ttgtttacgc aaacggatag actcaggcgt
    36901 tacttccatg tactcatcgt cgttcaagaa ctcaagagac tcttcaagtg tcaagatacg
    36961 aggcgtcttg ataacagctg tttggtcctt agtagctgaa cgaacgttgg tcatttgttt
    37021 tgccttcgtg atgttaactg tcaagtcatt ttcacgagag ttttcgccga tgatcattcc
    37081 ttcataaacc tcagtacctg ggttgacaaa gatcgtacca cgttcttcga tagacatgat
    37141 tgagtaagtt gtagccttac cagcatcgat agaaacaagg gcaccacggt gacgtccacc
    37201 aatttcccct ggaatcaatg gcaagtattg gtcgaaggta tggttcatga taccgtaacc
    37261 acgagtcatt gacaagaact cagttgagta tccaatcaaa ccacgcgctg gaacaaggaa
    37321 gaccaaacga gtttgaccat taccagttga aatcatatcc aacatttcac ctttacgttc
    37381 agaaaggctt tggataacag acccttggta ttcttctgga gtgtcgattt gtacacgttc
    37441 aaatggttca catttaacac cgtcgatttc ttttacgata acttctggac gagatacttg
    37501 aagttcatag ccctcacgac gcattgtttc gataaggatt gacaagtgca attctccacg
    37561 tcctgaaaca gtccatttat ctggtgaatc agttgggtca acacgaaggg aaacgtctgt
    37621 ttgcaattct gcctgcaagc gttcttccac cttacgagaa gttacccatt taccttcttt
    37681 accagcaaat ggtgagttgt tgaccaagaa agtcatttga agagttggct catcgatgtg
    37741 taggattgga agagcttcta ctgcatctgt cggagtgatg gtttcaccga caaagatgtc
    37801 ttccatacct gaaacggcaa tcaagtcacc cgctttggct tcttggattt cacgacgttc
    37861 caaaccaaag aaaccgaaga gttttgtaac acggaagttt ttagttgtac cgtcaagttt
    37921 agaaagggta acttggtccc caaccttaac tgtaccacgg aagacacgac cgataccgat
    37981 acgtccaacg aagtcattgt agtccaaaag tgacacttgg aactgcaaag gctcatctga
    38041 gttatctact ggagctggga tatggtcgat aatcgtgtca aagattggtg ccatagtcgc
    38101 ttcttggtca gctggatcat ctgacaatga agaagttccg ttgatcgctg aagcataaac
    38161 cactgggaaa tcaagctggt cgtcatctgc accaagctcg atgaaaagtt ccaagacttc
    38221 atccactact tctgctggac gagctgatgg cttatcgatt ttgttaacaa ccacgattgg
    38281 gacaaggtct tgttccaagg cttttttcaa tacgaaacga gtttgtggca tggttccttc
    38341 ataggcatct acgaccaaga caacaccgtc aaccattttc atgatacgct caacttctcc
    38401 accaaagtcc gcgtgtcctg gtgtgtccat aatgttgata cgagttccgt tgtaagcaac
    38461 ggcagtattt ttagcaagga tggtgattcc acgctctttt tcgatatcgt ttgagtccat
    38521 agcacgctct gccaattcag tacgtgcatc aagcgtttct gattgtttca ataattcgtc
    38581 aaccagggtt gttttaccgt ggtcaacgtg ggcgataatc gcaatgttac ggatatcttc
    38641 tcttaatttt gtcatgattt cctctataat attcaaaatt tattttctaa ctgaacgatt
    38701 ataccataat ttcaaataaa taacataact caagcaagtg taaatgtttt cactccgctt
    38761 ttcttttcac gtcaagcctt ttcaaagcaa gcgacttatg ataagatagg cacagtatgc
    38821 gtttagataa tttattagcc caagaaaaag ttagccgaaa ggccatgaag caagcactcc
    38881 tcagagggga aattctagtc gatggttgcc cagcccgatc cctagctcaa aatatcgata
    38941 caggactaca agaactcctt tttcaggatc gaatcattca aggctatgaa cacacctatc
    39001 ttatgcttca taaacctgct ggtgtcgtta cagccaacaa agacaaggaa cttccgaccg
    39061 tcatggacct gcttccatct gacatccagt ctgacaagct ctatgccgtt ggccgactgg
    39121 accgagatac aacgggactc ctcctcttga ccgataacgg tcccttgggc tttcagctcc
    39181 tccatcccca atatcatgtc gataagactt accaagtcca ggttaatgga cttctaacac
    39241 ctgaccatat ccaagccttt caaaagggaa ttgtcttttt agatggtact gtctgtaaac
    39301 ccgcaaaact agagattcta tctgcaagtc cctccctcag tcaagcctct atcaccattt
    39361 cagaaggaaa atttcatcaa atcaagaaaa tgttcctctc ggttggtgtt aaggtgacta
    39421 gcctcaaaag aatccaattt ggggacttca cattgaaccc agatttagca gaaggtaact
    39481 accgcccttt gaaccaaaaa gagttacaaa tcattaaaaa ctatttagag atgagtcgat
    39541 aaaacaaaaa aagctttaaa actaaagctt ttttctttta tttaccgaaa aattaaggcg
    39601 attgctacaa tccagttaac tacagaaatc acaattccta agatattaag aatcttttct
    39661 attttatagt ctaattgtga ctctttttgg tatgaaatag ccaagaccaa tcctatgata
    39721 cccaaaatca ggcctacaat tggaaataac aaaccaagaa taatcgacaa gatacccaca
    39781 aaaagtggat ttttcttctt ttctttcatg ttctaagaac tccttaaatt ttatacaaat
    39841 taattatact ataaaacaat atcttcatcc tatcattcga ctaatttgga aataaggtta
    39901 gctagtcttc actttccctt tccaagaatc caagccataa gaaaggatat aaatctcaga
    39961 aaaaccttgt tttttcaagt aaagagctgc atttgtaact cgttgcgcac gttggttttc
    40021 gtagagaagg acaggtttat ctttacgaag ggctgcaaga ctagttttca actgacttga
    40081 aggaatattg cgtgcaccaa ggatatgttt tctgtggaat tctgctgggt cgcgcaaatc
    40141 aatcaattga cccgtacgaa tcaaggcttc aaactcctca ttgtccacaa ttttagccgc
    40201 acggcgaata cgaagatagt taaagcccat ccacgccaac attgctagta taagtgccca
    40261 caaaatccaa gtaaccatta gttcttttct ccatttttct caatataatc caattctacc
    40321 ttgtgctctc tgcgaagaac tgcttctgcc tctagatagt ctaatttatc catcaaccct
    40381 gcatcgtaaa tccgagatag ttccaacttc atcagttcaa tatcatataa tcgttttccc
    40441 atgtaaacaa taataccaaa tcgtttgagg aattgctgca catcatagaa tgttttcata
    40501 agactcattc tagcaaaatt ttgtgttttt ttcaagaaga gactcacaca atgctcctta
    40561 ttttcctatc ttctttagcg attctaaggc aagtatggta caataaaaac atgagaattc
    40621 aacaattaca ttatattatc aaaatcgtcg aaactggctc catgaatgag gcagccaagc
    40681 aactctttat cactcagcca agtctctcca atgcagtgcg agatttggaa aatgaaatgg
    40741 gcattgagat ctttatccgc aatcccaagg gaatcacctt gacccgtgat gggatggagt
    40801 ttctctctta tgcccgtcag gttgtcgagc agacccagct tctggaggaa cgctataaaa
    40861 atcctgtcgc ccaccgcgaa ctctttagcg tttcgtctca acactatgcc tttgtggtca
    40921 atgcctttgt ctctttgctc aagaaaagcg atatggagaa atacgaactc ttccttcgtg
    40981 aaactcggac ttgggagatt atcgacgacg tcaagaactt ccgcagtgag gtcggggtcc
    41041 tcttcttaaa cagttacaac cgtgatgttt taaccaagat gctggatgac aatcacctgc
    41101 tagcccacca tctcttcaca gcgcaaccgc atatctttgt cagcaagacc aaccctctgg
    41161 caaagaaaga caaggtgaaa ctgtctgatt tggagaattt cccttacctc agctatgacc
    41221 aagggacgca caactccttc tacttttcag aagagattct ttctcaagaa caccacaaga
    41281 aatccattgt ggtcagtgac cgtgccaccc tctttaatct cttgattggt ttggatggtt
    41341 ataccattgc gacagggatt ttgaacagca acctaaacgg agacaatatc gtttctatcc
    41401 cactggatat tgatgacccg attgagctgg tctatatcca gcatgagaaa accagcctat
    41461 ctaagatggg cgaacgcttt atcgactatc tactagaaga agttcagttt gatagttgag
    41521 aaatgataag aaccaatatg taggctagca acaacctgca cattggttct ttttacttat
    41581 aattaaaagt ttcccctgcc aacttatcag ctagcttggg aaagagagta taaaacttat
    41641 gggctaggtt caacaaaatc gggagattga gttctcgttt atttttgcct ataatcttga
    41701 caatcttttt agccactgca tctgcctcta agaggaagcg gtcaaccgat ttaagataag
    41761 ttccatctgg gtcagcttgg tcaaaaaatc ctgttcggat tggacctgga ttgactgttg
    41821 tcacatagac tccatagggc ataagttcga gtcgcagagc atttgaaaaa ccaatagccg
    41881 caaacttggt cgctgagtaa agactagact tgccagtagc tattagacct gccatgctga
    41941 cgatgttgat gatatgccct ttgctgcttt ccttcatacg agccgcaagg tgacgagaca
    42001 gattcatcag ggcaaaggta ttgacctcaa acatctggtg aatatcttta tcagcaatct
    42061 ggtcaaatcc ctcaaaaatc ccgtaaccag cgttgttaat caagacatca atcttgccat
    42121 agcggagata aagatcagtt accagagctt ctagggctga atcgtcggta atatcaattt
    42181 caatcaattc tgcatgggaa taatttccgt agagttgggc taatttttcc ttatttctac
    42241 caagcaagat gagttgatca ttgggcagga gtttgaccat ttcttgagct agaccaccgc
    42301 tagctccggt aatgagaata gtaggcatac ttatcctttc tgtgactgct agatttccac
    42361 ttcttccaag tctttgacca catggacatt ttcaaaaatt gtggcagcgt ctttcttgag
    42421 tttgcttata tcttttgaga ggaaacgggc actgatatgg ttgagtagga ggcgtttggc
    42481 acctgcttct accgctactt gtgcagcttg catattagtt gagtgaccat ggttacgagc
    42541 aattttttca tcacccttgc cataagtgga ctcatgaact aggacatctg cattgacagc
    42601 cagacgcaca ctggcatccg tttttcgagt gtctcctaaa atagtgataa tcttacctgg
    42661 acgtggcgct gagatatagt ctgctgcctt gatttcagtt ccgtcttcca aaacaagatc
    42721 ctggccgttt ttgattttac caaaaagcgg gccgaacgga acaccagcag ccttgagttt
    42781 tttagcatcc agcgtccctt ctagatcctt ttgcatgaca cgatagccaa cacagaaaat
    42841 agtgtggtcc agctcctctg catacacagt gaatttatcg gtttcaagaa ttttacccag
    42901 agaatcttgg tcaaactcat ggaaatgaat gcggtagggc agacgagaac ctgacacacg
    42961 aaggctggtt aagacaaatg acttgattcc ttgaggtccg tagatttcca aatctgtctg
    43021 ctcttcattg gcctgaaagg cacggctaga aaggaaacct ggcaaaccaa aaatgtggtc
    43081 tccatgcaga tgggtaataa agattttgct gaccttacgt ggtcgaattg tggtttccag
    43141 aatgcgattt tgcgtacctt ctccacagtc aaagagccaa acttcgttaa tctcatccaa
    43201 aagtttcagg gcgagacttg aaacgttgcg ggctttagag ggctgaccag cccccgttcc
    43261 taaaaattga atatccattc gatactttct aattaatcaa tatataacat ggctgtgcgg
    43321 ttttccgatc ggaaatagcg tttgccagaa aaagcagcag cttcttgcaa taaatcctct
    43381 tggctgtagc ctttgagacg ttttcgacca tcagccaatc tttccaaatc agtcaaagct
    43441 gtgagacttt ctaggctgac aacttcctcg tcctcgacag gcttcatgta aatcttacca
    43501 gactcttcaa agactaattg atgggggaaa atttgcgcaa tttcaaagag caagtcatcc
    43561 gagattttct cctcattttc agagaaaatc cgaccaaagc cgtcactctc ataacaaaaa
    43621 ccaaaggatt taccagacag attaagccga ataaaagact tattttctag ggtgaaactt
    43681 ggctcagtat tgtaaagatt cagttcctga ctgagttctg caaaataatc cgtcgcagcc
    43741 tgaggacttt ttttctgata gagttctgca aagtaggcat taacaacact tggcggaggt
    43801 gtaataagtg ttaactgctc ctgctctgtc ttaccagcta gaagctgatc cagatagacc
    43861 ttgtccagac ttgtataacc tccatacttt agagccaaag ttttaatatc agtcataaaa
    43921 ttcttctaac ctccatttat ttttctcgga aatgtagcct gtaatcactt cgccgtcttc
    43981 ctgataatca cgttcttcca gaattgcaac actctctaaa tcatgaatct tgtaggactt
    44041 tgaaaaaggc actcgcaggg taaatgcttc aaaaatttcc ttaatcttat ctagcaataa
    44101 tgcttgcaag ttttcacgac tgtcctcaga cttggcagaa atgagggtat atggcgtttg
    44161 agtaggcgtg aaatcctcca ccaaatccgc tttattataa agcgtcaagt gaggaatatc
    44221 ttccatgtcc aggtctttca tgatggagag aaccgttttt tcatgctcct cgtggtaagg
    44281 attgctagca tcgataacat gaaccagaag gtccacatgc ttgctttctt ccaaggttga
    44341 cttgaaactg gacaccaact ctgtcggcaa atcttggata aagccaacgg tatctgtcaa
    44401 agttacttgg agattgcctc ctagatgaat actcttggtt gtcgcatcca gagtcgcaaa
    44461 gagctcatct gcttcatact gggtcttact ggtcaagatg ttcatgatag ttgatttccc
    44521 agcattggta taaccaatca aaccaatctt aaaggtgcta gactccaaac gtttttctct
    44581 gacagtcgca cgatttttct caaccacctt aagctggcgc tcgatatccg tgatttgatt
    44641 gcgaacgcta cgacggttca gctccagttg gctttcacca ggaccacggg aaccaattcc
    44701 ccctgcctga cggctgagca taatcccctg accaaccaag cgaggcaaga ggtatttgag
    44761 ttgggctagg tggacttgga gcttcccttc atggcttcga gcccgcatgg caaagatatc
    44821 caaaatcaac tgcatacggt caatgacctt aacaccgaga acttcctcta gattgacatt
    44881 ctgccttggg gtcagacggt tgttgacgat gacagtagtg atttcttctg catccaccat
    44941 aagcgcaatc tcttccaact taccagagcc gacgaaggtc ttggaatcat atttttcacg
    45001 tttttgtctg tagctatcta caacgactgc ccctgccgtt ttcgctaaac tagccaattc
    45061 ttccatggag aggtcaaaac tgtccatacc ctgcaattcc acaccaatca gcaggacccg
    45121 ctcctctttt ttctccgttt caatcatcta aaaactcctc tatctggctt aaaatgcggt
    45181 cttgtacacc agattctcca atctgataaa aggtgacctg catgcgatta cggaaccagg
    45241 tcagctgacg cttggcaaaa cgacgagtag cctgtttgag actctcacga gcttcctcca
    45301 aggtctgctc tctacggaaa taaggaaaga gttccttata gccaattcct ttagcagcct
    45361 gtacattagg ggaatggtca aacagccact tggcctcatc caaaagccca gcctcaaaca
    45421 tcaaatccac tcgatggttg atacgctcat aaagttgact acgttcatca tccaagcaga
    45481 taatcagcgg ttcatacaag gtctcttgat tttccaaatc ctgaccaaaa tgggcaattt
    45541 ctaaggcacg catagcacga cgacgattaa actggggaat ctcaaggcct gcttgctcca
    45601 ccaaatgggc taattcctca tctgaatatg gctccaaact agctcgataa gctaaaatct
    45661 cctcatgagg agtctcccca cctaggtggt aaccttctag caagctctgg atataaagtc
    45721 cagtcccacc ggcgataatg gctagcttgc cacggctgtg aatatcctca atagtcatct
    45781 tagcttctga aacaaaatca aaagccgagt aagactcggt tatctctcta acatcgatta
    45841 aatgatgaag aacagctgcc tgctcttctg gactagcctt ggccgtccca atatcaagtc
    45901 ctcgatagac ttgctggcta tctccactaa ccacttcgcc attaaaacgc tttgcaactt
    45961 caatagctag agccgtcttt ccaacagcag tcggtccaac aatcacaatt atttttgttt
    46021 tcatcttttt tccttgaaaa attcccattt tttcgttact attattataa cacaaaaagg
    46081 tcagtcagaa aaatgtgacc tcttgaggag gctggctgat tgagaatata aaggaggaag
    46141 actcatggct aaaggattcg ctaaaggtct tgtaacaggt gtcgcaggaa ctgtcgctgc
    46201 cgttgcaggt gcagtatacg catttaaaaa gaaagtaatc gaaccagaag agcaaaaagc
    46261 agctttcatc gaagaaaacc gtaaaaaagc agctcgtcgc cgcgtatcac gttaagaaac
    46321 aaaagaagtt gggattattc tcaacttctt ttttctattc ttttaaatag ctaggtcaaa
    46381 cttcaactgt ggcttaacag ggtcataatc caccaactca aaatcttctg ctttgatatc
    46441 aaagaaatta gtcccatcag gaacatttaa aaccaagcgt ggttggcagt ttgacggctc
    46501 ccgacggagc aattcctgag cttgttcaaa ttgattatca tagatatgga ggttgttgat
    46561 gaagtagaag aacttcccaa ccttccagcc aaaatgtttg gcaatcatca tctgcaaagc
    46621 cacatactgc atagcgttga tgtggtgggc caccagcata tcattggagc gctgggtcaa
    46681 ggtcgcatcc agatagattt ccccatcaac acgccgaaca tcaaacatgg tctgaaaggc
    46741 gcacgggagc agcccatctg tttcttcgaa agcttggtaa tcccagagag aaataatatt
    46801 gcggcggttc caaggattgg ttttcaactg tttgagaagc ttattgataa tgtcgtgttt
    46861 cttaacaacg gcaccatagc gctcaccaat ggttcccgtg tctccaactt cccagtcatt
    46921 ccagtagtga acattgtact tgtcattaag cacttctaag ctatttgact ggtcttggta
    46981 aatccagaga acttctttga tggcggattt gattgcaatg ggacgcaagg ttgtgatagg
    47041 aaattctcct ttagataagt cgtactcgga aaaggcacca gttacatact tggaattagc
    47101 aacagtccca tccttgtact taggacgagc ctgctctgag aaaacacctt cctttagaat
    47161 gcgttcaata ttctctttaa aaatcgtatc tgcttttgtc atttactctc acctcattca
    47221 ttgtcctaac tagtatagca taaaaaataa aagaggaaca ttactaactc taggttagca
    47281 ttttcctctc tcattatctt attgcaatac aagtgatgct gctccgataa ctccagcgtc
    47341 atttcctaga gttgcaagag ctaatttagt agatgtgcgt acttgtggga aagtattttc
    47401 gtcatagact ttttgaacac cttgtagaag gaattctccc gcagctgaca caccaccacc
    47461 gatgacgatt gttgatgggt ttaggattga accaatgtta gcacaagcga ttcccaagta
    47521 acgtgagaag ttacggtaaa caatcaaagc aaggtcgtct ccttcttttg cgagatcaaa
    47581 gacagtctta gcagttactt cttctccgtt atcaatcaag cgtttcaagg ctgcatcgcc
    47641 ttcgtattca tcggcatagc gacgagtcaa gttgacaatt cctgttgcag aagcgactgt
    47701 ctcaagacag cctttcttac cgcaagtaca tgagattggc tggtcaaagt caacagtgat
    47761 gtgaccaagc tcacctgctg caccagcaac accgtgaagc aatttgcctt ctgcgacgat
    47821 accgccacca acaccagtac cgagtgtcat aaagacaaca tctggttggt tatcaccagc
    47881 acccatccag cgctcaccaa gagctgctac gttggcatca ttatcgatga aaaatggaat
    47941 gcccaaagat ttttcaatct tttgtttgat tggttgaagg gttttccagt tcaagttgta
    48001 ggcaccgata acagtccctt tgtcacggtc aaccacacct ggtgatccca ttccaatgcc
    48061 ttggaagtcc gctgctgcca atccaagcaa gtccaaacga tgttgaatag actcaatcat
    48121 atcatcaacg atatgacttc cctcatccaa aatgttggtc ttgattgacc attttccttg
    48181 gatttctcct gctgttgtta agattgcaaa tttgatagaa gttccaccaa ggtcaatccc
    48241 aataatcttt tgactcatca tattctcctt tttcattgtg tagtaattga aaatgcttac
    48301 agtactagta tatcaaaatc cattcactta tgcaaaggtt tgcgtaaatg aattataagg
    48361 aattttttcg cctaccagta tctgttaatc atctaaatga tcaatggcat attgagctgc
    48421 atcatttgaa aatttatcaa aatcagaagt taattgtcta tacatacgtt tttttgacat
    48481 atggaataac gaattataac tttttgcttt tcctaaagca gcagaatatt cactattgct
    48541 atcattacta gaagaagctg tacttgcttg accttccttc caaactccgt cagcaccaac
    48601 ataataacgt ccaccatcaa cccattcatt gacagccatt ttaccatccg attttagata
    48661 gtaatttcct tgccatgtac tgtaagcata agaaccatct gatttcaagt aataccaagc
    48721 ttgataggtg gcatcataaa cccattcacc ttgtgccatt ttaccgtttg atttaaggta
    48781 ataagctcct tgccatgcat tgcgagcata agaaccatct gatttcaagt aataccatgc
    48841 ttggtaagaa gaatcataaa cccactcacc ttgtgccatt ttaccgtttg atttaaggta
    48901 ataagctcct tgccatgcat ttttcactag atttccattt ccatcaaaat agtaccaaga
    48961 accgtcctgc ttaacccaac cacttgctgt ggatgaagtt gtatcagttt gagttgtagc
    49021 cgcttgtttt gctttaaaag tacccttagg agcatttttc aattcgcaag ccacaccatc
    49081 atgatcgcgg tctaacttgg cagaataacc aggttctccc tcatgaagat ccgaatatcc
    49141 attagcccaa gcttccttac aactcgaaaa atgaatgttt tcctctgcta acacaggttg
    49201 tgaaaacaag gctaaaattg gcaacgtcac cagactcatt tttaaaaata gacgtttatt
    49261 catttctttc tcccataatt atgatatcga tttcaatatt attttatcaa acttatttca
    49321 gcaattcaag gaaacttctg gtcttttcta caaactcctt tggttttgcc ttattcaaga
    49381 catgagggcc atctgagata atctgaaatt gggattctga tattagttta tgaagacttc
    49441 tcatagaact aagattcggt ttatctttga taccacaaat tagtaaggtt ggataagggc
    49501 aagttcctgc tatatccgtt aaatcaagtg tcttcaactc ctcagaaact ccgaccataa
    49561 gagccttgtc tgctccctgt ttttcaaata ctcttttggg aagtagttta aaaatcagca
    49621 actgaagata aaataggata ttccctgcta atttaagcgg gcatcctgac agaatcaaag
    49681 ctcgaagatt tggtaaatcg taactggaaa gttctagtgc cagggcagca cctaaggaca
    49741 atccaatcaa aacaaaaggt tctgtctctt gagctaggta ctgataaact cgctccttag
    49801 cttgttgata gttactaact ccagaaggaa ataactcgat agcctcagaa ggataatctg
    49861 tcagtagatt ccgaacttct ttccaagact ctgctgactg ccctaaccca tgcaaaaata
    49921 tcagtttcat ctagttctcc tcaaggctta gttcatacaa gcctctcact gcattacagc
    49981 cgtaaatagc ttctgcttgg gctaaatctg ccaaggtcaa gactttctct tctacctgtc
    50041 ctgtttctag caaatactga cggtaaattc ctggcaagat tccaagtcgg ataggcggtg
    50101 tgtagagttt tccagcgatt ttcagaacca aatttcctat agaggtttca agcagttctc
    50161 ctgacttatt gtggtaaatc ttctcttgtt ctcctaggct caaatgcggt cggtgagtgg
    50221 ttttaaagta ggtaaaggat tgattcaaag cagcttcctg aaggcagact tgggcctgac
    50281 aaaagcttgt actgagaggg gttaatactt gacgattgac ttctatctct ccagatttgc
    50341 taaggctgat tcgcaagcgg taatcttgat tagcttcaca atcctgacac tcttcctcaa
    50401 tcttgtgtcc caagtcttct gcatcaaaag gaaaggcaaa ataacgacta gcttttctca
    50461 gtctttccag atgtttatct tcaaacagca ggttcttctg gctgatttcc cctgtcgtaa
    50521 tcagttggaa gcgagcttgt ttacgataaa gaactgctgc cttttgatga acctctcggt
    50581 attcagattc ccatgtgcta tcccaagtaa tccctccgcc aactccataa atagcttgac
    50641 ctttgtgaag ttgaatggta cgaatggcca cattaaaaat ccgtcgtcca tttggaagca
    50701 agagaccaat cgttccacag tagactccac gcggttgagg ctccaagtcc ttgataatct
    50761 ccattgtcgc aattttcggt gcacccgtta tggaaccaca aggaaagagt gagcggaaga
    50821 ttttaacaag gtccacatcc tctcgcaact gactcttgat ggtcgaagtc atctgccaaa
    50881 cagttgaata ctgctctacc tggcacagac gctccacgtg ctcgctccca acttcagaaa
    50941 tacggttcat atcattgcgc aagagatcca caatcatcat attttcagag cgatttttgg
    51001 gatcctgttc caaccaactg gcctgttcaa gatcttcttg gtcagttacc ccacgctgag
    51061 tcgtcccctt cattggtcgt gttgtcaact cgcgatcatt ttgctcaaaa aagagctctg
    51121 ggctcatgga aatcactgcc atctcgtcat gttccacata ggcattgtag cccgcttcct
    51181 gctctaccac catacgattg tagatggcaa aaggattggc acttaacttt tgcttgagtt
    51241 ggacggtgta gttgacctga taggtgtctc cctgcctcaa gtgatggtgt atctgggcaa
    51301 tggccttttc atagttctct gcagacgtta cttcctgcca atttgagggc aaatcaatat
    51361 cctcataagt cagaggaata ggggaggtct ctaccctatc atgaacagta aagtaaagca
    51421 ggtactctcc cagtagggga tccttgtgaa ctgctaattt ttcctcaaaa gcaggtgcag
    51481 cctcgtagct gacatacccc accacataat aaccttgctc ttggtagctt tccacttgtg
    51541 ccagcaaatc tgccacttct tctacatttc tcgttttcaa ctctttaata ggctggataa
    51601 aggtatatct ctcccccaaa gtcctaaaat caatcactgt ttttctatgc ataccttaag
    51661 tatagcataa aataagaaaa ccctcatccg caaagcagat gagagatttc aattatttaa
    51721 agattgaagt tttaaagcta tttgtttgtt gaagaagttt cttataaact ttttctttta
    51781 cttgcacaag tttaccatta actttattag taaccatatc ttcttcaaga gctttggcaa
    51841 ataatgattt taattcatca tagttatgaa tggtctcacc atcaatagta aaaggagtaa
    51901 aaccagcgtt ggctttttct aacaattctt tataatattc tttcttaaaa tcagcaaacg
    51961 attggaatct gccgtcagat attttttgta taatatattg atctccaaat tgtttccctt
    52021 ctttattagc ttgagatttt aatttatctg aagcatatcc taagaatcct ttatcatagc
    52081 cataatatcc ccagagtcta aatgcattat tcttaaatgt aacagcaccg ggtgcaccct
    52141 cacttgtgtt acctgcatag atactattca tcattttaat tcctacatag gcaatacctg
    52201 gatcaaatac ttctggctta tatatattat tattcatcat acgattagtc atcagattat
    52261 tatcaactaa gtcattaaca ctgtttaatg ttattccttt ccaatcatca gaactcatat
    52321 ttcgaacctt gtcatattga tcttttgacc ctacagtgcg ttcaatagga tcaactttct
    52381 taaaccacag ttgatttaat ttatcatcat gtttactaat gactgcatca ccttcaacat
    52441 aatcaagaag agacaaggta tctatataac ctttcatata attatcaatg tcttctcttg
    52501 ttttaagagt cttcggatcg gtaatatacc actgatttcc atcatttgga cgatagaaag
    52561 tcatattaat tcccaaagca ccgtattcat caaaccatgt acttggtact ggtgtttgta
    52621 acattccttg tgcataggct tctgcatgag tccctgagcg acgtccatat cctcctaaat
    52681 agattgcacg atcattaaca tgagtagttt catgtgtata aacagagatt ccaaactcat
    52741 caatcatact taatgcaata taatttactt ctgttcgcgt atccaaagga ttatcccaaa
    52801 taactgcata agcacctgtt ccattgttac cataatactt accaataggt ccaaacaact
    52861 ctctcaatgg ggcatagtct tctttattat tcctcttacc atacttatca ggccatccac
    52921 caggtgcttg ataaccttcc caaagaggag ttactgtatt tttgactagc atattcttaa
    52981 ccttatctaa agataatcta taccaaaaat caaagtaatt tcgataactg tccgctgctt
    53041 tttcgatctg attttttatt ccatcgaagg agctatgccc taacttttct gctgttccaa
    53101 cagccattgc actataattc gagattaaat acacatgtga tttatttaga tttaataatg
    53161 ggagtatcat cttccgatga gtagcagatt gtaaattatc ccaaacttta tatttcgccg
    53221 ctttaatttc atcgacttcc gaagcacgct ccgctatata gacattccct tctgtagctt
    53281 tcttaaacca atcataaata tttacatctg cagtaaatag tcgacgatta taatttaaaa
    53341 agtttaccaa attttctgat aaggttgtct tagaaataat ctcgctgaaa gcatcatatg
    53401 tccgatgacc ttttatatta tcttctcttg aaccgatttc aattaatcta tctaatacac
    53461 ttacattttt accatagaaa tctggtttga ataacattaa ttctttaatg ttaacatcac
    53521 cgaatttaac accgtagtaa cggtttaagt atgttaaacc taataatagg gcagctttat
    53581 ttttctcaac tttatcaaga atcatttgtt gagctgcaga tgaattattc agttgatgat
    53641 cttcattttc aactaattta gttactaata tgtttaaatt agcttttaca tggtcaaaac
    53701 tttcttctaa ataaaggtct ttaattgcat ttactctatt agaccctgtt ctgccaagtt
    53761 tttggtaaat tggattagat tgaagctcaa tagggcttaa gatatttacg ataccgttaa
    53821 ttaaagcact atgatctttt tgaacgatat taggtgtata tttaatacct aagtcagtta
    53881 tagtgtattc tctaacatta cttagacctt catcactaga agataggttg aagtagtctt
    53941 ttgttccatc agcataatga acgataattt tgtttgcatc acctaaatca gttacaaagt
    54001 tattattgtt cataggagta accgatagaa tctctttagt atttaacttg ttgttcttat
    54061 ctagtttatt agcttgatta acgataaaat ctttgttata gaatggttgt agtttttcaa
    54121 tattcttata agcaagttta tagtctgcat tataatcttg aatagactcg taagctgctt
    54181 cacgactgct aacattattc aatttgttca attcataagg ttcacttacg aatttagcag
    54241 cagtaatatt gaaactagca acttttgcat cagcctcaga tttagataag tgttttaatt
    54301 tatttttgtt tttattatct ttaccagttc catcttcaga agagctatat ccaataactc
    54361 caaataaatt agacacaaaa ggatttgcat ctccatcatt aacatcgttt gaaccgaata
    54421 tttcctgacc tttaataact ttcgcatatg ttacattatc ttgaaccgct ccatatggcc
    54481 aagttttaga ggttattcca ccaacatatt tagtattttt aacatcaaga ataccttttg
    54541 ctacagagtt tgtaagtttt ccttttgtcc ctgatagcca gctatgagct ttatattgaa
    54601 cgaaaggaac aagcatactt gcatttgcgt tatttgctgt aatagtagca tcaacgtagg
    54661 ctctattaac aaaccccata tagttagaac cggcaatacc tccaactgtt gaattattac
    54721 cagcagaatt tatactaccg ataaatgcca cattttctaa agtagcgtct tcttttatgt
    54781 tatttacgaa cccagcaaca ttatttctag ctgttatggt tccgattgct ttgatatttt
    54841 ctatacgtgt cgttccactg atttcatttg ctattgcagc gatattatct tgattagata
    54901 aatcaatatc aatattttca aaatttatat ttttaacagt tccagcctta atcttatcga
    54961 ataaaggatg ttccaaatta tggatagcat agcgtttatc accatcactc aatagtttac
    55021 cagtaaactc tgaagtaata taagatttcc ctttaggaac aacgttacga gcgctcatgc
    55081 tttgacccag tttaaattca ccggcaggat ttgtctgaat ggcttggatc aattcttcaa
    55141 agtcgtagaa aataccagcc tgactagctt tgggtttttc aatatagtag gtataagttt
    55201 cttcaaagcg attatcgaca ttacgttgga ccaagttatc cgctactgct attaccttgt
    55261 agacttgttt tccatcaatt gttgactctt caattttttg aaccgctagt agattggtct
    55321 tatggtcatt agaggtaact tttaaataat aatttgacaa atcagttggc actgaagtca
    55381 atcgagtttc atcagtttca acttggtttt catatttgat taaatccgtt cttataatat
    55441 cttttatttc aacttttttg agatcaattc ttagcggttc ttctttcaga acttcttcct
    55501 catccccctc accacggtca taaaccatct ttgtttcaag tttataatcc ttgtagtact
    55561 gcaaatctgt cagggtagtt gtcaagtctt ctggtgaaac attcaaggtt ttgacaatct
    55621 catcaccttt tttcagagtt agggtaatag atttaatggc tgccttactt ggattttcta
    55681 aactatactt aacatctgaa gtacgcttca aatccttaga ttcaatttct gtgatggtca
    55741 acactggttt ttcaaagctc ttggtaccac gtttcaaaat tttgtcttga ggttcctcaa
    55801 ggatttcctc tgtaactttt ggagcgtctt ctgttttaac tcccttaatg gtattaaagg
    55861 tcttggtgat ttttttctgg ccttcttttc cttcttgagc tacaacttct aagccttttt
    55921 tcagttggtc atcttcttta acaacttcct taaatggaat cttttcaaga ctttcttcta
    55981 taagagttcc ttcaattggt tttgtaccac ggattacctg ttgatttaca ggctccttgg
    56041 tcacttccgt actggttgaa aggactttgt ctgtttccac accttccact gtttcgtaag
    56101 ttgttttcgt aacttgaact cctttagaac caggattttc aactacttcg tcacccacat
    56161 attttgtgtc atccggaact acgtctgttg tgaaatctaa ttcactttca atagacttct
    56221 caactgtacc tgttgttact ttatattctg gatgtacttc ttgtactggt gcttgacctt
    56281 ctttgccttt ttcttgcgta cctttagctg ttttagtctc ctcttttggt tctacagttt
    56341 cttcaggaac ttctggttgc ttttctggct caactggtgc cgttggtgcc ttttcgtctt
    56401 ctcttggcgc gactggttct actgatggtt caacttttga ttcctcagct ggtttgtctg
    56461 atggttgact ttccgatttg actggtgctt gttcatctgt ttttgaatca actgctccac
    56521 ctacttcttc aactggagct gattctactg aatcttcttt cccctcttct actttaggaa
    56581 gggtgtcgtc agtaggtttt acctccgatt ttggttcttc ctttggactt tcttctgttc
    56641 taggtgcttc ttcttttgga gcttcctctg tctctactac ttggttttct gtcctagctt
    56701 gctcctgatt tgttgttgat tgaggagtct caacttcgac tacagtcacc tctccaggtt
    56761 ttgctgaggt ttcttctaaa acagtgtcca agccaagcgt tttgaggatg tcacctgata
    56821 gataaccaac atagcgatag ccatccattt caacaacacc ctctcgacta gccagcgcta
    56881 gggtcgcaac tgggtctaca gcccctgcac taggaagaac taccaatccc atagctccaa
    56941 ctagaaagac gctagcaatt ttctttctct tgtagattaa aagcaagctc ccaacagtca
    57001 gcaaaccaaa agctgtcaaa acagatgctt ctgtccctgt ttgaggcaac tgatcttttt
    57061 gatacaccaa accatataca acttcattcc tgtcaggctt tcctgtctga attaaatctt
    57121 tagcttcttg tgaaataatc tctttattta catagtgata ggtggctgcg tccactacag
    57181 aaggagccat caaaaggctt ccaagaaata cagagcctac aactccctta atcttacgaa
    57241 ttgaaaaacg gtctttttta aacactttta tctcctttat tcattctcaa gacttcctaa
    57301 tagcatcttg cggatagtgc gcacgcgcac ctccgattaa ttttggacga ctagccagtg
    57361 ccgttacatg ggcatgacca atctctctca aaatagggcg aatcggaacc tgaacatgct
    57421 tgacatgcat gccaattgca gtgtctccga tatccaatcc agcatgagcc ttgataaatt
    57481 caacctcaac tggatcctgc ataaacttaa aggctgccaa ctgccccgaa cctcctgcat
    57541 gaagagtagg atggacactg acaatttcca gatcaaactg ctctgccacc tgacgttcaa
    57601 caacgagagc ccgattgaca tgctcacaac cttgaactgc taaatggata cctctactac
    57661 ctagaatacc caagatagtc tccactatca gctcaccaat ctcttgactg gattctttcc
    57721 caatctgacc acctagcacc tcactagaag atagacctaa aacaaaaagg gccccctgct
    57781 tcaaattggt cttttctaaa acatcttcca ctacctgacg tgtttctctt tgaatctgtg
    57841 tctcgttcat ctctgttacc tctgttgtca ctcttctatc ataccgtttt ttcttgtttt
    57901 tagcaagata gacaacctag aaagtttgcc caattacgca taaaactccc agaattgact
    57961 gggagttagc tagtttctat tctatttata tatatttcaa ctttcgtccc tttttggggt
    58021 ctagaatcaa tcttcatctg gtaattggct tcaaaatgaa gtttgagccg ttgatcgaca
    58081 ttttgaagac caactccccc acgtttgagt tgactttgac tactatcacc agcatcttgg
    58141 aagccaacgc catcatcctc aatacggatg accaatcccg aatcctgttt ctggacagaa
    58201 agtttaatat ggccctgacc ttccttttcc ttaatgccat ggtaaagagc attttctaca
    58261 aggggttgta ggaccagctt gggtaagact aaattatcaa aggcaacatt ttcattaatt
    58321 tcatattcca gcttatctcc atagcgttgt ttctggataa agagatactg gcggacatga
    58381 ttgatttcgt cagagagaca aatcaagtcc ttgccttgat tgagcgccaa gcggaaatag
    58441 gttgccaagg acttggtcac ctgcaccact cgctgactat catgaaattc agccatccag
    58501 atgatggtgt ccaaagtgtt atagaggaaa tgtggattaa tctggctcga aagggcttga
    58561 agttggtact gacgggtcgt ttcttcctgg ctacgaatag ctaccatcaa ctgatcaatc
    58621 tgatccaaca tggcattaaa ttggcgagtt acttctctca gttcataggc accaacttcc
    58681 ttggcacgaa gattttgagc accagaagca atttccaaca tggtttctct caaatccttc
    58741 aaaggagcaa tccagcgttt aagactgaac cacactaagc agagacaaac aagaagagat
    58801 gtgacactgg ccccaagcaa ggtccacaag agctgactcc gaacctggtc taacttttcc
    58861 aatgatgaca cgccaagtac cgtccaatca gttcctgcaa tcttctcttg actgacgtag
    58921 gatttgtgac caggagtata accctgacct gtctcgatgt agggtttcat agcctccatt
    58981 ttgctagacg aactataaac tgtgtgttga ggatggtaga caaattcatg gttttcattg
    59041 ataatgaagg caaagccctg ctgccccaac tggagttgat tgagataggc ttccagagtt
    59101 tcataagaaa tatccaaacg aagcacacca agattggctc cctttgcatc aacaagttct
    59161 tgagtgacag aaatgaccca ctgactatct gatttacgag ctggagtcaa aacaggcata
    59221 gctccctgat gaatggcctt ttggtaccaa tcctcagcca tcatatcaga ggaagttttc
    59281 atctgcacac tgtcatctgt agaaatgacc tgaccagatt tggtcaccag cacaacagtt
    59341 ttcaagtcct tatctgactt caagatggtc aaaaacaaat ctcggattcc ctcgaccttg
    59401 tcttgactgg gattctcagc ataggccaga acatccgtct gctgggtcaa accagtcgag
    59461 gtggtttcta gttttttgat ataagactga ataaagtggc tagtctggct gatggtcgtt
    59521 tggctgttgc cctcaatggt ggcctcaatg gctgaagaac ttgattgata gtagaaagtt
    59581 ccaaccagag ctaggagaat gagaaagacc agaaagatgg aaataaccat tctaactaaa
    59641 agagaagaac gcttcatcgg tcttctccct tcttaaactg acgaggtgtt acacctgcaa
    59701 tctgcttaaa acgttgggta aaatagttca tatcttcaaa accaaccttc tctgcgatct
    59761 cataaatctt caaatctgta gttaaaagca agagcttggc ttgtttaaca cgttctctca
    59821 ccagataatc ctgaaaaggc aagcccaact ctttcttaat caaggaactc agataggtcg
    59881 gactaaaacc taagtcactg gctaaagact ttaaactaaa ttggctatca gccagatgag
    59941 actggatttt ctgggccatg tttccttcaa acctattagt caataaatct tgtaactgct
    60001 cttctttctc ttccttgtct agtttttgtt tgattttccc caacatttcc tcaatatcct
    60061 gacgagaaaa gggtttgagt aggtagtcgt ccacacctag tttgacagca gacaaggcat
    60121 aatcaaaatc atcgtaacct gttaaaaaga ccaaatgaac ctgaggatag gtttctcgta
    60181 ccagactggc caactggatg ccatttagat gaggcatgtt gatatcggtt aaaatgatat
    60241 ctggcacctg cttttggatc aattcccaag cctgccttcc attttcagcc tgaccgatga
    60301 tttccatatc gtaggctgct acattgacca gtttagtcaa accttgtctt accagatatt
    60361 catcttctac gattaagatt gtgtaggtca tgatctgctc ctttaccact tactagtatc
    60421 agtatagcaa aattctcctc taactgctta ggaaagacct cttatactca ataaaaatca
    60481 aaaagtaaac taggaagata gccacaggtt tctcaaagta ccgctttgag gttgtagata
    60541 aaactgacgg agtcagtaac cctacatacg gtaaggcgac gctgacgtgg tttgaagaga
    60601 ttttcgaaga gtattaatca acataatcta gtaaataagc gtagcctttt tcttccattt
    60661 ggtctttggg aataaagcgg atagagaggc tattgataca gtaacgtaag ccgcccttgt
    60721 cctgtggacc atccgtaaag acatgcccaa ggtgagaatc tcctactcgg ctccgcactt
    60781 ccatacgcgt catattgtag gacttatctt ccttgtaggt gacaacatct ggactgatgg
    60841 gttgggtaaa actaggccag ccacaaccag actcaaattt gtcttttgat gaaaagagag
    60901 gttccccagt tgctatatcc acatagatac cggattcaaa tttatcccag taacggtttg
    60961 agaaagctcg ttctgtttga ttttcctggg taactgcata ctcctcaggt gacagggtct
    61021 ttttcaattc ctcatcactt ggttttggat atttgctggc atcaatgaca ggataggccg
    61081 cctgattaac attgatatgg cagtagccat ttggattttt cttgagatag tcttgatggt
    61141 aatcctcagc caccacaaaa ttcttcaagt tttccttttc aactgctaga ggttgatcgt
    61201 atttcttagc cacctcatca aagacttggt taatcacttc caaatccttg tcatctgtgt
    61261 aataaacacc agtacggtac tgggtcccca catcatttcc ttgtttattt ttgctggttg
    61321 gattgataat gcggaaatag tgaagcagga tttccttgag agaaatttgc ttggcatcat
    61381 aggtgacatg gacggtttct gcatgacctg tttggttaat caattcgtac ttggttgttt
    61441 ctcctctacc atttgcatag cctgaaacgg catccgtcac cccgggaacg cgtgagaaat
    61501 attcctccac tccccagaaa caacctccag ctagataaat ttcgtgcaag tctgcgtctt
    61561 tactaatttc tgtttttttc actgcttttc ctccttggct aactgccgcc ttttcaattt
    61621 gcgaggcatc tgtctgccct gcatttcgta tcaatagaac atagaaaccg gttatggcta
    61681 gaaaaaatac tcctagcaac aagaagattt ttaacttatc attcataaga cacctcctag
    61741 gctaattcct tcaaagtttg caaaattgca tctttttcca tgaatcctgg atgtgttttg
    61801 accaacttgc cttctttgtc tataaaggct tgggttgggt aagaacggac accataagtt
    61861 tccaaaagtt tgcctgatgg gtcaactagg actgggagat ttttataatc caatccctta
    61921 taccaattct taaagtccgc ttcagattgc tctcccttat gtcctggtga cactactgtc
    61981 aagaccacat agtcatcacc agcttcttta gcaatctcat ccgtatctgg aagactagcc
    62041 agacagatgg aacaccaaga agcccagaat ttgagataga ctttcttgcc cttgtaatca
    62101 gataaacggt aggtcttgcc atctactccc atcaattcaa aatcagccac ctctttccct
    62161 ttagctgcgc ttgttttact agctgtctgc tccgtcttca tttcatcttt cgtttggtgt
    62221 tcactagtca cggacttgcc tgaacaagcc gtcaaacaaa ggagcgaacc tgctccaaga
    62281 acacatgttt gccatttttt catattgata ttcctttcca ttttattcaa ataattgact
    62341 taaaattgaa gcatttccaa acagaaccaa gagtcccatc acaataatga gaaaaccacc
    62401 cacttttttg aggattccga gatagggatg aagttttcgg aaatgtttca aaacataact
    62461 agaggtcaga gctagaagca agaatggtag cgccaagccc agcgtataca ccaacatgag
    62521 accagctccc tgccaagctc ctgaaccacc tgaagccgcc aaggccaaaa cagaccccag
    62581 aaccggcccc acgcaaggcg tccaagcaaa actaaaggtc aagcccaata aaaatgcctg
    62641 actatagccc ttaccatttt gcccctgtcc ttgcagttgt agcctctttt ccttataaag
    62701 ccccttaaag tgtagaatct ccatttggtg caaaccaaga aggataataa ttgccccagt
    62761 aagatattgg aaccaagaag cataaagcaa atcgcctaaa aaaccagctc catagcccaa
    62821 caaaataaat ataaaggaaa ttcctgctat aaaggccaga gttcgtaata aactagtaac
    62881 tgagattgaa aatttgccgc tagaagcctg agcaccatcc ttatcatcta gtaacactcc
    62941 tgtatagacc ggtaacaaag gtaagataca aggagaaaag aaggatagaa tccctgccaa
    63001 aaagacactt agaaaaaaga aaatatgacc cataaagttc ctcctatcat tttattgata
    63061 gatttattat actccttcca ttttcgaaaa aacagggaca atgatagggg aaaataggaa
    63121 tttaatcaga tgatttagaa atcttggaca aaaactatac aaaaaactgt caaagcacaa
    63181 aagcgcatag tatcaaggtt ctataaagtt ttgatactat gcgcttttgt aatggataaa
    63241 tagttagtct tttttaaaga ccggatcttt caaactctgc atactggcat tgataaccgc
    63301 gcctaggata acaattttag caatcaagat aaaccaaaac atcataacaa caagaagaac
    63361 ggaacctaaa attcggacat ccaccaaatg atggacatag taattgagat aactagagaa
    63421 cagagttagt aaacctaaaa tcactaagag aacaaaggca ctgcctggta gggtatagct
    63481 aattttcctg ttagatagat tgggaagaaa ataataaagc atgaccaaga tagcaaagag
    63541 gagggcgtaa atcagaggac ctgccaaccc ttgtaaagcc tgatagataa tgccatcttt
    63601 tgtccaataa tgagcaagta aagccaaaat catctgacca aataagatca aaaacaaggc
    63661 aaacgcaaag aggagctgca agccaaaact gactaggaga cttagcatct gatgggaaat
    63721 aagtccacga ctcttttcga cgccataagc cttgttaaaa gctttttgca agaaattcat
    63781 agattttgaa aaactccata acgccgataa aacagaaaaa ctcaataaac ctgttgaagg
    63841 ttgcgtcaaa acttctctgg ctattttttc cacaccttca tagaggcttg ggggcagaac
    63901 gtctttcata aagcacagaa attctcccac aggaatctga aaatagggga ggatattgac
    63961 caccaccaaa agcaggggga aaatcgaaat caaccaatag taggctactg cgacactggt
    64021 caactcacta tctgatgctt gataataatg caaaaaagct tttaataaag gcttgtctat
    64081 cagctctttc caccactttt tcatgtcata ctccttcatt tataatctta tactcaatga
    64141 aaatcaaaga gcaaactagg aagctagccg caggttgctc aaagccctgc tttgaggttg
    64201 tagatgaaac tgacgaagtc agtcacatat ataatccaag gcgacgctga cgtggtttga
    64261 agagattttc gaagagtatt aactaatttc ttcttaccaa ttccaccata tcatacggca
    64321 gggtattggc agcttccttc aaggaatagt tctctaagtt atttacattt tgtcgtaatt
    64381 tcttggcata cttagtcgta atcaatcgtt tttcttcgta ttcgaaaatc aacttgcgct
    64441 ccagataata gcctctcagc atttcatcga tattgttggg tttgacacga ttgataaccc
    64501 gttcgacaaa ggcaccactg ctgataatag ctgtttctcg aagacgagac tcctgcataa
    64561 aactaatcaa agagcgtctg tagactccct tcaggttttc caaactttca ataatcatct
    64621 ctgtattggc aagatagagc tctgcaattt ggtcataatc aagagcacgg agacggcttt
    64681 gctccttgtc cttccagcta cggaaggtct ttccaagagt aaaaacttca tgaaggagaa
    64741 aacgtaaaat cctcaaggaa acaagaaaat aataggtcag tcttgaggca agtttacgat
    64801 tgattccttg ttctatattt ttcagataac gttggtaaac tcggtaagca cgattgctaa
    64861 tgttcccctc ttcataggcc tgttccaaac catcactttc aatactaaga atcaagagtt
    64921 tcaaagcagc ccaatcttct tgatcatcct ggttttcttg gcttaaaatg agattttcaa
    64981 tacgtccatg ataattgtca atagccgcat agaggggaag tttatttctg gtgtcttcca
    65041 actctttttc caactctagc gttacttcat tcaaaatggc gatatgcatg agataatcct
    65101 tgctttcttc ctcttcatca gaaagatgag gcaagaccaa gagacctgtt aaaaagctga
    65161 caagcgtcac acctgcaaca aggaaaagca aaagaggata ctcctgttct agattacttg
    65221 gtatcaagag aatcgtagca atcgacaccg ttcccttaac acctgaaaag gtcaagagaa
    65281 acatgtcctt catatactta tttagctttt tcttgaggcg tcgggttcta taggcataat
    65341 agccatagat cataataaaa cgaatgacaa agaggacaaa ggtaagggcg atgagagata
    65401 gcaataaaag tagaggatta tagattggat tggtcaagat aggttctgct atcatttcca
    65461 actccatccc taaaatcaca aagacagaac cgttgagcat aaaggtcact gtatgccaga
    65521 ccgtctcggt caccgtatcc acttgggctt cgaggagcgt gattttcttg aagcgacttg
    65581 cctttaaaat tccagcaact acgacggcaa taatacctga aacatgaact tcttctgcca
    65641 gaaagaaggt cactagaggc aaactcaatt ctaataaaag ttcactggca atatccgttg
    65701 cgcgcacact tagcaagaag gtatggagga agcggttggt catggccgtt aaaaatccaa
    65761 ttaaaaaacc gcctaggatt gaaaagatga gcgaactgct agcttgcccc agagaaaaag
    65821 ctccagttgt ccaagctgtc aaagctacct gaaaagccac caaaccagaa gcatcattca
    65881 agagtccttc gcccttaaga atattggaca cgcgcttagg aaagctaaaa cgctccgaaa
    65941 gagaggcaaa ggccaccaag tccgtaggac caagggctgc cccaacagcc aagcaagctg
    66001 ccaagggaag gctgaaccaa agaagatggg ccaagccacc caaactcaag gtcgagataa
    66061 aaatcactgg aaatatgaga taaacaatga ttcgccagtg ttttaaaata gccgtaacat
    66121 ctgcttcttc agcctctcgg aaaagcaagg gtccgataac cagtgccaaa aacaactccg
    66181 tattaaggtg aaagtcagta ttgggtaaaa agagaccaat cacaattccc aaaagaatct
    66241 gcaccaaagg gagaggcaaa aagggcagga gcttattggt tgtacttgag acaatcaaaa
    66301 ccagtaaaaa taggatgagg taaatcagta attccacgca cgtcctcctt aatctttttt
    66361 acaacaggat tcaaatatct ccttctgctc tttgattttt tggtcaatct tggaacagtc
    66421 tttgtgctca atttttctct ggcaccgttc catttcaaga gcaactaatt ttttcttgat
    66481 tttaagcatt tttttgctca tatgcgcttg gtctagcacg cccaccgatc gttcgtggtg
    66541 ggttgattca acaaaattct ggcgcatggc atccagcttt tcgtgtaggt attgtttatc
    66601 catgtctgta tctctctaat ttttcaatca tcactaaaaa cggcgggttg ttgacttggt
    66661 ttaaagttcg gtaaatggca gctgtgtact cttgttggtt caactggatc acaaaatcca
    66721 agacagcatc tctctcgaga tcgcctcctt catgaccata gtaaatcata atagcaattc
    66781 gtccaccttt gacaagtaag ccacatagct tttctaatgc ctcaatcgtt gtctgcggtc
    66841 gggtgatgac agacttatca gctgacggca aatagcccag attaaaaatc cctgccttag
    66901 cttttatcac aaactggtcc agtgtctcat ggccttgcaa gattaactgg gcatttgtca
    66961 agtcagcctg atgcaaacgc tcttgggtct tttccaaggc ttgcttctga atatcaaagg
    67021 catagacttg cttggctagc ttggctaaaa aaagcgtgtc atgaccattt cccatagtcg
    67081 catccactac gacatcctct tttgtcacga cctcagccaa aaaatcatgt gccatctcaa
    67141 gtggtctttt cattttcaaa ctcctgtttt acagccttgc atccttgaac acttccacga
    67201 cgtcgcatct ccatctcaat gctgttgaga gcttcccatt tattgaggct ccacataggc
    67261 ccaagcagca tatccctagg cgcatctcct gtaattcgat ggatgacgat atgtttggga
    67321 ataatttcca gttggtcaca gatgaccctg acatattcgt cctgactcat caattgtaaa
    67381 cgcccctcat ggtaatctcg ttgcatacga gtatttgtca taagatggag caaatgcagt
    67441 ttaatccctt gaatatcgtt atccgtgaca caacggcgga cattttcaac catcatctca
    67501 tgggtttcac caggcaaacc attgatcaaa tgggaaacaa tctcaatttt tggatacttt
    67561 ctcaaacgct tgaccgtttc cacctacaat tcataagaat gcgcacggtt aatcaggtca
    67621 gaggttgctt cataagtagt ttgcaagccc aattcaaccg tcacatgcat gcactccgat
    67681 aactcagcca aatattcgat ggtttcgtct ggtaaacagt ctgggcgcgt tccaatattg
    67741 attcctacca cacctggctc attgatagcc tgttcataac gctctcgaat aacttccacc
    67801 ttttcatggg tgttggtaaa attttgaaaa taaaccagat acttctgaac atctggccac
    67861 ttacgatgaa taaagtcaat ttccttataa aattgctcac ggataggcgc atctggtgcc
    67921 acaatggcat ctccagaacc ggaaaccgta caaaaagtac agcctccatg agccacagtt
    67981 ccatcacgat tgggacagtc aaatcccgca tcaataggga ctttaaaagt cttttctcca
    68041 aagagttttc gataataatc attcaaggta ttataagatt ttataacttt cattataaca
    68101 aaaatcaccc acaatctcaa aagcctgact ttcctataaa ttcctctgtt tctcgtttcc
    68161 attagccttt ttttatgata caatatgggt atgattttaa tgaaattagc atctatttta
    68221 ttattgatac tgaccttagt cgtctgcatt atcctaacca aactttttag attaaaaaaa
    68281 ctaggacgaa actttgcgga tttggctttt ccagtcttgg tatttgagta ttacttgatt
    68341 acagctaaaa cctttaccca taatttcctc cctagactgg ggctagccct ctcgttccta
    68401 gccattattc tcgtcttttt cttccttttg aaaaaacgca gcttttacta tcctaaattc
    68461 atcaaattct tctggcgtgc aggattctta ttaaccctta tcatgtatat agaaatgatt
    68521 gttgaattgt tcttaatgaa atagtcgaat ccctaagcat tttctaggga tttttgcttt
    68581 ctctacaaaa tagtatagac aataacacta tacaatttta tacaaagaaa agagtctggg
    68641 acaatagtct cttatatcca aaaaggcaac ggatttgccg ttgctttttt gcatggttac
    68701 gatagtcttg gtaaaataga attgcttaat aaaccattta gaaaggctat cccatgcata
    68761 ttcactataa cacaaatcaa acaactttac cactagaaat cagttccttc ttaccacaag
    68821 accatctcgt ctttactatt gaaaaagtgg tgaatacctt ggaggaacgt cacttctacg
    68881 ccttctatca tgcctttggt cgcccgtctt atcaccctaa aatgcttgta tctactcttc
    68941 tatttgccta ttcacaaggg attttctctg gtcgaaaaat tgaaaaatgg aagagttagt
    69001 gaccttagat tgtttgttta ttgacggaac taagattgaa gccaatgcca acaagtatag
    69061 ttttgtgtgg aagaaaacga cagagaaatt ctccgccaag cttcaagaac agatacaagt
    69121 ctattttcaa gaagaaatca ctccccttct gattaaatat gccatgtttg ataagaaaca
    69181 aaagagaggg tataaacagt cagctaaaaa cttagcgaat tggcactata atgacaagga
    69241 ggatagctac atacatcctg atggctggtg ctatcgtttt caccatatca agtaccagaa
    69301 aacacagaca gactttcaac aggaaatcaa ggtttactac gctgatgaac ctgaatcagc
    69361 ccctcaaaag ggactgtata tgaacgaacg ctatcaaaac ttgaaagcta aagaatgtca
    69421 ggcgctttta tctccccaag atagacagat tttcgctcaa cgcaagattg atgtggaacc
    69481 tgtctttggg cagataaagg cttgtttggg ttacaagaga tgtaatctga gagggaagcg
    69541 tcaagtgaga attgacatgg gattggtact tatggccaat aacctcctaa aacatagtga
    69601 aatgaaataa gaacaggaca aatcgataag gacagtcaaa tcgatttcta acaatgtttt
    69661 agaagtagaa gtgtactact ctagtttcaa tctactatac aataagagaa cgactcaaaa
    69721 ttaaaaagct agagttccgc aattggaaat atctagcttt tttgtggttg agaactattt
    69781 tgttccagac tctttatctt ctatttagga caagagtttt tctttggtct ttaatgataa
    69841 agaaggtatc aaaatttcta gtcttctttt ttacctttag taactactaa tcctgcactc
    69901 aaacctagaa gagctaaacc tgctgctact gctgcttggc ttgccgcact acctgtattt
    69961 ggtaactggg ctttattagt ttgactagct tcacttgaat caattggttt tgtatctgct
    70021 ttttctgaca cttgtggttt tttagcttct tgagctactg gtttggttcc aaccaagacg
    70081 atgcggtctg tcggagcttc taccacttca cggagttttt cttccttact tccatcagga
    70141 ttaatcgctg taaagatacg ttctttacca gtttttcctt cttgttctac acgagtttca
    70201 cctagataca gtgttgaatc ttttttctca actgtcttgt aggccaaatc tttttcaaca
    70261 aattcgagtt ttggaagatc ttcttgtaca gcagcaactg tcttctcaga aactggtttt
    70321 tccttagtca agtggatacg gtattccttg acttgttttc cactttctga aacgaggcga
    70381 acaagtactg gaaggctatc ttctccacta tctaccacag ttgaagctac ttgattgttt
    70441 tcttcaactg agacttttgg ccgttgacct ttataggtaa tttgatagtc ttgacgattt
    70501 tcagcgaaat cagcaagttc ttttccatct acaagaatct tcgattgcgt gctttcttga
    70561 ggcaattcac ttggtgcaag gaaggtcatc tcaatcatcg caacaccgct cttatctgct
    70621 ttacgctcca tacgccatct catagctttg gctttgacag ctttaaatgt tacgttgatt
    70681 tcatcaccag ctgcgatgtc tttatccgca cgataaggca cagcttccca attttctgga
    70741 ttgttgaatg gatggtctgc gtcgtaggct tggtagtttg aatagtaggt tggcacttca
    70801 aactctggac cgacatagcg ttctaaaacg agtttagttg gtgcatccgt accactatct
    70861 gcaaagaagt gaagtttggc ttgagcaaca gtccgttcta caatcttacc attttcacgg
    70921 aagatcacac ccgctgatac ttctggatta gaagatggtg ttggtgacca gtttgtccaa
    70981 cgacgatttt ctgaatgatc tccgtcattg agatagtcaa cgcggtcatg agagtttttg
    71041 tcaatatcat ttgttgctga agcaaaggcc tggttactgt tttcatcata gttagggtta
    71101 tctgaaagag cctcaccaag tttgtctgtc actcgtacag tgacctcagc aacaaggtca
    71161 ctaccaagga cacggcctcg aatagtaaat tgacctgctt ttgtcagatt ttccgctgga
    71221 acttcttccc attcaactgt caggtctttt gtttcgtagc tgtctttacc tgtgaagtaa
    71281 actggaacct tagtcggcaa ttcaagtgct tgacctactt gtagcaagcg agcttgttta
    71341 accgcagcaa ctggtttatg agaaagtaag ttcttatcct tagtgaagtg cagacggtat
    71401 tctcctaaga tatcgccatt ttcagctttc gcgatgacac gaactggctc accttcacga
    71461 acgcttggaa cgacggtagc gagaccattg ttgctaacac ttgctgtgac tgccggaact
    71521 tttccatcta cagactcaag gtagtagtct gtcaaatcag ggttgaagtt tgctaagtct
    71581 ttgccgtcaa cttggattct tgtttgtcct tgcttggctg ccgcaacttg tttcgcaaag
    71641 atttgtacct ctgtgataga cgttccacgc ttgttatctg ctttaaccat gcgaatacga
    71701 acagcatagg tttcaacttt atcaaagcta aagtggttca tttctccagc cttgagttta
    71761 gcaggggctt ttagattagt aactggtttc cagttggcag aatcattaaa gacatggtcc
    71821 tcattaccaa caaaactagg gtttttagga gctgttggga cagtcttgcc aacataatac
    71881 tcaatcacat aagacttcgg tgcaccaact ccatggtctt cgtggaatcc gacacttaga
    71941 ttatcaacgg agcgtttgct caagatacct gaatctccaa acagaacacc gactgaagct
    72001 tctggattac tacgattcca gtttgtccaa cgattggctg gttggttatt gtaggaaatg
    72061 agcttgtcat taacatttga aactgggtcg cttggatttg aatctgaagc aaaggcaagt
    72121 ggcaattctg aaccggtcca ttggtcagaa atgtttgcac cttgctcagt ttgagcagat
    72181 acgcgaacat gaagtttagt tgttaattga gtaccttcta agcgaccatt aactgtaaag
    72241 acaccttcct tagcgtattg ctctggacga atcgcatccc atgcaacctt agctgatgaa
    72301 acgtgaccat ttgaatcata tgtccgaacg ctttctggta attgtggtgc ttctgcgatt
    72361 ggagttgtca cactgacttc ttcaactgaa acgatacctt ctacagagac ttttgcacgc
    72421 gcttcaaggt caattccttc aactttacct agtacttcaa atatttgata ggagtctagt
    72481 ttttctttcg gaatagcttg ccaagtgact ttatgagttt tagggaaacc tttgtcatac
    72541 tcaactgtta ctgttgctgg aagacttggt tcctgatgca aatctgtgac tacatttaca
    72601 ggacggatag attgcgcaat cttcttctca gtattggctt ggatagtgag ttcaacttgg
    72661 cctttagctc cctcatattc agcgttcaga gtgactgctc ctggcttatg caactcaagc
    72721 attcctttac gaattgcgac ttccccttca ccacttgtag agaaggttac tttatcagct
    72781 ggtaatacag cttgcgttcc atcttgatag tgagctcgaa ccgacaattt gacagtttgg
    72841 tcttctttga gactgtcagc tttttccact tgcaagctca agtgagcaat ttttggcgct
    72901 tcttcaagga attgaattgc ataggtttga agagggccac catctttagg ctgaataaag
    72961 atgctcgcac gcatgccgtt tgctgcgctt gcttgaagaa ctgtcacatc agcattttca
    73021 gcacttgctg tgacttctgg caattgggca ccataagata gagtacgata ttgcattggt
    73081 tgtcgactag taagacctgt tactgcttca cctccaacag taacagttgg cactacaggt
    73141 gctgcaggat tgccttcttc taccacaagg gttgcatgaa ttggttgacc ttctaaataa
    73201 ccggtcgctt gaatacgaga acctggaatt gctaacttag ctttatcttc ttcggcaatc
    73261 tcccacttgt ccacttcata ctcttgtaca cttccatcag tcaaaacata ggaaacagat
    73321 ttgtctacag aattcaagtt agtatttgga gcaatacgtt tcacaactgg tagctctgat
    73381 ttaagagcaa tcacttctac acgagcttct acttctcgtc cgtcagccat acctttcacc
    73441 gttacaatac caggcttgct cacatctact aaagaccagg ttacaggacg ttctgcacga
    73501 ctaccatcac tgtatacaaa cggaacagtg gtaggcattt caggtgcctc tccaataatg
    73561 gtctgtactt ttggcacctc tgtccccaaa acagtctttt cttgtccttc tttcttacca
    73621 gtaaagacag tgacttggtt cgatttcaag agatcagagt gggcagtaag ggtgaatttc
    73681 cctgcttgtt cagttgattt gacaatggca acacctttac cattaaatgc tttacgaatc
    73741 caagaaccat ctgcttgcgc cttatagcgt tcacggctgg cttgttctcc gttatctaca
    73801 ccgaccagtt gaccttggcc atgcaattgg aagcgaacca gattattagc agttggaacc
    73861 acattcccct ggctgtcaac aatttcatag tagatgtaag tcaagtcttt tccatctgct
    73921 gcaatcgcat ggtcttcctt aataagacga actgccgctg gcttaccagc agtcgtaatc
    73981 ttatctcgag caatttcctt gccagattca tcacgagcaa ttgcttccaa ggtacctggt
    74041 tgataggcaa ctttccattc aagataaagt tcattagcat ttgcaccttc ttggtaagtc
    74101 cgcccatcgc tggtttgttt tttattgaaa gtcttaagac caagagattt tccattcaag
    74161 aacaattcta cactagaagc attcgaataa gcacgaactg gaatcttacc ttctgagtca
    74221 gctactttgg atgctaattc tttgttttcc cagttccagt gaggaagaag gtgtaccatc
    74281 ggtttcttct taacagaaac ccattggctt tggtagagat agaagtcatg ttttggaatg
    74341 ccggctgtat ctacgatacc aaagtaagag ctcttaacag gagtttgatt ttggttgtgc
    74401 catggtgtag gttcaccaat atagtccgta cctgtccaga taaactgtcc agcatagcca
    74461 gcgttgtcac ggtcaaaagt ccatgaagcg gttgctgttt tcccccaacc cacacgatca
    74521 tttccataat ctgactgttc ataattacgc tcaggtccat tgctatgttt caattcacgt
    74581 tcagggcgat agtaacttcc acgtgtacgg gttgctgatg atgtttctga accgtaaatc
    74641 aaccattttg gatgcttagc tctaagggct ttgtaattat cttcagaata gttaaatcca
    74701 acagcatcga gttcatcagc aattttctca tgccctccgc taccattacc gaaacggaat
    74761 ttatctgctc ccatggtaac atagcgagtc ttatcaacat ccttgataac cttgaccaaa
    74821 cgtttaacag ttgctaaaga gtgggcatca ccattagctt cacctatttc attaccaatt
    74881 gaccacatga agatagcagg gttgtttttg cctctttcga ccatggtacg taggtcaaaa
    74941 tcagaccatt tttcaccttt tcgagcttct gggtgagtgg catctttttc aaagaaacgt
    75001 ccatagtcat aaggtttctt gccaccatac caagtatcaa aagcctcttc ctgaacgagt
    75061 aaacctagtt ctgctgcgat ttgcaaggtt tgctcactag cagggttgtg ggttgtacgg
    75121 atggagttaa ctcccatctc cttcatttgt ttgagacggc gatattctgc tttatagttt
    75181 tcttctgctc caagcgcccc atggtcgtgg tgcaaggata ctccatggaa tttaatacgt
    75241 tcaccattca aagagaaacc ttcatttgga gtccagtgat agtaacggta accaaacaaa
    75301 tccttcttag catcaaccaa ttgaccgtca cggtaaacac gcgtaatcaa ttcgtacaag
    75361 gcaggtttgt catttaaaac ggtccagagt tttggtcttt caacttctaa aatcgcatct
    75421 aggcttgttg attcatgtgc ttttaaggta cgactcgctg tacgaactaa gcctgttaca
    75481 gcatgaccac ctcgttcaac gatttgatat tcggctacaa gttcatggtc tttgtcgtcc
    75541 gtattgacga ttttgctggt cacatgagtt tcaaccttgc catgttgttg ttcttcaagt
    75601 tttggtgtta aaatagttgt cccatttttc tcaacatgca ccttatctgt cacttgtaaa
    75661 gtcacatcac gatagatacc acttcctgaa taccaacggc tacttggctg tttgttgact
    75721 gcatggacag caatcacatt ctcacgacca tctttgtgaa ggtatttggt gatatcgtat
    75781 gagaactggt tataaccatt tggataatgc cccactaact gaccattgac ataaacttga
    75841 gaatccatgt agacgccatc aaaagtaagg cgaacatttt tcttgaggtc tttttcatct
    75901 agtttgaaag tcttgcgata ccaagcttcc ccaccgttga gctgtccacc ttcattttgt
    75961 gcaggagatt catgatcgaa atcgttaaag atactccagt catacggtaa atctaatttt
    76021 ttccacgtag atacgtctgc atcaggttta atggcttcct tagaatttgc attgagttta
    76081 aagtaccaat tttgattaaa atccactttc ctgtcttcaa tcatttgatt cacttcttca
    76141 tttgttacag ctttagcatc ttccttgagc ggtttttctt gacttgaagc ttgtgattct
    76201 atccttggag ctttttcttc cggtttagca gacacttttt cctcttttgg agttacggct
    76261 tcatcttctt tcttctcaga tgcaatagcc tcagttgaac taggttcact ttgttctgtc
    76321 ctttcaacta catttttagt ttccaaagct ttatcagcct tttcttctac tatcattttt
    76381 tcctctttag gtttctcagc agtatgagta ataagtgttt catccgcata aactacagat
    76441 tctccagcta tatttcctcc taatagaact gcacaagtcc caatcattac tgagcaagct
    76501 cccacagcaa acttacgaat gctataaact cttttccgat tccaatggcc tttccccata
    76561 aaaccctcct tatattatat ttagtgcagt tagctactac caaagcccaa gtggtataca
    76621 tggtatgaca acctagtttc aacaatttac actctgcgaa aatccaattc aaacttcgtc
    76681 agtgtcgcct tgccgtagat atgattactg acttcgtcag tttcatctac aacctcaaaa
    76741 ccatgttttg agctgacttc gtcagtttca tctacaacct caaaaccatg ttttgagctg
    76801 acttcgtcag tcttatctac aacctcaaaa ctgtgttttg agcaacctgc ggctagcttc
    76861 ctagtttgct ctttgatttt cattgagttt atattttata ggagcgcatt attttgcttt
    76921 tgctgcgtac tcttcgttac gtttgatcat ttgttttctg taccaagcaa agataccgat
    76981 atagaataca aggaagacta ctgcaccaag gattgctttg atatcaccag ttgtagtgtt
    77041 accaattgtc caaccaagaa gtttttcgat tggtccttca agagtagagt gagtaatcaa
    77101 ttgagtttgg ctcacacctt ctgggaaggc acctacacct ttagcaagtt ctgttgcaaa
    77161 tggtgcaata agtgtacctg aaagaaggaa gagtggcaac aagagtgttc cgaagataat
    77221 catacggagc aatttaccac gagttacaac caagagagct ggagtaacac ccatagcgat
    77281 gatacctgca agtggcaaga taccatttcc aacttttgaa agaagcactg cttcaatcaa
    77341 catgattggt gcaagtacgt tggcacaagc ccagatttca gcacgaccag cgatgaatgg
    77401 ccagtcaaga ccgatattga atttacgtcc ttgaagacgt ttagtagcaa cgtttgtaat
    77461 accttgtgat agtggttcta cggctgcgat gaaccatgaa ccgataagtg agaagagttc
    77521 caaagataca ccggcagtca aaccaagaga caaccatcct ttgataacaa gacgccattt
    77581 atctgcatct gcaacacctg caattggatg tggagttccc ataataccga taacgatacc
    77641 aaggatgaaa ccgatgaaaa atttagatcc ccagaaaccg attttcttgt tcaatttagc
    77701 agcatcaaag tcatatttat caaggcctgg gaagaatttt tcaaaaatct tatccaaaac
    77761 catgataact gggttcatca tgtagttcat gtgagttgat gtcattggtg atgaacttgg
    77821 ggcgttaaga aggtcatcaa atgtaggttt catcaagtca gagttgataa ttttcaacac
    77881 accgacaagg acgatagctg ctgtagcaat aaagagtgaa accccttgac tcacaccatt
    77941 gttatcagca taccatttaa tcaagagacc tgtgatagac aagtgccaga tatcaaagat
    78001 atcgacatca agtgtatcgg ttttcttcat agcaagcatc actacgttga caatcaacat
    78061 gatgagcaag aagtatagtg tccaagcaga accccaagtg attgttgcga gtggtgccca
    78121 accaacgtcg gtaatactca attggatacc agtgttttca acgaattttg caagtgatgc
    78181 tgagaaagca ccatttagca taccgatgat agcaccgata cctgtaagag cgatggcaag
    78241 tttgatacca ccttcaagcg ctttggagaa tttcactcca aaaagtaaag ccaatactgt
    78301 caaaatgatt aacatgatga caggtccacc catttctaaa atgggattga aaacctttcc
    78361 gattaggtca aagattgcat ccataacagt tcctcccttt tttatgttat atgaatgtta
    78421 acaaattaga attagcttaa tccgtgttct ttaatagctg cttcaatatt gtcaaatact
    78481 ggagcgctca ttgctgggat acggaataag attggcccag cttcgataac tgggatacct
    78541 ggttcaaaac caag
//
LOCUS       DBERXF010000004        77745 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.04, whole genome shotgun sequence.
ACCESSION   DBERXF010000004 DBERXF010000000
VERSION     DBERXF010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 77745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77745
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.04"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            342..1208
                     /locus_tag="ACL8JK_000269"
     CDS             342..1208
                     /locus_tag="ACL8JK_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1785221.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYRVNQLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAHFLYKLEENMSMA
                     LKVEHYIADITE"
     gene            1358..1492
                     /locus_tag="ACL8JK_000270"
     CDS             1358..1492
                     /locus_tag="ACL8JK_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785222.1"
                     /translation="MRSLFKKIVAVLVIGLILLGIARTPQVHKIARGIDPGPANGQAL
                     "
     gene            1931..3361
                     /locus_tag="ACL8JK_000271"
     CDS             1931..3361
                     /locus_tag="ACL8JK_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGS1785223.1"
                     /translation="MQILISEVNVTSFGITREILKKMDFNFSKMGSEEAKFLIFPELP
                     RGGELSLTARQSYDSQLRYSMLPRVEDIMKKIVNQLREHLKILDIELSDLSYLSEGDQ
                     FILKELSSHVKINIKITPIKKIRYVYEDIFLNQSAEELHELGLKYLSAGDLWASKKIF
                     TYLVNKYDNRRDVFKLATTYNMLLETEKAEYYYNLYKHDGKVDHIVAANYMLAMLYAR
                     HHPKYLQDDQKAIVLLNEAYDLIKDKVTLESIFNRNGYALLLFKMGKVEETIILLKRC
                     LNQIKQLDNSSSSVVLHESVLWFNLYQCYVTIGDNTNSRKTFYILKNMDPLFIEYYLE
                     YSRNLLETDVENFLEFIESMPHHSNNFAEKYSLLGYYFRGTAKSLEYFSKAFELSNRT
                     FSFWYDITYELTEFNLYNEAYNNLPLLNNKLYELNDEDLLNYILISAEIFYNLDRLDE
                     FKRTIEIGYRIFPDSESIKEIIENAE"
     gene            3358..4533
                     /locus_tag="ACL8JK_000272"
     CDS             3358..4533
                     /locus_tag="ACL8JK_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS1785224.1"
                     /translation="MKRYKTLFIKYPDSFQFLVFNILFYLSMSLSRSVHSIWFDLNGS
                     LLNYSISYSAMAFSGMFAGILGRRINYFNLRNLIRIGVILYSIGLLLRLFPNDWLISL
                     ISGLISGIGAATIILLLRTWAVGIGKEKDRVVTISLKRFSSSLGTSIGGILSGILLYC
                     LIYFFHSMAYPIVLASASMLCLVTFFCIPKIDSFVDKSERAERILESSNYMKKRIIFF
                     GIFSGLIASIFSPYLPVILRRQEISEVFIGPVLTILSLLTIYFSSIFSSRKVDNHKQG
                     YYILSELLISILTLLFSFHLKYYLVITILIIRVFFVNLSSITQELMELSIYPKEKISY
                     FYGISQTSYFIGDTLGGFIGGWLFNQDMKYSIYLFSVLLLFNAVLFNRFYLRNNKNS"
     gene            complement(4667..5724)
                     /locus_tag="ACL8JK_000273"
                     /pseudo
     CDS             complement(4667..5724)
                     /locus_tag="ACL8JK_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681261.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            6295..8244
                     /gene="mutL"
                     /locus_tag="ACL8JK_000274"
     CDS             6295..8244
                     /gene="mutL"
                     /locus_tag="ACL8JK_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGS1785225.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGYGISHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGYGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(8569..9036)
                     /gene="ribE"
                     /locus_tag="ACL8JK_000275"
     CDS             complement(8569..9036)
                     /gene="ribE"
                     /locus_tag="ACL8JK_000275"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HGS1785226.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(9037..10242)
                     /locus_tag="ACL8JK_000276"
     CDS             complement(9037..10242)
                     /locus_tag="ACL8JK_000276"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HGS1785227.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(10262..10897)
                     /gene="ribE"
                     /locus_tag="ACL8JK_000277"
     CDS             complement(10262..10897)
                     /gene="ribE"
                     /locus_tag="ACL8JK_000277"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HGS1785228.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(10882..11982)
                     /gene="ribD"
                     /locus_tag="ACL8JK_000278"
     CDS             complement(10882..11982)
                     /gene="ribD"
                     /locus_tag="ACL8JK_000278"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HGS1785229.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(12117..12231)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            12388..12981
                     /gene="ruvA"
                     /locus_tag="ACL8JK_000279"
     CDS             12388..12981
                     /gene="ruvA"
                     /locus_tag="ACL8JK_000279"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGS1785230.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            12991..13554
                     /locus_tag="ACL8JK_000280"
     CDS             12991..13554
                     /locus_tag="ACL8JK_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGS1785231.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTETELEAMLENPAIIRNRAKLFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWRGLK"
     gene            13551..14228
                     /locus_tag="ACL8JK_000281"
     CDS             13551..14228
                     /locus_tag="ACL8JK_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS1785232.1"
                     /translation="MMSNKNKGILIFAILYTVLFMFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(14383..15414)
                     /locus_tag="ACL8JK_000282"
     CDS             complement(14383..15414)
                     /locus_tag="ACL8JK_000282"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HGS1785233.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGRAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(15669..16352)
                     /locus_tag="ACL8JK_000283"
     CDS             complement(15669..16352)
                     /locus_tag="ACL8JK_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGS1785234.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(16364..17308)
                     /locus_tag="ACL8JK_000284"
     CDS             complement(16364..17308)
                     /locus_tag="ACL8JK_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGS1785235.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            17440..20271
                     /gene="uvrA"
                     /locus_tag="ACL8JK_000285"
     CDS             17440..20271
                     /gene="uvrA"
                     /locus_tag="ACL8JK_000285"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGS1785236.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDINQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            20264..21325
                     /locus_tag="ACL8JK_000286"
     CDS             20264..21325
                     /locus_tag="ACL8JK_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGS1785237.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKVGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            21457..21855
                     /gene="spx"
                     /locus_tag="ACL8JK_000287"
     CDS             21457..21855
                     /gene="spx"
                     /locus_tag="ACL8JK_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HGS1785238.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            21921..22490
                     /locus_tag="ACL8JK_000288"
     CDS             21921..22490
                     /locus_tag="ACL8JK_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP0191 family lipoprotein"
                     /protein_id="HGS1785239.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            22577..22843
                     /locus_tag="ACL8JK_000289"
     CDS             22577..22843
                     /locus_tag="ACL8JK_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGS1785240.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            22847..23266
                     /gene="ruvX"
                     /locus_tag="ACL8JK_000290"
     CDS             22847..23266
                     /gene="ruvX"
                     /locus_tag="ACL8JK_000290"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGS1785241.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGKFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            23282..23587
                     /locus_tag="ACL8JK_000291"
     CDS             23282..23587
                     /locus_tag="ACL8JK_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGS1785242.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            23945..25195
                     /locus_tag="ACL8JK_000292"
     CDS             23945..25195
                     /locus_tag="ACL8JK_000292"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGS1785243.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLICQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLDIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            25279..25710
                     /locus_tag="ACL8JK_000293"
     CDS             25279..25710
                     /locus_tag="ACL8JK_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0198 family lipoprotein"
                     /protein_id="HGS1785244.1"
                     /translation="MKLKRFTLSLASLASFSLLVACSQRAQQVQQPAQQNTNTANAGG
                     NQNQAAPVQNQPVAQPTDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVT
                     FDSANQRMIIGDDVKIYTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            25856..27388
                     /gene="cls"
                     /locus_tag="ACL8JK_000294"
     CDS             25856..27388
                     /gene="cls"
                     /locus_tag="ACL8JK_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGS1785245.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            27466..27609
                     /locus_tag="ACL8JK_000295"
     CDS             27466..27609
                     /locus_tag="ACL8JK_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785246.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            27646..29184
                     /locus_tag="ACL8JK_000296"
     CDS             27646..29184
                     /locus_tag="ACL8JK_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HGS1785247.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            29304..31511
                     /gene="nrdD"
                     /locus_tag="ACL8JK_000297"
     CDS             29304..31511
                     /gene="nrdD"
                     /locus_tag="ACL8JK_000297"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGS1785248.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLVDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            31523..31663
                     /locus_tag="ACL8JK_000298"
     CDS             31523..31663
                     /locus_tag="ACL8JK_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785249.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKYSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            31707..32213
                     /locus_tag="ACL8JK_000299"
     CDS             31707..32213
                     /locus_tag="ACL8JK_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1785250.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVER
                     YWIEVANE"
     gene            32206..32796
                     /gene="nrdG"
                     /locus_tag="ACL8JK_000300"
     CDS             32206..32796
                     /gene="nrdG"
                     /locus_tag="ACL8JK_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGS1785251.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            32793..33410
                     /locus_tag="ACL8JK_000301"
     CDS             32793..33410
                     /locus_tag="ACL8JK_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGS1785252.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTSAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTAGLPVAHELESLQRDILALQASMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            33676..33984
                     /gene="rpsJ"
                     /locus_tag="ACL8JK_000302"
     CDS             33676..33984
                     /gene="rpsJ"
                     /locus_tag="ACL8JK_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGS1785253.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            34201..34827
                     /gene="rplC"
                     /locus_tag="ACL8JK_000303"
     CDS             34201..34827
                     /gene="rplC"
                     /locus_tag="ACL8JK_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGS1785254.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            34852..35475
                     /gene="rplD"
                     /locus_tag="ACL8JK_000304"
     CDS             34852..35475
                     /gene="rplD"
                     /locus_tag="ACL8JK_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGS1785255.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            35475..35771
                     /locus_tag="ACL8JK_000305"
     CDS             35475..35771
                     /locus_tag="ACL8JK_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGS1785256.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            35789..36622
                     /gene="rplB"
                     /locus_tag="ACL8JK_000306"
     CDS             35789..36622
                     /gene="rplB"
                     /locus_tag="ACL8JK_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGS1785257.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            36726..37007
                     /gene="rpsS"
                     /locus_tag="ACL8JK_000307"
     CDS             36726..37007
                     /gene="rpsS"
                     /locus_tag="ACL8JK_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGS1785258.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            37019..37363
                     /gene="rplV"
                     /locus_tag="ACL8JK_000308"
     CDS             37019..37363
                     /gene="rplV"
                     /locus_tag="ACL8JK_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGS1785259.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            37376..38029
                     /gene="rpsC"
                     /locus_tag="ACL8JK_000309"
     CDS             37376..38029
                     /gene="rpsC"
                     /locus_tag="ACL8JK_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGS1785260.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            38033..38446
                     /gene="rplP"
                     /locus_tag="ACL8JK_000310"
     CDS             38033..38446
                     /gene="rplP"
                     /locus_tag="ACL8JK_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGS1785261.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            38456..38662
                     /gene="rpmC"
                     /locus_tag="ACL8JK_000311"
     CDS             38456..38662
                     /gene="rpmC"
                     /locus_tag="ACL8JK_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGS1785262.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            38687..38947
                     /gene="rpsQ"
                     /locus_tag="ACL8JK_000312"
     CDS             38687..38947
                     /gene="rpsQ"
                     /locus_tag="ACL8JK_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGS1785263.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            38973..39341
                     /gene="rplN"
                     /locus_tag="ACL8JK_000313"
     CDS             38973..39341
                     /gene="rplN"
                     /locus_tag="ACL8JK_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGS1785264.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            39419..39724
                     /gene="rplX"
                     /locus_tag="ACL8JK_000314"
     CDS             39419..39724
                     /gene="rplX"
                     /locus_tag="ACL8JK_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGS1785265.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            39748..40290
                     /gene="rplE"
                     /locus_tag="ACL8JK_000315"
     CDS             39748..40290
                     /gene="rplE"
                     /locus_tag="ACL8JK_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGS1785266.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            40308..40577
                     /gene="rpsN"
                     /locus_tag="ACL8JK_000316"
     CDS             40308..40577
                     /gene="rpsN"
                     /locus_tag="ACL8JK_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGS1785267.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            40862..41260
                     /gene="rpsH"
                     /locus_tag="ACL8JK_000317"
     CDS             40862..41260
                     /gene="rpsH"
                     /locus_tag="ACL8JK_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGS1785268.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            41452..41988
                     /gene="rplF"
                     /locus_tag="ACL8JK_000318"
     CDS             41452..41988
                     /gene="rplF"
                     /locus_tag="ACL8JK_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGS1785269.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            42072..42428
                     /gene="rplR"
                     /locus_tag="ACL8JK_000319"
     CDS             42072..42428
                     /gene="rplR"
                     /locus_tag="ACL8JK_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGS1785270.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            42446..42940
                     /gene="rpsE"
                     /locus_tag="ACL8JK_000320"
     CDS             42446..42940
                     /gene="rpsE"
                     /locus_tag="ACL8JK_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGS1785271.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            42954..43136
                     /gene="rpmD"
                     /locus_tag="ACL8JK_000321"
     CDS             42954..43136
                     /gene="rpmD"
                     /locus_tag="ACL8JK_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGS1785272.1"
                     /translation="MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMITAVSHLVTVEEVN"
     gene            43281..43721
                     /gene="rplO"
                     /locus_tag="ACL8JK_000322"
     CDS             43281..43721
                     /gene="rplO"
                     /locus_tag="ACL8JK_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGS1785273.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            43734..45044
                     /gene="secY"
                     /locus_tag="ACL8JK_000323"
     CDS             43734..45044
                     /gene="secY"
                     /locus_tag="ACL8JK_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGS1785274.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            45195..45833
                     /locus_tag="ACL8JK_000324"
     CDS             45195..45833
                     /locus_tag="ACL8JK_000324"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGS1785275.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQNINDVFSDIEKVLTNLK"
     gene            45950..46168
                     /gene="infA"
                     /locus_tag="ACL8JK_000325"
     CDS             45950..46168
                     /gene="infA"
                     /locus_tag="ACL8JK_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGS1785276.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            46193..46309
                     /gene="rpmJ"
                     /locus_tag="ACL8JK_000326"
     CDS             46193..46309
                     /gene="rpmJ"
                     /locus_tag="ACL8JK_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGS1785277.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            46327..46692
                     /gene="rpsM"
                     /locus_tag="ACL8JK_000327"
     CDS             46327..46692
                     /gene="rpsM"
                     /locus_tag="ACL8JK_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGS1785278.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            46710..47093
                     /gene="rpsK"
                     /locus_tag="ACL8JK_000328"
     CDS             46710..47093
                     /gene="rpsK"
                     /locus_tag="ACL8JK_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGS1785279.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            47136..48071
                     /locus_tag="ACL8JK_000329"
     CDS             47136..48071
                     /locus_tag="ACL8JK_000329"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGS1785280.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            48083..48469
                     /gene="rplQ"
                     /locus_tag="ACL8JK_000330"
     CDS             48083..48469
                     /gene="rplQ"
                     /locus_tag="ACL8JK_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGS1785281.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            48734..49000
                     /locus_tag="ACL8JK_000331"
     CDS             48734..49000
                     /locus_tag="ACL8JK_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGS1785282.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            49010..50347
                     /locus_tag="ACL8JK_000332"
     CDS             49010..50347
                     /locus_tag="ACL8JK_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HGS1785283.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMEGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            50591..51283
                     /locus_tag="ACL8JK_000333"
     CDS             50591..51283
                     /locus_tag="ACL8JK_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS1785284.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(51386..53038)
                     /locus_tag="ACL8JK_000334"
                     /pseudo
     CDS             complement(51386..53038)
                     /locus_tag="ACL8JK_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(53028..54118)
                     /locus_tag="ACL8JK_000335"
                     /pseudo
     CDS             complement(53028..54118)
                     /locus_tag="ACL8JK_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(54131..55252)
                     /locus_tag="ACL8JK_000336"
                     /pseudo
     CDS             complement(54131..55252)
                     /locus_tag="ACL8JK_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085230.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(55839..56615)
                     /locus_tag="ACL8JK_000337"
     CDS             complement(55839..56615)
                     /locus_tag="ACL8JK_000337"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HGS1785285.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            56737..57483
                     /locus_tag="ACL8JK_000338"
     CDS             56737..57483
                     /locus_tag="ACL8JK_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS1785286.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            57496..58476
                     /locus_tag="ACL8JK_000339"
     CDS             57496..58476
                     /locus_tag="ACL8JK_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HGS1785287.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            58671..58991
                     /locus_tag="ACL8JK_000340"
     CDS             58671..58991
                     /locus_tag="ACL8JK_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS1785288.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            59037..59345
                     /locus_tag="ACL8JK_000341"
     CDS             59037..59345
                     /locus_tag="ACL8JK_000341"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1785289.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            59362..60660
                     /locus_tag="ACL8JK_000342"
     CDS             59362..60660
                     /locus_tag="ACL8JK_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS1785290.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            60811..63249
                     /locus_tag="ACL8JK_000343"
     CDS             60811..63249
                     /locus_tag="ACL8JK_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HGS1785291.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            63268..63936
                     /locus_tag="ACL8JK_000344"
     CDS             63268..63936
                     /locus_tag="ACL8JK_000344"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGS1785292.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            63954..65042
                     /locus_tag="ACL8JK_000345"
     CDS             63954..65042
                     /locus_tag="ACL8JK_000345"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HGS1785293.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            65497..67998
                     /gene="leuS"
                     /locus_tag="ACL8JK_000346"
     CDS             65497..67998
                     /gene="leuS"
                     /locus_tag="ACL8JK_000346"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGS1785294.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLDVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            68137..68979
                     /locus_tag="ACL8JK_000347"
     CDS             68137..68979
                     /locus_tag="ACL8JK_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785295.1"
                     /translation="MNRLVNDSRKCEILLFKISIIVVSVIVLVMSIVGAYYFKNCLWD
                     KESLNLTLTLDTLFAVFITFFSFSNDKSSNIFGISPNEIIRTQSEVYQFLFTKSFATL
                     LIVTNLLSIIHYFGAKNLIVSFNETYPRIQSSVGIMWLPLFGILIIYFIWLLIEGLKY
                     IRKINYIIQNREIIYFYSQVKVVDKLTDSESKKYGEYIDLYESCRQNNLSVLLNFLQN
                     SDDKRGVIASNSVRIMFESLDKADQIAALNICRNYVARENVLNKEDAEKLLNEIDKKL
                     EISR"
     gene            69035..69730
                     /locus_tag="ACL8JK_000348"
     CDS             69035..69730
                     /locus_tag="ACL8JK_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGS1785296.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDAL
                     NLPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            69742..70158
                     /locus_tag="ACL8JK_000349"
     CDS             69742..70158
                     /locus_tag="ACL8JK_000349"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1785297.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEHALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPIYQRQGIGSALMKEALKDYKDAYQVQ
                     LVTEETEKNVGFYRSMGFEILSTYNCIGMTWANREK"
     gene            complement(70973..71065)
                     /locus_tag="ACL8JK_000350"
     CDS             complement(70973..71065)
                     /locus_tag="ACL8JK_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGS1785298.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            71199..72197
                     /gene="ruvB"
                     /locus_tag="ACL8JK_000351"
     CDS             71199..72197
                     /gene="ruvB"
                     /locus_tag="ACL8JK_000351"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGS1785299.1"
                     /translation="MSRILDNEIMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEA
                     AKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELE
                     PGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPR
                     IANRLLKRVRDFAQIMGNGVIDDVITDKALTMLDVDHEGLDYVDQKILRTMIEMYGGG
                     PVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            72178..72750
                     /locus_tag="ACL8JK_000352"
     CDS             72178..72750
                     /locus_tag="ACL8JK_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HGS1785300.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            72981..73739
                     /locus_tag="ACL8JK_000353"
     CDS             72981..73739
                     /locus_tag="ACL8JK_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGS1785301.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKYLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEVALQEAILAYNRRHRRFGGV"
     gene            73748..74551
                     /locus_tag="ACL8JK_000354"
     CDS             73748..74551
                     /locus_tag="ACL8JK_000354"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGS1785302.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            74573..75832
                     /gene="rseP"
                     /locus_tag="ACL8JK_000355"
     CDS             74573..75832
                     /gene="rseP"
                     /locus_tag="ACL8JK_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGS1785303.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            75845..77698
                     /locus_tag="ACL8JK_000356"
     CDS             75845..77698
                     /locus_tag="ACL8JK_000356"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGS1785304.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
BASE COUNT        23915 a        13750 c        16681 g        23399 t
ORIGIN      
        1 tctatgtgga gggattgggc tcctatgtgg tggagctttt ctgttctttc tgaaatatgg
       61 tataatagca ctaatcaatt tctaggaaaa tagatacaga aaggggctga aagaactagg
      121 ggaacagttg taattagaag gtgataggta tgaaaagtgg cgttgaagct ggataagttt
      181 ataaagagtt tgaatgaaga aatgaaaagt aaataagttg atgatgaatt gcaaaaatag
      241 attttatata caatttgtat ctttcgaatc attgatttga attttagatt taatcatgtt
      301 acaattaaaa ctgaaatcaa atagaagagg aaaatgcaaa cgtgggcaca ctattagcaa
      361 caagattaaa aaatagacgg aaagaattaa aaatgtctca gcgagaacta gctgaaggta
      421 tctgtaaaca ggggcaaatc agtcgattag agagcggaga gtttacccct ggagcggatt
      481 tcctgcatgc ccttgctaag aagttaaaag tcagtatgga ttattttttt gatgagcagg
      541 ttgtagagaa agttgaggag ttatcggaat ttaagaaatt agcacagaca tttattacaa
      601 atcgcaatta tgagtctttg aaatatatat atgaattgga gaatgtaaaa gctcaccgcc
      661 tatctttagc agataaaatc tacatggaat ggataaaatc tctgatagat ttttattttt
      721 acggacagaa agaagatgcg attgtacgat tagagggggt attatcacag ttaagtgtat
      781 ctgatttgaa ctatctccaa gtttcaaaca ccctattcaa tttttactat gatattggag
      841 atttaggtcg tttcaataaa attcgtgaaa aactagagta tcgagtaaat caactcaatt
      901 tgagtacaat cgaagagtta gagctatcta ttaagtttaa ctacaacgtt tgtcgttatc
      961 tatggttaca gaaaaatatt gaagaagcta ttactaaaat tacagctact ataaaacaat
     1021 gtaaggcata cagaacgaat tatcttttgg ctgatttgta cttattgatg ggaaacgtaa
     1081 gtgaaaattt ctcttctaaa agttcagtga aagaatattt tgagacagct catttccttt
     1141 acaaattaga ggaaaacatg tcaatggctt tgaaagttga gcattacatt gcagatataa
     1201 cagaataatg aatacggtgt tcaagtgagc atcgtttttc aaacccagtt tagatacaaa
     1261 aaagtatcaa acaaaaaaaa ataaaaaaac attataaaaa tacttgacaa gctaattttg
     1321 aagtgataaa ataaatgcaa gaaaaaagga gaggtatatg agaagtttat ttaagaaaat
     1381 agttgctgta ttagttattg gattaattct gttagggatt gcgagaacac cccaagttca
     1441 taagatagct agagggattg atccaggtcc agcgaatggg caagctctct aactgttcag
     1501 actaatctat aacgacatta tgaggtttga taagatttct cctcaccgga taaaaatctt
     1561 aaattttata atagagggag aaattaaatt gaagtttaag aagaagagct taaagcctaa
     1621 gaaaattcgt tttgtactag gttacaatgg cggtgataaa taagtacaag tatgtatttg
     1681 tttttattaa gaatctaaga ttaaatctta gattcttaat tttttattag attttataat
     1741 atttattcta aaaataatag acaagtataa tttatattat atgatatact catctgattt
     1801 acttttaagc tacttagttg aaaacgaaaa attgatcaga attcgttaga tttcagtaaa
     1861 tctggataat tattgtatcg agtatgaata ttttgaaaaa aagaagaatt ttatgtattt
     1921 ggagaagaaa atgcaaatat taatttctga agtaaatgta actagttttg gaattacaag
     1981 agaaatttta aagaaaatgg attttaattt ctcaaaaatg ggtagcgaag aagctaaatt
     2041 tttaattttt ccagagttac ctagaggagg tgagctaagt ttaactgctc gtcaaagtta
     2101 tgatagccag ttaaggtatt cgatgttacc tagagttgag gacatcatga agaaaattgt
     2161 aaatcaactt agagaacatt taaaaatttt agacattgag ctaagtgatt taagttattt
     2221 atcagagggt gatcaattca tattaaagga actatcaagt catgtaaaaa taaatattaa
     2281 aattactcca ataaaaaaaa tacgttatgt atatgaagat atctttctca atcaatcagc
     2341 agaggaatta catgaattag gattaaaata tttatcagca ggtgatttat gggcttctaa
     2401 aaaaatattt acttacttag taaataaata tgataataga cgagatgttt tcaaattagc
     2461 tacaacttat aatatgttat tggaaacaga aaaagcagaa tactactaca acctatacaa
     2521 acatgatgga aaagttgacc atattgtggc agcaaactat atgcttgcaa tgctctatgc
     2581 acgccatcat cctaaatacc ttcaagatga tcaaaaagct attgtattat tgaatgaagc
     2641 gtatgattta attaaagata aagtgacatt agagagtatt tttaatcgaa atgggtatgc
     2701 cctactatta tttaaaatgg gcaaagtaga ggaaacaatc atattattaa aacgttgttt
     2761 aaatcaaata aaacaattag ataactctag ttcttcggtt gttcttcatg aaagtgtact
     2821 ttggtttaat ttatatcagt gctatgtcac tataggtgac aatactaatt ctcggaaaac
     2881 tttttatatt ttgaaaaata tggatccgct ttttattgag tactatctag aatattctag
     2941 aaatctttta gagacagatg tcgaaaattt tctagaattt atagagagta tgccacatca
     3001 ttctaataat tttgctgaaa aatattcgct cctaggctac tattttagag gtactgcgaa
     3061 atcattagaa tattttagta aagcttttga attgtcaaat agaacgtttt ctttttggta
     3121 cgatataact tatgaactaa cggagtttaa tctttacaat gaagcataca ataatttacc
     3181 tttattgaat aataaattgt atgagctgaa tgatgaagac ttactaaatt atattttaat
     3241 ttcggcagaa attttttata atttagacag gttggatgaa tttaaacgaa ctatagaaat
     3301 tgggtataga atttttcctg attcagaaag tattaaagaa attatagaga atgccgaatg
     3361 aaaagatata aaactctatt tataaagtat cctgattctt tccagttttt agtttttaat
     3421 attctgtttt atttatcaat gtcactttct aggagtgttc attcaatttg gtttgatttg
     3481 aatggaagtt tactgaatta tagtatttca tattcagcaa tggctttttc aggaatgttt
     3541 gctggaattc taggcagaag aattaattat tttaatttaa gaaatctgat aagaatagga
     3601 gtaatactat attctatcgg tttattattg agattatttc ctaatgattg gttgatatca
     3661 ttaatctctg gtcttatctc aggtattgga gcggcaacaa taattctttt attgcgaaca
     3721 tgggctgtcg gaataggaaa agaaaaagac agagtagtta cgatttcctt aaaaagattt
     3781 tccagcagtt taggaacttc tattggaggg atattgtcag gcattttgct atattgctta
     3841 atatattttt ttcatagtat ggcgtatcct attgttttag cttcggcaag tatgctatgt
     3901 ttagtaactt tcttttgtat tcctaaaatt gacagttttg ttgataagag tgaaagagca
     3961 gaaagaatct tagaatctag taattacatg aaaaagagaa taatcttttt tggtatcttc
     4021 tcaggtttaa ttgctagtat attttctcct tatctacccg ttattttaag acgtcaagaa
     4081 atatcagaag tttttattgg gcctgttcta actattttaa gtctattaac aatttatttc
     4141 tcttccatat tttcaagtag aaaagtagat aatcataaac aaggatatta tattttatcc
     4201 gagttgttga tttcgatact tactttatta tttagttttc atttaaaata ttatttagta
     4261 ataacgatat tgattattag agtatttttt gtaaacctat catcaattac acaagagtta
     4321 atggaattat caatttatcc aaaggaaaaa atttcatatt tctatggcat ttctcaaact
     4381 tcctatttta taggtgatac tctgggagga tttattggag gttggctatt taaccaagat
     4441 atgaaataca gtatttatct gttttctgtg ttattattat tcaacgctgt gttatttaac
     4501 agattttact tacggaataa taaaaattct taagggacct ctaaaaaaaa cagaagatta
     4561 aaatacagta aaaaaatcaa ctaaaatagt cccaaagtaa agaaatactt gaacctattt
     4621 tagctggttt tctttttttt cacctctaat tgaggattat tctattttag ggtatactcc
     4681 cccatgtttt caaccctaat cgttggattt gttcgaaacg acagatatta tacaacaaat
     4741 ttgtcaaaat cacattcgtt tttgtacgcg ctaatccaat tcctctaaaa tgacttcctt
     4801 tcatcgtatt tttaataaca ccaaaaacat gttccacacg acagcggata cgagaaatag
     4861 actgattgat acgcttatcc aaatcagtca aggttttatt tcgaaaagca ctatcatcaa
     4921 agatcggctc cttactctca cacaactctt ccaagacgcg agaatcgtga atattagcag
     4981 aagtaatctc aaatttcttg attagttttg atttttggtc gatactaata ctcaatgaaa
     5041 atcaaagagc aaactaggaa gctagacgca agttgctcaa aacactgttt tgaggttgca
     5101 gatagagctg acgtggtttt aatttgattt tcgaagagta taatatgatt tgtataacca
     5161 aagtaagttg gttctcccta gtccatcctg tatccctatc tttttgagaa ggcttcgctg
     5221 tattccaatc tgtcggaatc tttccttttt tgatttgttg attctcttct cgtgtattgc
     5281 gttgtttagg ggattctaca aatggggcat ctactatctg tccctgatga gctaataagc
     5341 ctttttctgc tagtgttaga taaaattact cagataattc ttgttctttc tctgatttgg
     5401 tcaagcgttc tctatacaac cagatggttt ttgcatcatg tactttacat tcatcacaac
     5461 ctgtggaatg acgaaatgac agacgatgaa agagttgata ttccatcgca tcatctgata
     5521 aattatggag atgttggatc aagagcacct taaatatcat gaaaaaatca tgcggaggga
     5581 gtccgccttt tgatggtttc taaaaatctg ctcaagaata ggtctaattt gctcccaatc
     5641 cattgcctta tctaagcctt ccaatggatt gcccattgaa ctcaattttg atagtgtttg
     5701 ttcatcatct ataaaaaatt ccatcgccta acctagctta cctctatctc tagtatctca
     5761 tgttttacga tttttttggg tttttagagg tgcccttaaa ttcgttcatt aatgttacga
     5821 gactggccga aaattagtct ctaaataaaa ccacacagtg atttcagtct tgaatccaat
     5881 caaactgaaa gaagcactat gtggtttttg aatagtgggc tagattcttg atcaatttgg
     5941 tgagattcat ggtaatcgcc caataacgag gtatattgaa aaatctacag actagagaac
     6001 tcactgatag ttcctaatct ggagatttct tatttgcact tttcttgtac aactttagtc
     6061 catggtaaat aagcctctaa aacatcttta tttacgagag tctcctcgcc tagctttcta
     6121 gtttgttctt taatttttat tgagtatacc actattttac tccctctggc aagggacttt
     6181 gtctatgtgg agggattggg ctcctatgtg gtggagcttt tctgttcttt ctgaaatatg
     6241 gtataatagc actaatcaat ttctaggaaa atagatacag aaaggggctg aaagatgtct
     6301 catattattg aattgccaga gatgctggca aaccaaatcg cggctggaga ggtcattgaa
     6361 cgtcctgcca gtgtggtcaa agagttggta gaaaatgcca ttgacgcggg ctctagtcag
     6421 attatcattg agattgagga agctggtctc aagaaggttc aaatcacaga taacggttat
     6481 ggaatttccc acgatgaggt ggagttggcc ctgcgtcgcc atgcgaccag taagataaaa
     6541 aatcaagcag atctctttcg gattcggacg cttggttttc gtggtgaagc cttgccttct
     6601 attgcgtctg ttagtgtctt gactctgtta acggcggtgg atggtgctag tcatggaacc
     6661 aagttagtcg cgcgtggggg tgaagttgag gaagtcatcc cagcgactag tcctgtggga
     6721 accaaggttt gtgtggagga tctctttttc aacacgcctg cccgtctcaa gtatatgaag
     6781 agccagcaag cggagttgtc tcatatcatt gatattgtca accgtctggg cttggcccat
     6841 cctgagattt ctttcagctt gattagtgat ggtaaggaaa tgacgcggac agctgggact
     6901 ggtcaactgc gccaagctat tgcagggatt tacggtttgg tcagtgccaa gaagatgatt
     6961 gaaattgaaa attctgacct agatttcgaa atttcaggtt ttgtgtcctt gcctgagttg
     7021 actcgggcta accgcaatta tatcagcctt ttcatcaatg gtcgttatat caagaatttc
     7081 ctactcaatc gtgctatttt agatggttac ggaagtaagc tcatggtagg ccgttttcca
     7141 ctggcagtca ttcacatcca tatcgacccc tatctagcgg atgtcaatgt gcatccaacc
     7201 aagcaagagg tgcgaatttc taaggaaaaa gaactgatga cgctggtctc agaagctatt
     7261 gccaacagtc tcaaggagca aaccttgata ccagatgcct tggaaaatct tgccaaatcg
     7321 accgtgcgca atcgtgagaa ggtggagcag accattctcc cactcaaaga aaatacgctc
     7381 tactatgaga aaactgagcc gtcaagacct agtcaaactg aagtagctga ttatcaggta
     7441 gaattgactg atgaagggca ggatttgacc ctgtttgcca aggaaacctt ggaccgattg
     7501 accaagccag caaaactgca ttttgcagag agaaagcctg ctaactacga ccagctagac
     7561 catccagagt tagatcttgc tagcatcgat aaggcttatg acaaactgga gcgagaagaa
     7621 gcatccagct tcccagagtt ggagtttttc ggacaaatgc acgggactta tctctttgcc
     7681 caagggcgag atggacttta catcatagat cagcacgctg ctcaggaacg ggtcaagtac
     7741 gaggagtacc gtgaaagcat tggcaatgtt gaccaaagcc agcagcaact cctagtgccc
     7801 tatatctttg aatttcctgc ggatgatgcc ctgcgtctca aggaaagaat gcctctctta
     7861 gaggaagtgg gcgtctttct agcagagtac ggagaaaatc aatttattct acgtgaacat
     7921 cctatttgga tggcagaaga agagattgaa tcaggcatct atgagatgtg cgacatgctc
     7981 cttttgacca aggaagtttc tatcaagaaa taccgagcag agctggctat catgatgtct
     8041 tgcaagcgat ctatcaaggc caatcatcgt attgatgatc attcagctag acaactcctc
     8101 tatcagcttt ctcaatgtga caatccctat aactgtcctc acggacgtcc tgttttggtg
     8161 cattttacca agtcggatat ggaaaagatg ttccgacgta ttcaggaaaa tcacaccagt
     8221 ctccgtgagt tggggaaata ttaaaagtat aaaaaagtct gggaaaaatt ttcaaaatca
     8281 aaaaaacgca taaaatcagg tgttcaaaaa ccttgatttt atgcgtttta tcatggaaat
     8341 agttacttca ttttttccta attcttttcg aaactctttt taaacgacgt cagttttatc
     8401 agtaatctca aaacagtgtt ttgagctaat tttgccagtt ttgtctgtaa catcgaagtt
     8461 gtgtttgacc actctgcgac tggtttccta gtttgctcta tgattttcac agagtattaa
     8521 attgcgattt tgccaagttt ctttattcgt ctaaaagtag agtctgttct atgcgtctaa
     8581 tgtacgaatt aggttgacca tttcaatagc tccttgtgca cactcagaac ccttatttcc
     8641 tgctttagta ccagctcgtt ctatggcttg ttcaattgta tctgtcgtta gcacaccaaa
     8701 cataacagga atttcgctat ttaaactgat ttgggcgatt cccttagata cctcgctaca
     8761 tacataatca taatgacttg tatttcctct aatgacagct cccaagcaga taattgcatc
     8821 atatttttta ctttttgcca tttttgatgc aatcagtggt atttcaaaag ctcctggaac
     8881 ccaggctacc tcgatatctt tctcgtttac attctctctt ttgagattat ctagtgctcc
     8941 agataataat tttgaagtta taaattcatt aaatctcgct acaacaatac ctattttaat
     9001 attgtttgct actaaattac cttcataagt gttcatttat ttttcctcca tatttaaaat
     9061 gtgacccatt cgatttttct ttgtttctaa ataaaaacta tcgtaaggat tggcttctat
     9121 ttcgattgat attctactgg aaatggtaat tccatatttt tctaactgtt caaccttgtc
     9181 aggattattt gtcagtaaat gaagtgactg aagtcccaga tctttaagca tttgtgctcc
     9241 aatatgatat tctcttaaat caccttcaaa gcctaatgca agattggcat caagcgtatc
     9301 catgccttga tcttgtaaat gataggcttt taatttattg ataagtccaa ttcctcgtcc
     9361 ctcctgtcgc aagtaaagta agacacccga accattctca acaatcattt tcatagcttt
     9421 atcgaattgc tgtccacaat cgcaacgtaa agagcctaaa acatctcctg ttaaacattc
     9481 ggagtggacc cgacataata cattggcttc atcctctatg tttcccataa taagagcaag
     9541 atgatgttcc ccatttagtt tatctatata gctaattgct ttgaaattac cgtatctagt
     9601 aggcatattg acagttgaaa ctcgttctac cagctgatca tatacttttc tatattcttg
     9661 taattctttg atggtaatta gtggaatgtt gtgtttcttc gaaaactgaa ttaaatcatc
     9721 tgttctcatc attttgccat catgattcat tatttcacaa cataggccac actcttttag
     9781 tccagctaat tttaataaat caacagttgc ttctgtgtgt ccatttcttt ctagaacacc
     9841 accttttttt gcaattaaag gaaacatgtg tcctggcctg cgaaaatcag agggtgttat
     9901 atcttcagct acacacatac gtgcggtcag tcctctttcc tcggcagaaa tacctgtggt
     9961 cgtttcttta taatcaattg aaactgtaaa agcagtctta tgattatctg tattgttttc
    10021 aaccataggt gaaagcatta attgattagc taaactttcg ctcataggca tacaaattaa
    10081 tcctttggca taagtagcca taaaattaac attttctgtt gtagctgctt gtgcagaaca
    10141 aattaagtct ccttcatttt ctctatcctt gtcgtctata acaagaacaa gtcgtccctt
    10201 ctgcaatgct tctaatgctt cttgtatttt tcgatattcc attgactgat tatcctttct
    10261 gctaaaatcc attttgatat aatagttcct tagatatttc tgattttgga gagttatcca
    10321 tcagtttttg cacatattta cctaagatat cattttcaag atttactgta ctcccgactt
    10381 gtttactctt aagaatggtt tgttccaagg tatgagggat aacagatact gaaaagttta
    10441 ctttggagac tttagcgaca gtcagactaa tgccgtcaat tgtaatagat cctttttcaa
    10501 ctattaaatc taaaatttct ttttgtgtgt tgatttgata ccatacagca ttatcatctt
    10561 tttttattga cgagattttt cctgtaccat caatgtgtcc tgtaacgacg tgacccccaa
    10621 gtcgaccgtt gacagataag gctctttcta gattcacctc acttccatgt tttaatagag
    10681 taagagctgt tcgactccat gtttcattca ttacatcaac tgtaaaggat tgatggttga
    10741 aatgagtaac tgtaagacag ataccattta ctgctatact atcgcctaaa tggatatccg
    10801 ttaatatttt tgaggcttta attgatagtt tacaattacg agagtctttc tgtattcttt
    10861 caacttttcc gatttcttca attattcctg tgaacatgga taaatcactt cactttctat
    10921 gagatagtca tttcctattt gagaaaaagc ataaggtttc aatctaatag cgtcatttgg
    10981 caaagaaatg ccttcacctc cgacaggaaa cttggcactg cctccaaaaa tttttggtgc
    11041 aatatatatt ttcagctcat caacaatttg ttgttccaaa gcactccaat tcattagact
    11101 gcccccttct agaactaggc tatcaatctg catgtttcct agatgttgca ttaaactcga
    11161 taagtctata tgattgcctt ttttctttat ggaaagtatt tcacagccat gattttgata
    11221 tagcttcatt ttatttttgt cttcagagga agtggcaatg taagttttaa tatcatttgc
    11281 tgtttttacg attttagagg taagaggagt tcgtaaatgt gtatcgcata tgatacggat
    11341 aggatttttc ccttcctcca atctacatgt cagcaaagga tcgtcttgaa taacagtatt
    11401 gactcccacc ataattgcac taacatagtg tcgtaactga tgcacatgct ttcttgcttc
    11461 ttcttcagta atccatttgg attgatttgt tttagtggct atttttccat ccattgacat
    11521 tgcatatttc ataaaaacat agggtacatg ctgggtaata tactttctaa aactttttat
    11581 taagttaaga cactcatttt ctaaaattcc aacagtaact tgaagattat tttcctcaag
    11641 tatctttact ccttttccag atacaatagg attacagtct aggcttccaa tgactactct
    11701 tgtaatacca ctatcgatta tagcatctat acagggaggt gttttcccga agtgacaaca
    11761 gggttcaagt gttacataaa gcgtcgctcc gacaggggat tctctacagt ttttaagagc
    11821 atttctctca gcatgtgggc caccaaaaaa ctcatgataa ccttgtccga tgatgtgatt
    11881 atcttttaca ataactgcgc cgaccatagg attgggattg acgtaaccag cccctttttg
    11941 tgccagtttt attgctaatt tcatatattt tgaatcgctc atctcactac ctccaaaaaa
    12001 aatatacctt gaatagggga ctactcaagg catacaaaag aaaacttatg cgattaacaa
    12061 aaatactctg aaatgacaag taatcatttc agagcacgca aaaagcacaa atatactttt
    12121 atcttctttc atccagacta tactgtcggc tttggaattt caccaaatca tgcctttcgg
    12181 ctcgtgggct ataccaccgg tagggaatta caccctgccc tgaagatagt tattcaatta
    12241 cagatgatta tagtacttaa ttttgaatat gtcaacagat aaataccgat tgtttttgat
    12301 atactgtatt tgtgataatc gattctcgct cctcggataa agaaaatatg atatactaga
    12361 taaacgaaat aagagagaag gaatactatg tacgcatatt taaaaggaat cattaccaaa
    12421 attactgcca aatacattgt tcttgaaacc aatggtattg gttatatcct gcatgtggcc
    12481 aatccttatg cctattcagg tcaggttaat caggaggctc agatttatgt gcatcaggtt
    12541 gtgcgtgagg acgcccattt gctttatgga tttcgctcag aggatgagaa aaagctcttt
    12601 cttagtctga tttcggtctc tgggattggt cctgtatcag ctcttgctat tatcgctgct
    12661 gatgacaatg ctggcttggt tcaagccatt gaaaccaaga acatcaccta cttgaccaag
    12721 ttccctaaaa ttggcaagaa aacagcccag cagatggtgc tggacttgga aggcaaggta
    12781 gtagttgcag gagatggcct tcctgccaag gtcgcagtgc aagcaagtgc tgaaaaccaa
    12841 gaattggaag aagctatgga agccatgttg gctctgggct acaaggcaac agagctcaag
    12901 aaaatcaaga aattctttga aggaacgaca gatacagctg agaactatat caagtcggcc
    12961 cttaaaatgt tggtcaaata ggagcagaga atgacaaaac gttgttcgtg ggtcaagatg
    13021 accaacccgc tctacatcgc ctatcatgat gaggagtggg gtcagcccct ccatgatgac
    13081 caagcattgt ttgagttgtt gtgtatggaa acctatcagg caggcctgtc ttgggaaacg
    13141 gtactcaaca aacgccaagc tttccgagaa gcctttcata gctatcaaat tcactcagtc
    13201 gcagagatga ctgagactga attggaagcc atgctggaga atccagctat cattcgaaat
    13261 agagccaagc tttttgctac acgcgctaac gcccaagcct ttctacagtt acaggcagag
    13321 tacggctctt ttgatgccta tctttggtct tttgttgagg ggaaaactgt cgttaacgat
    13381 gttcctgatt atcgccaagc cccagctaaa acacccttat ctgagaaatt agccaaagat
    13441 ctcaaaaaac gaggcttcaa gttcacaggc ccagtcgccg tattgtcttt tctacaggct
    13501 gcagggctag ttgatgacca cgagaatgat tgtgagtgga gaggtcttaa atgatgtcta
    13561 acaaaaataa gggaattctg atttttgcga ttctctatac agtcctcttt atgtttgatg
    13621 gcgttaaatt gctggcttct ttaatgccat ctgccattgc aaattatctt gtttatgtag
    13681 ttttagctct atatggctcc ttcttgttca aggatagatt gatccaacaa tggaaggaga
    13741 ttagaaagac taaaagaaaa ttcttctttg gcgtcttaac aggatggctc tttctcattc
    13801 tgatgactgt tgtctttgaa tttgtatcag agatgttgaa gcagtttgtg ggactagatg
    13861 gacaaggtct aaatcagtct aatattcaaa gtacctttca agaacaacca ctactgatag
    13921 ctgtttttgc ttgtgtcatt ggacctctgg tagaagaatt atttttccgt caggtcttat
    13981 tgcattactt gcaggaacgg ttgccaggtt tactaagcat tattctggta ggacttgttt
    14041 ttgctttgac tcatatgcac agtttggctc tatcagagtg gattggtgca gttggttact
    14101 taggtggagg ccttgccttt tctattattt atgtgaaaga aaaagagaat atctactatc
    14161 ccctacttgt tcacatgtta agcaacagcc tctccttaat cattttagct atcagtatag
    14221 taaaatgaaa taagaacagg acaaatcgat caggacagtc aaatcgattt ctaacaatgt
    14281 tttagaagca gaggtgtact attctagttt caatttactg taatatgtga tgaaaatgcc
    14341 agtaatgata ccgagaaaaa agctgagaaa cttttcccag ctttatttgt tatagtcaaa
    14401 gcgaatgact tgttcctgtg catctacatg agcatggacc ccaaagggta caattgctct
    14461 tggagttgcg tggccgacat tcagattata gacaatcggg atattgctgt caatgatatc
    14521 caatagtgcc tctttatagt cgtcatggaa agtttcatcc ataggttttc cgaccaagag
    14581 tccattgatg accgcgaata tgccagtgtc ctttaaagtt agcaacatct ttttgaagtc
    14641 ttctggctta ggcttttctt cgcttgtttc gagcaagagg attttccctt cccagtctga
    14701 caagtcaggg aaaagtttgt atttttggca gagctccgtg ctatctgcgt atcgagagtt
    14761 gtcaaagata tcgtagaggg attcgaggca accaccgagg attttcccct cgaattgggc
    14821 ccttccttgc aacaagtcaa aacctgtatt tgtatgactg acacgaggtg ttcccagggc
    14881 cgtgggacta aaatcagttc gttcctcata ccaaacgtca ctagggcgga tttctgaaat
    14941 tcttcccgtc tcaatcaatt ctttaaagta gtgaaggcta taggctagca tttctttgtc
    15001 taattcacaa atgtctgcta aaaaggattg accataaaaa gtcttgattc ctaatttatg
    15061 caacatgagg tggttcatgg ttgtatccga gaagccaaga aaaatttttt gtttgataac
    15121 cttttggagt tggtcatttt caaaaagata aggtagcaag cgataggtat cgtctccacc
    15181 gatggcacat aggatcatgt cgatgctatc atcagaaaag gcatgaatca aatcctctgc
    15241 acgagcttca ggatggtcct tgataaagtc taatcctttt aacgaatggg gcaaaaagat
    15301 gggattgagt cccagatcct tgagacgttg gatacccaag tccacttcgt gtttgacaaa
    15361 atcctctccg ataatgccac tagataaact aacaatacca atagtagaaa ccatatctca
    15421 tcctcctaga aatagattga gcctatttta tcacaaaata taagagaaag ctatgtggga
    15481 tttcagaaga atacttttaa tactcttcga aaatctcttc aaatcacgtc agttttattt
    15541 gcaacctcaa agctgtgctt tgagcaacct gcagctagct tcctagtttg ctctttgatt
    15601 ttcattgagt ataactcaaa aaagtaagtg aaaaagcaac cgcacctgca gttgctttta
    15661 tcgttttctt attcttgata gcgtgttggt cctgcacttg cactacggat attcaagcgt
    15721 ttcttgagat agaagcgaag ggctaggagg gctgctccaa taatagctag tggcaatgga
    15781 tccagtactg ggttaaggct agctggtagg aagcttgttg caaagaagac aagcaaccaa
    15841 aggaacatag aagctaggat aactagtaca gatttccaga aaggtggacg ttgactgcga
    15901 tccatatctg gtccatagta ttggtaaaca aagtagtaca tcaagtagaa ggcaaatcca
    15961 ccaaccagtc caactaatag aagagtaatc aatccatagc cgaaagcttg atctgccgca
    16021 aagaaggttg tgagggcgct gacaagggca aagaggctag tgatgaaaag agctgagtcc
    16081 ataatcatca gttttgggtc atcattttct tttggatgct ctttttcgta ctgctctttg
    16141 acagtgaagc tatgagccca atgagttggt gcgccgtata gggaacgggc agttgtacct
    16201 ttagattgct cctcaaggat ttggggaatg acttcctcaa aaatagtctg gatttcagcg
    16261 tctgttttcc catctttgat gaattgttgg gtagcaatgt ggacaaactc ttggtttttc
    16321 ttagttaatt tttgtagatc aatttgagac ataggaactc ctcttagaac cattttttat
    16381 ggatgagata gagagtgagc gagacactca tagcaaaggc gataaagacg attaaccaga
    16441 aggcatttgg ctctccgttt aggggaattt cattatcctt aaagttcatc ccgtaggcag
    16501 aaaagaccat ggttgggatg gacatgacga tggtcacaag ggccaaggtt ttcatgatgt
    16561 tgttctggtt gttagaaatg atagaggcaa aggtctctgt catagaatgc aagacgtttc
    16621 cataaatatc tgccatctcg atggcctgtt gggtttcaat cagggtgtct tcaagcaggt
    16681 cttcgtcctc aaggtatttc ttgatattgc tggttgaact ggtcaatttc ttaatcacgc
    16741 gctcatttgt tttgagggag gccttgaaat agacgatagt tttttccaat tccatgagct
    16801 caatcaattc ttcattacga gttgattgat gcagttgact ttcgatttgt tcactcttgc
    16861 ggtcgattga acgaagggct gttaggtaaa gctctgcatt gcgataaaga atttgaaaga
    16921 taaaacgtga acgcatgaag gtatagaaat tacgcaatcg acggttgata aagacatcaa
    16981 ggacaggtag tggttccaaa cacgtagtga taatggtttc ctcagtgatg ataataccaa
    17041 gcgggatggt tacgtagtag gtgcggttat ttctttcctc cgtgaccggc acgtctacga
    17101 taatcagggt atactcgtct tcaatggtaa tacgagacat ttcttccgca tcgagcggtg
    17161 ctcgaaggtc ggcaatatca atatcgaagg tgttggcgat ttcgagtgat tcattttgag
    17221 tcggattgac gagattgatc caagtacccg gttcaagcgt atcgatctct ttaaattcag
    17281 ttgttgtaga gagaaaaact tgtttcatat cccttatcct ttctcatttt tcagattttt
    17341 tcacactgta ctattatact acaaaatcgg ccttttgggt aatagaatct cacttttttt
    17401 ggtataatgg taagcaataa tggactagaa agaacaaaga tgcaagataa aattgtcatt
    17461 catggggcgc gtgcccataa tttaaaaaat attgatgtgg agattccgcg agacaagttg
    17521 gttgtcgtga ctggcttgtc aggttcaggg aagtccagtc tggcttttga tactctctat
    17581 gcggagggac aacgtcgcta tgtagagagt ttgtctgcct acgctcgtca gttcttggga
    17641 aatatggaaa aaccagatgt agatgccatt gatggtctca gcccagctat ttccatcgac
    17701 cagaaaacga ctagtaaaaa tcctcgctcg acggtgggaa cgacgactga aatcaatgac
    17761 tatctgcgtc tcctctacgc acgtgtgggg acgccttact gtatcaacgg acatggagct
    17821 atcaatgctt cttctgtgga gcaaatcgtt gataaggttt tggagttacc tgaacgccag
    17881 cgcttgcaga tcttggctcc tgtcatccgc aagaaaaaag gccaacataa gagtgttatc
    17941 gagaaggttc agaaagacgg gtatgttcgt gttcgtgtgg atggggaagt ctatgatgtg
    18001 accgaagtgc cagagttgtc taagagcaag caacacaata tcgatgtcgt ggttgaccgt
    18061 attgttatca aggagggcat tcgtagccgt ctctttgatt ccattgaagc tgcccttcgt
    18121 atcgcagaag gttatgtcat tatcgacacc atggacgact cggagttgct cttctctgag
    18181 cattatgcct gtccagtttg tggatttact gtcccagagt tagaacctcg tctcttctct
    18241 ttcaatgctc cctttggctc ttgtagtgag tgtgacggct tggggattaa gctggaggtg
    18301 gatactgatt tggtagtgcc agatgccagc aaaaccttac atgagggagc gctggcacct
    18361 tggaatccta tctcatccaa ctactatcca aacatgttag agcaggccat gaaagtcttt
    18421 ggagtggcta tggataagcc ttttgaggac ctgtcagaag aagataagaa cttgattctc
    18481 tacggctcag atggtaagga attccatttc cattatgaaa atgaatttgg tggtgtgcgc
    18541 gatatcgaca ttccgtttga gggagttatc aataatatca aacgtcgtta ccatgaaacc
    18601 aatagcgatt acactcgcac tcagatgcgt ctctacatga atgagctgac ctgcggaacc
    18661 tgtcaaggct atcgtctcaa tgaccaggcc ttgtctgtcc gtgtgggcgg ccagcaaggg
    18721 ccacatattg gagaaatctc agacctgtct atcgctgacc acttggactt ggtgagccag
    18781 ttaactttgt ctgaaaatga agccatcatt gctcgtccca ttctcaagga aatcaaggat
    18841 cgtttgacct tccttaataa tgtgggtctt aactatctaa ccctgtcacg ttcagcagga
    18901 accctttcag gtggggaaag tcagcgcatt cgtttggcaa cccagattgg ttccaaccta
    18961 tcaggtgtcc tctatatcct agacgagccg tcaatcggtc ttcaccagag ggacaatgac
    19021 cgcctgattg ccagtctgaa aaagatgcgt gacttgggca atactcttat cgtggtggaa
    19081 cacgacgaag ataccatgcg tgaagctgat tatctgattg acgttggtcc tggtgccggt
    19141 gtttttggtg gtgagattgt tgcagcaggt acacctaagc aagtggctcg caacagcaag
    19201 tctatcacag gtcagtactt gtcaggcaaa cgtgtcatcc cagtaccaga agagcgccgt
    19261 gtcggaaatg gtcgttttat tgaagtgaca ggagcgcgtg agaacaactt gcaaaatgtc
    19321 acggctcgct ttccactagg aaaatttatc gcagtgacag gtgtgtcggg ttcagggaaa
    19381 tcgactctaa tcaacagcat tctcaaaaaa gccattgccc agaagctcaa ccgtaattca
    19441 gacaaacctg gtaagtttaa gactattaca gggattgagc atgtcgaccg tttgattgat
    19501 attaaccaga gccctatcgg acggacgccg aggtctaacc cagctaccta tacaggagtt
    19561 tttgacgata tacgtgacct ttttgctcag acaaatgaag ccaagattcg aggctacaag
    19621 aaggggcgct tcagtttcaa cgtcaaggga ggtcgctgtg aagcttgctc aggtgacggg
    19681 attatcaaga ttgagatgca cttcttgcca gatgtttatg tggcttgtga agtttgccac
    19741 ggaacccgct ataacagtga aaccctagaa gttcactaca aggaaaagaa tatttcgcag
    19801 gtcttggata tgacggtcaa cgatgcggta gaatttttcc aacacattcc gaaaattcaa
    19861 cgcaaactcc agaccatcaa ggatgtaggt ctaggctatg tgaccttggg acagccagct
    19921 accacccttt ctgggggaga agcccaacgt atgaagttag ctagcgaact ccacaaacgc
    19981 tcgacaggaa aatctttcta cattctggat gagccgacga cagggcttca tacagaggac
    20041 attgctcgcc tgctcaaggt tttagctcgc tttgtagacg ccggcaatac agtcctcgtc
    20101 atcgagcaca atctggatgt tatcaagacg gcagaccata tcattgactt gggacctgag
    20161 ggcggtgtcg gtggtggaac catcatcgta acaggaactc cagaagaagt agctgccaac
    20221 gaagccagct atacaggaca ctatttgaaa ggaaagttac atcatgaata aacgcgtaca
    20281 agcatttcta gctaaaatgc aagaaaaaga actagatggt atcatcatca acaatcttaa
    20341 aaacgtctat tatttgactg gtttttgggg ctcaaacgga acagtcttta tcagccgtga
    20401 ccgtcaggtc ttagtgacag actctcgcta tatcatcgca gctaagcaag aaaccagtgg
    20461 ttttgagatt gtggctgatc gtgatgaatt ggctgtcatt gcaggaattg ttaaggacat
    20521 gaacttgact cgtatcggtt ttgaagatga gatttcagtg tcttattacc accgtatgca
    20581 ggcagctttt gcaggtttga acttgcttcc acaaactcag tttgtggaag gtcttcgtat
    20641 gattaaggat gaggcagaga ttgcagcgat tcgcaaggct tgttctatct cagaccaagc
    20701 tttccgcgat gcgcttgact ttatcaaacc aggaaaaact gaaattgaga ttgccaactt
    20761 ccttgatttc cgcatgcgtg agttgggagc atctggctta tcttttgata cgatcctagc
    20821 tagcggtatc aattcttcta aaccccatgc ccatccaatg cacaaaccag tggagttggg
    20881 agaagccatc accatggact tcggctgtct ctatgaccac tatgtcagtg atatgacccg
    20941 gactatctat ctagggcatg ttagcgatga gcaggcagag atttacaata cggttctaaa
    21001 agctaaccaa gccttgattg accaagctaa ggtaggctta ggtttccgtg actttgacaa
    21061 aatccctcgt gatattatca ttgaggcagg ttatggtgac tactttactc acggcattgg
    21121 ccacggtatt ggtctggata tccatgagga accctacttt agtcagactt ctacagaaac
    21181 tattaagaca ggtatggcct tgaccgatga accaggtatc tatatcgaag gcaaatatgg
    21241 cgttcgtatc gaggatgata tcctgattac agagacaggt tgtgaattat tgaccctagc
    21301 tccaaaagag ttgatagtca tttagttgtt tgtcaagaaa aaagtacgaa aatgacgaaa
    21361 aaagtcaaaa aaaattaaaa ataggtcgca agtcggatgt tttttatggt ataatagact
    21421 aaactgatag taacatgtag cgaaaggggt aggtacatga ttaaaattta tacagtctca
    21481 agttgtacta gctgtaaaaa agcaaaaacc tggctcaatg cccaccagtt aagttataaa
    21541 gaacaaaacc ttggtaaaga aggaattacg agagaagaat tactggatat tctaaccaaa
    21601 acagataacg gaatagccag catcgtttcg tctaaaaatc gctatgccaa agcccttgga
    21661 gtggatattg aagatttgag tgtcaatgaa gttctcaatc tgattatgga aacaccgaga
    21721 attttaaaga gcccaatcct tgtagatgaa aaacgcctgc aagttggcta caaggaagac
    21781 gatattcgtg ccttcctacc acgctctgtc cgtaatgtag aaaatgcaga agcacgtttg
    21841 cgtgcagctc tataaacatc aaggctggga gcacttccca gtcttattct attttaattt
    21901 caaaaagaaa gaagaaagaa atgaaaaaaa tagttcttgt tagtctagct ttcctttttg
    21961 tcctggttgg ttgcggacag aaaaaagaaa ctggaccagc tacaaaaaca gaaaaagata
    22021 cgcttcagtc ggcattgcca gttattgaaa atgctgagaa gaatacagtt gtaactaaga
    22081 ctttggtctt gcccaagtca gatgatggta gccagcagac acaaacaatt acttacaaag
    22141 acaagacttt tttgagtcta actatccaac aaaaacgtcc agtctctgat gagttgaaga
    22201 cttatattga ccaacatgga gtggaggaaa ctcaaaaagc tcttcttgaa gcggaggaga
    22261 aggataagtc tatcattgaa gctcgtaaac tggcaggttt caaacttgaa acaaaactat
    22321 tgagcgcaac ggaacttcaa acaacgacta gttttgattt tcaagttctg gatgtcaaga
    22381 aggcttccca gttggaacat ctgaagaata ttggtttgga aaatcttttg aaaaatgaac
    22441 caagcaaata tatttcagat agattggcaa atggcgcgac agaacaatag aaaatccaaa
    22501 taaatagact gcctgaattg tagaaggtaa ggaattatgc tataatggta ctattctaag
    22561 gaaagagggt gttagaatgg gatttactga agaaacagta cgttttaaat tggacgattc
    22621 caataaaaaa gaaattagcg aaactttgac agatgtttat gcttcgttga acgataaggg
    22681 ttacaaccca attaaccaaa tcgtaggtta cgtattgagt ggagaccctg cctacgttcc
    22741 tcgttataat aatgcacgaa atcaaatccg taagtatgag cgtgatgaaa tcgttgagga
    22801 attggttcgc tactacctca aagggcaagg agtcgatcta taacctatga gaattatggg
    22861 attggacgtc ggttcaaaaa cggtaggggt ggcgattagc gatccgcttg gttttacagc
    22921 tcaagggctt gaaatcatcc agataaatga agaacaaggc aaatttggtt ttgaccgcgt
    22981 taaggaattg gttgatactt acaaggtgga acgatttgta gtgggcttgc ctaaaaacat
    23041 gaacaataca agtggaccgc gcgtagaagc tagtcaagcc tacggagcaa agctagaaga
    23101 gttttttggt ttaccagtag actatcagga tgaacgcttg acaacagtgg ctgctgagcg
    23161 catgttgatt gaacaagcag atatcagtcg caataagcgc aagaaagtca ttgataagtt
    23221 agcagctcag ctgattttac aaaattattt agatagaaaa ttttaatata aaggagaggc
    23281 tatgtcacac gatcataacc acgaccacga agaacgtgaa ctaatcacac tagtagatga
    23341 gcaaggaaat gaaaccttgt ttgaaatcct tttgacaatt gatggaaaag aagaatttgg
    23401 taaaaactat gttcttctag taccagttaa cgcagaagaa gacgaagacg gacaagttga
    23461 aatccaagct tactcattca ttgaaaatga agatggaaca gaaggcgaat tgcaaccaat
    23521 cccagaagac tcagaagacg aatggaacat gattgaagaa gtcttcaaca gctttatgga
    23581 ggagtgatac agtctgggag actgtatcag cccaactccc agaaatgggg aagagttgga
    23641 acgtccagtg gatgttttta gcccagttcc tttaaataag agagaactgg taggttcggg
    23701 gggacgtttt tagccctgcg ctagaaatta gaaacgcagg tagtctgaga aactgtatca
    23761 gcccaactcc cagaaatggg gaagggttgg aacgtccagt ggatgtttta ctccacgtta
    23821 atattcatag ttgctagtga ttagctaacc aggtaagagg tcgggacgaa aatcctggcc
    23881 ttgtttttat tagtaaccat actttaatgc gataattgat tggacttttg tcaaggagat
    23941 gtgtatgttt gaagtagaag aatggctcca tagtcggatt ggtttaaatt ttcgatcagg
    24001 tttgggccga atgcagcaag cggtggattt gttaggaaat cctgagcagt cttaccctat
    24061 tatccacgta acagggacta atgggaaagg atctaccatt gcttttatga gggaattatt
    24121 tatggggcat ggcaaaaaag ttgcgacctt tacctcccct catatcgtct ctatcaatga
    24181 ccgaatctgc attaatgggc aacctatagc agacgcagac tttatccgtt tggctgatca
    24241 ggtcaaggag atggagaaaa cgcttctgca aactcctgac cagttgtcct tttttgaatt
    24301 gctgaccttg gttgcttttc tttattttag ggagcaagag gtggatttgg ttttattaga
    24361 agtgggaatt ggtggcttac ttgacacgac caatgtggta actggagagc ttgctgtcat
    24421 cacctccatt gggcttgatc atcaagaaac cttgggtgat agtctagaag caattgcaga
    24481 gcagaaagct ggtattttca aggctggtaa gaaggcagtg attgcgaaat tgcctccaga
    24541 agctaggctt atctgtcaga aaaaagccga atctttagct gttaaccttt atcaggcagg
    24601 tcaagatttt ttaatgctga atggtgattt ttcaagctct ttactaaatc tttcacagct
    24661 ggacataggc ttagaaggag tctatcagca ggagaatgca gccttggcgt tgcaaacttt
    24721 tcttcttttt atgggagaag gaaaggaagc tgttgatgaa caggctgtaa gaaaggcctt
    24781 ggaacagacc cattgggctg gtcgcttgga gcgtattcgc ccacagattt acttggatgg
    24841 tgctcataac ctccctgcct tgactcgctt ggttgagttt atcaaagaaa aagagcagga
    24901 aggttatcga cctcaaatcc tctttggatc cttgaaacgt aaggattatc aagggatgtt
    24961 gggttatctg actgaaaatt tacctcaagt ggaactcaag atgactggct ttgactatca
    25021 agggtctttg gacgagacag atgtaacagg ttaccatgta attccctctt accgagaatt
    25081 tatcagcagt ttcgaagaaa gggcagacgc tcaagacttg ctgttcgtaa cagggtctct
    25141 ctattttatc tcagaagtac ggggctacct gctggaccgt gagcagataa attgaccccc
    25201 ttttttgaac ttgttatact aggggaattg ctggttagag aaaatttctc taaattggta
    25261 gcagaaagga aatccatcat gaaattaaaa agattcacac tttctcttgc ttctctagca
    25321 agttttagtc tcttagtagc ttgttcacaa agagctcaac aggttcaaca gcctgctcaa
    25381 cagaatacca atactgcaaa tgcagggggt aaccaaaatc aagcggctcc agtacaaaac
    25441 caacctgttg ctcagccgac cgatattgat gggacttata ctggtcagga tgacggagac
    25501 cgtatcactt tagtggtaac tggaacgact ggtacatgga ctgagctcga atctgacggg
    25561 gatcagaaag tcaaacaggt tacatttgat tcagcaaatc aacgcatgat tattggcgat
    25621 gatgtcaaaa tttacactgt aaacggtaat caaatcgtcg tagatgatat ggatagagac
    25681 ccatcggacc aaatcgtttt aactaaataa gactatgcaa gtagaaaggg ctggattttt
    25741 cagccttttt acttttacct agaaaataat cataaatact tgccttctac cgaatacctg
    25801 cgttatacta gtatcaatta cttgttttta gcattcaaac tatcaaggag gggatatgaa
    25861 atataggaaa tttcaattat tgatgtccaa gtatggcttt agtctttcga ttatgttact
    25921 tgaactttgt cttgtttttg gtctctttct ttatttagga cgcatggctc ccattttatg
    25981 gattactgtc ctcattctac tgagtatcat cacaatcatt tcgatagtca accgtaatac
    26041 gactcctgag aataaggtaa cctggttgtt agtagccttt gtgccagtat ttggtccctt
    26101 gctctatctg atgtttggtg aaaggcgatt gtccaaaaaa gaaatcaaac aactgaagaa
    26161 gctaggctct atgcatttcc aagaagcaaa tagccagcta ctaaaagaga aattaaaaga
    26221 aagtgacaag gcagcttatg gagtcatcaa gtccttattg agtatggata ccaatgctga
    26281 catctatgat caaactgcct ctacattttt tcctaacgga gaagctatgt ggaaaaagat
    26341 ggtagaagat cttaaaaagg ctgagaaatt tattttcttg gaatattaca ttatagaaga
    26401 aggtttgatg tggaatcgca tactagatat actagagcaa aaggtagctc agggtgtaga
    26461 ggttaagatg ctctatgatg atatcggctg tatggctact ttaacaggag attatgcaca
    26521 tcgacttcgt cagctgggca tcgaggccca taaattcaat aaagttattc ctcgtttgac
    26581 agtggcttat aataacagag atcatagaaa aatattgatt gttgatggtc agatagccta
    26641 tactggtggg gtcaatctgg cagatgagta cattaaccac gtcgagagat ttggttattg
    26701 gaaggatagt ggaattcgct tagacggact agcagtaaaa gctctgacac gcttattttt
    26761 gaccacttgg tacattaatc gaggagaaat tagtgatttt gatcaatatc atttagaaaa
    26821 tcattctatc ccgagtgacg gtttaaccat tccatacgga agtggaccca agccaatttt
    26881 tcgagcgcag gtagggaaaa aagtttatca gagtttaatc aatcaagcaa cagaatcggt
    26941 ctatattacg acaccttatt tgattataga ttatgattta acagagacaa tcaaaaatgc
    27001 agctatgaga ggggtcgatg ttcgaattat caccccttac ataccagata agaagttcat
    27061 tcagttagtc acgagaggag cttatcccga ccttctttct gctggtgttc ggatttatga
    27121 gtatagtcca ggttttattc atagtaagca gatgttggta gacgaagatt ttgcggtggt
    27181 ggggacaatc aatctcgact accggagctt ggtacaccat tatgaaaatg cagtcttact
    27241 ctataaaact ccttctataa gggaaatcgc ccgagatttt cgaaatatat ttgcagattc
    27301 tcaggaagtc tatcctcatt ctatcaaaac gagctggtat caaaagcttg taaaagaaat
    27361 cgcccagcta ttcgccccta tcttataaga aatctagaac ttaggataca aaccagacct
    27421 atttttcttg tcttttacga atagaaagaa agaggagggg aattcatgct aactaaggaa
    27481 gaagtgaatg atatgattga gttcaaacag acacatttac accgctttcg ggaaattgaa
    27541 acctttgtga aactatgcaa aaaatcactc aaacagccat cgcaagctga caatcctagg
    27601 actttttgat atactaagac agataaattg aacaggagaa acgatatgag tgtgtatggt
    27661 agagtagaag aagttcataa ggagaatcgt gaacctctag aataccaaat cgaacaagaa
    27721 tcgcatcatc gtgaatcaag tcgtcttcct ttggtgaaaa ttttactatg gagtacgctt
    27781 gtaacgggga taactctagg agtgccgcta ttactcgact taatgagtgc acaagaagtg
    27841 caggattttt atgcaggttg ggcgcttcat cagacaggga agatttacag cgactattat
    27901 ggaagtcaag gtttgcttta ttatttgctg acttacgtga gtcagggcgg atttttcttt
    27961 gccatctttg agtggttagc cttggtagca ggaggatttt tcctttttag atcagcggac
    28021 accttgacag agcaaggaga ccaagctgga catctggtga ctatttttta catgctagtt
    28081 acaggtcttg cttttggtgg aggctatgcg actcttttag cgcttccttt cttattcgca
    28141 gcctttagtt tagttgcggc ttacctaagc aatccaagcc atgataaggg atttgtacgg
    28201 attgggctag ctttggcagg cggatttttc tttgctccct tatcatcgct cctgtttatt
    28261 gctgtagtga gtttaggctt gttggtcttt aaccttgggc atagacgttt tgtgcatggg
    28321 ttttatcagt ttcttgcagt ggctttaggt ttttcacttg tcttttatcc aactgcctac
    28381 tatagtgctg caacaggaag ttttggggat gcgattagtg gtattcgtta tcctattgac
    28441 agtattcgct ttgattttac ttctaaaatt ttagagaata tgttttttta tggcttgttg
    28501 tcccttggtt tgggatttgt ggtttgtatc tttttaggtc tctttcaatc caaacccttt
    28561 aaactatacg tcatttcggt tcctgcaagt cttgtggtaa ttttaggttt gattttactt
    28621 ttcttttcac aagagcctct gcacgcttct tatttgatgg tcgtcttccc tgttttccta
    28681 cttttattgg taaccaatat taagagtcaa cagagggggc gtagtgctag aagaagccga
    28741 agagaaacgc cagttagcct atggagtcgt ttcttcaaag gaaatctata tctgctagtt
    28801 tttgggtttg tctatctttt gtctgttcct tttttgatga agtttgtcct ttatccagta
    28861 ccttatcaag aacgtaatcg tcttgctgat ttggtaaaag aggagacaaa tacggaagat
    28921 gctatctatg catgggatga tactgcgact ctttatcgta agagtgagcg cttgtcgcca
    28981 tcggcgattt tgtccccgtt gcactataca gcaactgagg aaaatcgtaa taagttactt
    29041 aatgacttga aagaaaaaca acctaaggtg attgtggtaa atgacaaggt ggtagtctgg
    29101 tctgaagtgg aaacactctt aaaagaaaat taccaacaag taaagactga ttactcagag
    29161 tttaaagtct ataaaattaa ataaccaaat caatatcttg tgtattttta aaaattttag
    29221 gatttttaac acaagatatt gatttttctt tttagagtgg tataatactt tttagaaaga
    29281 acattttaga aaagagcatg cgtatgattg cactagaaga aaaaattaca attttgccaa
    29341 ctctcttcgt cgagaaacga gatgggagac gtgttgtatt tgatgtggac aagattgaca
    29401 aggctctcca caaggcggct gacaaggtta tggatgtgac acccctggtt gaaaaacgcc
    29461 tcaatgatct gactgagcga attattacag aaattcatag tcgctttcca cagggaatta
    29521 agatttacga aattcaaaat atcgtagaac atgaactcct tgaagccaaa gaatatgcgc
    29581 tggctgagga gtatattact tatcggacac agagggattt tgagcgctca aaagcgacgg
    29641 atatcaactt tagtattcat aaacttctca acaaagacca gacagttgtc aatgaaaatg
    29701 ctaataaaga cagtgatgtc tttaacactc agcgtgattt gacagcaggg attgttggga
    29761 aatcaatcgg actgcaaatg cttcctaagc acgtagccaa tgcccaccaa aagggggata
    29821 tccactatca cgatttggac tacagtccct atacccctat gaccaactgc tgtttggttg
    29881 attttaaggg tatgttggaa aatggtttta agattggaaa tgcagaggta gagagtccca
    29941 agtctatcca gactgcgaca gcacagattt ctcaaatcat tgccaacgtt gcttctagcc
    30001 agtacggtgg ctgttcagct gaccgtatcg atgaaatttt ggcgccttat gcagagaaga
    30061 actatcaaaa acatctcaaa gatgcagaag agtgggtatt gcctgaaaaa cgggaagatt
    30121 acgcttggaa gaaaacgcaa aaggacatct acgatgccat gcaatctctt gagtatgaaa
    30181 tcaatactct cttcacttca aatggacaaa caccttttac ttcgttaggt tttggtctgg
    30241 gaaccagtcg ttttgaacga gaaattcaaa aagctatttt aaacattcga atcaagggtc
    30301 ttggttcaga acaccgtacg gctatctttc ctaaacttat tttcactctg aaaagaggcc
    30361 ttaatttaga ggaaggaact cccaactacg acatcaagca gttggctctt gagtgtgcaa
    30421 ccaaacggat gtatccagat gttttatctt acgataagat tgttgacttg acaggatcct
    30481 tcaaggtgcc tatgggttgc cgttctttcc tccaaggatg gaaggatgaa aatggtgtag
    30541 aagtcaattc aggtcgcatg aatctgggtg ttgtgacggt taatctgcct cgtattgctc
    30601 ttgagtctga aggtgatatg aataagttct gggaaatctt caacgagcga atgaatatcg
    30661 cagaagatgc tcttgtttac cgtgtcgaac gcactaaaga ggcgacacca gcaaatgctc
    30721 ctattcttta tcagtacggt gcttttggcc atcgtctagg taaagaagaa agtgttgacc
    30781 agctctttaa gaatcgtcgt gcgaccgttt cgctgggcta tatcggcttg tatgaagtag
    30841 cgacagtttt ctttggtaac agctgggaaa gtaatccaga tgctaaggaa ttcacgctag
    30901 acatcattca cgatatgaaa cgccgtgtag aagagtggtc agaccaatat ggctaccatt
    30961 tctctatcta ctcaacacca tccgaaagtc tgacagaccg tttctgccga ctagatatag
    31021 acaagtttgg ctctattcct gatatcacag acaaggaata ctacaccaac tctttccact
    31081 acgatgttcg taaaaatcca acaccgtttg aaaaattgga ctttgagaaa gtctatccag
    31141 aagcaggtgc gtcaggtggt ttcatccatt attgtgagta tccagtcctt cagcaaaatc
    31201 caaaggcctt ggaagctgtc tgggattatg cttatgaccg tgtaggctat ctaggcacca
    31261 atactccgat tgaccgttgc tacaagtgtg actttgaagg ggattttgaa ccaactgaga
    31321 gagggtttgc ttgtccaaac tgtggcaata gcgatcctaa aacagtagac gttgttaaac
    31381 ggacttgtgg ctatcttggc aatcctcaag caagaccgat ggtcaacggg cgtcacaagg
    31441 aaatcgctgc gcgtgtcaaa catatgaatg gttcaacgat taaaatagct gggcatcaag
    31501 taacaaatta gaaagaaatg aaatggggaa atatcaacta gacgataagg ggcgcgcaca
    31561 agtgacccgt tatcacgaga aatactctaa aggtggagct ggtaagaaag aacgcttgct
    31621 tagcttcaga gaacaatttt taaacaagaa caagaaaaaa taaaagtgag agccagctct
    31681 cgcttttctc atagtgggag gtaaggatgg aattacgcag accaagatta gcggataaga
    31741 aagctgtttt agatatgatg acagagtttg aaaagagcca atcagcccat gatggaggat
    31801 tttgggatac agagaacttt gtgtatgaag agtggttgga aagcaatcag gaacaggaaa
    31861 tggggattaa tctgcctgaa ggatgggttc ctgcaattca gttagtggct ttttctgaga
    31921 aaggtcaagc agttggattt cttaatctcc ggttgcgcct cagtaacttt ctactagaag
    31981 aaggtgggca cattggctac tccatccgtc catctgaaag aggcaagggt tatgcaaaag
    32041 agactctccg tcagggcttg caagttgcta aggaaaagaa catcaagaaa gctctggtga
    32101 cctgtagcgt gaataatcct gctagcagag cagtcattct agcaaatggt ggaatatttg
    32161 aggatgctca caatggagtc gagcgttatt ggatagaggt agcgaatgaa taatccaaaa
    32221 ccacaagaat ggaaaagcga ggaacttagt caaggtcgta tcattgacta caaggccttt
    32281 aactttgtgg acggcgaagg cgtgcgcaac tctctctatg tatcaggctg tatgtttcac
    32341 tgcgagggat gttataatgt tgcgacttgg tcttttaatg ctggcattcc ctatacagca
    32401 gaattagaag agcagatcat ggcagacctt gcccaaccct atgttcaagg cttgactttg
    32461 ctgggagggg aaccttttct caatactggc attctcttgc ctctagttaa acgcatccga
    32521 aaggaattgt cagacaagga catttggtcc tggacgggct acacttggga agaaatgatg
    32581 ttggaaactc cagataaact ggaactctta tcattgattg acattcttgt cgatggacga
    32641 tacgatcgaa ctaagagaaa tctcatgctc cagtttcgag gttcgtccaa ccaacgaatt
    32701 atcgatgtgc aaaaatcgct caaaagtggg caagtagtga tttgggacaa gctcaatgac
    32761 ggaaaagaaa gctatgaaca ggtgaagaga gaatgaagaa aaaagactta gtagatcaac
    32821 tagtctcaga gatcgagacg gggaaagtca ggacactggg aatatacggt catggagctt
    32881 caggtaaatc aacctctgca caggaattgt accaagcttt agattctact acagtaaatt
    32941 tgctagaaac agatccctat atcacctcag gacgccatct ggtagtaccc aaggacgcgc
    33001 cgaatcaaaa ggtgacagcc ggtctgccag tggcgcatga actggagagt ttgcagagag
    33061 atatccttgc cttgcaggcg agtatggatg tcttgacaat tgaagaacct tggaaggcta
    33121 gtgaggtctt gtctggagcc aaaccaattt tgattgtcga agggatgtct gttggctttc
    33181 tacccaagga actctttgaa aaaaccatct gtttctacac ggatgaggag accgaattaa
    33241 agcgacgcct tgctagagat acgactgtga gaaatcgtga tgcatccttt atattggcta
    33301 gccatcagat gagacgggag cagtatctgc gatactataa agaaactgag tctaaggcgg
    33361 atatcttagt ggatcaatca gaagataaat ttgatgtcaa gaggacttaa cttatgtata
    33421 gaagaaatat agaagaaaat ccctaatttt agaaagaaaa agtaggaaaa cagtttcatc
    33481 ccaaaaaaac gaaaaaacct aacaaatccc ttgcaatcgc aggggatttg tgttattcta
    33541 ttatggtgct gtaaattaca gccttagttt tgatgcaaga ggttgcgaca cgctcggttg
    33601 cattgccacg caacaccgtg tcggttttct tgtggagcta gcctattatc ttaaatagac
    33661 gaaaaggaga aaaagatggc aaacaaaaaa atccgtatcc gtttgaaagc ttacgaacac
    33721 cgtacgcttg acacagcggc tgcaaaaatc gtagaatcag ctactcgtac aggtgcacaa
    33781 gttgcgggtc caatcccact tccaactgaa cgtagcctct acacaatcat tcgtgcgact
    33841 cacaaataca aagactctcg cgaacaattt gaaatgcgta cacacaaacg tttgatcgat
    33901 atcgttaacc caactcaaaa aacagttgat gccttgatga aattggatct tccaagtggt
    33961 gtaaacgtag aaatcaaact ttaatctaaa atataagaga gcagaggctg gtgtttcaat
    34021 ctaattgaac acgggctaaa cttggtgtga aaaagataaa cttcctcgcg tctgctagac
    34081 actgtgtcag tttcctattt tcacgttgag tttgacgccc tttgtatctt agacttgagc
    34141 ataaaaaacg ctcgttaaaa actttttgaa taaaaaatat agaaaaggaa ctattttctc
    34201 atgacaaaag gaatcttagg gaaaaaagtg ggaatgactc aaatcttcac tgaagctggc
    34261 gaattgatcc ctgtaacagt tattgaagca actccaaacg ttgttcttca agttaaaact
    34321 gttgaaacag acggatacaa cgctatccaa gttggtttcg atgacaaacg cgaagtattg
    34381 agcaacaaac ctgctaaagg acatgtagcg aaagctaaca cggctcctaa gcgcttcatt
    34441 cgtgaattca aaaacgttga aggcttggaa gttggtgctg aaattacagt tgaaacattc
    34501 gcagctggag acgttgttga cgtaactggt acttctaaag gtaaaggttt ccaaggtgtt
    34561 atcaaacgcc acggacaatc acgtggacca atggctcacg gttctcgtta ccaccgtcgt
    34621 ccaggttcta tgggacctgt tgcacctaac cgcgtattca aaggtaaaaa ccttgcaggg
    34681 cgtatgggtg gcgaccgcgt aacaattcaa aaccttgaag ttgtacaagt tgttccagaa
    34741 aagaacgtta tccttatcaa aggtaacgta ccaggtgcta agaaatctct tatcactatc
    34801 aaatcagcag ttaaagctgg taaataataa agaaagggga aatcagtcac aatggcaaac
    34861 gtaacattat ttgaccaaac tggtaaagaa gctggccaag ttgttcttaa cgatgcagta
    34921 tttggtatcg aaccaaatga atcagttgtg tttgatgtaa tcatcagcca acgcgcaagc
    34981 cttcgtcaag gaacacacgc tgttaaaaac cgctctgcag tatcaggtgg tggacgcaaa
    35041 ccgtggcgtc aaaaaggaac tggacgtgct cgtcaaggtt ctatccgctc accacaatgg
    35101 cgtggtggtg gtgttgtctt cggaccaact ccacgttcat acggctacaa acttccacaa
    35161 aaagttcgtc gcctagctct taaatcagtt tactctgaaa aagttgctga aaacaaattc
    35221 gtagctgtag acgctctttc atttacagct ccaaaaactg ctgaatttgc aaaagttctt
    35281 gcagcattga gcatcgattc taaagttctt gttatccttg aagaaggaaa tgaattcgca
    35341 gctctttcag ctcgtaacct tccaaacgtg aaagttgcaa ctgctacaac tgcaagtgtt
    35401 cttgacatcg caaatagcga caaacttctt gtcacacaag cagctatctc taaaatcgag
    35461 gaggttcttg cataatgaat ttgtatgatg ttatcaaaaa acctgtcatc actgaaagct
    35521 caatggctca acttgaagca ggaaaatatg tatttgaagt tgacactcgt gcacacaaac
    35581 ttttgatcaa gcaagctgtt gaagctgctt tcgaaggtgt taaagttgcc aatgttaaca
    35641 caatcaacgt aaaaccaaaa gctaaacgtg ttggacgtta cactggtttt actaacaaaa
    35701 ctaaaaaagc tatcatcaca cttacagctg attctaaagc aatcgagttg tttgctgctg
    35761 aagctgaata atctaaggag gaaatatcgt gggaattcgt gtttataaac caacaacaaa
    35821 cggtcgccgt aatatgactt ctttggattt cgctgaaatc acaacaagca ctcctgaaaa
    35881 atcattgctt gttgcattga agagcaaggc tggtcgtaac aacaacggtc gtatcacagt
    35941 tcgtcaccaa ggtggtggac acaaacgttt ctaccgtttg gttgacttca aacgtaataa
    36001 agacaacgtt gaagcagttg ttaaaacaat cgagtacgat ccaaaccgtt ctgcaaacat
    36061 cgctcttgta cactacactg acggtgtgaa agcatacatc atcgctccaa aaggtcttga
    36121 agtaggtcaa cgtatcgttt caggtccaga agcagatatc aaagtcggaa acgctcttcc
    36181 acttgctaac atcccagttg gtactttgat tcacaacatc gagttgaaac caggtcgtgg
    36241 tggtgaattg gtacgtgctg ctggtgcatc tgctcaagta ttgggttctg aaggtaaata
    36301 cgttcttgtt cgtcttcaat caggtgaagt tcgtatgatt cttggaactt gccgtgctac
    36361 agttggtgtt gtcggaaacg aacaacatgg acttgtaaac cttggtaaag caggacgtag
    36421 ccgttggaaa ggtatccgcc caacagttcg tggttctgta atgaacccta acgatcaccc
    36481 acacggtggt ggtgaaggta aagcaccagt tggtcgtaaa gcaccatcta ctccatgggg
    36541 caaacctgct cttggtctta aaactcgtaa caagaaagcg aaatctgaca aacttatcgt
    36601 tcgtcgtcgc aacgagaaat aatattaaac tagtcgctta agcaactagt aaatccgcca
    36661 gctcggtagc gctccatagg agtgcaagcc gctgtggtac aacatttaaa ggagaaaata
    36721 taaaaatggg acgcagtctt aaaaaaggac ctttcgtcga tgagcatttg atgaaaaaag
    36781 ttgaagctca agctaacgac gaaaagaaaa aagttattaa aacttggtca cgtcgttcaa
    36841 cgatcttccc aagtttcatt ggttacacta ttgcagttta tgacggacgt aaacacgtac
    36901 ctgtttacat ccaagaagac atggtaggcc acaaacttgg tgaatttgca ccaactcgta
    36961 cttacaaagg tcacgctgca gacgacaaga aaacacgtag aaaataagga gaacataaat
    37021 ggcagaaatt acttcagcta aagcaatggc tcgtacagta cgtgtttcac ctcgtaaatc
    37081 acgtcttgtt cttgataaca tccgtggtaa aagcgtagcc gatgcaatcg caatcttgac
    37141 attcactcca aacaaagctg ctgaaatcat cttgaaagtt ttgaactcag ctgtagctaa
    37201 cgctgaaaac aactttggtt tggataaagc taacttggta gtatctgaag cattcgcaaa
    37261 cgaaggacca actatgaaac gtttccgtcc acgtgcgaaa ggttcagctt caccaatcaa
    37321 caaacgtaca gctcacatca ctgtagctgt tgcagaaaaa taaggaggta aaatcgtggg
    37381 tcaaaaagta catccaattg gtatgcgtgt cggcatcatc cgtgattggg atgccaaatg
    37441 gtatgctgaa aaagaatacg cggattacct tcatgaagat cttgcaatcc gtaaattcgt
    37501 tcaaaaagaa cttgctgacg cagcagtttc aactattgaa atcgaacgcg cagtaaacaa
    37561 agttaacgtt tcacttcaca ctgctaaacc aggtatggtt atcggtaaag gtggtgctaa
    37621 cgttgatgca ctccgtgcaa aacttaacaa attgactgga aaacaagtac acatcaacat
    37681 catcgaaatc aaacaacctg atttggatgc tcaccttgta ggtgaaggaa ttgctcgtca
    37741 attggagcaa cgtgttgctt tccgtcgtgc acaaaaacaa gcaatccaac gtgcaatgcg
    37801 tgctggagct aaaggaatca aaactcaagt atcaggtcgt ttgaacggtg cagatatcgc
    37861 ccgtgctgaa ggatactctg aaggaactgt tccgcttcac acacttcgtg cagatatcga
    37921 ttacgcttgg gaagaagcag atactacata cggtaaactt ggtgttaaag tatggatcta
    37981 ccgtggtgaa gttcttccag ctcgtaaaaa cactaaagga ggtaaataac caatgttagt
    38041 acctaaacgt gttaaacacc gtcgtgaatt ccgtggaaaa atgcgcggtg aagcaaaagg
    38101 tggaaaagaa gtagcattcg gtgaatacgg tcttcaagct acaactagcc actggatcac
    38161 taaccgccaa atcgaagctg ctcgtatcgc catgactcgt tacatgaaac gtggtggtaa
    38221 agtttggatt aaaatcttcc cacacaaatc atacactgct aaagctatcg gtgtgcgtat
    38281 gggatctggt aaaggggcac ctgaaggttg ggtagcacca gttaaacgtg gtaaagtgat
    38341 gttcgaaatc gctggtgtat ctgaagagat tgcacgtgaa gcgcttcgac ttgctagcca
    38401 caaattgcca gttaaatgta aattcgtaaa acgtgaagca gaataaggag aaggcatgaa
    38461 acttaatgaa gtaaaagaat ttgttaaaga acttcgtggt ctttctcaag aagaactcgc
    38521 gaagcgcgaa aacgaattga aaaaagaatt gtttgaactt cgtttccaag ctgctactgg
    38581 tcaattggaa caaacagctc gcttgaaaga agttaaaaaa caaatcgctc gtatcaaaac
    38641 agttcaatct gaagcgaaat aatagactag ggaaggagaa atttcaatgg aacgcaataa
    38701 tcgtaaagtt cttgttggac gtgttgtatc tgacaaaatg gacaagacaa tcacagttgt
    38761 agttgaaaca aaacgtaacc acccagtcta tggtaaacgt attaactact ctaaaaaata
    38821 caaagctcat gatgaaaaca atgttgccaa agaaggcgat atcgtacgta tcatggaaac
    38881 tcgcccgctt tcagctacaa aacgtttccg tcttgtagaa gttgttgaag aagcggtcat
    38941 catctaatca aacctgaaag gagaaaactg aaatgattca aacagaaact cgtttgaaag
    39001 tcgcagacaa cagcggtgct cgcgaaatct tgactatcaa agttcttggt ggttcaggac
    39061 gtaaatttgc aaacatcggt gatgttatcg tggcatctgt aaaacaagct actcctggtg
    39121 gtgcggttaa aaaaggtgac gttgttaaag cagttatcgt tcgtactaaa tcaggtgctc
    39181 gtcgtgctga tggttcatac atcaaatttg acgaaaacgc agcagttatc atccgtgaag
    39241 acaaaactcc tcgcggaaca cgtatctttg gcccagttgc acgtgaattg cgtgaaggtg
    39301 gcttcatgaa gatcgtgtca cttgctccag aagtacttta atttttagga acaaactagt
    39361 cccctagctt caagctaggg tgcccttatg ggcgtaagaa aaatcaagga gaaacctaat
    39421 gtttgtaaaa aaaggcgaca aagttcgcgt aatcgctggt aaagataagg gaacagaagc
    39481 tgttgtcctt actgcccttc caaaagtaaa caaagttatc gttgaaggtg ttaacattgt
    39541 taagaaacac caacgtccaa ctaacgagct tcctcaaggt ggtatcatcg agaaagaagc
    39601 agctatccac gtatcaaacg ttcaagtttt ggacaaaaat ggtgtagctg gtcgtgttgg
    39661 ttacaaattt gtagacggta aaaaagttcg ctacaacaaa aaatcaggcg aagtgcttga
    39721 ttaatcacga aggaaaggag aagtataatg gcaaatcgtt taaaagaaaa atatcttaat
    39781 gaagtagttc ctgctttgac agaacaattc aactactcat cagtgatggc tgtgcctaaa
    39841 gtagataaga ttgttttgaa catgggtgtt ggtgaagctg tatcaaacgc taaaagcctt
    39901 gaaaaagctg ctgaagaatt ggcacttatc tcaggtcaaa aaccacttat cactaaagct
    39961 aaaaaatcaa tcgccggctt ccgtcttcgt gaaggtgttg cgatcggtgc aaaagttacc
    40021 cttcgtggtg aacgtatgta cgaattcttg gataaattgg tatcagtttc acttccacgt
    40081 gtacgtgact tccacggtgt cccaacaaaa tcatttgatg gacgcgggaa ctacacactt
    40141 ggtgtgaaag aacaattaat cttcccagaa atcaacttcg atgacgttga caaaactcgt
    40201 ggtcttgaca tcgttatcgt aacaactgct aacactgacg aagagtcacg tgcattgctt
    40261 acaggccttg gaatgccttt tgcaaaataa tataggaggt aaatctaatg gctaaaaaat
    40321 caatggtagc tagagaggct aaacgccaaa aaattgttga ccgttatgct gaaaaacgtg
    40381 ctgcattaaa ggcggcaggg gactacgaag gtttatctaa attacctcgc aacgcctcac
    40441 cgactcgttt acataatcgt tgtagggtta cggggcgccc acattcagtt taccgcaaat
    40501 ttggtctgag tcgtatcgct tttcgcgaac ttgcgcataa aggtcaaatt cctggtgtaa
    40561 caaaggcatc ttggtaattt aagatatcaa gagcgtcaaa actccaagta aaaataggaa
    40621 acttgacgaa gaaactaaag tttctaggaa agtttatctt tttcacacag agtttagccc
    40681 gggttcaatt gggcttgcca atttgaacac gagctacagc tttggcaaaa aagaccaatt
    40741 tgctttggag cattgcttct gcattaaatt gtctattttt gctcgtgctg ttacgctctt
    40801 tgtatcatgt attaactagc aagtgcaact tgcaaactac tagtaagagg agaaaaacaa
    40861 aatggttatg actgacccaa tcgcagactt cctaactcgt attcgtaatg ctaaccaagc
    40921 taaacacgaa gtacttgaag tacctgcatc aaacatcaaa aaagggattg ctgaaatcct
    40981 taaacgcgaa ggttttgtaa aaaacgttga aatcattgaa gatgacaaac aaggcgtcat
    41041 ccgtgtattt cttaaatacg gaccaaatgg tgagaaagtt atcactaact tgaaacgtgt
    41101 ttctaaacca ggacttcgtg tctacaaaaa acgtgaagac cttccaaaag ttcttaacgg
    41161 acttggaatt gccatccttt caacttctga aggtttgctt actgataaag aagcacgcca
    41221 aaagaatgtt ggtggtgagg ttatcgctta cgtttggtaa aatcaagata caaagctcgt
    41281 aaagaacaaa gcaaaattag gaagttggag aagtttgttt acaaacaagc caacttatct
    41341 attttgcaca gttcttagag cgtgttcagt tcagctcttg aactaaataa gtatctgaac
    41401 cccgtgaaaa ctggccgttc tggcctgaca atttaacagg agaaaataaa catgtcacgt
    41461 attggtaata aagttatcgt gttgcctgct ggtgttgaac tcgctaacaa tgacaacgtt
    41521 gtaactgtaa aaggacctaa aggagaactt actcgtgagt tctcaaaaga tattgaaatc
    41581 cgtgtggaag gtactgaagt aactcttcac cgtccaaacg attcaaaaga aatgaaaact
    41641 atccacggaa ctactcgtgc ccttttgaac aacatggttg ttggtgtatc agaaggattc
    41701 aagaaagaac ttgaaatgcg tggggttggt taccgtgcac agcttcaagg atctaaactt
    41761 gttttggctg ttggtaaatc tcatccagac gaagttgaag ctccagaagg aattactttt
    41821 gaacttccaa acccaacaac aatcgttgtt agcggaattt caaaagaagt agttggtcaa
    41881 acagctgctt acgtacgtag ccttcgttca ccagaaccat ataaaggtaa aggtatccgt
    41941 tacgttggtg aattcgttcg ccgtaaagaa ggtaaaacag gtaaataatg ttgagtggtt
    42001 gatcatcaac caccaaccta ttttccaact ttgtgcatag cacacgattt aaaactaaag
    42061 aggtgaaaac tgtgatttca aaaccagata aaaacaaact ccgccaaaaa cgccaccgtc
    42121 gcgttcgcgg aaaactctct ggaactgctg atcgcccacg tttgaacgta ttccgttcta
    42181 atacaggcat ctacgctcaa gtgattgatg acgtagcggg tgtaacgctc gcaagtgctt
    42241 caactcttga taaagaagtt tcaaaaggaa ctaaaactga acaagccgtt gctgtcggta
    42301 aactcgttgc agaacgtgca aacgctaaag gtatttcaga agtggtgttc gaccgcggtg
    42361 gatatctata tcacggacgt gtgaaagctt tggctgatgc agctcgtgaa aacggattga
    42421 aattctaata ggaggacact agaaaatggc atttaaagac aatgcagttg aattagaaga
    42481 acgcgtagtt gctgtcaacc gtgttacaaa agttgttaaa ggtggacgtc gtcttcgttt
    42541 cgcagctctt gttgttgttg gtgaccacaa tggtcgcgta ggatttggta ctggtaaagc
    42601 tcaagaagtt ccagaagcaa tccgtaaagc agtagatgat gctaagaaaa acttgatcga
    42661 agttcctatg gttggaacaa caatcccaca cgaagttctt tcagaattcg gtggagctaa
    42721 agtattgttg aaacctgctg tagaaggttc tggagttgcc gctggtggtg cagttcgtgc
    42781 cgttgtggaa ttggcaggtg tggcagatat tacatctaaa tcacttggtt ctaacactcc
    42841 aatcaacatt gttcgtgcaa ctgttgaagg tttgaaacaa ttgaaacgcg ctgaagaaat
    42901 tgctgccctt cgtggtattt cagtttctga tttggcataa gaaaggggat aaaatggctc
    42961 aaattaaaat tactttgact aagtctccaa tcggacgcat tccatcacaa cgtaaaactg
    43021 ttgtagcact tggacttggc aaattgaaca gctctgttat taaagaagat aacgctgcta
    43081 tccgtggtat gattacagca gtatctcact tagtaacagt tgaagaagta aactaatgaa
    43141 gttttagggg atgtgcactg taccatcccc taaaactaga tatagtcatc tatgatgaca
    43201 tcgtataggc gagttgatgg gggagacaac cttttctccc ttatcggcgc tagcatttta
    43261 caaaagagga gaaaataaaa atgaaacttc atgaattgaa acctgcagaa ggttctcgta
    43321 aagtacgtaa ccgcgttggt cgtggtactt catcaggtaa cggtaaaaca tctggtcgtg
    43381 gtcaaaaagg tcaaaaagct cgtagcggtg gcggagttcg ccttggtttt gaaggtggac
    43441 aaactccatt gttccgtcgt cttccaaaac gtggattcac taacatcaac gctaaagaat
    43501 acgcaattgt gaaccttgac caattgaacg tctttgaaga tggtgctgaa gtaactccag
    43561 ttgttcttat cgaagcagga attgttaaag ctgaaaagtc aggtattaaa attcttggta
    43621 acggtgagtt gactaagaaa ttgactgtga aagcagctaa attctctaaa tcagctgaag
    43681 aagctatcac tgctaaaggt ggttcagtag aagtcatcta agagaggtga cctatgtttt
    43741 ttaaattatt aagagaagct cttaaagtca agcaggttcg atcaaaaatt ttatttacaa
    43801 tttttatcgt tttggtcttt cgtatcggaa ctagcattac agttcctggt gtgaatgcca
    43861 atagcttgaa tgctttaagt ggattatcct tcttaaacat gttgagcttg gtgtcgggga
    43921 atgccctaaa aaacttttcg atttttgccc taggagttag tccctatatc accgcttcta
    43981 ttgttgtcca actcttgcaa atggatattt tacccaagtt tgtagagtgg ggtaaacaag
    44041 gggaagtagg tcgaagaaaa ttgaatcaag ctactcgtta tattgctcta gttctcgctt
    44101 ttgtgcaatc tatcgggatt acagctggtt ttaatacctt ggctggagct caattgatta
    44161 aaactgcttt aactccacaa gtttttctga cgattggtat catcttaaca gctggtagta
    44221 tgattgtcac ttggttgggt gagcaaatta cagataaggg atacggaaac ggtgtttcca
    44281 tgattatctt tgccgggatt gtttcttcaa ttccagagat gattcagggc atctatgtgg
    44341 actactttgt gaacgtccca agtagccgta tcacttcatc tatcattttc gtaatcattt
    44401 tgattattac tgtattgttg attatttact ttacaactta tgttcaacaa gcagaataca
    44461 aaattccaat ccaatatact aaggttgcac aaggtgctcc atctagctct taccttccgt
    44521 taaaggtaaa ccctgctgga gttatccctg ttatctttgc cagttcgatt actgcagcgc
    44581 ctgcggctat tcttcagttt ttgagtgcca caggtcatga ttgggcttgg gtaagggtag
    44641 cacaagagat gttggcaact acttctccaa ctggtattgc catgtatgct ttgttgatta
    44701 ttctctttac attcttctat acgtttgtac agattaatcc tgaaaaagca gcagagagcc
    44761 tacaaaagag tggtgcctat atccatggag ttcgtcctgg taaaggtaca gaagaatata
    44821 tgtctaaact tcttcgtcgt cttgcaactg ttggttccct cttccttggt gtgatttcca
    44881 ttttaccgat tgcagctaaa gatgtatttg gtctttctga tgttgttgcc tttggtggaa
    44941 caagtctctt gatcattatc tctacaggta tcgaaggaat caagcaattg gaaggttacc
    45001 tattgaaacg taagtatgtt ggttttatgg acagaacaga ataaaagtat ttactgaatc
    45061 agtaaatgct gagagagtgg aggtttaaac tctgacattt gtaagagttg gatctcccct
    45121 cttctatttt gtttttaaat aggggtgaaa agactttttg cttctattta aaaataaaat
    45181 aaggagatca aatcatgaat cttttgatta tgggcttacc tggtgcaggt aagggaactc
    45241 aagcagcaaa aatcgtagaa caattccatg ttgcacatat ctcaacaggt gatatgttcc
    45301 gcgctgcaat ggcaaatcaa actgaaatgg gtgttcttgc taagtcatat attgacaagg
    45361 gtgaattggt tcctgacgaa gttacaaatg gaatcgtaaa agaacgtctt tcacaagatg
    45421 atattaaaga aacaggattc ttattggatg gttacccacg tacaattgaa caagctcatg
    45481 ccttggacaa aacattggct gaacttggca ttgaactaga aggtgttatc aatattgaag
    45541 tgaaccctga cagccttttg gaacgtttga gtgggcgtat catccaccgc gtaactggag
    45601 aaactttcca caaggtcttt aacccaccag ttgactataa agaagaagat tactaccaac
    45661 gtgaagatga taagcctgag acagtaaaac gtcgtttgga tgttaatatt gctcaaggag
    45721 aaccaatcat tgctcactac cgtgccaaag gtttggttca tgacatcgaa ggtaatcaaa
    45781 atatcaatga tgtcttctca gatattgaaa aagtattgac aaatttgaaa taaagcgttt
    45841 ttcacacttg caaaaatccg ctacaaatgt tatactgaga tagtctgact tataattgtt
    45901 gtctctgtgt ctagaggcat cgaatcgaaa tttatggagg tgcttttgcg tggcaaaaga
    45961 cgatgtgatt gaagttgaag gcaaagtagt tgatacaatg ccgaatgcaa tgtttacggt
    46021 tgaacttgaa aatggacatc agattttagc aacagtttct ggtaaaattc gtaaaaacta
    46081 tattcgtatt ttagcgggag atcgtgttac tgtcgaaatg agtccatatg acttgacacg
    46141 tggacgtatc acttaccgct ttaaataatc gaaaaacttg gagggataag aaatgaaagt
    46201 aagaccatcg gtcaaaccaa tttgcgaata ctgtaaagtt attcgtcgta atggtcgtgt
    46261 tatggtaatt tgcccagcaa atccaaaaca caaacaacgt caaggataag atagaaagga
    46321 gaaaacatgg ctcgtattgc tggagttgat attccaaatg acaaacgcgt agtaatctca
    46381 ttgacttatg tttatggtat cggacttgca acatctaaga aaattttggc tgctgctgga
    46441 atctcagaag atgttcgtgt acgtgatctt acatcagatc aagaagatgc tatccgtcgt
    46501 gaagtggatg caatcaaagt tgaaggtgac cttcgtcgtg aagtaaactt gaacatcaaa
    46561 cgtttgatgg aaatcggttc ataccgtggt atccgtcacc gtcgtggact tcctgtccgt
    46621 ggacaaaaca ctaaaaacaa cgctcgcact cgtaaaggta aagctgttgc gattgctggt
    46681 aagaaaaaat aatataggag gtaaaagtct tggctaaacc aacacgtaaa cgtcgtgtga
    46741 aaaagaatat cgaatctggt attgctcata ttcacgctac atttaataac actattgtta
    46801 tgattactga tgtgcatggt aatgcaattg cttggtcatc agctggtgct cttggtttca
    46861 aaggttctcg taaatctaca ccattcgctg ctcaaatggc ttctgaagct gctgctaaat
    46921 ctgcacaaga acacggtctt aaatcagttg aagttactgt aaaaggtcca ggttctggtc
    46981 gtgagtcagc tattcgtgcg cttgctgccg ctggtcttga agtaacagca attcgtgatg
    47041 tgactccagt gccacacaat ggtgctcgtc ctccaaaacg tcgccgtgta taatcatcgc
    47101 attacactgc ttttcgttta agagggagta actaaatgat cgagtttgaa aaaccaaata
    47161 taacaaaaat tgatgaaaat aaagattatg gcaagtttgt aatcgaacca cttgaacgtg
    47221 gctacggtac aactcttggt aactctcttc gtcgtgtact tctagcttct ctaccaggag
    47281 cagctgtgac atctatcaac attgatggtg tgttacatga gtttgacaca gttccaggtg
    47341 ttcgtgaaga cgtgatgcaa atcattctga acattaaagg aattgcagtg aaatcgtacg
    47401 ttgaagacga aaaaatcatc gaactggatg ttgaaggtcc tgctgaagta acagctggtg
    47461 acattttgac agatagcgat attgaaattg taaatccaga tcattatctc tttacaatcg
    47521 gtgaaggttc ttctctaaaa gcgactatga ctgttaacag tggtcgtgga tatgtacctg
    47581 ctgatgaaaa taaaaaggat aatgcaccag ttggaacact tgctgtagat tctatttata
    47641 caccagttac aaaagtcaac tatcaagtgg aacctgctcg tgtaggtagc aatgatggtt
    47701 tcgacaaatt aacccttgaa atcttgacaa atggaacaat tattccagaa gatgctttag
    47761 ggctttcagc acgtattttg acagaacatc ttgatttgtt tacaaatctt actgagattg
    47821 ctaagtcaac tgaagtgatg aaagaagctg atactgaatc tgacgaccgt attttagatc
    47881 gtacgattga ggaactggac ttgtctgtgc gttcatacaa ctgtttaaaa cgtgccggta
    47941 tcaatactgt gcatgatttg acagaaaaat ctgaagcaga gatgatgaaa gtacgaaatc
    48001 ttggacgcaa gagtttggaa gaagtgaaac tcaaactcat tgatttgggt cttggattaa
    48061 aagataaata aaggaggaat acatggctta ccgtaaacta ggacgcacta gctcacaacg
    48121 taaagcaatg cttcgcgatt tgacaactga ccttttgatc aacgaatcaa tcgtgacaac
    48181 tgaagctcgt gctaaagaga tccgtaaaac tgttgaaaaa atgattactc taggtaaacg
    48241 tggtgatttg catgcacgtc gtcaagcagc tgctttcgta cgtaatgaaa tcgcatctga
    48301 aaactatgat gaagcaactg ataagtacac ttctactaca gcacttcaaa aattgttctc
    48361 agaaatcgca cctcgttatg ctgaacgtaa cggtggatac actcgtatcc ttaaaactga
    48421 accacgtcgt ggtgatgcag cgccaatggc gatcatcgaa ttagtataaa atcatcaatt
    48481 ttgttgagtg ttatgatgat ggagtcttgt gctcttagtc tagctctggt ctaccgctag
    48541 gatttcggtc ctagcgggaa cactcatcat aagttgggat agtagacgct tgtttacgaa
    48601 attgtttttt tcttaagaac aacttcgtaa gcaggcgttt ttgagtattt tcgttagaat
    48661 tatgctatac tatttgaaaa gaatcctgtt taatgttaag gtttcttatt ttaagaagaa
    48721 ttggagttta cttatgaaag ccattataac tgttgttggt aaagataaat ctggaattgt
    48781 tgcaggtgtt tctggtaaaa ttgcagaatt aggattgaat attgacgata tctctcaaac
    48841 tgtcttggat gaatatttta cgatgatggc tgttgtatct agtgatgaaa agcaagattt
    48901 tacctatctt cgtaatgaat ttgaagcttt tgggcaaact ttgaatgtaa aaatcaatat
    48961 tcagagtgca gcgattttcg aagctatgta taatatctag gaggtcatca tggatattag
    49021 acaagttact gaaaccatcg ccatgattga ggagcaaaac ttcgatatta gaaccattac
    49081 catggggatt tctcttttgg actgtatcga tccagatatc aatcgtgctg cggagaaaat
    49141 ctatcaaaaa attacgacaa aggcggctaa tttagtagct gttggtgatg aaattgcggc
    49201 tgagttggga attcctatcg ttaataagcg tgtatcggtg acacctattt ctctgattgg
    49261 ggcagcgaca gatgcgacgg actacgtggt tctggcaaaa gcgcttgata aggctgcgaa
    49321 agagattggt gtggacttta ttggtggttt ttctgcctta gtacaaaaag gttatcaaaa
    49381 gggagatgag attctcatca attccattcc tcgcgctttg gctgagacgg ataaggtctg
    49441 ctcgtcagtc aatatcggct caaccaagtc tggtattaat atgacggctg tggcagatat
    49501 gggacgaatt atcaaggaaa cagcaaatct ttcagatatg ggagtggcca agttggttgt
    49561 attcgctaat gctgttgagg acaatccatt tatggagggt gcctttcatg gtgttgggga
    49621 agcagatgtt atcatcaatg tcggagtttc tggtcctggt gttgtgaaac gtgctttgga
    49681 aaaagttcgt ggacagagct ttgatgtagt agccgaaaca gttaagaaaa ctgcctttaa
    49741 aatcactcgt atcggtcaat tggttggtca aatggccagt gagagactgg gtgtggagtt
    49801 tggtattgtg gacttgagtt tggcaccaac ccctgcggtt ggagactctg tggcacgtgt
    49861 ccttgaggaa atggggctag aaacagttgg cacgcatgga acgacggctg ccttggccct
    49921 cttgaacgac caagttaaaa agggtggagt gatggcctgc aaccaagtcg gtggtttatc
    49981 tggtgccttt atccctgttt ctgaggatga aggaatgatt gctgcagtgc aaaatggctc
    50041 tcttaattta gaaaaactag aagctatgac ggctatctgt tctgttggat tggatatgat
    50101 tgccatccca gaagatacgc ctgctgaaac cattgcggct atgattgcgg atgaagcagc
    50161 aatcggtgtt atcaacatga aaacaacagc tgttcgtatc attcccaaag gaaaagaagg
    50221 cgatatgatt gagtttggtg gtctattagg aactgcaccc gttatgaagg ttaatggggc
    50281 ttcgtctgtc gacttcatct ctcgcggtgg acaaatccca gcaccaattc atagttttaa
    50341 aaattaagaa aataggagaa attttaagtt ctatttaaga ttagatgtgt atactataat
    50401 cattaaataa agacctccta atattatttg aaacagataa cactgaatta gtttgaattt
    50461 gattttcatc taatatcttt atttaatgaa ctcctaaact ttttcataat aatctccttc
    50521 aaaagtcgcc tgtatgggtg gcttttattt tatcattcat gatataatag aagcaaacgg
    50581 aggacggaaa atggtaaaag tacgattgta tttggtacgt catggcaaga ccatgtttaa
    50641 cacgattggt cgcgcgcaag gttggagcga tactccctta actgctgaag gtgaacgagg
    50701 gattcaagag ttaggaatcg gtttgcgaga atctgatcta cagtttgagc gcgcttattc
    50761 gagtgattct ggtcgtacca ttcagaccat gggaattata cttgaagaac ttggcttgca
    50821 ggggaaaatc ccttatcgca tggacaagcg tatcagagaa tggtgtttcg gtagttttga
    50881 tggagcctat gatggcgatc ttttcatggg cattattcct cgtatcttta atgtggacca
    50941 cgttcaccaa ttgtcttatg ctgaactggc tgagggcttg gtagaggtcg atacagctgg
    51001 ttgggctgaa ggttgggaaa aactcagtgg ccgaatcaag gaaggctttg aaataattgc
    51061 aaaagaaatg gaagatcaag gtggaggtaa cgcccttgtt gtcagccatg gaatgactat
    51121 tggaaccatt gtttatctga ttaatggcat gcatccgcat ggtctagata atggtagcgt
    51181 gacgattctt gaatatgagg acggtcagtt tagggttgaa gttgtcggtg accgtagtta
    51241 ccgagagcta ggacgtgaga agatggaaga aggctctatt taatcagtct agacttgctt
    51301 gccatgagct agggatttga taagaatatc aagataagaa aaaacagccg agggtactcc
    51361 tttcggctgt ttttgatgtg gaaaactaaa gtgtaatgct attgctttta gagattttca
    51421 taaacaagag caaggaacct actgttagaa cagtcaggat agttgacaag gctgcggcta
    51481 caccgtaatt tcctctgaga acctctgtat aaatagctac agtcattgtt cttgttttga
    51541 cattgtagag gaggatagag gatagaagta gagagttctg aaatcagtgt gacccaagat
    51601 aggatggctc cagaaataat acccgatagc atcattggag ttgtaatctt agcaaaggta
    51661 ttgagacgac tacttcctaa gctttcagca gcttcttcaa tacttggtgc tatttgttgt
    51721 aagctagcaa cagatgagcg aatagtatac ggtaatcttc tgacagatag agacataatc
    51781 aagatgaaag cagtccctgt aatcataaga aatccacttc caaatagacc agtattgaag
    51841 gaagaaatga aggcaatccc tagaacggtt cctggtacaa tataaggtac catactgagg
    51901 ctgtcaatta agtttgtaaa caaattccgt tttctaacgg ctaggtagga gataaatgtc
    51961 gcaaatagaa caactagaac taaggcaatc aaagggatac gaatggtatt gaaaatagca
    52021 gatcccatac gattgaaagc tagcttgtaa ctgtttggag aataaccttt aaaaaatacc
    52081 atacctgatg tttttaggaa agaggtataa attaagtaga tttgaggtaa aacagagata
    52141 aagataattc cgtagactgt tgcataaatg gcagccattt ttccttttgt agttttttta
    52201 ggctcaattg gatggagcag attcatgctg aaactgtagc ggtttgcaat gtgtttttgg
    52261 ataaggaaaa ttgccaaggc aatgataatc gccataattg caaaagcaga atttcctcca
    52321 acctcgctaa taaattgggt ataaatcagg acagggaaag tccgatatcc ttcgccaatc
    52381 aacataggcg ttccaaagtc tgagaatgct ctcataaata caagcaagga gctgctagta
    52441 aggttggaac tagaagaggt aaaacaaccg ttacgatagg tttaaatccg aaggacccca
    52501 tgctttcagc tgcttcaagt agagaattgt caatactgtt cattgttcca gcaacatata
    52561 gaaataccag tgggaatagt tgcagtgtaa agacaagtac aattcctttg aatccataaa
    52621 tatcgatagc tggaagatga agggcatttg tcaaaaattt agtgatgacc ccatttcgtc
    52681 ccagcaagag aacccaggag taggctccta cgaaaggagc tgacatggaa gcaatgataa
    52741 tcaatatttg tagaaatttc ttccccttga agtcatacat agagaagaga taagctaata
    52801 gggttcctac aactaaggaa gtgacagtag cggtaatgga aaccctgaaa ctgttgacta
    52861 gtgtctcaga gtagtaggct ttactaaaga aagtgacaaa attagctagt gagaattgtc
    52921 cttcatgtat aagtgcttgc ttgagcacgg taatgatagg ataaacgaga aagacaagat
    52981 aggtaagaaa gaggaagaaa gaggaggctg tccaaatatt tagtttttta cgttccatgg
    53041 ttgactcctt ttatcaggtt ttgggaacca tctgcagaaa agatgtttaa tttttgcgta
    53101 ttgattcgta gacgaatacg attgcctttt tgtagttctt cttcaaaagt tgattcttca
    53161 ctaacttgaa tttttgaggc aaaacctgtc tcaatgaaat actccgtatt tagtccaaga
    53221 tagacgctat cgctaatagt tccttcaata tctccagatt catctttgat aaactcttcg
    53281 ggacgaatgc ttacatgaat agcttgctcc tcaacctgat caagagctgg cattcgaagg
    53341 gcatagccat ctgaaaagac gatataagcg ccgtcgctcc gtttttcaag attggcaggg
    53401 ataatatttg tgcgtccgat aaaggttgcc acaaactcat tagctggttt atgatagagt
    53461 tcttttggtc ggccgatttg ttggatcacc ccatctttca taacagcaat ttgatctgaa
    53521 atagccatgg cttcttcttg gtcgtgggtt acataaacag ttgtaattcc cacttcgtgt
    53581 tggatttctc ggatggcttg acgcatatcc aagcgaagtt tggcctccag attactaagt
    53641 ggctcgtcca tgaggagaac acttggatta accgctaagg cgcatgccaa ggtgacacgt
    53701 tgttgttgtc caccactgag tttatcgggc tttcgatccg catattgagc aatttgcatg
    53761 agttcaagat acttgttggt ctgttgaatc aattcttctt ttggaacctt cttttgctta
    53821 agaccaaaag caacgttgtc tcggacagtc aaatgtggga aaatagcgta gttttggaaa
    53881 accatcccga tattgcgttt gctgggttcc atattattga tttttgtatc atcgaagtaa
    53941 aattctccat ctttgatact gttgaaacct gcaatcatac gaagaagggt cgttttccca
    54001 catcctgaag gtccaagaag ggtaaagaga cttccttttg gaattgtaat gttcaaattc
    54061 tcaataacag ggacatcgtg gtagattttt tggcgttaat aattttgatc tcactcatag
    54121 tgaacctttt ttactgttta gattggatat ctgtaaagac ttcgttgtat ttcttaacga
    54181 tatctgattt attcttgatg acataatcat aatcttcagt gagtgttttg attttgtcaa
    54241 ttggtttcat gttttcgctt gttttagcat ttttacgaac aggacggtta gtagtggttg
    54301 taccaagtgt atcttgtact tcttgagaga taataaaatc gataaatttc ttgtcatttt
    54361 ccatattttt agctttttta acgatagcag cactagcagg taggaagacg gttccttctt
    54421 ttggatagac tactttaatg ttagctccgt catttaagag tttaactgct ggatcctcat
    54481 aagagagacc aacagccatt tctccatcaa cgactgcttt atagacacca gatgaacttg
    54541 aaccgatttt atagtgtatt gaaactagaa tagtacacct ctacttctaa aacattgtta
    54601 gaaatcgatt tgactgtcct gattaatttg tcctgttctt atttcatttc actatgccat
    54661 caataagtgt gaaaagatct tttacataag accaagcctt atcatctttg taaccacctt
    54721 gagcttgtag catatttgtt aattgagcaa aggcgctaga agagtttgct gggtcagcag
    54781 ttgcgatttt ttcttttagt tcaggtttga gaagatcgtt atatccttcg atgttcatgc
    54841 ctttagttaa atcagggtgg acgattaaaa cactaccatc tagtgtataa ggagtagaga
    54901 agccagttgt gttttgatat tctttgataa cattatcatt ttcttttgaa gtatagtttt
    54961 caaagagttc tccgtgggta gtatattgtg tataagaacc accaaagata acatcagcta
    55021 caggaacttc tttttctgac tctagttttt tgaaaagttc tccagtacca gcttgaatca
    55081 gttctacttt gataccatat ttttcttcaa aggcaggaat agttgctcca attaagccct
    55141 ctgagtttgg tgaataaacg actagcgaac cgccgtctcc tttatcagat gaactgtcat
    55201 cggcagattc attagaagaa caagcagcat aatacatcca tttctttttc atgatggata
    55261 cctccgttgt gttatttaag tttattttaa aacaatgtaa gcgtttttaa aacatacaat
    55321 tctattctat agtgtattga atctataaca gtacactttg actgctaaaa tatttctata
    55381 aattaatttg actttcctga tagagatgtt cacatcttat ttcaattcac tatattagag
    55441 taaaattctc tacaaaaaga agaatagcct attttactat tcttctgagt gatttcaatt
    55501 cctttgggga aatatggaga tactttttaa atcctgacaa atggttgttt ctttttctaa
    55561 atcggtgata ctgtatcgga gaatgcgcgt gaggtcacaa aggctgcgat agagcttcta
    55621 tggagaattt ctttttggag agatttttta aaggaatgag acatccgcta cctccttgga
    55681 aggttttttt gtgataagta tagcagttta aaaattctag agcaaggtaa aatagaaaag
    55741 gtttggctaa aattttttag ctaaaccttt tgaaaagtta agtatgtatt atagatgctt
    55801 gttatctgca aatagctaga gcatttcaag gaaataaact agaaataaca attaatatgg
    55861 tggttcagaa ataccttttg ataatcaata agatcttcag gatgaagtgc gttgattcca
    55921 tccatttcat atttccgatt taataaacga tatttgtttt caccaaattg atgaaaaggg
    55981 agtagttgaa cttggtcgat atttaatgag ttaaatagag tagcgaattt ttctgcatcc
    56041 tctaaactat tgttaaaatt aggaataact gggattctta aaacgatagt tttattttgt
    56101 gaaaaagcat aatgaatgtt tttaataatc atttgattaa aaaccccagt cactttttta
    56161 tgttttatag aattataatg ttttaggtct gtgtagataa aatccacata ttgaattaaa
    56221 tcaataaatt tttcatgatc aacaaaggca gtagtttcaa tggcagtgtg tatgtgatgt
    56281 tctttagctg attttaagat ggctttagca aattcaaact gagcaaatat ttcacctcct
    56341 gataaagtta aacctccacc ggattcttcg taaaattctt tgtcttttaa tacctctgta
    56401 ataatttctt ctacagtctt ttcttcaccg actaaggtga atttctctcg ttgagcatct
    56461 ttcatttttt caggtttcat tctttgagat tcaggattag aacaccatgg acagcgcaga
    56521 ggacatcctt ttaaaaaaac agttgtacga atacccgggc cgtcatgaat tgaaaagtgt
    56581 tgaatattaa aaataattcc tttagatatt tccataagag ttcctcctct tcataagtct
    56641 atcctatcac aaaaacgaaa gaaaaacaat tacgaacgaa aggttaattt attgtttttt
    56701 gctttttatt ttggtagaat aaaacggagg tgtaaaatga aaagattgga acaaattatt
    56761 aaattagtat cagaatatga aaagatcgac gttaatacat tatcggaaaa attaaatgta
    56821 tcgaaagtaa cgattagaaa agatttagat aaattagagt caaaaggttt attacacaga
    56881 gagcatggat atgctgtatt aaatagtgga gatgacttaa atgtacgttt gtcaattaat
    56941 tatgaaatta agagaaaaat tgttcaggaa gcagtaaaat tggtgtcaga taatgaaaca
    57001 ataatgatag aatctggatc gacctgtgct ttacttgctg aggaaatttg caagcaaaaa
    57061 agaaatgtta cgattgtaac aaattcattt tttatagcaa attttgtgag agcttatgat
    57121 tcatgtcgta ttattgttct tggtggagag tttcagaagg attcacaggt tactgtggga
    57181 cctttattaa aagaaatgat acagactttt catgtgcatc aagcttttgt tgggacagat
    57241 ggttacgata aagagatggg ctttacagga aaagatttaa tgcgcagtga ggtagttcaa
    57301 tatatttcag cagcgtcgga taaagtcatt gtactaactg actcaagtaa atttgataaa
    57361 aggggtacag taagaagatt tgctttaagt caagtctatg aagtaataac agacgaaaaa
    57421 ctttctaaac aaaatatagc tacattagaa aatgctggga taatggttaa ggtagtttcg
    57481 taagaggtta agtgtatgaa tcaagatagg aataaactgc tctctaaaat tgcttatctg
    57541 tattatattg aaaacttaaa tcagtcacaa atagcagcaa aattaggaat ttatagaacc
    57601 tctattagta gaatgttaac agaagcaagg aatgcaggaa ttgttaaaat tgaaatagag
    57661 aattttgata ccaatatgtt taagttggaa aattatgtaa aagaaaaata tggtctggaa
    57721 agtttagaaa ttattccaaa tgaatttgat gataatccaa caattttatc tgaaagaatt
    57781 tctcaagttg cagcaggtgt ccttaggaat ctaattgatg ataatatgaa aattggcttt
    57841 tcttggggga aaagtttaag taatttagta gatttaattc acagtaaaag tgtccgaaat
    57901 gttcacttct atcctctagc aggtggtcct agtcacatac acgctaaata ccatgtgaat
    57961 acactgattt atgaaatgtc tagaaaattt catggagagt gtacatttat gaatgcaacg
    58021 attgtgcaag aaaataaatt gttagcagat ggtattttgc aatcaagata ttttgaaaat
    58081 ttgaaaaata gttggaaaga tttagatata gctgtagtcg gaattggtga ttttagcaat
    58141 aaaggaaagc atcaatggtt agacatgctt acagaggatg actttaaaga attgaccaaa
    58201 gttaaaactg taggagaaat ttgttgtcga ttttttgatt caaaaggtaa agaagtctat
    58261 gaaaacttac aggaaagaac gatagcaatc tctttggaag atttaaaaaa tattcctcaa
    58321 agtttagctg ttgcttacgg tgatacgaaa gtatcttcga ttctttctgt cttgcgtgct
    58381 aatttagtaa atcatttgat tacagacaaa aatacaattt taaaagtttt ggaagaagat
    58441 ggggatttga cttttagaga gattctaggt gagtgaaaat gatagactga ttcagtttat
    58501 catttttctt tttagttgat tgcacatttg tgcttatata aacaaaaata gtttatctgt
    58561 tgtttttgga ttgacaactt tattatgtag ttgtattcta tagttacaaa agaaaatttt
    58621 aaaatttcaa atgaaaaaag ctttttacat agtgaaatga ggaggaattt atggaaatta
    58681 ttgttccaga tcaaattatc atgggtttaa ttttatatgc tggcgatgcg aaacaacata
    58741 tttataaagc attagattac ataaagaacg gtacatgtga acgatgtgaa gaagaaatcc
    58801 agttagctga tgcagcctta ttagaagctc ataatctaca aacaaaattc ttggcacagg
    58861 aagcgtctgg tacaaagaca gaaattacag ctctctttgt tcattcacaa gatcatctca
    58921 tgactagtat gacggagatt aatttaatca aagaaattat tagtttgaga aaagaacttc
    58981 ataaaaaata atactagagt attatcattg ttattaacat agaggaggaa aacataatgg
    59041 tgaagattgg tttgttttgt gcagcaggtt tttctactgg tatgcttgta aataatatga
    59101 aaattgcagc gcaatctagt ggagttgagg cagaaataga ggcgttttct cagtctaaat
    59161 tagcggatta tgcgccaaat atagatgttg cactattggg tccacaagtt gcttatacat
    59221 tagataaatc aaaagaaatt tgtgataagt gtgatgttcc gatagctgtt attccgatga
    59281 tggactatgg tatgttagat gggaaaaaag tattagattt ggccctatct ttgattagtg
    59341 ggtaagaaaa ggagatttat tatgtcaaag atggatgttc agaaaatcat tgcaccgatg
    59401 atgaagtttg tgaatatgcg tggcattata gctctaaaag atgggatgtt agcaattttg
    59461 ccattgacag tagttggtag tttgttcttg attatgggac aattgccgtt cgaaggatta
    59521 aataagagca ttgctagtgt ttttggagct aattggacag agccgtttat gcaagtatat
    59581 tcaggaactt ttgctattat gggtctaatt tcttgttttt caattgccta ttcttatgct
    59641 aagaatagcg gagtagaggc tttaccagct ggagttctat ctgtatctgc attctttatt
    59701 ttgctaagat catcttatat ccctaaacaa ggtgaggcga ttggggacgc tattagtaaa
    59761 gtttggtttg gaggccaagg aattatcggt gctatcatta taggtttggt agtaggaagt
    59821 atttatacct tctttataaa gagaaaaatt gttattaaga tgccagaaca agttccacaa
    59881 gctattgcga aacagtttga agcaatgatt ccagcatttg taattttctt atcttctatg
    59941 attgtatata ttttagcgaa gtcattgact aatggcggaa cattcataga aatgatttat
    60001 tctgctattc aagttccgtt gcaaggttta actggatctt tgtatggtgc tattggaatt
    60061 gcattcttta tatcattttt gtggtggttt ggtgttcatg ggcaatcggt agtaaatgga
    60121 gtagtgacag ctctgctttt atctaatctt gatgctaata aagctatgtt agcctctggt
    60181 aatctatcat tagaaaatgg tgcacatatt gttactcaac aatttttaga ttcattttta
    60241 attctatcag gttcagggat tacgtttggt cttgtagttg ccatgctttt tgcagcaaaa
    60301 tcaaaacaat accaagcctt aggaaaagtt gcagcttttc cagcaatatt taacgtaaat
    60361 gagccagttg tatttggatt tccgattgtc atgaatccag ttatgtttgt acctttcatt
    60421 cttgttcctg tacttgcagc tgtgatagta tatggagcta ttgcaacagg tttcatgcag
    60481 ccattctcag gggtaacatt gccttggagt acaccagcta ttctatcagg atttttggtg
    60541 ggtggatggc aaggtgttgt gactcagtta ttagtattgg tgatatctac agtggtttac
    60601 tttccattct ttaagataca agatcgttta gcttaccaaa atgaaatcaa acaatcttag
    60661 aggtatttgt gtgttactgt taaactcaca catttgtgct aaaaattaga gagttaaaat
    60721 ttttctagtt aaaagcttga aaatttctat aaaaatcggt attatatttt cgaaagaaat
    60781 aaaaatattt tcgaaagaaa ggtgcttacg atggtaaata cagaagtagc aagaacaaca
    60841 atcaagacag aatattttgg cagccttact gaaaggatga acaaatatcg agaagatgtt
    60901 ttaaataaaa aaccttatat tgatgctgag agagcagttc tagcaacacg cgcctatgaa
    60961 cgatacaagg aacaacctaa tgtcctaaaa cgtgcatata tgctgaaaga aattttggaa
    61021 aatatgtcta tctatattga agaagaatct atgattgcgg gaaatcaagc ttcttccaat
    61081 aaagatgctc ctatttttcc ggaatatacg ctagaatttg ttctcaatga gttggatctt
    61141 tttgaaaagc gtgatggaga tgttttctat attacagaag aaacaaaaga acaacttaga
    61201 agtattgctc cgttttggga aaataataat ttacgtgcta gagctggtgc cttattacct
    61261 gaagaagtgt ctgtttatat ggaaacagga ttcttcggta tggaaggtaa gatgaattct
    61321 ggagatgctc acttagcagt taactatcag aaacttttgc aatttggttt aagaggtttt
    61381 gaagagcggg ctcgtaaagc aaaagtagct ctagatttaa cagatccagc aagtattgat
    61441 aaatatcatt tttacgactc tatatttatc gtaatcgatg ctattaaagt atatgcaaag
    61501 cgctttgttg ctcttgctaa aagtttagcc gaaaatgcaa atcctaaacg taagaaagaa
    61561 ttacttgaga ttgcagatat ttgctctaga gtcccatatg aaccggcaac tacttttgca
    61621 gaagctattc aatcagtttg gtttattcaa tgtattttac aaattgaatc taatggccac
    61681 tctctttcat atggccgttt tgatcaatat atgtatccat atatgaaggc tgatttagaa
    61741 agtggtaaag aaacagaaga tagcattgtt gaacgtctga caaatctttg gattaagaca
    61801 attacaatta ataaggttcg cagtcaatca catacatttt cttcagcagg aagtccttta
    61861 tatcaaaatg ttacaattgg tggacagact cgagataaga aggatgctgt taacccatta
    61921 tcttatttgg tattaaaatc agttgcacaa acccatctac cgcaacctaa tctaactgta
    61981 cgttaccatg caggtttaga tgctcgtttc atgaatgagt gtattgaagt gatgaaactt
    62041 ggttttggta tgcctgcatt taataatgat gagattatta ttccttcttt tattgcaaaa
    62101 ggagtattgg aagatgatgc ttatgattac agtgccattg gatgtgttga aacggcagtt
    62161 ccagggaaat ggggctatcg ttgcacaggt atgagttata tgaacttccc taaggttcta
    62221 cttatcacga tgaatgatgg aattgatccg gcttcgggta aacggtttgc accaagcttt
    62281 ggtcatttta aggatatgaa gaacttttct gaattagaaa atgcttggga taaaacacta
    62341 agatatttga cacgaatgag tgttattgtt gaaaattcta ttgatttatc attggaacga
    62401 gaagttcctg atattctatg ttcagcattg actgatgatt gtattggtcg tggaaaacac
    62461 cttaaagaag gtggagcagt atatgattat atatcaggat tgcaagttgg aattgcaaat
    62521 ttgtcggatt cgttagctgc aattaaaaaa ttggtgtttg aggaagaacg tataagccca
    62581 agtcaacttt ggcatgcact ggaaacagat tatgccggag aagaaggtaa ggtcattcaa
    62641 gaaatgttga ttcatgatgc acctaagtat ggtaatgatg atgattatgc tgacaaattg
    62701 gttactgctg cttatgacat ttatgttgat gaaattgcta aatatcctaa tacacgttat
    62761 ggaagagggc ctattggagg aattcgttat tcaggaacat cttctatatc agccaacgta
    62821 gggcagggac gtggaacatt agcaactcca gatggacgca acgcgggtac accgttagca
    62881 gagggttgtt caccatcaca taatatggat caacacggcc ctacatctgt tttaaaatct
    62941 gtttcaaaat taccaacaga tgaaatcgta ggtggggttc tcttaaatca gaaagtaaat
    63001 cctcaaacgt tagccaaaga agaagataaa ttaaaactaa ttgctttgtt acgaacattc
    63061 tttaatcgtt tacatgggta ccatattcaa tacaatgttg tttccagaga gacgttgatt
    63121 gacgctcaga aacatcctga aaaacacaga gacttaattg ttcgtgttgc aggatactct
    63181 gcattcttca atgttctttc taaggcaacc caagatgaca ttataggacg tactgagcat
    63241 actttgtaaa ataaagaggt tctttttatg gaatttatgc ttgacacatt aaatttagat
    63301 gagattaaaa agtggtctga aattttgccg ctagctgggg taacttcaaa tcccactatt
    63361 gcaaaaagag agggttctat taattttttt gaacgaatca aagatgtaag agaattgatt
    63421 ggctctacac cctctattca tgttcaggtg atttctcaag attttgaagg catcttaaag
    63481 gatgctcatg aaattcgaag acaagcagga gatgatatat ttatcaaagt acctgttact
    63541 ccagctggat tacgtgcaat aaaggtgcta aaaaaagagg gctaccatat cactgcaaca
    63601 gctatttata cagttattca gggattatta gctatcgaag taggagcgga ttacctagct
    63661 ccatattata atagaatgga aaatctgaac attgattcaa attctgtcat tcgtcaatta
    63721 gctcttgcta ttgatagaca gaactctcct agtaagattt tagctgcatc ctttaaaaat
    63781 gtagcacaag taaataatgc tttagctgca ggtgcgcatg ctgttacagc aggagcggat
    63841 gtttttgaat cagctttcgc catgccatct atccaaaagg cggttgatga tttttctgac
    63901 gattggtttg ttattcaaaa tagtcgttcc atttagatag agaggaaata catatgagaa
    63961 tttttgctag tccttctaga tatattcagg gggaaaatgc cttgtttgaa aatgccaaat
    64021 caattttgga tttgggaaat tgccctattc tattatgcga tcagttggtt tatgatattg
    64081 ttggaaaacg atttgaagat tacctacata ggtatggttt ccatattgtt ctggcgctat
    64141 ttaatggtga agcttctgac aatgaaatca atcgagttgt tgccttggct gagaaagaaa
    64201 attgtgatag tattatcggt cttggtgggg gaaagacgat tgatagcgca aaagctattg
    64261 cagatttgat tgaaaagcct gttattattg ctccaacaat tgcatcgacc gacgcacctg
    64321 tatctgcttt atctgttatt tatacagatg aaggtgcatt tgatcattat ctattttatt
    64381 ctaaaaatcc agatttagtt ttggttgata caaaagttat ttcacaagcc cctaagcgtt
    64441 tattagcgtc tggtattgca gatggtttag caacttgggt tgaggcgcgt gcggttatgc
    64501 aggcaaatgg aaaaactatg ttgggacaac agcaaacatt ggctggagtt gcaattgcga
    64561 agaaatgtga agaaacgctg tttgcagatg gtttacaggc tatggcagct tgtgaagcta
    64621 aagtggtgac accagcatta gaaaatattg ttgaagctaa tactttattg agtggtctag
    64681 gttttgaaag tggaggatta gctgcggcgc atgcaattca taatggtttt actgcattga
    64741 caggtgacat tcatcattta acacatggtg aaaaagtagc ttatggaact ttagtacaac
    64801 tattattgga aaatagacct aaagaagaac ttgataagta tattgagttt tacaaaaaaa
    64861 ttggtatgcc aacaactcta aaagaaatgc atttggatca agttggatat gatgatttaa
    64921 taaaagttgg taaacaagca actatggagg gtgagacaat tcatcagatg ccgtttaaga
    64981 tttcgccttc agatgttgct caagctatta tcgctgtaga tgcctatgta aattcaaaat
    65041 aaacaataag gactactgtt ttccaaatgg tagtctttta ttgatccctg tattgaattc
    65101 tatagaagat tgaaatagga tgagaacaaa tcgattggga aagtaaaatt aatttctata
    65161 aatgttttag caattgtttc gtactatttc agattcagtc tactatatgt tcttcataaa
    65221 tcaaaaagcg acataggttg tcggctattt attgtgaata cattaattag cattccagtt
    65281 ttatcttcgg tctaaaataa gtattttgtg ctatacgaga taagcttctt gacttactcc
    65341 ttgatttact gcataacaat gggataaaaa gtgggagata gagcaattca tagtcatcaa
    65401 aattaatgag atacagtata cagtttttcc tttaaacaca tttcaaattc cctcaaaaat
    65461 ggtataatag taacatcaca aaattggaga gagaccatga gtttttacaa tcataaagaa
    65521 attgagccta agtggcaggg ctactgggca gaacatcata catttaagac aggaacagat
    65581 gcatcaaaac ctaagtttta tgcgcttgat atgttccctt atccgtctgg agctggtctg
    65641 cacgtaggac acccagaagg ttatactgca accgatatcc tcagtcgtta caaacgtgcg
    65701 caaggctaca atgtccttca cccaatgggt tgggatgctt ttggtttgcc tgcagagcaa
    65761 tacgctatgg atactggtaa tgacccagca gaatttacag cggaaaacat tgccaacttc
    65821 aaacgtcaaa ttaatgcgct tggattttct tatgactggg atcgtgaagt caacacaaca
    65881 gatccaaact actacaagtg gactcaatgg attttcacca agctttacga aaaaggcttg
    65941 gcctatgaag ctgaagtgcc agtaaactgg gttgaggaat tgggaactgc cattgccaat
    66001 gaagaagtgc ttcctgacgg aacttctgag cgtggaggct atccagttgt ccgcaaacca
    66061 atgcgccaat ggatgctcaa aatcacggct tacgcagagc gcttgctcaa tgacttagat
    66121 gaactagatt ggtcagagtc tatcaaggat atgcaacgca actggattgg taaatcaact
    66181 ggtgccaatg taactttcaa agtaaaagga acagacaagg aatttacagt ctttactact
    66241 cgtccggaca cacttttcgg tgcgactttc actgtcttgg ctcctgaaca tgaattagta
    66301 gacgctatca caagttcaga gcaagcagaa gctgtagcag actataaaca ccaagccagc
    66361 cttaagtctg acttggctcg tacagacctt gctaaagaaa aaacaggggt ttggactggt
    66421 gcttatgcca tcaaccctgt caatggtaag gaaatgccaa tctggattgc agactatgtc
    66481 cttgctagtt atggaacagg tgcggttatg gctgtgcctg cccacgacca acgtgactgg
    66541 gaatttgcca aacaatttga ccttccaatc gtcgaagtac ttgaaggtgg aaatgtcgaa
    66601 gaagctgcct acacagagga tggcctgcat gtcaattcag acttcctaga tggactcaac
    66661 aaagaagacg ctattgccaa gattgtggct tggttggaag aaaaaggctg tggtcaggag
    66721 aaggttacct accgtctccg cgactggctc tttagccgtc aacgttactg gggtgagcca
    66781 attccaatca ttcattggga agatggaact tcaacagctg ttcctgaaac tgaattgccg
    66841 cttgtcttgc ctgtaaccaa ggatatccgt ccttcaggta ctggtgaaag tccactagct
    66901 aacttgacag attggcttga agtgactcgt gaagatggtg tcaaaggtcg tcgtgaaacc
    66961 aacactatgc cacaatgggc tggttcaagc tggtactacc tccgctatat tgatccacac
    67021 aatactgaga agttggctga tgaggacctc ctcaaacaat ggttgccagt agatatctac
    67081 gtgggtggtg cagagcatgc tgttcttcac ttgctttacg ctcgtttctg gcacaaattc
    67141 ctctatgacc tcgatgttgt tccgactaag gaaccattcc aaaaactctt taaccaaggg
    67201 atgattttgg gaacaagcta ccgtgaccac cgtggtgctc ttgtggcaac cgacaaggtt
    67261 gaaaaacgtg atggttcctt cttccatgta gaaacagggg aagagttgga gcaagcgcca
    67321 gccaagatgt ctaaatcgct caagaacgtt gttaacccag acgatgtggt ggaacaatac
    67381 ggtgccgata cccttcgtgt ttatgaaatg tttatgggac cactcgatgc ttcgattgct
    67441 tggtcagaag aaggtttgga aggaagccgt aagttccttg accgagttta ccgtttgatt
    67501 acaagtaaag aaatccttgc ggaaaacaat ggtgctcttg acaaggttta caacgaaaca
    67561 gtcaaagctg ttactgagca aattgagtct ctcaaattca acacagctat tgcccaactt
    67621 atggtctttg tcaatgctgc taacaaggaa gataagcttt atgttgacta tgccaaaggc
    67681 tttattcaat tgattgcacc atttgcacct cacttggcag aagaactctg gcaaacagtc
    67741 gcagaaacag gtgagtcaat ctcttatgta gcttggccaa cttgggacga aagcaaattg
    67801 gttgaagatg aaattgaaat tgtcgtccaa atcaaaggaa aagttcgtgc caaactcatg
    67861 gttgctaaag atctatcacg tgaagaatta caagaaatcg ctttagctga tgaaaaagtc
    67921 aaagcagaaa ttgacggtaa ggaaatcgtg aaagtaattg cggtaccgaa taaactcgtt
    67981 aatatcgtcg ttaaataacg agtttattag ctctatctgc caccttcaat agtccactgg
    68041 actattgaag ccaactaaat tagttaacat tgttgtgaaa taaaaagaag taactctaga
    68101 gtatgaactt tagagttact tttagaatag gtcagaatga atagattagt gaacgatagc
    68161 aggaagtgtg aaattttatt atttaagatt tctattattg tagtgtcagt tatagtatta
    68221 gtaatgtcaa tagtgggtgc atattatttt aaaaattgtc tttgggacaa ggaaagttta
    68281 aatttgacac tcactttaga cactctcttt gcagttttta ttactttctt tagtttttca
    68341 aatgataaat caagcaatat ttttggaata tctccaaatg aaattataag gacacagtct
    68401 gaagtgtatc aatttttatt tacaaaatct tttgcaactc tattaatagt gacaaatttg
    68461 ttatccatta ttcattattt tggagccaaa aatttaatag tttcttttaa tgaaacttat
    68521 cctcgtattc aatccagtgt tggtatcatg tggctaccac tgtttggtat tctgataatc
    68581 tattttattt ggctcttaat agagggatta aaatatatca gaaaaataaa ttatattatt
    68641 caaaataggg aaataatcta tttttattcg caggtaaaag ttgtagataa acttactgat
    68701 tctgaatcga aaaaatacgg tgaatatatt gatttgtacg aatcgtgtcg tcagaacaat
    68761 ttaagtgttc tacttaactt tcttcaaaat tcggatgata aacgaggagt tattgctagt
    68821 aactcagtga gaattatgtt tgaatctttg gataaagcag accaaattgc ggccctgaat
    68881 atttgtagaa actatgtagc acgagaaaat gttttaaata aagaagatgc agaaaaattg
    68941 ttaaatgaaa ttgataaaaa acttgaaatt agcagatagg acaattcaaa tagagttgag
    69001 taaaaagttt gaaaagtgaa acaaggagaa agctatgcca gtaaatgaat atggtcagat
    69061 gattggtgag tcaatggaag gttatacacc cggtgcactg ccttctattg atttcttaga
    69121 agggcgttat gctaggatag aggctctctc ggtagaaaaa catgcggagg atttgctagc
    69181 tgtttatggc ccggatactc ctcgggagat gtggacctat ctttttcagg agccagtagc
    69241 agatatgggg gagctggtta gccttttaaa tcagatgttg gctcgtaagg accgttttta
    69301 ctatgcaatc atagacaagg cgactggtaa ggctttggga actttttctc tcatgcgcat
    69361 tgaccagaat aaccgagtaa tagaagtcgg agcagtcact ttttctccag agctaagggg
    69421 tacacggata ggaactgagg ctcagtatct cctagctcgc tatatttttg aggagctaaa
    69481 ctatcgtcgc tacgagtgga aatgcgatgc cttaaatctg ccatccagac gagttgcgga
    69541 gcgtttggga tttgtctatg aaggaacctt ccgccaggcg gtggtttata aggggcgtac
    69601 gagagatacg gattggttgt ctatgattga tatggactgg cctcaagtca aagatcgttt
    69661 ggaaacatgg ctgcgtcctg aaaattttga taaaaatgga cagcagtaca agagcttgag
    69721 agaactttaa gaggtgttga gatgattact attaaaaagc aagaaattgt caagctagag
    69781 gatgttttgc atctctatca ggctgtcggt tggacaaatt atacccatca accagagatg
    69841 ctggagcatg ccttatcgca ttcattagta atttatctgg cacttgatgg tgatgctgtg
    69901 gtgggcttga ttcgtttggt tggagatgga ttctcatcag tttttgtaca ggatttgatt
    69961 gttttaccaa tctatcagcg tcaagggatt ggtagtgccc taatgaaaga ggccttaaaa
    70021 gattacaaag atgcttatca agtccagcta gtgacagaag agacagaaaa aaacgtggga
    70081 ttttatcgtt ctatgggctt tgaaatctta tccacctata attgtatagg gatgacttgg
    70141 gcgaatcgag aaaaataaca aaacttgttt tttcttaagc aaaatttaag gatggtctag
    70201 tattatataa tcattaaata aagacctcct aactttattt aataaaatcc taaacttttt
    70261 tcatcacaat ctcctaatga agccacccaa tcaggtggct tttttgcgtg gtgaggtgct
    70321 ggtgatagaa attttttgca aaatagtaaa attttagaaa agttaaggta gttttaagtt
    70381 tcgtcttgta tcatgtagtt attaaataaa gacctcctaa ctttatttaa taaaatccta
    70441 aacttttctt tttcataata atctccctta actccaccca atcaggtgga gttttttagc
    70501 tctatttcag gcttttgggg actattctaa aaataatttt tcgatatttt tcggtatttt
    70561 tcggattttg gtcggggaat tggcggggac ttttttagcg aatataacta agaaataggt
    70621 ctgtggtcgc ttcagctagt tcaaactcaa tttgattgta agtgactgtt aattgaagaa
    70681 ctggaactac tgtaataatg attttgcttg tctagtagtg gcgtattaaa tgagaagtga
    70741 catgtaagat tgtctcttcg tttacgaaat caaaatttct atgaaattga tagaatccct
    70801 aacgttctct taatcttaac cgtcttgtcg tacagcggtt gaagaaaatg taaacctttg
    70861 acaaaattcg tgaactatgg gataataaaa aggaattgag tactagttct atatcatagg
    70921 ctagaaaaga ccccaagctc acgaccaaat aagcttgagg tcttttttga cactatttgt
    70981 ccttgtttag ccatttatcg actatacgaa gaacgacacc gaccacaatt ggtccgatga
    71041 tagttttgag tactaattcc atcatgggct atctcacctc ctttcgtagg cggtgtagca
    71101 gtgtcgtaga atattatacc acataagtgc taaacttagg agtcacccaa tcaggtggct
    71161 tttttgtttg tggcttggtt ttttgatata atagagccat gagtagaatt ttagataatg
    71221 agataatggg ggatgaggag ttagtagaac gcacgctccg tcctcagtat ttacgtgaat
    71281 atatcggaca ggataaggtc aaggaccagc tacaaatctt tattgaagct gccaaaatgc
    71341 gggatgaagc gctggatcat gtgctcttat ttgggcctcc aggtctcggg aaaacgacca
    71401 tggcctttgt tattgccaac gaactgggag tcaatcttaa gcagacgtcg ggtccagtca
    71461 ttgaaaaagc cggagatctg gtagctattt tgaatgagtt agagcctggg gatgtacttt
    71521 ttattgatga gatccatcgt ttgccaatgt cagtggaaga ggtgctttat agtgctatgg
    71581 aggacttcta catcgatatt atgattgggg ctggtgaggg tagtcgtagt gttcatttgg
    71641 agttaccacc ttttaccttg attggtgcga cgactcgggc tggtatgctc tccaatccgc
    71701 tacgggcacg ttttgggatt acaggtcata tggagtatta tgctcatgct gatttgacag
    71761 aaattgtcga gcggacggca gatatttttg agatggaaat cacccatgag gcagcatctg
    71821 agttggccct acgtagtcgt gggacccctc gtattgccaa tcgtctcctc aagcgcgtgc
    71881 gcgattttgc ccagataatg gggaatgggg ttatcgatga tgttattacc gataaggctt
    71941 tgactatgct ggatgttgac catgaaggtt tggactatgt ggatcaaaaa atccttcgca
    72001 ccatgattga gatgtacggt ggtggccctg tcggattagg aactctttct gtgaatattg
    72061 ccgaggagcg tgagactgta gaagacatgt atgagcctta cttgattcaa aaaggtttta
    72121 tcatgcggac acggtctgga cgggtggcga ctgctaaggc atatgagcac ttaggttatg
    72181 aatacagtga aaaataagca agaaatctta gaggctttta gagaaaatcc agatatgatg
    72241 gccattctga cgatcatccg agaccttggt ctgaaagact cgtggttggc agcaggttct
    72301 gtcagaaatt tcatttggaa tcttttgtca gacaaatccc cttttgatca tgaaacagat
    72361 atagatgtga ttttctttga tccagatttt tcttatgagg aaaccttatt actggagaaa
    72421 aagctgcgag aggattttcc tcagtaccag tgggaattga aaaatcaggt ctatatgcat
    72481 cagcacagtc ctcacactgc ttcctatacc agttctcgtg atgctatgag taagtatcca
    72541 gaacggtgta cgacagttgg actgcgcttg aatgaagaat cagattttga actctatgca
    72601 ccttatggtt tggaggatat tttgaatttt caagttcgtc caactcctca tttcttagaa
    72661 aatgaagacc gaatggaact ctatcaaaca cgtttatcca agaaaaattg gcaggagaaa
    72721 tggaaaaatt tgatttttaa aaatacttaa ggaaacttta agctagggag tgtacactaa
    72781 gttcataagt taagaagacc ttaacttaaa ctcctaaaac tttttcataa taatctccct
    72841 ataaaaataa agtcgcccaa tcaggcggct tatttttttg aaaaatgggc ttggtgcctg
    72901 agaataaata gcttagtgat agaagaaaat ggggaaatat ggtataatga aacgatagat
    72961 ttttgaatag gaataagatc atgtttggat tttttaagaa agataaggct gtggaagtag
    73021 aggttccgac acaggttcct gctcatatcg gcatcatcat ggatggcaat ggccgttggg
    73081 ctaaaaaacg tatgcaaccg cgagtttttg gacataaggc gggcatggaa gcattgcaaa
    73141 ccgtgaccaa ggcagccaac aaactgggcg tcaaggttat tacggtctat gctttttcta
    73201 cggaaaactg gacccgtcca gatcaggaag tcaagtttat catgaacttg ccagtagagt
    73261 tttatgataa ttatgtcccg gaactacatg cgaataatgt taagattcaa atgattgggg
    73321 agacagaccg cctgcctaag caaacctttg aagctttaac caaggctgag gaattgacta
    73381 agaacaacac aggattgatt cttaattttg ctcttaacta tggtggacgt gctgagatta
    73441 cacaggcgct taagttgatt tcccaggatg ttttagatgc caaaatcaac ccaggtgaca
    73501 tcacagagga attgattggc aactatctct ttacccagca tttgcctaag tacttacgag
    73561 acccagactt gattatccgt actagtggag aattacgttt gagcaatttc cttccatggc
    73621 agggagccta tagtgagctt tattttacgg acaccttatg gcctgatttt gacgaagtgg
    73681 ccttgcagga agctattctt gcctataatc gtcgtcatcg ccgatttgga ggagtttagg
    73741 aggaaatatg acccaggatt tacagaaaag aaccttgttt gcagggattg ccctggctat
    73801 tttcctacca attttaatga ttgggggcct cttgcttcag atagcaatcg gaatcatagc
    73861 catgctagcc atgcatgaac ttttgaagat gagaggtcta gagaccatga cgatggaggg
    73921 cctcttgacc ctctttgcaa cctttgcatt gaccattccc ttggagaatt acctgacttt
    73981 tttgccagtt gatgggaatg tggttgccta tagtgttttg atttcaatca tgttaggaac
    74041 gaccgttttt agcaagtctt atacgattga ggatgcggtt ttccctcttg ctatgagctt
    74101 ctacgtgggc tttggattta atgctttact agatgctcgt gttgcaggtt tggacaaggc
    74161 tctcttagcc ttgtgtatcg tctgggcgac agacagtggt gcctatcttg ttgggatgaa
    74221 ctatgggaaa cgaaagttag caccaagggt atcgcctaat aaaacccttg agggtgcctt
    74281 gggtggtatt ttaggagcaa ttttagtaac cattatcttt atgatagttg acagtacagt
    74341 tgctcttcca tatggaattt acaagatgtc agtctttgct attttcttta gcattgctgg
    74401 acaatttggt gatttactag aaagttcgat caaacgtcat tttggtgtta aggattctgg
    74461 gaaatttatc cctggacatg gtggtgtttt ggatcgtttc gatagtatgt tgcttgtatt
    74521 tccaatcatg cacttatttg gactctttta atcaaaagac ggaggaaacg ctatgctcgg
    74581 aattttaacc tttattctgg ttttcgggat tattgtagtg gtgcacgagt tcgggcactt
    74641 ctactttgcc aagaaatcag ggattttagt acgtgaattt gccatcggta tgggacctaa
    74701 aatttttgct cacattggca aggatggaac ggcctatacc attcgaatct tgcctctggg
    74761 tggctatgtc cgcatggccg gttggggtga tgatacaact gaaatcaaga caggaacgcc
    74821 tgttagtttg acacttgctg atgatggtaa ggttaaacgc atcaatctct caggtaaaaa
    74881 attggatcaa acagccctcc ctatgcaggt gacccagttt gattttgaag acaagctctt
    74941 tatcaaagga ttggttctgg aagaagaaaa aacatttgca gtggatcacg atgcaacggt
    75001 tgtggaagca gatggtactg aggttcggat tgcaccttta gatgttcaat atcaaaatgc
    75061 gactatctgg ggcaaactga ttaccaattt tgcaggtcct atgaacaatt ttatcttagg
    75121 tgtcgttgtt ttttgggttt taatctttat gcagggtggt gtcagagatg ttgataccaa
    75181 tcagttccat atcatgcccc aaggtgcctt ggccaaggta ggagtaccag aaacggcaca
    75241 aattaccaag attggctcac atgaggttag caactgggaa agcttgatcc aagctgtgga
    75301 aacagaaacc aaagataaga cggcaccgac tttggatgtg actatttctg aaaaggggag
    75361 tgacaaacaa gtcactgtta cacccgaaga tagtcaaggt cgttaccttc taggtgttca
    75421 accgggggtt aagtcagatt ttctatccat gtttgtaggt ggttttacaa ctgctgctga
    75481 ctcagctctc cgaattctct cagctctgaa aaatctgatt ttccaaccgg atttgaacaa
    75541 gttgggtgga cctgttgcta tctttaaggc aagtagtgat gctgctaaaa atggaattga
    75601 gaatatcttg tacttcttgg caatgatttc catcaatatt gggattttta atcttattcc
    75661 gattccagcc ttggatggtg gtaagattgt gctcaatatc ctagaagcca tccgccgcaa
    75721 accattgaaa caagaaattg aaacctatgt caccttggcc ggagtggtca tcatggttgt
    75781 cttgatgatt gctgtgactt ggaatgacat tatgcgactc ttttttagat aatcgaggaa
    75841 tattatgaaa caaagtaaaa tgcctatccc aacgcttcgc gaaatgccaa gcgatgctca
    75901 agttatcagc catgctctta tgttgcgtgc tggttatgtt cgccaagttt cagcaggtgt
    75961 ttattcttat ctaccacttg ccaaccgtgt gattgaaaaa gctaaaaaca tcatgcgcca
    76021 agaattcgaa aagattggtg ctgttgagat gttggctcca gcccttctta gtgcagaatt
    76081 gtggcgtgaa tcaggtcgtt acgaaaccta tggtgaagac ctttacaaac taaaaaaccg
    76141 tgaaaaatca gactttatct taggtccaac tcacgaagaa acctttacag ctattgtccg
    76201 tgattctgtt aaatcttaca agcaattgcc actcaacctt tatcaaattc agcccaagta
    76261 tcgtgatgaa aaacgcccgc gtaatggact tcttcgtaca cgtgagttta tcatgaagga
    76321 tgcttatagt ttccacgcta actatgatag tttggatagt gtttatgatg agtacaaagc
    76381 agcttatgag cgtattttca ctcgtagtgg tttagacttc aaggctatta ttggtgacgg
    76441 tggagccatg ggtggtaagg atagccaaga atttatggcc attacatctg ctcgtacaga
    76501 ccttgaccgc tgggttgtct tggacaagtc agttgcctca tttgacgaaa ttcctgcaga
    76561 agtgcaagaa gaaatcaagg cagaattgct caaatggata gtctctggtg aagataccat
    76621 tgcttactca agtgagtcta gctatgcagc taacttagaa atggcaacaa acgagtacaa
    76681 accaagcaac cgtgttgtcg ctgaagaaga agttactcgt gttgcaacgc cagatgttaa
    76741 atcaattgat gaagttgcag ccttcctcaa tgttccagaa gaacaaacga ttaaaaccct
    76801 cttctacatt gcagatggtg agcttgttgc agcccttcta gttggaaatg accaactcaa
    76861 cgaagtcaag ttgaaaaacc acttaggagc agatttcttt gacgttgcta gcgaagaaga
    76921 agtggcgaat gttgttcaag caggatttgg ttcacttgga ccagttggtt tgccagagaa
    76981 tattaaaatt attgcagatc gtaaggtgca agatgttcgc aatgcagttg tcggtgctaa
    77041 cgaagatggc taccacttga ctggtgtgaa cccaggccgt gattttactg cagaatatgt
    77101 ggatatccgt gaagttcgtg agggtgaaat ttccccagat ggacaaggtg tccttaactt
    77161 tgcgcgtggt attgagatcg gtcatatttt caaactcgga actcgctatt cagcaagcat
    77221 gggagcagat gtcttggatg aaaatggtcg tgctgtgcca atcatcatgg gatgttacgg
    77281 tatcggtgtc agccgtcttc tttcagcagt gatggagcaa cacgctcgcc tctttgttaa
    77341 caaaacgcca aaaggtgaat accgttacgc ttggggaatc aatttcccta aagaattggc
    77401 accatttgat gtgcatttga ttactgtcaa tgtcaaggat gaagaagcgc aagccttgac
    77461 agaaaaactt gaagcaagct tgatgggagc tggttatgaa gtcttgacag atgaccgtaa
    77521 cgaacgtgtc ggtgttaaat ttagcgatag tgacttgatt ggtcttccaa tccgtatcac
    77581 tgttggtaaa aaagcggccg atggcattgt agaagttaag atcaaggcaa ctggtgacac
    77641 cattgaggtt catgcagata acgtgcttga aacgcttgaa atcctaagca agaaataaaa
    77701 actataatca gaagaaaaac aaggaaaaaa tgtaactagt tttta
//
LOCUS       DBERXF010000005        70057 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.05, whole genome shotgun sequence.
ACCESSION   DBERXF010000005 DBERXF010000000
VERSION     DBERXF010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 70057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70057
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.05"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..154)
                     /locus_tag="ACL8JK_000357"
                     /pseudo
     CDS             complement(1..154)
                     /locus_tag="ACL8JK_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(427..1116)
                     /gene="rplA"
                     /locus_tag="ACL8JK_000358"
     CDS             complement(427..1116)
                     /gene="rplA"
                     /locus_tag="ACL8JK_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGS1785305.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1324..1749)
                     /gene="rplK"
                     /locus_tag="ACL8JK_000359"
     CDS             complement(1324..1749)
                     /gene="rplK"
                     /locus_tag="ACL8JK_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGS1785306.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            1872..2018
                     /locus_tag="ACL8JK_000360"
     CDS             1872..2018
                     /locus_tag="ACL8JK_000360"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785307.1"
                     /translation="MYSMKIKEQTRKLAAGCSKYSFEVADKTDEVSSKHCFEVVNRTD
                     AVSR"
     gene            complement(2058..2774)
                     /gene="ldcB"
                     /locus_tag="ACL8JK_000361"
     CDS             complement(2058..2774)
                     /gene="ldcB"
                     /locus_tag="ACL8JK_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HGS1785308.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2777..3247)
                     /locus_tag="ACL8JK_000362"
     CDS             complement(2777..3247)
                     /locus_tag="ACL8JK_000362"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGS1785309.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLKKETRLRFLEEMSLVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     RGDMNGHGLKGCGPVWWVPFEEMTAETCQVKPEEIKRLVECLSSEVDKLLEIKE"
     gene            complement(3249..4286)
                     /locus_tag="ACL8JK_000363"
     CDS             complement(3249..4286)
                     /locus_tag="ACL8JK_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGS1785310.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGEKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRIYMEEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVTLA
                     KNQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(4384..5709)
                     /gene="brnQ"
                     /locus_tag="ACL8JK_000364"
     CDS             complement(4384..5709)
                     /gene="brnQ"
                     /locus_tag="ACL8JK_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGS1785311.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5880..6167)
                     /locus_tag="ACL8JK_000365"
                     /pseudo
     CDS             complement(5880..6167)
                     /locus_tag="ACL8JK_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(6327..6905)
                     /locus_tag="ACL8JK_000366"
     CDS             complement(6327..6905)
                     /locus_tag="ACL8JK_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HGS1785312.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6959..8359)
                     /gene="pepV"
                     /locus_tag="ACL8JK_000367"
     CDS             complement(6959..8359)
                     /gene="pepV"
                     /locus_tag="ACL8JK_000367"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGS1785313.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8372..8977)
                     /locus_tag="ACL8JK_000368"
     CDS             complement(8372..8977)
                     /locus_tag="ACL8JK_000368"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGS1785314.1"
                     /translation="MKFLELNKKRHATKHFTDKLVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYSEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            9148..9942
                     /locus_tag="ACL8JK_000369"
     CDS             9148..9942
                     /locus_tag="ACL8JK_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1785315.1"
                     /translation="MKKFSLLLAILPFLVACENQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQLQ"
     gene            complement(10124..10957)
                     /locus_tag="ACL8JK_000370"
     CDS             complement(10124..10957)
                     /locus_tag="ACL8JK_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS1785316.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(10947..12791)
                     /gene="uvrC"
                     /locus_tag="ACL8JK_000371"
     CDS             complement(10947..12791)
                     /gene="uvrC"
                     /locus_tag="ACL8JK_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGS1785317.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVLNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(12831..13532)
                     /locus_tag="ACL8JK_000372"
     CDS             complement(12831..13532)
                     /locus_tag="ACL8JK_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
                     /protein_id="HGS1785318.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13611..14843)
                     /gene="murN"
                     /locus_tag="ACL8JK_000373"
     CDS             complement(13611..14843)
                     /gene="murN"
                     /locus_tag="ACL8JK_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HGS1785319.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQDLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEEKLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14848..16068)
                     /gene="murM"
                     /locus_tag="ACL8JK_000374"
     CDS             complement(14848..16068)
                     /gene="murM"
                     /locus_tag="ACL8JK_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HGS1785320.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMIWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16180..16959)
                     /locus_tag="ACL8JK_000375"
     CDS             complement(16180..16959)
                     /locus_tag="ACL8JK_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS1785321.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17028..18689)
                     /locus_tag="ACL8JK_000376"
     CDS             complement(17028..18689)
                     /locus_tag="ACL8JK_000376"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGS1785322.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18864..21086)
                     /gene="recJ"
                     /locus_tag="ACL8JK_000377"
     CDS             complement(18864..21086)
                     /gene="recJ"
                     /locus_tag="ACL8JK_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGS1785323.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQNQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21363..22121
                     /locus_tag="ACL8JK_000378"
     CDS             21363..22121
                     /locus_tag="ACL8JK_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1785324.1"
                     /translation="MALVEFKNVEKYYGDYHAFRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLETVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKAVLENVT
                     LAPIEVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            22161..22925
                     /locus_tag="ACL8JK_000379"
     CDS             22161..22925
                     /locus_tag="ACL8JK_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGS1785325.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDTFSVDRSILSGYTSKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22938..23615
                     /locus_tag="ACL8JK_000380"
     CDS             22938..23615
                     /locus_tag="ACL8JK_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1785326.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAVGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23625..24284
                     /locus_tag="ACL8JK_000381"
     CDS             23625..24284
                     /locus_tag="ACL8JK_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1785327.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVT
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24542..25732
                     /locus_tag="ACL8JK_000382"
     CDS             24542..25732
                     /locus_tag="ACL8JK_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HGS1785328.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHSLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKTSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26053..26934)
                     /locus_tag="ACL8JK_000383"
     CDS             complement(26053..26934)
                     /locus_tag="ACL8JK_000383"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGS1785329.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFFADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27075..28403)
                     /gene="vncS"
                     /locus_tag="ACL8JK_000384"
     CDS             complement(27075..28403)
                     /gene="vncS"
                     /locus_tag="ACL8JK_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HGS1785330.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENSLTFFIDFPKVVQD"
     gene            complement(28400..29056)
                     /gene="vncR"
                     /locus_tag="ACL8JK_000385"
     CDS             complement(28400..29056)
                     /gene="vncR"
                     /locus_tag="ACL8JK_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HGS1785331.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29105..29188)
                     /gene="pep27"
                     /locus_tag="ACL8JK_000386"
     CDS             complement(29105..29188)
                     /gene="pep27"
                     /locus_tag="ACL8JK_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HGS1785332.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(29368..30747)
                     /gene="vex3"
                     /locus_tag="ACL8JK_000387"
     CDS             complement(29368..30747)
                     /gene="vex3"
                     /locus_tag="ACL8JK_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HGS1785333.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30799..31446)
                     /gene="vex2"
                     /locus_tag="ACL8JK_000388"
     CDS             complement(30799..31446)
                     /gene="vex2"
                     /locus_tag="ACL8JK_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HGS1785334.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31459..32736)
                     /locus_tag="ACL8JK_000389"
     CDS             complement(31459..32736)
                     /locus_tag="ACL8JK_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1785335.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(33093..33263)
                     /locus_tag="ACL8JK_000390"
                     /pseudo
     CDS             complement(33093..33263)
                     /locus_tag="ACL8JK_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
     gene            complement(33406..34005)
                     /locus_tag="ACL8JK_000391"
     CDS             complement(33406..34005)
                     /locus_tag="ACL8JK_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785336.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            complement(34142..35026)
                     /locus_tag="ACL8JK_000392"
     CDS             complement(34142..35026)
                     /locus_tag="ACL8JK_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1785337.1"
                     /translation="MREKELQDWFPDARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVTDILSDMIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(35030..35416)
                     /locus_tag="ACL8JK_000393"
     CDS             complement(35030..35416)
                     /locus_tag="ACL8JK_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGS1785338.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(35409..36752)
                     /gene="cysS"
                     /locus_tag="ACL8JK_000394"
     CDS             complement(35409..36752)
                     /gene="cysS"
                     /locus_tag="ACL8JK_000394"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGS1785339.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(36834..37718)
                     /locus_tag="ACL8JK_000395"
     CDS             complement(36834..37718)
                     /locus_tag="ACL8JK_000395"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1785340.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSTNT
                     NYLYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(37730..38347)
                     /gene="cysE"
                     /locus_tag="ACL8JK_000396"
     CDS             complement(37730..38347)
                     /gene="cysE"
                     /locus_tag="ACL8JK_000396"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HGS1785341.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(38363..40576)
                     /gene="pnp"
                     /locus_tag="ACL8JK_000397"
     CDS             complement(38363..40576)
                     /gene="pnp"
                     /locus_tag="ACL8JK_000397"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGS1785342.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDYKPKKEFTETSKDSE"
     gene            40810..41079
                     /locus_tag="ACL8JK_000398"
     CDS             40810..41079
                     /locus_tag="ACL8JK_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine methyltransferase"
                     /protein_id="HGS1785343.1"
                     /translation="MLGSLSFFLRNETKIQLLKILSRQATQRKIGNRTTERLLLGRFI
                     FFHRVVGKFSFQDTSLERFNTKVSKAFTLIAIGRLAKCFTNSLVK"
     gene            complement(41261..42127)
                     /gene="metF"
                     /locus_tag="ACL8JK_000399"
     CDS             complement(41261..42127)
                     /gene="metF"
                     /locus_tag="ACL8JK_000399"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HGS1785344.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIELIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDIAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(42191..44440)
                     /gene="metE"
                     /locus_tag="ACL8JK_000400"
     CDS             complement(42191..44440)
                     /gene="metE"
                     /locus_tag="ACL8JK_000400"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGS1785345.1"
                     /translation="MSTTIVGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVSAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLTVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEVILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(44700..44966)
                     /locus_tag="ACL8JK_000401"
     CDS             complement(44700..44966)
                     /locus_tag="ACL8JK_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1785346.1"
                     /translation="MEGCLSELFSKEEILESDMRVAIMSELIEARNKQGISQKKLEEV
                     SGVSQPVIARMETGKTSPQLDTVLKVLASLGKTLAVVPLEQGKS"
     gene            complement(45051..45540)
                     /locus_tag="ACL8JK_000402"
                     /pseudo
     CDS             complement(45051..45540)
                     /locus_tag="ACL8JK_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            45696..46696
                     /locus_tag="ACL8JK_000403"
                     /pseudo
     CDS             45696..46696
                     /locus_tag="ACL8JK_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
     gene            complement(46764..49169)
                     /gene="pheT"
                     /locus_tag="ACL8JK_000404"
     CDS             complement(46764..49169)
                     /gene="pheT"
                     /locus_tag="ACL8JK_000404"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGS1785347.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVESVESPAADLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVIIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDN
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VRVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(49246..49755)
                     /locus_tag="ACL8JK_000405"
     CDS             complement(49246..49755)
                     /locus_tag="ACL8JK_000405"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1785348.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTVSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(49755..50801)
                     /gene="pheS"
                     /locus_tag="ACL8JK_000406"
     CDS             complement(49755..50801)
                     /gene="pheS"
                     /locus_tag="ACL8JK_000406"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGS1785349.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            complement(51392..52807)
                     /locus_tag="ACL8JK_000407"
     CDS             complement(51392..52807)
                     /locus_tag="ACL8JK_000407"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGS1785350.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDITLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(52820..54658)
                     /locus_tag="ACL8JK_000408"
     CDS             complement(52820..54658)
                     /locus_tag="ACL8JK_000408"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGS1785351.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFVVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(54676..55515)
                     /gene="licT"
                     /locus_tag="ACL8JK_000409"
     CDS             complement(54676..55515)
                     /gene="licT"
                     /locus_tag="ACL8JK_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGS1785352.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(55815..57215)
                     /locus_tag="ACL8JK_000410"
     CDS             complement(55815..57215)
                     /locus_tag="ACL8JK_000410"
                     /inference="COORDINATES: protein motif:HMM:NF012492.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGS1785353.1"
                     /translation="MSERKTKTIILVHNKQLLDQWLDRLNCFLTFEEEEAIRYTASGR
                     EKVIGYVGQYGGTKKWLSKLVDVVMIQSLFKLENSQSLLDEYEMMIVDECHHVSALMF
                     EKVVAQFRGKYLYGLTATPERKNGHEPIVFQRIGEILHTADKRETDFKRQLQLRFTSF
                     AHLEIEKTKASNFIQLSDWIATDSARNQLILKDILAQVAEGRNILVLVNRIQQIDVFE
                     KLLKEKEVDGCYIISGKTKVRERTSLLEILEQLDKGFVLLSTGKYIGEGFDLPQLDTL
                     ILAAPFSWKNNLIQYAGRIHRNYKDKSLVRIFDYVDIHVPYLEKMFQKRQVAYRKMDY
                     RAIEGEEKQFVYVDSRYENVLRKDLAGERQECLLVLPYVHQTKLMNFLKEFRISQIEI
                     CIPETVANKAWLDQLKSKKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIVSELVAGLR"
     gene            complement(57227..58597)
                     /locus_tag="ACL8JK_000411"
                     /pseudo
     CDS             complement(57227..58597)
                     /locus_tag="ACL8JK_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397831.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
     gene            complement(58869..59672)
                     /locus_tag="ACL8JK_000412"
     CDS             complement(58869..59672)
                     /locus_tag="ACL8JK_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HGS1785354.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATVYHHTVDASTEEADLVSLRIVELLSRRGFRFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(59890..60031)
                     /locus_tag="ACL8JK_000413"
                     /pseudo
     CDS             complement(59890..60031)
                     /locus_tag="ACL8JK_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155197.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            complement(60052..61656)
                     /locus_tag="ACL8JK_000414"
     CDS             complement(60052..61656)
                     /locus_tag="ACL8JK_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS1785355.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNIKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFPRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWLDGDQNTNVSESNNLMNYLEN
                     GVVISDKIPESDNKNLDDIIKLITGCPIKFNVSGNKGQKNNIELIAKQRSFIDYWAKY
                     VSYLPFPTPEFFLANLCNSVDREGYDFSKDGNGKEYFRKKTQVALGIENITSEDIFQE
                     QRRAVSKIQPESSMFQCIKEKLEALF"
     gene            complement(61865..62956)
                     /locus_tag="ACL8JK_000415"
     CDS             complement(61865..62956)
                     /locus_tag="ACL8JK_000415"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HGS1785356.1"
                     /translation="MGKIVAIDLFSGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDKDINVVSGDEVKEYLKIDTDDKLMLVACPPCQGFSTIGTNNENDERNQLV
                     FQFLRLINELNPDFLLMENVVGMTRTRNEKIFKKFLTSIDNNYSVIYDILNTADYGVP
                     QSRKRLVLHGIRKEILDNTNLTLNLPSKTHSNIPELDLLSWINADIIMDLPPIEGGEE
                     YIGEGIYNHVANKLSNLNIERITHIRNNGGSRTSLPKSLELNCHKNRLGHSDVYGILD
                     INKPSITITGGCMSYSKGRFGHPTQNRALSAREAARLQSFDDDYIFVGNRGQLAKQIG
                     NAVPVKLAQASGNYFMSVYREIANGQSDN"
     gene            complement(63037..65688)
                     /locus_tag="ACL8JK_000416"
     CDS             complement(63037..65688)
                     /locus_tag="ACL8JK_000416"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGS1785357.1"
                     /translation="MSKELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VNLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAQSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVVNAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(65681..66259)
                     /locus_tag="ACL8JK_000417"
     CDS             complement(65681..66259)
                     /locus_tag="ACL8JK_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS1785358.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAETLQLNSQHQPNELNH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(66259..66819)
                     /locus_tag="ACL8JK_000418"
     CDS             complement(66259..66819)
                     /locus_tag="ACL8JK_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGS1785359.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIHAYASLPEVAYPAGFL
                     PVKTLEDEIYYLVHILPNRNQKENFPAGYGIVVKGTDKVIGSVDFNHRHEDDVLEIDY
                     TLHPDYWGRGYVPEAARTLIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(66806..67383)
                     /locus_tag="ACL8JK_000419"
                     /pseudo
     CDS             complement(66806..67383)
                     /locus_tag="ACL8JK_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813803.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
     gene            complement(67666..68061)
                     /locus_tag="ACL8JK_000420"
     CDS             complement(67666..68061)
                     /locus_tag="ACL8JK_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGS1785360.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            complement(68157..68411)
                     /locus_tag="ACL8JK_000421"
     CDS             complement(68157..68411)
                     /locus_tag="ACL8JK_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HGS1785361.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(68421..69755)
                     /locus_tag="ACL8JK_000422"
     CDS             complement(68421..69755)
                     /locus_tag="ACL8JK_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HGS1785362.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQIFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(69755..69988)
                     /locus_tag="ACL8JK_000423"
     CDS             complement(69755..69988)
                     /locus_tag="ACL8JK_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HGS1785363.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
BASE COUNT        20225 a        15675 c        12717 g        21440 t
ORIGIN      
        1 taacttttaa cgcatgtcgt tcaaggtaat aatccaaaca cgaaaccagt ccacgttttt
       61 caaggactgg ttttgatata gcacgtttaa gtaccgactt ctgagctact aattgatagt
      121 agtcgcccca gccagatacc ttatccgcta tataggcctt attatcacgt tcctgttcgt
      181 agagccacga tttcgctatc ccttcctctg acgattctta tttccagcgt cagacttaaa
      241 acggtctatc cccagaccgt tttaatccgc tacctcacga tagtcagact tgggaatcgc
      301 tattgggttc accggtagta ggtgcccacc gaggacttac acctcagata tacgacatgc
      361 ccgtcgtaca tcaaaaaaag ttgagacata gcgtcttcaa cttttttaca ttactttaac
      421 tactgattaa agtgagttta cgtcaacttt gataccaaca ccttgagtag ttgtgatagt
      481 caagtttgtt acgtaagttc ctttagctgt agctggtttt gctttttgga ttgtttcgtt
      541 gaaagcttta aagttttcaa ccaatttttc agcttcaaat gatactttac cgatgattgc
      601 ttgaacatta cctgcacggt cagcacggta agtgatttta ccacctttag actcttcaac
      661 tgctttagca acatccattg ttacagtacc agttttaggg tttggcatca agttacgtgg
      721 tccaaggaca cgtccaagac gtccaacaag agccatcata tcaggtgtag cgataactac
      781 gtcgaagtcc aaccaaccgt cgttgatttt agcaacaagg tcatcttcac caacaaagtc
      841 tgcaccagca gcttttgctt cttcagcttt tgcaccacgt gcgaaaacaa gaacacgtga
      901 agttttacca gtaccgtttg gcaataccat tgctccacgg atttgttggt cagctttttt
      961 aacgtcgatg ttcaagttgt aagcaacttc tacagttgcg tcaaattttg caaagttagt
     1021 ttcttttgca agtgctacag cttcttctac gctgtatgct tttgtgctgt cgattttctc
     1081 aagagcagca cgaagttgtt tgcttttttt agccattttc tattctcctt gtaagtggtt
     1141 caatcgattt tcatctccca cgtcacttct cgaaatgatg aagtcttgcg ggttttcagt
     1201 ctactatttt tctcttccta cggccttaag ctcccttgct gtacccaagt acaaggctca
     1261 gtcacttgcc tagtatgaaa agcaactaat agactgctgt gagattttct actgtgttat
     1321 tgattagtca acaacagtga atcccataga acgagcagta ccttcgatca tacgcattgc
     1381 agactctacg tttgctgcgt tcaaatctgg catcttagtt tctgcaattt cttgtacttg
     1441 tgcacgagta actgtagcaa ctttagtttt attaggtgta cctgatcctt tttcaacacc
     1501 tgcagctttt ttcaaaagaa cagcagctgg tggtgttttc gtaacgaaag taaatgattt
     1561 atcttcgtaa actgagataa caactggaat gatcatacca gcttggtcag ctgtacgagc
     1621 gttgaactct tttgtgaatc ccatgatgtt gataccagct tgaccaagag caggtccaac
     1681 cggtggagct ggtgtagctt taccagcagg gatttgcaat tttacaagtt tttcgacttt
     1741 tttagccatt tttaaatcct cctttgtggt tttggcggta attagagatt tttacctccc
     1801 acaagtatgt ttttcacata cccatccatt atacactatt tatctggaat tgcaagagaa
     1861 aagtttattt tttgtactca atgaaaatca aagagcaaac taggaagcta gccgcaggct
     1921 gctcaaagta cagctttgag gttgcagata aaactgacga agtcagctca aaacactgtt
     1981 ttgaggttgt gaatagaacc gacgcagtca gtaggtaagg cgacgctgac gtggtttgaa
     2041 gagattttcg aagagtatta atcgacgtag tctccgcctt caaagccata gtattcttcc
     2101 aaactgagac cacttgcagc aatttcttta gcttcttttc ctacataacg caggtgccat
     2161 tcttcagcca tatagcctgt ttccttttcc ttgcctttga gataacggac aacaaagcca
     2221 taatcagctg catgatccaa gagccattgg gctgcttttt cttctgtcac caaatcacca
     2281 tcagtcccaa tcacatcaaa ggccaagcct gtctggtgtt cgctatagcc aggacgggca
     2341 gagtaacggt cagctgctgc ctttccatct tggttgacat aatcttgata gagcttggtc
     2401 tgagtttcat aacttctaaa accactgtaa tgatcactaa tagggaaacc tgcctcttgc
     2461 atcgctttga tgagtttgac caactcagcc ttggctgttg gattttcccc gggattatag
     2521 tctttcgaca aaggataatg tttattggct acgatgattt cgtcgtattt tccttggatg
     2581 ctgtagtaat cacctttatt gaccacttct gcttttttct gggcagcccc ttgagactta
     2641 ctgccgactg tcccatcagc tttggctgtc tgttctgtct tagctgtgcc atcttcattt
     2701 tttgcttttt cttgtgaaca agctgctaga ctcaaggcta gcaaggctgt caagacaagg
     2761 tatctttttt tcatttctac tcctttattt ctaatagttt atctacttct gacgataaac
     2821 attcgactaa tcttttaatc tcttccggtt ttacttggca agtttctgct gtcatttctt
     2881 caaagggaac ccaccaaact ggcccacagc ccttgagacc gtggccattc atatcacctc
     2941 ttcgtctagg gaaaaggtgc cagtggagat gggcatcgcc atttcctagc agttcgatat
     3001 tcattttctc agcagcaaat gccttggcaa ctgcctcttg gactagactc atttcttcga
     3061 gaaaacggag tcttgtttcc tttttcaaat ggtgcaattc ggtaacgtgt tccttagcta
     3121 gaaaaagact atatcctgca aaatactggt ggtctccaat cacaagatag cctgtttcca
     3181 actctttgac aaagtaggga ttttctccct tcttgatgag ctcaattctc tggcaaataa
     3241 ggcacatatc aatctactaa attgcttcta agataggcat cgaccattcg ttctgttgcg
     3301 accaccgagt caatatgagt gcgctcataa gaatgactag actcgatacc cgcaccaaga
     3361 agagcgtgtt taacttctgc acctgcagac atagccgctg aagcgtccga accataaaat
     3421 ggatagatat ccagcttgaa tggaatatct tggtttttag ccaaggtcac caaatgttga
     3481 cggaagtcat agtgataagg acctgaagca tccttgacac agatggacac tgtgtactca
     3541 tctgtttgct gatcatcccc catagctccc atatccacag ccagatattc gactacttga
     3601 gcaggaatat tagaattagc accatgcccc acttcttcaa agactgaaaa ggcaaaatgg
     3661 gttgttactg gcaactcaat cttctcttcc atataaatac gaagcaggtt aagcaaaatc
     3721 gctgcgctga ccttgtcatc caaatgacga gacttgataa aacctgtctc tgtcacgaca
     3781 gttcgtggat caaaactgat aaaatcaccg acctcaatcc ccaaggcacg agtttctttt
     3841 tcattggtta ctttggcgtc caaacgcact tccatattgt cctgggtacg ttctgcagtt
     3901 cctgcatcct tgtagacatg gcaagaagtt tggtggatga ggatggtgcc tgatactttt
     3961 tcacctgtgc tagccacatg aacggtacag ttttcacctt caatcatgtt ccaaggaaaa
     4021 ccaccgatac ggtccaattt aagacgacca tctggtttga cagcacgaac aatagcaccc
     4081 agcgtatcca catgagcagt cacatagcga tgttgctcat cattttgacc tttgatggtc
     4141 acattgacac cacccttagc tgtgcgaact ggctggtaac caaaaccttc tagagtcttg
     4201 actaaataat tcgaaatttc acgagtaaag cccgttggcg atgcgatggc tgtcagttct
     4261 ttgatatatt ctactgtttg attcatttct tcacctcttt cgctacctat tataacacat
     4321 ttatcatcgg ataaaaaaag aaaatcactc ctgtagactt ggctacaaaa gtgatttaag
     4381 tgattattcc atttcaaaaa catcgctttc ttgcttgttt ggtagaacca atgagagcaa
     4441 gattccaaca atggctggca ccaaccatgg gagagatgcc ttggcaaaag gaagaacgct
     4501 aacaagattt gcaagaaact caaccttaaa cgagcttcct agtacgcttg caatggcaat
     4561 aactgtaacc acagcaattg tcaactgcat acctggtttt gaaagggcaa caaatttgtt
     4621 gacaatgaca atcataacga tagcaatcgt gattgggtac aagataacca gtactggaat
     4681 tgagtacttg ataatcgcat caagacccaa attggcaata gcaaatccaa tcaaggtaaa
     4741 ggctgtcgca taaaccttgt agctgatttg tgggaagcgc tcattaaaga actcagctgt
     4801 tgacacaatc aaaccaacag tcgttgtgaa gcaggttacg gtaaccatag ctgcaaggaa
     4861 gagttgagct gttgagccaa agatttcttg agtggcttgt gacaagatgt aaacacctgg
     4921 tgttccaccc ttcatcgctt cagctggtac tgggaaatga tttccaagaa aacctaaacc
     4981 gatgtaaaga gcgctgaagg caagggcaac aacgatacca acaacccaaa tagttgaaat
     5041 gtattctttc ttacttgaaa atccaagttg tttcaaggtt tgaactgcga ttacgctaaa
     5101 ggccactgag gcaagggcgt ccaaggtatt ataaccttct aggaaacctg taccaaaggc
     5161 agaagcttga taagcagctg aagcagcttg aggacttgtt ccaccatatt tgatagctcc
     5221 cagaacgacc aagataacaa tcaaaattgc aaagactggc gttaaaatac gtccaatgcg
     5281 gtctaagatt tttgatggat taagcgaaat caaataggct gccgcaaaat acagaaccgt
     5341 aaatacaatc aagccaagtc ctttatttgc atccgacaaa agggggctaa tccctacttc
     5401 gtaagctgtt gtagcagtac gtggggtagc aaagaatgga ccgattgaca agtaaagaac
     5461 tgagaggtaa agagtcgcaa accaaggcgc tatcttcgtt gaaatctcgt agatatatcc
     5521 tttaggattt agcgttccaa taataagggt caagacggcg ataccaacgc ctgaaaagac
     5581 aaaacctgcg atggcaggaa gaaaatgttc tccagataga gcacctagag aaggcggaaa
     5641 aatcaagttc cccgcaccaa aaaatattcc aaacaggagc aaacctgtta gggtaccttt
     5701 tttagccata aaaatctcct tcatatttat aaaatactga cctagtatac cacgattagg
     5761 agtctgaaaa aagcatcacg aggcaaatat taaatgtttt caattttctt aaaaataaga
     5821 attatctaaa aataaaactc tcctacccag tccacaccaa gtaggagaaa tgcaaaattt
     5881 taaagttctt caaaggctaa catgccaccc tggacattga taacattata accttgttct
     5941 aataggaatt ggcaagcacg cgccgatctc attccagatt tgcaaataat ataatgcaag
     6001 cgatctttgt ccaattaatc ataactatca gccaattgac taagcggtag gttgtaggca
     6061 ccttctaaat gaagagctgc aaactcatcc acttctctca catccactaa agaaagctgg
     6121 tcgttttggt aaagctggta aaatgcgtca aaggctattt ctttcattct ttttcttcta
     6181 atactcttcg aaaatctctt caaaccacgt cagcgtcgcc ttaccgtgcg tatgttaccg
     6241 acttcgtcag ttttatctgc aacttcaaag ctgtactttg agcagcctac gactagcttc
     6301 ctagtttgct ctttgatttt cattgactat aaaatggttt taattctttt tttcaaatct
     6361 ggcactactt ctgcctcaaa ccaaggattt ttggccatcc agatttgatt tcgtggtgat
     6421 gggtgaacta gcggaaaata ggctggcaga tagtctttat agtgtttcac cctctccgtt
     6481 accttcccac tgattttctc ctgtaaatag taggcttggg catattgccc aatcaagagg
     6541 gttaactgaa tatcaggcaa ttcctgtaag agctgcggat gccatttttc tgcaaaacct
     6601 gtacgaggcg gaagatcacc cgacttgcca tgtcctggaa agtagaaatc cataggcaaa
     6661 acagcaaaat aacctgaatt gtaaaaggta tcttcatcca cacctagcca gtcccgcaag
     6721 cggtcaccac ttttatcttt ccagtaaagg cctgcttctt gagttttaag tcccggagcc
     6781 tgaccgatga tattgatgcg agcagttttt ggcgctgcaa agagaggctc aatgccacgc
     6841 tctgtatagc tggcattctg cgaatccgcc atgatagcct gtttgattct ttcgatttga
     6901 gacatctact ttccctccaa aaagaagtcc aagcataaga tctcagactt ctatcgtttt
     6961 atttgatcaa ttcgtaaata gcttcggcat aaattgctgc tgctcggaag agatcgtcca
     7021 aggcaataaa ttcattggct tggtgcatgg tatcaattga gtctgggaac atagcaccat
     7081 aggcaactcc gcgctctaac aagcgaccaa aggttccacc accgatgact tgttcatgac
     7141 cttgtaggcc tgtttgtttt tcatagacat tcaacaaggt ttgcacaagt ggatcttcca
     7201 ttggcacata gtgaggggta tgaccatgtt ctgatagact gacagaagca actggcaagt
     7261 tttctaggat tgatttgatt tgttctggac ttgttccttt tggatagcgg atgttaaggg
     7321 caatggtatt atcagcactt gtttcatcga agcggaagac tccggcattc atagaaagag
     7381 cacccatctt ttcatccaca tgagcaatct tgagattttc accctcatga tcgttcaaga
     7441 gaattttacc tgcgatgtca aggtagtctt tggctggacc agcaaagcca aactggctga
     7501 ggaagagggc aaggtaagtt gcgccattga cacctgaagc aggcatagca ccgtgggctg
     7561 atttaccaat gatcgtcacc ttgtatttgc cagcttcttc ttggagttct cctctaagtt
     7621 tgtgttctgc aacaaaggca tctagtttag cttgcaagtc agccaaatca cctgaaacga
     7681 ctgctgttgc tgattctggt accatatttt cacgtaaacc acctgtaaag ctgtgaagac
     7741 gggcagcacc tgtattttct cctgcaaagt ggaggtattc cgtgatattt cctttttcac
     7801 cattgatgat tggaaattca gcatctggtg agaaaccgaa atctggtttg gcaagtccta
     7861 cgtgctcaaa gtagtagtcc atgtctgccc agcctgattc ttcgtctgtt ccaacgatga
     7921 agcgaacttt cttagaagtt ggaagaccca attctttgat gattttcaaa ccatagtaac
     7981 aagctgttgt aggaccctta tcgtccgaag ccccgcgcgc ataaaggcga ccatctttga
     8041 tagttggtgt gtaagggtct gtgtcccaac cgctaccagc aggcaccaca tccatatggg
     8101 caaagattcc gagaacttct tctccatcac caaactcaaa atgtcctgca tagttatcaa
     8161 cattcttagt tgggtagcca tcgcggtctg cgatttcaag gaatttctcc aaggctttta
     8221 ctggaccagg cccaaatgga tgctgggcat cagccttgct gtcatcacgt tctgaattga
     8281 tttccaaaag gctaaacaag tcagccaaga ggtcttcttt gcgtttttct acttctgctg
     8341 taaaatcaat tgctgtcatt ttttcttctt tctatctttt ctcgatgatt tcatccactg
     8401 gcaagcggta gcttggttcc aatttttcgt ctgtataacc cactgtgatc aagagttctg
     8461 ggcggaaacg gtcttcgatt tccaaaactt cattaacttt tgatttgtca aaaccaagaa
     8521 taatgttaga accaattcct tggtctgtca atgcaagaac caagttcatg gcaaccaaac
     8581 ctgcattgag agctaggtag tcgctgactt gttgctcact gtaacgggca aactcagctg
     8641 gcagattttt cataaaatat tgaagttgct cttcagaaaa gttattagca ccaccaacac
     8701 gggcaatctt acgagcacgt ttggctaagt ccgtatctgt aaacaaggca atggttacag
     8761 gcgctgatga tacctgttca aaattggaac cataagctaa ctttgccagt tcagcatttt
     8821 tctcacgtac caccacaaat ttccaaggct ggctgttgtg ggcgcttggc gccaaggttg
     8881 caatttcgat agccgtacgc acatctttgg gatcaacaag cttatcagta aaatgcttag
     8941 tcgcatgacg ttttttattt aattcaagaa atttcataat cgatttcctt ttctaattct
     9001 actgcttcca ttctaccata atttgaaaga gcttgcaggg atttttcatg attaagtttt
     9061 tctatcacag acataaaaga tatatattgg tttatcagga aagtttctga taaactagca
     9121 agtactttac atttgaatgg agacagtatg aaaaaattta gcctattact agctatccta
     9181 ccatttttgg ttgcctgtga gaatcaagct acacccaaag agactagcgc tcaaaagaca
     9241 atcgtccttg ctacagctgg cgacgtgcca ccatttgact acgaagacaa gggcaatctg
     9301 acaggctttg atatcgaagt tttaaaggca gtagatgaaa aactcagcga ctacgagatt
     9361 caattccaaa gaaccgcctg ggagagcatc ttcccaggac ttgattctgg tcactatcag
     9421 gctgcggcca ataacttgag ttacacaaaa gagcgtgctg aaaaatacct ttactcgctt
     9481 ccgatttcca acaatcccct cgtccttgtc agcaacaaga aaaatccttt gacttctctt
     9541 gaccagatcg ctggtaaaac aacacaagag gataccggaa cttctaacgc tcaattcatc
     9601 aataactgga atcagaaaca cactgataat cccgctacaa ttaatttttc tggtgaggat
     9661 attggtaaac gaatcctaga ccttgctaac ggagagtttg atttcctagt ttttgacaag
     9721 gtatccgttc aaaagattat caaggaccgt ggtttagacc tctcagtcgt tgatttacct
     9781 tctgcagata gccccagcaa ttatatcatt ttctcaagcg accaaaaaga gtttaaagag
     9841 caatttgata aagcgctcaa agaactctat caagacggaa cccttgaaaa actcagcaat
     9901 acctatctag gtggttctta cctcccagat caattacaat aacactcttc gaaaatctct
     9961 tcaaaccacg tcagctttat ctgcaacctc aaagctgtgc tttgagcaac ctacggctag
    10021 cttcctagtt tgctctttga ttttcattga gtataagata tactaaaagc gattggacca
    10081 gccaatcgct tttttagttt gcattggcta ttttaggaaa ctcttacaaa aaatcaaaaa
    10141 aattcttcac atcctctaca tacccatgct tttctattaa gctggctaaa agttccagat
    10201 tgtgcccctg atagttatcg tcacgacgca gttcttcata catttcaata aagggaagcc
    10261 ccttggactt ggccaattct aactcagcct cgtaatcata agcaacttta cgaaattgga
    10321 tattgaccaa ttccccatct tcaacttcta tcacggcata ctgggcacgg tgatttttta
    10381 acgcctccca attaaaatag ggcatgccaa tcgaccctgg attgatgatt tgttgccctt
    10441 gacttccata acgaagcaac tgcttgtgaa catgaccata aactgccacg tccgtttccg
    10501 catctagcag ttggtcaaat ttctctgtat cattctcaac tagcaagtca ccaccatagt
    10561 tcttatttgg caaattatga gagatagaaa agcgcagtcc agcaatttct ttcttttcca
    10621 gcaaaggcaa gcttcgtagc cagacagtcg ttgcaggatc cattcgctcc atcaaaaact
    10681 gggtcatacg caagagctga acttcctgtg ggtcttctaa gccatattgc ccatctaaag
    10741 cctcaaggac acgatcatcc caattgcctc gaacacttgc tgtgatagga aggtccttta
    10801 gcagggcgac taagtcattt gcgcctggac caggaagaaa aatatctccc agaagccaat
    10861 attcactggc cccttgattt ttagcatctg caatcactgc ttctagcgcc gtcgcattgc
    10921 catgaacatc tgataaaatt gcgattttat ggttcattgt ggtttccttc cgtttggtaa
    10981 tctactcttt cttctgctac ttgaggcaag gcttctccct gcgggttcaa ctttctttgc
    11041 acagcctctg caacgactct aggtacccca acttcgacaa tctcatccac actggcttcc
    11101 ttgattttgg tcaaagactt gaaatgcttc ataagattct gcttgcgttt aggtcccaga
    11161 ccgtcaatcc catccaattg agatgagaaa gaatttttgg agcgcagttg gcggtggaag
    11221 gtaatggcaa agcggtgcac ctcatcttgg atgcgttgga ggaggaaaaa ttcctgagaa
    11281 ttgcgagaca agtccaccac ctcaagcgga tctccaaaga gcaattcatg ggtttggtgc
    11341 ttatcattct tttgcagccc agcaattgga atatccaagc ccagttcctc ttggataacc
    11401 tgcttagcga tattgacttg accttgcccc ccatcaatca caatcaaatc tggaggagtc
    11461 aaagcctcac gctgtactcg accatagcgt ctgcgaatga cctctctcat gctggcatag
    11521 tcgtctggtc caacaaccgt ttttatcttg tacttacggt aatccttctt actcggttta
    11581 ccgttgacaa agaccaccat agccgaaaca gggctagttc ccatgatatt agagttatcg
    11641 aaggactcga tacgtactgg ggtcgggatt tggagcaaac gtcctagatt ttcaatagct
    11701 ccttgggtct tctcgacaga tttctctagc aggttaaatt tctgctccag actaacacgt
    11761 gcatttttta tggctagatt gaccagctgt tttttctctc cacgttgggg tttgagaatc
    11821 ttggtatcca ccaaagcctt gacagcctct tcgtcaatat cctgcggaat cagtacctca
    11881 ttgagaacta ggtgagattt ttcttgatag aattgtccta cataggtcaa aaaatcctca
    11941 tctggatcat tgaagtaggg gaagagattg acatcgcgct cgatgagctt accctgacgg
    12001 acaaagaaaa cctgcacaca catccagccc ttatccacat agtagccaaa gacatcgcga
    12061 ttttggagat ccttagccat gacccgttgc ttggttcgaa gcgttccaat agcctgaatc
    12121 aggtcacggt attccgccgc acgttcaaac tccatagtct gggctgccgc tgccattttg
    12181 ccctttagct catcaatgat tttgttatcc tgccctttca gaaaatcaga aacctcctgg
    12241 gccatagact tgaaataagt ctcatccttc ttacagatgg tgtgggccat gcattgaccg
    12301 atatggtaat aaaaacagac cttagagggc gggttggtac acttacgaaa agggaatatc
    12361 cgatccagca accgcttgat ttcattggct gcccccacat cgggataggg tccaaaataa
    12421 agacctccgt cctttttgac ctgacgagtg ataatcaagc gtggatagcg ctcattggtg
    12481 attttgatga aaggatagga cttgtcatcc ttgagcatga tattgtactt gggcttgttt
    12541 tccttgatca ggttgatttc taggagaagt gcctcaatat tagactccgt aacaataaat
    12601 tcaaaatcca caatttcaga caccagagcc tctgtcttgg tatcatgact tccacgaaaa
    12661 taggaccgta ctcgattacg cagattttta gcctttccta catagataat ggtgccattt
    12721 ttatccttat gaatgtagca accagggctg gtcggcaaga gctctagttt tgatttaatc
    12781 aagttgttca tagttccatt atagcaaaaa aagtagggaa agatagtacc ctactcacta
    12841 gtctcatata tttttcggag gtttgcaaca tcctcttcct ggataccata aaaggaacct
    12901 gctggttgca tgacagactt ctcatctgta tggtccaagc caatcgcatg acctaactca
    12961 tgttctgccg tatggacaag gcgttcatag gagtagccat agtatggatt ggacaaataa
    13021 taatgattca accgcaccgt tacggacaag aattgccctg ttaagagatt agtttgactt
    13081 tccgcctctc ctgccacagg agtgcctccg tcgttcatct ccgtagccgt aatatccgcc
    13141 ttactagact cagtcacgag ttcaaagtta aaagcacccg tttgattcca gttctggatt
    13201 gcttctaaat aagcctcttg aaagcgtgaa tccatctgcg gatccaggta aatacgagca
    13261 gaggcctgtg cccaccttcc ttcagaatgc tggtgactat ctgtctggct taacttaggc
    13321 agttgccctg ttttctccca ttggtcaata ctttgttgac caatttttac tgaccgttct
    13381 gcttgcttta gcgctccttg aaaatccccg ttcagatacc agagaagtcc gaaagcaagc
    13441 acacataaga gcacaactat ccaaaccaga cgccaaaaca aacgccacac aaaagaaaag
    13501 aaagccccta tcaaacgaaa aagccagcgc atgtctctcc acctttctag caaataagaa
    13561 ttattttact aaaagaagct aaaagaaatc taaatactga ctttttcatc ttaacgtcct
    13621 actatttttt tgagtaactg gatagctttg tattttaaag gcgatggatg gtaacggaaa
    13681 gtacccgctt tgcgtacaat atagccatta aaattctgtt taaaacgcaa aacaccatca
    13741 cttccatcaa aaatcccttg aatgcctagg aagttgtatt taggtattcc acgttttatg
    13801 ctttccaaca taacatattt ttgaagcagt gcaggggcat agaacttatt aaactcagtg
    13861 taggaaccac taaagagata agtcgtttcc tgaggcatat aaacaaataa actaccagct
    13921 aaaacaatat cttcttctcc atatttttca atcaagtctc gcgcttctgc ttttcgaact
    13981 tcaaacgttt caaattgact agaatattct ctcagttgat tttgtttttt ctcagaatga
    14041 ggatttttac tcaaatcaag tcgcaacttg tccaattttt cttctagttt actttgttca
    14101 ccttgcaatt tgctcatata ctccgaaaaa ttcaagcttg ctatgagaaa ctccgcttgt
    14161 tctccaaaag tatcataaaa atgctcataa tattctaaac ttttatcact atattctcta
    14221 cgttcagagg tttcttttgt tatattctta aaaatcgata gttcttcacg ttttaacttt
    14281 ttcaaccgaa tgccaaaggt ttcagccttt ttcaccaagg gtttaccctt tttgctaaaa
    14341 cttttaagca aactcttttc agttaattca gttaaatctt tatagtataa ccaatctggt
    14401 tctccacctg ggtaacctgt tgttaagcca tcaaattgat aacctaaatc agtcaaatct
    14461 tgaataatac tttttttctc agcatctatt ggattacctt ggctatcaaa agtttgataa
    14521 gtttcatagg gttttacaag caactctaat acaccatttt gcttggcata ttcttttaac
    14581 tctgcataaa aaactggaag agcatcttgt tgggtataaa tcggccccga attgagttcc
    14641 atatgcagac cacccagcat gggcaggcta taaaccagag ctgcaacttg aatttctcct
    14701 tcttgtttca aagcaagata aacaattcga gcccctcttt tttctagcaa atcccccatc
    14761 tggacagatt gcataaagga acgagaagaa acctgatcag aataagtctg aaactcttct
    14821 ttcgtgagtg ttgttagtgc catatactta ctttctatgt ttttttctta atgttttacg
    14881 gaaatcaaga gcaagtctta acagaggata gagaggatga gtgggcattg taaattcacc
    14941 caagtattct tcaatcgttg gattaaattt ttccttaaaa tgataaagtc caccattgag
    15001 agagttttca acaccaccta aattttgcca gatcatacct cgttcaaagg catagcgagc
    15061 cgtttcatac caagttaaaa ttggtgcatt gtaacgttta aaatcatcat ccataccagc
    15121 atatatattg acagaggtag taccaaattc caaactcaaa gtagccgcta aaggaactct
    15181 cgcttgacct acatctatat attcctgcaa gaaggtcaat tcctctaaca aacgttcttt
    15241 ttccttcttc tgcgcttcta cttttgaagt tcgagtcgac tcagtaaagg tctcttccaa
    15301 ggctctattt ttcgctaact gttcttctaa ctcttgcgaa cgtttagaaa catccaaggt
    15361 ggccaaggtg atataggcct tgtccttaaa attatctaac aattttttat aataggcttc
    15421 attcctcaaa tgaatctctt ttcgcttctc agtttttttc atcaactccg aaaatgaatc
    15481 taatagttcc agtccaccat attgaatctc aagccctttg tttcgtgctg ttcgaatagc
    15541 ctgttttgtt gacttggaaa gtttatcttc ttcaaaattt tccttgtata ttttcgcctg
    15601 aatacgaggt tgaatggtgt ctcccatttc ctccgttttt cctgaccacc ttactcccat
    15661 ttgttgcaaa ctatcaataa tagccagatt ttcaggaaat tctgtctttt cctgattgat
    15721 taaactttga gataggcaaa tacttgggtc aaaagtcaca aaaaccgctc tcttactgcg
    15781 agcataggac ttaatagact gaatggcaaa attcaagagt tctttatccc cataatccaa
    15841 tataggtcct cttgggatgt aaaacatttt atagcctagc ggaagagttc taatcaaaat
    15901 actagctgtc gccagtaatt tttcttccct gtaaacacca aacttctcat gttgccaatt
    15961 agacttaact tcctcccaag cactactttg taatacattg gctaattcat gttctttgac
    16021 aaactgatca tattctaatg tgggaatgcc aatttgataa cggtacattt cctactctct
    16081 ttcctccagt attttattac tattctacta ctttcgtttg aaaagtctag tgaaaacata
    16141 ttttatttta gttctactcc ccctatgctg aagttcaaac taagtcagtc tctcttctaa
    16201 tttgaaatca attggtaggg ttgttaaaaa aacttccaat tgtttttccc agtagtacca
    16261 ctcgtgagtt ccagcgctat ggctataggt cacatcaaaa cctagttttt tgagattttt
    16321 cactgcgaga ttattggctt cgtacaagaa atcctgttcg ccacaccacg cccaaagttt
    16381 ggtcttttta tccgattttt tagccagact ttcaagagaa tagggactag ttgtccagtc
    16441 tctaatctct ccaaaaacac ctctccagta ggctggactt cccagatttt gactttcagg
    16501 agaaaagttt tgaaagctga gggcacctga aaaactagct gcatgagaaa aacgatttgt
    16561 cgtaagagcc agtttgaagc agccgtagcc tcccatagaa agaccagcga taaaggtctt
    16621 ttcacgcttg ctcgtcatat tagggaagaa gcgtttcaga acctgtggca attcctctgc
    16681 tagagccgtg tagtagtcaa aaccatactg ggtatcggtg taccaaccat tgctggtatt
    16741 gggcataaca acgatgagat tagttcctcg aagcaagcgt tctacattgg tccgcttaag
    16801 ccaactatta tgatttccag acatcccgtg caaaaggtac aagacgggaa tatcttcaca
    16861 ctctggttct tccactcgat tggcatcagg gtagaggaca ttcacccccc actccatatc
    16921 caatacttgt gagtaatact cgattttcat tactgccatg attttctcct tctatttttc
    16981 tataagaaaa agccgaaact cgactttctc tctgtttatt tcaacgatta ttttgcttcc
    17041 atgactactg gtaaaatggc tgggcgacgc ttggtttgat caaagaggta cttggtcaga
    17101 ttgtcacgaa ccttaccttt gagatctgcc cagtcaaagt catctccttg aagatactct
    17161 tctaccgttt ggttaatcaa ttctgaactt tcacggagaa tatcgcgact cttcttgaga
    17221 taaacaaatc cacgcgtgtg aacacgagcc ctagccacaa ttttcttctc acgacggttg
    17281 actgtaatag ccacgatgaa aattccatcc tctgacaaga ccttacggtc acgaagaaca
    17341 acatttccaa catcaccaat ggcattccca tcaatcaaga tatctcctgc tgaaaccgat
    17401 ccagctggaa caaagtctcc attctcgtaa gccatggtcg tccccttttt aggaatgaag
    17461 atgcgttctg gcaacatccc aactgccatg gcagccttag cgtgagcatc caactcacga
    17521 tactcccctt ggacagggaa gaggtactta ggttgcaaaa gattgatcat cagctgcaaa
    17581 tcacgcacat ttccgtgccc tgatacatgt aaactttggg taatcaattt gacaacccca
    17641 cctgcctgat aaatcatatt ttccacacgc gcaacaaagg cttctttagc aatagacgga
    17701 gccgtagcaa tatagactag gtccccatcc ttgatttcta cataacgatg gcgaccaatc
    17761 gacatcttac gaagtccatt gataggctca cccatacgac ctgtctcaag aataatcaac
    17821 tcatggtctt caaagcgaga catatcttta ggcttaatca aaagaatttc gttggctaaa
    17881 gacaacttct taagacgaat cgctgtgcgg acgatatttt caatatcaaa tcctgtcaag
    17941 acgatacgtc gacctgtttt atccgcagcg tcaaaaatct gctgaatacg agaaagatta
    18001 ctggaaacag ctgcaacgat gatacgacct tcccagtcag caatagtttg ggtaatttca
    18061 tccctaactt cactttcact agccacctga atattgctgt ctgcattggc cgaatcactg
    18121 aggagagcca ggacgccgtc acgaccaatc tctgccaaac gagcaaaatc agttgcataa
    18181 gattcactag ccgtttggtc aaatttgaag tcacctgtat aaacgatgct tccttccgat
    18241 gtcttcaaga caattcccag actctctgga acggagtaag tcgtagggaa gaaggaaacc
    18301 actgtcccac caaaatcaat ctccgtattc tcatcaatga catggaaatc attaaatttc
    18361 ttaacggcat catttccttt gacaaagagc tttgccaact caatggtcaa ctcagaccca
    18421 aatacaggaa ctttagcctc tgccaagaga tacggtagag caccaatggc atccgcatgc
    18481 ccgtgggtca agaaaacccc agcaatacgg tcgctatttt caaaaaggta atccatgttt
    18541 ggaatcacca catcgacccc taattgttca ttttcaggat attttaaccc tacattcaaa
    18601 acaaaaatgg actctccaat ttcagcaatg tacatatttt ttccattctc acgcacacca
    18661 ccaagtgttg ttaaactgat attactcatt tttcctccaa aatcttagtt tatcttgatt
    18721 atagggcaat tctaccctct tattctaaaa gttctgatac tttcagccga atcttttcct
    18781 accattatac catttttttg atgattttca aaatgaaggt ctgttttcaa aaaagagttg
    18841 atttcccaac tctttcctaa cttctactct ttttccatca aaaaatcata aatttcttgc
    18901 accgtaccca gcgccatcat ttcttggtct ttaacggttt gtttgagatt ttggtaaatt
    18961 tgactttctc ctatctcccg ctttggcgcc tctttattga ctgtcatcac accatctttt
    19021 atcgtcacaa agcctagttc ttcaaatact tgaatcatct tgaccagcaa gatttgttga
    19081 atattaagat atgcagccaa atctttcagc ttgtagcgaa tatcaaactc tgggaactgg
    19141 taaatagtct tgtacaattt ggcaaactga tctctagtcc cataacctgt cagataataa
    19201 gccttgtcaa tatcattttt gaaatagaca gcagagaaat gctgttcctg aaaaatggtc
    19261 ttcagctgag taatatcctc tggaatgttt tttacgacaa cagcttcact agccgcaaga
    19321 tttggcagtt ctccaggaaa atccaagact ggaacacctt ctggcaagac tgcatttttt
    19381 ccacgaatgt taaaaagttg aacaccttcc actcgcgcat ccaccatcat caactggagg
    19441 gcagtttggc cattccattg gttgacagac aatttaaccg ctaactctag attcttggtt
    19501 tgagaaaact ctgtcgccca tctgccttga ccaaaggcta ccacttcaaa actcgcctca
    19561 cccttggaaa ttttcagctt tagatgggca ttacctgccc ccatagtacg agcactttcg
    19621 acctgaaaat tcttgatata aaaaataggt ttctgattat ccattccaaa aggagctaaa
    19681 cgttcaaaac ttttgaccgt ttccaagcta agtgcctcca aatccaactc ttcatctagg
    19741 tttaacttat tcttgccacc agcatctgca cctttttcac gaacataatc ttccaaaacc
    19801 tgagataaat ctgagagttg ctcaacttcc agcgtcatac ccgctgcacc tgcatgacct
    19861 ccaaaggcga tgaagaggtc tcgatgggga tccagagctt caaaaatatc gaccgcttcc
    19921 acactacgag cactgccctt ggcacgaccg tcttctatat taagaacaat gactgtctgt
    19981 cccaattctt ccaataaacg accagccacg attcctagaa ccccaggatt ccagccttcc
    20041 ttggccaaga cctgaacctt cttctcagga tccaccatgg tcttggcttc ttcatagata
    20101 gactgaacga tttccttgcg ctcttcgttt ttctggtgaa tcataagggc aatctcatgc
    20161 gcttcctcat catcaaatcc agtcaacaaa tcaatggcag gattgggatc atccaagcga
    20221 cccaaggcat tcaaacgagg agcaatctgg aaaccaaccg tttcttctgt tacttcgttg
    20281 gcagcaatcc cagccatgtc cagcatttct tgcagaccaa tgcgctgggt atgacccaac
    20341 atttccagac catattgaac taagatacga ttttcatccg tcagactcac catatctgca
    20401 atagttccaa tagcgaccaa atcaagcaat tccacttgca cttcttctaa cagggcacaa
    20461 gccaacttga aagcaactcc acaaccagcc aaatatttaa aaggataatc cgcatctgga
    20521 tgttcaggat ggacaatagc ataagcatct ggcagggttt caggcatgga atgatggtct
    20581 gtcacaatga catctactcc catagactga gccaatgcaa tagcctcatg accagcaacc
    20641 ccattgtcca ccgtcacaat caaggaaatc ccttcttgct cgataaagta tttataaaca
    20701 ctagcattag ggccatagcc atcggtaaaa cgatttggca ggtaaactcg gcactcagca
    20761 ccaagttgtt ccaaactttc cttcacaata gaagccgaag tcatgccatc cgcatcatag
    20821 tctccataaa caagaatatt ttccccttct tcaatagcct gacgaatccg ctccactgcc
    20881 ttgtccatat catggagcag ataagcatca tgtaagtcct ccaaggaagg ttctaaaaac
    20941 ttcttcagac tttcttggtt ctgaatccct ctctcaaaca ataaccgagc cacctcagga
    21001 cccagtccag ccttcttggc tatctttgta aaatccgcat cttctacctg cagggcaaac
    21061 tgccattcat aagtaggtgt tatcaaaaag acatccactc tttctaagaa ttctattgct
    21121 tcattataac atgatttaga cgttttctct atccagattg cttttttata acattttata
    21181 gtatattgaa actagaatag tacacctcta cttctaaaat attgttagaa atcgatttga
    21241 ctgtcccgat cgatttttcc tgttcttatt tcactatagt gaattttttc agatatgatt
    21301 tgacaagaac attcttttat tgtagaaccg tgttataaaa tataacacaa tagagatctc
    21361 tcatggcttt agtagaattt aaaaacgtcg aaaaatatta cggagactac cacgcattcc
    21421 gcaacatcaa tctccgtttt gaaaaaggac aagttgttgt cctgcttgga ccttctggct
    21481 ctgggaagtc cactcttatc cgtacgatca atggtttaga gactgttgac aaaggaagtc
    21541 tcctagtcaa tgggcaccaa gttgctggtg ccagccagaa agatttggta cctcttcgca
    21601 aggaagtcgg catggttttt caacatttta acctttatcc acacaaagct gtgttagaaa
    21661 acgtaacgct tgcacccatt gaagttctag gaattgataa aaaagaagct gaaaaaaccg
    21721 cccaaaaata tctggaattt gtaaatatgt gggacaagaa agattcctat cccgccatgc
    21781 tatctggtgg acaaaaacag cggatcgcca tcgctcgtgg tcttgctatg catccggaac
    21841 tcctcctctt tgatgaacca acatctgctc ttgatcctga gactatcgga gatgttctag
    21901 cagttatgca gaaactggcg catgatggga tgaacatgat catcgttacc cacgaaatgg
    21961 gctttgctcg agaggttgcg gaccgcatta tctttatggc cgacggagaa gttttagtag
    22021 atacgacaga tgtcgataac ttttttgaca atccaagcga acctcgtgcc caacaattcc
    22081 tcagcaaaat tatcaaccac gaaagtgaca aagtcaaata aggaggcgcc tatgaaaaaa
    22141 aattcttttt atcagcatta ttgattagcc ttttcggcct tgctgctgcc aaaccagtcc
    22201 aggctgatac aagtatcgca gacattcaaa aaagaggcga actggttgtc ggtgtcaaac
    22261 aagacgttcc caattttggt tacaaagatc ccaagaccgg tacttattct ggtatcgaaa
    22321 ccgacttggc caagatggta gctgatgaac tcaaggtcaa gattcgctat gtgccggtta
    22381 cagcacaaac ccgcggcccc cttctagaca atgaacaggt cgatatggat atcgcgacct
    22441 ttaccatcac ggacgaacgc aaaaaactct acaactttac cagtccctac tacacagacg
    22501 cttctggatt tttggtcaat aaatctgcca aaatcaaaaa gattgaggac ctaaacggca
    22561 aaaccatcgg agtcgcccaa ggttctatca cccaacgcct gattactgaa ctgggtaaaa
    22621 agaaaggtct gaagtttaaa ttcgtcgaac ttggttccta cccagaattg attacttccc
    22681 tgcacgctca tcgtatcgat accttttccg ttgaccgctc tattctatct ggctacacta
    22741 gtaaacggac agcactacta gatgatagtt tcaagccatc tgactacggt attgttacca
    22801 agaaatcaaa tacagagctc aacgactatc ttgataactt ggttactaaa tggagcaagg
    22861 atggtagttt gcagaaactt tatgaccgtt acaagctcaa accatctagc catactgcag
    22921 attaaggagg acaccccatg acagatttat catcttggac agcctatttt caggattttg
    22981 gacaattttt caatggtttc ctcttcaccc ttgccctagc ggttggttcc tttatcctcg
    23041 ctatggtttt gggcatcttc tttggtgcca tgtcaaccag taaacgtcca attttacgca
    23101 ttttagctcg catctttgtt gaattttacc aaaatactcc cctcttggtg cagtttgtta
    23161 ttgtttttta tggcctacct cttatcagtg accatatcat catgattcca atttattgga
    23221 cagccgttct ctgcgtggga ctctatcacg gcgcttatat cgctgaggtt attcgttcag
    23281 ggattcagtc tattcctagt ggtcagatgg aggccgcctt gtcgcaaggt tttacctata
    23341 tcagtgccat gcgcttgatt atcttgcctc aggccttccg catcattctc cctccattga
    23401 ccaaccaaat tgttaacctc atcaagaaca cctctactgt agctatcatc tctggagtag
    23461 acttgatgtt tgtgactaag tcttggtcgg ctctcaacgg aaactatata ccagcctttt
    23521 taggtgctgc tcttctctac tttgctctat gcttccctgt tgcccagttt ggtcgcaaga
    23581 tggagcaagc caacaaaaaa gcctattcac tttaggaggt tactatggaa tctattttag
    23641 aagttttaac cccagataac ctagtcttta tctttaaagg atttggcttg accctctata
    23701 tttctctgat tgccatcatc ctctctacta tcatcggtac ggtgctagct gtcacgagaa
    23761 atggcaaaaa tcctgtctta cgcattattt ccagtattta tatcgagttt gtgcgcaacg
    23821 ttcccaacct tctctggatt tttactatct ttttggtgtt caaaatgaaa tccacaccag
    23881 caggtattac agcctttact ctctttacat cagcagcctt ggctgagatt attcgaggcg
    23941 gtctcaatgc cgtagacaag ggacagtacg aagcaggaat gtcacaaggc ttcacctcag
    24001 cccaaatcct ctactacatc attctcccac aagccatccg caaaatgcta ccagccatca
    24061 tttctcagtt tgttaccgtg attaaggata ccagtctcct ctactctgtt atcgccctac
    24121 aagaactctt tggagccagc caaattctca tgggccgtta tttcgaacca gagcaggtct
    24181 tcagtcttta catcctgatt gccctcatct acttcagctt taacctagca atttctagcc
    24241 tgtctcatat gctagccaaa cgttggcaac aagctgcaga ataacactct tcgaaaatct
    24301 cttcaaacca cgtcagctct atctgcaacc tcaaaacagt gttttgagca acttgcggct
    24361 agcttcctag tttgctcttt gattttcatt gagtataaac agccactctc cagttcaatt
    24421 ggagagtttt ttgatgagag tagatattta tagacctcaa tttgacacca tacattttct
    24481 atgataaaat gtaacaaatt tatttacaac aaatcgaaat ctaaatgaaa tggaattttc
    24541 tatgaaatca gtcaaaggac tactctttat catagctagt tttatcttga ctcttttgac
    24601 ttggatgaac acttctcccc aattcatgat tccaggacta gctttaacaa gcctatctct
    24661 gacttttatc ctagccactc gtctcccact actagaaagc tggtttcaca gtttggagaa
    24721 ggtctacacc gtccacaaat tcacagcctt tctctcaatc atcctactaa tctttcataa
    24781 ctttagtatg ggcggtttgt ggggctctcg cttagctgct cagtttggca atcttgccat
    24841 ctatatcttt gccagcatca tccttgtcgc ctatttaggc aaatacatcc aatacgaagc
    24901 ttggcgatgg attcaccgcc tggtttacct agcctatatt ttaggactct ttcacatcta
    24961 catgataatg ggcaatcgtc tccttacatt taatcttcta agttttcttg ttggtagcta
    25021 tgccctttta ggcttactag ctggttttta tatcattttt ctatatcaaa agatttcctt
    25081 cccctatcta gggaaaatta cccatctcaa acgcttaaat cacgatacta gagaaattca
    25141 aatccatctt agcagacctt tcaactatca atcaggacaa tttgcctttc taaagatttt
    25201 ccaagaaggc tttgaaagtg ctccgcatcc cttttctatc tcaggaggtc atggtcaaac
    25261 tctttacttt actgttaaaa cttcaggcga ccataccaag aatatctatg ataatcttca
    25321 agccggcagc aaagtaaccc tagacagagc ttacggacac atgatcatag aagaaggacg
    25381 agaaaatcag gtttggattg ctggaggtat tgggatcacc cccttcatct cttacatccg
    25441 tgaacatcct attttagata aacaggttca cttctactat agcttccgtg gagatgaaaa
    25501 tgcagtctac ctagatttac tccgtaacta tgctcagaaa aatcctaatt ttgaactcca
    25561 tctaatcgac agtacgaaag acggctatct taattttgaa caaaaagaag tgcccgaaca
    25621 tgcaaccgtc tatatgtgtg gtcctatttc tatgatgaag gcacttgcca aacagattaa
    25681 gaaacaaaat ccaaaaacag agcttattta cgaaggattc aagttcaaat aagtaatcat
    25741 actctcctgg gatttcccag gagagttttt tatagccaaa tgaaataaga caggaacgat
    25801 ggaattttgg cattcaaatc aattgataag actattttat agtggagtga aataggatac
    25861 gaacaaattg attaggaaaa tcaaatgaat ttatagaaat cttttagcag ttatgttatc
    25921 ctattctagt ttcaaaacgc tatagaagca gcattgtgct agtctagatt cagtttacta
    25981 tactaaaacg agtagcttga aatcaaaaaa cccaccctca caggcaggtt ttatctgtat
    26041 tattcagcta gattatgctt taccttctga accgaatacg tcgatacgtt cttcaaccga
    26101 tgcttggata gcttttacac cgtcagcaaa gaatttacgt gggtcgaaga gttttttctt
    26161 gtcgtattct gcttcgtttg cttcgtagtc acgagcaaat ttacgagttg cgttagcgaa
    26221 tgcgatttgg cattctgtgt taacgttaac tttggcaaca ccaagtttga tagctgcttg
    26281 gatttgctca tcaggaatac ctgatccacc gtgcaatacg attgggaatc ctggaagagc
    26341 ttctgtcaat ttttgcaagt ggtcaaggtc aagaccttcc cagtttactg ggtaaggacc
    26401 gtggatgtta ccgataccag ctgccaagaa gtcgatacca gtttcaacca ttgctttagc
    26461 gtcttcgatt ggagccaatt cacctttacc gatgattcca tcttcttcac caccgatagt
    26521 accaacttca gcttctactg agataccttt agcgtgtgct ttttcaacaa cttctttagc
    26581 caatttaagg ttttcttcaa ctggaaggtg tgaaccgtca aacatgattg aagtataacc
    26641 aacttcgata cactcaagtg catcttcgta gtgaccgtgg tcaaggtgga tagctactgg
    26701 tacagtgata cccattgatt caacaaggtt agcgatcaag ttgcgagcaa ctttgtaacc
    26761 acccatgtat ttagcagcac ccattgaagt ttggatcaaa actggagctt ttttagcttc
    26821 tgctgcgcgc aagatagctt gagtccactc aaggttgttt gtgttaaatc caccaactgc
    26881 ataaccgttg tcacgggctg cttggacaaa tttttctgct gaaacgattg ccattttatc
    26941 aggcctcctg tatattttta tgggtcatcc catttacatt gttcatttta tcactttttg
    27001 ccaaaaaaat ctagtttttc ccgcagtttc gattgatttt cttctaactc catctatgta
    27061 aaccctttct ctccctagtc ttggacgact tttggaaaat ctataaagaa ggttaaacta
    27121 ttctcctcca tctcgaaacg ataagctaat ttttcatgtt ctaatagact cttaaccaca
    27181 aagagcccca taccagaccc cttgaccttg cgactggcat tgtcagaaaa agactgggct
    27241 agtttttctt gttcctctga gctacagcta ttttcgataa aaagttctcc ttctctttct
    27301 ccaattcgaa ctaagccacc tggaacagag tgcttaatgg cattgctgat gagattagaa
    27361 agaatcaact tcataactga tgggtttaga taagcctgct gatgggtcaa actattgtct
    27421 atctggagct ctctttcctt ggctagcaag gcataatctt tgaccagatt ttgcgtcatc
    27481 tggaggaggt caattgtttc cctatcatct cgcaattcct gcacagaaga gagggaaagt
    27541 atctgcagaa catggtgatt gagttcatcc acaatcccca aggcaactcc cagatactgg
    27601 tctctatcct tataacgacc gatattctct ctcatatttt cgattaggat tttcaaacta
    27661 gccagcggtg ttttcaattc atgagaagct cctcgtagga attcgacctt catcttctcc
    27721 agctggagaa tggcttcatt cttttcatgc aagtccgcaa taacagtcaa gagatgctgg
    27781 tagaggctat tgatttgttc cttgagatta cctatctcat ccttagaatc cacgcgcaat
    27841 cgcacttggg aatccaggtc catcatccga cgggtcaccc gcttgatttc caaaatcggt
    27901 gcaacaatag tccgagcgta gatgtaggcc accaaaaggg aaatcagaaa ggaggccagc
    27961 aaggtatagg gaagaaactg gagactgatt tgctccgctt ccttttgtaa atccatggaa
    28021 gctagaaact ggagaatcat agtaccaccg tcttgcgttt tcacctcgcg ctcctcaata
    28081 aagagagagg ttgtctggcg gtctgtgtcc agaggaagac tgtccttgac ttctaacttg
    28141 tcctcggtca tctcaccttt gacggtcccc ttgatatcac tagtctggga atacaagtct
    28201 aacacttgct cgatactctg cctatctttc ccttctaggg actgggcaat ggctgttgcc
    28261 ttttgaccaa tggtttcctg acgatgactc agataagtcg aaggaaaaag aaaataaata
    28321 gctaaatgaa ggcagataac cagaacacta aatatcgaga aggtatagat aaatatcttt
    28381 gcaaataaac ctgttcgttt cattttcgct ccaatttata accaacattg cgcacagtga
    28441 ggatacaatc caagtctagc tttttccgca attccttgat ataaacatca ataacacggt
    28501 caaagggaac ctcatctgtc gctttccaga cggcatcgat aatctgagat cgagtcaagg
    28561 cccggccttc atttttcact agatagtcca gaatttccaa ctctttggca ttgataggca
    28621 cttcttgacc tgcgaggctt gcactgtagc tttcaaagtc caccttggta tccttgtaag
    28681 aaaagattcg tcctgtatcg tagtagcgct tgaaaatcgc gtccaccctc acttttaaaa
    28741 gggagaggga gaaaggtttt tccagatagc catctgccaa agaggcaaag gcactcatct
    28801 tgtattcctc atcttgaaaa gctgtcaaca tcaagacagg aacctgactg gttttacgaa
    28861 tctcagctag gacttctaag ccgttgagct tgggcatctg gatatccagt aaaaccaggg
    28921 ccacctcata gctagaaaat tgctccagag cttcctgacc gtccgctgcc tcaatagttt
    28981 catagccaca atccgtcaaa taatcactga ccccctcacg gatcatctct tcatcttcta
    29041 caattaaaat tttcatactt taactgctct ctatttttta tttttcttag aataaatacc
    29101 taccctattt tctattatag tctcttgctg gccttttgtc tgcaagcaac tgaccactag
    29161 ataaaacgtt gtgaaattcc tttctcataa attccataac tttagtatat tatatttaag
    29221 cactaaagta caaagaaagc aactgaaagc aatgattttc accactgctt tcggatttat
    29281 tttgaattgt taaatagcca ttcctatcca ctattcttga atagaaacac aagatgcaat
    29341 ctttattcta gactcatttt ttcaaattta ttcaccatcc agcaagagct cttttggttg
    29401 ttttctaagg agattgcttg aagcaagcgc cataacgaga accactagaa ccaaggcaag
    29461 gacaaaaatg atgataaagt ctgatgtctg aatggaaatg tctaggctcg acaaggtctt
    29521 gctaaagcca tctacttctg caccaccacc aaggttagag gcttgagccg ccttactagc
    29581 ctgtttggca acacctgaag tcacattggc aaggacagtg tttccaattg cacgggcagt
    29641 gtaattagct aggaagtaag cagaaactag agcagggata gcaatcaaga tagattcggt
    29701 gatgaattga cccaagatac ttgcctgctt gaggccgata gagaggagaa ttcccacttc
    29761 cttgcgacgg gcgttgatcc aaaggctgag caagagggca aggaggagaa ctgagaagct
    29821 caagctaccc cagaagagga ggttggccat cttgtacata ccagagatag attgctcaag
    29881 agctgggtag ttagaggagc tcttgacgag tgtgtagctc ttccagttga taccactgat
    29941 gccattcaac tctttcataa catcatccaa gttcttgtct gctgttacaa agaaggttgc
    30001 gtccccataa atggctgtgt cttctgtgta tccataaagt tttgcagcag tgtgaatgtc
    30061 tgtaatagct gtgttttcgt aaagttcttg tgagtaggtt actgctgact tattatgacc
    30121 atcaaagagt cccttgattg tcacttcaac tgtttccttg gctccttttt cattatctgc
    30181 atcgtagata ttagagtcca gtttaacctt gtcccctact ttccagccgt gtttggctgc
    30241 caagtccttg tgcaagagga ttttatcctt gtcgtcgttg gttaagtgct ctccttcgac
    30301 tagtttataa gaaccagaga caaacttgtc ttctttagag gagtcattga cacctgtaat
    30361 catcaagcta cttccaaaac gcttggcacg atcagcagtg agattcttct tggtttctgg
    30421 cgtttcaatc aggtcatatc cagtcaaatc tccgatagcg ttgatacgtt tgacataaga
    30481 ctcaatggcc ttgttttcgg tgattttttt gatgtcttca cccttgatat tcccagcacc
    30541 acgaggcgtt ccttggttga cgcgacgatt gatttgcatg gagaagctat tggtgatatt
    30601 tttaaaggtc tcctgagaag ccttggcagt agctcccttg attgacaagc cgaccaaact
    30661 caagctcgcc atgaggagaa taatcaggaa gatgacaatc gatttgaaaa acttccttgt
    30721 aacataggca aatgcgttgt gtaacataga ttccctttct agattttgtt ttaatcattc
    30781 tattaaaata agctcaaatt atttactagt attgcgcgtt tcagtcagtt tcttatcctt
    30841 taattcaagt gtaatatctg acgcttgtgc cacttcttta ctgtgagtta cgacaatcac
    30901 acatttacct gttttctggg caagtgattt gagtagttcg acaatatctc cagcagtttt
    30961 aggatccaga tttcctgttg gctcatcagc tagaataact ggagcttctg agaccaaact
    31021 gcgagcaatg gcaacacgtt gctgttgacc acctgataac tggagaacat tccgcttgat
    31081 ctggctttca tccaaaccaa gctcaagaag tgtattcttg cttgcctttt tgttgaccaa
    31141 tcggatattt tccagcggag aaagataatc tatcaagtta taattttgaa agaccaggga
    31201 aatatggtgc atgcgatggt aagaatagcc cttcttacga atatcctctc cttgaaaaag
    31261 gatagaacct tcaacaggac tatctagacc agcaagtagg gacaagagtg tggattttcc
    31321 tgctcctgac tccccaataa tactgtaaaa ttttccgggt tcaaaattat aattgatctg
    31381 atataggact gcttcagcag tattcttata acggtaggta acatcttgta attgtaataa
    31441 agtcatgatt tctccttctt aactaataga tgataaaatt tctttcggtg attttctaaa
    31501 taagaatagg aaacaaaggg ctacagataa gcaactaagc agaactagaa aaacatagga
    31561 ttctgcaaaa gataagatgc tagttgataa actgcttgct ttggctagtg tatcttgtaa
    31621 gcttgcctga tctccacttg ctagtagagt ttggagtagg taagttgtga ttgcgtttcc
    31681 tgcaacaaat gctggaagca aagctccaag agataccaaa actacctcta aacagaattg
    31741 taggaagatc gagctcttgc cttttccaag tgcaagtaaa atccccactt catagacccg
    31801 ttctctcaac cagagagaca aaaccagaat taaggctcca gctcctgcta tcaacatccc
    31861 ataaaggaag atggtcagga aggtttggaa agttgcaact gagtctttga tttgttcaaa
    31921 agccttgttt tccttttcga cttggtagcc ttgattttcc aaggccaagt tttctacctg
    31981 cttcatgagt ccgtccattt ccttaggatt ttctacatag aagcgtgctg cactgacttg
    32041 agcttcacta ttgcccaaaa gggtttggct actttcatag tctgtaaaga cttgattttc
    32101 actgaagtca gaagacaagc ctgtgaattt ctcttgtttt ttaccagaaa agatgccgat
    32161 aatctcaaac tctactgttt gtccttttcc agattcagac tgaccagcat ccaagccaat
    32221 cttgtcatga agcgaaagac cgttcttctt agccaattct tcgtggataa ggattttctt
    32281 ggaatcccct ttttgaaggt gtcgcccttc ttttagattg aaagccgaac tggtaaaggt
    32341 tacatccttg gatgaatcct caagagccgt taagctaacc aagttattgt ctgcagctga
    32401 taaatcatca cgctccacgc tctgctcgcc agtcactgct tccttgtctt ttagttttgc
    32461 gaccgtctca agttcaggag agacattttc cagcccctta atcttgctta cagatgctag
    32521 gtctgacaac ttgaatgtct gaccattctc tatcttctta atagaaaaag atgtattgag
    32581 tgatttataa agattgcttt ctactgtttt gttggacttc atcagagtca aacaggctga
    32641 aattccggcc aataagacca ataaaatcag aaataaaata aaacttctca gtcgctttct
    32701 gctgacataa gcccaagatc tttggattgg attcatttgt cacctccata tttgtaagac
    32761 tattataaaa cccaaatatg aaatgtttat gaaatacgaa aaaaaaatat cgagtagggg
    32821 ataatctcta gcccctctca caccaccata cgtgccgttc ggcatacggc ggttcaacta
    32881 acttttaacg catgtcgttc aaggtaataa tccaaacacg aaaccagtcc acgtttttca
    32941 aggactggtt ttgatatagc acgtttaagt accgacttct gagctactat agtagattga
    33001 aactagaata gtacacctct acttctaaaa tattgttaga aatcgatttg acttccctga
    33061 tcgattcgtc ctattcttat ttcattttac tacaattgat agtggtcgcc ccagccagat
    33121 accttatctg ctatccattt aggaacccct aacttaagca atccccataa tcgtctcgat
    33181 ttcttcttcc attgcttcca gataatcact cgtaggcgag tacgcaagcg ctcatctatg
    33241 ctagtgacta tacttttcat atttataatt cattcctttc gtttcactca aggcacaaca
    33301 cagaatgaaa aagtgttgtg atctttattt tgttttataa taatagtgag aaagcctatc
    33361 actactacaa atcacgggga ggtgaataag tgagtggtac agccactacc tcgcatattt
    33421 tgtcacatca tttaacggta cataataagt tgtaccatct gaataagttg ctacaatatc
    33481 atttgcatgc tctccttcac ctttagcaaa ggttggagct cctgctggat gatttttatt
    33541 tgcctctttc aatttttcaa taatggcatt tttttctgta tcttttatat tatcaggatt
    33601 tttcactaag attttgtctg gatatgtcgg tttagcagaa acaattttta ctgttatttc
    33661 ttttttattc gaagcacttg tccagtttcc agcattatct ttagcattta attttacagt
    33721 aattcctgaa ctaggaactt cagtagcagg ttgattatca acattattca actttaattt
    33781 caaaagagct gttgcatcag acgttttatc aatcgttata tataatgatg aattgttatt
    33841 ataaccagtt tcttcatatt tagctgtttg tgagctactt gaaacagaac tgaaattatg
    33901 cccactacct ccctgattat cttcaatgct tacgtctaaa tgaacttccc cactattatt
    33961 tggcttagca acaactgtta tagtaaaata acataaaatt tgcataaata gattagggaa
    34021 atcaaagcag cttctaggaa tgttttagca gtcacagtgt actttcccag catcaagcca
    34081 ctataactct gcacataaaa atggagaaga tggcaatcct cttctccaaa tattaacttc
    34141 tttacaaacc aactatagtt gacaaagaac ctaaaatcaa ttgataacac aaggtcaggt
    34201 cggtcaactc tttcaactga agccctgtca actcttccca tttatcaatc ttgtattgga
    34261 gagaattgcg gtgcagatag agttgctggg ctgttttagt gagaacagca ctattttccc
    34321 aaagagagag aatgatttcc tgaatctgat cttgatccaa aatcatctgg tgtagacatt
    34381 ctttaattgg cttcaagtcc acgagtcttt ctcccatact ccaaagatag agctgagaaa
    34441 aagtatgaac accttggtga ccctgacgcc accatgtctt gaacaaatcc cgctcagctt
    34501 tgattaagtc tgatagggct tgatgtcctg tctgagacca aacctgaccc aacatgatag
    34561 aaagacgaag tccaaagtca tactcaaccg cttcaatcat atcacttaaa atatctgtta
    34621 cagaagtgta tttgtcttgt tgaagcacga aaacataatc ctgagctccg acctgtagca
    34681 ctgtctgaca attcggaaaa agagtccgca tcatatctag ccaagaagcc agattttcct
    34741 gctgaaaata agaaagatgg caataaacca actgaatctt tttaaaaact tgcggtgcct
    34801 gtcccttgcc ctcaaccaga taggaatacc aagggtttag cgaacgagcc tgctcctgct
    34861 gggtcaaaag ggcaaccaac tgcttttcac gctcgctgag cccagcttcc tccagcaaaa
    34921 tccactgctg agaagctaaa gggagcgtga gatagccctc tttctctact ggttggtctg
    34981 aaatccgagc atcaggaaac cagtcttgta gttctttttc cctcatgttc tagccctcca
    35041 ctttttggat gcaccatgaa accaaactct caagacgttc cagattctca gtcatatgga
    35101 gatagcccat aaccgcttca aatcccgtgg acatacgata agtcacgaca tctgcatttt
    35161 tagcctttgt gtggctattg gtattgcggc cacgtttgta gatttcttct tctttttccg
    35221 ttaggacctg ctcctccaac atgagagcaa tcaggcgagc ctgagccttg gctgacacat
    35281 acttggttgc ttcttgatgg agtttattgg gtttggtcat acctttgagg atgaggtgac
    35341 ggcgaatata catagaatac accgcatccc cctcaaaggc tagcgcaatc ccgttaatga
    35401 gattgacatc aatcacgtgt ccacctcact ccatccttgg tatcaaggag cttaattcct
    35461 tgagtaacca attggtcacg gatttggtct gctgtcgcaa agtcacgatt ggcacgcgcc
    35521 tcttggcgtt tttgaatcaa gtcttcaatc tctgcatcca aaacttcctc aacaaagaca
    35581 attccaaaaa tttctaacat atctgcaaga gcttgcttga cacttgcatc atagttccct
    35641 gagttgatcc atttggccat ttcaaagaca actgtgatac cgttggcagc attaaaatct
    35701 tcatccatag ctgctacaaa cttatcttta aagttttgta actcttgggc atccacattt
    35761 cctgtaaatg gttgttcgta agtattcttg agatacttga gattggtctc ggcatcgcga
    35821 actgcctttt ccgtgaagtt gataggctta cggtagtgct gggtcgcaaa gaagaaacga
    35881 agtacttgcc catcaagagt tttaagggca tcgtgtaccg taatgaagtt acccaaggac
    35941 ttagacattt tgacattgtc gatattgaca aagccattgt gcatccagta gttagcaaaa
    36001 gccttgcctg ttttagcttc agactgggca atttcattgg tgtggtgtgg aaactctagg
    36061 tcagctccac caccgtggat atcaatggta tcacctaaaa tctctgtcga catgactgaa
    36121 cactcaatat gccaacccgg acgtccaggt ccccaaggac tatcccaaga aatctcacct
    36181 ggtttggaag atttccatag agcaaagtct acaggatttt ccttacgagc cgtttcttca
    36241 tcggtacgac ctgaagcacc tagctccaaa tcttccaagg ttttattagc caatttagca
    36301 tagttgtggg atttttctac acggaaatag acatcccctt gactctcata ggcaaagcct
    36361 ttctcgatca agtcttccac aaaacggatg atgtctgcca taaactccac tacacgcgga
    36421 tggcgagtcg caggtttcac gcccaatgcc gtcacatcct cacgaaaggc agcgatgtac
    36481 ttatccgcaa cctcctgagg cgtgatacct tcttccctgg cacggttgat aatcttatca
    36541 tccacatctg taaaattgga aatataggca accttatacc cacggtactc aaaatagcga
    36601 cgaatggtat caaaagctac cgtcgaacgg gcgtttccta cgtggatata gttgtacacc
    36661 gttggcccac aaacatacat cttgatcttg ccgtcctcaa tcgggacaaa ttctcgcaaa
    36721 tcacgagaca tggtgtcata gattttaatc ataaatcata atcaggaaag ctgaaatcca
    36781 agaacaatta gtttcatcac taaaagttca agtaaatttc agtccgaata tctctacact
    36841 tcggaatccc ttgctccttt ctcattcaga taaaccacct gagtctgttt gacaaagcca
    36901 attttttcat acaaacgttt ggcacctaca ttgctatctt ccactgcaat ctgaaattcc
    36961 ttgtcatttt gctcaattag ttggttgacg agggattttg ctaagtagct tccatagcct
    37021 tttccacgtt caggttccaa tattgctaaa ccgtagaggt aattcgtatt agtcgataaa
    37081 tcaaccgtac aagttccaat aacctgacca gcttttaata aaatatatag tcggctttct
    37141 ggatctttca gagcttcagc gacatatcta tccacaactt ctctcgattc atgttcctct
    37201 gaaaatgcct gaaattttaa ttgactaatt tgatcctgat acgaactatc tgctaacaaa
    37261 acttcaagat gggaaacatt tgctaacgga taaggtcttc tatccttacc taaccaagtt
    37321 tctgtctctt catcctcgat tagtccccag ttactggcaa agtcaggatg attctctaaa
    37381 aaaatacgtt ctgtctgaaa agtgactgac cgaatgggga aagaagctgt ttctctctca
    37441 aaactagtaa acaatgcacg cgcaatcccc tgacggcgat gacctggatg aaccagtatc
    37501 gtcacttcta catcttggtc atctgcatag acagttaata aaccaacaag ttcgcctttt
    37561 tcataataaa ggaaaaaggc gggcatgttt gggtcaaaat taagcatgtt agagagatag
    37621 ggatcgcgat aggtaccgtc atagttttgg caacagttaa ttactttttt cgcctcagat
    37681 agctcctctt ggcttaactt gtttcttgct tgaatcatat aggtatcctc tacaaaccag
    37741 acgatctgtg actggcatct ttagcctgct cgagtttatt gacataatac tctcgttttt
    37801 cttcgacttc gtgaatgaca ggctcatctt tcttaccatg aagacggaca atcttggccg
    37861 gaataccgac aaccgtcacg tcactaggta catctgctac gacaactgct gcagcaccga
    37921 ccttggcatt ttcaccaatt tccacaggcc cgataacttg ggcatgggct gatatgaggg
    37981 ctccctttcg tacagtcgga tggcgtttgc cacagtcttt ccctgttccc ccgagagtca
    38041 ctccgtgata gagaagaacg cctttttcaa caatcgctgt ctctccaatc accagaccag
    38101 aaccatggtc aataaaaaca cctgaatcaa tctgggctcc tggatgaatc tcaatctgag
    38161 tccaaaagcg ccaaaactga ctgtacatac gagctaatag tttgaagccg tgcttccaga
    38221 gaaaatgcga gagacggtgg gccgccaagg ccttgacacc tggataagtc agcaaaacct
    38281 ccaaagtggt gcgggccgct ggatcatttt cttttacaat atcaatggtt tcgcgccacc
    38341 accccataca tttctccttt tcttattctg aatcttttga tgtttctgta aattctttct
    38401 taggtttgta atccttttga tgacgtgggc ggtgagggcg ctcagacttt tcaccttttt
    38461 catcatgctc aggttttggc ggacgaggta gaagagcctt catagaggca tcgatacggc
    38521 ctttttcatc aattttgata accttaacat caacttcatc cccgatttct accaaatcct
    38581 ctacacgatt ggtacgagtc caagccatct cagagatatg aacaagggca tctgtcttat
    38641 caaagaggtt aacaaaggca ccaaatttct cgatacgaac gactttagca cggtaaactt
    38701 catccacttt ggcttcacga accaaaccag caataatttc tttggcacgg ttaatagcat
    38761 cttggtcact agagtagata gacacatttc cttcttcgtc tatatcaatc ttaacacctg
    38821 tttcagcgat aatcttgtcg atggtttctc cacccttacc gatgacaatc ttaatcttgt
    38881 ccacatcaat cttgatcgta tcaattttcg gagcagttgg agccaattct ggacgaactt
    38941 ctggaatggt tgcttcaatg acatcaagga tttcaaaacg cgctttcttg gcttgagcaa
    39001 gagcctccgt caagatttct gcagtaatcc cttgaatctt gatatccatt tgaagggctg
    39061 taatcccatc acgagtacct gcaaccttga agtccatatc tccaaagtga tcttccaaac
    39121 cttggatatc tgtcaatact gtgtagttat ttccatctga gataagtccc atagcaatac
    39181 cagctactgg cgccttgatt ggcacaccac cagccataag ggcaagagtt cccgcacaga
    39241 tagaagcttg agatgaagaa ccgtttgatt ccaaaacttc tgctactaga cggatagcgt
    39301 atgggaattc ttccaagctt ggcaagactt gagcaagagc acgctcacca agggcaccgt
    39361 gaccgatttc acgacgacct ggcgcaccgt aacgacctgt ttcccctaca gaatattgag
    39421 ggaagttata gtggtgcata aagcgtttct tgtactctgg atccaaacca tcaatgattt
    39481 gagtttctcc catcggagcc aaggtcaaga ctgaaagagc ttgagtttgc ccacgagtaa
    39541 agagacctga accatgtaca cgaggaagga agtcaacaac cgcatccaaa ggacggattt
    39601 catcgacctt acgaccatca ggacgcacct tgtcttctgt aattaaacgt cgcacttctg
    39661 cgtgttccat ttgttccaag atttcagcca catcacgcat aatacggtca aattcttcgt
    39721 ggtccgcata tttttcttcg taaacggcag tcacttggtc tttcactact tgagtcgcag
    39781 cttcacgggc caatttctct tctacttgaa ctgccttttg gaggtcactg ttgtaggctg
    39841 caatgatttc agcttgcaat tcagcatcca cgtgaagcaa ttccacttct gctttttctt
    39901 taccgacagc agcaacgatt tcttcttgga aggcaatcaa ttctttgaca gcttcgtgcc
    39961 ctttaagaag cgcttccaac atgatttctt ctgacaattc tttggcacca gactctacca
    40021 tgttgatagc gtgcttggtt ccagctactg tcaattcaag aagagattgc tctgcttgtt
    40081 cttgacttgg gttgatgatg atttggccat ctacatatcc cacttgtacc ccagcaattg
    40141 gtccgtcaaa tggaatatct gaaatagaca gtgccaaaga tgaaccaaac atagcagcca
    40201 ttggtgcaga tgcattttca tcataagaaa gcactgtatt gatgacttgg acttcattac
    40261 ggaaaccttc cgcaaacata ggacgaatcg gacggtcaat caaacgcgct gtcaaggtcg
    40321 catctgttga aggacgtcct tcacgtttca taaagccacc aggaaacttc ccagccgcat
    40381 acattttttc ttcgtagttg acttggagtg ggaagaaatc cccagttgcc attttcttag
    40441 acataacggc agcagtcaag acagttgact caccgtaacg tacgacaaca gatccatttg
    40501 cttgcttagc aacctgacca gtctctacaa ttaactcacg acccgcaaaa gtcgtttgaa
    40561 acacttgttt tgccatttta atcccctttg gattgatgaa attatacgcc ttgcctacaa
    40621 agatcaagat accaaggacg tcaaaagcaa agtaaaaata ggaaactgac gaagtcttcg
    40681 atgaagacaa gacagtttat cttttttaca cagcttttcg gccgtgttca attacacaag
    40741 atattttgga cggttcggct tgccgaacat ttctgtagaa aaataggaag gtgacgtcgc
    40801 actcgacgag tgctaggaag cttatctttt ttcctaagaa atgagaccaa aattcaatta
    40861 ctcaagatac taagccgtca agcaactcaa aggaaaatag gaaatcgaac gacggagcga
    40921 ctgctcctag ggagatttat ctttttccac agagttgtag gcaagttcag ttttcaagat
    40981 acatcattag aaaggtttaa tactaaagta tctaaagctt tcacgctaat cgctatcggg
    41041 cgattagcta aatgctttac taactctctc gtcaaataac atcgatttga ctcactcgtg
    41101 tcgttaaatc ttacagttta aatgcattgt attatttaat accttcatct ttgtatcaag
    41161 tacgtacaga atttatttta tcatattttt cttaaaaagt gaggtcttta ccattaaaaa
    41221 ggaaccattc ccctcacctg agaagaatgg tttgctttta ttatcctaga gactggtgat
    41281 taaacaaggc atgggttgct tgatggatgt attttgctgt atcagcatta ttcatcgtat
    41341 agagatgcac accggcaata tcctgagtta ccaagtccac gatttggtcc actgcatagg
    41401 caagtcctgc tgctctgagc gactcagggt catgctcata cttgtctaag atggctttaa
    41461 atttgcgtgg aagatggata ttctcacaag tcttcaagag tcggagagcc tgatttcgat
    41521 tcagaattgg cataattcct gcatgaatgg gaacatcaat cccagccaag atgcacttgt
    41581 cctgaaaatc atagaagcgc tcattgtcaa agaagagctg agttacgagg ctcgaacagc
    41641 ctgcatccac tttcttctta agattttgaa tatctgaaat ctgatttggc gaatctggat
    41701 gcccttctgg atagcaagct ccaataatat caaagtgagg ggctcgttcc ttgataagct
    41761 caatcaagtc ggttgcatag cggaaatcct tttgtggttc cacgtctgga ataatatccc
    41821 cacgaagagc caagattttc tgcaccccaa ctttgtccaa gtcagcaata gtttcagcaa
    41881 ccttgtcctt agttagataa atagctggca agtgggcaat ggtcggaatc gccaaatcat
    41941 tttggataaa gtcagccaaa cgaaccgtcg tttccttgat attaaattta ttattgctgg
    42001 cagttacact gataaaatgg ggagccaact cctgcatatc ctgcaaggct gaaataatgt
    42061 tatcattacc cacggctggg tttggaggga acacttcaaa tgagagtgac ggtgtttggc
    42121 gtgacatatg taataacctt ttctagttga tttctttttg aacaaccact gtatggagag
    42181 aaatccaatc ttacaatttc tcacgcgcag ctttagctgc ttcaacaagg cggatcaagc
    42241 tttcttttgt ttctgggata ccacgtgttt tcaaaccaca gtcagggttg atccaaactt
    42301 tcttgcttgg cactttagca aggatgactt cgattgtgtt gtcgatttcg ccttcatttg
    42361 gtacacgagg tgagtggata tcgtaaaccc caggtcccac ttctgtttgg aagtttttcg
    42421 ctttgagttc gtccaagatt tcaaggtttg aacggctagc ttcaaaggaa ataacgtctg
    42481 catccatgtt atcgatagct gggatgatat ctgtaaattc tgagtaacac atgtgagtgt
    42541 ggatttgtgt gtctggcgct actgttgagt gtaccaagcg gaaggcagga atagcccagt
    42601 caaggtagtc ttcgtaccag tcgctacggc ggagtggcaa tttttcacga agagcagcct
    42661 cgtcgatttg gatgattttc acaccagcag cttcaaggtc aagtacttca tccttgatag
    42721 caagggcgat ttggagagtt gaatccttga tagagatgtc ttcacgtggg aatgaccagt
    42781 taaggatggt aacaggtcca gtcaacatac ctttaacagg tttgtttgta cgactttgtg
    42841 catagctaga ccatttaaca gtgatagggt taagacgagt gacatcaccc cagatgattg
    42901 gtggttttac cccacgcata ccgtatgatt gtacccatcc atttttagag aagaggtatc
    42961 ctgacaagtt ttgaccgaag tactcaacca tgtcattacg ctcaaattca ccgtgaacaa
    43021 ggacatcaaa gtcaatatct tcttgccact tgatccattc gtcaatcgtt tcagcaagga
    43081 aagcgtcgta ctctttttga gacaattcac ctttacggta agccaaacgt ttggcacgaa
    43141 cttcttttgt ttgagggaat gaaccaatcg ttgttgttgg aagagctgga agtttgaaag
    43201 cttcttcttg gatagcttca cgttctgcaa aggctggcaa acgagtgtag tctgcgtctg
    43261 tcaagccagc gatacgcgca cgaagttcag cattttcacc aacacgctca gtcgcaaaga
    43321 gttctttgtt ggctgcaaga gcttctgaac cttgaccatt tcggatagca tccaagtcac
    43381 ggatttcatc caatttttca actgcaaagg caaagtggtt caagagtgct ggttcaaatt
    43441 cttcattagc agttgtaaat ggcacatgaa gaagtgagca agagcttgtc aaaacgatgt
    43501 tttcagctgg gatttgctca agaacagtca agctcttttc gtagttgttg cgccagatgt
    43561 ttttaccatt gacaatacct acatagagag tcttgtcagc tgggaagcca cctttaacga
    43621 gttcaagagt tttcttacct tcaacaaagt caagaccgat agcatctact ggtaagttta
    43681 caaggtcagc gtatacgtca cgaacatcac cgaaataagt ttgaagcaag acttcaagac
    43741 cttttttgtc agccaagagt ttgttgtaaa ggttcaagaa aagagctttt tcttcagctg
    43801 tcaagtcttt tacaagagcc gcttcatcca attggatgcg agtcgcacca agttcagcca
    43861 atttagcaaa aacttcttgg taagcagaca ctaagctatc tacgaagtcg tctgctttca
    43921 cgccttcttc aaagtctgac aattgaagga aagtgaaggg acctacaaga acaggacgag
    43981 tgttcaatcc aagttctttg gcttcttgga actcatcgaa aatcttgtga ccagccaatt
    44041 ttacttgagt gtctttttca aatttaggaa cgatgtagtg gtagttagtg ttgaaccatt
    44101 tcttcattgg aagggcgcga acgtcccctt tttctccctg gtaaccacgt cccaaagcga
    44161 agtagcgctc aaggtcagac aagtccaagt tttgaacgga tgcaggcacc acgttgaaaa
    44221 ggaaagccgc atctaggaag ttatcatagt gagaaaagtc atttgatgga atttcagtga
    44281 tgcctttttc tttgacaatg ttccagtgtt tagcacgcaa gtcttttgct gctgctaaaa
    44341 gttcttcttc tgagatttct tttctaaagt atttttcagt tgtaaatttt aattcacgga
    44401 attcgcccaa acgagggaaa ccgacgattg tagttgacat gatgtgtcct ccaaaatttg
    44461 ttgttgaaac tatcttaaca gaaaagaaag cgtctgtata attgtaaaaa attagggttt
    44521 gatatagttt gaaactatat atctgtttcg gacaaaagaa aaagacttga agcaaacgtc
    44581 tcaaatccct tttataactt gtttttagct gtattttagt tagaatgctc aaacgcgtta
    44641 ttagtaattc ttataagtga ctatggcttg ttattagaaa agactataac tgattctagt
    44701 caacttttcc cctgttcaag tggaacgact gctagtgtct ttcctagact agctaggact
    44761 tttaagactg tgtccaactg tggactagtc ttacctgtct ccatcctagc tataacaggc
    44821 tgactcactc cactgacttc ctctagcttt ttctgactga ttccttgctt atttctggct
    44881 tcaatcaact cgctcatgat agctactcgc atatcacttt caaggatttc ctccttgcta
    44941 aagagctcag atagacatcc ttccaattac tcccaatagc actattcttc atcacttacc
    45001 cctctttctt ttagatctat gtattttttg aaaaaatgag cgaattatga ttcgatagat
    45061 tgatcagcgg gtttaaaatt gggactaact tgtttcttaa cagattttcc ttttctagga
    45121 taaagcaaat cctgtttgct taaccccaat tttccacgat gaatccaata gtaaatggtt
    45181 gaaattccca cgttaacccc tttagccata accatcattt caggcgaaaa tttttggtta
    45241 tgtatagtgg agaatctttt cctttagttc cttggtcaag cttgatttct tgaccgagcg
    45301 cttgcgattg ttttcataag actgttgagc gtagtcggca gaataaacct ctttgaagcg
    45361 cccttttcca agacattttc ggactgtccc acgcttgatt tcagtgtgga tagtttgagg
    45421 agcttttcca agtagagagg caacttctct atttgatttt ccttcttttt tccatctttc
    45481 gattaagcga cggctatcga ttgtcaaatg tttacctttt gtagtataat tgtcttgcat
    45541 ctctgtgcct tttaatcatt tcaatcttaa attggacttt ttttacttgg gttgtactta
    45601 atctataagg aagacaataa aaagaatatc aatcaagtaa agtcacaaag tcacattagc
    45661 tccgagcaac cattgcaaat tgaggtactc acacaatgat taaaacattt ctctctgccc
    45721 tttcggtcat tctcttttct atccctatca taacttattc ttttttccca tcttctaatc
    45781 ttaacatttg gctatctacc caacctatct tggcacagat ttatgccttc cccttagcta
    45841 ctgcaactat ggctgctatt ttaagtttct tatttttttc ctatcttttt acaagaaaaa
    45901 taaacaaata cggttttact ctggcatttt gctcttacta tcgctcatat tactattatt
    45961 cggaacagat aaaacccttt cttctgcatc aaataagact aaaaccttaa aattagtaac
    46021 ttggaacgtc gctaatcaaa tagaagcaca acatattgag cgaattttta gccattttga
    46081 cgccgatatg gctatattcc ctgaactagc taccaatatc agaggtgagc aagaaaacca
    46141 gagaatcaaa ctattgtttc atcaagttgg actttctatg gccaactatg atattttcac
    46201 ttctccacct accaatagtg gaatagctcc tgtgactgtg attgtcaaga aaagttatgg
    46261 tttctataca gaagctaaaa cttttcatac aacacggttc gggacaattg tattacattc
    46321 gagaaaacaa aatataccag atatcattgc cttgcatact gctcctcctc tgccaggttt
    46381 aatggaaatc tggaagcaag acttaaacat cattcataat caattggctt caaaatatcc
    46441 aaaggctatt attgcaggtg attttaatgc aactatgcgt catggagcac ttgcaaaaat
    46501 aagctctcat agggacgcat tgaatgcact tccacctttt gaaagaggaa cttggaatag
    46561 ccaaagtcca aaacttttta atgcaacaat agatcatatt ttattgccta aaaaccacta
    46621 ctatgttaaa gatttagaca ttgtaagttt tcaaaactct gatcatagat gtatttttac
    46681 agaaatcaca ttttaattat tttatataaa atcacccctc tagtgttcat aaactagagg
    46741 gggaatttgt atcctactat cgtttaacgc acttctgcat tgactttttc ttcgagagac
    46801 gcttggattt tttccatgta gcgtgcgact tcttcgtccg ttaagctgtc ttctggattt
    46861 tggaaggtca agctataagc cattgacttc ataccaagtc ccagtttttc acctgagaag
    46921 acgtcaaaga gtttgatatc tgtcaaacgt ttcacgccgg cagcttggat agcatctaca
    46981 acttcttggt gagtcacttc tgccttgagg agaagggcaa cgtcacggct gactgctggg
    47041 aatttggtga tttccacaaa tggaacagca ggttggagcg ccccttcgat ggctgaaagg
    47101 ttaagctcag ctacatacgt ttctggaata tcgtaagcct tggcagtgac tggatgcact
    47161 tggccaagga aaccaagaac ttggtcaccg agtgaaatca cggctgtacg acctggatga
    47221 aggctagcga tttcagatgt tgctgtatag gttacttgga gtcccaaacg agtaaatagg
    47281 gcttcaagga ttcccttagc atagaagaaa tcaactggaa ctgctgctgt ttggaaatct
    47341 ttttcagcaa ccaagcctgt caaggcaaag gcaaagctgt tgatctcatt tggaagttct
    47401 tcttttggat tacctgtttg ttcaaagact tttccaatct cataaagggc caagttttta
    47461 ttcttacgag ccacgttgta ggcaacggta tcaaggatcc ctgaaatcat attttgacgg
    47521 aggactgaac gatccacagt cattggccac atgagttcag taaggttact tggttgagct
    47581 gtgaactcaa ctgctttttc aggagttgtc agagcatagg tgataatttc tgtcaaacct
    47641 gctccttcag caatggtacg aacttgacgg cggagttttt gtgtcacagt caattcacca
    47701 gctgtaccat cgtcttttgg aaggctggtt ggcaagcgat catatccata gatacgagcg
    47761 atttcttcaa agagatcagc ttcgattgtg atatcccaac gacgacgtgg gactctgact
    47821 gtaaagctgt ctgcatttcc agaaagacca aagccaagac gacggaagac gtcttctaca
    47881 tcagcataag acagctcagt tccgaggaca cggttaacat cagcaagggt tgaagaaact
    47941 tctacatctg aagtatcaag ctcacccgct gaaacgatgc ccttacgcac cgtcgcacct
    48001 gcaagttccg caatcaggct agctgccgca tcaagggctt cattaactgt tgccacatta
    48061 attccttttt caaagcgaga agatgactca gaacgaaggt tcaggcgacc acttgtctta
    48121 cggatagatt tgccattgaa aacagcagct tcaaggacaa cacgactaga tttttcagag
    48181 atttctgttg cttgaccacc catgacacct gcaagggcta ctggcttgtc tgcgacagtg
    48241 atgactaggt cattcacgtc caagtcacgt tcttcaccgt ccaaggtcac caatttttca
    48301 ccagcacgcg cttcacgcac acggatgtca gtcccttcaa agttatccaa gtcaaaggca
    48361 tgcattggtt gaccaaaata gagcaggatg tagttggtca cgtccactac gttattgatg
    48421 ggacggattc cttcgttcat gagaaggttt tgcaaccatt gtggacttgg tgcgatggtc
    48481 acattgtcca agatacgagc tgcatagtaa ggcgccttgt ctgtctcaat gatgacagaa
    48541 agggcatctg ccgcagcttc attagtttct gttagagtaa attctttaaa gttgactgcc
    48601 ttgtcataga tggctgccac ttcgtgagcc actccacaca tagaaagggc atctgcacgg
    48661 tttggtgtga tggaaagttc gatgatttca tcatccaagt ctaggtaaga aaagacttcc
    48721 tcacctggca cggcatcctc aggcaagatt tggatgccat ctgcgaattc cttaggcaca
    48781 actgagtcag aaatccccaa ttcaccaagt gaacagatca ttccaagtga ctccaaacca
    48841 cggatttttc cttttttgat tttgtagtta tcagcgatac gagctcctgg aagagccacc
    48901 atgaccttga tcccagcacg cacatttggg gcaccacaaa cgatctgacg ggcttcttct
    48961 tcgccaacgt taacctgaca aacatggagg tgagtctctg gcacatcttc gcaagacaag
    49021 acctcaccga caacaatttt tgagagatca gcagctggtg attcgacact ctctacctcg
    49081 atccctgtgg ttgacatttt ttcagccaac tcctgtgatg gcacatcaat gtccaccaat
    49141 tcttttaacc atttataaga tacaagcata atttagttct ccagaatgac agttgtcact
    49201 ctagttcttt tcctttccta tcatttcaat agaagaatcc tcttcttacc ttaatttctt
    49261 tctcagtaac caatccgtat ctactttttg accaaccata aaatgatgtt ggctaaattt
    49321 ttcaaaacca tatcgattat aaaacgcttg agcttttgta ttatgctccc aaacacctaa
    49381 ccaagcccaa gaaaaactat tttttgtagc aagttcaagt gcgaattcaa acagttgctt
    49441 acctagtcca aatccttgga atttttgtag cacatagagg cgttgaattt caaaagcgtc
    49501 ctctaattct ctctcagttt gagcacttcc ccagttgact ttgagaaaac cagctatctc
    49561 ctcctcatgc ataatgaaat aggtttcaga gtcaggattt cccaactcag ttgacacagt
    49621 tttcagacta taagcctctt caaagtattc ctgtaactgc tcttccgtat tatcatacgc
    49681 aaaggtttca cgaaaggttt gtttggcaat tttagccaac acctcaacat ctgccatttc
    49741 tacttttcta atcattattt aaactgttct gagaagcgga catctccttg gtagaatcca
    49801 cggatatcgt tgattccata acggagcata gctacacgct cttgtccaag accaaaggca
    49861 aagccagagt atacagtcgc atcgatacca ctcatttcaa ggacacgtgg gtgaaccata
    49921 ccggccccca taatttcgat ccaacctgtt ttcttacata cattacagcc ttctccacca
    49981 cacttgaagc aagaaacatc cacctcaaca gatggctctg tgaatgggaa gtaagatgga
    50041 cgcaaacgaa tttgacgctc ttcaccaaac attttttgga caatcaactg aagcgttcct
    50101 tgaagatcag ccatagagat atttttccca actaccaagc cttcgatttg gtggaattgg
    50161 tgactgtggg tcgcatcgtc cgtatcgcga cggaagacac gccctggcga gatcatcttc
    50221 aaaggacctt tagaaaaatc atgggcatcc atagcacgcg cctgaactgg agacgtgtgg
    50281 gtacggagca agatttcttc agtgatatag aaagtatcct gcatatcacg agctgggtgg
    50341 tcttttggaa ggttcatacg ttcaaagtta tagtagtctt gctccacttc aaaaccatcc
    50401 acgacttgat aacccatacc gatgaagata tcttcgattt cttcactggt ttgtgtcaaa
    50461 acgtgacggt gaccagtcgc aactggacga cctggaagcg tcacatcgat actctcgcta
    50521 gccagttgag ccgcgacttt cttttcttcc aagagcttag ctgtttcttc aaaagcagca
    50581 gtcaagacat cacgagcttc attgacgtgt ttcccgatga ttggacgcat ctcagcagaa
    50641 acatctttca tccctttgag gatttcagtg agcgaaccct ttttaccaag gacagagaca
    50701 cgcaaatctt gcatctcttt ttcatttcca gcagtaatct gcttcaagct agccagcgtt
    50761 tcttcgcgaa gcgcttttaa ttgttcttca atagttgaca tatttcctcc atcagtctct
    50821 cgtagataaa aagaaaacca catgccaaaa actccactcg gagcgttgac acgcggtacc
    50881 atccgttttc atctgacaag tcagaccttc atttctaaat ccatgcgcaa gtgaattcac
    50941 ccagctttca tatagagagc ttgcagtcac ggctctcctc cctgatatac ttcccttggg
    51001 ctactagtct ttcagattcc tattcaatta ctacttagtt tatcagattt ttaccattct
    51061 tgcaagacct atcttacttc tgcttgtcag cttattctta tctaacttta tagcggattg
    51121 aaataagatg aaaacaaatc gattgggaaa gtaaaattaa tttctataaa tgttttagca
    51181 attatttcgt actattttag attcagtcta ctatatataa ccaatctatc ctaagttaac
    51241 tatttataat cggctctctg taacaaaatt aaattaatta atccccctat aaaataaaga
    51301 ggtttagaat ttgatgtctt ccaaacctct ttatttcata tttaatgaaa tgccacctta
    51361 accgtgataa tagctagtca tcaataaaaa actatttgaa taaggattct ccatttgatt
    51421 caatcactcc tttataccaa gtaaaggaca ttttcttata tcgattgaat gtgccatttc
    51481 catcatcatt tcgatcaaca taaatgagac cgtacctctt agaaagctgt gcagtggaca
    51541 tagaaacaca gtcaatacat ccccaagacg tatagcccat aatttcaaca ccatcctgta
    51601 gagcttcagc aacttgcaat aaatgttctt tcatatactg aattctataa tcatcttgga
    51661 cggttaagtt attaagttca tcttttatta gttgatcttt agcacctaat ccattttcta
    51721 ctataaataa tgggatttga taacggtcat aatatctatt taaaattata cgtagtccaa
    51781 ttggatcaat ttgccatccc cactcagaag actctaaata aggatttact aaaccaccaa
    51841 taatattccc ttctcctgaa ttatactgtg ttggaagagc agattgagtc acactcatgt
    51901 aatagctaaa ggataaaaaa tctacagtat aattttttaa taactctgca tcttcagctg
    51961 caaactctat gttaatgtca tgttccttaa aatatctttt tgcataattc ggataataac
    52021 ctctaacatg cacatctgaa aatagataat ttagattctc atactcatga gtcgcccata
    52081 catcttttgg atttggagtc attggataag ctggcatagc taataccata caccccacct
    52141 taaactctga attaatctca cgagcaattt ttgtaaccaa actcgaggcg actaattcat
    52201 gatgtatagc ttgatataat tcttgtttcg aaagattctc cttaggtata tctattcctc
    52261 cactagtaaa tggtaattcc aaaacagagt ttacttcgtt aaatgtaagc caatatttaa
    52321 ctttatcttt atacctttct aaaactgttc gagcaaattt ttcataaaaa tgaatcattc
    52381 tcctatcaac ccatccatga tattttcttg ctaaatataa tggagtctca tagtgtgaaa
    52441 gagttacaag tggttctatc ccgtgagcat gtagttcatc aaacaattca tcataatatt
    52501 tcaacccagc ttcgttaggt tcttcctcat ctccttttgg aaaaattcta ctccatgcaa
    52561 tagaagtacg aaaaacatta aagcccattt cagaaaacaa ggttatatct tccttatatt
    52621 tatgataaaa atcaatacct atcaatttta agttatcttc tgtaggattt tctgttgctt
    52681 ctcctaatcc acctttgggt aacacatcct gaactgataa gcccttacca tcttcattat
    52741 atgctccctc tacttgatta gctgcaacag ctccacccca aagaaaatca tctggaaaaa
    52801 tggtcataac tttcctccat tataatatta ccagtaattc cttagaatgc tcgattgtct
    52861 gattattagg taatactaat acatctagaa aatcattggt attcgttaca attaccggtg
    52921 taactgtttc gtagccttta gtcttgatta aattcaagtc catttcaaaa atcaactgat
    52981 ttttgaaaac tctgtctcct tcttctacat gactaataaa accttgacct tttagctcaa
    53041 cagtatctaa tccaatatga attagtaact caacaccctc atcactcttc aatccaattg
    53101 cgtgcttagt cggaaaaata tttgtaattt tcccatcaaa tggtgcataa accttacctt
    53161 cacttgggat aatcgctact ccgtctccaa ttagtttatc tgaaaatgtt ttatcctgga
    53221 catcgcttaa cggaatgatt tctcctgata taggagaaaa tatcattttt ttatttgaaa
    53281 ctccagcttt aacttctaaa ttgctagaac tctcttcttc atcgattcca aatatataag
    53341 ctaatacaaa ggtaataaca accgaaatga ccgccacaat taaagcattt acaatatttg
    53401 atggcacatc agaataaata aattgaggca acgctatcaa agatgggaca gcaaatagat
    53461 acgctttaac actagtaaga cctgcaaata atcccgctaa tccaccacca atcatagctg
    53521 cataaagcgg ttttttatat tttaaagtca caccatataa tgcaggttcg gtaatccctg
    53581 caagtaaggc tgagaaacct gctgcaaaag caatttgttt tgtattatta tttttactct
    53641 ttaatgcaac agccatcgaa gcagcccctt gagctaagtt tgaccctaac attgctggaa
    53701 gaattaatac gtctggagta gcaatagatg ccgccaaaaa aataggtgca aaagcccaat
    53761 gcattccagt cataacaata aatggcataa tagcgccaag aatagctaat gtaagccatc
    53821 cagctacacc atacatttgc ccaactagat ttgataatcc ttcaccaaca attactccaa
    53881 taggtccgac tacaactaag gcaatacagc ttgatactaa taatactagc gtaggttgca
    53941 aaaaactctt agtaacagct ggtgttaatt tagcaatcat tttttcaata tatttcatca
    54001 accaaaccat aataagaatt ggaacgactg acgaaccata actagctggt gtcacaggta
    54061 caacaaataa actaagagga ttccctgatt gcaccatttg aacaaaattt ggatggagaa
    54121 gtacacctgc tacagacata gctaatgtag atgttacttt taatttttgt gatgcagaat
    54181 aagctaataa cagcggtaag aaataatatg gagcatcccc aaaaaatgtc aaaaaagcaa
    54241 tagtctgaga atctgattgc aatataccaa gcattggtaa aataattacc aagactttca
    54301 gcatacctcc ccctaacatt gctggaatga ttggagtcat ggaaccagcg atatactcaa
    54361 tgattctttc taaaatattc cctttgtgcc cttgaacaac tgaatcggat tcaaaattgc
    54421 caagtttaac gaattcttta taataattag ctacatcatt accaagtata atttgatatt
    54481 gtccattctt tttcataata cctattacac ctggtatctt cttcacatca tcatcattga
    54541 ctaaattttc atcttttaat tctaatctta aacgtgttac acaatgggta actctattga
    54601 catttttttc gcctccaatt acatcgagga ttttttgtac cgtatcttta taactcatgg
    54661 tattctccta ttctattaat ctaaattttt tgttaagcga cgaatatgag ccatcaaata
    54721 aactaattca ctagaagtca gcaaataatt gtactccgtt tgtataaaca ttgccacctg
    54781 ttcaccacat tcatattctc taggatattt atttttcatt aatgctaaca agtcttcatc
    54841 atcatcgtca caataagttg tattttcaac caaacgatgg gcaaataatt ttatatgagt
    54901 tatgaatcta taataatcaa tagaatcttg gttaaactca gtacaataga aatcttgaat
    54961 gattttctca attcccataa ttatttcagt gattttatac gactcttgaa aattattttc
    55021 taaattagca ttaacaaaat gtagcgctat gaatgcagct tcatcaattg gaagttcaat
    55081 acctaactct ttttttatta tttgtaaagc ccttttccca agttcaaatt cttctttata
    55141 atatttcgat atttcccagc gtaggggatt cgaaataata atcccttctt tataacgttc
    55201 tatgctcgaa gaaatatgat ccgttaaatt aatatagata atttcatcaa aattattacc
    55261 caatgttatt ttacctaggt taattatttt ttcggtgatg tacaccaact ccaaaggaac
    55321 gttaataaac atctctgtaa aacgggtcat attatctcta tttttgagaa aaaaactttt
    55381 ctcaatatca attggattta ctttatctcc agtttttctt ccaaaagcta ttccccttcc
    55441 aaaaagaaga atatcgatat cttttttact ttgcgcaatt acggcattgt ggtttagtat
    55501 tcgttttatg atcataaaat ttccctttta aaataaaagg aacctactta aaaacatcaa
    55561 gaaacttctt ccgatgtgat taaataggtt cctgctcact tgtattagtg ataacatcct
    55621 tttatttcaa tttttaatgg tgacatgaag cttaaataat taataactct gtaaccattt
    55681 tcattttaag atatttcaat ctatttgtca agtacttgta gaaatttttt tattttgtgt
    55741 gattcgaatg tgataatggc aacagtctca ctaaaaaaat gaaaatcata catagaaatt
    55801 tttaaaaatt ttctctatcg taaacctgcc actagttcag aaactatact agctgattcc
    55861 aaacgtaata tggtcatctc atctaccttc cctaataatg gcattgcacc ataccaaaca
    55921 atagtcttat tcaccaaaag aataggcgtt actatttttg attgagtaaa agacacttta
    55981 attttcttgc tcttcaactg gtctagccat gctttatttg caaccgtctc tggtatacat
    56041 atctcaattt gactaatcct aaattctttt agaaaattca tcagttttgt ctggtgcaca
    56101 taaggtaaaa caagcagaca ttcctgtctt tcccctgcta agtccttcct caacacattc
    56161 tcatatctac tatcaacata aacgaattgt ttctcctcac cctcaatggc acgataatcc
    56221 atctttcgat aagctacttg tcgtttctga aacatctttt ctaaataagg aacatgaata
    56281 tccacataat cgaaaatacg taccaaagac ttatctttgt agtttctatg aatccgaccg
    56341 gcgtactgaa tcaaattatt tttccaagaa aagggcgctg ccaagatcag cgtgtccaac
    56401 tgaggtaagt caaaaccttc gccaatgtat tttccagttg acaacaatac aaacccttta
    56461 tctagctgtt ctaatatctc cagtaaactt gttctctctc ggactttggt ttttccgcta
    56521 ataatgtaac agccatcaac ctctttctct ttcaataact tttcaaaaac atctatctgt
    56581 tgaattcgat taactagaac caagatattc cgaccttctg ccacttgggc tagaatatcc
    56641 ttgagaatca actgattcct cgctgagtct gtagcaatcc aatcactgag ctgtataaaa
    56701 ttacttgctt tggtcttttc aatttccaaa tgagcaaaag aagtgaatct taattgcaat
    56761 tgccgtttaa aatccgtttc cctcttatca gcagtatgga gtatctcacc aattctctga
    56821 aaaacaatag gctcatgacc attcttacgc tcaggcgtag ccgtcaaacc gtaaagatac
    56881 ttccctctaa actgagcaac aactttttca aacatcaagg cagagacatg atgacactca
    56941 tccacaatca tcatctcata ctcatccaaa agactttgac tattttccaa cttaaataga
    57001 gattgaatca taacgacatc aaccagttta ctcagccatt tcttagtccc accgtactgt
    57061 ccaacatagc cgattacctt ttcacgacct gatgccgtat aacggatagc ctcctcctct
    57121 tcgaaagtca aaaagcagtt taagcgatct agccattggt ctaagagttg cttattatgg
    57181 actagaataa ttgtttttgt tttccgttca gagataagag cagcacctaa aacggtcttc
    57241 ccaaaacctg tcccgcatga agtaaaccat tttctttaga attcatatct gacagggcta
    57301 attcttgctc caaagtaaac tctcccttaa atgctactct aatagacctt tgtacttttc
    57361 tcctatcctc cacaactacc tgcttaaatt tatcttgcaa tggatctaac aagcctcttg
    57421 gcagccataa ataataatcg gattctccaa ataaatacat tcgctcagga atttgataga
    57481 ttggctgtcg catagcctgc tttaaatata gtaaaatgaa ataataacag gacaaatcga
    57541 tcaggaaagt caaatcgatt tctaacaatg ttttagaagc agaggtgtac tattctagtt
    57601 tcaatctact ataaaattcg ggattagaaa aggaagccat atttttcaag aaaaaaagtg
    57661 ccttggatgt cacagacgat ttttcaagtt ggatcatatt ggataaaacg accttcaact
    57721 ccttatccaa ttcttgcttg cctaactcct cttggattaa cagtgccact ttagcagttg
    57781 aaatcctctg aatttcttgt agatacctcc attgatcttc ataaggctga aactgttcat
    57841 ccacaaagac cgttcgccct tgatgataag cttctccttg aaaaggaagg gaaattaaat
    57901 tatcaaatcc acctttagga agaacatcct gatttggaaa catgcgatca aaagaatcaa
    57961 aggacagttg catactttcc tgcatagcca attctaatag tttctttcca aacaggcgag
    58021 cctttcgact cagaatcgct tcctcaaaga agaaccaaat atggagtccg taacccgaac
    58081 gagaaatctc taaatgggct tccatctggc gttccctggc tattcttcga atggttaaac
    58141 cagcttcttt ccaatctcct tcatccaaat ccagtaccaa aaaataacag ctatcatcta
    58201 agtgcatagg aaagataccg atagctgcct ccccacgaaa atgagatttc aaaacggagt
    58261 tcgtcaatgt ctggaaactc cgtttttcag gtggcaactg cttccaacca taatcatagg
    58321 aaggaaaata ctgaattttc ccttgttcat tgataaaatt cttagcataa acatcataac
    58381 gtccagcaaa cacggaggta aacaattgta atttttcttg cgtcgtcaag tgactacttt
    58441 gaagttggaa catctcctcg aaccgagagc gttccatcac aaactgactc ttgtctttaa
    58501 gacgtttaca caagaaaaac tcactatccc cattaaaaga agaaaagaca tcaagtactt
    58561 ctaccacaat tccatccaaa gacacaaaaa cagccataac aatcacctcc ttgattccta
    58621 taggctgatt ataacaagaa tggctgaaat tgtacacgaa aataaaatcc gaataacact
    58681 cattttgtat gcgaccaata gtccatctcg ctccggaatg tacgaggtaa atagagttta
    58741 aacgagcagt ctataaaatt caaaaaacgc atattatcaa gcgacctaaa actttgatga
    58801 tatacgtttt cttgtgagaa tatttacttc atttttgcct aaaattcaat gtttactcag
    58861 tatttggatt atgaaaaatc gaggtctaaa tctagataca ttttttctga agacaaatca
    58921 ttttgaccac cgagcaagag attttcaaaa aaagctgtta aaaactcaga acgtcgctgt
    58981 aaaatctttg cattatctaa taccaaggca tcacgaaaat atttggaatg ttgctgaaat
    59041 ggtgtattat caatatcaaa accaaactca cgaagatact gaatcaaaaa gaccgttact
    59101 gtccgagtgt ttccttcgcg aaatggatga atctgccaga ttcctgaaat aaaatgctgg
    59161 atttgtttaa ccacatccgc ctgagttagt gtcgcatatg caacttgttt ttcctgatta
    59221 aaatcataat ctaaggtcat ttgaatcatg gagtaatcag agtacacaac actttcacca
    59281 ttcaaaacag gttcattctt tgtgatattg gtctgacgaa attgccccac cggaatagag
    59341 ggttcaaata tatcttgaaa caactcctta tgaatagcaa gtaaagtcgc aggactgaat
    59401 ctaaaacctc ttcgagacaa gagttctacg atacgcaaag aaaccaagtc tgcctcctcc
    59461 gtactcgcat caacggtatg atgataaacc gttgcatcct cataaacctg ctcataagtc
    59521 agttcacccc gggactgttt ctcagccaaa gattccatat acgctgatgg cactagattg
    59581 tcaactttct gcagaccaaa acctatccgc cataaatcac gcttcgcttc ataagacaag
    59641 tttggattgt caatgttgta agttgattgc atagaaatat cctttcaatt gtttttctgt
    59701 gtcatcggta aattgtgaaa taggtatgga attggcgaaa attataaaaa tccttcacaa
    59761 taggttctat gaaatatata tacttcatct taatagtgag caagctaaac ttagcatttc
    59821 atgccctcat atgggatgtt ctttgactaa ataatatgat tatcgagata tatctggata
    59881 aatgaactaa taagtctgac gcgtagactt atcaaagtca ttggcataca ccactatgaa
    59941 ctcgttggtc tgttcaaatc ccaacacatt acctgagaag aaagttgcaa tgttgttttt
    60001 ggtgcgggtt tgaatttaaa aaatttgtta tgtagtacct aatctaagga attagaacaa
    60061 tgcctctaat ttttctttaa tacactgaaa cattgatgat tctggctgta tttttgaaac
    60121 agctcttctt tgctcctgga aaatatcttc agaagttata ttctctattc ctaacgctac
    60181 ttgagttttt tttctaaaat attcttttcc gttgccatct ttagaaaaat cataaccttc
    60241 cctatctacg ctgttacaca aattagctaa aaaaaactct ggggttggga aaggaagata
    60301 agaaacgtat ttagcccaat aatctataaa gcttctttgt ttcgcaatta attcaatatt
    60361 atttttttgc cctttattac ctgaaacatt aaatttaatt ggacatcccg ttatcaattt
    60421 tataatatca tcaagatttt tattatctga ttcaggaatt ttatctgata taacaacacc
    60481 attttcaaga tagttcatta aattatttga ttcactaaca ttagtgtttt gatctccatc
    60541 aagccaaaaa taatggttat cggaatctaa atacgatgag tttaaaatat tattacaaat
    60601 tatttgattt gctccaccag gaatatatct cactactaaa ttctgtttaa gattctcact
    60661 acctgaatga gtgataacaa actctagaat atatttagct agtctatctt caacataaat
    60721 catcttccta gaatgataca catcacctaa ttcaaaaaat gcatcctgat aatcaatatt
    60781 ttcaataaca tctacctttt ctccgttttt cactaaaagt ttcacggctt ctctaggaaa
    60841 atcttttata agttgtgtag aatgtgtagt gataataatt tgatgttttt tatttaaaca
    60901 ctcttgaagt aaaaactctt taaatttata gattgcactc ggatgaagtg agatttcagg
    60961 ttcatctatt aatattaatg aatttgattg cgcatttact atatcattta ctaacaaaat
    61021 aattctagcc tcacctgttc ctgcaaaagc ctcggaatat tcttttccag attttttcat
    61081 ccaaatagtt ttggaagctt ttatatcatc accttttgaa tacaacttat gtgttaaaat
    61141 ttgaatgtct gtataagatt catccattat ttcactaata atttcacaaa ctttatcatc
    61201 aactttaaca ttatctataa ccatttcctt tttataacgc gtatagctac ttgtattatt
    61261 ctttaaaata tcagcaactg gtttagatcg taatcttata aaatcttgtt tactacgttg
    61321 agtagaaatt tttttaaaat tatagtgata gaaaaataaa tcaaaagcag aaacatattc
    61381 tttacaatca caaaagacaa catttttttc aatgccatcc catctgtctg tcgaagaact
    61441 tccaatatat ttatttttgg gtaatctttc catctcatat tgtttttgag gagcatatgg
    61501 ttcccaataa tctaatcctt tttttgttcc agaacggcct ttaagaactt ctacatttct
    61561 agaagcttta atgttataat atgaatagat taaacattgt ttcccatcca cttcatctat
    61621 ttgatcaaca tttgtactaa accaatattc agacacactt ttattggctg gagaaccata
    61681 taaagcttgt aaaattgaag ttttatttac tccatttcta ccaactaata aagtaatagg
    61741 gaaattaaaa tttattcttg aatttaatga taagctcttg taatgaggaa atcgtatata
    61801 atcaatataa ggataaaatt gatttttatt tttaaaaaaa tttttagtta ttccttctaa
    61861 actctcaatt atctgattgt ccatttgcta tctccctata aactgacata aaataatttc
    61921 cactagcttg agctaatttt actggaactg cattaccaat ttgcttagct aattgacctc
    61981 tatttccaac aaaaatatag tcatcatcaa aagactgtaa tcttgcagct tctcttgcac
    62041 ttaaagctct attttgagtt gggtgcccaa atctaccttt tgaatatgac atacaccctc
    62101 ctgtaatagt aatggaaggt ttgttgatat ctaatattcc atatacgtca ctatgaccta
    62161 aacgattttt atgacaattt aattctaaag attttggcaa agaggttcta cttcccccat
    62221 tatttctaat atgagtaatt ctctcaatat ttaaattaga tagtttgttt gcaacatgat
    62281 tgtagatacc ttctccaata tattcttcac caccttcaat aggaggcaag tccattatta
    62341 tatccgcatt aatccatgaa agaaggtcca attctggtat atttgaatga gttttggaag
    62401 gcaaattcaa agttaaattc gtgttatcaa gaatttcttt tctaattccg tgtaacacca
    62461 atctttttct agattgagga actccataat cagctgtatt taaaatgtca taaataacac
    62521 tataattatt atcgattgat gtcaaaaatt ttttaaagat tttttcattt cttgttctag
    62581 tcatacccac aacattttcc attaatagaa aatcaggatt caattcatta atcaaacgaa
    62641 gaaattgaaa aacaagttga ttcctctcgt cattttcatt attagtacca atagttgaaa
    62701 aaccttgaca tggtgggcat gccacgagca ttagtttatc gtctgtatca attttaagat
    62761 actcttttac ttcatctcct gatactacat ttatatcttt atctattaca gacacctcag
    62821 gattatttaa cttataagtt ttaacagcta cggaatcaat ttcaacagca acttgaacat
    62881 ctatgcctga ttttttaagg ccacttgtag tgccacctgc accgctaaat aaatcaatag
    62941 caacaatttt ccccatagta ttctcctaaa gtttctcctt tttattataa cattatcaaa
    63001 tgtaaaaccc aacccgatag ggttaggttt ttaacatcat ttcaccaact tcttcatctc
    63061 atcaatacgt gctacggtcg catcatactt ggcttggtag tcagcttgtt tgtcgcgttc
    63121 tttttggaca acttctggtt tggcgttgac tacgaagcgt tcgttagaga gtttcttacc
    63181 aaccatgtcc agttctttct gccatttggc aagttctttt tccagacgtg ccaattcttc
    63241 ttcgacattg aggagatcgg ccagtggcag gtagatttct gctcctgtga tgacacttga
    63301 catagccagt tcaggtgcag ggatggttga tgcgatttcc aagtgttctg gatttgtaaa
    63361 gcgtttgata tagttgacat tgctgttaaa gaaggcttcc aagtcgctat cgcttgtctt
    63421 aacaaggatg gtgataggtt tgctttgtgc tacgtttact tccgcacgcg cattccgaac
    63481 agcacgaatc aagtctttga gactttccac accagtgtga gccgcaaggt cttcaaaggc
    63541 tagattaaca gttgggtatg cagctgtcac gatagaacct tctgagattt gtccaaagat
    63601 ttcctctgtc acgaatggca tgattgggtg aaggagacga aggatcttgt ccagcgtata
    63661 gaggagaaca gatcgagtaa tgaccttatc gtcttcattg tcgctgtata gaacttcctt
    63721 ggtcaactca acataccagt tggcaaattc ttcccagatg aagttgtaaa ggatatgacc
    63781 agccacacca aactcgaact tatcaaagtt ttcagtaact tttgcaatgg tttcgttgag
    63841 attgtggaga atccagcggt ccgtcacatt accagcctca cctgttgcaa cttttgtgac
    63901 attgtcatgc gccacatcca gcgtcaaacc ttcattgttc atgaggatat agcgagaaat
    63961 gttccaaatt ttgttaataa agttccatga agcatccatt ttctcgtaag agaaacgaac
    64021 gtcttgacct ggtgcggaac cgtttgaaag gaaccaacga agggcatcag caccgtattt
    64081 ctcgatgaca tccattgggt caatcccgtt accgagagat ttagacatct tgcgtccttg
    64141 ctcgtcacgg atgagaccgt ggataagcac gttttggaat ggctgacgac cagtaaattc
    64201 caaggactgg aagatcatac gagacaccca gaagaagatg atgtcgtaac ctgttaccaa
    64261 ggttgaagtt gggaaataac gtttaaagtc ttctgagtcg acttcaggcc agcccatggt
    64321 tgaaaatggc cagagggcag aactgaacca agtatccaag acgtcttcgt cctgagtcca
    64381 tccgtcacct tctggagctt cttcgccgac atacatttca ccatcagcat tgtaccaggc
    64441 agggatttgg tgaccccacc agagctgacg agagataacc cagtcgtgga cattttccat
    64501 ccattgaagg aaggtatcgt tgaaacgagg tgggtagaat tcgaccttgt cctctgtgtc
    64561 ttggttggca atggcgttct tagccaattg gtccatcttg acgaaccatt gagtagacaa
    64621 gcgaggttca accacaacac ctgtacgctc tgagtgacca acactgtgga cacgtttttc
    64681 gattttgacg agggcaccga tttcttccaa cttagcaacg actgccttac gagcttcaaa
    64741 acgatccatg cctgaaaatt caaaggcaag ctcattcata gttccgtcgt cgttcatgac
    64801 gttgacttgt ggcaagttat gacgttggcc aaccaagaag tcatttggat cgtgggcagg
    64861 tgtgattttc acgacaccag taccaaactc aggatctgcg tgctcatctc caacgattgg
    64921 gatgagttta ttagcgattg gaaggatgac gtttttacca atcaagtcct tgtagcgcgg
    64981 gtcttctgga ttaaccgcaa ccgcaacgtc cccaaacata gtctcaggac gagttgtagc
    65041 aacttcaagg gcgcgtgaac catcttccag catgtaattc atgtggtaga aggcaccttc
    65101 cacatccttg tgaatcacct caatatcaga aagggctgtg cgagctgctg ggtcccagtt
    65161 gatgataaac tcaccacggt agatccagcc tttcttgtaa aggttcacaa agaccttacg
    65221 aacagctttt gacaaacctt cgtcaagagt gaaacgctca cgagaatagt ctacagagag
    65281 ccccatcttg ccccattgtt ccttgatggt agtggcatat tcgtctttcc attcccagac
    65341 tttcgtcaag aaagactcac gaccaaggtc atagcgggaa atgccctcac cacgcaagcg
    65401 ctcctcaacc ttagcctgag tggcaatccc tgcgtggtcc atcccaggaa gccaaagggt
    65461 atcaaaacct tgcatgcgtt tttgacggat gataatatct tgcaaagttg tatcccaagc
    65521 gtgaccaagg tggagtttcc cagttacgtt tggtggtgga atcacgattg aataaggctt
    65581 agccttttga tcgcctgaag gcttgaaaac atcggcatca agccattttt ggtaacgacc
    65641 agcctcaacc tcggctggat tgtatttagg tgaaagttct ttagacatgt gtgtgtcctt
    65701 tctctatttt gtttatttta ttttgaatct gcttagcagc ttcttctgca gacaaattcg
    65761 tattatttat tttaaagtag tggttcaact cattcggttg atgttgggaa tttaattgaa
    65821 gtgtttcagc ggtctctata atttctcttt cagatacctc aatatgtcgt tttaagggtt
    65881 tgtactttaa tcgattctcc gttcgatttc gacgtatgca ctcttcaaga cttgtttcca
    65941 actcaacaaa aagaatctct tgatgataat catccaacaa actctgaatt tgctttaaat
    66001 atatcaggtg atactgattt gaaaaatcaa ttacatctgt taaaattact gatcgctgat
    66061 ttcttgcact cgctccaagg aatgaaaaag tgattccacg aacaaattcc cacatttcct
    66121 ctgtatagtc ctgatagatt tctagtgcaa aatcgatggc ttgatggtta taaaataggg
    66181 tagcatccgt cagtcgagat aattcttgac caatggtcat ttttcctgat gctggagcac
    66241 caatgatgaa aagatgcatc aaatcacctc ccattcactc ttcagcaagg catatcttaa
    66301 atcatcacag cagttgcctt gagcatcttt gcggtctctt atgcgagctt cgagggtaaa
    66361 gccaagcttt tccgcgactc gtttactttg aaggttatat ccaaagcaag ttagttcaat
    66421 cttgtgaaga cccaaatctt taaaggctaa gtcaatcaag gtacgcgcag cttctggcac
    66481 ataacctcgc ccccaatagt ctgggtgtaa ggtatagtcg atttccagca catcatcttc
    66541 atggcgatgg ttgaaatcaa cagaaccaat gactttatcg gttcctttga cgacaattcc
    66601 gtagccagcc gggaaatttt ccttttgatt gcgattggga aggatatgca ccagatagta
    66661 aatctcatct tccaaggtct tgacgggcag aaaacctgct gggtaggcga cctctggcaa
    66721 actagcatag gcatggatat cctcagcatc cgccactgtg cggactcgta aaacgagacg
    66781 ttctgtttcg attttatctg gcagctcagt tcttgccatc cttctttctc gcttttttga
    66841 tgaaactgcc cttcatatct acacgcttgt ccagatagca ataaacgcgc tgatatccat
    66901 ctcccatgaa ataggttggg caaacagttg atttttaaaa tgtccctttt catccaggag
    66961 ttctggggca acaagtcgct caagaatctt ggcaaagatg tggcaaatac cgtcttcctc
    67021 aacaatccta tctacccgac aatctaaaac aagtggacag gcgtctaaaa taggagtctg
    67081 agttcgttca gaaatttcat aatgcactcc caaacgttcc aatttctcct gatgactgat
    67141 aaaaccagcc tgctccatcg caagcataga agtttcatca gaaatattca cagtaaattt
    67201 ttgatattgt ttgatctgct ctgcggcatt ctctctcgca acgactccaa tcacaaccca
    67261 atctcctaga ctataagagg aactacaggt catgatgtta tagctaaaat tctgatcttg
    67321 atatcctaaa ataaaaacag gaaaaccata atatagttta ttagttttaa atgattgttt
    67381 tataacaacc tcctttgact aagacacaaa agaaaagccc tgccatctac atgacaggga
    67441 cgaatgtgtt tatccgcggt accacccaat ttcgggccaa gcccgcatct ttagtcttta
    67501 aaataaaaag acagaaatat ttcatttttt cagtcattag caaccagttt tgacacattt
    67561 gtggacttct cagcgctgcc actttctgta aaatgtggga ttcaaaacac ctctaatggc
    67621 tctattgtag caagtttttc tcggaaatgc aaggctcaag aaaaattact tgaacttgat
    67681 gccattttct ttcaatttct tgatggtagc tgggccgatt cctttcaagt caaggagttc
    67741 tttttcagtc cagtttttga aatctgaagc agacttgatt ccttcatcat agaaagtctt
    67801 ggcacgatca agtggaagtc cacccaagtt tgctgcaaaa tcttctacag aattagctac
    67861 tttttgagct tgctctttgg tagcttctac tgcttgttca acttttttag aaacagcctt
    67921 accagctgcg cttgctgact gttctgcacg cttcacgact ttttttgtct catctacaac
    67981 cttagtcaca gtacttgaaa aggcacctgc gcgacggagg ccatttcgta attgtttttt
    68041 acgattgagt ttctttgaca tgataaaatc ctttcaataa aaaatccctg ctctgacaag
    68101 gatttaacat aaacattcta tcaagatttt agtgaaaaat caagaatctt tctcgtttaa
    68161 taatttcgct caccaaacaa gccttctggc aaatcatgga atcccttgcc tactttgaag
    68221 ttttcaaact taccaagcaa gaactgataa gcatccaaac gactctcgta gcgaatcatg
    68281 gcatctttgg cacgctcgtc ctggtcttct tcgtaaactt tttgactttc cttgtgcgcc
    68341 atgtcgttaa tcatgatttg ggtattgacc caagcttcaa attccttcat aaattcttgt
    68401 tcgtaactca ttttttctcc ttattctaat ccacggaaat agtccgtatc aatctcacgg
    68461 tagggctgga tatcctgaac gtattccagt acaccttgga attctccgtt ttcatcgtgt
    68521 actgcagcat aggtgatgtg gacaaacttt cctcgcgact cagacttgaa ccacatttca
    68581 tacttgtcct tggtcccctc acgaagtccc ttcatgatag ccttgacctt gtccaaatac
    68641 ttaggcggat gacagagttc gacattgcgc ccgacttggg acggcgtccg tttgaaaatc
    68701 atctcatcag ctggcgtatt gtcattgtaa tactggaaaa tatcttcttt attgacaaag
    68761 gtaatctcca tagggagatg attgaggatg agattggcct gctcgactga aagatagcca
    68821 ttaccaaaag cctgttgact atggcggtcc agcacagctt ccttttcctt aggggtaaag
    68881 gtaatggtaa aatggccttc tggcgtatct atgacttgtt gaacttgacc ttctgccgta
    68941 tctagttgta caggctcctc tgcaatcttt tcctcaataa agatctgtcg ttctggcacc
    69001 catttctctg acggacggat gatggcatag ccataggcat cactctcctc cgcaatctga
    69061 agccagtcat cctgagtaaa agactcaagg agaatcatga gcaggatgga ctcttccttg
    69121 aaaatcatac tttcaaactc tgtcgcaaaa gcttcaaaag cttcctttac actgctaatt
    69181 gacacttctg gtagtgactt ggctgtcgtt agagctgttt gaaagagttc cctaatctga
    69241 tcatccactc cccacataac tttgggaggt gaatcgtgtc catagcgctc catgatagga
    69301 aagaagagtt cttccttacg ttggtaatgg atgtcaaatt gacccacaag tcccatctga
    69361 cgcaccaaac ccttacgcat ctccgccagc atttcctcgt cttccataga ctcataggta
    69421 tctaacaatc tacgaatgcg aatcaaggcc gcacggagag ccagattttc ttctttgaag
    69481 acacgaactg ggtgacctgg atgctcagta tctgaaactt cgacaccttt gatagcattt
    69541 ttaaaaagat tggcatggac atcacagagt tccataacat cttcaaaagt gacgcccgaa
    69601 tccgagttca tcagctcgtg ctccataagg gaaatctcga tggctgacac gcccgtaaag
    69661 gtcgcatcaa agcgatcttg aaccgactca ggagaggcgc cattgtgcaa ttctaacaaa
    69721 atatcccgta ggatatgaat ccgttcatct gtcattagtc taatccaatc acttcgtagc
    69781 cattcgcttc cagtgtgcgt acaatcttgt ccataggagt tcctgctagc ttagaaccct
    69841 gtttaagtga tactttacga ccaactgtat tgcgcattaa gggattggca aggggtttaa
    69901 aacccaactc cactagaatt tccaagactt ctggatgctt gtccaccact tctgcaacag
    69961 gaattgacac atcgatgata ttgtccatga cgacctccat tgtatgttct aatactcaat
    70021 gaaaatcaaa gagcaaacta ggaagctagc cgcaggt
//
LOCUS       DBERXF010000006        67218 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.06, whole genome shotgun sequence.
ACCESSION   DBERXF010000006 DBERXF010000000
VERSION     DBERXF010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 67218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67218
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.06"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..1477)
                     /gene="pcpA"
                     /locus_tag="ACL8JK_000424"
     CDS             complement(<1..1477)
                     /gene="pcpA"
                     /locus_tag="ACL8JK_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HGS1785364.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSMATGWVKDKGLW"
     gene            1812..1955
                     /locus_tag="ACL8JK_000425"
     CDS             1812..1955
                     /locus_tag="ACL8JK_000425"
                     /inference="COORDINATES: protein motif:HMM:NF016232.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1785365.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KKH"
     gene            1939..2794
                     /locus_tag="ACL8JK_000426"
     CDS             join(1939..2358,2360..2794)
                     /locus_tag="ACL8JK_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HGS1785366.1"
                     /translation="MKKNIDPYQGVNRLPAKQNYEASKQLTDARFKRLVGVQRTTFEE
                     MLAVLKTAYQLKHAKGGRKPKLSLEDLLMATLQYVREYRTYEEIATDFGIHESNLIRR
                     SQWVEVTLVQSGVTISRTPLSSEDTVMIDATEVQINRPKKELANDSGKKKCHAMKAQA
                     IVTSQGRIVSLDITVNYCHDMKLFKMSCRNIGQAGKILADSGYQGLMKICPQAQTSRK
                     SSKLKPLTAEDKAYNHALSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAG
                     IINHELGF"
     gene            complement(2873..3130)
                     /locus_tag="ACL8JK_000427"
     CDS             complement(2873..3130)
                     /locus_tag="ACL8JK_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785367.1"
                     /translation="MLPTYTDSYFLSFVSDDVEERYTENVYLDSLSVKQKFKFIFDFG
                     DEWRFECQVLREIETEDEEAYLVRSVGTSPEQYPDYDGFDY"
     gene            complement(3402..3953)
                     /locus_tag="ACL8JK_000428"
     CDS             complement(3402..3953)
                     /locus_tag="ACL8JK_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785368.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFHSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(3943..4140)
                     /locus_tag="ACL8JK_000429"
     CDS             complement(3943..4140)
                     /locus_tag="ACL8JK_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785369.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(4144..4938)
                     /locus_tag="ACL8JK_000430"
     CDS             complement(4144..4938)
                     /locus_tag="ACL8JK_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785370.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLTKGQKVVNVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(5346..5771)
                     /locus_tag="ACL8JK_000431"
     CDS             complement(5346..5771)
                     /locus_tag="ACL8JK_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785371.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(5900..6259)
                     /locus_tag="ACL8JK_000432"
     CDS             complement(5900..6259)
                     /locus_tag="ACL8JK_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGS1785372.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMALG"
     gene            complement(6305..6511)
                     /locus_tag="ACL8JK_000433"
     CDS             complement(6305..6511)
                     /locus_tag="ACL8JK_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785373.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(6498..6659)
                     /locus_tag="ACL8JK_000434"
     CDS             complement(6498..6659)
                     /locus_tag="ACL8JK_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1785374.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(7031..7987)
                     /gene="lytA"
                     /locus_tag="ACL8JK_000435"
     CDS             complement(7031..7987)
                     /gene="lytA"
                     /locus_tag="ACL8JK_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HGS1785375.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(8363..9733)
                     /locus_tag="ACL8JK_000436"
     CDS             complement(8363..9733)
                     /locus_tag="ACL8JK_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGS1785376.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFLASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(10040..11206)
                     /gene="recA"
                     /locus_tag="ACL8JK_000437"
     CDS             complement(10040..11206)
                     /gene="recA"
                     /locus_tag="ACL8JK_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGS1785377.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(11261..12517)
                     /locus_tag="ACL8JK_000438"
     CDS             complement(11261..12517)
                     /locus_tag="ACL8JK_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGS1785378.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(12602..13618)
                     /locus_tag="ACL8JK_000439"
     CDS             complement(12602..13618)
                     /locus_tag="ACL8JK_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGS1785379.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(13626..14144)
                     /locus_tag="ACL8JK_000440"
     CDS             complement(13626..14144)
                     /locus_tag="ACL8JK_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGS1785380.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(14134..14577)
                     /gene="tsaE"
                     /locus_tag="ACL8JK_000441"
     CDS             complement(14134..14577)
                     /gene="tsaE"
                     /locus_tag="ACL8JK_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGS1785381.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(14663..15283)
                     /locus_tag="ACL8JK_000442"
     CDS             complement(14663..15283)
                     /locus_tag="ACL8JK_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785382.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(15666..16529)
                     /locus_tag="ACL8JK_000443"
     CDS             complement(15666..16529)
                     /locus_tag="ACL8JK_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1785383.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            16718..16888
                     /locus_tag="ACL8JK_000444"
     CDS             16718..16888
                     /locus_tag="ACL8JK_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhrA family quorum-sensing system peptide"
                     /protein_id="HGS1785384.1"
                     /translation="MKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            17203..17499
                     /locus_tag="ACL8JK_000445"
     CDS             17203..17499
                     /locus_tag="ACL8JK_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGS1785385.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPNNW
                     GAFSNYYHGSQYHWAYVGSNGRNNQKTVYAGARSAAYAFVNTNFGEQVTFDAGW"
     gene            17602..19617
                     /locus_tag="ACL8JK_000446"
     CDS             17602..19617
                     /locus_tag="ACL8JK_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGS1785386.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEVWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLTTSTEWHDY
                     SPNGNVLIVTPHYLERQNIPVDTTIKQKMNHLNVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            19619..20251
                     /locus_tag="ACL8JK_000447"
     CDS             19619..20251
                     /locus_tag="ACL8JK_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785387.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            20392..20670
                     /locus_tag="ACL8JK_000448"
     CDS             20392..20670
                     /locus_tag="ACL8JK_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HGS1785388.1"
                     /translation="MKKFDNYIIEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(21179..21592)
                     /gene="ndk"
                     /locus_tag="ACL8JK_000449"
     CDS             complement(21179..21592)
                     /gene="ndk"
                     /locus_tag="ACL8JK_000449"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGS1785389.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEESLPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(21703..25380)
                     /gene="rpoC"
                     /locus_tag="ACL8JK_000450"
     CDS             complement(21703..25380)
                     /gene="rpoC"
                     /locus_tag="ACL8JK_000450"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGS1785390.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMSYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(25413..29024)
                     /gene="rpoB"
                     /locus_tag="ACL8JK_000451"
     CDS             complement(25413..29024)
                     /gene="rpoB"
                     /locus_tag="ACL8JK_000451"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGS1785391.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFIDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            29440..29510
                     /locus_tag="ACL8JK_000452"
     tRNA            29440..29510
                     /locus_tag="ACL8JK_000452"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29472..29474,aa:Cys,seq:gca)
     gene            complement(29708..31039)
                     /locus_tag="ACL8JK_000453"
     CDS             complement(29708..31039)
                     /locus_tag="ACL8JK_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGS1785392.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKIQITEVEIEEETE"
     gene            complement(31330..32154)
                     /gene="endA"
                     /locus_tag="ACL8JK_000454"
     CDS             complement(31330..32154)
                     /gene="endA"
                     /locus_tag="ACL8JK_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HGS1785393.1"
                     /translation="MNKKTRQTLIGLLVLLLLSAGSYYIKQNELGNQAAKTKMSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(32193..32381)
                     /locus_tag="ACL8JK_000455"
     CDS             complement(32193..32381)
                     /locus_tag="ACL8JK_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGS1785394.1"
                     /translation="MNKKSGYVIKRLLLVILVLILGLLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(32374..33657)
                     /gene="murA"
                     /locus_tag="ACL8JK_000456"
     CDS             complement(32374..33657)
                     /gene="murA"
                     /locus_tag="ACL8JK_000456"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGS1785395.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(33681..33911)
                     /locus_tag="ACL8JK_000457"
     CDS             complement(33681..33911)
                     /locus_tag="ACL8JK_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGS1785396.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(33969..35006)
                     /locus_tag="ACL8JK_000458"
     CDS             complement(33969..35006)
                     /locus_tag="ACL8JK_000458"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGS1785397.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(34990..35478)
                     /gene="coaD"
                     /locus_tag="ACL8JK_000459"
     CDS             complement(34990..35478)
                     /gene="coaD"
                     /locus_tag="ACL8JK_000459"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGS1785398.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(35468..36007)
                     /gene="rsmD"
                     /locus_tag="ACL8JK_000460"
     CDS             complement(35468..36007)
                     /gene="rsmD"
                     /locus_tag="ACL8JK_000460"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGS1785399.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(36072..37064)
                     /gene="asnA"
                     /locus_tag="ACL8JK_000461"
     CDS             complement(36072..37064)
                     /gene="asnA"
                     /locus_tag="ACL8JK_000461"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HGS1785400.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(37175..37858)
                     /locus_tag="ACL8JK_000462"
     CDS             complement(37175..37858)
                     /locus_tag="ACL8JK_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1 family protein"
                     /protein_id="HGS1785401.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(37914..38654)
                     /locus_tag="ACL8JK_000463"
     CDS             complement(37914..38654)
                     /locus_tag="ACL8JK_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGS1785402.1"
                     /translation="MTIITSKANSVVKNTKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFTLENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQREEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            38688..38966
                     /locus_tag="ACL8JK_000464"
     CDS             38688..38966
                     /locus_tag="ACL8JK_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGS1785403.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            39044..39970
                     /gene="yidC"
                     /locus_tag="ACL8JK_000465"
     CDS             39044..39970
                     /gene="yidC"
                     /locus_tag="ACL8JK_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGS1785404.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(40045..40839)
                     /gene="pflA"
                     /locus_tag="ACL8JK_000466"
     CDS             complement(40045..40839)
                     /gene="pflA"
                     /locus_tag="ACL8JK_000466"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGS1785405.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(40965..42215)
                     /locus_tag="ACL8JK_000467"
     CDS             complement(40965..42215)
                     /locus_tag="ACL8JK_000467"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGS1785406.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(42282..43109)
                     /gene="purR"
                     /locus_tag="ACL8JK_000468"
     CDS             complement(42282..43109)
                     /gene="purR"
                     /locus_tag="ACL8JK_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGS1785407.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(43376..44317)
                     /locus_tag="ACL8JK_000469"
     CDS             complement(43376..44317)
                     /locus_tag="ACL8JK_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HGS1785408.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVAHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(44307..45563)
                     /gene="rmuC"
                     /locus_tag="ACL8JK_000470"
     CDS             complement(44307..45563)
                     /gene="rmuC"
                     /locus_tag="ACL8JK_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HGS1785409.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEAAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(45565..46227)
                     /locus_tag="ACL8JK_000471"
     CDS             complement(45565..46227)
                     /locus_tag="ACL8JK_000471"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGS1785410.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKGAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(46190..46846)
                     /gene="rpe"
                     /locus_tag="ACL8JK_000472"
     CDS             complement(46190..46846)
                     /gene="rpe"
                     /locus_tag="ACL8JK_000472"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGS1785411.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(46857..47735)
                     /gene="rsgA"
                     /locus_tag="ACL8JK_000473"
     CDS             complement(46857..47735)
                     /gene="rsgA"
                     /locus_tag="ACL8JK_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGS1785412.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(47737..48609)
                     /gene="rsmA"
                     /locus_tag="ACL8JK_000474"
     CDS             complement(47737..48609)
                     /gene="rsmA"
                     /locus_tag="ACL8JK_000474"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGS1785413.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(48740..49048)
                     /locus_tag="ACL8JK_000475"
     CDS             complement(48740..49048)
                     /locus_tag="ACL8JK_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785414.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQMVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(49041..49682)
                     /locus_tag="ACL8JK_000476"
     CDS             complement(49041..49682)
                     /locus_tag="ACL8JK_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785415.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(49684..51714)
                     /locus_tag="ACL8JK_000477"
     CDS             complement(49684..51714)
                     /locus_tag="ACL8JK_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGS1785416.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRIMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEKGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(51791..52087)
                     /locus_tag="ACL8JK_000478"
     CDS             complement(51791..52087)
                     /locus_tag="ACL8JK_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGS1785417.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(52407..53306)
                     /locus_tag="ACL8JK_000479"
     CDS             complement(52407..53306)
                     /locus_tag="ACL8JK_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1785418.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(53378..53938)
                     /gene="rnmV"
                     /locus_tag="ACL8JK_000480"
     CDS             complement(53378..53938)
                     /gene="rnmV"
                     /locus_tag="ACL8JK_000480"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGS1785419.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(53938..54711)
                     /locus_tag="ACL8JK_000481"
     CDS             complement(53938..54711)
                     /locus_tag="ACL8JK_000481"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGS1785420.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(55016..55909)
                     /locus_tag="ACL8JK_000482"
     CDS             complement(55016..55909)
                     /locus_tag="ACL8JK_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall surface anchor protein"
                     /protein_id="HGS1785421.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRLVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(56193..56327)
                     /gene="rpmH"
                     /locus_tag="ACL8JK_000483"
     CDS             complement(56193..56327)
                     /gene="rpmH"
                     /locus_tag="ACL8JK_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGS1785422.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(56472..57686)
                     /locus_tag="ACL8JK_000484"
     CDS             complement(56472..57686)
                     /locus_tag="ACL8JK_000484"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS1785423.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(57842..58135)
                     /locus_tag="ACL8JK_000485"
     CDS             complement(57842..58135)
                     /locus_tag="ACL8JK_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785424.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            58297..58749
                     /locus_tag="ACL8JK_000486"
     CDS             58297..58749
                     /locus_tag="ACL8JK_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGS1785425.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(58784..60172)
                     /locus_tag="ACL8JK_000487"
     CDS             complement(58784..60172)
                     /locus_tag="ACL8JK_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS1785426.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKIVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDMLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            60238..61200
                     /locus_tag="ACL8JK_000488"
     CDS             60238..61200
                     /locus_tag="ACL8JK_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGS1785427.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVNTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(61229..61432)
                     /locus_tag="ACL8JK_000489"
     CDS             complement(61229..61432)
                     /locus_tag="ACL8JK_000489"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785428.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     SKHVFEVVDRTDEVSNHTYGKAT"
     gene            complement(61496..62506)
                     /gene="ccpA"
                     /locus_tag="ACL8JK_000490"
     CDS             complement(61496..62506)
                     /gene="ccpA"
                     /locus_tag="ACL8JK_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGS1785429.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(62931..63530)
                     /locus_tag="ACL8JK_000491"
     CDS             complement(62931..63530)
                     /locus_tag="ACL8JK_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1785430.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSVADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(63532..64629)
                     /locus_tag="ACL8JK_000492"
     CDS             complement(63532..64629)
                     /locus_tag="ACL8JK_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS1785431.1"
                     /translation="MLERLKSIHYMFWASLIFMIFPILPVVTGELPAWHLLVDILFVV
                     TYLGVLITKNQRISWLFWGIMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTIR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(64629..65366)
                     /locus_tag="ACL8JK_000493"
     CDS             complement(64629..65366)
                     /locus_tag="ACL8JK_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1785432.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(65368..66252)
                     /locus_tag="ACL8JK_000494"
     CDS             complement(65368..66252)
                     /locus_tag="ACL8JK_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785433.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(66239..66433)
                     /locus_tag="ACL8JK_000495"
     CDS             complement(66239..66433)
                     /locus_tag="ACL8JK_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785434.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(66430..66636)
                     /locus_tag="ACL8JK_000496"
     CDS             complement(66430..66636)
                     /locus_tag="ACL8JK_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785435.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        19804 a        14948 c        12243 g        20223 t
ORIGIN      
        1 accataaacc tttgtcttta acccaaccag tagccattga acctgattcg tttaagtaat
       61 accataaacc tttgtcttta acccaaccaa ctactccctg attagaattc tttttaggtt
      121 tagctacatc agtttcttgt tttatattat ctactttttc aacaatgata tcattactag
      181 tagataaatt tgatttaaga acatctttta tatgttctga tgttacatag aacttaacag
      241 tttcaggaat tgcaaatgta tcttttttca cagaaaactc tgtactttta ttcttaatat
      301 gaatttcctt taatgaatct aagacgccac ttaggaagaa ggacggcaat gagttgatat
      361 tattaccaat tgttaaactt tttaattttg gtaaaccgtt cataacgtgt ttaccaaaat
      421 ttttaacatt atctggtaat ataagttctt ttaattctaa attaccgtaa aaggctaaac
      481 gttcaatagt ttctaaacta tttggtaagc taatttcttc aagtttaatc gcatctgcaa
      541 atgcaaaagt accgattttt tctaaacctt cattcaattc gagttttttc aagtaagaat
      601 ttttattaaa cgaatatgat gcaagttctt ttgtctcctt aggcgtttta taactttcgt
      661 catttttttg acttggataa taaattaatt gggttttatc ttttgaaaac aaaacaccat
      721 caactgaggc aaacgattca tttccttctt caacatcaac atgttttaag ctagtagtga
      781 gtctaaatag attacttcct aatgttttaa ccgattttgg taatgttagt ttctctaaat
      841 ttgataaatt agcaaaagcc tcatgtgata ttaattctaa ttttgaactt gaggaaaagg
      901 ttagcttttt caatttttga ctaaaagaaa atgcacttgt tccaatatat tctagagatg
      961 caggcaattc aatctcttct aattcagaaa aatcaaaagc tctatcttca attttctcca
     1021 gctgactgcc tttgtcaaaa ataatagttt tagctttact tccatggaag cctttttttt
     1081 gtattttttt tatgcttgat gggatagtaa tagagctagg atagtagaca attctacctg
     1141 tttcatctgg ataataacta aaagcttgac tagctacttc agtaacggta aatactttat
     1201 cacctactgt gatttttgta ggaatcgtga atggttttcc atcttgacca gcttcaaact
     1261 ctacaggagt aactccatta cccacttgaa cagttcctat gttaccttct acagttagaa
     1321 ccttatattt gatattattt tgttgaataa tacttccaac tttagtctct ttgattactt
     1381 ccgaactagg agtatctgct aggattggtt cattagggac atatgctgct aaaataaccg
     1441 cagctgtagt taatgataat attgtagttt ttttcattta aatttcctta catatttatt
     1501 ttctaataga tataaaatta taactttgct agccgttgtt ataaaaagtt ttattcaatc
     1561 attatctagt agaatagagt agtacatttt ataaattgtc atctctctat aaacacagta
     1621 tatcattttt aaattttaag tcaaggaaaa ttaacccact ttaatttctt gtttaacccg
     1681 ggttaaaaaa gaaattaaag tgggttaaaa aagaaattaa ctgagtaaaa actctcgaaa
     1741 ttcaattcgc tatattatca ctcaacttga acaaatacca gaaccacaaa aaacagatgt
     1801 aaaggaaaaa tatggactta aaatttgaag gggttgattt agaatacaaa aaagctaaaa
     1861 acaatcttcc agagtctttc tgggaaacct actcagcatt tgcaaataca aatggcggga
     1921 aaataattct cgggatagat gaaaaaaaac attgacccct accaaggagt caatagactt
     1981 cctgcgaaac aaaattatga agcaagtaaa caactaaccg atgcacgatt taagcgtctt
     2041 gttggtgttc agcgcaccac ttttgaagag atgttagctg tgttaaaaac agcttatcaa
     2101 cttaaacacg caaaaggtgg acgaaaacct aaattaagcc tagaagacct tcttatggcc
     2161 actcttcaat atgtgcgaga ataccgcact tatgaagaaa ttgcgactga ttttggtatt
     2221 cacgaaagca acttaatccg tcggagccaa tgggttgaag taactcttgt tcaaagtggt
     2281 gttacgattt caagaactcc tctcagttct gaggacacgg taatgattga tgcgacggaa
     2341 gtacaaatca atcgccctaa aaaaagaatt agcgaatgat tctggtaaaa agaaatgcca
     2401 cgctatgaag gctcaagcga ttgtcacaag tcaagggaga attgtttctt tggatatcac
     2461 tgtgaactat tgtcatgata tgaagttgtt caaaatgagt tgcagaaata tcggacaagc
     2521 tggtaaaatc ttggctgaca gtggttatca agggctcatg aagatatgtc ctcaagcaca
     2581 aacttcacgt aaatccagca aactcaagcc actaacagct gaagataaag cctataacca
     2641 tgcgctatct aaggagagaa gcaaggttga gaacatcttt gccaaagtaa aaacgtttaa
     2701 aatgttttca acaacctatc gaaatcatcg taaacgcttc ggattacgaa tgaatttgat
     2761 tgctggtatt atcaatcatg aactaggatt ctagttttgc aggaagtcta ttgaaatact
     2821 aagcctacac agactgattc caattgtttt ttagatttca attttaccat tcttaatagt
     2881 caaaaccatc ataatctgga tattgttctg gcgacgttcc aaccgaacgt acgagataag
     2941 cttcttcgtc ctctgtctcg atttctctca gcacttggca ttcaaaacgc cattcatcac
     3001 cgaagtcgaa aataaactta aatttttgtt tgacacttag gctatccaga tagacatttt
     3061 ctgtgtaacg ttcttcaaca tcgtcactaa caaagctaag aaagtaagaa tctgtatatg
     3121 tcggtagcaa ccttttttaa atttgacgga aatgacccag gcttctacag atgctgactt
     3181 ttcagcttct atttcttatt ttactaattt taagtgtacc ataatacctc caagtgctca
     3241 tcgatagaat tgctcttagg aaacattcac tttctgctat tttatcataa gtttgtctaa
     3301 ctgtagcatt tgaaaccaga taattcttct gtttcacgcg aaacaccctg cgccaagcaa
     3361 ggtgttattg tttttatact caatgaaaat caaagagcaa actaggaagc tagctgcagg
     3421 ctgctcaaaa cactgttttg aggttgtaga tggaagctga cgtggtttga agagattttc
     3481 gaagagtata gaccacaatt actcaatacc gaatacccct gaatggtttc tttttcatgc
     3541 accaatatat tataataatc ttcatccaat aataaggctg ataaactagc atcttggtca
     3601 aaatataagg gaatttctcg accgtccttc tttaatggat attctggtaa aatactaaat
     3661 agttcaatca tagaatgaaa ctcaggatta gttgttgtaa atcgaaaaag ctgcgctttc
     3721 tcatctttct gacttccttg atactctccc aattctaaaa agtgattcaa ggtagtataa
     3781 aattccttat tttttacttc atcaatgatg accatatcat aatcttttgt tgtgcgactt
     3841 ttaaatcctt gcgaatccaa tacgatagag gtagcagttc ccccaatcag aacataatag
     3901 ttctgaaaat ccgcaaacat ttcttgaaaa ataactttcg tattagctgg catcatcttc
     3961 tcccagatac tgtaatatca tattttctag tgcttcactc tcttcctcta tacgtgggtc
     4021 atcatcatct tttaaggtca aataaagaga aatcggatct acaaattgtt tatcatgatt
     4081 atttttaaaa tcattccaaa actcagatac aaaaggacga tatttccata tctctagcat
     4141 ctttcatttt aaaacatgct gagaaagtgg caaggataac tgattgaatt ttctctgcca
     4201 tatgacatag ctagtatttt catccgtttc agctaaaaaa gttgaatgcg acaaagcata
     4261 agcaccacca tatagaaggt tagaaacaga ttttatctgc tttatatcgc catctggcaa
     4321 taaaatccgt tttttgatgg gattaaataa acatgacacg gattttaaga ataattcttt
     4381 ctttgacacc gtatatgtgt aaagcttatt ttgcttgttt aaccaatata aagctttaaa
     4441 agtcctcaaa cacctataaa ttgttgagtt tggaagtcca gtgacttgtg aaagcaaatc
     4501 aacatttact actttttgac cttttgtcaa taaaaaggca atccacgtta attgttcgct
     4561 aggtgttaat tccttaggga tttcagtatc attcgcattg agtactagtc ccaatggagg
     4621 gaagaagagg tttcccttaa agtctacaaa cggaactcta gcttgaagta attgcttttt
     4681 ttcactgtct gataacttcg aaaacaccaa aacaacatcc atattggctt tttcacccat
     4741 agtgcgagcc tgagtaacaa atgaactcaa actccccctt ctcttttctt taatcaataa
     4801 aaatgattcc ttatgaaaag tcatttgagt atactcaaac ctttttacaa aactgattgg
     4861 taaagtcaaa gtcagttcct caatactgac atcaacataa aaggattgaa aaattgacat
     4921 tatctttttg acattcatgt tttttcctta ttctatcatt tttattatat tttatcattc
     4981 ggtataataa aatataagtt ttttgataaa ataaccaaaa actactcgct atcccctctc
     5041 acattaccct acatatcgtt tgacatgcga ctgatagttc aggaaaactt caaggagaac
     5101 ttttctctca tccactatgc aggacttact atttcacttc tactcctata ggctcaattt
     5161 gacacttttc tttttcgaat tgctcatatg cctcctgaat agtgagttcg atttatccaa
     5221 atttattttt gtctattttg atgaatactt ccacgaagat agtctgaaaa tgaatttgca
     5281 ccaattttcc ttctcttttt aagcatatta ttccagatat gattgccctc ttattcagta
     5341 ataaattacg ctttaaacgc ttcaatcagt atatctcctg ttgtcatatg ttctaaagaa
     5401 aattcttcta catatggttt aacatctctt aggttattac ttcctaatat cccattatgc
     5461 tttttcgcta agaaaataga agtcgcttct cccttaccaa taatcttgtt actatcatga
     5521 tttcttgtta aatctctata taatgcgtat tcttcagttc caatgtctat gctcacaatc
     5581 tcagctgaac ccttagttac caactggtct atcctagatt ttaaatgggg aattgtaggt
     5641 atattgattt catcatacac ctcttgtgga ataacaattt tacccaaata gagcttttct
     5701 aaaagatgtt cagtgccaac ccataaaaat actgaaatac aatctgcatc aataaataca
     5761 cgactagtca aacgacaact cccccctctt catctagccc atatacaata tcatatctga
     5821 aagcatctag taacagttcc tcatacttcc cttgcgaaat tctgttattt tctaaaagtt
     5881 gttcagttga attaatatat tatcctaatg ccatttcttt tttactttct gacaaaggac
     5941 gatataaact tgtatcatag cctaatcttg aagctgtctc tataacacta atatccatat
     6001 ttttaatttc ttctgcatca aggtatccat cattcctcaa tctatataac atagctttat
     6061 gactgatacc ataaaactga cccaatttta taatatcttc tacttcaaga tgagttctat
     6121 tggcattttc tctgatttcc tcaaccatcc tatacagtga agatgggaaa attaaaaaat
     6181 aagaagcaaa ctgatccgct tttctttcag tttcatctcc ttcaccaatc aagataagac
     6241 tgactgaact cttcttcacc tcatcataat aaagatgata cagttcatgt gctaaagaaa
     6301 atctttacct tcctaatggc atgtctgaat tgactgcaat gagactgaac tgagttcctt
     6361 tataacagac tccgctaata ttctttccga gtccataaaa taccagcgtc aaattttcta
     6421 tcttttgtac caatttaaaa atatctatcg gcgattcacc atcagctccc aacttttttc
     6481 taagatttga agctttatta cttaaatcca ttcgtgatat tcctttcacc tttttccatt
     6541 ttggcaatca tgctttgatt caaagacaaa tactcagcaa tcttatcttg agtaagattt
     6601 gaagatattc taagttcttt tattcttttt ccaacatcac atacatttat cacatacatt
     6661 tatcacatac atttatcata ttcatacacc tctcataaaa agaatagcac actcttgtca
     6721 taatttttta aataaaaaaa ttatgacaaa acaaggaagc aatttattga tgctgcttaa
     6781 aaatctaaaa ttgatgagtt cctatcaaaa atcgtatctt caacctcaaa acagtactta
     6841 aagctatccg actcggttta cattgtcaaa tttagatttt atttgagcat aactttctag
     6901 tttgctttct gatttttgtt taatatagta gcaaacattg aaggaaatat ctccacaaaa
     6961 aaacgcatac tattaagctt tttcaagacc taataatatg cgctgttctg atttgaaaga
     7021 cattccatta ttattttact gtaatcaagc catctggctc tactgtgaat tctggcttgt
     7081 ctgccagtgt tccgtctggt ttgaggtagt accagcctgt tccgtccgct gactggataa
     7141 aggcatttga taccatggcg ccttctttag cgtctaagta gtaccaagtg tccttgtact
     7201 tgacccagcc tgtcttcatg gcaccttctt cgttgaaata gtaccactta tcagcgattt
     7261 tcttccagcc tgtagccatt tcgcctgagt tgtcgaacca gtaccagttg ccgtctgtgt
     7321 gcttcctcca gcggtctgca agcatatagc ctgaactgtc aaagtagtac caagtgccat
     7381 tgattttctc aaacttgtct tttggataag agccgtctga gtgtacgtac cagtagccag
     7441 tgtcattctt ctgccagcct gtttcaatcg tcaagccgtt ctcaatatca tgcttaaact
     7501 gctcacggct aatgccccat tttgccaagt aagggtatgg atccacatgg tctgagtggt
     7561 tgtttggttg gttattcgtg caatactcgt gcgttttaat tccagctaaa ctccctgtat
     7621 caagcgtttt cggcaaacct gcttcatctg ctagattgcg taagagttcg atataaaggc
     7681 ggtagtccgt catgaactct tctttagttg aatggctttc aatcagttca accgctgcat
     7741 aggtctcagc attccaaccg cccccaacgt cccaggcacc attatcaaca ggtcctacct
     7801 gcatgatgca accgttccca acaatgtgcg agaaaaaacc taattctggg tctttccgcc
     7861 agtgataatc cgcttcattc tgtacggttg aatgcggatt cccagttgag tgtgcgtgta
     7921 cttgcctata tggttgcacg ccgacttgag gcaaatctgt tcttaattta ctcacattaa
     7981 tttccatatt ctactcctta tcaattaaaa caactcattt tttacaatcc agaaccagaa
     8041 actcctttat ttctacctta caaagaagac aattttagtc acgattaggc ttgtagatag
     8101 aacttcaaaa cgcactattt tgacactgta aataggactg acaaggtctg cattctatct
     8161 acaataacac cccaaactaa aaagcttttc aaaagtatat ttttacagtc tctatatgtc
     8221 cttttcataa atactatact ttattatatc atataaaaga agtcaaaagt ctgttaaact
     8281 attttcaaca ccaaactaaa gaagagaaca caagtttttt cgattttcac tagaggaaat
     8341 ggattttatt cagtaaatcc aactaggatt gcactttggt tgccaaaatt gcctttcctt
     8401 cttttatcaa gggatgacgg aatagtgaga agtacagttg aactgtcatg gcaacccaga
     8461 taagaggttc acaaaggata acacccttat atcctgccca aggaataatc aaaaccacaa
     8521 aaacgatttt tccgattagt tcaataaagc tagaaactag aggaaggatc ttttgcccca
     8581 agccctgcaa gcaattgcga taaatcaaca agaggctcaa aatgggataa aaggctgaac
     8641 tgatttgcag atagagactt ccattttcta tcaagtaacc atctgtcgaa ctagccaaga
     8701 aggaaaccaa agctggactg gccaaaaaga ggaaaataca aacaaaaact gcccaggata
     8761 tacttaaacg actgccgatt cgaagacctt gaacaatacg gtcaggtcgc ttagctccta
     8821 gattctgaga agcaaaggtc gtcattgatg cagaaatagc ggtcatagga agaagggcaa
     8881 aggtcataat gcgtcgagct gccgtctggg cactaataat cactgcacca aatgtattaa
     8941 cagaaaactg taaaatcaca ctgccgatag atacaattga actcatcaag cccatagcca
     9001 aaccttgctc caagagatcc gcgtacaagc ttttgtccca tttgaaatgt ttaaactgtg
     9061 gcaagagttc tggcacactt ttacgaatat aataaaagca gagaaccgct gataaacctt
     9121 gcgaaataat ggtagcaagt cctgcggatt gaactcccag atgcaattgc gtaataaaat
     9181 agagatccag aaccacatta accaaggcag agaaaatcag aaatcccagg gctgctagac
     9241 tgtcaccaat agaccgcaac aagcctgcaa aaagattata agcaaagctg acacctacac
     9301 aggtcacaat catagaaata tattgataag attgaggaag aatttctgca ggagtatcta
     9361 agtattgcaa gagaggatac aagccaagaa agcccagcaa cataactaga atgctcaaaa
     9421 gagcacctaa aatccaagtg gctgctactg cttccttgat tttagtgaaa ttccgagctc
     9481 cataataacg agcaatgaca atccccatgc cattgccaac accaagtgta aaacctacaa
     9541 tcaggtcaaa aatcgctgtc gtcgctccta ctgcagccaa ggattcttga ccaagaaatc
     9601 gtccaacaat caagacatca gcagtgttat agagctgttg aaaaatattt gatagcaaga
     9661 ttggaaaggt gaagcttaag agcgagggaa gaatcggacc atgtatcagg tccactgttc
     9721 gttttttatt cataaagcta ttatatcagc ttcctagagg agcgacaaga aacagcaaac
     9781 ttatatatag cggaatgaaa taaggacagt caaatcgatt tttaacaatg ttttagaagt
     9841 agatgtgtac tattctagtt tcgatctatt atagttggtt gagtttggaa tagtacgctg
     9901 tagctgctaa aacatttcta gaaattaatt tgactttcct aataaagttg ttcatatctt
     9961 atttcaagct actatatata atctaaaaac ttgaatcaaa aatcgaaaaa gtagcggatt
    10021 tctccactgc tttaacagct tattcttcaa tttcgatttc aagttcatcg cctaagtcaa
    10081 gcgtaacttc ttcattcact gcttcttctt tctttggctc atcttttttg ttttcagtat
    10141 cttgttctga aacttcttct ccatcaatca agccaaattt agaacggact tgcttatcaa
    10201 tttcatcaaa gatttctggg tgctctgcca agtatttctt agcattctca gaaccttgcc
    10261 caattttttc atctttgtaa gaataccaag cccctgcttt tttgataata tccaaatcgc
    10321 ttgcaatctt caaaagctca ccagtcttag aaattccttc tccgtacata atttcaacta
    10381 cggcttcctt aaacggtgga gctaccttat tttttacaac cttaatctta gtttctttac
    10441 cgacattggt ttctttttgg tcaccagttc ccttaatttg tgtattacca cgaacatcca
    10501 agcggactga agcatagaat ttcaaagcac gtccgcccgg tgttgtttct ggatttccaa
    10561 acatcactcc aactttttca cgcaattggt tgataaaaat ggcaattgtt ttggttttat
    10621 tgatagaggc gccaagttta cgcatggcct ggctcatcat acgagcctgc aaaccaacat
    10681 ggctatctcc gatatctcca tcaatttccg cacgaggaac aagggcagca actgagtcga
    10741 ctacgacaag atcaactgca cctgagtcaa tcaattttcc cgcaatctca agaccttgct
    10801 ctcctgagtc tggttgagac aagagcaatt cgtcaatatt gacaccaagg gccgcagcat
    10861 aagctggatc aagggcatgt tccgcatcga taaaggcagc aatcccacct tctttttgcg
    10921 cttgtgcaac tgcatgaagg gcaaccgttg tcttaccaga tgactctggg ccatagattt
    10981 cgatgatacg tcccttagga taaccacctg agccaagggc aatgtcaaga gctaaagaac
    11041 ctgagctcat cacttgcacc ttttgctccg cacgttcacc caaacgcatg attgatcctt
    11101 taccaaagtc tttctcaatc aatttaagag cgtcattcaa ggccttttca cgttctgccc
    11161 caaatttttt tgaaatttct tctaattttt ttggtttttt cgccattcta ttctcctaca
    11221 ttctaatgat cctcagacct atctactatt atatcaaaag ttagtcactt aataaagcct
    11281 tgcgaactag gttaaaggca tgcataaccg caatgtgacg tacatctgct cggcttctgc
    11341 ctccaatatt aaccttgata acctcagttc cttgatcttg cgccaagcct atgaagactg
    11401 tcccaactgg gtgtccttct aggctatctg gtcctgccac tccagtcaaa ctaattccaa
    11461 aatcagactg ggtcttgctt cgtgcctgct cagccatctt ctgagctgta aattcagaca
    11521 ccacaccatg ttcttccaaa ttcttggcag gaatatccaa catccttgat ttttcctcca
    11581 agctataggt cacaaaacca cccttaaata tacttgaaac tccagaaaaa ttcgccacgg
    11641 tagcttggaa aagacctgcc gtcaaactct ctgcagccgc gatggttttc ccttgccttt
    11701 tcagttcttc taccacaatg ctggctaaac tagtttcttc cccataacca tagcaaaagt
    11761 ctcgtaaaga aattccttcg aaagtctggc agtccaagat ttgattttcc aagatatcca
    11821 gcgcttgatt cgcctcttct tgactgctag cctttgttga cagacgtaga gtgacttctc
    11881 ctgtcttggc ataaggggcc aaggtaggat cgatctgatt atcaattaaa tcagccaaaa
    11941 tcgtaaccaa ctggctctcg ccaatcccaa agaaacgaag aactcgggaa tacagcttgc
    12001 tccctgtcat caacttgggt agaagttggt ttaagaccat gggtttcaat tcacttggcg
    12061 gacctggaag gacgacatag gtcactccgt ctacttctaa ttttcctcca acagccagtc
    12121 ctgtttcgtt tggcagtgga atcgctcctt ctacaatttg agcttgtctt tcgttattcg
    12181 gtgttcgggc atagtctggt cgcagggcaa aaaagatatc caacttctcc tgagcctgag
    12241 gatcaaagac taatgctttc cctaaaaatt tagctagggt ttgtttggtt aggtcgtcct
    12301 cagttggccc caaaccgcca gtcaaaatca ccagactgct acgttgactg gcaatctcaa
    12361 gcaaagacaa gagacgaact tcattgtctc ctacagccgt ctgaaaatat acatctaccc
    12421 caatctcagc tagtttttcc gacaaaaact gggcattggt gttgacaatc tgtcctgtca
    12481 aaatctctgt tccaacagca atgatttctg ctttcatgtt tcctcctacc tatctattcg
    12541 tatttttttg aaaaaatcgc aggaattttc ctacgattga tttttttatt tgtatcaaaa
    12601 gttaattatc ttcatcacca acaggtgctc tgccaaataa atcttcaaat aaaaccgcat
    12661 tggtttcaag ctgagtaact tcttcttgtc ccaaagaacg tcggagtata ttttgcattt
    12721 ccaacatatg tgctctcgaa acaatctggt aagaaacacc ttgaagtatc tctccttcac
    12781 cctgcaactg ctgagtttca atggttttaa atgaatcttt atagcctagc aagttaggga
    12841 tactttttgc agacaaatca atattggtct gcatattgtc actcaaagct tttagaatct
    12901 cttgataatg accaacgcta tttaaactga gagctttttc catgactttt tgaataactt
    12961 cacgttgacg tttttgacga ccataatccc cctcaggatc ttggtaacgc attcgtgcat
    13021 agactagggc ttcttctccc ccaatatgtt gctccccaac accgatagaa atagtattaa
    13081 attcttcttg gtcactgata gaaattggga aacctaggat attattgact gtaatacctc
    13141 ctactgcatc cactagtttt tgcaaccctc tcatattgac catcacatag cgatcaatat
    13201 ggatattcat cattttttga atggtttcta tagcaagctc tgctccacca tctgcatatg
    13261 ctgagttcag tttcgcttca tgagcctgac cattccctga ttcaatgcgc gtcagaatat
    13321 cccgctctaa actcatcatt gttgtttttt tcgttttagg attcactgtc atcaagatca
    13381 tgctatcact tctaccgacc caagtttcag ttcgttcagc atttccggtg tccactccca
    13441 ttaacagaat ggttagaggt tcagtcgctt caataacctt ggtttcttcg ccgatttttt
    13501 tataggtttt agctaaggtt tctgtccctt gttgataaat agtataagca aaaacaccta
    13561 ctcctactac agttacagaa agtaaagcta gcaccattcc aataattttt ttaaccatat
    13621 ttctactaac ctatcagttt acccatcaag taaacatcga taaatttccc ttcttctata
    13681 tatgccccac gctcttggct accttcaatg acaaagccat gcttttgata aagatggact
    13741 gctgcttgat tacgagtttg gacagtcagt tggagacgac gcagaatgcc acttgcttgt
    13801 gcccactcta tcgcttcttc tagcaacaaa cttcccaagc cattattcca atatcttttt
    13861 ccaatcacaa tgaagagatc tccaatatga cggactctct tacgctgatc agctgtaata
    13921 tttacaatac cagcaatttt gccatttaag aatgcaagta aggttatctg attgtccgaa
    13981 ctagcttgct tgttgaggaa tatttccatc tcctcactag tcaagagaat accatctccg
    14041 tctaggctgg taaagtctgt ctccaaactc acacgattta aaaaggccac taattcagct
    14101 gcatctttgg gctctgcttc cctaatgagc aattcatact ccatattgaa gctcctctaa
    14161 caatttctca gcacgcaaac cctttgcctg aaaatttaaa cggcgtccat ctgcttcttt
    14221 tagaatttcc aattctaaat aagcatctgg caaggcatct cctaagagat ttccccactc
    14281 aataacagtc acgccgccac caaagataaa ctcatccaag tcgatagaat cagcatctcc
    14341 ttcaatacga taaacatcta ggtgataaag tggaagtcga ccctcatact ctctcacgat
    14401 agtataggtg ggacttttaa tcatttgaga aatctgtaat ccttttgcaa gtcctttagt
    14461 aaaggtcgtt ttacctgcac ccagttctcc agttaagatt aaaacatcat tctttgctaa
    14521 tagatggccc aaacgctccc ctaaggcttg caactcttct tcattttttg tgtacatact
    14581 cttattatac caaaaacttt tcttttgtgt ctattttcct actaaactta tcatcataac
    14641 atccataaaa aacaggcttt ctctaaaaga aaatgagcgt aacaatgacc aatacaagat
    14701 ctcggaaaat atgaccataa aaggaaactt ccttcttaac cgaatttggg acaagatagg
    14761 ctgcaaaaaa caagcccagt ccaatataaa tcagaagtga gacaatggtc attggatttc
    14821 ttaagaaaag aagtgttgct aaaatagtca ccaacactgt cttttttctg tccagcatag
    14881 caagaaaatc gcgcacgtat tttttcaagg gtaaaaaaat cagcaaatct agcccaaata
    14941 ggaaaaagaa ggatggcaat aaaaagtcaa ctaattcttg ctgcagcgta tttttgatga
    15001 acaagttatc tgacaaaaca agaacagctc ctaacaaatt aattaagagt aacatactgt
    15061 aaaaaagctt caccgacttc ttactggcta ggacactatg gacttcttgc ttacgagtat
    15121 aaagataatt tactccagca cagattcctg aaacgaaaac catgcttccg atgaaaaaag
    15181 ctgtactttg tttaaaggac aagatgcatt ccttccatag gaaacagcta ctcaaactga
    15241 tttgaattaa agctaacaaa aataagattc tcattgattt catcttctct ctcccttcct
    15301 accaatcatt atactaggag aaaagagaga actgtttcta atcttctcaa atgtctcttt
    15361 aagacgctaa acaaacacta gagactaata ctcaatgaaa atcaaagagc aaactaggta
    15421 gctagccaca ggttgctcaa aacactgttt tgagattgca gatagagctg acgtggtttg
    15481 aagagattta cgaagaatat aaatttgaaa tcatgaaaat ccgtcaaacg ggtggttgtt
    15541 ttgtctcgca cctcacggag cgagacggac tcagagtcac ataattataa ggctgatagt
    15601 attaatctaa ctatcagcct tacaggttat ttaacgtttc agaaaaacta taatgtcaag
    15661 attaactaaa cagtatctag ttccttcaaa taattttcta tcttcatcaa cattaaagga
    15721 ttgttataaa tcttacataa ctctcttgct tctatataat aatttttgac ttgttctctg
    15781 tctagaaatt tggctccagc atttcctaca agaataagta gaggagccaa ttggtagctt
    15841 gtctgtcttt gtttacagag ttcaatcgtt tcaagagctt cttggatggc ttcattatat
    15901 ttttcctttg atactaggta gtgagcgtag ttgtaacgaa ctctgatgta gccaaataaa
    15961 aactcttgat ggtccaaatt ttttgtctga tacaactcta ttaaatgaga gtagtttgcc
    16021 tcatattctt gttcacgacc cactaaggaa tagaaattag atagagtatt caacgccttt
    16081 aaataaatca gagtatttga agagactttt aataatatat tttccaatga agaaattgcc
    16141 tcacacttac tgtcatattg atagaagtca ataatagctt taatccattc aaggtaagtt
    16201 cggtcttcta gtgttagaaa agtacttcgt tcaatctcta ttctataaat atattccaaa
    16261 tcgtcataat ttctatcgtc taatagtcga gcagacaatt gcttgaaatt agagaggtta
    16321 gatttaattt caatttgttc attaaaaaaa taatctaatg gtacttcaag tcgttgagag
    16381 agtttgaaca aaaggtctgc ggagggaatg aaatgccctc tctcaatttt actaatctga
    16441 ctttgttcac aaattccttc tgcaagagtt tgttgggaga gtctcaactc ttttcttttc
    16501 aatctgaatt tctctgcgag tgtattcatt aaagataata aaccttccta tttgcttaat
    16561 tgcattataa aatttttagt tcaaaatagc aagttaaagg aataaataat tctttatggt
    16621 aataaactaa aaaaagtcaa aaattacata aaaatgcttg gctaaataaa atatatctgt
    16681 taaaataagg ataatgaaaa agaaaagggt ttcacgaatg aagaaaaatc gtggaattca
    16741 aaaattagct atattagtat tactaggtgt ttttatgttt agtaatacaa ttccttacca
    16801 acagtttatt cagaagaata gacaattgga gattcgagtg caatcgcaaa agaagtccaa
    16861 tggtcttgat gttgggaagg ctgattgatt tcgtattact ttaaaattca actatttaga
    16921 gaaaggtatt ctgatgagag cttgtaacaa taccagatag atataagaat ggagatgttt
    16981 gataaaatgc tttcatagct aaccaactgt tgaaaattat gagttacaaa atctaaagta
    17041 tttaagattg gtttataaaa ttaggtctct gcctgtagaa aggaacgtgc agttagaaag
    17101 gaggaaaaaa taggatacta taattcagac tgagatttct aattaaaata tatagttgca
    17161 tttcgctcat tttcataata tttcattcag aggagtaata atatgttaaa atttagaaaa
    17221 gtagttgcat catcccttgc cgttttggca tttagtttgg ctcttcctgt tttggcagtt
    17281 tctcaccgtg gtggcgagtg gacctatgga ggccatcatg atccaaataa ttggggagca
    17341 ttttcgaatt attatcatgg ttcacagtat cactgggcct atgttggaag taatggacgt
    17401 aacaatcaaa aaacagttta tgcaggagca cgtagtgcgg cctatgcgtt tgttaataca
    17461 aattttgggg agcaagttac atttgatgcg ggatggtaaa gaataattga agaagattct
    17521 tttatcaata gttcagtaag cttgttagtt tatagagggc aggagtattt ctgccctctg
    17581 ttttagaata aggaatgcac tatgaaaaaa ttatttatac tcatatccaa cctgcttgct
    17641 agtttgttct ttgtttgggt atttaccatt tggactgata catatgtctc ccattattac
    17701 cccaacgttg ttgtacgtga ttcttcccct gaaacaactt ttcagcatgt tgctacacgc
    17761 ttggaaaaac tagcagaaga aacagatagc tttattgcga ttcaacacca agatcctaac
    17821 tcagaaggta ctacagtttt ttcttatacg acctttgggg acggaaagtt gcctgatggg
    17881 cttcaggaaa aaaatctaga agatgctcaa agtagtagtg ttgaaacaaa ctattttgta
    17941 ttcgatggac acctagatat tcacttgcta agggaagagc taagtcaact tggcttgact
    18001 aacatgcacc tgacaattcc atctaaacta tctacgttaa tggctatctt tagtaacgga
    18061 tttcagttaa tcagtctatt gattttcatc ttaacctttg tagcactgac tttaattagt
    18121 caaattagcc aattacggtc atcgggcatt cgcctcattt caggagagaa acggtggtcc
    18181 attttcctta gaccagttgg tgaggatttg aaagggatag ctgttggttt cagtttagct
    18241 ggcgtgctcg ccattcttat gcaaaaaatt ctgtcgcttc caacgcaatc cctaatgacc
    18301 ataggagcag gcttgctcag ttataatctc atcttgttgt cgatctccct gtttttcgct
    18361 caactcttcg cagttgggat aaaaaagata cacctgatgc agattataaa agggcaagtg
    18421 cctgtcagag gaatcattag tttgatttta atcggtcaac tgttagcgat tattattgta
    18481 acgctgggaa tagggagtag cttaaagtat tcccaagcct ggcaacagca tcggattgga
    18541 caagaggttt ggagtcagga aagacaactg attaccctat caatcagccg tgaaggaacg
    18601 agtcctggtt ttgatgaaca agctcaaagg aaactcagaa cttggtatca attgatggat
    18661 ctggctgttt cagaacaaaa ggctttctta tctagacacc agttaattga ccgtactttg
    18721 caaaatggca tggcttcctc caaaaacttg acaacctcta cagaatggca cgattacagc
    18781 ccgaatggca atgtccttat cgtcacaccg cattacttgg agcgtcaaaa cattcctgta
    18841 gatacaacta ttaagcaaaa gatgaatcac cttaatgtag gggagtttgt cttattgctg
    18901 cctgaacacc tccgttcaga ggaagaacat tataaatctg tttttgaaga cgacttaacc
    18961 agtcgcatgt ctagtcaaga tgaacgacag caaatgactg ctacggtagg ttatttagaa
    19021 tcaggtcagg atcgttttgt gtataatacg acccctattt cttaccagca gtttttgaaa
    19081 gatccaatca tcattgttat aacaccccaa tcaactggtc cacagtccat tttgttttgg
    19141 atagacgcag tacagaacta cgttctcttt aatcaattgt ctgatgccca ggagcttatc
    19201 cagagacaag gcattgaaaa ttgggtctca gaaatgcaaa caggttacca caactacatc
    19261 acattattgg ataatatcca gagggaacgt tgggtaatgc tagcaggagc tgtgcttggg
    19321 attgcaactt caatcttgtt gtttaacact atgaataggc tctactttga agaatttaga
    19381 cgtgccattt ttatcaaacg cattgcaggt ctcaggttct tagaaatcca tcgcacttat
    19441 ctctttgctc aactgggtgt gtttttactg ggatttgttg cgagtgtatt tcttcaggta
    19501 gagataggag ttgctttctt agtcttgtta ctctttactg gtctatctct tttacagtta
    19561 catgtccaaa tgcagaaaga aaacaagatg tccattcttg ttttgaaggg aggttaatat
    19621 gattgaactt aaacaggtga gtaaatcttt tggagaacga gagttatttt cgaatctttc
    19681 aatgacattt gaggctggaa aagtctatgc cttaattggt tcaagtggta gcggaaaaac
    19741 aaccttgatg aacatgattg ggaaattaga accttatgat gggacgattt tttaccgagg
    19801 taaagacttg gccaattata aatcgagtga ttttttccgt cacgaattgg gctacctctt
    19861 ccagaacttt ggcttaattg aaaaccaaag tattgaagaa aaccttaagc taggtctcat
    19921 tggtcaaaag ttgagtcggt cggaacagcg gttgaggcag aagcaggctt tagaacaggt
    19981 cggcctggct tatcttgacc tagataagcg catctttgag ttatcgggcg gagaatcgca
    20041 acgagttgcc ttggcaaaaa ttatcttaaa gaatccaccc tttattctgg cagatgagcc
    20101 aacagcttca atagacccag caacctctca gttgattatg gagattttgc tatctcttcg
    20161 agatgataat aggctaatca ttatcgcaac acataatccg gcaatttggg agatggctga
    20221 tgaagtgttc acgatggatc atctgaaata aaaatccttg tttttaattg cacgatgagt
    20281 tactgaaata ttatcatgaa tcaataattg gagttaattt agaattgtac tttattaata
    20341 ttgaggtaac tttttcttga taaaggagga aatagtggag aggaagttag aatgaaaaaa
    20401 ttcgacaatt atattattga gaagccttgc gattctaatt cagataaact gcaaaaaatc
    20461 ttaataattg aaaatttggt agatgatatt ttgcaatttc ctctcagaat caataatagt
    20521 gtaggagaga ttttcctcct acaaccgttt caaaagaaaa ctatctttat tccatgttat
    20581 tttgaggaag atattgtgaa agtcaaagat gatgataaag ttgagtggaa tttgttagaa
    20641 tttcaaaaat ttagagcatt tttggcttag taatctgtgt tgaaggctca aaacctatgg
    20701 taaaaaagtc gctttgaaaa cgtattgcct ccaaagattt agttaaataa tgatttaaca
    20761 caaaaagaaa ttattgaagt tctggaaaga tgttgtttca gtattgagaa aaggtgggaa
    20821 aaacttgcga ttttcacaga gaaaggaaga aaaagtatag aaatatagtc aattgaaaca
    20881 agaacaggac aaaagaacct tttgtgccat atttttctcc tttcgcttta caattggctt
    20941 gaacaccttt attgtatcgc gtttggagtt tttttggtat aaccttcgac gcgcacccgc
    21001 atagcgggtg tttttttgtc tcgcacctaa cggagcgaga cgaactaata gtcacttaat
    21061 caaaaaacgc accatatcaa aaactaaaaa gtttgatatc atgcgtcatg tcttaaacta
    21121 attgactata ctttctattc aaatgagctt ttaaccaatt gattgagcca atccactctt
    21181 aaaaccaaag agcaatttct cgcttagctg actcttctga atctgaacca tgtacaacat
    21241 tttggataac ctcattttct ccagcagctt ttgcaaagtc acctcgaata gtgcctggta
    21301 aagattcttc tggacgagtt gcacccatca tggtccgcca agtttcgatt actttgggac
    21361 cagaaatgac acccacaaga actggacctg aagtcatgaa ttcacgaatc ggtaggtaaa
    21421 aactctgacc aaccaagtcc tgatagtgct ggtcaatcaa ctcttctgaa acctgtgaac
    21481 gaaactccaa tttttcgatt gtaaatccac gttgttcgat gcgctttaac acttcaccca
    21541 ctagccctct ttttacacca tctggtttga tgataaagaa tgtttgttcc atacccgtct
    21601 cctttgtcag cttctttctt ttattttacc acatttcgtg gaaaaatgga gaaagttttc
    21661 agaagagaga atgagagaac ccgagggttc tctcattctc tcttattcta ctgtttcttc
    21721 cacagtttca acggcagtat ccacaactac ttctgttgtt tcttcatttc cttcttcctc
    21781 tactggagga ttaaggtatt cttcttcgtt gacagcatgt ggttcaaggt tacggtaacg
    21841 ggccatacca gtaccagctg ggatgatctt accgatgata acattttctt taagtccaag
    21901 gagatggtct ttcttaccac ggatagctgc gtcagtaagg acacgagttg tttcttggaa
    21961 ggaagctgct gacaagaaac tgtttgtttc aagtgaggct ttggtaattc ccataaggac
    22021 tgggcgacct gtcgctggaa ctccacctgc gataaggaca tctttgttgg catctgtaaa
    22081 gtcattgata tccatgaggg tacccatgag aagatctgta tcacctggat ccatgacacg
    22141 gactttacgg atcatttgac gaaccattac ctcgatgtgt ttgtcaccga tttctacccc
    22201 ttggctacgg taaacttttt gtacttcacc gagaaggtac gtttcaactg acaagacatc
    22261 acgaactgca aggagacgtt ttggttggat agaaccttct gtcagagcag caccacgcgc
    22321 tacttggccc ccaacttcga cacgcatacg agctgtaaat ggaacgacat attcaccttc
    22381 gccagtttca cccttaacaa agactttctt ggtacgagtt gatgcatctt cttcgatagc
    22441 agtaacttgt cctttaacct ctgtgataac cgcttcccct ttaggattac gggcttcaaa
    22501 gatttcttgg acacgaggaa gaccctgagt gatatcggta tttgaggcaa ccccacctgt
    22561 gtggaaggta cgcattgtaa gctgtgtacc aggttccccg atagattggg cagcaattgt
    22621 accaactgct tcaccaactt caaccgcatc accagtcgcc aagttgatac cgtaacagtg
    22681 acggcagaca ccgtgacgag tgttacatgt aaatacagaa cggatagtca cttcttccac
    22741 accagcattg acaatttcac gcgccttgtc ttctgtaatc aattcatttg gaccaataat
    22801 cactgcacca gtttctggat gtttaacagt tttcttagtg taacgaccgt tgagacgctc
    22861 ttcgagagac tcgatcatct cttttccttc tgcgatagaa cggatcaaga gaccacggtc
    22921 agttccacag tcgtcctcac ggatgataac gtcttgggca acgtcgacca aacgacgagt
    22981 caagtaacct gagtcggctg tcttaagggc cgtatcggtc atacctttac gagcaccgtg
    23041 agttgagaag aacatttcca ataccgacaa accttcgcgg aagtttgaaa ggattggcaa
    23101 ttccatgata cgtccattcg gagcagccat cagaccacgc ataccggcaa gctgtgagaa
    23161 gtttgagatg ttaccacggg ctccagagtc catcatcata acgattgggt tcttaggatc
    23221 ttgattagca atcaagcgtt tctcaagttt ttcacgggca gcacgccatt cagctgtaac
    23281 agcattgtaa cgctcgtcgt ctgtgatcat accacgacgg aattgtttgg tgatttgttc
    23341 gacacgtttg tgtgattctt caatgatttc agccttgtca tcaacgactg ggatatcggc
    23401 aatacccact gtcaatcctg caagagttga gtggtggtaa ccgaggttct tcatgcggtc
    23461 aagtagggca gaagtttctg tcgtacggaa acgtttgaag atttcagcga tgatatttcc
    23521 gaggtttttc ttcttgaatg gagggttgag ctcaagattg ctgatagctt ccttgatatc
    23581 tccaccaagt ggcaagaagt atttagctgg aacaccttct gtcaagttgg cattgtttgg
    23641 ttcttgcaag tatggtagcc cctctggcat gatatcgttg aagagaattt taccaactgt
    23701 tgtaagcaag accttatgtc tttgctcttc tgtccaaggc ttgttgaggc tgtctgttgc
    23761 gataccaaca cgtgagtgga ggtgaacata accattgcgg taagacataa ccgcttcgtc
    23821 acggtctttg aagaccattc cttcaccttc gcgaccagct tcttccatgg tcaagtagta
    23881 gttacccaaa accatgtcct gagatggagt aactaccggt ttcccatctt tcgggttcaa
    23941 gatgtgctca gcagctagca tgaggatacg agcttctgct tgtgcttctt ctgaaagtgg
    24001 tacgtggatg gccatttggt ccccgtcaaa gtcagcattg taggcttcac agacaagtgg
    24061 gtgcaagcga agagccttac catcaattaa gactggctcg aaggcttgga tacccaaacg
    24121 gtgaagggtc ggtgcgcggt tcaaaagcac tgggtgttct ttaatcactt cttcaaggat
    24181 atcccagata cgctcatctc cgcgttccac caagcgttta gctgctttga cgttttgcac
    24241 gatatcacgg gcaacgattt cacgcatgac aaatggttta aagagttcaa tcgccatttc
    24301 acgtggcaca ccacattggt acatcttaag agttggacca acggcgataa ctgaacgtcc
    24361 tgagaagtca acacgtttac cgagcaagtt ttgacggaag cgtccttgtt tacctttaag
    24421 catgtggctc aatgatttca atggacggct acctggtcct gtgattggac gaccacgacg
    24481 accattgtca atcaaagcgt caactgcttc ttgaagcata cgcttctcat tttgaacgat
    24541 gatacctggt gcatttaact caagcaaacg agccaaacgg ttgttacggt tgataacacg
    24601 gcggtaaagg tcattcaagt cagatgaggc aaaacggcca ccatccaact gcaacattgg
    24661 acgaagatct ggtgggataa ccggaaggat gttaagaatc atccattcag gtttgtttcc
    24721 agacttgtaa aaggcatcca aaacatccaa acgacggatg gctttgacac gtttttgtcc
    24781 agtagctgtt ttcaattctt ctttgagttc agcaatttct ttttcaagat ctacttgctt
    24841 caaaaggtct tggatggctt ccgcacccat cttggcaaca aatgaaccat aaccatattc
    24901 acgcaagcgc tctcggtatt cgcgctctgt catgatagac ttgtgctcaa gtggtgtatc
    24961 cttaggatca atcaccacat aagccgcaaa gtagataact tcctcgaggg cacgagggct
    25021 catatcaagg gtcaagccca tacggcttgg aatccccttg aagtaccaga tgtgagatac
    25081 aggagctttc aattcgatat gtcccatacg ctcacgacga actttcgtac gcgttacttc
    25141 aaccccacag cggtcacaaa caattcctct gtaacgaatg cgtttgtact taccacaagc
    25201 acattcccag tcttttgtag gaccaaagat cacttcatca aagagtcctt cacgttctgg
    25261 tttcaaggta cgataattga ttgtttcagg ttttttgact tctccataag accatgaacg
    25321 gactttactt ggagaagcta gggtgatttg catactttta aaacgattta catcaaccac
    25381 tatttcttcc ctttctattc taagtgaact gcttattctt gttcagcagc ttcttctgtt
    25441 gcttccgctt ttgttgcttt ctcagcttct tcagcttcaa aggctgcttt agcctcttgg
    25501 gctgcttttt cgcgggcttt ttcaaggtca tctacgtgga tgacatcttc gtccattcct
    25561 tcatccaagt cgcgaagttc cacttcttgg tcatcttcgt ctaggacacg catgtcaaga
    25621 ccaagagatt gcaattcttt gacaagaact cggaaggatt ctggaacacc tggttttgga
    25681 attggtttgc cttttgtaat agcttcatag gctttcaaac gtccgttgat atcgtccgac
    25741 ttgtaagtca agatttcttg aaggacattt gacgcaccgt aggcttcaag agcccaaacc
    25801 tccatctcac cgaaacgttg tccaccaaac tgagctttac ctccgagtgg ttgttgggta
    25861 acagttgagt aaggtccgac tgaacgcgca tgcaatttat cgtcaaccat gtggtggagt
    25921 ttgatcatgt acatgactcc aacagaaaca cggttatcaa atggttcacc tgtacgtcca
    25981 tcgtaaagga ttgtcttggc atcgctatcc atacctgctt ctttaacagt tgaccaaaga
    26041 tcttcagaac ttgctccatc aaagactggt gtcgcaatgt gaataccaag agtacgagct
    26101 gccataccaa ggtgaagctc cataacctga ccgatattca tacgtgatgg caccccaagt
    26161 gggttcaaca tgatgtcgac tggagttccg tctggaaggt aaggcatgtc ttctacagga
    26221 acgatacgag agacaacccc tttgtttccg tgacgtccgg ccattttatc tccgacctta
    26281 atcttacgtt tttgagcgat gtaaacacga accaacatgt taacacctga ttgcaactca
    26341 tctccattta cacgtgtaaa gatcttaaca tcacgaacga caccatcggc accgtgtggt
    26401 acacgaagag aagtatcacg cacttcacga gacttgtctc caaagatagc gtgcaagaga
    26461 cgttcttcag ctgaaagatc tttctcaccc ttaggtgtta ctttacctac aagaatatca
    26521 ccttctttaa cctcagcacc aatacggata atccccattt cgtcaaggtc tttgagggca
    26581 tcttcaccaa cgtttggaat ttcgcgagtg atttcttcag gcccaagctt tgtatcgcgc
    26641 gtttctgatt cgtattcttc aaggtgaaca gatgtgtaga catcgtcctt caccaagcgt
    26701 tcgctcatga taacggcatc ctcgaagttg taaccttccc aagtcatgta ggcaacgatt
    26761 gggttttgtc caagcgccat ttctccattt tccatagaag gtccgtcagc gatgaaatcg
    26821 cctttttcaa cgacatcacc aacttttacg agagtgcgtt ggttgtaagc agtacctgag
    26881 tttgaacgac ggaatttttg gatgtggtaa acatccaatg aaccatcttc acgacgaact
    26941 tctaccttat cagcatctgc gtaagtaact ttaccatcat actgagcaat cacagccgca
    27001 ccagaatcgt gggctgcttg gtattccata ccagtaccaa cgtaaggtgc ctgaggatta
    27061 atcaatggca cagcctgacg ttgcatattg gctcccatga gggcacggtt ggagtcatcg
    27121 ttttccaaga aaggaataca tgctgtcgca acggcaacta cctgttttgg tgaaacgtcc
    27181 atgtagtcaa caatattagc tggatactct tggttgaccc cttggtgacg tcccatgaca
    27241 atcttctcag caaaggttcc atcttcattc agacgagagt tagcctgagc tacagtatat
    27301 tcatcttctt catcagctgt caaccaaaca atttcgttcg tgacaacacc tgtttcacgg
    27361 tcaaccttac ggtatggtgt ttgaacaaaa ccatatttgt tcaagtgtcc gtaagatgac
    27421 aagttattga tcaaaccgat gttaggtcct tcaggtgtct cgattggaca catacgacca
    27481 tagtgagtgt agtgcacgtc acgcacttca tatccggcac ggtcacgagt caaaccacca
    27541 ggtcctaagg ctgacaaacg gcgtttgtga gacaactcag aaagcgggtt gtgttggtcc
    27601 atgaactgtg acaactgtga tgaaccaaag aattctttaa ctgcagctgt tacaggacga
    27661 atattgataa tttgttgtgg tgtcaagact tcattgtcct gaacagacat acgttcacgg
    27721 acattacgtt ccatacgaga aagtcccaaa cgtacttggt tggcaagcaa ttcaccaacc
    27781 gcacggatac gacgatttcc aaggtggtcg atatcatcta cacggccaag tccttcagcc
    27841 aagttgagga agtagctcat ctcagcaagg atatctgcag gagtcaccgt acgaaccttg
    27901 tcatctgggt tagcattacc aatgatcgtt acgacgcgat ctggatcagt tggagcaaca
    27961 accttgaatt tttgaagaac aacaggctca gtcacaacgg ctgcatcgtt tgggatgtag
    28021 acaatcttgt tcaagtcgcc atccaaatgg ctttcaatgc tttcaatcac gctacgagtc
    28081 ataatcgtac cagcttctac caagatttct ccagtttcag ggtctaccaa tggctctgca
    28141 atggtttggt tgagcaaacg tgttttaaca ttgagttttt tattgatttt gtaacgacca
    28201 actgctgcca agtcatagcg acgtgggtca aagaagcgag ccacaagcaa gctacgtgag
    28261 ctttcagccg tcttaggctc acctggacga aggcgttcgt aaatttcttt caaggcttcg
    28321 tctgtacgag agtccattgg attcttgtgg atatcttttt caacagtgtt gcgaaccaat
    28381 tcgctgtcac caaaaatatc aaagatttca tcatcacctg agaaaccaag agcacgaacc
    28441 aaggttgtaa atggaatctt acgagtacgg tcgatacgag tgtaggtgat atcttttgag
    28501 tcgctttcaa gttccaacca agctccacgg ttagggataa cagttgaacc atagcccacc
    28561 ttaccatttt tgtctacttt gtcgttaaag taaacacctg gtgagcggac caactgagaa
    28621 acgataatac gttcaccacc attgatgatg aaagtaccca tttctgtcat gattgggaaa
    28681 tcaccaaaga aaacttcttg ggtcttgatt tcgcctgttt ctttattgat caagcggaag
    28741 gttacaaaaa ttggtgctga gtagctagca tcgtgaatac gagcttcttc tagcgtgtat
    28801 tttggttcct tgatttcata tccaacaaat tccaactcca ttgtgtctat gaagtttgaa
    28861 attggcaata catcttcaaa cacttcctta agaccgtggt ctaggaaagc tttgaatgag
    28921 tcagtttgaa tttcaatcaa atttggtaag tcaagaactt ctttgattct tgaaaaacta
    28981 cgacgggtac gatgtttccc gtattgaacg tcatgtcctg ccaagatgat tctcctttgt
    29041 aaataagttc caagccttgt caatcaggct tttctaatcg tcatatggtt gtaaacccct
    29101 tatcaccgtg tcctcttgac gatttttcag aatctttaag cctctgttac aaatgctcaa
    29161 aatcttgaaa aaaagcacaa aaagagcagc taaatctgac tttttcagaa gatttaactg
    29221 ctgtgagcct tgtctggaca atatttcaga caaaacctac gacaaatgat tacccatatt
    29281 ataccctatt tagctagatt tttcaagggg tttcagtagg tttttggtaa attttttccc
    29341 atagaaaact tggcatcaca ttcgaatcac gctatggtac aaaaaactga aaaaactatt
    29401 gactgaaaat cattttcaag gtataataat aaacgttaag gcggtatagc caagtggtaa
    29461 ggcacggctc tgcaaaagct tgatcgtcgg ttcaaatccg tctaccgcct tctataactt
    29521 gatttatcag gtttcaaatg aacagaaagc ccaatttgaa gggcttttct tattttccct
    29581 cgaataaata cgtataactt taaaaacttt tggagcgagt ttgtggcaga gttctttcca
    29641 tggcataatt cccttttgaa atcaattgaa aaaagcttcg tcacgcctgg tgacaaaagc
    29701 ctctagttta ttctgtttct tcttctattt cgacttctgt gatttggatt tttaccttgg
    29761 taacacgtcc attcttcact ttatcattgg ttaagataaa ctgtttgttt tggctgacca
    29821 attcatagct gagtttctca gtcgttggaa tggttcccac tcctgtcaaa taataaccag
    29881 cgatagtatc aacgtcatca ctttccagtt caacattaaa gtaattattg aaatcattga
    29941 gggtcatagt tccttgaaca atgtaggtat cctcgccaat ctgatgaaca tctattgctg
    30001 ctttgtccgt ttcatcatca atttcaccaa caatttcctc taagaggtct tccaaagtca
    30061 ccaaaccagc cataccaccg tattcatcca gcaagattgc catttgtctt tgggtatttc
    30121 gcagttcttt tagcaagtca tccacaaaaa tagtttcagg tacaaaaagt ggatcttgta
    30181 aaattctctt ccaaacaata ttgtcaaaac cgtccacaaa gcctgcctta aggagactct
    30241 tggtgtgaat gattccaatt acattgtcct tatccccatc ataaaccggg atacgagaat
    30301 aattttgttt taaaatactt tggataatgg cttgactatc atcctgaata tccaccataa
    30361 aggcatccgt tcgaggaacc ataacctctc gtgccatcag ttcatcgagc gaaaagacac
    30421 cttgtagcat ctcaatctca tcagcatcca atgtttcttc actatttgtc agcatatagg
    30481 caatttcatc acgggtcatc ttttcatccg catcatcgaa tgacatagga gtcaaatggc
    30541 tcaagaaatt ggtcgaagca gctaaaagcc aaacaaaagg actgactagt tttccgatcc
    30601 caatgataac cggcgctgta cgaattgcca aggcatcctt tagattaaga gcgattctct
    30661 taggatataa ttccccaaaa acgatggaaa tataggtcaa aaatgccaag gatagaaaag
    30721 ttgccacggc ttgtgctgtt tcgccattcc caagccaaga ggcaatcaca cgtcctagag
    30781 tattagttaa actcgcccct gataagattg taatcagggt gattcctacc tgaatggttg
    30841 ataaaaagtg gttaggattt tctagtacct tcagcaggcg gatgtagcgt ctgtctcctt
    30901 cttccgcctt ttgttcaact cgggcacgat taagagaaac catggccatt tctgtggctg
    30961 agaaaaaggc atttaatacc gtcaagataa acaataaaac aaattgtagc aacaaattct
    31021 gactacttgg gtcttccata gttcttctcc taaaatagta tcttatcctt tattatatca
    31081 caaaatttaa tccaatacat attatttttt tcttagcgta acttccatct ctctcccaaa
    31141 actggaagtt agtctaagac ggatttccac tgatttcacg cgtttttctc atactaaaag
    31201 ctaggttgtg ggaaactgga agttagtttt agaagttact attttttctt agtacctgtt
    31261 ctagccctgc ttaaactagt aaaaagaact cctacatcca taagtgacat aggagtttag
    31321 gcttatcttt tactgagtta cagttacttc tccagttcgg taatccagtt gaagtccctt
    31381 ttgaacattg ggaactagaa cattgaattc caattctcca tccgaagact tggcttcaat
    31441 ctgtgaagct gagggaacta aatcctcgtt tgaagcgtag taaagggtta cacggtaacg
    31501 gacacgcttg ttttggtcca aggctttacg caccttgctt tcatagtagt tttgaccagt
    31561 cgaatactcg gcttgtgcct gatttgccca ggctgtctga acagcaatgt ttttaggatt
    31621 gcttgttgag gcatcaaaac catccaaacc accgattaag gcatagccta acaaatgacc
    31681 tctatcgact gcatgggtat aagagccctt tagattcttg acctgatgcc aacctggagg
    31741 agtccaagaa gttgaaccat tcccagtttc tttacgattc ttgtactgac gagtggcctt
    31801 agacaagaga gcattagcta cggttggaac agtttccttg cccactgtct ttgttttatt
    31861 gtcagcgtag ggcttacttg aaaccttggc atctagattt gttttattac cattgacgat
    31921 aaaagcacct gagccattcc actccagact cccctttatt tgactcttga ctgcgtctgt
    31981 taagacactc tctgccaatg cttgactagg agcttcagac gcttgttttt tctgactcat
    32041 ttttgtctta gcagcctgat ttcctagttc attctgctta atataatagc tccctgcaga
    32101 caaaagcaat aacactagca gtccaatcag tgtctgtctt gtttttttgt tcatatttct
    32161 ccttatcttt ataaaaaggc tggtctccca gcctaatttc ctgtaaattt atgaatcaat
    32221 tcctgccatt ttgccggaga caggatagcc cacggatctt gacccttgcc caagattcca
    32281 tagcctacca ttaaaccgat tcctaaggct agaaggccta aaatcagtac cagaatgact
    32341 aaaagtaaac gcttaattac gtaacctgat ttcttattca tcttcatcac ttgcctcaat
    32401 ccgctgaatc ttagcaccta gctgcgccaa cttctcatgg aaaccgtagt aacctctatc
    32461 caagtgaacc aatttaccga ccacagtttc tccctgtgct accaaacctg tcaaaatcaa
    32521 ggccgcactg gcacgaaggt cagttgaaag aacttctgct ccctgcaaag gctgtccacc
    32581 aacaatacga gctgtatcac ggataatctc agaatgcaag cccatgcggc gcatctcttc
    32641 taggtgttgg aaacgatttt caaaaactgt ctccaccatg gttgattcgc cttttgcaac
    32701 tgtcatcaag gctgtaaatt gagcctgcat atctgttgga aatcctgggt ggggcaaggt
    32761 tttcacatga acagctttta gattttctag ttgagaacga acacgaattc cttcgtcttc
    32821 ttcaattact tcaacaccca tttcaagtaa cttggcaatc aagggacggt tgtgctccca
    32881 gacagcgtct cgaatcaaga catcaccacc agtcatggca gcagctacca taaaggttcc
    32941 tgcttcgata cggtcttgga ctacattgtg agtcgtgcca tgaagtttct caacaccagt
    33001 aatggttata gtctctgtac cagcaccttt gaccttggct cccatttcat taaggagaat
    33061 ggctaagtca acaatctcag gctcacgcgc agcattctca atcactgtca ccccatcagc
    33121 cagagtcgct gccatcatca agttctgcgt tgcaccaaca cttggaaagt ccatatagat
    33181 atgagcgcca tgcaagcgtt ctgccttggc ttcgatgtaa ccagctgtct gactaatctt
    33241 aacccccata gcttccagac ctttcaaatg aagatcaata ggacggctac caatcgtaca
    33301 accacctggc atggatacct tggcatgacc cacacgggca aggattggcc ctaatacaac
    33361 gatggaggcg cgcatcttgc tgacatactt gtaaggggct tcctcagtga tgtcgccagt
    33421 agcatccacc ttgacaagat gagcttcctc atcaaagtca accttggcat tcaaaccacc
    33481 aactacctga ttcataataa agacatccga caaaatcgga acattctgca agacggtctt
    33541 tccttcactt gctagaatag tcgctgccaa caagggtaag actgcatttt ttgctccctc
    33601 gatcgtcacg cttcctacca gacgattatc gccaccttga accacaattt tatccatact
    33661 cgtttccttt actcttgatt tcataataat cctctaagcg cttcttgcca caaatgatac
    33721 aggctaataa agaaagaact caggatgtag cctatgacaa tgctaaaaaa ggctactaat
    33781 aaacgaactt ttcttgtatt atcatctgtc acttttaaaa ccttctccca tctaacaaga
    33841 tcctttaaaa ggtaaaaact cacataaata aagaacatat gactacttag agtgaataat
    33901 aattgaacca tttgactatt ataccatctt ctctgtttgt gcgctagttt ggaaacttca
    33961 ctcaaaaatt agggattgtt tttcaagtaa tcaatcgcat cttgtagggt tttaacgggc
    34021 acgattttca tatccgtctt gattgtttta gccgcttcta gggctgtttg gtagttgttt
    34081 ttcgcgtccg gatgcgcctt ttgttcttct tcgctaacag ggttatcagg agcaaagaaa
    34141 atagcagcac ctgccctagc cgaagctaca accttcttat caatacctcc aatgtctccc
    34201 acattaccat cgcggtcaat ggtacctgta ccggcaacaa tacgaccatt acgaagatct
    34261 gggtgagcta tttgagtata gatagctaga ctaaacatga gaccagcact tggaccgcca
    34321 ataccagctg ttgaaaagct aattgggaca ttgctgatta cctctgtacg gtcaatcaag
    34381 ccgattccaa ttccattttt gccattttcc aaggtgatga tttttccttc tgcagacttg
    34441 gtttgcccat cctcttcata ggtgaccttg acggaatccc ctaatttttg agaactgacg
    34501 taatcaatca agtctttgga actatcaaag gtctgatcat tgactgctgt gaccgtatca
    34561 gagatattga gaatcccttt aaaggttgaa ttatccgtca cattcaaaac ataaactcca
    34621 aagtacttga gttcgatatc cttaccagct gtttttagtc cttgatactt ggccatattt
    34681 tgcgatgttt gcatgtagaa ttgattgatt cgcataaatt caacatcgga agaaccacct
    34741 gtagtctcct gagcactacg aatatctgta aaaggtgtca accaagcata aatcatatga
    34801 gctaaagtgg catgttgaac accaaccgta acgaattgat aggcaccagc ttccttatct
    34861 tctgtgtcat ttactttaag gacttggcga atatcttccg aaccacctgg aacctctata
    34921 taataaggca agggcactac aaatgccaag aaagtcacaa tcaaggccgc aatgacgtat
    34981 aagggccatc taatcttttt tttcatttct tatttcctcc aaaatactct cgggaacata
    35041 gcaggcaata tcctgaccaa acttcaaaag ctctctaacg cctgatgaac tgatatagag
    35101 atgttcaggt cgactatgta aataaatagt ctctatatca gaagacagct gatgattgta
    35161 gtaatcaaaa ctggcttcat attgcaaatc cgacgcattc ctcaaaccac gcactagaca
    35221 agtagcaccc aatctttttg caacatcgac caccaattca tcatgagaag ccacgacttc
    35281 aacattttcc aaatgtccca aagccttttc tagcccccgt ttacgatttt caagagggag
    35341 aaatccttgt ttgtggggat taaaaaaaat acccacacaa agcttatcaa aaagtctgct
    35401 cgcccgttca atgatatcca gatgcccatt tgtcatcgga tcaaatgagc ctgtgaataa
    35461 gccaatctta tctgacatag actgtcacct tactaattcc ataaatcttt tccttccaga
    35521 tacccagaca ggcaatttct tctggaagtt caacggcctt atccgtctcg cacacaacca
    35581 taacatcttc agaaaaaagc tctctctcag ccattttttc aatatctgct acgatttgtt
    35641 ccttggcata gggagggtct aagaaaacga ggtcaaattc cccagatacc tgttccaatg
    35701 ccctctctgc atccatcttg aggagttgaa attttccaac ttccttggtc atctggatat
    35761 tttcagccac gatggtctga gccttacggt ctcgctccac caaaacagca ctggacatgc
    35821 cacgcgatac tgcttcgata gataaaccac cactacctgc ataaaggtcc aagactcgtc
    35881 ccccttcaaa gtagggacca atcatgttaa aaatggctcc cctaacctta tccgaagtag
    35941 gtcttgttgt cttgccttct agtgtcttga ggggacgtcc cccatagatt cctgatacga
    36001 ttttcatact gtttattata ccaaattata gacaaaaaga gaaagaaaac cgaaccttgc
    36061 ggttcgattc tctacaaaat attttcgtaa gtatcgcgga cttcttgagg ccaaacactt
    36121 gtttgcactt ctccgatgtg tctcttgcga agtaggaaca tggccatacg agattgtcca
    36181 attcctccac cgattgtcaa tgggaataga ccattcaaca aagacttgtg ccattccaat
    36241 tccaagcggt cttcatcacc tgtaatttcc acctgacgtc taagagtttc ttcatctaca
    36301 cgaattccca tagaagacaa ctcaaaggct ccacctaaag actcattcca gacaagaata
    36361 tcaccattta gacccttgta gccattctca gactcgcttg tccagtcatc atagtctggt
    36421 gcacgtccat cgtgcggttt accatctggc aactcgccac cgataccaat caaaaagacg
    36481 gctccaaatt ctttacaaat cgcattttca cgttctttcg gtgtcaagtc tgggtagcgt
    36541 tctaccaatt cttctgtatg gataaaggtg atttgttttg gcaagataga ctcgatgtca
    36601 tagcgggctt caacagctag ctcagtcagg cgaatagcct tataaatctt ctcaactgtt
    36661 tcttttagat aaacgatgtt acgcttacca tttgggataa ccttctccca gtcccactgg
    36721 tcaacataaa cagagtgggt tgcatccaag gaatcctcat ctggacgaag ggctttcatg
    36781 tggacaaaga gaccctctcc ttcaccaaag ccaaaacgag ccaaggtgtg gcgtttccat
    36841 ttagcaagtg agtgcaccac ttcataagta gcatcaggga tttggagaac cttgaccgat
    36901 actggatttt ccacaccaga caggttgtcc tgcattccgt caccgacctt actcaagata
    36961 ggaccttgaa cttcgacaac ttctagctta tctttcaaat actgggtaaa agtgtttttg
    37021 acaaaggaaa tttcttcttg ttgatggata aaacttttct tcatagacaa ctcctcaaaa
    37081 atttaataaa cgtattatac acctatttcc aagaaaagaa aagagaaaat ttaaaaaaat
    37141 cagtgtcact caaaacactg atttcataga ccttttagtc attgcgacca aagatacgta
    37201 gaatacttag gaaaagattg ataaaatcaa gatagatgct gagagccatt gacaccaccc
    37261 agcctgtcgc tacacgacct tgtgattgtt cataggcgag gcgaatcttt tggttatccc
    37321 aagcaatcaa ccctgaaaaa accaaaacca tggctacgct aatcatataa tcaaagaagc
    37381 cactagccaa gaaaatattg actaccatag caatcagtaa accaatgaga gctgccatca
    37441 ttgctcgacc aatcccactc aagtctttct tggtaaagat accaactgcc gccatgacaa
    37501 agaagagaag ggcgctcgat acaaaggcag ataaaactgt acccggagta tagaaagcca
    37561 ccacaaaact aagggtaaag ccgtttaaaa cggagtaaag taaaaatact ggaagagcag
    37621 ctggactatt tcttgaagcc atgctactgg caacgaaaac caaagccaac tccgcaaaag
    37681 tagcaatggt caaccagaga cgcccctgca tcaaaaagta aaccaactga gactgaaaga
    37741 ccgtcaacat aaggcctgat accaaagcag atagtccgat tcccagacca acaaaggcat
    37801 aaaccttagc gtaaaattga ttgagacctg cacggtcatg tataatagtg tgattcatcc
    37861 atttctcctt ttctgtgaac atctttcctt gattataaca aaaaaagtta aaattagctt
    37921 aaatggaaga ttaaaatacc ggctgcaacc gcaacattca aactctcggc ctgccccttc
    37981 atgctaatat ggaccaactg gtctgcactt tcagccataa ggggactaat tccttgaccc
    38041 tcatttccca taactagtac aaaattttct atagaaggca gttctctgta atcaacagaa
    38101 tctttagata gggttgttgc tagcactggg atagctacct ttttagtttc gtcaagaagc
    38161 gcttgactag tcatccggta aatgggcaga tggaaatgac taccttgcat ggaacgtagg
    38221 gttttgagac tgtagatgtc tgccgactta tctgaaacaa tcactcctgt aaaacctgct
    38281 gcatccgcag ttcgaatgat agttcctaca ttaccaggat cttgcacatc ttccaaaaac
    38341 aagaacttgc cctgactcaa atcagcttgt cctacttctt ctctttgaac cacggcaaca
    38401 attccctgtg gagtctgaga atccgccaaa tctagcaaaa tatcctctga cacccagaca
    38461 gtttgcgaaa aagtagctaa ctgatctcga taattttcta gggtaaagat tttctcaatc
    38521 gtcactccag cttgaacagc ttcttcaaac aagtgccagc cttcaatcaa ataggctgac
    38581 ttgcggtatt ttttttggtg taatttcttg gtatttttta ccacagaatt ggcttttgag
    38641 gttataatag tcatagaaat attataacac aatcaaaggg gtttggtatg caaaaggtta
    38701 gaatgattgc ccaaggtagg gtacagggag tcggctttcg ttggggtgtt tacagcttgg
    38761 cacttgaaat tggtggcatc acaggtcgag tatggaataa cgacgatggc acagtggaaa
    38821 tcttagccca agcagactca tctgctatca tggcaaaatt tatccaagaa atccgaaaag
    38881 gaccgacacc tttttcaaaa gtaagctact tagatgtcaa actaagcaac tttcctccct
    38941 actctgactt taaaatcgca aattaggtct ccagaactat tgtatatttt gtaaaaaaac
    39001 agtagaatag aaaggtataa tttttaaaga aggaataaaa acagtgaaat ctattaaacg
    39061 ttttgcattc tcggctatgg gagtggctat gttgcttgtc ttgactggct gtgtcaatgt
    39121 cgataaaacc acaggtcagc caacaggatt tatttggaat acgatcggag cgcctatggc
    39181 tgaagccatc aagtacttcg ctactgataa aggtctaggc tttggtgtcg ctatcattat
    39241 cgtaaccatt atcgtacgct tgattatctt accacttggt atctaccaat catggaaggc
    39301 aacgcttcac tctgaaaaga tgaacgctct caagcatgtc cttgagccac accaaacacg
    39361 tctcaaagaa gcaactactc aagaagaaaa actcgaagcc caacaagccc tctttgccgc
    39421 tcaaaaagag cacggcatca gcatgtttgg tggtgtagga tgtttcccta tcctccttca
    39481 aatgcctttc ttctctgcta tctactttgc tgcccaacat actgaagggg ttgctcaagc
    39541 aagctaccta ggcattcctc taggttctcc aagtatgatt ttggttgcct gtgctggtgt
    39601 cctttactat cttcaatcgc tcctttcact tcacggagta gaagatgaaa tgcaaagaga
    39661 acaaatcaag aaaatgattt acatgagccc actcatgatc gtcgtcttct ccctcttctc
    39721 accagctagt gtcacacttt actgggttgt cggtggtttc atgatgattc tccaacagtt
    39781 tatcgtcaac tatatcgttc gtccaaaact tcgcaaaaaa gtccgtgaag aactagccaa
    39841 gaacccacca aaagcaagtg ctttctctaa accaagtgga cgaaaagacg ttacccctga
    39901 acaaccaact gctatcacaa gcaagaaaaa acacaaaaat cgcaacgctg gaaaacaacg
    39961 ttcgagataa gaagaaaaag gcttagctga tttgctaagt ctttttgcaa atcaaaagcc
    40021 cgatgtttcc atcaggcttc ttttctatcc atgtacacgt ttcatataat cttgataact
    40081 ttcggtatcc atgagttttt tagcgttctt gacgcgatct gctgttggtg gtttgactcc
    40141 ttcgagggaa tatggaattc caagttcacg ccacttgaac tcacccatgg tgtgataagg
    40201 tagaatttca aacttatcaa catttttgag ggtcttgacg aacttaccaa gttcaatcaa
    40261 gtcatcatct ctgtctgtca atcctggaac tagcacgtgg cgaatccaga caggttttcc
    40321 aatatctgat agatactggg cacaagccaa gatattttta ttagtttgtc tagtgacaat
    40381 cttgtgctgt tcttcgttga tttccttgat atccaaaaga accaagtcag tgacagccat
    40441 gagtttgtca aacttctcaa ggtaacgtgg tttattacgg aaaggaagag cacaggtatc
    40501 caaggtacag tggattcctt gttccttagc cttggtgaag agagcaatca ggaaatcaat
    40561 ctgcaagaga gcttctcctc cactgactgt aatcccaccc ttatttcccc agaaaccacg
    40621 gtagcgcaag gcctctgtca agacatcatc taccgtccgt tcacgtgact tattggactc
    40681 catagcccaa gtgtctgggt tgtggcaata ctggcaacgc atgtgacagc cctgcaaaaa
    40741 gacaataaag cgaataccag gcccatctac tgacccaaag ctttctgtcg aatgcaccat
    40801 tcctgtcact tgtccataat caattgtttc ttcagacata tcgttacctt ccttgaaaac
    40861 gttttatagt tttattatat cacgacttga aggaaaaaca agatttttgc ctatttttta
    40921 gaaagcaatc tgtttttcaa tttcattttc aatctattat cagattattc ttcaaaatcg
    40981 aagccatata aggttgcaaa atagtcctca gggcgctctg cacggcggat ttgacgggct
    41041 ttaccttctt cggtatagag gatttccgca gaacgtaatt tggcattata ctggtagccc
    41101 attgaaaatc cgtgggcacc tgtatcatga attaccagca aatcaccgat ttctgtatga
    41161 ggcagttcgc gattgactgc aaatttatca ttgttttcac agagtgaacc aaccacatct
    41221 accgcttcag ctggtccatc tggatgggtc acgttgctaa tatgatggta agctccgtac
    41281 atagctggac gcatgaggtt gactgctgag gcatccacac ctagataggt acggtaggtt
    41341 tccttcttat gagtcactct tgtgactaga gcaccgtgag gtgccagcat aaaacgaccc
    41401 aattcggtga aaatcttgac ctgaccaaga cctgctgacg taagaacttc ttcatacacc
    41461 ttacgaactc cctcaccaat caaggcgata tcgttcggct cctggtctgg acgataatta
    41521 acaccaatac cgccagaaag attgataaag tctagccaaa tgcccaactt ttccttgatt
    41581 tcaacagcca gttcaaagag ctgacgagcc aactctggat aatagagatg ggtcacggta
    41641 ttggacgcta ggaaggagtg aatcccaaaa gtcttggctc ctttttcctt caagatagca
    41701 aaggcttcaa agagctggtc cttggtcatg ccaaacttag cctccccagg attgtccata
    41761 atgtctgtcc ccagttcaaa aacgcctcca ggattataac gacaagagat gatttctgga
    41821 atgcctgcta ctctctccag atgttcaata tcttcaaagg catccaagtt aatggtcgca
    41881 cccaattcac gtgcataggc gtattccttg tctggcgtgt tgttggaaga gaacataatc
    41941 tcagaaccca gaaagtccag tttatggctc atcaaaagct ctacataact agagcagtcc
    42001 acaccacaac cttcttcttg gagaattttc aaaatagctg gagttggagt agccttaact
    42061 gcaaaatatt ccttaaagcc cttgttccac gaaaaagctt ggttgacggc tcttgccttc
    42121 tcacgaatcc ccttctcatc atacaagtga aagggagtcg ggaactcggc aacaatcgct
    42181 tctaactctt ctctattgat aaatggtgtt ttcataagct tccttctatt ctgtttgcaa
    42241 agaaaggctg ggacaatcgt tccaaccttt agttctatct cttatttatc ttcgtcaaag
    42301 atattgccaa cctcaacatc gatggcttgg ttcttgacat caatattggt taccttcaag
    42361 agtgacttgt agtcaaactg cttttcacgt tcttcttggg cattgtccgc aaagaccgct
    42421 acacctgcca gttctgagtc gaactcgcgc aagagactaa tcataccatt gaccgttccg
    42481 ccacctttca agaagtcatc cacaatcaag acacggctgc ctgccttaag actacgtttt
    42541 gaaaggaaca ttttctcgat acggtcacca cttgaacctg aaacatagtt gacgctaaca
    42601 gttgaacctt cggtaatttt caggtcacgg cgcacaatga caaaagagac attgaggaca
    42661 ttggcaactg catttgcaag tggcacaccc ttagttgcta cggtcataac cgcgtcaatt
    42721 ttttggtcca taaagctttt ggcaataata cgaccaatat ttttcaagat ggctggtgtg
    42781 ctaagcaaat cagacagata gatataacca cctggcaaga tacggtcact ttctgacaac
    42841 ttggtacgca agtcttcaac catttcctta gcatcctgac tcgaaataga cggtgtgaag
    42901 atgacacctc cgccagcccc agtcactgtc tggatatgac cgatttcaat ttcctcaaag
    42961 gcgcgtttga taatgacgat atcttctgag atggatgatt tagcagactc atacttttca
    43021 gcaaaagtat tgagactagt tagtttataa ggattattaa tcaaatagtt ggaaatgaca
    43081 accatccgat cacttcttct taatttcatt tctatttcct attccatttt tattcaaaaa
    43141 atcaaaaagc aaactagaaa gctggtcgct ggtggttcaa aacactgttt tgagattgtc
    43201 aatagaactg acaaaccctg taatatacct gcatatatac atacgacaag gcgatactac
    43261 cctagtttga agagattttc gaagagtatt catttttgtc ttttacttat tataccatat
    43321 tcacataaaa aaacgaacat tcttatccta aaaaatgctc atttttctta aattatcaat
    43381 ctaaatctgg tttatagaag gaacgattat ccatagcgaa gattttattg gtcatctctc
    43441 ctttatccac caaagccaga gctgttgaca tcatcatcat gcttgcatcc agattgtcaa
    43501 tcatatggat aatctctgcc tccataatac gtggacggac tggacttcca tattcaagca
    43561 agccgtggtg actgaggatg acatgacgaa gcaaaacgac ttcttccttg gtatcatcga
    43621 tgccgagttc cataactgtc ttggtaattt cgctatcaat gagagcgata tgtccaagaa
    43681 gattacctcg cactgtgtac tctgtctggt ctggccccgt caactcgatg accttagcca
    43741 agtcatgcag cataatcccc gcatagagca ggctcttatt gagctgagga taaacttcgc
    43801 taatagcgtc tgccaaacgc accatggtcg ccgtatgata ggccaagccc gtttcaaagg
    43861 catggtggtt ggtcttggca gctggatagg agtagaattc cttatcatac ttggtgtaga
    43921 gatttcggac aatccgttgc cagacaggat tttcaatttt gaaaatcatt tgcgacatgt
    43981 agtcacgaat ttccttgaca tcaactggtg acttgacctt gaaatcagct gggtcattgg
    44041 gttcaccagc ttgaggcagg cggagagtaa tttgattgac ttgaggggta ttgttataaa
    44101 cttctcggcg tcctttcatg tgggcaacct tacctgcggt aaaggcctca atgttatgag
    44161 gttgggcatc ccagagcttc ccatcaatct cgccactatc atcttggaag gtaaaggcta
    44221 ggtagttttt cccagctcga gtttgcctca ggtcagctga tttgattagg taaaagcctt
    44281 caaataactc atcttttttc atgtgactaa tcttcatatt cttcctcatt ttcttgaaaa
    44341 tggagtagat caagcgcagg ctcaccttct gacaactcaa tgtgacggag cgtccgctcg
    44401 atagctatgg tacgacggtt taataattca tcaatattgc cagaggcatg ttggagatgt
    44461 ttttgtgcct tgaccagaat accaccaaac ttgccaaact cggtcttgac actggcaaga
    44521 gtcttgctga tatggtcggc actcttttgg atattaaggg tcttgaaacc aactgatagg
    44581 gagttaagaa gggctgatag ggtacttggt cctgcaacaa taatctgttc ttcccgtctc
    44641 aaatcatcaa agaagaccgg attgcggacg atttctgagt agagaccttc tgtcggaaca
    44701 aacaaaactc caaaattggt cgtccgaggt ggtgctatgt acttgttcct aatatcccta
    44761 gcaaagcgct tgacgcttgc taggagtgac ttacgacagc gttcaatctc atccttgtca
    44821 cctgtctcat aggctgcttc caagcggtaa taatctgcca gtggaaactt agagtcaatt
    44881 ggcagataga cgtattcttg gtcgccttgt ccgggtaact tgatggcata ctccactcgt
    44941 tcactagagt tttcaaccgt tgcgtattct cgttcgtact gggcaggtgt catgatgtct
    45001 tcaataattt gccccagttg caattctccc agaatccctc gcgtcttggt tccagagaga
    45061 accttgttaa gagctccgac atcacgggca actgtctgca tttctccaag gccacgattg
    45121 acagactcca gttgtttaga aactgtctca aaggaagcct gtaagcgtgt ctgcaaggtc
    45181 ttttctagtt tttcctcgac cgtctggcgc atttgttcca aacgttgctc atttgattcc
    45241 tgcaaggctt ggagacgttg gtctgtcttg tctctagttt ggaggagatt atctgtcatt
    45301 tcttgacgga cttgggtcag accttggtgc aattcaatcc gcacttcttg caaacggtcg
    45361 ctgacaacca cttccaaatc tttttggtct aactggctgg cttgtctggc ttggtcaaag
    45421 cggtaatcca actggtctga caaatgatct gcctgatcct ccaagctctt acttaagtgt
    45481 ttctcctgcc tatcctgcct ttgccaaatc agaaagagac cagctagatt ggcaattaat
    45541 aatagaataa gtaaactttc catcctacct cctgtccttg ctatgcagta cgaccacata
    45601 accatctggg caagttaccg acacttccct atctatatat tcgttagaag cgtacacttt
    45661 tttaaagaaa aaattttcct ctgtcaactc atacttggct ccaagaatag tcagctggct
    45721 atcccgaact ggcataaagg ctagatagtc gtagtctgaa cgaggttcta gctgactgat
    45781 tccttctgga caataagtaa tcaagttttg cccatcctca atttctattt gatgcatata
    45841 gggtgccaac ttaggattgc taggcagaaa gacattggcc aacatatggt caatacggcc
    45901 acccaaggca ccgaaaatag tgacctgagc ctgaggattt tgttcaaaga tggttaagag
    45961 agccaattcc agatctgtat catccttttc tggtcgtgct tggacaaaat actgggcacc
    46021 tttttgaatc acctgtcgct cttcttccgt cacagaatca aaatctccga ctgctagagc
    46081 aagaggtaag tcttcttcca agacccagag cgagcctcga tccaccccaa caaaagcatc
    46141 aaaatctgtc cgataatgac cgcggtttcc gcctgcaaaa actgcaaccc tagtccagtt
    46201 gttttctgag agtttgtact cgctcattga cttctccctt aaagacatag gaacctgcta
    46261 caaaaacagt cgcaccggct tctttggctt gagcaatagt ttggtcatca atcccaccat
    46321 ccacttcgat ttcaaagttc aaaccttttt cctcacgaag agcaaccaac tcacggacct
    46381 tatccatggt ttctggcaga aaggcttgcc caccaaaacc tggattaacc gtcatgacta
    46441 aaacttggtc aactagatga aggacgtgct tgatggcttc aactgatgtg ccaggattga
    46501 taacgactga aggcttaact ccgagtgaac gaattttttg gagggcgcca tgaatatgag
    46561 gcgttgcttc tacatggata ctgatgatgt ctgcacctgc acgcgcaaaa tcttccagat
    46621 gatgctcagg gtttgacacc atcaagtggc aatcgaaaac catcttacta tgaggacgaa
    46681 ggctctcgac cacacctgca ccaaaactga tttgcggtac aaaatgactg tccatgatat
    46741 cgatatgggc atattctgcc ccagttgctt ctagacgttt gatttcacgt tcaaagttgg
    46801 cataatctgc tgccagaatt gacggagcaa tcttgtattg agacataggt ttctccttat
    46861 tttggaattt ttttgctgac ttttttatag gtttctctac gattttcaat ttcactaagg
    46921 aattgcaggt aattgtcaaa acggaaggtt gcaataacac cctcttcaac agctggtttg
    46981 acggcacaag acggctcatg ggtatgggta caagtacgga acttacaatc tcggctaaca
    47041 gtagcaatct ctgggaaagc ctgattgagg tcttcagccc ttgatacttc atagtccaag
    47101 gatgaaaatc ctggtgtatc tgcgatttta cccccgttga gattgtaaaa actaacagct
    47161 cgagtggtat ggcgaccgcg acctagactg tctgaaattt ctcccgtttc aagattgagg
    47221 tctggtgcga ttttattgag aagagttgac ttcccaacac ctgtctgccc cataaagacc
    47281 gtaaccttgc ctgttaacaa agacaggagt tcctctttac tggtcacaaa gtcatagccg
    47341 atgtcaccat aggtctgctg gtaaaaatcc agttctcccc tatcttccaa caaatccatt
    47401 ttggaaatat agacaatggg atggatgccc ttgtgctcca aaagaaccaa gaaacgatcc
    47461 agcaaattgc tgttaaaatc aggttccttg acggacatga ttactacagc ttgatcgata
    47521 ttgacaatag gcggacgaac cagactgttt ttccgttcgt gaattttgag gatatagcct
    47581 tctgaatttt cctcggcaga gaaatctacc cagtccccaa cataaggggt atggcctttt
    47641 ttacggaaat tcccacgcgc gcgtgtttga taaacctggc catcactctc cacatagtag
    47701 aaacctgcca aggctttaat gatttgtccc tgcatcttag agtccttgcc ctttaagtgc
    47761 gtctgctaga ccggcaaatt ctgccaagct gagagcttcc ccacgcacac ttggtgacaa
    47821 gcctgcctgg tccaaagcct tggtcagctt gtccttgacc tcttcagtct taccaaagta
    47881 acctgtcaag ttattccaca aggtcttgcg gcgatgggta aaactagcct tggaaacctt
    47941 aaagaaaaag ttctcatctt ctactgctac ggctggctct ggacgacgca ccattttcaa
    48001 gatggctgaa tccacatttg gcgctggcac aaagaccgta cgaggcacga taaaggcaac
    48061 cttggctgtc atgtaatact gcacggcgat agacaagcta ccgtaagcct tggtgttagg
    48121 ctgggctgaa atgcggtccg ctacttcttt ctgcatcatg accacaaact cacaaaaagg
    48181 aatgccactc tcaatcaagt gcatgagaat aggcgtcgtg atgtagtaag gcaaattagc
    48241 cactaccttg attggcaggt caggattttt aaaattctgg atatgttgcg ccaaatcaac
    48301 cttgagaata tcttcgttaa ctacggtcac attatcaaaa tcacgcaggg tatctgccaa
    48361 aattggcacc aaacggtggt caatctcaaa agccatgact tgggctgcac gctcagccaa
    48421 aaattctgtc aaggcaccaa tacctggccc gatttcgatg acattgacct gatcatcaat
    48481 ttcagccgta tccacaattt tttgaaggat attggtatcc gtcaaaaaat tttgcccaaa
    48541 ggacttttta aaggtaaaac cgtgacgctc cagcactgcc ttggtcacgc tataatctgc
    48601 aattctcatc tattctcttt tctattatct gttactacta ttgtaacaca ttccccttgt
    48661 attttgggaa tgaaaatcat accaaaaaac tatctttcct catgaagaaa gatagtcttg
    48721 gaaatcttta aaagtggcct tagcagttct ctcgaaacat gcgttcaaaa aaatcagctt
    48781 cttgataact tcgattttca ggtagggtca aatccacatc ctcctccaca tcatccactg
    48841 tcagttcaac catctgaggt aaatttttca aacgataatg cttttgcctt tgcccttcaa
    48901 tactagcaaa atcaagcaaa tagccatgca ctcggatttg aaccaaaagg agatgattgg
    48961 tcatattttc catgatgagg atatcttcta aaccacctct ggcactagga taatcagata
    49021 ccctgcgaat acggattttt tcacacatga gcaagtttcc tcatatcaat gatttcatca
    49081 gccttattcc agactagggg attatgggtc gcaatgatga taattcgatt ttcatctttc
    49141 aaatccacca agagattcat aacctcttct gaattttcag gatcaagagc tgctgttggt
    49201 tcatctgcca aaatcaaggg tggatttttc aaaatagtct tagcaagggc aactcgttgg
    49261 gcctctcccc cagataaagt atagattttt tgttctaaat ccaaataccc tagattaact
    49321 ttttctaaag cccccacttg cctttccaaa cgttctactt ttgagatttt ctgaccaaca
    49381 aaacccaaat ccaaattttc tttgattgat tggttttcta agaggccgaa attttgaaag
    49441 agatagccca tctggtctcg aaaatactca cgagtgggaa tggtttttaa atctttcccc
    49501 tgatagagaa cccttccacc atctatcttt tctagctttc ccaagatatt cagcagcgtc
    49561 gtctttccgc ttccactctt tccgattaag gcataaacct tgcccttctc cagcttgaga
    49621 ttcaaaccag agaaaatcgc gcggtcatta aatttctttt ccaatccttg aatatcaatc
    49681 atcttatttt cctttcaata ctgccatgct accagcttct tcttttttgt cctgccttac
    49741 taaaatcaag agggcgttaa gcgtaaacaa agctacaact agagcgctaa tcaaaccatc
    49801 tcttgtcaaa atactagata ggactaggcc aagcaagaga actcctcctt gcgccagtaa
    49861 atacttgcca tgaagctcat agattgtcat accagcaaga cgtttaatca taagttcccg
    49921 tctgaactgc tcaaaataga gaagattcat ggaatcaaat aacaagatag ccgtagacag
    49981 ggtcaaaatc gtcccaataa ggagagagta aaactccacc cgtttgtcat ttagtacctt
    50041 ggcaaaaaat agctggcttt ttaccaagta agaaaccttg tgatacagac ctttctcttt
    50101 tagagctgtg atgctgtctc catatcgatc tagtttcaag gcactattag ccgtagttcc
    50161 ccacaacatc cctgcaacag gtcttgttcc agtcgcttgc ggcgttagaa ctacaataat
    50221 cggatctttt aggtactggc gtgttgtctt gtacccatca ttatagagga aacgttcctg
    50281 tcctgtttct gtaaaagcta gccttacctg tgggaggtag tgtttctgac tcgtcacttc
    50341 tacactttca gatgaaaagt tttgcaggta atctgtaaac aatccttggt agtagacaga
    50401 ctgctctcgc aagctctcag gcaagatcag cccaaactct ccctcagaca agttttgcat
    50461 cttgtccata aactctgaag aaacggtaat cttttcttct atcagatagc gtggtgagac
    50521 atagataaca ttccctgacg gtgtgtagtc actgagacga ttgccatcta ggtccacttc
    50581 tgctccatct gagaaattgt caacattgct cataatataa aaagagtctg tattggctaa
    50641 ccgttcttca gtaaatgtct gccactcacg attatcctta cgcgttcctt cttcatcggc
    50701 aaatgcacta gaccaaccaa aggatagacg gtaacggtct gaggactggc tccatttatt
    50761 gctagctctc tccatttcct gcatttcacg gtagtggggt aggagagctg tcgcactcga
    50821 tccgaccacc aatacagcta agagttgccc caccatcatc aatgtcatta tacgtttgag
    50881 agggagtttc cctttcaata gatccaccag actattttcc tgtaaaccaa gtagatagac
    50941 gacacttagt aaggtagaaa tccctgccag ggtcaatcca taaagtagaa gagcaatgat
    51001 gaccagttgc accgttgcca taaacaaggc accttgatac cagagaatcc ccaatcccaa
    51061 aagactggat accagcactg agcagataag ctgtctcaca tcttctaaca ctggtctgag
    51121 agcaactcca aacaagctct caccagctat taagcgaatc cctgcctgac gaagggattt
    51181 gatccgataa atcagggtca gactcataaa ggtcagcaga aaaatagcta aactcagtag
    51241 caccataggg gtggccgtca atagtaagac tatcgaaaat ggatcttctc cattcgaaac
    51301 aaagccttga taaccaagct ctttcaaggt ggtctgtaag ctcactccat ccaaacttcc
    51361 tgatacaatc aagtaagacc ctaataaatc actcgtttct gcactctcct tggaggaaat
    51421 ggtcagacct tctggaagct ttccctcacc ataagtggca taggtaaagc gtgtttctcc
    51481 agcttcattt ggctcaacga ttcgacgagc aatgagacta ttgtgctcta ccgccaagtg
    51541 actcaaagcc tctgtcacct cttcgcgact agctactggt tgatttatca tcattcctgt
    51601 cacatcaaca gaaggatagt taccaaataa aatctcttct cgatggtcaa cggaagttat
    51661 caccatataa agcgatacta ataccattga aatcaaaata aataaacgtt tcatcatttc
    51721 ctccaaaaag ttacttggtc acttagtgag aaggtgacca agtaaagcta aacaataggg
    51781 ctataccatt ctaaacatta tagtagaatg caactttctc tccccaagaa gtacgaatcc
    51841 acgcacgaga agtccctcca gcaccagcat atcccttgtc agatgaacca gtttttctgc
    51901 taacaactgt tgaactatgg tattttgaag ggtgatagta gtttgagtaa gcaccaccgt
    51961 tacctgaacc ataagtccaa acaccacctt ctgggtattg aacggctgca gaggcaactg
    52021 atacacctcc acctaatgtt gctgcaatgc tcgctacaag agctaacttt ttaactgttt
    52081 gtttcatatt gatactcctc tatttttgat tacaagattg ttgagttact tgctcctctt
    52141 tccattatca acgttgatac tattatatta ccaaatgata ttctaaaatt atttgttttt
    52201 ctctaaattg tcaaaatagc accctgaaat gaacttttat agtcattata ctccatcttt
    52261 atcacactat caaggacatc aatgtcctta aaatctaact atttcatatt atttttagct
    52321 tatatctaaa aaaacagttc taaagacgaa ctttagaact gttttgatac gaggacaagg
    52381 acatttttgt cactgattca ctatgtttat aaatattttt tgacatcctc ttgccattcc
    52441 tctgtcaatt tctttactag aaatccatct ccaattagct tcgcaaatgt tttagaagac
    52501 tgataaaatg attcagctaa actaaaatct ctttctactc ttaatgcttg cttccacaaa
    52561 aacataaata caagaggttt cttttgataa tcttgagttt tatccataat ttcttgtaaa
    52621 cacgatagat aatcattaaa acaatcagtt actcctacct tttcaagaca acacattcct
    52681 gaaataagag tatctctaat tataaagtaa ttctctattt gagttacctt cttctgttcc
    52741 aaaagaaaga gcattagctt ttcgatttga tttataaatt tggcaagatc ttttctaatg
    52801 agcatttgat aaaaaaacaa acgaatcaac aacatatcat ttattgaata agcttctttt
    52861 tctataatct gaggcatatg ttcctcaagt attaactctg catattcagg ccttctagtt
    52921 ctagaagtat ccaaacacgc ctgcaatact tcacatgcta attgttcttc tttaggaaga
    52981 ttatcaaagt atgttttata aatctcttcc aaacacgctt ccttcttatc gtactcctct
    53041 tctttaccat agattggttc acgtaaaatc tggtatttca attctaaata agcagaagga
    53101 agagctgaaa aatccggcat aaggctataa actggaactc ctagccggcg agcaatatag
    53161 gctaacttgg gcaaactcgg ttgcgaagct ccactttcaa ttcgcgacag ttgacgaact
    53221 gtcagttctt gctcatctcc acaaaaatct ggacgactaa ttcctttttc tatccgaatc
    53281 tctttaattt tttgaccaat taacatcaga cgcctcctct tctacctgct tcgaaaaata
    53341 ctgtgaaact taaaaaattg taacggctac atctttccta ctcataagat ttcatagctt
    53401 cttccacttc tgccaaagta accccaaaca actctaggcg tttgaggagt tgcttgccgt
    53461 tggaatagcc gattcggaga gtctctccga gatattctct acgcttacgg ctgtctgccc
    53521 ctgctagaaa accaaggcga atcaagtcgc tacgactaat gtcaaactga ctctcatgtt
    53581 caaattgttc tgtcacctga gctagagccg ttttcaggtc ttcatagctg gcatgctcaa
    53641 ttcccagaga acgccccttg gtcttggact tgggaacagc ttcatctcgc ttgagaaagg
    53701 catgctgaac tgttggaatg gccgtcataa tcatgcgccg aatccgctcc ccattaaaat
    53761 ctgggtctgt aaagacaatg actccatgac gttggtgtag acgctgaatt cgctctatat
    53821 cctgatcatt gatggcagaa cctcgtgtct cataggtctc cacatcgaaa taacgcttga
    53881 gattgaccgt atcatcgcga ccttcaacca cgataacttg agaaattttc tctttcatta
    53941 cttgctgtcc aatccaaaaa ttcgttctgc atttgcagtc gttgctaccg ccagctcttc
    54001 tgtcgtcata ccacgcaagt cagcgataaa gtcgaccaca tagcgagtat aggctgtttt
    54061 attttcacga ccacgcttgg gtacaggtgc taagtaaggc gcatctgttt ccaccaaaat
    54121 cttgtccaaa ggtaactctt tagctgcttc ttggaggtca gttgccttct tgaaagtcac
    54181 cactcctgag aaggaaatgg tcataccaag atccacaaac ttctctgccc actcaagcgt
    54241 ccctgaaaat gaatgcatga taccaccacg aggaccaacg ccctcactct tgataatctc
    54301 ataggtatct tccagcgcat cacgggtatg gacaacaaaa ggcaaatcca agtccttaga
    54361 tagctgaatc tgacgacgaa aaacctgctc ctgcacctct ttgggcgctg tcatccaatg
    54421 gtagtctaag ccaatttcac ctagagccac aaccttggga tgttttaact tatccaacaa
    54481 gtaagcctca acttcctctg tataagtacc agcttctgta ggatgccaac caatagtcgc
    54541 atagagctgc tcatactcat ctaccaactc caaggcacgc tcaatcgtcg gtttatcaaa
    54601 accaacaata ttcatctgta tcacacccat ctcagcagcc aaggcaattt cttctgcctc
    54661 acgacctgca aattcttcta cattcaagtg tgtatgtgta tcaaaaatca tctcttctaa
    54721 cctcgttttc tatcttctat tataccaaaa aagaggagga gcacctaatt tttcggtttc
    54781 ccctcctctc ttcaatagag agctattctg ctatcttttc tatccgatat tgcccatctc
    54841 ctattccaca gttagagaca gaagagattg gctacattga tagaatattc ctattcagct
    54901 aaagtatgtg attatcttgg gttctcactt ttctcaccca tcactaggat tgatgacttc
    54961 tcaaaatccc ccttataatc taactttaag tagagaatag aattttctag ctgttctatt
    55021 ttctacgtct agtctttctt cctagcaaag caaaaccact tgttgccacc actagaccaa
    55081 gactagcaag tgctgcactt gatgctgaac ctgtgttagg taattgtttg ccagcaggtg
    55141 actggtaggt aacatcttgc attgttcctg cagttgcttg cggtgcactt gttgtcttag
    55201 gagcagcatt aggagccact agtctcttag gaactgtaac catggcaatg gcttgcactc
    55261 caatcgtttc tgcttccttc acatcttcca tagttttcgc attttcaatc tctttgagag
    55321 ctgcttgttt ttctgcttcc actcttgcta aaagttctgc tttttcttta tcagaaagcg
    55381 gtgcgccttt gatttcatcc tgcttgtcct tggctgcttt ttcaatggca tttttagctg
    55441 attctttttc agtagctaat tgcttagaag cttgtgattg agctgagttt tgtgaacctg
    55501 tgtgagctga tccacccgcc tggctaccac cgcctgcatt cgcattagca tctgagcttc
    55561 cagtattgcc tcccttatct ccacctggtg tattttctag cttatactct ggtgtagctt
    55621 cttgagttac agattcacct ttcgcagatt gttgaactgt atcttttcct agaatcgtca
    55681 ctactgaacc atctgggaat gtgattgttg ctgtaccatc tccagctaca ttgattgtcg
    55741 ctccgtctaa tgctgaacca tttgcttgta aaatagcaac cttaactttt tcttcatctg
    55801 ttaaatgagt tatatctttt acatctactc tttgagcagg tgctttaaca gttgattttt
    55861 cagcagtcgg tttagtgcta tcttgtgctt ttggatcttg tgctaccaat tgatttcctg
    55921 gaattgtaat agctgaacca tctttaaaga cgattgtcgc tgtgccatct ccagctactt
    55981 caactttata gtaaaatgaa ataataacag gacaaatcga tcaggacagt caaatcgatt
    56041 tctaacaatg ttttagaaat agaggtgtac tattctagtt tcaatctact ataacatcgc
    56101 ttccgaatcc atttgcatct actgaacttt tttacaaaaa taaaaatcag tagactcgag
    56161 ttcctactga tttttgatag aattcgtttg gattatgcag ccaaaacttt gcgtccttta
    56221 cgacgacgag ctgccaatac gcgacgacca tttttagttg acatacggtt acggaatccg
    56281 tgtttgcgcg cacgacgaag tttacttggt tgataagtac gtttcacgat gaatacctcc
    56341 tcatagattt tgtattcgtt tagccggcta taaagtgatc agttactaaa catactttac
    56401 tattctatct gattctttca cttttgtcaa tagctctagg caaatgtttc cagctttttc
    56461 gaatgcaagc cctatctacg atactgtttc aagaaacgag tcatcttttc ttggatttgg
    56521 gctaactcat caacacgagg aaggtaaacg atacggaagt ggtctggttc ctgccagtta
    56581 aagcctcgac catgaaccaa gagaaccttt tcctgcttca agaaatcaag gacaaactgc
    56641 tcatcatcat cgatacggta catattgcgg tcgatttttg ggaagatata gagccccgcc
    56701 ttgggtttaa cggcagacaa acctggaata tcttgaatgg cattatagat gaaatttctt
    56761 tgctcgtaga ttcgtccacc aggaagaagc aattcatcga ctgattggtg accccccaag
    56821 gaagtttgta cgacttgttg ggccaaaacg ttagagcaaa ggcgcatatt ggacagcata
    56881 ttgagccctt cgatatagcc cttaacatga gtcttagggc cagacaagac catccaaccc
    56941 acacggaaac ctgctatgcg gtgggatttt gacagaccat tcatgctgac acagaagaca
    57001 tctggtgcca agctcgccac aggcgtatgc acatgtccgt ccattaccat gcggtcatag
    57061 atttcatccg caaagataat caaatcgttt tgacgggcaa tctcaataat ctccagcaag
    57121 agttccttag gataaagggc tccagttggg ttatttggat tgataaggac aattgccttg
    57181 gtattggaag tgatttttga cttgatatcg tcaatatctg ggtaccattc cacagcttca
    57241 tcacagatat agtgaacggc atttcctcca gctaggctga cagccgccgt ccatagagga
    57301 tagtctggca ttggcactaa gacctcatcc ccattgtcca aaagcccctg catggacatg
    57361 acaatcaact cactgacacc atttccaagg taaatatcat caatatctac gtttgggaat
    57421 ttcttcagct ggcaatactg catgatggcc ttacgggctg agaaaatccc tttggagtca
    57481 gaatagcctt cactatcacg cgcattcata atcaagtcat gaatgacctc gtctggcgct
    57541 gtaaagccaa attctgctgg atttcctgta ttcagacgta aaatcttttc tccattcgct
    57601 cgcatccgca tggcttcttc caatacagga ccacggatat cataagcaac atgctctaac
    57661 ttactagact tgttatattc tttcatcttg tttcctcaat tcatcaggat agtaacatta
    57721 taccactaga aagagaatgc gacaagttta ctgaaatgtg ttactagttt cgtatagaag
    57781 aaaaaccttg ctaaaggcga ggttaagaac gtagagatag caggtatttt gcaaagacac
    57841 atcacatacc aaaagataaa cctagaaaaa gcaagcctag aaaggagtca taaagaagat
    57901 taaacatgag gaaaagcccc catatcatca agtaatccca acgcccactt cgttttgcaa
    57961 ctagaaataa gattagatgg tagagtacat gaaagactaa aaatccaata aaacttggat
    58021 aaagaagcgg taccagactc tctaattgcc agatcatgat cacttctacc aagactgaaa
    58081 ctaggataat tccataataa aggaaatttg atttttgaaa agagtttttc atcattctcc
    58141 cttccttcac ttctttcctg ctatcctttc ttttatttta tcatatattt atatagattt
    58201 taagccctaa tattcttttg aaaaatactt tttttgcttt acttctatag tgaaaaggtt
    58261 tacaattata gtaagaaaat ttcaggaggt ttcattatgg cacaacgtta ccaaaatatc
    58321 atggtcgcaa tcgatggttc taaggaagcg gacttggctt ttgtcaaggg agttcattct
    58381 gctctacgaa acgacgctaa actcaccatc gcacatgtca ttgacacacg cgctctccaa
    58441 agcgtatcca cctttgatgc tgaagtttac gaagaactcc aagtcgacgc tgaaagtctg
    58501 atgaaagagt acgaaaaacg tgctaaagat gctggggtag cagatgttca tatcgtcatt
    58561 gaaatgggaa atccaaagac cctgctagca cgtactattc cagatgccga ggaagtggac
    58621 ctcatcctcg ttggcgcaac tggtctcaac gcctttgaac gcctcttggt cggctcttca
    58681 tctgaataca tactccgcca tgctaaggtc gatttgctgg ttgtaagaga acaagaaaaa
    58741 accttataat cacaaagaaa aggagcccct agctcctttt tgtttacgat ttatttctct
    58801 ctttatggcg ttcgtaagcc ttgagctggc gctgcagttc ctttttaata gcaggttctg
    58861 gagcatattt ttcttcccaa ttatctggtt ttaagatttt atgggtcact ggatcaaaat
    58921 gagccttacc atctggaaaa attttcccca tattggcctg atggacaata tcaaaaatac
    58981 gttctgggtc cacccccatc aagacaaaac tgccgtaggt gaagtaaagc atgtcaatca
    59041 aggcatccac ttgccctatc aaatcttgct gagcaggtgt cttcttggct actttatctg
    59101 ctgccttatc aagggcctga tgaagttgcg atacagcttg accaaaatct tcttcagaag
    59161 gactggctgc tcgaacaaac tccaccaatt cttctatttt aaaaccagcc ctatgggttg
    59221 caccctctaa atcccaagct cgaggttctt cttgggttcg ttcatccatc atgtggtgga
    59281 aggtcttgac cttattgaaa tgatagtcac ggctgacaaa gactttttct gaagacaaaa
    59341 caccaaaatg ttccaaggcc ttgtggatcc catcttgttg attgctagtg gtaatgtgct
    59401 tggcagcttc cttgacactg ctactaccat ttcccatagc gaccgacata ccaacgccag
    59461 ccagcatttc aaggtcatta tctgagtcac caaaagccat gacttggttg aggtcaaagc
    59521 catattcttt cccaactcgg cgaatgcctt ctaatttaga atttccctga ttgatgacat
    59581 ccgatgcaaa aggattgcta cgtgtcaatt tcaagtcttc aaaatcagct gccgccttct
    59641 cagattcttc tggtgtcatc agcatcaaaa cttggtagat aggctgattc atcaggtgaa
    59701 gcaggtcttc ttccttttgg ggaacaatct tgctgaccat gcgattaaaa gactgactca
    59761 ccgtccgagt taaaacagag ggaacgaagc gactaattcg ttgagaaaaa gaacccagac
    59821 caaaggacat gattttagaa cccaacatgg catccttggt ccctagggca atctccgtgc
    59881 cctctttttt agcatagcta attagatggc gcaaatgtaa cttagaaata gggctcgtga
    59941 acaagactct gtctttacta aagatatact ggccattata ggttaccgca aaatccagat
    60001 ccaaatcgtc catcaattcc ttaacaaaaa aaggtcctcg ccctgtcgct acgccaacta
    60061 gtaccccttg ttctttgaca atcttaatcg cgtccttagt ggatttcaaa acactcttgc
    60121 gattgttgac caaggttcca tcgatatcaa aaaaaacagc tttgacttcc atcctatccc
    60181 aatctcccct tttgtgatac aatgattata ccacatttca gaaagagtga gtaaatcatg
    60241 cctaagaaaa tccttgtttt acatacgggt ggaactattt ccatgcaggc cgatgcttct
    60301 ggcgctgttg tgacgagttc agataatccc atgaaccatg tgtccaaccc acttgaagga
    60361 atccaagtcc acgccttgga cttttttaac cttccaagtc cccatatcaa acccaaacat
    60421 atgctggtcc tctaccagaa aattaaagag gaagcagata actacgatgg agtggtgatc
    60481 acacacggaa ccgatacttt agaggaaaca gcctatttcc ttgataccat ggaagttccc
    60541 catatgccta tcgttctaac aggagccatg cgtagctcca atgagctcgg tagtgatggt
    60601 gtttataatt acctaagtgc tttacgagtg gccagtgatg acagggctgc tgacaaagga
    60661 gttttggtcg ttatgaacga tgaaatccac gctgccaagt atgtcaccaa aacacatacg
    60721 actaatgtca acaccttcca gactccaaca catggccccc tcggtctcat catgaaacag
    60781 gaaatcctct acttcaaaac agctgaacct cgtgttcgct ttgaccttga tcacatacaa
    60841 ggtttagtcc ctatcatctc ggcttatgct ggtatgacag atgagctgat tgatatgctg
    60901 gatttagaac acttggacgg tttgattatc caagccttcg gagctggtaa tattcccaaa
    60961 gaaacggctc aaaaattaga aagccttctg caaaaaggaa tcccagtcgc tctggtatca
    61021 cgatgcttta acggtattgc cgagcctgtt tatgcctacc agggtggggg cgtacagttg
    61081 caaaaagcag gcgttttctt tgttaaagaa ctcaacgccc aaaaagcccg cttgaaactc
    61141 ctcatcgccc tcaatgccgg actaacagga caggctttga aagactatat ggaaggctaa
    61201 tactcttcga aaatctctgc aaaccacgtc acgtcgcctt accgtatgta tggttactga
    61261 cttcgtcagt tctatctaca acctcaaaaa catgttttga gctgacttcg tcagttctat
    61321 ctgcaacctc aaagcagtgc tttgagctga cttcgtcagt tctatctaca acctcaaaac
    61381 agtgtgttgc gcagccttta accagccgcc tagtccgctc tatggtattc attaagtcaa
    61441 catctcttgt ttaagagcac aaaatcagga aatcttctcg attccctgat tttttctatt
    61501 tacgttttcg tgttgagcta cgttctgtca aaccatgagg taagagaact tcacgttctt
    61561 ccaactcttc cttatgcata atcttggtca acatacgcat actaatggca ccaaggtcat
    61621 aaagaggttg ggcaatcgtt gtcaagtttg gacgggtaaa gcgtgagatt tgtgaatcat
    61681 cactagtaat aatttcaaaa tcttctggca cagaaacacc cttatcagcc aaaccgttca
    61741 agactcctgc tgccaactca tcacctgtca caactgctgc agttgcattt gatgaaatca
    61801 aacgctctgc taaggcgtaa ccatcatcat agctatattt agattcaaat accaaaccct
    61861 cactataagc gattcctgct tttttcaagg tttccttgta gccaactaaa cgaaccttac
    61921 cattgatgtc atccactagc ggaccgctaa cgaaagcaat acgctcattt tctttagcaa
    61981 ggtaactcac tgcatcaatt gttgcttgct tatagtcaat attgacactt ggcaactggt
    62041 gctcaacatc gacagttcct gcgagaacaa tcggagtacg tgaacgcgaa aattctgagc
    62101 gaattttatc tgtcaagtga taacccatat agataatgcc atctacctgc tttgaaaaga
    62161 gggtattgac aacagaaact tctttctcgt tatcttcatc gctattagct aggacaatat
    62221 tgtacttgta catttctgca atatcatcaa tccccttagc caaactcgaa aaataaccat
    62281 tggtaatatt tggaatcacg acaccgacag tggttgtctt tttacttgca agaccacgcg
    62341 caactgcatt tggacgataa tccaagcgat caattacctc tagcactttt ttacgggtat
    62401 tctcttttac atttttattg ccattgacca cacggctgac cgtcgccatg gaaacacctg
    62461 cttcacgagc gacatcataa atggttactg tatcatctgc attcattcct tttcctgtcc
    62521 tttctatctc acacattctt ttacaagtag aggtactgat tgaagctcta tatctactta
    62581 caaaagtgaa gatgtgaaaa tttcgttttc atatttctac ttattccatt ctatcactaa
    62641 ttgtaaacac tttcaagtgt tttttgaaga ttgattgaaa aaatttcata gaaaacctag
    62701 gtttagctcc ttgctaccac cttagactaa acaaaaagga ggaaactaag ccctcctaaa
    62761 gttatagtaa aatgaaataa gaacaggata aatcgatcag gacagtcaaa tcgatttcta
    62821 acaatgtttt agaagtagag gtgtactatt ctagtttcaa tctactatag gtattgttcc
    62881 attcactacc gtcaatttta gcacatagtc ttcatgaaaa tattatatca tcataaccaa
    62941 ccagattctt ttgcgatatt agctgcctct gttcgattac cagcatccaa ttttgaaaga
    63001 atattggtga catagtttcg aatagttccg tttgagaggt aaagctgatc tgcgatttct
    63061 tggttggata agccccgggc gatccccttt aagacagcaa tctcttgttc tgtcaacgga
    63121 ttgggacggg tcatcaccac ttccatcaat tcaggcgaat actccttgcg tccttcgagg
    63181 acggtgtgca aggtttgcat gaggtctgca acgcttcgtt cctttaatac ataagcatcc
    63241 actccagcct tgaccgcacg ttcaaaatac ccagcacgct tgaaggtcgt caccacaacc
    63301 acctttgttt caagcctttc tgatcgtatc cactccaaga cttcaagacc tgtcttaaca
    63361 ggcatttcta cgtcaaggat ggcgatatct acagactcct tttctaatag ttggattgct
    63421 tcttgcccat tcttggcttg aaggacagac tccacatctg gttgaagcgt gagcaattga
    63481 cacatggcat ctcgcaacat actttgatct tctgcgacta atactttcat cttagtttct
    63541 ctccttataa ggtagtcgaa cttgcacttc cgttggatgt ttctgactga ttacacttac
    63601 ttctcctgaa aatggaaaaa cacgatctcg gattgtatgg agctcatctc cttttagaaa
    63661 agcaaagccg cagccatcat cacttactgt taaaatgagt tccttctctg tccgttctaa
    63721 ttttaagtaa gctttagacg ctttggcatg tttgatgata ttggtcacca actcaagcaa
    63781 aatcatagaa gccattgact ccaattcttg agtaaggcta gcagtatcta gttggttatc
    63841 cgtttccacc tcaattccag caatttctaa catctttttc acagtctcta gttcggatgt
    63901 caaagttcta gacttaagat tttccacaat ggttcgaact tcacgcattg attctttgct
    63961 aatttgctgt atttctctta attccttttc cacttgtgga taagcctgca tttgaaatag
    64021 ctgcaaggct agatctgtct tgacactaag catagcaaag gtatgtccca gactatcatg
    64081 caaatcctga ccgatacgat tgcgctcatt ttctgctagc aatagattta tctgggtatt
    64141 ttgcttgacc tgagcttctt tcaaatcctc gacaaggcga attcgaaccg agcccaaagt
    64201 catcaaatcg acaaaagtaa gaattacaag catatagact agaaactcaa cttcgattct
    64261 ctgaaaaatc aaaagtcgcc ccacaacaag gacttgagca aggagaaatg tccatacatg
    64321 taaagacttt aaactacgta cgccaaaatg ataaattaag agattggaaa ggaaaaagaa
    64381 aaaccagata taattcccag caacaaaggc ggtattccca gctacataga ccagcatgat
    64441 cccccagaaa agccatgata tgcgctggtt cttagttatt aaaacaccca aatacgtcac
    64501 tacaaataga atatcaacca ataaatgcca agcaggaagc tccccagtca ctacaggtag
    64561 gatggggaaa atcataaaaa ttaaacttgc ccaaaacata tagtgtatgc ttttcagtct
    64621 ttcaagcatt aagcattctc cttatgacct tgaaggtaaa tggtcaaacc aaacaaaact
    64681 gctgaaaaaa caagtagata aactgtggct gatagattga tgccaccctc gtttaagaag
    64741 gtcttgagca actccatcaa ttgataggtc gggagacact taccaactgc ttgcatccag
    64801 tctggaaata aagaaatggg catccagagt ccgcctaaaa cagccaatcc tagataaaga
    64861 agattgccca caacagacat cagctgacta gttggtaaga gagtcaaggt caagccaagt
    64921 gctacaaaag caatactccc cacaatcagc aaaatcgcag ctccaaccca ttttactaga
    64981 ggcatgtcta cacctcttac aaaatgtcca actgtaaaaa caaccagaat tgagaccaaa
    65041 taatcaacca gcatacttgt tatctttgat agataatatt ctaccatatt tacagggcta
    65101 tgacgcaatg ttttctgcca gttgttcatc ttatcggtat gtaaaacagc tggaaatgag
    65161 aggatagttg tcgacatcat ggaaaaggca gtcatggaga tgaggtaatc acgcataaaa
    65221 ttcgcgagtt cacctggtgt gtcctgatag ataccagaaa aaaataaata gaaagccgtc
    65281 ggcatcccta ccgacaatag ataatagatt aattgtcgtt tggtcaataa aaattctatc
    65341 ttactaagtg ctatccatcg tttcatctta gttatctccc ttctgcgtct cttcaaagat
    65401 tgtattcaac aaactacgat tattaacttc gatttcttgc atcctacatc ctgcttgggc
    65461 taatagttcc cagaaagcat ctgcttctcg agtgactact tgtaaagaat cttgctttag
    65521 ggtccagttt tcaaccaaat ttgactgctc tacgacttcc ttgtaagcta taggaaggat
    65581 aaagtgcttt tctatttcct cgctacgcat agctagaggc gtcgtatctc gaatcaactc
    65641 tcccttattt aagagcaaaa tgcggtctgc agtgtgttcc acttcctcaa tataatggga
    65701 cgaatagaga atggtgactc cttgcgcttt taactcctgg acaatttccc aaaaacgttg
    65761 acgagttgag gtatccatgg acgcagtagg ctcatctaaa aaaacaatct ttggtcgccc
    65821 aattaaggtc aagacgaaag aaaagagacg cttttgaccg cctgataatt tttctgccaa
    65881 ctgttctttt tgttgcttga caaactgcaa tagttgatca atttcctgat tgctcaaagg
    65941 atttggatag atacgttgaa agaaagcaat caactcttta acttttaatt tctgaacgat
    66001 tacattttct tgagggaggt aagccctagt atagtctaac ttagaactcg tcactggtaa
    66061 accttgaata gatacttgac cgcttgtgac cagtttatct ccaagcaaac aatctaagag
    66121 tgttgtcttt ccggcaccat ttggaccaat taaggcaaca cattcaccat cgttgatttc
    66181 aaaggagata ttccgcaaaa tttccttgtc ttttattttc ttactcaatt tctcaacttt
    66241 aaccaccgtc atgagactct cctttcaacc actccattcc cataaggaaa acgacgaaaa
    66301 tcataaatcc aaaccccaaa gcaccacgaa tgaattggcg aagcaaggct tgatcaaacc
    66361 aatcagtaaa catttccact aaccatacca agagtgacag gccgataaag aaatagatga
    66421 tccctctctt cattcctcaa actccttttt cacatctctg actaatttca aaccttctct
    66481 aacaagccaa gacatgattc caaagccagc aaagaccttc caaggaaaat ggtagaaatc
    66541 ctcatccaat cccgaaaaca tgagataggt cataactcct gctactacta aacttactgc
    66601 gataatcatt ttatttctca tctcttcttc ccccatttca tactacaatt atagtctttt
    66661 aaaatcagag gagacagaag cttctgtcac taaaaaatat gacaaatgtc ataaaaaatt
    66721 ctgttcaaaa caagcaagat acactataca ataaaacaca atcagaaaaa tctaaggcaa
    66781 cttcctcaaa agagatatca aacccaattc acaccataat gtaaactaat acttatttaa
    66841 aatcaaaaag agtaaaaatt tttatcagac aaacacatat atagtgtatt gaatctataa
    66901 cagtaggcct taaatactaa aatatttcta taaattaatt taactttcct gatagaactg
    66961 ttcatatctt atttcaattc tctatattat acgttgaacc aaacccttct attgctttct
    67021 taaaaattta taagagttat aaaatctgtt aaatttcaat gtgtatatct aaactacggt
    67081 atttattgaa aagactggag acaaaaagta tacgctgcca aaatgaatta ctgaaaatca
    67141 aaaaagagag aaccaaactg attccctctt aatgtatata atatctagtt ttaaaaatac
    67201 acactcacat atctctgt
//
LOCUS       DBERXF010000007        60044 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.07, whole genome shotgun sequence.
ACCESSION   DBERXF010000007 DBERXF010000000
VERSION     DBERXF010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 60044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.07"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(216..2174)
                     /gene="ftsH"
                     /locus_tag="ACL8JK_000497"
     CDS             complement(216..2174)
                     /gene="ftsH"
                     /locus_tag="ACL8JK_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGS1785436.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2190..2732)
                     /gene="hpt"
                     /locus_tag="ACL8JK_000498"
     CDS             complement(2190..2732)
                     /gene="hpt"
                     /locus_tag="ACL8JK_000498"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGS1785437.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2736..4013)
                     /gene="tilS"
                     /locus_tag="ACL8JK_000499"
     CDS             complement(2736..4013)
                     /gene="tilS"
                     /locus_tag="ACL8JK_000499"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGS1785438.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(4010..5278)
                     /locus_tag="ACL8JK_000500"
     CDS             complement(4010..5278)
                     /locus_tag="ACL8JK_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGS1785439.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQY
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5271..5393)
                     /locus_tag="ACL8JK_000501"
     CDS             complement(5271..5393)
                     /locus_tag="ACL8JK_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HGS1785440.1"
                     /translation="MENLLDVIEQFLSLSDEKLEELADKNQLLRLQEEKERKNA"
     gene            complement(5398..5766)
                     /locus_tag="ACL8JK_000502"
     CDS             complement(5398..5766)
                     /locus_tag="ACL8JK_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGS1785441.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5759..6025)
                     /locus_tag="ACL8JK_000503"
     CDS             complement(5759..6025)
                     /locus_tag="ACL8JK_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGS1785442.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(6083..9592)
                     /gene="mfd"
                     /locus_tag="ACL8JK_000504"
     CDS             complement(6083..9592)
                     /gene="mfd"
                     /locus_tag="ACL8JK_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGS1785443.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKEIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQGYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRIKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9593..10162)
                     /gene="pth"
                     /locus_tag="ACL8JK_000505"
     CDS             complement(9593..10162)
                     /gene="pth"
                     /locus_tag="ACL8JK_000505"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGS1785444.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKKFEKTMQRYNG"
     gene            complement(10233..11348)
                     /gene="ychF"
                     /locus_tag="ACL8JK_000506"
     CDS             complement(10233..11348)
                     /gene="ychF"
                     /locus_tag="ACL8JK_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGS1785445.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11432..11626)
                     /locus_tag="ACL8JK_000507"
     CDS             complement(11432..11626)
                     /locus_tag="ACL8JK_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HGS1785446.1"
                     /translation="MYQVGNFVEMKKPHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKINKIID"
     gene            complement(11691..12827)
                     /gene="dnaN"
                     /locus_tag="ACL8JK_000508"
     CDS             complement(11691..12827)
                     /gene="dnaN"
                     /locus_tag="ACL8JK_000508"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGS1785447.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12986..14347)
                     /gene="dnaA"
                     /locus_tag="ACL8JK_000509"
     CDS             complement(12986..14347)
                     /gene="dnaA"
                     /locus_tag="ACL8JK_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGS1785448.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14560..15318)
                     /locus_tag="ACL8JK_000510"
     CDS             complement(14560..15318)
                     /locus_tag="ACL8JK_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGS1785449.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15376..16557)
                     /locus_tag="ACL8JK_000511"
     CDS             complement(15376..16557)
                     /locus_tag="ACL8JK_000511"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HGS1785450.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16740..17219
                     /gene="rlmH"
                     /locus_tag="ACL8JK_000512"
     CDS             16740..17219
                     /gene="rlmH"
                     /locus_tag="ACL8JK_000512"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGS1785451.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17263..17336
                     /locus_tag="ACL8JK_000513"
     tRNA            17263..17336
                     /locus_tag="ACL8JK_000513"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17297..17299,aa:Arg,seq:tct)
     gene            17501..17626
                     /gene="comC"
                     /locus_tag="ACL8JK_000514"
     CDS             17501..17626
                     /gene="comC"
                     /locus_tag="ACL8JK_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HGS1785452.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17647..18972
                     /gene="comD"
                     /locus_tag="ACL8JK_000515"
     CDS             17647..18972
                     /gene="comD"
                     /locus_tag="ACL8JK_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system sensor histidine kinase ComD"
                     /protein_id="HGS1785453.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18969..19721
                     /gene="comE"
                     /locus_tag="ACL8JK_000516"
     CDS             18969..19721
                     /gene="comE"
                     /locus_tag="ACL8JK_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system response regulator
                     transcription factor ComE"
                     /protein_id="HGS1785454.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19773..19844
                     /locus_tag="ACL8JK_000517"
     tRNA            19773..19844
                     /locus_tag="ACL8JK_000517"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19806..19808,aa:Glu,seq:ttc)
     gene            19850..19923
                     /locus_tag="ACL8JK_000518"
     tRNA            19850..19923
                     /locus_tag="ACL8JK_000518"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19884..19886,aa:Asn,seq:gtt)
     gene            complement(19964..20506)
                     /locus_tag="ACL8JK_000519"
     CDS             complement(19964..20506)
                     /locus_tag="ACL8JK_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGS1785455.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20685..22288
                     /locus_tag="ACL8JK_000520"
                     /pseudo
     CDS             20685..22288
                     /locus_tag="ACL8JK_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(22318..24870)
                     /locus_tag="ACL8JK_000521"
     CDS             complement(22318..24870)
                     /locus_tag="ACL8JK_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGS1785456.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYIIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24932..26554)
                     /locus_tag="ACL8JK_000522"
     CDS             complement(24932..26554)
                     /locus_tag="ACL8JK_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1785457.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26760..27785
                     /gene="trpS"
                     /locus_tag="ACL8JK_000523"
     CDS             26760..27785
                     /gene="trpS"
                     /locus_tag="ACL8JK_000523"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGS1785458.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27937..29415
                     /gene="guaB"
                     /locus_tag="ACL8JK_000524"
     CDS             27937..29415
                     /gene="guaB"
                     /locus_tag="ACL8JK_000524"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGS1785459.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29466..30563)
                     /gene="recF"
                     /locus_tag="ACL8JK_000525"
     CDS             complement(29466..30563)
                     /gene="recF"
                     /locus_tag="ACL8JK_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGS1785460.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSVQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNTTDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(30566..30934)
                     /gene="yaaA"
                     /locus_tag="ACL8JK_000526"
     CDS             complement(30566..30934)
                     /gene="yaaA"
                     /locus_tag="ACL8JK_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HGS1785461.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            31093..32343
                     /locus_tag="ACL8JK_000527"
     CDS             31093..32343
                     /locus_tag="ACL8JK_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGS1785462.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKGWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            32340..33623
                     /locus_tag="ACL8JK_000528"
     CDS             32340..33623
                     /locus_tag="ACL8JK_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGS1785463.1"
                     /translation="MTKVVFEKKYYPAVKEMIYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLYLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFSWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33665..34486
                     /gene="rodZ"
                     /locus_tag="ACL8JK_000529"
     CDS             33665..34486
                     /gene="rodZ"
                     /locus_tag="ACL8JK_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HGS1785464.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34497..35042
                     /gene="pgsA"
                     /locus_tag="ACL8JK_000530"
     CDS             34497..35042
                     /gene="pgsA"
                     /locus_tag="ACL8JK_000530"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGS1785465.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            35039..35866
                     /locus_tag="ACL8JK_000531"
     CDS             35039..35866
                     /locus_tag="ACL8JK_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGS1785466.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35851..36690
                     /locus_tag="ACL8JK_000532"
     CDS             35851..36690
                     /locus_tag="ACL8JK_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HGS1785467.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36683..37477
                     /locus_tag="ACL8JK_000533"
     CDS             36683..37477
                     /locus_tag="ACL8JK_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS1785468.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37536..38354
                     /gene="mreC"
                     /locus_tag="ACL8JK_000534"
     CDS             37536..38354
                     /gene="mreC"
                     /locus_tag="ACL8JK_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGS1785469.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38354..38848
                     /gene="mreD"
                     /locus_tag="ACL8JK_000535"
     CDS             38354..38848
                     /gene="mreD"
                     /locus_tag="ACL8JK_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGS1785470.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38942..40120
                     /gene="pcsB"
                     /locus_tag="ACL8JK_000536"
     CDS             38942..40120
                     /gene="pcsB"
                     /locus_tag="ACL8JK_000536"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HGS1785471.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40344..41123
                     /gene="rpsB"
                     /locus_tag="ACL8JK_000537"
     CDS             40344..41123
                     /gene="rpsB"
                     /locus_tag="ACL8JK_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGS1785472.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            41202..42242
                     /gene="tsf"
                     /locus_tag="ACL8JK_000538"
     CDS             41202..42242
                     /gene="tsf"
                     /locus_tag="ACL8JK_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGS1785473.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42488..42811
                     /gene="tnpB"
                     /locus_tag="ACL8JK_000539"
     CDS             42488..42811
                     /gene="tnpB"
                     /locus_tag="ACL8JK_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS1785474.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
     gene            complement(42952..43239)
                     /locus_tag="ACL8JK_000540"
                     /pseudo
     CDS             complement(42952..43239)
                     /locus_tag="ACL8JK_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            43221..43750
                     /locus_tag="ACL8JK_000541"
                     /pseudo
     CDS             43221..43750
                     /locus_tag="ACL8JK_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(43825..44745)
                     /gene="cysK"
                     /locus_tag="ACL8JK_000542"
     CDS             complement(43825..44745)
                     /gene="cysK"
                     /locus_tag="ACL8JK_000542"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGS1785475.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(44994..45629)
                     /locus_tag="ACL8JK_000543"
     CDS             complement(44994..45629)
                     /locus_tag="ACL8JK_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGS1785476.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHGLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            45685..46983
                     /locus_tag="ACL8JK_000544"
     CDS             45685..46983
                     /locus_tag="ACL8JK_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS1785477.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQVVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            46980..47642
                     /locus_tag="ACL8JK_000545"
     CDS             46980..47642
                     /locus_tag="ACL8JK_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGS1785478.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQFWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            47722..48270
                     /gene="raiA"
                     /locus_tag="ACL8JK_000546"
     CDS             47722..48270
                     /gene="raiA"
                     /locus_tag="ACL8JK_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGS1785479.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            48406..50379
                     /locus_tag="ACL8JK_000547"
     CDS             48406..50379
                     /locus_tag="ACL8JK_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGS1785480.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDETSESDISQINSFVANFISEFSEKHMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            50376..50828
                     /gene="rplI"
                     /locus_tag="ACL8JK_000548"
     CDS             50376..50828
                     /gene="rplI"
                     /locus_tag="ACL8JK_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGS1785481.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            50872..52224
                     /gene="dnaB"
                     /locus_tag="ACL8JK_000549"
     CDS             50872..52224
                     /gene="dnaB"
                     /locus_tag="ACL8JK_000549"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGS1785482.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            52226..52492
                     /locus_tag="ACL8JK_000550"
     CDS             52226..52492
                     /locus_tag="ACL8JK_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGS1785483.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            52581..53927
                     /gene="cbpD"
                     /locus_tag="ACL8JK_000551"
     CDS             52581..53927
                     /gene="cbpD"
                     /locus_tag="ACL8JK_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HGS1785484.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGETHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      54010..54112
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            54183..54473
                     /locus_tag="ACL8JK_000552"
     CDS             54183..54473
                     /locus_tag="ACL8JK_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HGS1785485.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVPMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            54436..55194
                     /locus_tag="ACL8JK_000553"
     CDS             54436..55194
                     /locus_tag="ACL8JK_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1785486.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            55233..56240
                     /locus_tag="ACL8JK_000554"
     CDS             55233..56240
                     /locus_tag="ACL8JK_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1785487.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEASKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            56240..56968
                     /locus_tag="ACL8JK_000555"
     CDS             56240..56968
                     /locus_tag="ACL8JK_000555"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785488.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            57087..57545
                     /locus_tag="ACL8JK_000556"
     CDS             57087..57545
                     /locus_tag="ACL8JK_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGS1785489.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            57547..59979
                     /locus_tag="ACL8JK_000557"
     CDS             57547..59979
                     /locus_tag="ACL8JK_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGS1785490.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVYAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
BASE COUNT        18640 a        10349 c        11830 g        19225 t
ORIGIN      
        1 ggtcccaatc cgacaattcc cataaatgaa ggtaatattc atttctacac ttatacacag
       61 tcccttggac ttcttcatac aattctttaa tcataatttt cccctttcta gatacagtct
      121 aacagattag aaaacacatt tgttccattt tctccattct gttcccttta gctcctaaac
      181 tgcacaaaaa agagaggctc cagcctctct cagggttatt tttcgtcatt catttttgac
      241 tttacttcat cataggatag tgcatgagat tcctcttcta ctgcttcagg catctttcct
      301 gtttcgtaaa gagctttaat ttgtgtacta tccaatgttt cgtatttcaa taatgcttct
      361 gcaattaact tgtgagtttc acgatttgac tgaataattt cagcagcttt atttcgtgcc
      421 tcatttaata atgaacgaac ctcttcatca atttcataag ctgtttgttc tgaaattgat
      481 ttttgaggac tctgtgcacc aagcatagca tggtttcctt catattgtac tgggccaagt
      541 ttttcactca taccgtactc tgtaaccatt gcacgtgcca tttgtgtcgc ttgttcaaag
      601 tcgtttgaag ctcctgtggt ttggacatta aagataattt cttcagctac acgtccaccc
      661 attaagccag ccaattgctc tttcatatct tctttagata gaagcatttg atcctcttta
      721 ggaagtgcaa tcatgtatcc gcctgcacgg ccgcgtggta caattgtaac cttatggaca
      781 acgcgagcat tcgacaagac tagaccaaca atggtatgtc ctgcctcatg gtaagcaacc
      841 aattctcgtt ctttttgtga aactgtctta tctttcttag aaggtccagc aataactcta
      901 tcttctgctt catcaatatc tgaagcatca attatcgatt tattgcgacg agcagcaact
      961 aaagctgctt cattcaagac attctctaaa tcagcaccaa caaagcctgg agtttgttga
     1021 gccactaatt tcaaatcaac atcttctgct aaaggcttat tcttagcgtg aactttcaag
     1081 attgcttcac gacctttaac atcaggacga ccaaccaata cttttctatc aaaacgtcct
     1141 ggacgcaaaa gggcagggtc aagtacatct gaacggtttg tcgcagcgat gacgataatc
     1201 ccttcatttc cctcaaaacc atccatctca atcaaaagtt ggttcaaggt ttgttcacgt
     1261 tcgtcattac ctccgccgag accgactcca cgttgacgtc caacagcatc aatttcatcg
     1321 ataaagatga tagctggtgc tgcttttttg gcatcctcaa aaagagagcg aacacgacta
     1381 gctccaactc cgacaaacat ttctacaaag tcagaacctg agatactaaa gaatggaaca
     1441 cctgcttctc cagcgactgc cttagcaagc aaagttttac ctgtccccgg aggtccctcc
     1501 aaaagaacac ctgctggaat acgggctcca agttttgtga atcgttttgg atcttttaag
     1561 aactcaacaa cttcaactag ttcttgtttt tcttcttcag ctccagcaac atctgaaaat
     1621 cttactttaa tatcttcttt atttgctgct ttagccttac tacgtccaaa actcattgga
     1681 ttacggccat tgcctcctcc catatttccc atcatagaga ataggaagaa gaatagaatt
     1741 ccaaatggca caatggatac gagtagatta atccatatac cacttgaact ttcatgctta
     1801 acagttactt ctgctttatg gtcagtagca agtttttgca attctgatac ggtagtatct
     1861 gcaggaagaa tagtgctggt aaatttctct accttagtaa cagatggcgt gaaaaactga
     1921 atacctgttc cttctttact tgttttagga tttttataga caccagaaac ttcgataaca
     1981 ctaccatttg gttggtaagt taattctttt acattaccat cggtaatttc ttgtaccaac
     2041 tcagtatagt tgatttgctg acttcctcct gagttattcc cagaatagaa atactggaat
     2101 cctgtcacaa ggaaaaagat aaataataac catagaaaag gatttttaat taaaccatta
     2161 ttttgttttt tcattaaaga ttattctttc taatttgaat acacttcctc tttcaatact
     2221 ccaatataag gaagattacg ataattttct ttgtagtcta aaccataacc tactacaaac
     2281 tcatttggga tagtaaagca ggtatagtct gcctcaattt ctacaacacg tccttctggt
     2341 ttatccaaca aggttgcaat tttaacagaa gctgcttctc tttctttaaa catatctcgc
     2401 aaattcttca aagtttgacc tgtatcaatg atatcttcta caaatagaac atgtcttcct
     2461 ttgatatctt gagtcacatc ttgtttaata ttgataacac cactacttgc tgttccacca
     2521 tggtagctag aaaccatcat gaagtccatt tcaatatgtg tatcaatatg tttgaccaat
     2581 tcagccataa aaggaataga tccttttaaa atcccaacta agattggatt ttttcctgca
     2641 tagtctttag ttaattgagc acctagtttt ttagctgctt ctgtaatttc atcgtgtgaa
     2701 acgaggactt ttttaatatc gttttctaac attttttacc tatctatttt ttctatataa
     2761 agtacagtgt tcattatatc atttttcgtt tttttactca aattattggt cgcaattccc
     2821 aaaattgaga caatttcacc aaattgctca ataataagag cagagtttct cttttccata
     2881 gggattttca aatcaataaa taaacgtctg agtttttttc tatgcccatt ttgaatcaaa
     2941 acatctcctg tttttcgatg acgaatgtgt atggatgttt cacgtgaaac aggtatttgt
     3001 tgaattaatt caccttctaa tggaagtcca aaggaaaata aatatccttg ataagctacc
     3061 tgattttgat agtgtaacac aagttcatct tccttttcat cagcctgcgg actgatttta
     3121 caaatctgaa actgttggta ctcttttatc aattcatagc catttttaat cggatgacga
     3181 tactggcttt tagattttaa aatctgctga acttcagcaa actgagcttt tgtaagattc
     3241 aaatctggaa aacgattcag ataagtttga agtaaaactc tttgtgtaga ctcagagtaa
     3301 gaaaataact gctgtaaatc ttccacatta atattgttag ataattcagc tattgccaaa
     3361 tcataatcta aaatttcatt gccaatgcct aagattgcat ccctaaatcg aggattttct
     3421 ttttccaatt ctggtaagta agagtttcga atacgatttc gaaaataatg attctcctga
     3481 tttgatgtat cttcaaagtg aaaaattgat ggaaagtctt ttttctgaaa atgcaagaag
     3541 ggacgaatga tttctatctc tccgactact tgcttctcct taattcctga tagatagcgc
     3601 aagcgagttc ctcgaatcaa gcgcatcaaa atcgtttcca cctgatcatc agcatggtgg
     3661 gcagtgacta aagctgtcgc acctgtcttt ttcataacct cttgaaaaaa atcataacga
     3721 aaatttcgtg cacgcgcttc tgaaaattct cctgaaaaat tgctgatata aataggaagc
     3781 tctgcttcag cagccaactt ccttaattcc ttttcttccc aatctgattc aattctctgc
     3841 ttatgattca catgagccag aatcaattca atctctaact ctttttgata agtagacaat
     3901 accttaaata gaaacataga atctaatcca ccagaaagag ctagaaccgc cttagcatgc
     3961 tttttgaaat atcccttctt gagaaaatga tttaaaaaat ctggttccct cattttagaa
     4021 cctcataaac atccttggct atcttagaaa tcgtatcata atcagaattc ttagtgaaaa
     4081 tagaaagaat aaatggagaa tctgcataga caacacccgt atcatgctta aattcatccg
     4141 catctccaat tttatgagct actttaacag aaacaccttt ggcaattcgc tgactatcaa
     4201 aatctgtttt agtcaaagac tctagcacaa atccattttg attataaata gcttccataa
     4261 acttcccggc catcttagaa gaaatcaatt tttcttttgg atcccaatca tctcccataa
     4321 tggcagacat cttggatttg aatgtggcat cagattggtt tgaaatgtaa tatcccaata
     4381 gattatgagc tacattatca gattcttttg atactttcgt aattaaatcc tttaaagaat
     4441 attctttatt atcttctttt ttaggaagac taccacttcc ctctggttta taagaacctg
     4501 gaaaatcatt gactgcagat acgtatttta cagtcgtatc taactgataa agaccctcat
     4561 ttattttttc ttgcgtataa tagagatagg agagtttcaa aacgctggct gcatacatct
     4621 tttcatattg attgatacca gcttcttttc cagtagtcag ttgcttaaca taaatagaga
     4681 aagaatcttt ctgatatttt tcagataaca tttcttgaac tttactcatc cgattatctt
     4741 cttcagaagt tgattcttta gctacccatc cagcctgatc aatatgtaga aattctcttc
     4801 cttctacaaa catggtcttg tcgattgata cttgcgaata agctgataag gatgatttca
     4861 cttcttttaa atcataagga ctattgtaca gtttaaagtc agattctaac catacttttt
     4921 ttattgttgg agttacctct gattgatcat ataaaaatcg tttgtccgca gctataaatt
     4981 gatgatttga tagcttaaat actggaattc cttgtttatt taagcgccac tcggttattt
     5041 gaaaacttgt tttgggagtc aatttcccag attccactac taaatcttca ttcgcataaa
     5101 caggaacctc tccataaacc atgggagaac ttaatttttc tctaaaataa ataccaaagt
     5161 cagattgtga aaggtaataa atttctttcg aagtatagac gacttctttt tctgtgctaa
     5221 cgacttttga aatggtcaaa aaacttggta gcaacaaaat aattaagaat ttacgcattc
     5281 ttcctttcct tttcttcttg taaacgcaat aattgatttt tatcagccaa ttcttccagc
     5341 ttttcatctg acaaactcaa aaattgctct attacgtcta ataaattttc cattttatca
     5401 cctttgaagc aagtcaggaa tcgtataaac tttttccctc gacttagaat aatagtactt
     5461 cgctcgtgta tatttagcag cataatcttc atctttcaac ttggtagcaa atgctgtctc
     5521 cttatccttt tcatcactca aagtttgata ctgagtttgc aagtctgcta attgctgacg
     5581 tctttggagt aattgctgat aactctgcgc taaattaaaa gttggcaaga taaataatag
     5641 cataatcaaa atcaataccc ctcccataaa acgattccgt ttttgtcgtt ctttcatcag
     5701 gtagcgacga cgttggtatt cattttgaat aaaagaatta ttcaattgta caatattttt
     5761 agacattttc ttctacccgt gtttcactga taatttcata cattcctgct gcatcttctt
     5821 tttttgtact atctttcatc tctagtactt ttacaagcag caacttattg ccaaagcgaa
     5881 tttcaacttg gtcattaact ttcaagtccg ttgaactttt ggccaagatt ccattaacct
     5941 tgattctacc tttatctgct acttcctttg cgactgtacg acgcttgata attcgcgata
     6001 cttttaaata tttatctaat ctcatcctta ttacctcaat ttattattgt accattttta
     6061 tctattttat agaagaaaaa tatcaaatgg aattttcttc cttagactct tttatctcta
     6121 ataaactttc tccaaaaatc agcaaacctt ctaaaatttc ataatctttc ttattttgga
     6181 catcaaatac aagctccatt aatcccttat tctcagcgat gcctgctttt aagttcgtta
     6241 cggataaagc tttaaaataa tcttgagcta aaaacagtcg ttgagtgact ttttcaaatt
     6301 gaattgtaat tttattatct tttctttcca cacgttgaac aaagaccttg tccaagtatg
     6361 atttgaccaa accaatctct aacagatagg ctactacatc tgggtattct ccaaaacggt
     6421 ctatcaactc ctcttgtaac tcttcataat tgacacggtt gtcaatttga cgaattttct
     6481 tgtaaatttc aatcttatgt cgttgatcag aaatataagt atcaggaaga taggcatcaa
     6541 tttgcaaaat caactcagca ttccctttga ttcttgtgtt agcgttagca ttaccgtttc
     6601 gtttagcaat agcttcctct aataactgcg aatacaattc aaaaccaaca gaatcaatga
     6661 aaccagactg ggattttcct aaaagatttc ctgctccacg aatcgaaaga tctcgcattg
     6721 caatcttaaa gccagagccc aattctgtaa atcctttaat cgcttctaat ctcttttcag
     6781 agacttcact gattgatttt tctggacgat acatgagata agcataagca atacgattac
     6841 tacgaccgac tcttcctctt aactgatata aggttgacaa gcccatatgg tccgcatttt
     6901 caataaataa agtattagca tttggaatgt ccacccctgt ctcaataata gtagtcgtca
     6961 ccaagatatc gtattgtccc tcaataaagt ctaatagagt attttccaac tggacttcac
     7021 tcattcgacc atgaacatat ccaatcgaag cctctggaat caactcctgt aattctgaaa
     7081 ccttctgaac aattgtgtca actttgttgt aaagatagta accttgacct ccacgctcca
     7141 tttcacgcaa gacagcatca cgaatgacac tatcattctt ttccaaaaca taggtctgaa
     7201 cagggtagcg attagtcggc ggagtttcaa taacagacaa atctctgatt cccagcatag
     7261 acatatggag ggtacgaggg attggcgtag cggtcaaggt taggacatcc acttgtttct
     7321 tcagttcttt caaagtttcc ttatgcttga caccaaatcg ctgttcctca tcaataatca
     7381 tcaagcccaa atcagcaaac acaacatctt ttgacaaaac acgatgtgtt ccaatcaaaa
     7441 tatcgacttg accgtttttc aatttttcaa gtgttgcagt ctgctctttt ttacttctaa
     7501 agcgactcaa cacatcaaca ttaactgcaa aattttggaa tcgttcctta aaattcgtat
     7561 agtgctgttg cgctaaaacc gtcgtcggaa ctagaatgac aacctgtttg tgatcattga
     7621 ctgctttaaa ggctgcacgc atagcaactt cagtctttcc aaaaccaaca tccccaacta
     7681 aaagtcgatc cattggctga gaagcctgca tatccctctt gatttcctca atactacgaa
     7741 gttgatcatc cgtttcaaca taagggaaag catcatcaaa ggcatcttga tcatcatcat
     7801 cagctgagaa agcaaaaccc ttcaactgac tacgttcaga gtagagtttg attaaatcat
     7861 cagctatatc ctctacctgg ttcttaacct tttgcttggc ctttttaaaa tgaccgtcat
     7921 ttaatttatt gagttttgga gctttaccat cacttgaaat atatttggac agtagatgaa
     7981 tctgttccac gggaatagaa atttgatcac cattttggta ctggacactg acataatcac
     8041 gatgaatttc cttgatttca atggtttcaa ttcctagata ttgaccaatc ccatggatat
     8101 gatggacaac atagtcccct ttttcaagtt cattgtaatc ttttaatctc tctgcatttg
     8161 aaacatgttg tcttcgaaaa cgacgcttta atttcttttg aaaaatctca tgttcagtta
     8221 tcaataaaat cttttcatct acaaaatgaa aaccatgtct gagattaccc tctattaaat
     8281 ttacagattc tttacagata cttgtcttat ctctagaatc caatttaatc tgatattcct
     8341 ctaacatatc ctccaatgtt ttacttccca ttgaattgct agactgcaga ataatggtgt
     8401 aatccatttt tttatatcgt tcaatttctt cttttagaaa agaaaactga ttgaaaaatt
     8461 cctgcatagg atattgattg aattgataaa ttttgtcaaa tttgagattt cctaaaccct
     8521 tttgaagatt agagaaaaag gtcactggac tttgtttttt atagatttgt tcaatatcag
     8581 aaaaatactg catatcagaa aatgctttac tattctgtaa ttcttctgta aagtactgcg
     8641 ctaagtctct ttcaaagact tcatactgat tcatcaattt ttgataatca tcaaagaata
     8701 ttggagtatc tttttcaata taatcaaaga cagtccatgt cttatcatag cacaaagata
     8761 aaaacttccg agagtctgca tgactttgtt tttggtgaaa acttgaaaga atttcttcta
     8821 ggtatgattt caaaataggt gataaagttt ttgaaatttg tttttctaaa gctgactgtc
     8881 ctcgttgata atccttttct ctcaaaagca tatcactagc tggaaagata gtgagttctg
     8941 tcttattttc tttcgataat tgtgtttcta cttcaaatga cctgatacca tcaatttcat
     9001 caccaaaaaa ctcaattcga caaggttcta actgggatat ttcaaaaata tctaaaatat
     9061 ctcctcgaag actaaattcg ccctgagttt gtacttgagt aacttttcga tagccatttt
     9121 cctttaactg atggataaac gcgtgttgat catattcttc accaactgag atttttacaa
     9181 tactatcttt gaatgcattg ggagacggta aaatcaatcg acttgctgcg atattacaaa
     9241 ctaaaatccc tttcttagat gaatcagtca aaaaacgcaa ggcttcaacc cgtgaaataa
     9301 ttttttcctg tgaagacatc aaaaactcca ccataggagc atcatctacc aaaaatggat
     9361 agacgagttc ctcacccaag atagaaataa gatcactaac aagtccttct gcttctccat
     9421 aagttgacgt caataacaca atcctatctt ctttttctaa actgcttgca attgcaagag
     9481 ccttagtaga tgttgataaa ccaagtatta gttgtctttt cttatctgtt aaattttgat
     9541 gccatttttt aatctgatca ttttctgaga ataaatctaa taaggtcacc atttatccgt
     9601 tatacctctg cattgttttc tcaaattttt tctcttgtaa atagtagttt acagaatcgt
     9661 caactttgtc aacagactgt aaaataccga tataatcatc cctgtcaaac ttactcaaaa
     9721 catgatgaac aactgacata ccatttttag gtcttccaat tccaatctta acacggttaa
     9781 agacctgagt tcctatatgt tgaataatag acttgatacc attatgacca cctgctgagc
     9841 cttttgctct taaacgaatt ttcccaactt ccatgtcaag atcatcgtaa atgataagta
     9901 aatcgtcaat atccaaacca tagtaagtta ataaagcatg aactgctttt ccactttcat
     9961 tcataaaggt cgttggttta accagataaa ttttttctcc atttaggaaa aaggatgcta
    10021 ggtcagcttg aaatatctta tcgtgtgtaa aagtgacatt ctgtttcttc gctagttgat
    10081 caatcaacat aaaaccaaca ttgtgttttg tttcaaaata tttatcccct ggatttccca
    10141 agcctacaag taatttggtc atttattttt cctttcaaaa gccaaaaggg ttggaatttt
    10201 tttccaacct aattgacacc atttattaat ttttagacat taaagcggaa ttccatgatg
    10261 tcgccatctt gaacgatata ttcttttcct tcttcacgca agcgtccagc ttcttttacg
    10321 gccttttcag atccgtattt cactagatct tcatatgaca tggttactgc acgaataaag
    10381 cctttttcaa agtctgagtg gataatacca gctgcttgag gagccttcat accacgtttg
    10441 aaagtccaag cgcgaacttc tttttcacca gctgtgaagt aagttcccaa tccaagcaag
    10501 tggtaagctg cacgcgtcaa cttatctaca cctgattctg tcaaaccaat tgcttcaaga
    10561 aactcttttt tatcttcatc atccaattca gaaatttctt cctcagcacg cgcagaaata
    10621 acgactactt cagcattttc tgtcgctgca aattcacgaa tttgtttgac atagtcgata
    10681 gagtcaggtt ctgaaaccac atcctcgtcc acattagcta cataaagaac tggtttagtc
    10741 gtcaaaagga aaagaccttt gacaaccttt tgttcctcat ctgtaaattc aatggtacga
    10801 gctgatttcc cgtcttctag gactggttta atcttttgaa gaacattgaa ttctgctact
    10861 gattctttat ctttttgcgt acgtgccatc ttttctacac gcgcatatcg tttgttcact
    10921 gattctaagt cagcaagaat taattccaga ttaattgtat caatatctgc aagtggatct
    10981 acaaaggcgt cttcacgtcc ttgctcgcgc atcacatttt catcatcaaa agcacgaact
    11041 acgtgaacaa tcgcatctac ttcacgaata ttggccaaga atttattccc tagcccttct
    11101 ccttttgaag ctccttttac aatccctgca atatccgtaa attcaaatgt tgtgggaact
    11161 gtctttttag gagttatcat ttcagttagt ttttgtaggc gttcatctgg aacttccacc
    11221 attccaacat ttggatcaat agtcgcaaat gggtagtttg ctgcctctgc tcctgctttt
    11281 gtaattgcat taaatagtgt tgatttacca acgtttggca aaccaacgat acctgctgtc
    11341 aaagccatat ttctcattct ccgttttcat ttcaatccct aatattataa cacaaaaaga
    11401 gataaagtgc taaccctcta actaagggtt ctcagtcaat aattttattt atttttcgct
    11461 caaaatcata tcgccccatc atgacaacat gctcacaatt actgcatttt attttgatat
    11521 ctgctcctac acgtgtaatt tcccaacgat tagccttttt accagtcgac ttgattgtac
    11581 aagcgtgtgg ttttttcatc tcaacaaaat ttccaacttg atacatacta ctctcctttt
    11641 ctttttcgat tatatcataa aagaggcgag ccaggctcaa cctctttcac ttaatttgta
    11701 cgaactggtg taatgagctg catgaagtct tcgtcagtat ctgctggcac aagagtaaat
    11761 ggacgaacag ctgagataaa gctaatagtc accttttcgc tatttaaagc tttaagagaa
    11821 tcaatcaagt aagttgggtt gaaactaatg gtcaaatctt caccagtaac ctgatcagta
    11881 tcgatttctt cgtttacttt accaacttct ggagagtgaa catgggcgct aacaacccca
    11941 tccttaattt caagtttcac agtaccattt tgagtcgcac ttgataaaag acgggcacgc
    12001 tccattgact ggcgtaagtt taccacatta aaagtaatag tagtgttaaa gtctgttgga
    12061 atcaagcgat ctgtatcagg atagtttcct tctaggagac gagtatagaa gctaatattt
    12121 tcgcttctaa agaggatttg gttattggca aagaaaatct ctacagtttc gatatcatct
    12181 gtaaataccg ctgaaaattc gcgtagagaa cggctaggaa ttacgacatc aaaatcatca
    12241 ctattttttt caagagtcaa ttttttctgg cttaggcgat gagagtctgt tgcaactgtt
    12301 tttaactctt tgtgttgact caatacgaag tggacacctg ttaaaatcgg acgactctct
    12361 tgtgtacttg cagcaaaggc tgtttcatta ataattttct tgagtaattt tgtttcaagt
    12421 attaaaggag tgcttgctga aatttcttgg attcgtggat attgttcgct atcttttcct
    12481 tttagggtaa tttctgattt gccactggtt aaaacaattt gattttgttc aatttcttta
    12541 aaatcaagag ttacatcagg taaactagat actacattga taaagaaaga agcttcaaga
    12601 aggatcgaac ctaaagaagt aattaacaaa ccagcatctt catttttttg agaaataaaa
    12661 ttttcaattg aaatttgacc atttgaacca attaaagtaa taccttcatt ggtcacgtca
    12721 atttttactg ttgataaaat aggaatggca tttttagaac taatagctct cttagtagta
    12781 tttaatgctt gtagaaataa atttttatta attgaaaaat gaatcatgga ttctccttta
    12841 tttattttta gtattagaaa gataatagta ataatagagt ctgtgaaatc tgtggaaaac
    12901 agcctttaaa caagtcatat caagtttttt agcttgttta aaaaatgtgg ataaaaaaga
    12961 taaaaaacta aaagttatcc acaaattatt tgattttctt tttgattgat tcaatttcta
    13021 aacgtaaatt atcgtcttga tcaatcaaag attttatttt ggcatgggca tgaatgactg
    13081 tggtatgatc ttttccccca aattccttcc caatttttgg aagactatta tctgttagtt
    13141 ctctagataa atacatggct acttgacggg ccaaaacaat attttgaagg cgtctacttc
    13201 ccttcatttc tttgatacta acaccataaa agttaccaac ttcagtttgg attttatcaa
    13261 ttgggatgac gagcatttgg ctaacatctt gtttgcgggc tctaatggct tctgcagcaa
    13321 tatcaatagt gatatccttg atttttttta ctctggcaat taaagtgatg tcgttgatgg
    13381 ctccctcaag atctcgaaca tttgaatcaa attgcccagc taggtattct agagtatcac
    13441 tttggaaatt gtagcctaaa tgttccgttt tactttgtaa aatggcaata cgtgtttcaa
    13501 agtcaggggg tgtgatagtt tgtgtcaatc cccaactaaa acgcgtgaca agcctctcct
    13561 cgagcccttc tagatgtttt ggactacgat cactcgttag gacaatctgt ttttgcttgt
    13621 catgaagggc gttaaaggta ttgaaaaatt cttcctgagt tgcgactttt tttccgctga
    13681 gtgactggat atcatcgatt aacaaaagat caagactacg ataggtcttt ttaaactttt
    13741 ccatttcccc aagtcttagg tgatcaagaa agtcattaat aaagctttcg gcagggatat
    13801 atttaacacg cgcattagga atatttttta gaatttcatt tccaatagcg tttaataagt
    13861 gagtcttacc aaggcctggt cctccataga taaaaagagg gttataggtc agagccaaat
    13921 cttcagagac agctaaagcg gctgacacag cccaaacatt tccatcccct tgaataaagt
    13981 tatcaaaggt atacttttct tttaatcccg tatctgaata aggaatagat actaactttg
    14041 gactatagtt ataaagagtt aaatttgtag cttcttcaac ttgtgagcta gtcgtatctt
    14101 gaggtttggt gaaaatatag tggggagtta tttcagcgtc ataaatttca aaaccagcta
    14161 ctacaataat atcttttagt tgtttttccc agaccatttc catttcagag cgaggtagaa
    14221 atatagtggc aacattttcc tctaccttga tgagttcagc ttgaatagca tagaaatcat
    14281 acatggatcg agtcagtctt tcttgtgcaa attctaatat acgattccaa aattgttttt
    14341 ctttcaatcc tttctcctcc tttactattt aaaagtttaa tactagagat attttaccat
    14401 agatagcaag aattttccac aagctgtgaa aaataatcca caatgttacc aaactttatc
    14461 cacaggttgg ggataaaaga agaaattatt gatttattaa gctttttatt gaaaaacata
    14521 gtggataacc ttgtgagata aaaaaataaa agaacagcct tatttcaggc tgttgataat
    14581 tctactatat tcttcttgat ttgaaaaaga aataatgatt tttccactgt cttttttaga
    14641 tagtttaatt tctacatcta atccgagtag ttttcttaac tgtttttctt cattttgtat
    14701 gaaatgatta gttttttgct gtttcttttg ttttttctct gtcagaagag cttctaattt
    14761 ccttacagaa atatcttctt ctataatccg ttgaaagaaa tagtcttgtt gttccttatt
    14821 taacccaact agggaacgcg catgggcttg tgatagtttg ccattttcta cttctgaaag
    14881 aatctgttct ggcaaggaaa gtaaacgaat ggagttgctg atatatggac gagacttgcc
    14941 catcttatct gcaatttcag catgggtgaa tcctttctct acgagagatt cataggcgcg
    15001 tgcttcttct attgggttta aattttctct ctgtaaattt tcaataatgg actggaccat
    15061 catctcttgg tctgaaatct gtttaacaac agctgggata gaccgtagac cagctaaaag
    15121 tgaagcccga tagcgtctct ctcctgcaag gatttcataa ccaataacag gagattgacg
    15181 aacaataatc ggttgaatga ccccattttc tttgatagac tgtgctagtt catctagttt
    15241 ttctctatca aattcttttc ggggttgata gggatttttt tgtatatctg tgatagaaat
    15301 catttcaaat ttttccatga ttctacacta acacatcttt tctcttatgt aaagctttct
    15361 ttacatagat gtcaattaag attctaaatc accagaactc ttgttaagtt tgatagaggt
    15421 agtttcttct ttcccgttac gatagtaggt tatcttaatg gtgtctccga tagaatggtt
    15481 gtaaagagca ctttgtaagt ctgttgatga agcaatctct ttgtcatcta cttttgtaat
    15541 tacatcgtat ttttcaaggt gaccattggc aggcatatta ctttgtaccg aacgaacaac
    15601 tacaccagat gtaacattac ttggaatatt gagtcttctg atgtcgcttg tactcacatt
    15661 agataaatta accatctgga ttcccaaagc tggacgcgtc acttttccgt ttttttctaa
    15721 ctgttcaata atattgatag catcatttgc aggaattgcg aaaccaagac cttctacaga
    15781 tgttcctcca tttgtagcaa ttttacttga ggtaattccg ataacctgcc cttgaatatt
    15841 gatcagtggg ccgccagagt tacctgggtt aatagcagta tcagtttgga tggcttttgt
    15901 agaaatagct tgtccatctt ccgattttaa ggatacattt ctattgagac tggatacgat
    15961 accttgagtg actgtatttg catattcaga acctaacggg ctaccgatgg caatagcagt
    16021 ttctcctaca gttaacttac tagaatcacc aaactcagct actgttgtca ctttttctga
    16081 agagattttt acgacagcaa tatcagagaa agtgtcagct ccgacaattt ctccaggtac
    16141 tttagtccca tctgacaatc gaatatctac tttgctggcg ccatttataa cgtgattgtt
    16201 ggtgacgatg taagcttctt tatcattctt tttataaata actccagatc cttcactaga
    16261 gattcgctga gaatctgtgt cagtatcatc attgccaaat acgctatttt gtctgtttgc
    16321 cgaataagta ataacagaaa caacagcatc ttttactttg ttaacagcct gtgttgttga
    16381 attttcgttc ttataggcag tttgtgtaat agtactattg ttgttagagt tgtttacact
    16441 acttttttga gttagttgag ttattgaaaa actacccaag gctccactaa aaaagctaat
    16501 gacgataacg actaataatt gaaaccattt tttgtaaaat gtttttagat gtttcatatt
    16561 tgcctccata tgtttgaatt actgaaagta taaactgact agcttaatta taacttaaac
    16621 acaaaagttt tacacaaact gtggataact cttttgaaac tgtgattttc ttaattgaaa
    16681 tctatttttt attttgtgaa taagatgtga aaaaatagag aatatgttag aatagagtca
    16741 tgaaaattaa agttgtaaca gttgggaaac tgaaagaaaa gtatttaaaa gatggtatcg
    16801 cagagtattc aaaacgaatt tctagatttg ctaagtttga aatgattgag ttatcagatg
    16861 aaaaaacacc agataaggcc agtgaatcag aaaatcaaaa gattttagaa atagaaggtc
    16921 agagaatttt atcaaaaatt gctgaccgtg atttcgttat tgtgttagcc attgaaggga
    16981 aaactttctt ctcagaagaa tttagtaagc agttagaaga aacttctata aaaggatttt
    17041 ctactcttac ttttattatt gggggaagtt taggattgtc atcatctgta aaaaatagag
    17101 ccaatctttc tgtcagtttt ggtcgcctaa ccttacccca tcagttaatg agactagttc
    17161 ttgttgaaca aatctatcgc gcttttacga ttcagcaggg attcccctac cataaataga
    17221 aaattgactt ttaattgaat ttttggtaga ataattgtat taggtctcat agctcagctg
    17281 gatagagcat tcgccttcta agcgaacggt cgcaggttcg aatcctgctg ggatcaatat
    17341 aatagcaaag ctgggaattt tcccggcttt tttcttaaaa aagtacactt tgggagaaaa
    17401 aaatgacagt tgagagaatt ttatctaaaa cgaaattcca ttttgtataa tggtttttgt
    17461 aagttagctt acaagaaaaa acattttagg agattttatt atgaaaaaca cagttaaatt
    17521 ggaacagttt gtagctttga aggaaaaaga cttacaaaag attaaaggtg gggagatgag
    17581 gttgtcaaaa ttcttccgtg attttatttt acaaagaaaa aagtaatgaa ataaggggaa
    17641 agagtaatgg atttatttgg atttgggacg gttattgttc attttttaat tattagtcac
    17701 agttaccatt ttatttgtaa aggtcaaata aatagaaaag aattattcgt ttttggtgct
    17761 tatacattac taacagaaat agtatttgat tttcccttat atattctata tttagatggg
    17821 ttagggattg aaagattttt atttcctttg ggattatatt cctattttcg atggatgaaa
    17881 cagtatgaga gggatagagg actattccta agtttactac tatctctttt atatgagagc
    17941 actcataact ttctgtccgt aactttctcc tctataacag gagataattt tgttttacaa
    18001 tatcatttcc cattcttttt cgttgtgacg gtgttaacct attttgttac attaaaaatc
    18061 atttactatt tccatttgga actagcctat tttgacgagg actaccttta tcctttcttg
    18121 aaaaaagtat tttttgcttt actattgcta catattgtat ctttcgtttc agatatggta
    18181 agtacgatta aacatttgaa tagttttgga agtattttgt catctattgt ctttatctct
    18241 ctccttttga ccttctttgc aatgaattct cataaagttc aaatggagaa agagattgct
    18301 ttgaagcaga agaaatttga acagaaacat ttacagaatt acacagatga aattgttggt
    18361 ctgtataatg aaatccgtgg ttttcgacat gattatgctg gaatgcttgt cagcatgcag
    18421 atggcaattg acagtggtaa tttacaggaa attgacagaa tttacaatga agttttagtc
    18481 aaagcaaatc ataaattgcg ttcagataag tacacttact ttgatttgaa caacatagaa
    18541 gactcagctt tacgaagttt ggttgctcag tcaattgtct atgctcgaaa taatggtgta
    18601 gagtttacac tggaagtaaa agatacgatt accaagcttc caattgaact attggatttg
    18661 gttcgtatca tgagcgtttt attgaataat gctgtcgaag gatcggctga tagctataaa
    18721 aagcagatgg aagtagcagt tattaagatg gaaactgaaa cagttattgt gattcagaat
    18781 tcatgtaaaa tgacgatgac tccttcagga gatctatttg ccttaggatt ctccactaag
    18841 ggaagaaatc gcggagtcgg attaaataat gtgaaagaac tactagataa gtacaacaat
    18901 attattttag aaacagagat ggaaggcagt acatttagac aaatcattag atttaagagg
    18961 gaatttgaat gaaagtttta attttagaag atgttattga acatcaagtg agactagaga
    19021 gaatattgga tgaaatttcg aaagaatcga atattccaat atcatacaag acaacgggaa
    19081 aagtccgtga atttgaagaa tacattgaaa atgatgaagt aaatcagctt tatttcctag
    19141 atatcgatat tcatggaatt gagaaaaagg gatttgaagt ggctcagctc attcgtcatt
    19201 acaatcctta cgctattatc gtctttatca ctagtcgatc agagtttgcg actctaacct
    19261 ataaatacca ggtatcagcc ctagattttg ttgataagga tatcaatgat gagatgttta
    19321 agaagagaat tgagcaaaat atcttctaca cgaagagtat gttacttgaa aatgaagatg
    19381 ttgtagatta tttcgactac aattacaagg gaaatgattt aaaaattcct taccatgata
    19441 ttttgtatat tgaaacaaca ggggtctctc ataaattgcg cattattggt aagaattttg
    19501 caaaagagtt ttatggtacc atgacagata ttcaggaaaa ggacaaacat actcagcgat
    19561 tttattctcc tcacaagtca tttttggtaa atataggcaa tatcagagaa attgatcgaa
    19621 aaaacttaga aattgttttc tatgaagacc atcgttgtcc tatttcaaga ttaaaaatta
    19681 gaaaattaaa agatatttta gagaaaaaat ctcaaaagtg attgacaatt agcaagaaat
    19741 tgatataatg gttatatctg ctacagatag aaggtccgtt ggtcaagggg ttaagacacc
    19801 gccttttcac ggcggtaaca cgggttcgaa tcccgtacgg actattttat ccgccatagc
    19861 tcagttggta gtagcgcatg actgttaatc atgatgtcgt aggttcgagt cctactggcg
    19921 gagtatagat aaaagggaac acagctgtgt tcctcttttt gtatcaattt gtatcaccaa
    19981 gcattttcat aaggaagtct gttatttctt gagaactttc tttttttcca tgtgcaatcc
    20041 aagtttggca gacaccaaaa agtgcatgag ttagatagat gctactatat tctaattcgg
    20101 tggtatttag attcagttgc ataaatcgct tttgtaaatc tgtactaagc atgatatgaa
    20161 gtttatttcg taagaaattt tggatttctt tagtcccatt ttcagaaaga agggcagcca
    20221 gaagtggttc tgactctaga tattcaaaaa cttctaaaat agcgtctctt ttgtgatgag
    20281 catgtttttg aaaaatatat tcaaatgtat ggaatagctt gctttgatag tgctcaatca
    20341 tatcatactt atccttatag tgagtataga agctggaacg actaattccg gctttttcta
    20401 ctaatttgac agtagaaatt ttatcaaatg gctgttccat cagtaattgt accatagcat
    20461 tttcaatagt tcgctttgtt tttaagcgtt tgttactttc ttgcatattt cctccttgta
    20521 aacaaattag actatatgtc taaaaataga ttttttatct tgtaatttag attttttaat
    20581 gtataatcta ttatatcaaa attttagaca atatgtttaa aaaaggagaa actaagttta
    20641 aagaatggaa agcaatttaa aaaaaaccaa cctttattat tgtcatgatc gggatttctc
    20701 ttattccaga tctgtacaat atcatatttt tgtcatcaat gtgggatcca tatgggcaat
    20761 tgtctgactt acctgtggca gttgtaaata atgataaaga ggcttcctat aatggtaata
    20821 ctatggcaat aggaaaagac atggtgtcca atttaaaaga aaataaaacc ttggattttc
    20881 attttgtaga tgaagaggaa ggaaagaagg gattggaaga tggcgattac tatatggtag
    20941 tgactttacc aagtgattta tctgaaaaaa caactacatt atccaatatt caatcgacag
    21001 cagcttatca atcattgaca agtgagcaac aaactgagat aagtgattct gtatctcaaa
    21061 attcaactga tagtattcaa tcggctcagt caattgtagc tttagtacaa gatttacagg
    21121 gaagtttaga aaacttacaa aatcaatctt ctaatctttc gactttaaaa aatcaatcta
    21181 atcaagtatc acctattact tctacttctt tgataggatt gtcaagtgga ttaacagaga
    21241 tacaaggaga tgttactagc aaattagttc ctgccagtca gtcgattgca tcaggtgtaa
    21301 acgcatatac tacaggtgtt gataaagttt ctcagggcgc aagtcaacta agtgaaaaaa
    21361 atgccacctt gacaggtagt ttgaataaac tagtttcagg ctcaaacacc ttgacacaaa
    21421 aatcttctag attgacagca ggagttggtt aattacaatc aggatctggg caattagcag
    21481 acaaatccag tcagttactt tcaggtgctt ctccattaga gaatagagct aataaattgg
    21541 cagatggatc tgggaaacta gcagaaggtg gaacaaagtt aacttctgga ttggaagatt
    21601 tacagacagg acttgcttct ttaggacaag gactaggtaa tgctagtgat caactcaaat
    21661 cagtatcaac agaatctaaa aatgcagaga ttttgtcaaa tccactcaat ctttcaaaaa
    21721 cagacaatga tcaagttcct gtaaatggaa tcgcaatagc tccttatatg atatcagttg
    21781 ctcttttttt tgcagcaata tcaacaaata tgatatttgc gaaattgcct tcaggacgtc
    21841 atccagagag ccgttgggct tggttgaaat cttgagctga aataaatggt attatagctg
    21901 ttttggcagg aattttggta tatggaggag ttcagcttat tggtttaact gctaatcatg
    21961 agatgagaat atttattctc atcatcctaa caagtttagt attcatgtct atggtgacca
    22021 ctttagcaac gtggaatagc cgtataggag cttttttctc acttattttg cttttactac
    22081 agttagcatc aagtgcaggt acttatccac ttgctttgac aaatgatttc tttagatcta
    22141 ttaatccctg gttaccaatg agctattcag tttcgggatt acgacaaaca atctctatca
    22201 acaagtcatt ttcctagctg tcatactagc tctatttact ggtttaggta tgctagccta
    22261 tcaacataag aaaatggaag aagattaaaa aaatcgaccg attaactggt cgatttttta
    22321 tgccttagat gactttcgtc tgtgattata gattccaaat agtaagagag aagtaaagga
    22381 acagattgct ccagtaataa aaccattggg aatgaaggaa agtgtaatag ttcctttccc
    22441 cttgggaatg tcaactttca taaatccagt ttgagcttgt ttaatttcta ttttcttacc
    22501 atcttggtag gcagaccaac ctttgtcata aggaatggtg aagaaaatag atgtatcttg
    22561 ttggacatca tatgtagcaa aaaccttgtt tttagaagtt gatactgtga caggttgttc
    22621 tttaattttt tgaattgcct cggtgaaagt tttggtatct aaacgataga aggtaggaga
    22681 ttcaaatgat acttgtgaat ttccagggaa actaacattg atattgaaag tttttttctc
    22741 tttagtatat cctagattaa agaaggagaa gacattatca gttgtaaaag tctttttttc
    22801 accatttaca aggatgtcaa ccttcttttg tttatcgtta gaaaagtgaa ggtttatgaa
    22861 agagagataa acttggctgt tttctggaac ttcaatttga tactggattg ctgcatcttc
    22921 atttgaagaa cttgtgacac taatcaaatc attagtattt tctatttttt ctgttttttc
    22981 ataaggtatt ggagaaaaat aatcaaaatt gacgttagca agttgattta aaaatgaggc
    23041 ctgattatcc aaggtatgtt cattgaactt gacatcattg taaacagatt gactagcaac
    23101 tgcaatcgga agagagtatt gattttcata tagggtaaga ttatcttttt gatagatatc
    23161 tttaaagcca tacttatcaa taggactgtc tgagatattg tactggatac caaataaact
    23221 atcagccaaa atactattat ttgcatatcg gagattgaga ttagtcccag aggatttaaa
    23281 accaagttta tctaaagtag agcttgatga acgatttcga acagatgaaa attgagagat
    23341 tccattgtag ttgaatttca tactgtcatt tcctgtctga gtttgtagtt tttcagtacg
    23401 agtaaattga tttccaatat atgttgagaa agattccata gctgggatat ctcgactata
    23461 agcacttcga gaagcaaatc cccattcctt agcaattccg tccatttgag atgaagcatt
    23521 taaactcatt tcaaccagta taaataaaga gattagaatg gcaaatagat tcacagatat
    23581 aaactttttg ataactgcaa ggagtaaaag agaatagaca accaaaaatt caagagtaag
    23641 cagaatattc aaatctgtta aaaaagaata atgcgatttt agatagatgg tagctaaaaa
    23701 tcctgttact acaagaaaaa gcgaaactaa aaaattccag actttaagtt ctttcagacg
    23761 ctttaagact tctgctgctg tgtaaattaa caaggtagag aaaatccaag catagcgatg
    23821 taaaaacatg tttggagtat gcatgccttg ccaaaataag tcaagagctt ctatgtaaaa
    23881 gcttgcaatt agaaatgcaa agaatattat atatatgagt ttcacgtgaa acttaataga
    23941 tttcagcgta aaaaataaaa tggtcaaaat aaagggaagt agtccaacaa aaatcattgg
    24001 gatggcccca tactttgttg tgtcaaagga accaatgaat tgcttagcaa agagatcaag
    24061 ataccagcta ctttcagttt gaaactttgt aacttcagtc aatttttccc catgtgtctg
    24121 taaatcaaac agagtgggaa gagtcataat caaactagcc ataccagcta aaaaggagat
    24181 aactatgaaa tcaagaacag atgattttcg agtcttaaag tcccacgaaa tttgacagag
    24241 ataccagaaa ataagaaaca atactgtcat atatccaaaa taataatttt gaataaataa
    24301 gattgacaga cttgtaaagt acaataggag tttcttttca gttatcagta gatgtaaacc
    24361 agttataatt aaaggaatca agataaaaac atctagccag gtttttatct ctaattgact
    24421 gacagtgaaa ctcatcagag cataggaagt agataaggct agctttaaag tctgagggat
    24481 agattgaaac aatttattca aactaaaaaa ggttgacaga ccaatcaatc caaattttaa
    24541 gagagtggtc agatagacag catctggcat attcgttaga tcaaaaaagt aaactagagg
    24601 cgcgagaaaa ctacccaagt aataactaga tagggcatag aagtttagcc ctagaccact
    24661 tgtaaaggtg taaaacagac tactatttcc atgtaggata tttcgtaagg ctacatcaaa
    24721 aataacgtat tgatgaaagc catctcctaa tagaggagag ttgtcgctat tccagtagat
    24781 accttgagat agatatactc cagacataat cactacagga atgatgaaag aaataaaata
    24841 ggttcgatat gtttttaaaa atgatttcat gttacctcgt agaatgatag aaaactcagt
    24901 tggttaaccc aactgagttt tgaagtttta tttagtcttt ccaaagttct ttaacttttg
    24961 cttgtacttc tgcattttct aggaattcat cgtaggtttc atcgatacgg tcaatgacgc
    25021 catttttaga taagacaatg atatggttag ccaaagtttg aataaattcg tggtcatggc
    25081 tagcaaagat gattgattct ttaaagtttt tcaatccatc attcaagctt gagatagatt
    25141 ccaagtccaa gtgatttgtt ggatcatcaa gtacaaggac atttgatttt aagagcatga
    25201 gttttgaaag catgacacga actttttctc cccctgacaa gacatttaca ggtttgttaa
    25261 cttcatctcc agagaagagc atacggccga ggaaaccacg taggaaagta ttgtcatctt
    25321 cttctttact tgcgaattga cgcaaccagt caagaattga ttctcctcct gcaaaatcag
    25381 ctgagttatc ttttggtagg taagattgac tagttgtaac tccccacttg acagttcctt
    25441 catagtcaat atctcccatg attgcacgaa ttaatgcagt tgtttgaata tcattttgtc
    25501 caataagtgc tgtcttatca tctggacgca agatgaaact aatattatcc aagatagttt
    25561 caccatcaat ctttacagtt agattttcta ctgtcaagag atcattacca atctcacgtt
    25621 ccgctttaaa gttgataaat ggatatttac gactagatgg tacaatctct tctagctcaa
    25681 tcttatcaag cattttctta cgtgatgttg cctgccttga cttagaagca ttggcagaga
    25741 aacgagcaac gaattcttgc aattgtttaa ttttttcttc tgctttagca ttacggtctg
    25801 ctagcaattt agcagcaagc tcagaagatt ccttccagaa gtcgtagttt ccgacataga
    25861 gtttgatttt tccaaagtca aggtcggcca tgtgagtaca aactttgttt aagaagtgac
    25921 ggtcgtggga tactacgata actgtgttat caaagtcaat caagaagtct tctaaccaag
    25981 taatcgattg gatatccaaa ccgttagtag gctcgtccaa gagaagaaca tctggtttac
    26041 caaaaagtgc tttggcgagg agaaccttta ctttttcacc gttggccaat tcgctcatgt
    26101 tttggtagtg taattcttct ggaatgttta ggttttgaag tagttgagag gcttcactct
    26161 ctgcttccca acctccaagt tcggcaaact ctccttcgag ttcggcagca cgaaccccgt
    26221 cctcgtctga gaaatcttcc ttcatgtaga tagcatcttt ctctttcatg atgctataaa
    26281 gtttttcatt tcccatgata acgacatcaa tggcacgttc atcttcgtag tcaaagtgat
    26341 tttgacgaag aacagagaga cgttcatctg gaccaagaga gatgtgacca gtagtaggtt
    26401 cgatatctcc agctaaaatt tttaaaaagg ttgattttcc ggcaccatta gcaccgatta
    26461 atccgtaagt atttccttct gtaaatttga tattgacatc atcaaaaagt ttgcgatcac
    26521 taaaacgtag tgaaacatca gatactgtaa gcaatatttt tctcctatat gtgtaatata
    26581 tttattctac tagaaaatac agaaatattc aaatttttat ttgtcaattt tgtgtaaatt
    26641 atatttacag tatcctttac acaaatctgt aaaaagcaag gctgatttat tttgataaat
    26701 tacggttatt tcattaaaaa aatgctataa ttgaaaggac tatatcgaag gagaacaaaa
    26761 tgactaaacc cattatttta acaggagacc gtccaacagg aaaattgcat attggacatt
    26821 atgttggaag tctcaaaaat cgagtattat tacaggaaga ggataagtat gatatgtttg
    26881 tgttcttggc tgaccaacaa gccttgacag atcatgccaa agatcctcaa accattgtag
    26941 agtctatcgg aaatgtggct ttggattatc ttgcagttgg attggatcca aataagtcaa
    27001 ctatttttat tcaaagccag attccagagt tggctgagtt gtctatgtat tatatgaatc
    27061 tagtttcgtt agcacgtttg gagcgaaatc caacagtcaa gacagagatt tctcagaaag
    27121 gatttggaga aagcattccg acaggattct tggtctatcc aatcgctcaa gcagctgata
    27181 tcacagcttt caaggctaat tatgttcctg ttgggacaga tcagaaacca atgattgagc
    27241 aaactcgtga aattgttcgt tcttttaaca atgcatataa ctgtgatgtc ttggtagagc
    27301 cggaaggtat ttatccagaa aatgagagag cagggcgttt gcctggttta gatggaaatg
    27361 ctaaaatgtc taaatcacta aataatggta tttatttagc tgatgatgcg gatactttgc
    27421 gtaaaaaagt aatgagtatg tatacagatc cagatcatat ccgcgttgag gatccaggta
    27481 agattgaggg aaatatggtt ttccattatc tagatgtttt tggtcgtcca gaagatgctc
    27541 aagaaattgc tgatatgaaa gaacgttatc aacgaggtgg tcttggtgat gtgaagacca
    27601 agcgttatct acttgaaata ttagaacgtg aactgggtcc tattcgtgag cgccgtattg
    27661 aatttgctaa ggatatggga gaagtttata atatgattca aaaaggtagt gaaagagcgc
    27721 gtgaagttgc gggtcaaacc ctatctgagg taaaaggggc aatgggactt cattacttta
    27781 actaagttta ttttacaaga aactatcatt tctatctcga agaaaagata gttttttatt
    27841 tacccctgta acatttgaca aatttttata gaatggtatg atagatacaa tataaaaaga
    27901 gtcaagctca aaaagaaaga aaagaggaaa cttcgaatgt ctaattggga cactaaattt
    27961 ttgaaaaaag gttttacctt tgatgatgta ttgcttattc cagctgaaag tcatgtgttg
    28021 cctaacgatg cagatttaac aactaaattg gcagataatt tgactttaaa tatcccaatt
    28081 attaccgctg ccatggacac agttacagag agtcaaatgg ccattgctat tgctcgtgca
    28141 ggtggtctcg gagttatcca taaaaacatg tcaattgctc aacaagcaga cgaggttcgt
    28201 aaggtaaaac gttctgaaaa tggagttatt attgatccgt tcttcttgac gcctgaacat
    28261 acaattgctg aagcagatga gcttatgggt cgttaccgca tcagtggtgt tccagttgtt
    28321 gaaacacttg aaaatcgtaa attggttggt attttgacaa accgagatct tcgttttatt
    28381 tcagattata atcaaccaat ttcaaaccat atgactagtg aaaatcttgt tactgctcct
    28441 gtgggtacgg atcttgcaac ggctgagagt attcttcaag agcatcgtat tgaaaaactt
    28501 ccgttggtcg atgaagaagg cagtctttct ggtttgatca ctatcaaaga tattgaaaaa
    28561 gttattgagt ttccaaatgc ggctaaagat gagtttggtc gtcttctagt tgcaggtgca
    28621 gtaggtgtta cttcagatac atttgaacgt gcagaggctc tttttgaggc aggagcggat
    28681 gcgattgtta ttgatactgc acatggtcat tctgcaggtg tcttgcgtaa aattgccgag
    28741 attcgtgctc atttcccaga tcggactttg attgctggaa atattgctac tgctgaaggt
    28801 gcacgtgccc tttatgaagc gggtgtagac gttgttaagg ttggtattgg accaggttct
    28861 atctgtacta ctcgtgtgat tgctggtgtt ggtgttccgc aagtaacagc tatctacgat
    28921 gctgcagctg ttgcgcgcga atatggtaaa acgattattg ctgacggtgg gatcaagtat
    28981 tctggagata ttgtaaaagc acttgctgca ggtggaaatg ctgttatgct tggatctatg
    29041 tttgctggaa ctgatgaagc tccaggcgaa actgaaatct tccaaggacg taaattcaag
    29101 acttaccgtg gtatgggatc aattgctgct atgaagaaag gttcaagcga ccgttatttc
    29161 caaggttctg tcaatgaagc aaacaagctt gttccagaag gaattgaagg tcgtgttgct
    29221 tataaaggag cggcagctga tattgttttc caaatgattg gtggtattcg ctctggtatg
    29281 ggttactgtg gtgcagctaa ccttaaagaa ctacacgata atgctcaatt tattgaaatg
    29341 tctggtgctg gtttgaaaga aagccatcct catgatgtgc aaattactaa tgaggcacca
    29401 aattattcta tgtaaaaaac aatgaaaaga actccagtga aaacaggagt tcttttacaa
    29461 tgttgtcaat ttccatttac agcagcttta ccatcctgaa tagtgaagat acttagattt
    29521 tctggcagat tttgaagatg gtctaagctt gttgttgtga taaaggtttg gattgattga
    29581 gaaatcgttt ctaataattt taactgtcta gtgttgtcaa gttcactcat cacatcgtca
    29641 agcagtaata tcggagattc tgtggtaatg ctttccatta attcgatttc tgctaatttt
    29701 atcgagagga cgagactacg atgttgacct tggcttccga aactagcatc catcccattt
    29761 atataaaaag aaatgtcatc tcgatgagga ccgacaccag tattcttttt aaataaatct
    29821 ctggatctac ttttttctaa agcaattttg aaagattcgg ataagttttg tttgtcagtt
    29881 gtattgacag aagattgata ggatattgac aactcttcga tctgattaga gagttcaaaa
    29941 tgtttcttac gcccaaatga ttctagtttt tttatgaaat ctaagcggtg attcattaca
    30001 cgacatccat aatcaactag ctgatcatct aacacagaaa ggaatgtttc atctattttt
    30061 tgaactgatt ttaggtaagt gtttctttgc tttaggatgt ggttataatt ggttaagtca
    30121 gataaataga ttggcttaat ttgcccaagc tccatatcaa tgaattttcg tcgaatcgaa
    30181 ggtgctcctt taattagttg taaatcttca ggagcaaata agacaacatt catgtgtcct
    30241 acataatctg aaaggcgtgc ctgttttaag tgattaactt ttgttacacg gcctttttgt
    30301 gttagttcga tttctagggg aatggatcca gtttttttct gaacgagacc tgaaagatga
    30361 agttgttcct catcaaaatg aatgagattt ttatctgttc gagttcgatg actacgcgtt
    30421 aaggctaaaa aatagatagc ctctaacatg tttgtttttc cttgtgcatt acgtcccaaa
    30481 aagacattca atttaggatt aaagtctatt ttcgtttctt tgtaattacg aaaagtcttg
    30541 agagatagat gttgtagcca catgattatc taccagggaa tcgtggagct tgttggcttt
    30601 taggtgatga agcaggtttc gatttgtctt ttttaactcc cttattcatc tttttgacaa
    30661 gtttagcgat ccgttctttt tcaactttat cagcttggta ttcatcttgt tcttcagaag
    30721 taggttgtgt caacaagatg tcaatgttca tgtcagggat gtcaacttta tcgccaatac
    30781 gaagtttttt tccacgacga ctctctaatt ccctattaaa gtaaacagaa tgttcagaga
    30841 gaaatgattt aatagctcct ccgctatgtg taattccaag ttctttgagt agtgcttgga
    30901 gggtaataaa ttcttcaaat aatttgtatt ccataattca cctcaatctt tggtattata
    30961 ccatattttc ctaaaaatag tgagagagat agctagaaat gtaagcgatt tttatttcaa
    31021 aagtgttaca gggaacaaga aaatttcagg ttttcgtgat ataatagaag tctgtatata
    31081 aggaggtaaa tcatggagtt agtgcatgga atttcaacac attttatcca atcaaaaaag
    31141 tttaaaacaa acaaaattac cgtgcgtttt accgctccat tatcccttga tacgattgca
    31201 ggtcacatgt tgagtgcaag tatgctagag actgctaatc agatgtaccc cacttctcaa
    31261 gatttgagga gacacttggc cagtctatac ggtacagata tgtcaaccaa ttgtttcaga
    31321 agagggcaaa gccacattat agaattgaca tttacctatg ttcgtgatga gtttttaagt
    31381 aggaaaaacg tgctaacctc tcagattttg gaacttgtaa aagaaactct tttttcaccc
    31441 gcagtagttg ataatgggtt tgatccggcc ttatttgaaa ttgagaaaaa acaattgcta
    31501 gcaagtttag cagctgatat ggatgattct ttttattttg cacataaaga attggataaa
    31561 ttgttttttc atgatgaacg tcttcaattg gaatatagtg atttacgaaa tcgtatttta
    31621 gctgaaactc cacaaagttc ttattcttgt ttccaagaat ttttagccaa tgatcgaata
    31681 gatttctttt tcctaggtga ttttaatgag gttgaaattc aaaatgtatt agaatcattt
    31741 ggctttaaag gtcgaaaagg agatgtgaag gttcagtatt gtcaacctta ttctaatatc
    31801 cttcaggaag gtatggttcg gaaaaatgtg ggacaatcca ttttggaatt aggttatcat
    31861 taccgttcta aatatggtga tgaacaacat ttacccatga ttgtaatgaa tggtttactt
    31921 ggtggatttg ctcactctaa gctctttaca aatgtccgtg aaaatgctgg attagcttat
    31981 accatttcaa gtgagcttga tttatttagt ggattcttga ggatgtatgc tggtatcaat
    32041 cgagaaaatc gtaaccaggc tcgtaaaatg atgaataatc aactgcttga tttaaaaaaa
    32101 ggttatttta cagagtttga gttaaatcag accaaggaaa tgattcgttg gtcgttgtta
    32161 ctttctcaag ataatcaatc ttcattgatt gaacgtgctt atcaaaatgc cttatttgga
    32221 aaatcttcag cagactttaa aggttggatt gcaaaactcg agcaagttga caaagatgct
    32281 atttgtagag cagctaataa tgtgaaacta caggcgattt actttatgga aggaatagaa
    32341 tgacaaaggt tgtttttgaa aaaaaatact atccagctgt aaaagaaatg atttatcgaa
    32401 ctcgtttggc caacggattg acagttgctc ttttgcctaa aaaggaattt aaagaggttt
    32461 acgggagtgt cactgtacag tttggttcgg tagatacgtt tgtcacagaa gttgacggag
    32521 atgtaaaaca atatcctgca ggaattgctc attttcttga acataaatta tttgagagag
    32581 aagattctag tgatttgatg tcggctttta cgagtctagg tgcagatagt aatgccttta
    32641 caagctttac aaaaacaaac tatctttttt cagcaacgga ttatttttta gaaaatttat
    32701 atttacttga tgaattggta acatcagcac actttactga agcttccatt ctgacagagc
    32761 aggatattat tcagcaagaa cgagaaatgt accaagatga tccagattcg tgtttattct
    32821 tttcaacttt agcgaatttg tatcctggta cacctttagc aactgatata gttggaagtg
    32881 aggagtccat ttcccaaatc aatctaacta atttgcaaga aaattttaca aagttttaca
    32941 aacctgtaaa catgtctctg tttttagttg gtaattttga tgtggagcga gtacaggact
    33001 attttgaaag caaagaactg aaagattcag attttcagga agtagcaaga gaaaagttgt
    33061 ttttacagcc tgtaaagcca acagatagta tgagaatgga agtatcttct cccaaactag
    33121 cgattggagt tagaggtaag cgagaagttt ctgaagcgga ttgctatcga catcatattt
    33181 tattaaaatt attgtttgca atgatgttta gttggacttc ggatcgtttt caaaaatgtt
    33241 atgaatcagg taaaattgat gcatccttat ctctggaagt tgaagtaaca agtcgctttc
    33301 attttgtcat gttgacaatg gatacgaaag agccagttgc tttgtctcat caatttagga
    33361 aggctattcg taattttaca aaggatttag atattacaga ggaacattta gatattatca
    33421 aaagagagat gtttggcgaa tttttcagta gcatgaactc tcttgaattt attgcaacgc
    33481 aatatgatgc ttttgaaaat ggtgagacaa tttttgattt gccgaaaatt ttacaggaaa
    33541 ttactttaga ggatgtcctt gatgctggac atcatttaat agatgatggt gacatagttg
    33601 attttacaat attcccatcg tagtaaccta ttataataga cactagaaag aagggatgac
    33661 aagtatgaga aaaaaaacaa ttggagaggt tttacgatta gctagaatca atcagggatt
    33721 gagtttagat gaattgcaga aaaagacaga aatccagtta gatatgttgg aagcaatgga
    33781 agcagacgat ttcgatcaac ttccaagtcc tttttacacg cgttctttct tgaaaaaata
    33841 tgcatgggct gttgagttag atgaccaaat tgttttggat gcttatgatt ctgggagtat
    33901 gattacttat gaggaagtag atgttgatga agatgagttg acaggtcgta gacgttcaag
    33961 taagaaaaag aagaaaaaaa catcattttt acctttattt tattttatcc tttttgcttt
    34021 atcgatttta atttttgtga cttattatgt ttggaactat attcaaactc aaccagagga
    34081 gccttctctt tctaattaca gtgtggttca atcaacaagt tcaactagct ctgttcccca
    34141 ctcctcaagt agtagttctt ctagtataga atcagctata agtgtatcag gcgaaggaaa
    34201 tcatgtagaa atcgcttata agacaagtaa ggaaacagtt aaattgcaat tggcagtttc
    34261 agatgttaca agttgggtca gtgtttcaga aagcgaactt gagggcggtg taaccttatc
    34321 gccaaagaag aaaagtgcag aagcaacagt tgcaactaaa agtcctgtaa caattacgtt
    34381 aggtgttgta aaaggtgttg atttgacagt agataatcag actgttgatt tatcgaaatt
    34441 aacagctcag actggacaaa tcactgtaac ctttactaaa aattaaggaa aaacgaatga
    34501 aaaaagaaca aattcccaat ctcttaacaa taggtcgaat tctctttata cctattttta
    34561 tctttatttt aacgatagga aattcgatag agagtcatat agttgcagct attatctttg
    34621 ctgttgccag tattaccgac tatttagatg gatatttagc tcgtaaatgg aatgtggtca
    34681 gtaattttgg taaatttgca gatcctatgg cggataagtt actagttatg tcggctttta
    34741 ttatgttgat tgagttaggt atggctccgg cttggattgt tgcagtgatt atctgtcgtg
    34801 agttagctgt gacaggttta aggcttttat tggttgaaac tggtggaaca attttagcag
    34861 cagcaatgcc tggaaaaatt aaaactttta gtcagatgtt tgccattatt ttcttgctat
    34921 tacattggac tttgcttggt caagttctac tttatgtagc cttatttttc actatctact
    34981 ctggctatga ctatttcaag ggtagtgcct atgtatttaa agggacattt ggttcgaaat
    35041 gaaatcaata attgatgtaa aaaatctttc ttttcgctat aaagaaaatc agaactacta
    35101 cgatgtgaag gatattacgt ttcacgtgaa acgtggagaa tggctttcga ttgtagggca
    35161 taatggtagt ggtaaatcaa cgacggttcg attaattgat ggcttactgg aagcagaatc
    35221 cggagagatt gtaattgatg gccaacgttt gactgaggaa aatgtttgga atatacgtcg
    35281 tcaaatcggt atggtttttc aaaatccaga caatcaattt gttggagcga ctgttgaaga
    35341 tgatgttgct tttggtttgg aaaatcaggg actttctcgt caagaaatga aaaagagagt
    35401 ggaagaagct ctggctttag ttggcatgtt ggactttaaa aagagagagc cagcgcgtct
    35461 atcaggtggt caaaagcaac gtgtggccat tgcaggtgtt gtagccctaa gaccagctat
    35521 tttaatctta gatgaagcaa cgagtatgtt ggatcctgag gggcgtagag aacttattgg
    35581 gacagtaaaa ggaattcgaa aagactatga tatgacggtc atttctatta cccatgattt
    35641 ggaagaagtc gccatgagtg atcgcgtatt ggtcatgaaa aaaggggaaa ttgaatcaac
    35701 tagtagtcca agggagcttt tctctcgaaa tgatttagat caaattggat tagacgatcc
    35761 ttttgctaat caattaaaaa aatctttgag ccagaatggc tatgatttac ctgaaaatta
    35821 tttgacagaa agtgagctag aggataagct atgggaattg ctctagaaaa tgtgaatttt
    35881 acatatcaag aaggtactcc cttagcttca gcagctttgt cggatgtttc tttgacgatt
    35941 gaagatggct cttatacagc tttaattggg cacacaggta gtggtaaatc aactatttta
    36001 caactcttaa atggtttatt ggtgccaagt caagggagtg tgagggtttt tgatacctta
    36061 atcacctcga cttctaaaaa taaagatatt cgtcaaatta gaaaacaggt tggcttggta
    36121 tttcagtttg ctgaaaatca gatttttgaa gaaacggttt tgaaggacgt tgcttttgga
    36181 ccgcaaaatt ttggagtttc tgaagaagat gctgtgaaga ctgcgcgtga gaaactggct
    36241 ctggttggaa ttgatgaatc actttttgat cgtagtccgt ttgagctgtc agggggacaa
    36301 atgagacgtg ttgccattgc aggcatactt gccatggagc cagctatatt agtcttagat
    36361 gagccaacag ctggtctaga tcctctaggg agaaaagagt tgatgaccct gttcaaaaaa
    36421 ctccaccagt cagggatgac catcgtcttg gtaacgcatt tgatggatga tgttgctgaa
    36481 tatgcgaatc aagtctatgt aatggaaaag ggacgtttag taaagggggg caaaccaagt
    36541 gatgtctttc aagacgttgt ttttatggaa gaagttcagt tgggagtacc taaaattacg
    36601 gccttttgta aacgattggc tgatagaggc gtgtcattta aacgattacc gattaagata
    36661 gaggagttca aggagtcgct aaatggatag tatgattttg gggcgttata tcccagggga
    36721 ttcgattgtt caccgattgg atccacgtag caaattgctt gctatgatgc tactgatttt
    36781 gattgtgttt tgggctaata accccttgac gaatctgatt ctttttatag cgacagggat
    36841 atttattgcc ttgtcaggag tatctctttc attttttatt cagggcttga agtctatgtt
    36901 tttcttgatt gccttcacaa ctatttttca actatttttc atttctaatg ggaatgtttt
    36961 atttgagttt tcgtttgtga gaatcacgga ttatgctttg caacaagctg ggattatttt
    37021 ttgtcgcttt gtattgatta ttttcttttc aactttgtta accttaacaa ccatgccttt
    37081 aagtttggca tcagctgtcg aagctttatt agcaccttta aagcgtgtga aagttccagt
    37141 tcatgaaatt ggattgatgc tgtctatgag tttgcgtttt gtcccaacct tgatggatga
    37201 tacgacgcgg attatgaatg cacagaaagc tcgtggagtg gattttggag aaggaagcat
    37261 cgttcaaaaa gtaaaggcga tgattcccat tttgattcct ctttttgcga caagtttaaa
    37321 acgtgcagat tccttggcta tcgctatgga agcgcgtggc tatcagggtg gaaaaggcag
    37381 aagtcaatac cgacaattga aatggactct aaaggatacg ttgaccattc ttgttattct
    37441 cgtacttggt tgttgtttat ttttcttaaa atcttagtag ctttcaggaa ttgataaaaa
    37501 gttactgtaa cagtttttga tataaaggta ggaatatgaa ccgttttaaa aaatcaaaat
    37561 atgtcattat tgtttttgtc actgttctgc ttgtgtcagc tctcttagcg acgacttatt
    37621 caagtacaat tgtgacaaaa ttaggagatg gaatctcatt ggttgataga gttgtacaaa
    37681 aaccttttca gtggtttgat tctgtcaaat cagatttggc tcatttgaca cgaacatata
    37741 atgaaaatga aagtttgaag aaacagcttt accaattaga agttaaatca aatgaggtgg
    37801 aaagtttaaa gacagaaaat gaacaactgc gccaattgct tgatatgaag tctaaattgc
    37861 aagccacaaa gactttagca gcagatgtta ttatgcgttc tccggtatct tggaagcagg
    37921 agttgacctt agatgcaggt agatcaaaag gtgcttctga gaacatgtta gctattgcaa
    37981 atggtggctt gattgggagt gtttcaaaag tagaggagaa ctctactata gtcaaccttc
    38041 tgacaaatac ggaaaatgct gataagattt ctgttaaaat tcaacatggc tctactacaa
    38101 tttatggaat tattattggc tatgacaagg aaaatgacgt tcttaaaatt agccaattaa
    38161 atagtaatag cgatattagt gcgggagata aggtgactac tggtggatta ggaaacttta
    38221 acgttgctga tattcctgtt ggtgaagtgg ttgccacaac gcatagtaca gactatttga
    38281 cacgagaagt aactgttaaa ttgagtgcag atactcataa tgtagatgtg atagaattag
    38341 tggggaattc ataatgagac agttgaagcg agttggagta tttttattgc ttcctttctt
    38401 tgttctaatt gacgcccata ttagccagct tctgggctca tttttccccc atgtacattt
    38461 ggctagtcat tttctttttc tatttctctt atttgagacg atagaagtat cagagtatct
    38521 ctacctagtc tattgttttg ttataggctt ggtttatgat gtttactttt tccatctaat
    38581 agggattaca actctcttat ttatcttatt gggagccttc cttcataaat tgaatagtgt
    38641 tattttgttg aatcgttgga caagaatgct agctatgatt gtgctgacat tcctgtttga
    38701 aatgggtagt tatcttttgg cttttatggt agggttgaca gtagatagca tgtcgatttt
    38761 tatagtctat agcttggtac cgacgatgat tttaaatttt ttatggatta ctgtttttca
    38821 atttattttt gaaaaatatt atctataaga acgacatata aatgtaacaa aggcgtaata
    38881 tttattaggc ctttttttgg tatactagta ttgtctttaa aagaaggagt atctacgtaa
    38941 tatgaagaaa aaaatcttag cgtcactttt attaagtaca gtaatggttt ctcaagtagc
    39001 tgttttaaca actgcgcatg cagaaacgac tgatgacaaa attgctgctc aagataataa
    39061 aattagtaac ttaacagcac aacaacaaga agcccaaaaa caagttgacc aaattcagga
    39121 gcaagtatca gctattcaag ctgagcagtc taacttgcaa gctgaaaatg atagattaca
    39181 agcagaatct aagaaactcg agggtgagat tacagaactt tctaaaaaca ttgtttctcg
    39241 taaccaatcg ttggaaaaac aagctcgtag tgctcaaaca aatggagccg taactagcta
    39301 tatcaatacc attgtaaact caaaatcaat tacagaagct atttcacgtg ttgctgcaat
    39361 gagtgaaatc gtatctgcaa acaacaaaat gttagaacaa caaaaggcag ataaaaaagc
    39421 tatttctgaa aaacaagtag caaataatga tgctatcaat actgtaattg ctaatcaaca
    39481 aaaattggct gatgatgctc aagcattgac tacgaaacag gcagaactaa aagctgctga
    39541 attaagtctt gctgctgaga aagcgacagc tgaaggggaa aaagcaagtc tattagagca
    39601 aaaagcagca gctgaggcag aggctcgtgc agctgcggta gcagaagcag cttataaaga
    39661 aaaacgagct agccaacaac aatcagtact tgcttcagca aacactaact taacagctca
    39721 agtgcaagca gtatctgaat ctgcagcagc acctgtccgt gcaaaagttc gtccaacata
    39781 cagtacaaac gcttcaagtt atccaattgg agaatgtaca tggggagtaa aaacattggc
    39841 accttgggct ggagactact ggggtaatgg agcacagtgg gctacaagtg cagcagcagc
    39901 aggtttccgt acaggttcaa cacctcaagt tggagcaatt gcatgttgga atgatggtgg
    39961 atatggtcac gtagcggttg ttacagctgt tgaatcaaca acacgtatcc aagtatcaga
    40021 atcaaattat gcaggtaatc gtacaattgg aaatcaccgt ggatggttca atccaacaac
    40081 aacttctgaa ggttttgtta catatattta tgcagattaa tttacagagg gactcgaata
    40141 gagccctctt ttcaggtttt accgtgacaa tccctattaa aaattatatc aaaatagctt
    40201 gaaaatattg gaaaagtatg gtaaaatgaa aattgtcgtg tgaacgataa tactcattct
    40261 tgatgaattg tgaagcagtt gcccttgggt cgttttgcga gttgaagtca agaagaggaa
    40321 aaaaacaaaa aggagaaata ctcatggcag taatttcaat gaaacaactt cttgaggctg
    40381 gtgtacactt tggtcaccaa actcgtcgct ggaatcctaa gatggctaag tacatcttta
    40441 ctgaacgtaa cggaatccac gttatcgact tgcaacaaac tgtaaaatac gctgaccaag
    40501 catacgactt catgcgtgat gcagcagcta acgatgcagt tgtattgttc gttggtacta
    40561 agaaacaagc agctgatgca gttgctgaag aagcagtacg ttcaggtcaa tacttcatca
    40621 accaccgttg gttgggtgga actcttacaa actggggaac aatccaaaaa cgtatcgctc
    40681 gtttgaaaga aattaaacgt atggaagaag atggaacttt cgaagttctt cctaagaaag
    40741 aagttgcact tcttaacaaa caacgtgcgc gtcttgaaaa attcttgggt ggtatcgaag
    40801 atatgcctcg tatcccagat gtgatgtacg tagttgaccc acataaagag caaatcgctg
    40861 ttaaagaagc taaaaaattg ggaatcccag ttgtagcgat ggttgacacc aatactgatc
    40921 cagatgatat cgatgtaatc atcccagcta acgatgacgc tatccgtgct gttaaattga
    40981 tcacagctaa attggctgac gctattatcg aaggacgtca aggtgaggat gcagtagcag
    41041 ttgaagcaga atttgcagct tcagaaactc aagcagattc aattgaagaa atcgttgaag
    41101 ttgtagaagg tgacaacgct taatttatac aaatagtaat tacctaggag ggcggggctt
    41161 agcccggctc tcctattttc aaaaaatata ggagaattaa aatggcagaa attacagcta
    41221 aacttgtaaa agagttgcgt gaaaaatctg gtgccggtgt tatggacgct aaaaaagcgc
    41281 ttgtagaaac agacggtgac atcgaaaaag cgattgaatt gcttcgtgaa aaaggtatgg
    41341 ctaaggcagc taagaaagct gaccgtgttg ctgcagaagg tttgactggt gtttatgtta
    41401 acggtaatgt tgcagcagtt attgaagtaa acgctgaaac tgacttcgtt gcaaaaaacg
    41461 ctcaattcgt tgaattggta aatactacag ctaaagtcat tgctgaagga aaacctgcta
    41521 ataatgaaga agctcttgct ttgataatgc cttcaggtga aactcttgaa gctgcatacg
    41581 tatctgcaac agcaactatc ggagagaaaa tctcattccg tcgctttgca ttgattgaaa
    41641 aaacagacgc acaacacttt ggagcatacc aacataacgg tggacgtatc ggtgttattt
    41701 cagttgttga aggtggagac gaagcacttg ctaaacaatt gtcaatgcac atcgcagcga
    41761 tgaaaccaac agttctttct tacaaagaat tggatgagca attcgttaaa gatgagttgg
    41821 cacaattgaa tcacgttatc gaccaagaca acgaaagccg tgcaatggtt aataaaccag
    41881 ctcttccaca cttgaagtat ggatcaaaag ctcaattaac tgatgatgtt attgctcaag
    41941 ctgaagctga catcaaagct gaattggctg cagaaggcaa accagaaaaa atctgggaca
    42001 aaattatccc aggtaaaatg gatcgcttca tgcttgataa tactaaagtt gaccaagctt
    42061 acacacttct tgcacaagtt tacatcatgg atgacagcaa gacagttgaa gcataccttg
    42121 aatcagttaa cgcttcggta gttgagtttg ctcgctttga agttggtgaa ggtatcgaga
    42181 aagctgcaaa cgacttcgaa gctgaagttg cagctacaat ggcagcagcc ttgaataact
    42241 aataatagaa aggaagcaat ttgcttcctt ttttgtatag ggcttatatt tttcctgaaa
    42301 ttgtttttcc cccagtctca ctcgattaga ataattaaaa caaaaagccc tataataagg
    42361 gctaagtgca tttaggagac tatacttcaa attcatagta agcgcgtcat aacaaggtat
    42421 ctatcctaat tccccaactt ccagtatact agataaaaaa taattatcgg aggaaaggta
    42481 ttgtactatg atgattcaac taagtgattt aggtcaagtt cacattgttt gtggcaagac
    42541 agatatgagg cagggaatag actcattagc ctatgtagtt aaaacccact ttgaattgga
    42601 ttctttctcc ggtcaagtct ttctcttttg tggtggacgt aaagaccgct ttaaagtcct
    42661 ttactgggat ggtcaaggat tttggctact atataaacgc tttgagaacg gaaaactgac
    42721 ttggctaagt acagaaaagg atgtcaaagc tctcacatct gaacaagtag actggcttat
    42781 gaagggcttt tctatcactc cccaaatata gtggatttaa actagaatag tacacctctg
    42841 cttctaaaac attgttagaa atcgatttga ctatcctgtt cttatttcat tttactataa
    42901 attcatcaga aagtcgtgat ttctattgaa atgaggactt tctttttata ctcatctgtt
    42961 ttcaaaaagc attctagtcc gtctccgatt aacgatggac tttatcacct ccttctccag
    43021 tccttgtatg acatcttcca aagttcgaaa ggctttattc ttaaatccac gtttacgaat
    43081 ctctttccac acttgttcaa tggggttcat ctctggtgtg tatggaggaa taaatgcaaa
    43141 gccaatatta gtcggaatct ttaaggtact tgatttatgc catatagcat tgtccataac
    43201 gagtaaaaga taatcatctg gataagcttg tgaaagctcc tattcctaaa gcccctttag
    43261 cgcataactt tggctcagct tctattatcg ctcacaccat ccatcagaag tttaatctga
    43321 aggtacccaa ttatcgccaa gaagaagatt gggctaggat gggtttacca atcacacgta
    43381 aggaaatctc taattggcat atcaagacga gtcaatacta tttggagccc ctttataacc
    43441 tcttgcgaga gagactattg actcagccct tacttcatgc ggatgaaact tcttataggg
    43501 tgctagagag tgatagtcag ctgacttact attggacttt tttgtctggg aaagctgaga
    43561 aacaagggat tacgctttac catcatgttc taatcgattt gttcatatct tatttcaatc
    43621 cattataaat agtgagaaat atctatccta tcttctagaa tgtcttccaa acgtggaaac
    43681 tctcgtaaac aaagaggttt tagaggccta tttaccatgg actaaagttg tacaagaaaa
    43741 gtgcaaataa gaaatctcca gattaggaac tatccgtgag ttctctagtc tggagatttt
    43801 tcaatagact tcgttattgg acggttacaa ttcataaagt gctgtagaga gataacgttc
    43861 accgttatct ggtgctaggg caaggacttt tttacctgta cctaattttt tggcaacctc
    43921 gatggctccg tagatagctg cagctgagga aatccctaca aggaagcctt cttttccacc
    43981 aatttcacgt ccgagtgcaa gagcgtcatc tgatgttaca cgaacgatac catcataggc
    44041 tttagtatca agtgtatcag gaataaatcc agctgagata ccttgaattt tgtgaggacc
    44101 aggtttttca ccagatagaa tagcagattc atctgcttct actgcaaaaa cttgaatgtt
    44161 agaattttct gatttgagtg catgagaaac accagaaatc gttccaccag tacctactcc
    44221 agcaacaaag gcatctaatc catctttacc gaaagcagct agtatctcag ctcctgttgt
    44281 tctttcgtgt acttctggat tagctggatt gtcaaattga agaggaagga aaccatcacg
    44341 ttcagcagcg atttcttgag ccttagcaat agcacctttc attccctcgc taccaggagt
    44401 taggacgagt tcagcaccat aagcttggat aattttacgt cgttctacac tcatagtttc
    44461 aggcataacg atgacgactt tatacccttt agcagcacct acccatgaaa gtccaatacc
    44521 ggtgtttcca cttgttgctt caacaatagt agaaccaggt ttcagaatac catcttgttc
    44581 agctttttca atcatgctaa gggcaatacg gtcttttaca gatgaaccag gattaaatgc
    44641 ttcaagcttt atatagacgt ctgcagcacc ttctggcacg atgttgttaa gtttaacaat
    44701 cggtgtttga ccgattaatt cagtaatgtt gttataaata gacatatgaa tacctctttg
    44761 tataagatat ctttagtata acgctatcca taccatttct atatatcata gatcaaagtc
    44821 attaattttc aagtgattgc gttcagctaa ttctagtaaa taggtgtgaa ggaaaacgat
    44881 atcaggtttc gtttgaattg cttcattttc tagtatattt tggtacgcct ctttttattt
    44941 tgctcgctaa agtagttgtg agaatgtcaa cgaaacgctg tattattcat tgtttacact
    45001 aagtttacag gaacttcaac ctctcgtaaa ccttggtcag ttaaagtgac ttttccatta
    45061 aaaaactcca caagtgcagc tttaatagtt tctttttctt ctttatcaac ataaatcatc
    45121 gtatcgactt gatctgtaaa gtttgtatcc agctccatga gaccatgttc tttaaggaag
    45181 ttactgtact cttggtactg agcataagac atttgaatag caatgccagc ctgttctttt
    45241 atttcaataa taccaatttc tttgacagct aaggcgacac tgccggcgta agcacgaatt
    45301 agtcctccag cgcctagttt aataccacca aagtagcgtg tcacgaccac acagacattg
    45361 gtgagattgt gattttctag taccccaagc atgggaacac cagcagtacc actaggctca
    45421 ccatcatcac ttgtacgttt aatttcacta cgttctccaa taatgaaggc agagcagtta
    45481 tgtgtcgctt tgtagtgttc ttttttgatg gcagtaatga agtcacgagc ctcttcttcg
    45541 ctataaacac gcttggcatg gcagataaag cgagattttt tgatttcttc ttggacttga
    45601 ccgtcctctt taattgtcct aaattccatg atttaattgt actaaaaaat catctaaagt
    45661 gctagttttt acgaataaag aagtatgaaa gtaaatttag attatctcgg tcgtttattt
    45721 actgagaatg aattaacaga agaagaacgt cagttggcgg agaaacttcc agcaatgaga
    45781 aaggagaagg ggaaactttt ctgtcaacgc tgtaatagta ctattctaga agaatggtat
    45841 ttgcccatcg gtgcttacta ttgtcgagag tgcttgctga tgaagcgagt cagaagtgat
    45901 caaactttat actattttcc gcaggaggat tttccaaagc aagatgttct caaatggcgc
    45961 ggccaattaa ctccttttca agagaaggtg tcagagggat tgcttcaagt agtagacaag
    46021 caaaagccaa ccttagttca tgcggtaaca ggagctggaa agacagaaat gatttatcaa
    46081 gtagtggcta aagtgatcaa tgcgggtggt gcagtgtgtt tggctagtcc tcgcatagat
    46141 gtttgtttgg agctgtacaa gcgcctgcaa caggattttt cttgcgggat agctttgcta
    46201 catggagaat cggaacctta ttttcgaaca ccactagttg ttgcaacaac ccatcagtta
    46261 ttgaagtttt atcaagcttt tgatttgctg atagtggatg aagtagatgc ttttccttat
    46321 gttgataatc ccatgcttta ccacgctgtc aagaatagtg taaaggagaa tggattgaga
    46381 atctttttaa cagcgacttc gaccaatgag ttagataaaa aggtccgttt aggagaacta
    46441 aaaagactga atttaccgag acggtttcat ggaaatccgt tgattattcc aaaaccaatt
    46501 tggttatcgg attttaatcg ctacttagac aagaatcgtt tgtcaccaaa gttaaagtcc
    46561 tatattgaga agcagagaaa gacagcttat ccgttactca tttttgcttc agaaattaag
    46621 aaaggggagc agttagcaga aatcttacag gagcaatttc caaatgagaa aattggcttt
    46681 gtatcttctg taacagagga tcgattagag caagtacaag cttttcgaga tggagaactg
    46741 acaatactta tcagtacgac aatcttggag cgcggagtta ccttcccttg tgtggatgtt
    46801 ttcgtagtag aggccaatca tcgtttgttt accaagtcta gtttgattca gattggtgga
    46861 cgagttggac gaagcatgga tagaccgaca ggagatttgc ttttcttcca tgatgggtta
    46921 aatgcttcaa tcaagaaggc gattaaggaa attcagatga tgaataagga ggctggtcta
    46981 tgaagtgctt gttatgtggg cagactatga agactgtttt aacttttagt agtctcttac
    47041 ttctgaggaa tgatgactct tgtctttgtt cagactgtga ttctactttt gaaagaattg
    47101 gggaagagaa ctgtccaaat tgtatgaaaa cagagttgtc aacaaagtgt caagattgtc
    47161 aattttggtg taaagaggga gttgaagtca gtcatagagc gatttttact tacaatcaag
    47221 ctatgaagga ttttttcagt cggtataagt ttgatggaga cttcctgtta agaaaagttt
    47281 tcgcttcatt tttaagtgag gagttgaaaa agtacaaaga gtatcaattt gttgtaattc
    47341 ccctaagtcc tgatagatat gctaacagag gatttaatca ggttgagggc ttggtagagg
    47401 cagcaggctt tgagtatcta gatttattag agaaaagaga agagagagcc agttcttcta
    47461 aaaatcgttc agagcgcttg gggacagaac ttcctttctt tattaaaagt ggagtcacta
    47521 ttcctaaaaa aatcctactt atagatgata tctatactac aggagcaact ataaatcgtg
    47581 ttaagaaact gttggaagaa gccggtgcta aggatgtaaa aacattttcc cttgtaagat
    47641 gaggaaaaaa tttgcaaaaa tagaatgaaa gcgttataat aaaatcataa aaacaaaaat
    47701 gtttagaaag aaggtactca tatgattaaa tatagtatcc gtggtgaaaa cctagaagta
    47761 acagaagcaa ttcgtgatta tgtagtttct aaactcgaaa agatcgaaaa gtacttccaa
    47821 ccagaacaag agttggatgc ccgaattaac ttaaaagttt atcgtgaaaa aacggctaaa
    47881 gtggaagtaa cgattccgct tggatctatt actctccgcg cagaagatgt atctcaagat
    47941 atgtatggtt caattgacct tgtaactgat aaaattgaac gtcagattcg taaaaataaa
    48001 acaaaaatcg agcgtaaaaa taaaaataag gtagcaactg gtcaattatt tacagatgct
    48061 ttggtggaag attcaaatat tgtccagtct aaagttgttc gttcaaaaca aattgattta
    48121 aaaccaatgg atttggaaga agcaattcta caaatggatt tattggggca tgatttcttt
    48181 atctatgtgg atgttgaaga tcagacaacc aatgtgattt atcgtcgtga ggatggcgaa
    48241 attggtttgt tagaggttaa agaatcttaa tttcaatatg tgtaaaggta ggtttactga
    48301 attgtaaact acctttttct tataattgat agaattactg attacacttt taaaaagtcg
    48361 ctttttgagg ggtattatgg tataatgggt gccaagaggt tttgaatgaa aaaattttat
    48421 gtaagtccaa tttttcctat tctagtagga ttgattgcgt ttggagtctt atccactttc
    48481 attatttttg ttaataataa tctgttgacg gttttaattt tgtttctttt tgtaggaggc
    48541 tatgtttttt tatttaagaa actgagagtg cattatacaa ggagtgatgt agaacagata
    48601 cagtatgtaa accaccaagc ggaagaaagt ttgacagctc tattggaaca gatgcctgta
    48661 ggtgttatga aattgaattt atcttctgga gaggttgagt ggtttaatcc ctatgctgaa
    48721 ttgattttga ccaaggaaga tggtgatttt gatttagaag ctgttcaaac gattatcaag
    48781 gcttcagtag gaaatccgtc tacttatgcc aagcttggtg agaagcgtta tgctgttcat
    48841 atggatgctt cttccggtgt tttgtatttt gtagatgtat ccagggaaca agccataaca
    48901 gatgaattgg taacaagtag accagtgatt gggattgtct ctgtggataa ttatgatgat
    48961 ttggaggatg aaacttctga gtcagatatt agtcaaatca atagttttgt agctaatttt
    49021 atatcagagt tttcagaaaa acacatgatg ttttctcgtc gggtaagtat ggatcgattt
    49081 tatctattta ctgactacac ggtgcttgag ggcttgatga atgataaatt ttctgttatt
    49141 gatgctttca gagaagagtc gaaacagaga cagttgccct tgaccttaag tatgggattt
    49201 tcttatggcg atggaaatca tgatgagata gggaaagttg ctttgctcaa tttgaacttg
    49261 gctgaagtac gtggtggcga ccaggtggtt gttaaggaaa acgacgaaac gaaaaatcca
    49321 gtttattttg gtggtgggtc tgctgcttca atcaagcgta cacggactcg tacgcgcgct
    49381 atgatgacag ctatttcaga taagattcgg agtgtagatc aggtttttgt agtcggtcac
    49441 aaaaatttag acatggatgc tttgggctct gctgtaggta tgcagttgtt cgccagcaat
    49501 gtgattgaaa atagctatgc tctttatgat gaagaacaaa tgtctccaga tattgaacga
    49561 gctgtttcat tcatagaaaa agaaggagtt acgaagttgt tgtctgttaa ggatgcaatg
    49621 gggatggtga ccaatcgttc tttgttgatt cttgtagacc attcaaagac agccttaaca
    49681 ttatcaaaag aattttatga tttatttacc caaaccattg ttattgacca ccatagaagg
    49741 gatcaggatt ttccagataa tgcggttatt acttatatcg aaagtggtgc aagtagtgcc
    49801 agtgagttgg taacggaatt gattcagttc cagaattcta agaaaaatcg tttgagtcgt
    49861 atgcaagcaa gtgttttgat ggctggtatg atgttggata ctaaaaattt cacctcgcga
    49921 gtaactagtc ggacatttga tgttgctagc tatctcagaa cgcgcggaag tgatagtatt
    49981 gctatccagg aaatcgctgc gacagatttt gaagaatatc gtgaggtcaa tgaacttatt
    50041 ttacaggggc gtaaattagg ttcagatgta ctaatagcag aggctaagga cacgaaatgc
    50101 tatgatacag ttgttattag taaggcagca gatgccatgt tagccatgtc aggtattgaa
    50161 gcgagttttg ttcttgcgaa gaatacacaa ggatttatct ctatctcagc tcgaagtcgt
    50221 agtaaactga atgtacaacg gattatggaa gagttaggcg gtggaggcca ctttaatttg
    50281 gcagcagctc aaattaaaga tgtaaccttg tcagaagcag gtgaaaaact gacagaaatt
    50341 gtattaaatg aaataaagga aaaggagaaa gaagaatgaa agtaatcttt ttagcagatg
    50401 ttaaaggaaa aggtaaaaaa ggcgaaatta aggaagtacc aacagggtat gcgcaaaact
    50461 ttcttatcaa aaagaatcta gccaaagaag cgactgctca agctgtaggt gaacttcgtg
    50521 gtaaacaaaa atcggaagaa aaagctcacg ctgagatgat tgcagaaggg aaagcaatta
    50581 aagcacaact tgaagcagaa gaaactgttg tagaatttgt tgaaaaagtt ggtccagatg
    50641 gtcgtacctt tggttctatt accaataaga agattgcaga agaattacaa aagcaatttg
    50701 gaattaagat tgataaacgt catattcaag tacaagctcc gattcgagcg gttggtttga
    50761 ttgatgtgcc agtgaaaatc tatcaagata tcacaagtgt aatcaatctt cgtgtgaaag
    50821 aaggataagt ttacaccttc ttgacaagat tgtaaaagga agggaagtct gatggcagaa
    50881 gtagaagagt tacgagtaca acctcaagat atcttagctg agcaatccgt tttaggggct
    50941 atctttattg atgagagtaa acttgttttt gtgcgagaat acattgagtc tcgggacttt
    51001 tttaagtatg cccatcgttt gattttccaa gccatggtcg atttatccga tcgtggtgat
    51061 gccatagatg caacaacggt tcgtactatc cttgataatc aaggtgattt acagaatatt
    51121 ggtggcttgt cttacttggt tgagattgtc aattctgtgc caacttctgc taatgcggag
    51181 tattatgcta agattgttgc agaaaaagca atgctacgtc gtttaattgc caagttgaca
    51241 gagtctgtca accaagctta cgaagcgtca caaccagctg atgaaattat tgctcaggca
    51301 gaaaaagggc tgattgatgt cagtgaaaat gcaaatcgaa gcgggtttaa gaacattcga
    51361 gatgtgttga atctcaactt tggaaatctg gaagctcgct cgcaacaaac gaccgatatt
    51421 acaggtattg cgacaggtta tcgtgatttg gatcatatga caacaggact tcatgaggag
    51481 gagttgatta tcttagcagc tcgtccagca gttggtaaga cagcatttgc cttgaatatc
    51541 gctcagaata ttgggactaa gttggacaaa acggttgcta ttttttcact cgaaatgggt
    51601 gcggaaagct tggtagaccg tatgttagct gcagaaggct tggtggagtc acattctatc
    51661 cgtacagggc aattgacaga tgaggagtgg caaaaatata ctattgctca gggtaatcta
    51721 gctaacgcca gtatctatat cgatgatacg ccaggtattc ggattacaga gattcgttct
    51781 cgttctcgta aattggctca agaaactgga aatcttggtt tgattttgat agactatttg
    51841 caacttatca cgggaactgg tcgagaaaat cgtcaacaag aagtttctga aatttctcgt
    51901 cagttgaaaa tactagccaa ggaattgaag gttccagtaa tcgctctgag tcagctttct
    51961 cgtggtgtag aacaacgtca ggacaagaga ccggtcttgt ctgatattcg tgaatctggg
    52021 tctattgagc aggacgctga tatcgtagct tttctctatc gcgatgacta ctatgaacgt
    52081 ggtggtgaag aagaggaggg tatcccaaat aataaggtgg aagttattat cgagaaaaac
    52141 cgtagtggag ctcgtggaac agtggaattg attttccaaa aagaatacaa taaattttca
    52201 agtatctcaa agagggaggc ataagatgtc agatgcattt acagatgtag ccaagatgaa
    52261 aaaaatcaaa gaagaaatca aggcacatga gggacaagtc gtagaaatga ctttggagaa
    52321 tggtcgtaag cgccaaaaaa atagattggg taagctaatt gaagtttatc catccctatt
    52381 tattgtggag tttggggatg tggaaggaga taaacaagtt aatgtttacg ttgaatcctt
    52441 tacttactca gatattctta cagaaaagaa tttgattcat tatcttgact aaagtgagaa
    52501 attttctcac tttttctttt ttctccgaat aatttaggtg aaggcaatca tcgctttata
    52561 ttatttttta aggaggaaga atgaaaattt taccgtttat agcaagagga acaagttatt
    52621 acttgaagat gtcagttaaa aagcttgttc cttttttagt agtaggattg atgctagcag
    52681 ctggtgatag tgtctatgcc tattccggag gaaatggatc gattgcgcgt ggggatgatt
    52741 atcctgctta ttataaaaat gggagccagg agattgatca gtggcgcatg tattctcgtc
    52801 agtgtacttc ttttgtagcc tttcgtttga gtaatgtcaa tggttttgaa attccggcag
    52861 cttatggaaa tgcgaatgaa tggggacatc gtgctcgtcg ggaaggttat cgtgtagata
    52921 atacaccgac gattggttcc attacttggt ctactgcagg aacttatggt catgttgcct
    52981 gggtgtcaaa tgtaatggga gatcagattg agattgagga atataactat ggttatacag
    53041 aatcctataa taaacgaatt ataaaagcaa acacgatgac aggatttatt cattttaaag
    53101 atttggatgg tggcagtgtt gggaatagtc aatcctcaac ttcaacaggc gaaactcatt
    53161 attttaagac caagtctgct attaaaactg aacccctagt tagtgcaact gtgattgatt
    53221 actattatcc tggagagaag gttcattatg atcaaattct cgaaaaagac ggctacaagt
    53281 ggttgagtta tactgcctat aatggaagct atcgttatgt tcaattggag gctgtgaata
    53341 aaaatcctct aggtaattct gttctttctt caacaggtgg aactcattat tttaagacca
    53401 agtctgctat caaaactgaa cccctagtta gtgcaactgt gattgattac tattatcctg
    53461 gggagaaggt tcattatgat cagatacttg aaaaagacgg ctacaagtgg ttgagttata
    53521 cggcttataa cggaagtcgt cgctatatac agctagaggg agtgacttct tcacaaaatt
    53581 atcagaatca atcaggaaat atctctagct atggatccaa taatagttca actgtcggtt
    53641 ggaagaaaat aaatggtagt tggtatcatt tcaaatcaaa tggttctaaa tcaacaggat
    53701 ggctgaaaga tggttctagc tggtattatt tgaaattatc tggtgaaatg cagacaggat
    53761 ggttaaagga gaatggttcg tggtattatc tgggtagttc aggggcaatg aaaacaggct
    53821 ggtaccaggt ctctggtaag tggtattatt cttactcttc aggcgcctta gctgttaata
    53881 cgacggtgga tggctacaga gtaaacagtg atggagaacg agtatagaaa attggagtag
    53941 gagaaatttc ctgctctttt ctgtaagcag tttccttgac atttttctta ttttgcgcta
    54001 tcatatatac atataatata tgggagtctg tgtacagtct gagaggaagt gttaaacttc
    54061 gaccgcacct gatctgggta atgccagcgg agggaacgat acttagtcta attttgcacc
    54121 ttttccatgt atggtaaagg tttttctttt ttttaaaagg aaaacgagaa gaggaggttc
    54181 ttatgaaagc aagcattgcc ttgcaagttt tacccctagt acaggggatt gatcggatag
    54241 ctgttattga tcaggtcatt gcttatctgc aaactcaaga agtgccgatg gtagtgacac
    54301 catttgaaac ggtcttggaa ggggagtttg atgagcttat gcgcattcta aaagaagcgc
    54361 tggaagtggc agggcaggag gcagacaatg tctttgccaa tgtcaaaata aatgtaggag
    54421 agattttaag tattgatgag aaacttgaga agtatactga gacgacacat tagtctattg
    54481 ggctttctcg gagtcttgtc aatctggcag ttagcaggtt ttcttaaact gctccccaag
    54541 tttatcctgc cgacacctct tgaaattctc cagccctttg ttcgtgacag agaatttctc
    54601 tggcaccata gctgggcgac cttgagagtg gctttactgg ggctgatttt gggagttttg
    54661 attgcctgtc ttatggctgt actcatggat agtttgactt ggctcaatga cctgatttac
    54721 cctatgatgg tggtcattca gaccattccg accattgcca tagctcctat cctggtcttg
    54781 tggctaggtt atgggatttt gcccaagatt gtcttgatta tcttaacgac aacctttccc
    54841 atcatcgtca gcattttgga cggttttagg cattgcgaca aggatatgct gaccttgttt
    54901 agtctgatgc gggccaagcc ttggcaaatc ctgtggcatt ttaaaattcc agtcagcctg
    54961 ccctactttt atgctggtct gagggtcagt gtctcctacg cttttatcac aacagtggta
    55021 tctgagtggt tgggaggctt tgaggggctt ggtgtttata tgattcagtc caagaaattg
    55081 tttcagtatg ataccatgtt cgctattatt attctggtat cgattatcag ccttttgggt
    55141 atgaagttgg tcgatattag tgaaaaatat gttattaaat ggaaacgttc gtagaattag
    55201 aatgtttctg aaaaagaaaa gaggaaatca aaatgaagaa aacatggaaa gtgtttttaa
    55261 cgcttgtaac agctcttgta gctgttgtgc ttgtggcctg tggtcaagga actgcttcta
    55321 aagacaacaa agaggcagaa cttaagaagg ttgactttat cctagactgg acaccaaata
    55381 ccaaccacac agggctttat gttgccaagg aaaaaggtta tttcaaagaa gctggagtgg
    55441 atgttgattt gaaattgcca ccagaagaaa gttcttctga cttggttatc aacggaaagg
    55501 caccatttgc agtgtatttc caagactaca tggctaagaa attggaaaaa ggagcaggaa
    55561 tcactgccgt tgcagctatt gttgaacaca atacatcagg aatcatctct cgtaaatctg
    55621 ataatgtaag cagtccaaaa gacttggttg gtaagaaata tgggacatgg aatgacccaa
    55681 ctgaacttgc tatgttgaaa accttggtag aatctcaagg tggagacttt gagaaggttg
    55741 aaaaagtacc aaataacgac tcaaactcaa tcacaccgat tgccaatggc gtctttgata
    55801 ctgcttggat ttactacggt tgggatggta tccttgctaa atctcaaggt gtagatgcta
    55861 acttcatgta cttgaaagac tatgtcaagg agtttgacta ctattcacca gttatcatcg
    55921 caaataacga ctatctgaaa gataacaaag aagaagctag caaagtcatc caagccatca
    55981 aaaaaggcta ccaatatgcc atggaacatc cagaagaagc tgcagatatt ctcatcaaga
    56041 atgcacctga actcaaggaa aaacgtgact ttgtcatcga atctcaaaaa tacttgtcaa
    56101 aagaatacgc aagcgacaag gaaaaatggg gtcaatttga cgcagctcgc tggaatgctt
    56161 tctacaaatg ggataaagaa aatggtatcc ttaaagaaga cttgacagac aaaggcttca
    56221 ccaacgaatt tgtgaaataa tgacagaaat tagactagag cacgtcagtt atgcctatgg
    56281 tcaggagagg attttagagg atatcaacct acaggtgact tcaggcgaag tggtttccat
    56341 cctaggccca agtggtgttg gaaagaccac cctctttaat ctaatcgctg ggattttaga
    56401 agttcagtca gggagaattg tccttgatgg tgaagaaaat cccaaggggc gcgtgagtta
    56461 tatgttgcaa aaggatctgc tcttggagca caagacggtg cttggaaata tcattctgcc
    56521 cctcttgatt caaaaggtgg ataaggcaga agctatttcc cgagcggata aaattcttgc
    56581 gaccttccag ctgacagctg taagagacaa gtatcctcat gaacttagcg gtgggatgcg
    56641 ccagcgtgta gccttactcc ggacctacct ttttgggcac aagctctttc tcttagatga
    56701 ggcctttagc gccttggatg agatgacaaa gatggaactc cacgcttggt atcttgagat
    56761 tcacaaacag ttgcagctaa caaccctgat catcacgcat agtattgagg aggccctcaa
    56821 tctcagcgac cgcatctata tcttgaaaaa tcgccctggg cagattgttt cagaaattaa
    56881 actagattgg tctgaagatg aggacaagga agtccaaaag attgcctaca aacgtcaaat
    56941 cttggcagaa ttaggcttag ataagtagaa aaatagggag ttggtgaaga ttatccttta
    57001 ccagcgccct ttttctttta aaaatgagaa aatttcggta taatagtcaa acaaggtcaa
    57061 ggtttaaaga gagaggtggg tttgttatga gatttaaaaa tacatcggat catattgagg
    57121 cctacatcaa ggcgatttta gatcaatctg gtatcgtgga gttgcaacgg agtcagttgg
    57181 cagatacctt tcaggttgtt cctagtcaga ttaactacgt gatcaagaca cgctttacgg
    57241 aaagtagagg ctacttggtt gaaagtaagc gtggtggtgg aggctacatt cgtataggac
    57301 gaattgagtt ttctagtcat catgaaatgc tccgggagct gctttactcg attggtgagc
    57361 gagtcagtca agaaatttat gaggatattc tccagctttt ggttgagcag gaattgatga
    57421 ccaagcagga gatgaatttg ctagaatcag tagctttgga tcgcgtttta ggagaagaag
    57481 ctccagttgt tcgagcaaac atgctacgtc agatcataca agaggtagat agaaaaggga
    57541 agtaagatga actattcaaa agcattgaat gaatgtatcg aaagtgccta catggttgct
    57601 ggacattttg gagctcgtta tctagagtct tggcacttgt tgattgccat gtctaatcac
    57661 agttatagtg tagcaggggc aactttaaat gattatccgt atgagatgga ccgtttagaa
    57721 gaagtggctt tggaactgac tgaaacggac tatagccagg atgaaacctt tacggaattg
    57781 ccgttctccc gtcgtttgca ggttcttttt gacgaagcag agtatgtagc gtcagtggtc
    57841 tatgctaagg tgctagggac agagcacgtc ctctatgcga ttttgcatga tggcaatgcc
    57901 ttggcgactc gtatcttgga gagggctggt ttttcttatg aagacaagaa agatcaggtc
    57961 aagattgctg ctcttcgtcg aaatttagaa gaacgggcag gctggactcg tgaagatctc
    58021 aaggctttac gccaacgcca tcgtacagta gctgacaagc aaaattctat ggccaatatg
    58081 atgggcatgc cgcagactcc tagtggtggt ctcgaggact atacgcatga tttgacagag
    58141 caagcgcgtt ctggcaagtt agaaccagtc atcggtcggg acaaggaaat ctcacgtatg
    58201 attcaaatct tgagccggaa gactaagaac aaccctgtct tggttgggga tgctggtgtc
    58261 gggaaaacag ctctggcgct tggtcttgcc cagcgtattg ctagtggtga cgtgcctgcg
    58321 gaaatggcta agatgcgcgt gttagaactt gatttgatga atgtcgttgc agggacacgc
    58381 ttccgtggtg actttgaaga acgcatgaat aatatcatca aggatattga agaagatggc
    58441 caagtcatcc tctttatcga tgaactccac accatcatgg gttctggtag cgggattgat
    58501 tcgactctgg atgcggccaa tatcttgaaa ccagccttgg cgcgtggaac tttgagaacg
    58561 gttggtgcca ctactcagga agaatatcaa aaacatatcg aaaaagatgc ggcactttct
    58621 cgtcgtttcg ctaaagtgac gattgaagaa ccaagtgtgg cagatagtat gactatttta
    58681 caaggtttga aggcgactta tgagaaacat caccgtgtac aaatcacaga tgaagcggtt
    58741 gaaacagcgg ttaagatggc tcatcgttat ttaaccagtc gtcacttgcc agactctgct
    58801 atcgacctct tggacgaagc agcagcaaca gtgcaaaata aggcaaagca tgtaaaagca
    58861 gacgattcag atttgagtcc agctgacaag gccctgatgg atggcaagtg gaaacaggca
    58921 gcccagctaa tcgcaaaaga agaggaagta cctgtctaca aagacttggt gacagagtct
    58981 gatattttga ccaccttgag tcgcttgtca ggaatcccag ttcaaaagct gactcagact
    59041 gacgctaaga aatatctaaa tcttgaagca gaactccata aacgggttat cggtcaagat
    59101 caagctgttt caagtattag tcgtgcgatt cgccgtaatc agtcaggaat tcgcagtcac
    59161 aagcgtccga tcggttcctt tatgttccta ggacccacag gtgtcggtaa gaccgagttg
    59221 gccaaggctt tggcagaagt tctctttgat gacgaatcag cccttatccg ctttgatatg
    59281 agtgagtata tggagaaatt cgcagccagc cgtctaaatg gagctcctcc aggctatgtg
    59341 ggttacgaag aaggtgggga gttgacagag aaggttcgca ataaacccta ttccgttctc
    59401 ctctttgatg aggtagagaa ggctcaccca gatatcttta atgttctctt gcaggttctg
    59461 gatgacggtg tcttgacaga tagcaaggga cgcaaggtcg atttttcaaa taccattatc
    59521 attatgacat cgaacctagg tgcgactgcc cttcgtgatg ataagactgt tggttttggg
    59581 gctaaggata ttcgttttga ccaggaaaat atggaaaaac gcatgtttga agaactgaaa
    59641 aaagcttata gaccggaatt catcaaccgt attgatgaga aggtggtctt ccatagccta
    59701 tctagtgacc atatgcagga agtggtgaag attatggtca agcctttagt ggcaagtttg
    59761 gctgaaaaag gcattgactt gaaattacaa gcttcagctc tgaaattgtt agcaaatcaa
    59821 ggatatgacc cagagatggg agctcgccca cttcgcagaa ccctgcaaac agaagtggag
    59881 gacaagttgg cagaacttct tcttaaggga gatttagtgg caggcagcac acttaagatt
    59941 ggtgtcaaag caggccagtt aaaatttgat attgcataaa agaataaaag tatcagcatc
    60001 tgaccataag tcacagtgga gtgaaactca atgaaaatca aaga
//
LOCUS       DBERXF010000008        56879 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.08, whole genome shotgun sequence.
ACCESSION   DBERXF010000008 DBERXF010000000
VERSION     DBERXF010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 56879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56879
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.08"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..186
                     /locus_tag="ACL8JK_000558"
     CDS             <1..186
                     /locus_tag="ACL8JK_000558"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785491.1"
                     /translation="NTGLPLKKWTFSRAFCRALKSSPNHQIEIRNSLDKTIDFSYSLS
                     FFYLPLYHTFSVYGSSL"
     gene            complement(183..2072)
                     /locus_tag="ACL8JK_000559"
     CDS             complement(183..2072)
                     /locus_tag="ACL8JK_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HGS1785492.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWSRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKTLQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2210..3775
                     /locus_tag="ACL8JK_000560"
     CDS             2210..3775
                     /locus_tag="ACL8JK_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGS1785493.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGF
                     KTGEEDTAIAIGLRKDDTRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            3775..4539
                     /locus_tag="ACL8JK_000561"
     CDS             3775..4539
                     /locus_tag="ACL8JK_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1785494.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(4738..4953)
                     /locus_tag="ACL8JK_000562"
     CDS             complement(4738..4953)
                     /locus_tag="ACL8JK_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785495.1"
                     /translation="MAKTNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(5823..7073)
                     /gene="ilvA"
                     /locus_tag="ACL8JK_000563"
     CDS             complement(5823..7073)
                     /gene="ilvA"
                     /locus_tag="ACL8JK_000563"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HGS1785496.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7123..7479)
                     /locus_tag="ACL8JK_000564"
     CDS             complement(7123..7479)
                     /locus_tag="ACL8JK_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGS1785497.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(7717..7953)
                     /locus_tag="ACL8JK_000565"
     CDS             complement(7717..7953)
                     /locus_tag="ACL8JK_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785498.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKY"
     gene            complement(8060..9082)
                     /gene="ilvC"
                     /locus_tag="ACL8JK_000566"
     CDS             complement(8060..9082)
                     /gene="ilvC"
                     /locus_tag="ACL8JK_000566"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGS1785499.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9148..9624)
                     /gene="ilvN"
                     /locus_tag="ACL8JK_000567"
     CDS             complement(9148..9624)
                     /gene="ilvN"
                     /locus_tag="ACL8JK_000567"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HGS1785500.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9617..11317)
                     /locus_tag="ACL8JK_000568"
     CDS             complement(9617..11317)
                     /locus_tag="ACL8JK_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HGS1785501.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11517..13184)
                     /locus_tag="ACL8JK_000569"
     CDS             complement(11517..13184)
                     /locus_tag="ACL8JK_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGS1785502.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13187..13552)
                     /locus_tag="ACL8JK_000570"
     CDS             complement(13187..13552)
                     /locus_tag="ACL8JK_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS1785503.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13709..13897)
                     /gene="rpmB"
                     /locus_tag="ACL8JK_000571"
     CDS             complement(13709..13897)
                     /gene="rpmB"
                     /locus_tag="ACL8JK_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGS1785504.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSCKVERV"
     gene            complement(14016..14450)
                     /locus_tag="ACL8JK_000572"
                     /pseudo
     CDS             complement(14016..14450)
                     /locus_tag="ACL8JK_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163337.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            complement(14926..16470)
                     /locus_tag="ACL8JK_000573"
     CDS             complement(14926..16470)
                     /locus_tag="ACL8JK_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGS1785505.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16683..16985
                     /gene="gatC"
                     /locus_tag="ACL8JK_000574"
     CDS             16683..16985
                     /gene="gatC"
                     /locus_tag="ACL8JK_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGS1785506.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDHLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            16985..18451
                     /gene="gatA"
                     /locus_tag="ACL8JK_000575"
     CDS             16985..18451
                     /gene="gatA"
                     /locus_tag="ACL8JK_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGS1785507.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            18451..19893
                     /gene="gatB"
                     /locus_tag="ACL8JK_000576"
     CDS             18451..19893
                     /gene="gatB"
                     /locus_tag="ACL8JK_000576"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGS1785508.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            20017..21060
                     /locus_tag="ACL8JK_000577"
     CDS             20017..21060
                     /locus_tag="ACL8JK_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HGS1785509.1"
                     /translation="MATMKAARWHAAKDVRIQEIEVPEVLPHQVKVAVKFTGICGTDL
                     HEFLDGPIFIPTDEHVYSGQKAPVTLGHEFSGEIIEVGSDVTRVKVGDRVAVEPILAK
                     NNLVGDYNLDPNLNFVGLAADGGFAKYCVLDGDLVHVIPDSLSYEQAALTEPAAVAVY
                     AVRQSSLKAGDTAVVFGLGPIGLLIVEALRAAGASKIYAVELSPERQAKAEELGAIVV
                     RPEEGETAVEAIHRLTNGGVDVSYEVTGVPVVLGQALAAVHKAGECMVVSIWEREANI
                     NPNEFAIQEKTLKGIIAYRHIFPKVLELMEQGYFSAEKLVTKKIKLENIVEEGFIELT
                     QDKSQIKILVEPE"
     gene            complement(21085..21315)
                     /locus_tag="ACL8JK_000578"
     CDS             complement(21085..21315)
                     /locus_tag="ACL8JK_000578"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785510.1"
                     /translation="MVNVKEYPLYFFSYSMEIKEQTRKLAASCSKHCFEVVDRTDEVS
                     NHIYGNVTLTWSEEIFEEYYISKGRSKFTPTC"
     gene            21438..21998
                     /gene="efp"
                     /locus_tag="ACL8JK_000579"
     CDS             21438..21998
                     /gene="efp"
                     /locus_tag="ACL8JK_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGS1785511.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            22020..22409
                     /locus_tag="ACL8JK_000580"
     CDS             22020..22409
                     /locus_tag="ACL8JK_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS1785512.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            22402..22824
                     /gene="nusB"
                     /locus_tag="ACL8JK_000581"
     CDS             22402..22824
                     /gene="nusB"
                     /locus_tag="ACL8JK_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGS1785513.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFVYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(22873..23067)
                     /locus_tag="ACL8JK_000582"
     CDS             complement(22873..23067)
                     /locus_tag="ACL8JK_000582"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HGS1785514.1"
                     /translation="MILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFFNFL
                     NHAKPIWIFVYNYIYYHFFR"
     gene            complement(23122..23597)
                     /locus_tag="ACL8JK_000583"
                     /pseudo
     CDS             complement(23122..23597)
                     /locus_tag="ACL8JK_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(23615..23800)
                     /gene="briC"
                     /locus_tag="ACL8JK_000584"
     CDS             complement(23615..23800)
                     /gene="briC"
                     /locus_tag="ACL8JK_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HGS1785515.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(24063..24830)
                     /locus_tag="ACL8JK_000585"
     CDS             complement(24063..24830)
                     /locus_tag="ACL8JK_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGS1785516.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(24827..25693)
                     /gene="accD"
                     /locus_tag="ACL8JK_000586"
     CDS             complement(24827..25693)
                     /gene="accD"
                     /locus_tag="ACL8JK_000586"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGS1785517.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(25730..27097)
                     /gene="accC"
                     /locus_tag="ACL8JK_000587"
     CDS             complement(25730..27097)
                     /gene="accC"
                     /locus_tag="ACL8JK_000587"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGS1785518.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(27109..27531)
                     /gene="fabZ"
                     /locus_tag="ACL8JK_000588"
     CDS             complement(27109..27531)
                     /gene="fabZ"
                     /locus_tag="ACL8JK_000588"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGS1785519.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(27528..28013)
                     /gene="accB"
                     /locus_tag="ACL8JK_000589"
     CDS             complement(27528..28013)
                     /gene="accB"
                     /locus_tag="ACL8JK_000589"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGS1785520.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(28016..29251)
                     /gene="fabF"
                     /locus_tag="ACL8JK_000590"
     CDS             complement(28016..29251)
                     /gene="fabF"
                     /locus_tag="ACL8JK_000590"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGS1785521.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(29273..30004)
                     /gene="fabG"
                     /locus_tag="ACL8JK_000591"
     CDS             complement(29273..30004)
                     /gene="fabG"
                     /locus_tag="ACL8JK_000591"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGS1785522.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQVGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(30038..30958)
                     /gene="fabD"
                     /locus_tag="ACL8JK_000592"
     CDS             complement(30038..30958)
                     /gene="fabD"
                     /locus_tag="ACL8JK_000592"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGS1785523.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(30951..31925)
                     /gene="fabK"
                     /locus_tag="ACL8JK_000593"
     CDS             complement(30951..31925)
                     /gene="fabK"
                     /locus_tag="ACL8JK_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HGS1785524.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(32044..32268)
                     /locus_tag="ACL8JK_000594"
     CDS             complement(32044..32268)
                     /locus_tag="ACL8JK_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGS1785525.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(32328..33302)
                     /locus_tag="ACL8JK_000595"
     CDS             complement(32328..33302)
                     /locus_tag="ACL8JK_000595"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGS1785526.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(33302..33736)
                     /locus_tag="ACL8JK_000596"
     CDS             complement(33302..33736)
                     /locus_tag="ACL8JK_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGS1785527.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(33830..34615)
                     /locus_tag="ACL8JK_000597"
     CDS             complement(33830..34615)
                     /locus_tag="ACL8JK_000597"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HGS1785528.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRVSSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            34984..36348
                     /locus_tag="ACL8JK_000598"
     CDS             34984..36348
                     /locus_tag="ACL8JK_000598"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGS1785529.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREIGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            36351..36722
                     /locus_tag="ACL8JK_000599"
     CDS             36351..36722
                     /locus_tag="ACL8JK_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGS1785530.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            36936..38210
                     /gene="serS"
                     /locus_tag="ACL8JK_000600"
     CDS             36936..38210
                     /gene="serS"
                     /locus_tag="ACL8JK_000600"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGS1785531.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(38235..39134)
                     /locus_tag="ACL8JK_000601"
     CDS             complement(38235..39134)
                     /locus_tag="ACL8JK_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGS1785532.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFCVLGAYLIWLRKKV"
     gene            complement(39244..39792)
                     /locus_tag="ACL8JK_000602"
     CDS             complement(39244..39792)
                     /locus_tag="ACL8JK_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGS1785533.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(40010..41332)
                     /locus_tag="ACL8JK_000603"
     CDS             complement(40010..41332)
                     /locus_tag="ACL8JK_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGS1785534.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMVLPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(41423..41511)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(41675..44011)
                     /locus_tag="ACL8JK_000604"
     CDS             complement(41675..44011)
                     /locus_tag="ACL8JK_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGS1785535.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYTNLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(44115..44663)
                     /locus_tag="ACL8JK_000605"
     CDS             complement(44115..44663)
                     /locus_tag="ACL8JK_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGS1785536.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(44660..44962)
                     /gene="zapA"
                     /locus_tag="ACL8JK_000606"
     CDS             complement(44660..44962)
                     /gene="zapA"
                     /locus_tag="ACL8JK_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGS1785537.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            45049..45930
                     /gene="rnhC"
                     /locus_tag="ACL8JK_000607"
     CDS             45049..45930
                     /gene="rnhC"
                     /locus_tag="ACL8JK_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGS1785538.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQLVEENRGQNLPLIGTDEVGNGSYFGGLAVVASFV
                     TPDQHAFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANCFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            45934..46548
                     /gene="lepB"
                     /locus_tag="ACL8JK_000608"
     CDS             45934..46548
                     /gene="lepB"
                     /locus_tag="ACL8JK_000608"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGS1785539.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            46628..46750
                     /locus_tag="ACL8JK_000609"
     CDS             46628..46750
                     /locus_tag="ACL8JK_000609"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785540.1"
                     /translation="MKIKEQTRKLAVGCLKQCFEVVDRTDEVSSKYCFEVADGS"
     gene            46827..49193
                     /locus_tag="ACL8JK_000610"
     CDS             46827..49193
                     /locus_tag="ACL8JK_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGS1785541.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(49241..50524)
                     /gene="tig"
                     /locus_tag="ACL8JK_000611"
     CDS             complement(49241..50524)
                     /gene="tig"
                     /locus_tag="ACL8JK_000611"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGS1785542.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEEALYQDAMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQSLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(51323..52459)
                     /locus_tag="ACL8JK_000612"
     CDS             complement(51323..52459)
                     /locus_tag="ACL8JK_000612"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HGS1785543.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIADEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(52521..52958)
                     /locus_tag="ACL8JK_000613"
     CDS             complement(52521..52958)
                     /locus_tag="ACL8JK_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1785544.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPIGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(52960..54915)
                     /locus_tag="ACL8JK_000614"
     CDS             complement(52960..54915)
                     /locus_tag="ACL8JK_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS1785545.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRAIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(54939..56708)
                     /locus_tag="ACL8JK_000615"
     CDS             complement(54939..56708)
                     /locus_tag="ACL8JK_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HGS1785546.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLGSPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
BASE COUNT        16878 a        12804 c        10635 g        16562 t
ORIGIN      
        1 aacacaggat tacctttgaa aaaatggact ttttcaaggg ctttttgccg tgctctaaaa
       61 tcatcgccaa atcatcaaat tgaaataaga aatagtttag ataaaactat tgacttttct
      121 tatagtttgt ctttcttcta tcttccatta tatcatactt tttcagtcta tggtagctct
      181 ctttaaaagg ctccgatact gccgccacct ccgcctccag agaagccacc gccagaactt
      241 ccacttccag aagatacgga gtaggtactt gctgtatttg cgacactagc ataatggctc
      301 atttgcgcgc ttgaatgata aaacatactg tgccagccat aagctacata gagattgata
      361 tctggatttt caacttgaat ctgatgaacc ttcatcaaat gactaacctt gtccgcatag
      421 ccaaataagg ttgcatagac caagagacga ttccaaacaa caatactttc caattcagcc
      481 ttatccagtc gtgcaatctc acgtaacata ttttcaaaac tggtccagag atagtagacc
      541 tcagctcccg cttcatttag aacaccatca cgattatcta gtcgaagctt ccaataatag
      601 aaaacagaca aaactaaccc tagaaaacca agtattggca aagggaggta aagatagcca
      661 tgaacgtcta aactgtacaa gaacaaacca aatccgataa ataggggcaa gatagtcaag
      721 acacccatac ccacttgcaa agtcttttcc aaaccagtta aaggacgata gtaatctggg
      781 agcccccaga aggaaactcg ttttctcact ccttcttgca tctggttcaa tacctcttca
      841 aaagaagatt tgagttgaag ccctcttgct tgaatccgtt tttcatcaga aactttggct
      901 ctacgataaa gactatcaga taccttgtaa tccgcaaaca aattggaaag agtggcttct
      961 tttttgcctg aaaaggctag atttagacag tctctctcaa atcttgacaa accatcttct
     1021 ttcaccaatc tcaagccaac tgcatctcct tctgaaataa tagagacatt cccacggtct
     1081 atcacatcta gcaaggtagc ttgaataagt tgatcaaagg tgaattttcc agctcccttg
     1141 accaagggac tcacttcctc caaggaggtc gagtagactg cttctgataa aaccataggc
     1201 tctaattcca ttggtggttc atagagacga tgatttttgg catatttgac tgaaggagtg
     1261 gtctttcttc tataaataaa atagaagcag acactcaata acaaggagat agaaaggatc
     1321 gaagggagga cccaagtaac gagttgttta ctctgatctt tttctctaac aatcgagtct
     1381 tctatcttat taaactcttc taaacgattc cctttcaagc cctgatccct agcgctagca
     1441 aaatcggtcc gagaccaata ggcatgcaac tcaactccac gcttagccgg aagattgtct
     1501 aaacggatag tataatcaag gttactcttt tcaatcgttc cctctctaaa aagtttccct
     1561 gtatggaaaa agagtttttc agcccccttg tctcccctta catgaaattc aaacttttca
     1621 atagactctg aactatctgt cagaggttgc caatttaatt cagcgatatc atcataaagg
     1681 aaaagtaaat tttttaagtt ccagacgagg tcaacttcaa ctatgtcgcc ctcctgacct
     1741 ggattataga ctctcacagt ataaccatcc gcttcttctg ttacttcgct agtcacatct
     1801 gctagttctg caccgttttt cgcagcctga acctttggat gagggtcaat gtcaaacccg
     1861 ctaggcatct taccagcacg tccaagtccc acgatttggc ccttaaagtc ctcctcaaac
     1921 tggtaaacta tcttctgtct aaactctgcc gtattatctg catgaatata caaatcccct
     1981 tgataagagt ttatcttgaa atcaatggca aaaacagaga gtggaagaag gcaaaacaag
     2041 cctaacacca gtaagaaaaa agtttttttc atcaactaag cccccttttt atctttctta
     2101 tcattatagc attttttcgt aagtaaaggc ttacttatgt tgaaaaatta cgcatttttc
     2161 gataaaatag gagacagtta ttttttaata gatcagaata ggagaaatca tgagaaaaat
     2221 atacttatct attttcacaa gtctcttgct gatgctagga cttgtcaatg ttgctcaagc
     2281 cgatgaatat ttacgcatcg ggatggaagc agcatatgct ccctttaact ggacccagga
     2341 tgatgatagc aacggagctg tcaaaatcga tgggaccaat cagtatgcca acggatacga
     2401 tgttcaaatc gccaagaaaa tcgctaagga cttaggtaaa gaacctttgg ttgttaaaac
     2461 caagtgggaa ggtctagtcc ctgcccttac ttctggtaag attgacatga ttatcgcagg
     2521 tatgagtcca actgcagaac gcaaacaaga aattgccttt tcgagcagtt actacactag
     2581 cgaaccagtt ctactggtca aaaaagattc tgcctatgca agtgctaaat ctttggatga
     2641 ctttaatggt gcgaaaatca cttctcaaca aggggtctac ctttatgact tgattgcaca
     2701 aatcacaggt gctaaaaaag aaacagccat gggagacttc gctcaaatgc gccaagctct
     2761 tgaggctggt gtcatcgacg cctatgtttc tgaacgccca gaagctctga ctgccgaagc
     2821 cgctaactct aagttcaaga tggtccaagt agaaccaggt ttcaaaactg gggaagaaga
     2881 tacagctatc gccattggac ttcgtaaaga tgacactcgt attagccaaa tcaatgccag
     2941 cattgaaacc atttcaaagg acgaccaagt tgccctgatg gatcgtatga tcaaggaaca
     3001 acctgccgaa gctacaacaa ctgaagagac tagcagtagt ttctttagcc aagtcgctaa
     3061 aattctttct gaaaactggc aacaactctt gcgtggtgct ggtatcactc ttttaatctc
     3121 tatcgtcgga accatcatag gtctcattat tggacttgcc attggtgttt tccgtactgc
     3181 tcctctctct gaaaacaaag ccatttatgg ccttcaaaaa ctagtcggct gggttctcaa
     3241 tgtctacatt gaaattttcc gtggtacccc aatgatcgtt caatcgatgg ttatctacta
     3301 tggaactgcc caagctttcg ggatcaacct tgaccgtaca ctggctgcta tcttcatcgt
     3361 ttcaatcaat accggtgcct acatgactga aatcgtccgt ggtggtatcc tagcagttga
     3421 caagggacaa tttgaagctg cgactgctct tggtatgacc cataaccaga ccatgcgtaa
     3481 gattgtccta cctcaggtag tccgtaacat cctacctgca actggtaatg aatttgtcat
     3541 caatatcaaa gatacatctg tattgaacgt tatctctgtt gtcgaacttt atttctcagg
     3601 aaataccgtg gcaacacaaa cctatcaata cttccagaca tttacaatca tcgccgtgat
     3661 ttactttgtc ctcaccttca ccgtaacacg tatcctacga tttatcgagc gccgaatgga
     3721 catggatacc tatactacag gtgctaacca aatgcaaacg gaggatttga aataatgaca
     3781 caagcaatcc ttgaaattaa acacctcaaa aaatcctatg gacaaaacga agtgctaaaa
     3841 gacatttcac tcactgtcca caagggagag gtcatctcta tcatcggaag ctctggaagc
     3901 ggaaaatcga ccttcctacg ctccattaac ctacttgaaa caccaactga tggacaaatc
     3961 ctttatcatg gacaaaacgt cctcgaaaaa ggctatgacc tcacgcaata ccgtgaaaag
     4021 ttggggatgg ttttccaatc ctttaacctc tttgaaaatc tcaatgttct tgaaaacaca
     4081 atcgtcgctc agacaactgt cctaaaacgc gaacgcacag aagctgaaga aattgccaaa
     4141 gaaaacctgg aaaaggtcgg catgggagaa cgctactggc aagcgaaacc caaacaactc
     4201 tcaggtggtc aaaaacaacg tgtggccatt gctcgtgccc tttcaatgaa tcctgacgcc
     4261 attctctttg atgaaccaac atcagctctc gatccagaaa tggttggaga ggtcctcaaa
     4321 atcatgcaag atctggctca ggaaggcttg accatgattg tcgtaaccca tgaaatggaa
     4381 tttgcccgtg atgtctctca ccgtgttatc tttatggata agggtgtgat tgctgaagaa
     4441 ggtaaaccag aagacctctt cactaatcct aaagaagacc gtacaaaaga atttcttcaa
     4501 cgttatctca tactcaatga aaatcaaaga gcaaactagg cagctagccg caggttgctc
     4561 aaaacactgt tttgaggttg cagatagagc tgacgtggtt tgaagagatt ttcgaagagt
     4621 atcaaataaa aagaaaaggc tgcatcaacc gtgcagtctt tttgctgtcc tcaaaatgaa
     4681 aaggcagatt ctctatctct actacttgaa ggtcaagaat ccgccgttat ccaaagatta
     4741 atcttcaaat ttttcataat ttttttcata gaaatcaatt aggcctaggg ctgtttcaaa
     4801 tgaaatattt tttacttttg cacgaccctg cgccagagca atgatagaca tttcacgcgc
     4861 attcgtttct ttagagatac ggtagcctgt gattttctta tcacgaaccc agccaacaac
     4921 tgattctact ttttcaaagt ttgtcttagc catgtttttc tcctattttc ttctttataa
     4981 tatttaattg tatacgtttt tactactttt gtcaataaaa aaaacatata ttcaacgaaa
     5041 ataattagtt cagaattttc ttacttcctt tttaaatccg ataatatata ggttttgcta
     5101 gcctctacac cataaatatt tgctaataaa aatactgtat tattaccctc ttaaggtgcg
     5161 aaattattca agttcttaaa aatgcttctc tatttccgta agatagctta tttcttcgat
     5221 ttaagaactg aagatgatag ttctaacctt tagaaatcca agccttcact agctcaaaaa
     5281 ctcctatctt tcttcctcaa taaatcatct gagagatagg tattccttat atccttcaaa
     5341 ttcatcactc ctttggatat tgaggtgcta gcctagaagc agacacccga ttatctaaac
     5401 catccttaat aaagatgaca agacagataa actcagttaa ttacttatat atccttttaa
     5461 tatggtatat ttgtcaacaa aaagaaatca aatcatacct tatactcaat gaaaatcaaa
     5521 gagcaaacta ggaagctagc cgcaagttgc tcaaaacact gttttgaggt tgcagataga
     5581 gctaacgtgg tttgaagaga ttttcgaaga gtattaaaga cagtgtgact atgcttgtca
     5641 atagatagga aatcaaaatg aaggatggaa atctgagcca aacatcataa gtgctataat
     5701 gaacagaagt aagaattgca cgataagttt tctaaaacca taggaatcgt cccctttctt
     5761 catcttcatt atagcacata tacatcagtt gtacaaataa tatgatattt ttttattagt
     5821 cctcagacaa gcatattata aagcgtttca ttaccattta agttaatata agctggatca
     5881 aaaccttcca ttctacggat caaacctgca taatcatgct tatctgccaa agcgatccca
     5941 atcaatactg ggcctgttcc cttgctagct cgtttgatat actcaaaacg tgtgatatca
     6001 tcatttggcc ccaggatatc atttacaaac tcacgcaaag ctcctggacg ctgtggaaaa
     6061 ttgaccacaa agtaatgttt gataccatca taaatcaagg cacgctcttc catttctggc
     6121 atacggttga tatcattatt tcctccagaa atgatacaac aaatggtttt ccccttaata
     6181 tattcagcta aaacctctaa agaggcgata ctagccgctc cagcaggctc tgcgactatc
     6241 ccttgcttag agtaaaggtc aatcaaggtt tcagaaatca atccctcatc gacacctacc
     6301 aaagtttgaa tatgttgacg agttgcttca taggtcaact gacctacctt ttgcacagca
     6361 atcccatccg caaatttatc aatttccttg agtttgactg gacctccagc ctcaaaggca
     6421 gctttcatgg aacgcgctcc attcgcctct actccgataa cctcaatctc tggacttgtt
     6481 tccttgatat aggtagaaac cccggcaatg agaccgccac caccaacagg aaccaagaca
     6541 gcatcaaaat caatcgattc ttttcgagct tcttctaaaa tctcataagc aactgttcct
     6601 tgacctgctt gaacatgagc atcatcaaaa ggatcaataa aggtacgatt ttcagagact
     6661 gtaaattctt gagctgcttt ggctgaggca tcaaaggtat ctccaactag tttaatagtt
     6721 acaaaatccc caccaaaaaa gcgaacctga ccaatctttt gttgtggcgt agtaataggc
     6781 ataaagatag tagcaggaat tttcatttca ttacaagtat aggctactcc ctgcgcatga
     6841 tttcccgcag aagcgcagac taccccacgt tcacgttctt ccttgctgag ctgggaaatg
     6901 gcataatagg caccacgaat tttaaaggag cgaacacgct gggcattttc ttttttcaaa
     6961 taaatcttag caccatactt ctccgataaa taatgatcgt aatccagtgg agtattcaca
     7021 accacaccgt tcaagacctt gtgagccttg attatatctt ttgaacttaa catataaaac
     7081 ctctttttct ataaaaaaca gtcactaatg actgtttttt agttattcat ctccgaaaac
     7141 ttcagtaaca ctttcatggt atttatgagc catacgaatc gaaaactctt taggaagttc
     7201 ataacgattt gtggaaatcc aatcatataa ccattctacc aaactttctt cactatcatt
     7261 acgatggaag ataaaatagt ttaaaatttc tttatattct acatcattca aatccaacgt
     7321 gtctacaaat tgactacgag gaacaaaatt agaatctaat tttcttagtt gatctgtcaa
     7381 ttctcccaat tgtaaatcca actgaaaaaa tagtttttgc agttgcctat cagtttcatc
     7441 acatcctgtc ttgatagaaa acaaattggt aatattcata tgatttcaac ccctaaataa
     7501 gtacatctaa tatcccacga atagctgaag ctaaagtttt cgcagtccag tcatttaaac
     7561 ccgattcttt caatccagat gcaataattt gctctatttg atataaaccg ccatctatcg
     7621 tctcatttat tctgcgaaga ggaccttcaa tataggataa agcttctccg aatctaacag
     7681 ctgatttagg tcctaatgat ttaccaacta tatttgttaa tattttttat ttctcaaaat
     7741 ccatttcgct atataacgag cagatttagt cgcaccagct ctctcaaacg gagaatgaat
     7801 ttcaagacct tcttctctag ctatttgtgc caatttgaag aattgttcaa aggtcatatg
     7861 caacctacca tcttcaaaat tagcatcatc ataaatgtta attacagcat tttcatcata
     7921 cgaccaatct gctttatttt ggtctgctag cactattacc gacggtgtaa ttacattata
     7981 caactagaac caataataac gatgcaattt ttctcataat ctttttcata aaatcatctc
     8041 cagcgctata tatttctaat tagttataga ttttgaatgc atcatcgtcg tttttaccaa
     8101 cgaatggcat tgctttacgc aattctgcac caactttttc aatttcaagg ttagctgctt
     8161 gttcacggta agcagtcaat tttggacgtc cagctttata gtcatttaca aagtcatttg
     8221 caaatttacc attttggatg tctgccaaga cagccttcat attttcttta acttgttcag
     8281 tgattacacg tggacctgat acatagtcac cgtattcagc agtgtttgaa atagattgac
     8341 gcattttctt gaatccacct tcgtagatca agtcaacgat caatttcatt tcgtgaagaa
     8401 cttcaaagta agccaattct ggagcgtaac ctgcttctgt caagacttcg aaacctgctt
     8461 cgataagggc agtcaaacca ccacaaagta cagcttgttc accaaacaaa tcttcttcag
     8521 tttcttcttt gtaagttgtt tcaagaagac ctacacgagc cgctccaaca cctttacacc
     8581 agtccatagc aatgttttta gcatttcctg ttgcatcttg gtatactgca taaagagctg
     8641 gaacaccaaa tccttcttcg taagtacgac gtaccaagtg tcctggtcct ttaggagcac
     8701 acatgaagac atctacatcc gcaggaactt tgataaattc aaagtggatg ttgaaaccat
     8761 gggcaaatcc aactgcgttt ccagcttcca agtttggagc gatttctgct tcgtacaatt
     8821 cttgttgaat ttcgtctggc gccaagatca taataacatc agccaactta gtagcttctg
     8881 ctactgtgta agtatcaaat ccatcttctt ttgctttatc aaaagattta cctggacgta
     8941 caccgataat aacgtcacga cctgaatcac gcaagttttg agcatgcgca tgcccttgtg
     9001 aaccataacc gataacggcg atttttttac cgtcaagtgc tgctacttta acatcttttt
     9061 catattccat ttgaactgtc atagcttttc tctcttttct attatttatt gccttttagg
     9121 ctggtttaat aaatttaagt tggattttta atcgcgggta aatccagttg cacccgttcg
     9181 agcaatattg cgaataccgt atgggcgaat gactcgcaat agggcttcgc tcttttctgc
     9241 atttcccgtc atctgaatgg taatcgagct tggcgctacg tctactactg ttgcacggaa
     9301 aggttgaata atcgctaaaa tctcagctct cttctcagct ggcgctgaca tcttaaccaa
     9361 aatcacctcg cgctccaaat gaggcttgtc tgtaatatct cgaatgcgaa tcacatcaat
     9421 ctgacgattg agctgtttga tgatttgctc cacttcatca tgagaagcaa catcaataat
     9481 aatagtgata cgcgatacat tcggatcttc tgttgctcca acagagatgc tttcaatatt
     9541 aacctgacga cgagatagga cacctgtaaa gcgattgagg actcctgaac gattttgtag
     9601 ttttgctgtt aacattctac gcatggaact gcacccccaa catctcatga ttactcttac
     9661 cagccggtac cattggtaac acctgttcct tacgagaaat atctacctca attagcatag
     9721 gaacatcctc agtgatgact tcaaggtctt gagccaaggt ctcaggattg tcaaacttat
     9781 agtttttaat accataagcc tgcgccatca attggaaatc aggaagggta tcaaagaccg
     9841 actctgatgt tctgccttca tagaaggatt cctgccactg gcgaaccatt ccaagtgaat
     9901 gattgttcag cataaccacc ttgattggca ccttgtaaat attcaaaata gccaactcct
     9961 ggttggtcat ttggaaacca ccatccccaa caaacaagac tacttcctta tctgggttag
    10021 caattttagc accgattgct gctggaattc caaagcccat tgttcccaaa ccacctgaag
    10081 tcactaactg acgttcattt tggtagggat aatactgagc tgtccacatt tggtgttgac
    10141 caacgtctgt taccacaatg gcatctccat tcgtcaattc accaattcgt tcaataactg
    10201 cttgcggttg aaccacacgc tctttcttgt catacgaacg aacacgattc ttgtctttag
    10261 tgactttctc aatccacttt tcagtattgt tgtgaactgt tggttctgct agcaacattt
    10321 gcaaggcctt cttagcatct ccaactacag gaatgtctgc actgataatc ttgccaatct
    10381 cagctgggtc aatatcaatg tgggcaacct tagcattctt agcgaaagtc ttaggattcc
    10441 ccgtcaaacg gtcatcgaaa cgagaaccaa tactaatcat aaagtccgct tccgtcatgg
    10501 caatatttgc tgcgaatgac ccgtgcatgc ctcccattcc aagaaagagt gggtgactcg
    10561 ttgcaatcgt tccttgtccc aaaagactgg ttaccactgg aatttgatag cgttctgcaa
    10621 attcatttag ttccgtagca gcctcagcat aactaattcc accaccagct aacaagactg
    10681 gctttttagc cttggacaat tgcttcaaga ttttcttgat ttgcatatca ttcggctcaa
    10741 gagtcggctg ataacttggt aaattcactt ctggtgaata aatgaagtct gtttctaaag
    10801 cagatatgtc ttttggtagg tcaattacaa ctggccctgg acggcctgta gttgcgatat
    10861 ggacagcttc cgtaatgata cgcggaatat cagctgtctc acgaacttgg taattgtact
    10921 tagtgattgg catggtaatt cctacgatgt ctgcctcctg aaaggcatcc ttcccaatcc
    10981 ctgctcgcgc cacctgacct gtaaagacca aaaggggaac gctatcgctc atagcatccg
    11041 caatccctgt aatggcattt gttgctcctg gtccactagt gacgacggca acacccaact
    11101 ttccagttga tttggcatag ccttcagctt catgcaaaca accttgctca tggcgcccta
    11161 gaatgtggcg aatgccttta aaattatata tcgcatcata aaaaggcaaa accgcaccac
    11221 caggataacc aaagatggta tcaactccta aatcacgaag tgtttccaaa actaggtccg
    11281 accccgtctt aggagattct aaactgattt tctccattat tcccctttct ttcctcttaa
    11341 aaataacttg ttactatcat accatttttt caaaattttt caagataaaa gaagaaattt
    11401 tctgaatttt ctattttaac gtttatttat gaatgttatt tttgttttta ttaaaaagat
    11461 accgatttca tttactaaaa agaaaaaaga actgatttct cagtccttca ttaatcttat
    11521 tccacactaa ataggtatgg gtaaacaggt tgttgacctt ggtgaatctc gacttcaacg
    11581 tcttcgaatt cttctacgat ttcttgagcg atttcattgg caagttcttc gcttccgtct
    11641 tcacctacat agaaggttac gatttcactg tcttcatcca acatatgttt caaggtttca
    11701 gtcaatgttt ggtgcatatc agggtttgac acaagaattt ttccatccac catacctaaa
    11761 ttatcgtttt catggatttc taagccatcg atcgttgtat cacgcacggc tgttgtgacg
    11821 cttccgctaa cgacatcgct aagagcagct gtcatacgct cttggttttc ttcaatggac
    11881 ttgcttggat caaaggcaag aagacttgtc ataccttgag gaagagtgcg agcctctacc
    11941 actaccgctg gttgctccaa aacttctgcc gcagattgag ctgccatgaa gatgttcttg
    12001 ttgtttggca agaagatgat gttacgggca ttaacctgtt caacagcctt gataaagtct
    12061 tctgttgaag ggttcatggt ttgaccgcct tcgataacat aatccacgcc ttgagaacag
    12121 aagatatctg ctagaccttt accagccacc acagcaatca aagcatactc tttttcttca
    12181 gccgacttga taacttgagt agcttctttc tcaacctgtg cttcgtgttg gttacgcata
    12241 ttgtcaactt ttaccttgac caagctacca tatttgagac cttcttgcat aacaagtcct
    12301 ggatcttctg tatgaacatg gactttgaca atttcatcat cgttaacaac gaggagagaa
    12361 tctccaagct catccaagta gttacggaat tcatcgtagt caaaatcttt agcataggtt
    12421 ggaccttgct taagagctac catgatttca gtacagtaac caaacgtgat gtcctcagtc
    12481 gctacgtgac cagctacaga cttatgatgc tctacattga tcatctcact catgttggca
    12541 ggagtcgcta caaagtcctc agatgcaata tattcgccag taagggctga aaggaaacct
    12601 tcgtagatga agaccaatcc ttgaccacct gagtccacaa cgccaacttc tttcaatact
    12661 ggaagcatgt ctggtgtttt agctagagct gttttagcac cttccaaggc tgcgcgcatg
    12721 acttcaacag cgtcatctgt ttgctcagct tttttcttag caccgatagc agctccacga
    12781 gaaactgtta aaatcgttcc ttcaacaggt ttcatcactg ccttataggc aacttccaca
    12841 cctgattgga aggccagagc caagtcttga cctgttaact cgtctttatc cttgatagct
    12901 tgggaaaatc cacggaaaag ctgagacgta atcactcctg agttcccacg cgcacccatc
    12961 aaaagccctt tggcaagaat gctcgctact tctccaactg tagaagctgg cttgtctgca
    13021 acttctttag caccattttc aatggtcatt cccatatttg tcccagtatc tccatctgga
    13081 actggaaaga cgtttaatga attgacatat tcagcttgct tattcaagcg agttgatgca
    13141 gcctgcacca tttcttgaaa taagctagta gtaatttttg acacgattat tctcctacaa
    13201 ctttgatatt ttgaatgtag acatttacag tctgagcagt aattccaagc tggttttcca
    13261 agctaaaggc aacacgctct tgaatgtttt ttgacacttc actaatcttt gttccgtagc
    13321 ttaacacggt atatacatca actgcaatac tgccatcttc ggctgccttt acgacgacac
    13381 ctttagaata attttcctta cctagcaggg cttggaaatt atctttgagg gcatttttac
    13441 tagccatacc gaccacacca aaaatctcag ttgctgctcc acctacgacg gttgcaatca
    13501 cttcatctgt tagttcgatt tgaccatctt ttgtattaat ttttacagtc atccttttta
    13561 cctcaactag ttgatactct attttatcat atttcagccc aagtgtaaaa gcagaatgat
    13621 gtatcagcgg atatttactc tatttttcaa acgatgttat acccacaata aaagaaaaaa
    13681 gaccctaagg tctcctttgc ttttattatt aaacgcgttc aactttacat gatttcaaag
    13741 cacgagctga agcccaaact tttttaggtt taccatcgat aagaacagta actttttgaa
    13801 ggtttggttt tacggcacgt tttgtttggt tcatcgcgtg tgaacggttg tttcctgata
    13861 cagtcttacg acctgtaaag taacatactt tagccattgt gttttcctcc tattagatct
    13921 aatatagcgg atgtgctagc accacatacc gtactatgtt atcacacttt cttgtttttt
    13981 gcaagggaat tggaagattt tttatttgtg tcttaaatca ggtcttgcgt gacattttct
    14041 gctctccaca tgccattgtt gattaacaga acaccagaat taaaattatg tgtataaaaa
    14101 tcatctctaa ctgcagctaa gggtatagcc gtcaagtcca aatcccacag ctcatctatc
    14161 gattttctta caacaatatc taaatccaaa tacagtacac gagactcgct tacatacttt
    14221 ggaataaaat atctaaaaaa gccgcatatg aaagtccctc aaaggggaga cgataacctt
    14281 tcagaatact actgtcaatc taaacattca caatctcact attcaaagtc tctagtcttt
    14341 tttccatcaa ttggaaccat tctcgcggaa ggtcatcatt aaaaacataa aacttaagat
    14401 tataatagat gaacacaaag agattttatt gttgtttcaa ctttatccat ataagcatta
    14461 tctgcaccta agacaatcgc ttttttctct tctttcactt tttatctcat ttctttttat
    14521 tcccatcata tgtttctacg taaccattat tttcgcctat tcgttcgtaa aaccatacca
    14581 gtggagattt tagatgaagt cccattacgg tttacaattt ttacattacg acacggagtt
    14641 ttacaaatcg atttcatttg ccaaacgtag ttagtaaggc agttagctag gctacctact
    14701 ttctgctacg acggaaaaat ccacaaatca ataccattcg tggatttttc ctagtgaagc
    14761 gtttaggtaa gccgccatag cggttaccga ttattagatt acgacacgga gtttggcaaa
    14821 tcgattctat ttgccaaacg tagttagtga ggcagttagc tagttcgcca aatagcgact
    14881 agcgtccaac aatttggaac tttagttcca attgttggta ctgagtcaca tcttctcctc
    14941 taactctacg tctggatact tgtccgcaaa ccagcggagg gcaaagtcat tttcaaagag
    15001 aaagactggt tggtcaaaac ggtctttggc taagatattg cgacttgacg acatccgttc
    15061 atccaagtcc tcaggcttga tccaacgaac ggtcttttta cccattgggc tcatgaccac
    15121 ttccgcattg tattcgcctt ccatacggtg tttaaagact tcaaactgga gttgaccaac
    15181 agctcccagc atgtactcac ctgtttggta attcttataa agctgaacgg ctccttcttg
    15241 caccaattgc tcaatcccct tgtggaagga tttttgcttc ataacattct tagcagaaac
    15301 tttcatgaaa atttcaggag taaaggttgg cagtggttca aattcaaact tgttttttcc
    15361 aaccgtcaag gtatccccaa cctgataagt accggtatcg taaaccccga taatatcacc
    15421 tgccacggca ttgatcacat tctcacgact ttccgccata aactgggtaa cattagatag
    15481 tttagccccc ttaccagtac gagggagatt gacactcatg ccgcgctcaa attcgcctga
    15541 tacgatacgg acaaaggcaa tacggtcacg gtgacgagga tccatgttgg cttggatttt
    15601 aaagacaaag cctgagaaat ccttgtcata aggatccaca atttcaccgt ctgttttctt
    15661 gtgaccatgt ggttctggag caaacttgag gaagatttca aggaaggtct gcacaccaaa
    15721 gtttgtcagg gctgaaccga aaaagacagg cgtcaattct ccagccagaa tagcttcctc
    15781 tgaaaactca ttcccagctt catttaaaag ctcaatgtca tccttgactt gctcgtagaa
    15841 aggattgcta ccaaagagtt tgtccccgtc ttctagactg gcaaaacgct catccccttt
    15901 gtaaagctct aaacgttggt tatagaggtc atacaagccc tcaaaggctt tccccatccc
    15961 gataggccag ttcatagggt agctagcaat gcccaagatt tcttccaatt cttgcaagag
    16021 atccaaaggc tcacgaccgt cacggtccag cttgttcata aaggtaaaaa ctggaatgcc
    16081 acgatgtttc acaacctcaa acaatttctt ggtttgagcc tcgatcccct tggcagagtc
    16141 cacgaccatg accgcagcat ccaccgccat caaggtacga taggtatctt ctgagaagtc
    16201 ctcgtgccct ggcgtgtcta agatattcac gcgcttgccg tcgtagtcaa attgcataac
    16261 agatgaagta acagaaatcc cacgttgctt ctcgatatcc atccagtcag atttagcaaa
    16321 agtccctgtt ttcttccctt ttaccgtacc agcctcacga atctcacccc caaagtagag
    16381 taactgctca gtgatggttg ttttccccgc gtccgggtgg gagataatgg caaaggtacg
    16441 acgtttctta atttcttctt gaatattcat aagttctctt tctttgattc tctatttttc
    16501 ttgtttcaat agctgagaat gatttttaca ttggatttta ccattccttt caacactcca
    16561 ttatatcgga ttttagcatt tttttcaatt tctatttctt ttcacttccc cctcccttat
    16621 ttataggaaa atatggtaaa atagaacaga ctaaaaatca tcatttcacg aaaggatgca
    16681 agatgaaaat tacgcaagaa gaggtaacac acgttgccaa tctttcaaaa ttaagattct
    16741 ctgaagaaga aactgctgcc tttgcgacca ccttgtctaa gattgttgac atggttgaat
    16801 tgctgggcga agttgacaca actggtgtcg cacctactac gaccatggct gaccgcaaga
    16861 ctgtactccg ccctgatgtg gccgaagaag gaacagaccg tgatcacttg tttaaaaacg
    16921 tacctgaaaa agacaactac tatatcaagg tgccagctat cctagacgat ggaggagatg
    16981 cctaatgact tttaacaata aaactattga agagttgcac aatctccttg tctctaagga
    17041 aatttctgca acagaattga cccaagcaac acttgaaaat atcaagtctc gtgaggaagc
    17101 cctcaattca tttgtcacca tcgctgagga gcaagctctt gttcaagcta aagccattga
    17161 tgaagctgga attgatgctg acaatgtcct ttcaggaatt ccacttgctg ttaaggataa
    17221 catctctaca gacggtattc tcacaactgc tgcctcaaaa atgctctaca actatgagcc
    17281 aatctttgat gcgacagctg ttgccaatgc aaaaaccaag ggcatgattg tcgttggaaa
    17341 gaccaacatg gacgaatttg ctatgggtgg ttcaggtgaa acttcacact acggagcaac
    17401 taaaaacgct tgggaccaca gcaaggttcc tggtgggtca tcaagtggtt ctgccacagc
    17461 tgtagcctca ggacaagttc gcttgtcact tggttctgat actggtggtt ccatccgcca
    17521 acctgctgcc ttcaacggaa tcgttggtct caaaccaacc tacggaacag tttcacgttt
    17581 cggtctcatt gcctttggta gctcattaga ccagattgga ccttttgctc ctactgttaa
    17641 ggaaaatgcc ctcttgctca acgctattgc cagcgaagat gctaaagact ctacttctgc
    17701 tcctgtccgc atcgccgact ttacttcaaa aatcggccaa gacatcaagg gtatgaaaat
    17761 cgctttgcct aaggaatacc tcggtgaagg aattaaccca gaggttaagg aaaccattct
    17821 aaatgccgct aaacactttg aaaaattggg tgctattgtc gaagaagtca gccttcctca
    17881 ctctaaatac ggagttgccg tatactacat catcgcttca tcagaagctt catcaaactt
    17941 gcaacgcttc gacggtatcc gttacggcta tcgcgcagaa gatgcaacca accttgatga
    18001 aatctatgta aacagccgaa gccaaggttt tggtgaagag gtaaaacgtc gtatcatgct
    18061 gggtactttc agtctttcat caggttacta tgatgcctac tacaaaaagg ctggtcaagt
    18121 ccgtaccctc atcattcaag atttcgaaaa agtcttcgcg gattacgatt tgattttggg
    18181 tccaactgct ccaagtgttg cctatgactt ggactcactc aaccatgacc cagttgccat
    18241 gtacttggct gacctcttga ccatacctgt aaacttagca ggtctccctg gaatttcgat
    18301 tcctgctgga ttctctcaag gtctacctgt cggtctgcaa ttgattggtc ccaagtactc
    18361 tgaggaaacc atttaccaag ctgctgctgc ttttgaagca acaacagact accacaaaca
    18421 acaacccgtg atttttggag gtgacaacta atgaactttg aaacagtcat cggacttgaa
    18481 gtccacgtag agctcaacac caattcaaaa atcttctcac ctacttctgc ccactttgga
    18541 aatgaccaaa atgccaacac taacgtgatt gactggtctt tcccaggagt tctaccagtt
    18601 ctcaataaag gggttgttga tgccggtatc aaggctgctc ttgccctcaa catggacatc
    18661 cacaaaaaga tgcactttga ccgcaagaac tacttctatc ctgataaccc caaagcctac
    18721 caaatttctc agtttgatga gccaatcggt tataacggct ggattgaagt cgagctagaa
    18781 gacggtacga ccaagaaaat cggtatcgaa cgtgcccacc tagaggaaga cgctggtaaa
    18841 aacacccatg gtacagatgg ctactcttat gttgacctca accgccaagg ggttcccttg
    18901 attgagattg tatctgaggc agatatgcgt tctcctgaag aagcctatgc ttatctgaca
    18961 gccctcaagg aagttatcca gtacgctggc atttctgacg ttaagatgga ggaaggttcg
    19021 atgcgtgtgg atgccaacat ctcccttcgt ccttatggtc aagagaaatt cggtaccaag
    19081 actgaattga agaacctcaa ctccttctca aacgttcgca aggggcttga atacgaagtc
    19141 caacgccagg ctgaaattct tcgctcaggt ggtcaaatcc gccaagaaac acgccgttac
    19201 gatgaagcga ataaagcaac catcctcatg cgtgtcaagg aaggggctgc tgactaccgc
    19261 tacttcccag aaccagacct acccctcttt gaaatttctg acgagtggat tgaggaaatg
    19321 cggactgagt tgccagagtt tccaaaagaa cgtcgtgcgc gttatgtatc tgaccttggt
    19381 ttatcagact acgatgctag tcagttgact gctaataaag tcacttctga cttctttgaa
    19441 aaagctgttg ccctaggtgg tgatgccaaa caagtctcta actggctcca aggggaagtc
    19501 gctcagttct tgaatgctga aggtaaaaca ctggaacaaa tcgaattgac accagaaaac
    19561 ttggttgaaa tgattaccat catcgaagac ggtactattt catctaagat tgccaagaaa
    19621 gtctttgtcc atctagctaa aaatggcggt ggcgcgcgtg aatacgtgga aaaagcaggt
    19681 atggttcaaa tttcagatcc agctatcttg atcccaatca tccaccaagt ctttgccgat
    19741 aacgaagctg ctgttgccga cttcaagtca ggcaaacgta atgcagacaa ggccttcaca
    19801 ggattcctta tgaaggcaac caaaggccaa gccaacccac aagttgccct taaactactt
    19861 gcacaggaat tggcgaagtt gaaagaaaac tagacagaac aaaaccagcc ctaaggttgg
    19921 ttttttcttg acaaatagaa agaaaacgtt tgcaatattg cgtgtaaagt ttccaaacaa
    19981 gaaaactaaa aatcgcaaca ataaggagtt atttatatgg ctacaatgaa ggcagctcgc
    20041 tggcatgcag cgaaagatgt tcgtattcaa gaaatagaag ttcctgaagt acttccgcac
    20101 caagtaaaag ttgcagttaa gttcacagga atttgtggta ctgacctcca tgaattttta
    20161 gatggaccta tctttatccc aacagatgag cacgtctatt ctggtcaaaa agcaccggta
    20221 acactgggac atgaattttc tggtgaaatc atagaagtcg gaagcgatgt tacccgtgtt
    20281 aaagttggtg atcgtgttgc tgtggaacca attctagcta aaaataactt agttggtgat
    20341 tataatttgg atccaaacct taattttgtc ggtttggctg cagacggtgg atttgccaaa
    20401 tattgtgttt tagacggtga cttagtacat gtcattccag atagtttgag ctatgagcaa
    20461 gctgctctta ctgaacccgc tgctgttgca gtctatgctg ttcgtcaatc ttctttgaag
    20521 gctggcgata cagctgttgt ctttggttta ggcccgattg gtctattaat tgtagaagct
    20581 cttcgtgcag ctggtgcttc taagatttat gctgttgaac tatcacctga acgtcaagca
    20641 aaagctgaag agttaggagc tatcgttgtc cgtccggaag aaggtgaaac agctgttgaa
    20701 gctattcatc gtttaacaaa cggtggtgta gatgtttctt atgaagtaac gggtgtgcca
    20761 gtagttttag gacaagcctt agctgccgta cataaagcag gtgagtgcat ggtggtctct
    20821 atctgggaac gagaagcaaa tattaatccg aatgaatttg caatccaaga aaagacacta
    20881 aaaggaatca ttgcttatcg tcatatcttc cctaaagtat tagaattgat ggaacaaggc
    20941 tacttctctg ctgaaaaatt agttactaag aaaattaaat tggaaaatat cgtcgaagaa
    21001 ggctttatcg aattaactca agataagtca caaattaaaa ttttggtaga accagaataa
    21061 aaaatcaatc tttttaagac aatactaaca ggtcggagta aacttacttc ggccttttga
    21121 aatataatac tcttcgaaaa tctcttcaga ccacgtcagc gtcacattac cgtatatatg
    21181 gttactgact tcgtcagttc tatccacaac ctcaaaacag tgttttgagc agcttgcggc
    21241 tagcttccta gtttgctctt tgatttccat tgagtatgag aagaaatata gtggatactc
    21301 tttaacatta accactccac ctgactagcc aatattcttt ttcgctccta ccaactccca
    21361 ataactattt tggctttatt tccagagtat tttatggtaa aatgaagagt aataatattt
    21421 attaaagagg taaaaacatg attgaagcaa gtaaattaaa agctggtatg acctttgaaa
    21481 cagctgacgg caaattgatt cgcgttttgg aagctagtca ccacaaacca ggtaaaggaa
    21541 acacgatcat gcgtatgaaa ttgcgtgatg tccgtactgg ttctacattt gacacaagct
    21601 accgtccaga ggaaaaattt gaacaagcta ttatcgagac tgtcccagct caatacttgt
    21661 acaaaatgga tgacacagca tacttcatga atacagaaac ttacgaccaa tacgaaatcc
    21721 ctgtagtcaa tgttgaaaac gaattacttt acatccttga aaactctgat gtgaaaatcc
    21781 aattctacgg aactgaagtg atcggtgtca ccgttcctac tactgttgag ttgacagttg
    21841 ctgaaactca accatctatc aaaggtgcta ctgttacagg ttctggtaaa ccagcaacga
    21901 tggaaactgg acttgtcgta aacgttccag acttcatcga agcaggacaa aaactcgtta
    21961 tcaacactgc agaaggaact tacgtttctc gtgcctaatc tctagaaaga ggtcattcta
    22021 tgggaattga agaacaactt ggcgaaatcg ttatcgcccc acgtgtactt gaaaaaatca
    22081 ttgctatcgc tactgcaaag gtagagggtg ttcactcttt ttcaaacaga tcagtgtctg
    22141 ataccctttc aaaactttca ctcggccgtg gcatttatct taaaaacgtg gacgaagaac
    22201 tcacagcaga tatctatctc taccttgagt acggagtaaa agttcctaag gtagcggttg
    22261 ctatccagaa agctgtcaaa gatgccgtcc gtaatatggc tgatgtagaa ctcgctgcta
    22321 tcaatattca cgttgcaggt atcgtcccag ataaaacacc aaaaccagaa ttgaaagatc
    22381 tatttgacga ggacttcctc aatgactagt ccactattag aatctagacg ccaactccgt
    22441 aaatgcgctt ttcaagctct catgagcctt gagttcggta cggatgtcga aactgcttgt
    22501 cgtttcgtct atactcatga tcgtgaagat acggatgtac aacttccagc ctttttgata
    22561 gacctcgttt ctggtgttca agctaaaaag gaagaactag ataagcaaat cactcagcat
    22621 ttaaaagcag gttggaccat tgaacgctta acgctcgtgg agagaaacct ccttcgcttg
    22681 ggagtctttg aaatcacttc atttgacact cctcagctgg ttgctgttaa tgaagctatc
    22741 gagcttgcaa aggacttctc cgatcaaaaa tctgcccgtt ttatcaatgg actgctcagc
    22801 cagtttgtaa cagaagaaca ataaaaagaa aaagtgtttg atatctatca aacacttttt
    22861 ctttgcctcc cactatctaa aaaaatgata atagatataa ttgtaaacaa aaatccagat
    22921 aggttttgca tgattgagaa agttaaaaaa actatggcag agaatcgtta atctcagatt
    22981 gtcggtagaa cgataaacaa gggcaaaaaa gaaaccaatc agactataat ataataaact
    23041 aattggatct ctgtgagata gtatcaaatg actaagccca aagataaggc ctgataagat
    23101 gacatctaaa taatacttgg actagggaaa gaaggtattc ataaaatacc ctctatcaag
    23161 agtctcctca aaaacaggac cgatgattac aggcaggaca aaagataaga tagtcgataa
    23221 aaaggttggt tgtccatttg aaagaaccac ggtaaaatac tcatcatgaa tattcctatg
    23281 attaatcaaa tgagcatagc gtgcccaaaa attaccgaga atctgataaa ccacataagt
    23341 tgcaaataag gagaagacaa atgaccagtt ccagctcttt ttctcaaaga taaagagcat
    23401 ctttttcttt tttaacctcc aaattaatag aaaaggaaac ttcccactaa tcccactgtt
    23461 aaaataagag aatagacatc agctcctaac cctaaaatga tcgtcacata caatccaatt
    23521 gtttgtggta aataggtaga tagtaaaata ataagcaaaa atattccaaa ttgtcttagt
    23581 ttctttgtgt ttctcatcgt acttttttga aagattaccc tgttcggaag ccgtacttcc
    23641 aagcatctat ataagaatta agtgcccctt gcctcatata aggagcaaat tctctataat
    23701 ataaccatct actatatcca tcttcccaaa cagcaagacc acctgaagtt tgctccaagt
    23761 cctcagttga aagaactgta aatgtatttg tacctgtcat tgcaagtacc ttcttaaaat
    23821 atagtgattt gaaataagat gtgaacaact ctatcaggaa agtcaaatta atttatagaa
    23881 atattttagc agccaaggtg tactgttata gattcaatac actataaatt tttgtaagct
    23941 tacatctaca gtatacatct tttttgtcta ttttatagcc catctcctca actgtcaatt
    24001 tttcaacctg aattgcattt ttccataaaa aatgagacct ttctagtctc atttagtcat
    24061 tcttagtatt ttctaaatcg ttgatagcgt tcttccagca actcttctag cggtttttgt
    24121 gaaagtctag ccagctccgt ttggagttct tttttgacac tcttaatcag ttctttacta
    24181 gaaagtccta cttcagaaat caccttatcc accacgtcca tttctaacag ttcatgcgaa
    24241 gtgattttca tcagttctgc tgcttccatg gcgcgagtac cgtccttcca taaaatggaa
    24301 gcaaagcctt ctggactgag aatggcatag atagaatttt ccagcatcca gacacggtcc
    24361 gcgacagcta gagccagagc cccgcctgaa ccaccttcac cgataataat ggcgataata
    24421 ggaactttca ggtcactcat ttccatgaga ttgcgagcga tagcttcccc ttgaccacgt
    24481 tcttctgctc cgacaccagg ataagcacct gctgtattaa taaaggtcac aactggacgg
    24541 ccaaatttct cagcctgttt catcaaccgc agtgcctttc ggtagccttc tggatgtggt
    24601 tggccaaaat tccgtttgag gttgtcttgc aaactcttgc ctttttggat accaacaact
    24661 gttacagctt ggtctccaag ccaaccaata ccaccaacaa ctgcaccatc atcacgaaaa
    24721 gaacggtcac catgtaattg gataaattca tcaaaaatgc ctgtcgcaaa gtccaaggtt
    24781 gtcaagcgac tctgctcacg cgcttctctg actatttttg caatattcat ctaggactcc
    24841 ctccatgcaa tctgactagg ctagcaatcg tatctggtaa gtctcttctt ttgacaatag
    24901 catccacaaa gccatgttct aataggaatt ctgccttttg gaaatcctca ggcaagcttt
    24961 cacgaaccgt attttcaatc acacgacgcc cagcaaaacc aaccaagctc tgtggttcag
    25021 ccagaatgat atcgccttcc atagcgaaag aagctgtcac accaccagtc gttggatctg
    25081 tcaaaatggt caggtaaaag agaccagcat ttgaatgacg tttaaccgcc gcagagatct
    25141 tagccatctg catgagactc atgattcctt cctgcatacg ggctccacca gaggctgtga
    25201 ataggacaac tggcaatttt tcgacagtcg catactcaaa caaacgagtg attttttcac
    25261 ctacaaccgt acccatagaa gccatgataa agttagaatc cataatccca agagccacag
    25321 tctgaccttt aataagagca gttcctgtca caacggcttc atgcagacct gttttttcac
    25381 gcatagatgc cagtttcttt tggtaaccag ggaaatgcaa gggatccttg ctttcaatcc
    25441 ctgtaaacaa ttctttgaag gttcccatat caatcgtcaa agccaagcgt tcttgggcag
    25501 aaatacgaaa ggtatagcta cagtgcggac agatacgttc acttcccaga tccttctgat
    25561 agatggtatg cttacagcct ggacactggg aaaataattc atctggaacc tctggcttag
    25621 cttgaggttt ttccctaacc gaacgattgg gattgattcg aatatactta tcttttttac
    25681 taaatagagc cattgattcc ccttttcggt ttaaactctt aaagtcattt tattcttttt
    25741 cttgatattt aggtaagaag gtttccatca agaaggaagt atcataatcc ccagcaatga
    25801 cattgcgatc tgaaatgagg tcaagctgga aatctgcatt ggtctgcact ccttcaatct
    25861 ctaattcata gagggcacgt tgcattttca tcaaggcgtc aaaacgattt tcgccgtgta
    25921 ctatgatttt ggcaatcata ctatcataat aaggcggaat ggtataacct ggataaactg
    25981 ctgaatccac gcgcaagcca actccaccac ttggcagata gagattagta atcttacctg
    26041 gacttggagc aaagttaaag gctgggtttt ctgcattgat acgacactcg atggcatgac
    26101 cgcgtaggac aatatcttct tgcttaacag acaaaggctg acctgccgca atgcaaatct
    26161 gttccttaac gatatcaaca cctgaaacaa actctgttac tggatgttct acctgaacac
    26221 gagtattcat ctccatgaaa tagaaattgc tacttgcttc atcaagaaga aattcaatgg
    26281 ttcctgcatt ctcatagcca acaaactctg ccgctcgaac agcagcagca cctatttcat
    26341 gacgcagcgt ttttccgatt gcaatcgagg gactttcttc caaaaccttt tggttattcc
    26401 tttgaagaga acaatcccgc tcacccaagt gaatcacatg tccatgctca tcacctagga
    26461 tttgaacctc aatgtgccga gctggataga taacccgttc tatgtacatg gcaccattgc
    26521 cataattggc cttggcctca ctagaggcag tttcaaaggc agaaacgagg tcatctggtt
    26581 tttcaacctt acgaatccct ttaccacctc cacctgctga agccttgagc ataacaggat
    26641 agccaatttt ttcagcaaca atcaaagctt cttcagagtt atgcacttct ccatctgaac
    26701 ctggtataac aggcacacct gctttaatca tctgagcacg cgcattgatc ttatccccca
    26761 tcatatccat aacatgacca gatggaccga taaacttgat acctacttct tcacacatgg
    26821 tcgcaaattt ggaattttca ctgagaaatc caaaaccagg gtgaatagct tctgcctcag
    26881 tcaagactgc agctgataga actgcattaa tattgagata agactctgtt gccttgccag
    26941 gaccaataca aactgcttca tctgccaaaa gcgtatgaag agcttcctta tcagcagttg
    27001 aataaaccgc taccgtcgca atccccaatt cacgtgccgc acggataata cgaaccgcaa
    27061 tttcaccacg attggcaatt aaaatttttc gaaacatgga gaacctcctt agttcccaat
    27121 tgcaaaagta aggataccac tggctgcaag cttgccatcc acttcagcct ttgcttcaac
    27181 cacagctatg gtgccacgac gttttacaaa agtcgctgtc ataaccaatt ggtcgcctgg
    27241 tacaacttgc ttcttgaact taaccttgtc cataccagcg taaaagacca gttttccttt
    27301 attttcaggt tttgataact ccaacacacc agcagtttgc gccaaggctt ccataatcag
    27361 aacacctggc ataactgggt attgaggaaa gtggccgtta aagaaaggtt cgttaatggt
    27421 cacatttttg atagcaacaa tggtatcctc gctcacttcc aagacacggt ccactagaag
    27481 cataggataa cggtggggaa gagcttcttt gattccttga atatcgatca tttgatacgt
    27541 accaatcctt taccaaactc aaccatttct tcgttagaga cgagaatttc cgttaccaca
    27601 ccatccttag gagctgggat ttcattcatg actttcatgg cttcgataat taccaatgtt
    27661 tgaccttttt tgacactatc accaactgta acgaaggcag gtttatctgg tccagcagcc
    27721 aagtaaacca ctccaacaag tggactctct acaagatttc cctcagtagc cacacttgct
    27781 tcagctggag ctggaacttc ttctgctaca gtctctgctg gagcagatgt aggagctact
    27841 ggactcggtg ttgctagaac gggtgctgga gcgacttgag ttgcaacttc aggcacaggt
    27901 ctcgcttcat tcttgctaaa ctgcaactca tccgtcccat ttttataaga aaattctctc
    27961 aaacttgact ggtcaaattg agtcatcaag tctttaatat cgtttaaatt catacttatc
    28021 tattctccca acgtttgaaa gcaagaactg cattgtggcc tccaaaacca aaagtatttg
    28081 aaatagcgta tggaatttct ttctccaagc cttgtccata aacgacatta gcttcgatat
    28141 aatctgatac ttcacttgtc ccagctgtca ttggtacaaa gttatggcgc atagcttcga
    28201 tggtgacgat agcttctact gcacccgcag cccccagcaa atgtcctgta aaagacttgg
    28261 ttgatgatac aggtacttcc ttaccaagaa cagctacgat agctccactt tctccttttt
    28321 cattggcagg agttgacgtt ccgtgagcat tgacataggc tacttgctct ggagaaatct
    28381 cagcttcttc caaggctagt ttgatggcct tgatagctcc ctgaccttct ggatgtggag
    28441 aagtcatgtg gtaggcatca caagtatttc cgtaaccaac cacttcagcc aggatagtag
    28501 ctccacgttt ttcagcgtgt tcaagacttt ctaaaaccaa catccctgaa ccttcaccca
    28561 taacaaaccc attgcgatcc ttatcaaatg ggatcgaagc acgagttgga tcctctgtag
    28621 tagagagagc tgttaaggct tggaaaccag cgatggcaaa aggtgtgata gaagcttctg
    28681 ttcctcccac caacatcaca tcttggaaac caaacttaat ggagcggaag gcatccccaa
    28741 tcgcatcatt tgatgaagag caggcagtat tgatagattt acaaacaccg tttgcaccaa
    28801 aacgcatggc tacattccca gaagccatat ttggtaaagc ttttggaaga gtcattggtt
    28861 tgacacgttt gggtcctttt tcatgaaggc gaagtacctg atcttcaatt tccttgattc
    28921 caccaatacc agatgcaacg ataacaccaa aacgatccct attaagagcc tctacatcaa
    28981 gattggcatg gtttacagcc tcttgggctg catacaaggc atataaagaa tagttatcaa
    29041 aacggttggt atcttttttt acaaagtatt tatcgaacgg aaaatcttgg atttctgccg
    29101 cattatgcac atcaaagtca ctatgatcaa attttgtaat gccaccaatg ccgattttcc
    29161 cagttgctaa actattccaa aattcttctg gtgtatttcc gattggagat gttactccat
    29221 aacctgttac cactactcga tttagtttca ttcttttcac ctctagcttt cgctacatac
    29281 ttaagccacc atcaatggca atcacttgac cagttagata atcttggcct gctaaaaata
    29341 ctgtcaaatc tgcaacctgc tctgcctgcc caaattcttt catcggaatc tgagctagtg
    29401 tagcttcctt aatcttatct gataagatag ctgtcatatc agactcaatc attcctggag
    29461 caatcacatt gactcgtata ttccgactag cgacctcgcg tgccacagac ttggtaaagc
    29521 caatcaagcc agccttagaa gcagcatagt tagcttgacc aatattcccc atcaaaccaa
    29581 caacactaga catattaatg atagcacctt ctctggcttt catcatcggt ttcaagactg
    29641 attgtgtcat attaaaggca ccagtcagat tgaccttgag cactttttca aaatctgctt
    29701 ctgtcatctt gagcataaga gtatcttggg taatccctgc attgttgacc aaaacatcta
    29761 ctgaacccag ttctgcaata gcttgatcaa tcatacgctt agcgtctgca aaatctgata
    29821 catctcctga aatgggaacc accttgatac catagtttga aaactcagcg agcaattctt
    29881 ctgagattgc cccacgactg tttaagacaa tgttggctcc tacttgagca aacttgtggg
    29941 cgatggcaag accaattcca cgactcgaac ctgtaataaa gatattttta tgttctagtt
    30001 tcattttttt cctttcaaaa cttctactta ttttagtcta tttttctaaa agtgctacta
    30061 aactcgcttg atcttccaca tgagctaagt gagcagtttg atcaattttt ttaacaaaac
    30121 ctgacaagac tttccccggt ccaatctcga taaagttgct tatgcctgct tcttgcatga
    30181 ccccaatact ttcatagaaa cgaacgggtt ccttgacctg acgcgtcaag agctgagcaa
    30241 tgtcctcttt ttgcatcaca gcagcttctg tattgccgac taggggacaa gtaaaatctg
    30301 aaaaacttac ctgagctaga gtttcagcta gtttctggct agcaggctca aggagagcgg
    30361 tgtgaaaggg acctgacacc ttaagaggaa tcaagcgttt ggcacctgct tcttgcaaaa
    30421 gttcaaccgc tcgatcaact gcaaccactt ctccagcaat gacgatttgt gcaggtgtgt
    30481 tatagttggc tggagtaacc actccaagtt cagaagcttt ttgacaggct tcttcaatga
    30541 cctctactgg cgtattgaga actgctacca tcttgccaga gtcagcagga gccgcttctt
    30601 ccatataggc tccacgctta gctaccaagg caaccgcatc ttcaaaatcc aaggcgccgc
    30661 ttgccaccaa ggcagagtat tctccaagag acaaaccagc aaccatatca ggctgatagc
    30721 ccttttcttg caataaacgg tagatagcaa ccgaagtcgc tagaatggct ggttgcgtat
    30781 agcgggtctg attgagtttg tcttcttccg tatcgatgag ataacgtaaa tcataaccga
    30841 gcacctgact cgctcgatca atcgtttctt tgacaatcgg atactgatca tagaaatccc
    30901 ttcccatccc tagatactgg gcaccttgac cagcaaataa aaaggctgtt ttagtcattt
    30961 cttacaactc ctgcccagcg agaggcttct tcttgaattt tcttagcggc tccgtaatac
    31021 aaatctttta ggatttcttc agctgtttct tctttagaaa caagccctgc gatttgacct
    31081 gccatgacag agccaccatc cacatcaccg tgaacaactg ctttggctag ggcacctgct
    31141 cccatttgtt caaagatttc taaatcagga tcttcctgct taaaggcatc tttttcagcc
    31201 agttcaaaat ctctagtcaa ctgattttta atagcacgaa cagcatgacc aaagtgctga
    31261 gctgaaatcg tagtatcaat atcccttgct tttaaaattt tctccttgta gtttggatgg
    31321 gcattcgact cttttgcaac tacaaaccgt gtccccacct gtacagcctc tgcacctagc
    31381 ataaagccag ccgcagcacc ttcaccatcc gcaattcctc ctgcagcaat aacaggaata
    31441 gatatagctg tggctacctg tcgcaccaag gtcatggttg ttaatttacc gatatgcccc
    31501 ccagcttcca ttccttctgc aataacagcg tctgcaccga ttttttccat gcgtttagct
    31561 aaagcgacac taggaacaac aggaataacg attatcccag cttcatggaa acgttccata
    31621 tacttgcttg gatttcctgc tcctgttgtg acaactttaa caccttcttc aataacgaga
    31681 tccacgatat cttccacaaa gggagataag agcatgatgt tgaccccaaa gggtttatca
    31741 gtcaatgatt tgattttatc aatattggcc ttgacaactt ctttcggggc atttccccca
    31801 ccgataattc ctaatcctcc agccttggaa acagcccctg ccaaatcacc atcagcaacc
    31861 caggccatcc ctccttggaa aataggatag tcaatcttca ataattctgt aatacgcgtt
    31921 ttcatagtgc ctccaacctt ccttgcttac gtaatagttc gatttcacca taatttgaca
    31981 gtcaaactat tacctaaaca agagggagtg ggtttctccc tactccttct actaatattc
    32041 tgcttatttt gcttgctctt caacgtaagc aaccaagtca ccaactgttt tcaagtcatt
    32101 ttctgcttcg atttggatat caaaagcatc ttcgatttct gagattactt ggaacaagtc
    32161 caatgaatct gcgtccaaat catcaaaagt tgattcaagt gttacttctg atgcgtcttt
    32221 tccaagttct tcaacgataa tttcttgtac tttttcaaat actgccatga taggactcct
    32281 ttaaaataaa tagttttttt ataacaatgt gttcaccaca tgattaccta aattgtaaga
    32341 atgagcgtgc cccaggtcaa gcctccaccg aagcctgata gaagaacagt ctggctacca
    32401 tctaaaggga tgagaccttg ttctacacac tctgaaagta aaatcgggat actggctgca
    32461 ctggtattgc catattccat catattggct ggaagtttgg ctcggtcaac accaattttt
    32521 ctagccatct tatccaaaat acggtcattg gcttgatgaa gtagcagata atccaagtct
    32581 gtcacctcta taggagattc atcaatagtc tgcttgatag acttggctac atctcgaatg
    32641 gcaaaatcaa agactgtgcg tccatccatc ttcaaaaacg aatctgcact ttcttgatct
    32701 gaaaatggag aatgcaaacc tgaatgccca taagttaaac actcgctgcg acttccatcg
    32761 ctattgagac tctcagctaa gaaatgctct tgctcgctag cttctaacaa gacaccacca
    32821 gcaccatctc caaacaacac agctgttgat cgatccgacc aatcgactgc cttagagagg
    32881 gtttcactac caatcaccaa gcctttttga aagcgaccag aagcgataaa cttttcagca
    32941 gttgaaagag caaatacaaa tccactgcaa gccgcggtta agtcaaaagc aaaggcttta
    33001 ttagcgccaa tattagcttg aacacgagca gctgtagagg gcatcatcga atctggagta
    33061 atggtagcta ggatgataaa atccagttct tttcctgtta ttccagcttt tgccatcagt
    33121 ttcttagcaa cctctgtagc caaatcactg gtagattctg ttcttgaaat atgcctttgt
    33181 cgtattcccg ttcgacttga aatccactca tcattggtat ccataatctg agccaagtcg
    33241 tgatttgtaa ccacttgctc tggcacataa tgagcaacct gacttatttt tgcaaaagcc
    33301 attatttcaa atcctccaaa aattggtaaa gattagtcaa acctttaccc atgacagcaa
    33361 tttcttcctc gctcatgcca tcaataattt tttctaccat ggccttgtgg aagcgtttat
    33421 gcagcctatg aatcaagcga cccttctttg tcaaatgcag atgcaccaca cgacgatcct
    33481 gttctgaccg aactcgctca atgtagccct tacgctctaa attgttcaaa cttgtcgtaa
    33541 cagttccaag agttaccatc aactcttttg acacttgact tggagtcacg tctggagcct
    33601 taccgatgac atcaatcgta tgcatttctt tgatggagat atccttaaaa cgactacctc
    33661 tcaagttcac ttcctcaatt acaaggacat tgttaaatat agatgttaaa tattcattga
    33721 ttcgttggta gtccattttt catatccctc cttcttcaaa aaacttttac aatcaaaaca
    33781 tttgacagaa agaattatat caaaattcaa agaatgatgc aagtattttt tattttcctg
    33841 taaatttagg tcttcttctc tccgaatgag ctcgcactcc ttctttgaaa tcctctgttt
    33901 gagctaagga tttctgtagg ttcagttcta aagtagcgta accctgccag tctttaaatt
    33961 ggctctccca aaccaacttc ttaatggcag cataggaatt acttgaaaca cgtcttaatt
    34021 ttttaagaag ctgttctctc gtcttttcaa gtttttcagc ttcagaaacg cggtaaacca
    34081 acccccattc tagggctttt tctgccgtta aagcctctcc tgtcatagct aattgagcag
    34141 cacgcgtcac accgatactg cggctcaaga gatgaattcc ccctgcatct ggagccaaac
    34201 caacaccaac aaaggcttgg ataaacttag ccttatccgt cgccaaacag aaatctgccg
    34261 caacagccat attcgctgcg gcacctgcaa cagcaccgtc aacttccatt aaaacaggtt
    34321 tggctatttg cttgatttta taagaaatcg tattgaccaa ctctgcgatt tttgtcaatg
    34381 atggaatatc atcctcatcc actgcccgct tcatctctac caaatctccc ccaactgaga
    34441 agacctttcc attggcattg attaagataa aatgcacagc tggattttct tctgccaaag
    34501 tcagagcttc taaaatctcc tcacacatgg gaatatgaaa accatttgcg acctcaggac
    34561 ggttcaaggt aaggattgcc aagtcctctt caagctgata aataatgtgt tccatcaggg
    34621 ctccttttta ttttataagc agtttatact cttcgaaaat ctcttcaaac cgcgtcagct
    34681 tccatctgca acctcaaagc agtgctttga gctgacttcg tcagtcttat ttacaacctc
    34741 aaagcagtgc tttgagcagt ctgcggctag cttcctagtt tgctctttga tttcattgag
    34801 tgttaaatta tttcactgtc aaagtatatc ttttttagga gcagaaagca agaaaaaatc
    34861 gactgaaagt gtctcagccg ataagaaagg ctcgctttag gctagaaagc atcttatttt
    34921 cttcattgaa aaaagccttt ctttctgcta taatcgtata aaatacttac tttaggagtt
    34981 cttatgaaag ttgttaaatt tggaggtagt tctcttgcct ctgctagtca attagaaaaa
    35041 gttttaaaca tcgtcaaaag cgattcagag cgtcgttttg tagtcgtttc tgcgcctggt
    35101 aaacgcaatg ctgaagatac taaggttacg gatgccctga ttaaatacta ccgcgactat
    35161 gttgcgggta acgatattag caagagccaa agctggatta tcgaccgcta tgctgctatg
    35221 gttagtgaat tgggactaaa accagctgtg ctagaaaaaa tttctaaaag cattcacgcc
    35281 ttggccactc ttcctattga agaaaatgaa tttctctacg atactttcct agcagccggt
    35341 gaaaataaca atgccaaatt gattgctgcc tactttaacc aaaatggtat cgatgcacgc
    35401 tatatgcacc ctagagaagc tgggattgtg gtcacaagtg aacctggtca cgctcgcatc
    35461 attccatcaa gttatgacaa gattgaagaa ttgacaaaca ccaatgaagt ccttgtcatt
    35521 cctggtttct ttggtgtcac taaggaaaat caaatctgta ctttctcacg tggaggatct
    35581 gatattacag gttctatcat tgctgctggt gtcaaagctg acctctatga aaactttacg
    35641 gacgttgatg gtatctttgc agcccaccct ggtattatcc accaaccaca ctcgattcct
    35701 gagttgacct accgtgaaat gcgcgagttg gcctatgcag gcttctcagt ccttcatgac
    35761 gaggctcttc ttcctgccta ccgtggaaaa attcctctgg ttatcaagaa taccaacaac
    35821 cctgaccatc caggtactcg tatcgttcta aaacacagta atgatgaatt tccagttgtg
    35881 ggaattgctg gtgactcagg ctttgtcagc attaatatgt cgaaatacct catgaaccgt
    35941 gagattggat ttggccgcaa ggttctgcaa atcctggaag aacttaacat cggttgggaa
    36001 catatgccaa caggtatcga cgatctttct atcattctcc gttctcgcca actaactccc
    36061 atcaaggaag aagaaatcct gcgtcagttg gttcaaaagg ctaaagtaga tcatgcagaa
    36121 atcgaacacg acctttctat cattatgatt gttggtgaaa aaatgaagag ccatatcgga
    36181 gtgactgcta ctgcgacacg cgctctatct gaaaacaaaa tcaacatcca gatgatgtct
    36241 caaggttcta gtgaagtttc tattatgttt gttgtcaata aagaccaaga gaaagcagca
    36301 attaaagccc tctacaatgc cttttttgga gaaagtaagg aagactaagc atggcccaat
    36361 cacttaacaa aacagtactc ctcagtacga caggcacttc ctacctctct atcgctggga
    36421 aagttgggaa attccttgtc ggagatcagg ctttggaatt ttacccagat gtcaatgtcg
    36481 aacaatttat ccagattcct tggagccata tcaatcagat tggagccaat gtcactggac
    36541 gcaaaatcag ccgccacttc gaagtcttta cagacaaagg aaaattcctc tttgcttcaa
    36601 aagactcagg tgccattctc aaaattgcac gcgaaaaact aggcaatgac aaggtcgtca
    36661 aacttccgac cctgattcag acaattagcc aaaaatttaa aaatctattt gcaaaaaagt
    36721 agaaacttta gtataatcat agcaacggat aagtaggtta tcttcttctt tcagaaagtc
    36781 tgcgggtgct gcgagcagaa taggagggat aggtgaaatt ctaccgttag tgacaattac
    36841 atacacaatc aagtgcacac ctgtgaagtt ggatggaacc gtggccctgc cactccaacg
    36901 ttttgtcagg gtgctttttt cataaaggag ttcttatgtt agatatcaaa cgtattcgta
    36961 cagattttga agctgtcgca gaaaaattag ctacacgtgg tgtagatgct gctgtcttga
    37021 atgaaatgaa agaaatcgat gctaaacgtc gtaacatctt ggtcaaggtt gaaactctca
    37081 aagcagaacg taacacagtt tctgctgaga ttgcccaagc taagcgcaac aaggaaaata
    37141 cagatgacaa gattgctgcc atgcaaaatc tatctgctga ggttaaagcc ttggatgctg
    37201 aattggcaga aatcgatgct aaattgacag aatttacaac gactcttcca aatatcccag
    37261 ctgacagcgt tcctgttggg gctgacgaag acgacaatgt ggaagttcgc cgttggggta
    37321 ctccacgcga gtttgacttc gaacctaaag ctcactggga tctcggtgaa gaccttggta
    37381 tccttgactg ggaacgcggt ggtaaggtaa caggcgctcg cttcctcttc tataaaggcc
    37441 tcggtgctcg tttggaacgt gctatctaca actttatgtt ggatgaacat ggaaaagaag
    37501 gctatactga agtcatcaca ccttacatag tcaaccatga ttctatgttt ggtactggtc
    37561 agtatccaaa atttaaggaa gatacttttg aactcagcga taccaacttt gtcttgattc
    37621 caactgctga agttcctctg acaaactact accgtgatga aatcttagac ggcaaagatc
    37681 ttccaatcta cttcactgct atgagtccgt cattccgttc tgaggctggt tctgccggtc
    37741 gtgatacgcg tggcttgatc cgtttgcacc aattccacaa ggttgaaatg gtcaaatttg
    37801 ccaaaccaga agaatcttac gaagaattgg aaaaaatgac agccaacgct gaaaacattc
    37861 ttcaaaaact caaccttcca taccgtgtcg ttgctctctc tactggagat atgggcttct
    37921 cagctacgaa gacttacgac ttggaagtgt ggattccagc acaaaacaat taccgtgaaa
    37981 tctcaagctg ttcaaacaca gaagatttcc aagcccgtcg tgcccaaatc cgttaccgtg
    38041 atgaagcaga tggcaaggtg aaactccttc ataccttgaa cggttctgga cttgcagttg
    38101 gacgtacagt ggctgcaatt cttgaaaatt accaaaatga agatggttct gtgaccatcc
    38161 cagaagcact tcgtccatac atgggtggag ctgaagtcat caaaccataa aaaataaggt
    38221 ttagctattt ctagctagac cttttttcgt aaccaaatca gataagcacc tagtacacag
    38281 aataaaatag ttaggcatat aatggtttca gccaatacca ggtaatccag aaatggaagt
    38341 ttcaaaattc cctgagccat cttgagcgag gtcgctgtga taatggttgg gaaggtgagg
    38401 gctgagaagg ctggttgaaa accttgtttt aaaatgttgg gcagacgagt taaaacaaag
    38461 aaaaagaagg attgagaagc caaaatcatg acaatcaaga cccaagtcgg caggctggtt
    38521 cctcctactc gaactagaga agccaagagt agagagaaag gagcacagta gattccttct
    38581 tgtccaagca aggctagtgg gagtggatgt ttctttaaat cgctataaat aaggggatag
    38641 agatagaagg tcaagagaaa accaaaactc aaggtcgcat aggcaatttc gataatacct
    38701 accagaggat aggtcaaggc agccactgct atccccacat agagaaccgt ccaacttgga
    38761 gtggcatgaa ccctccgccc tggacaagca aacttgatgg taaaaccagc aatcaaggtc
    38821 aaatccaaga gaaatgaaaa ccaccaaatc ccttgtgcta ccaaaggaag ataagagaat
    38881 acgcgaaaga cataggtcga taaaatcatc ccagccatag gaaaggttgc cattcctgac
    38941 aaaagagggg gcttggtcaa ttcttgcttg gtttctttcc aattaaagag atgcagaatt
    39001 agaaagtaaa tccataaaac caaaccagtc agactaaaaa gatgggatag aaccggcaac
    39061 gtatctaaaa taagatttcc agctcctgcc aaacctagca aacaacctga aaatactaag
    39121 gggagttttt tcatcctaac ctccaataat catgttagtt tcagtataac ataaaagcgc
    39181 ttaaatgagg atttaaaaaa acgaagtccg cttatttcag acttcatttt actcagatat
    39241 gaattaggca taaggttgca attctggatt aattggtgta ttagctaagt tgttggcata
    39301 gttacagagg attgctaggc tgacaccaaa aaccacatcc aaggcatttt gttgagtgta
    39361 gccagcttct aaaaactcag acaaggcttc atctcctaca cgacccttgg tattgataac
    39421 tgccaaggta aacttagcta gggtatccaa tttaggatct gtttcaattg gagtacgatt
    39481 gcgaagagct tgaatcaagt catcattcat ctggatttgt ttgatggaaa aggctgtgtg
    39541 acctgcgaca cagaaggcac aaccattggt cacggctgcc gtgatttgca ccacttcacg
    39601 ctcaacgggt gtcaggctgt tgcgacggtg gatagatgag acaatttggt aggcttctaa
    39661 aacagtcggg gcattggcca agagaccgat taggttggga atatagccat tgttgtcttt
    39721 ttctactgtt tcaagaattt ctttcacttc tgctggtgct gactctactg tatggatagt
    39781 aaatgttgtc ataagatacc tcttttctta ttattgacac taatattatt ggaaaatctt
    39841 ataaaatcct gattcctaag tttatctaag ataaagcttt attctctcat aagattttcg
    39901 ttgttatatt agtttatcac acttccaatc acttgcataa tatatattat atatcaggct
    39961 gataaaaatt atttataggc aaaaaaatca cacgagctgt gtgattccat tatttgtcaa
    40021 aatacttttt agtttcagca ataacgactg gcgacaagac caagagggca atcaagtttg
    40081 gcagaaccat caaggcatta acgatatctg cgataatcca gaccatatcc aactcgataa
    40141 atcctcctaa caagaccatg agcacaaaaa ccacacggta gagccagata aagcgaaccc
    40201 caaagaggaa ctcaaaacag cgttctccgt aatagttcca acctagaatc gttgtaaagg
    40261 caaaaagtac aaggaagatg gtcaagaggg caggcccaaa gtgtgaaaag actgttgaga
    40321 aagctgactg agtcaaggca accccattca agtcaccact ccaaactcca gttaccaaga
    40381 tggtcaaacc agttagagta caaatgatga gggtatcaat aaaggttcct gtcatggaaa
    40441 tcaaaccttg ctctactggt tcatttgtct tggcagctgc agctgcaata ggagcagaac
    40501 ccagaccaga ttcgtttgag aacacaccac gcgccacacc attttgaata gccatccgaa
    40561 cgctagcacc agcaaatcca cctaccgcag caaggggact aaaagctgag gtaaagacta
    40621 aagcgattgt gccagggatt tttccgatat taaagaaaat aactgtaaga gttcctaaga
    40681 tataaatgat ggccataaaa ggaacaacag tagttgaaac cttagaaata gacttgagtc
    40741 caccaaagac tgcaatcgct acaaagacag acaagacgag agctgtgatg gctggcgaaa
    40801 tcgtcgttgt attttggata gattctgcaa tcgagttgac ttgggtgaag gttccgattc
    40861 ccaagagagc aaccaatact cctgctactg caaacaaaac agcaagtggt cgccactttt
    40921 ctcccatccc tagaaggata tagtgcatgg gacctcccgc tactgcacca tggtcgtcct
    40981 tggtgcggta tttgatggcc aagagtcctt ccgcatactt ggtagccatt ccaaagaaag
    41041 ccgccatcca catccaaaat agagctcctg gtccaccaac cttgatagcc gtcgcaactc
    41101 ctatgatatt tcctgttcca acagttgatg ccaaggctgt acacagagct gcaaaactgg
    41161 atacatcacc atgtccctta tcctggataa aaataagctg aaaggccttg ggcagacgca
    41221 aaacctgcaa gagtcctagc cgcatggtta ggtaaatccc tgttccgacc aataaaatca
    41281 agaggggcgg tccccaagca aaagcatcga ttgatttaag caattctaac attttcttct
    41341 cctatcgttt caaccccaaa agaaagagca catgcaagat acatgtactc tggaatgctt
    41401 agataaatgc taaaaagcgg tctatcctag ctctgtcctt ttacctgaga gtttgagcag
    41461 ttgcctgcct tgccccttcg gtgcctttac ggtctctcca gagttccgtc catttacagt
    41521 catggaaaat caaacgattc cccacttcta ttaaacttca ttcggtgttg gtatttaatt
    41581 gattctaatt ttacaaaaaa tgttggcttt tgtcaatgtg tttattagta aaaattagtt
    41641 caacagtttt tactttataa agtccagaat actgctatcc tttaaaagtg acaatagtcg
    41701 caccactgcc tccagcattt tgtggggcat agccgaaact cttgacatgt ttgtttcttt
    41761 gcaagtattt ggtaactcct tcacggatga ctcctgttcc gataccatgg atgatatcaa
    41821 cttgagccat attgttaagc aaggcttggt cgatgaaggt atctagctca ttcatggctt
    41881 cttcatagcg cttgcctcga agatccagtc tagcttgagg tcctcgccca gaagttcgtt
    41941 tcacaacatt gacctgtttc ttcttgactg gtttttcttg ctgggcttga acaagatcaa
    42001 actctttctc ttccaaggtc atcttaatca agccaacttg ggcttcccag cgaccgtcct
    42061 tgagttgact ggtcaaggta ccacgctgac cataactgag aaccacgata tcatctccca
    42121 cctttggagc tcgttttttc ttggcctttt gaaggacctt atttttagac aagtccactt
    42181 tttcaggagc caattttttc aacttggcct tggcttcaat gatttcgtgg ggcttgagtt
    42241 gggatttact gtggagattt ttgagaatct ggtcactttc acttagggcc atatccacaa
    42301 tctcagcagc ctgttcacgc gccttgttaa gctcggtttc cttttcacga ttaagctcgt
    42361 tgtagagttt ttttagcgca cggttcatct tgagattttc ttgctccacc tcacggatat
    42421 tgtccaagcg tttgcggctt tccagcgtct gctcttctaa ttgctcaatg atacgattga
    42481 cgtcattgtc ctgatcgatc tgctgactgg catctcctac gataacttca gataggccta
    42541 gacgtttggc aatttcaaag gcattacttc ggccaggaac accctgcata aagcgatagg
    42601 tcgggcgaag agttgcagta tcaaactcca tactggcatt ttgcacaaag gctgtctcaa
    42661 taccgtaggc cttgagttct ggatagtggg tcgtcgccat ggtcttgatt tgacgcaggc
    42721 gaaggtcctc cagaatagcc atggcaaggg ctgctccctc ttggggatca gtaccagccc
    42781 ccaactcatc caaaagtaag agtgaatgtt ggttgacctt gccaagaata tccacgatat
    42841 tggtcatatg gctagagaag gtagacaagc tctgctcaat agactgctca tctccaatat
    42901 cagcaaagat ttcttcaaaa ataccaacac gacttccctt gtctgctaaa atcggcaatc
    42961 ctgactgggc catgacctgt gtcaagccca gagttttgag catgatggtc ttcccacctg
    43021 tattgggacc tgtaatgaca atagctgtta aatcttgacc aaaatagaca tcatttgcga
    43081 cggcattttt gaccaaagga tggcagacat ggagcagttg aatctcttga ttttctgaca
    43141 gctgaggcac gactgcttgt ctttcttgga taaatcgaac cttggcacga atcaagtcca
    43201 gatgaccgat aatccaagcg tcattagcaa tctcagccgc atgagggcgg acacgctcag
    43261 aaatttcttg gagaatgcga agcatttcat agcgctcatc tgctcgcaga ctagcaattt
    43321 cttcgctcag tttgactacc tcacgtggtt cgatatagac ggtgtttcca ctagcagaaa
    43381 tatcatgaac gacacctgca atcttattgc ggtaggtgtt tttgactggt aaaacctgac
    43441 ggccatttct gctagcaaca attccttccg tcaacatctg cgctttttgc ttgagcaagt
    43501 cttgtaaaac atcgcgtacc tgactctcgc tatcatgtat ttttcgacgg attcgcgcca
    43561 attcttcact ggcaaaattt tcaatgaaac ccgcatcatt aaaggcctga agatttcctt
    43621 gtaattgcgg aaaatcatgt aatttctcaa accaaagggc taattcttcc aagctgacat
    43681 tttccagatt ggtgtaaaaa ttttgaagtt ctcggctggc aagaagcacg cgtttcaaga
    43741 gtaggaactc ctcgatattg agatccgctc ccatctccaa cctcttgcag actcctgcaa
    43801 tttccttagt tgagagaata gtaaaatgcg gttgctcgac gaaaagagcc tgcatttcct
    43861 tcatctcagc aaaagcctgt ttgattttat ctgctttggc agtcggagcc agttgtctca
    43921 attgctccaa gccctgctcg gtcaacaaat gaggctcaaa caaggccttg accttatcga
    43981 actctaatgt ttctaatatt ttcttattca tctttatttc cttgtctttg aatgtctagg
    44041 tgtggtagct ttttacattc tgatagattc gagtcaaatc tgtaaacaaa gggctaggaa
    44101 aactcctgcc ctttttatcc gattaaattt gtcacccaga tttgtttgag ccaactggtt
    44161 gttatcggta tgctctggat gatgtgtttt gcgacgatac tcttttcaag aggattttgt
    44221 ataactgcca tggggatggt cgccaagatt gtcaaggcca tttgcaagac aaataaggtc
    44281 accaacatgg acaagatacc tgctgaaact tggaacaact taccacccag ttttttgcta
    44341 ggaatcaagt gtaagagaag accaagcaaa cgaccaatgc tatagacaat cccaaataca
    44401 agcaagtagc cgatacctgc ataaaagacc ttatccagct gaaagagttg atccgatggg
    44461 aaaaagaaag tcccctgacc ttcctgcgaa tttgcataag ggagcaataa atggaattgc
    44521 tctccaagcc ccttataaaa ctggccagcc ataaaagccg atgccatggc tgaaatcagg
    44581 taataaacct gtaagagcag gcctctccga tagccgatat aaaatcccca aaccaagacc
    44641 aatagaagaa ggaatgaaat cataaggaat cctcaatctt gctctgttct tgcttacaag
    44701 tcacaagctt gtgacggagt tcttctagct cttgctcctt atcgtcaaat tcaatctcac
    44761 ggctgagctg agttgataaa cagttgactg ccaacaaaag agcgattgtt tcatcatctg
    44821 cgctaggcat ttgttcttta attgcttggt atttttctgt cgcaacctta gcgatttcct
    44881 ccataaaaag gttatcatgt tcgcttgtca aggttaacga ttttttcccg aatgtaaatt
    44941 tgaatcgatt tagatttgcc ataaaattca cctcacgata ttataccaaa attcgctaat
    45001 tttgtcagtt tttacaaatt ttactgcttt tgtggtacaa tagaaactat ggcaagtatc
    45061 acactcacac caagcgaaaa ggatattcag gcttttcttg aacactatca aaccagtctg
    45121 gctcccagta agaatcccta tatccgctac tttttgaaac tacctcaagc aacggtttct
    45181 atctatactt ctggaaaaat cttgcttcag ggtgaagggg ctgagaaata cgctagtttc
    45241 tttggctatc aacttgtaga ggaaaacagg gggcaaaatc ttcctttgat tgggacagat
    45301 gaggtaggga atggttccta ctttggtggg cttgcagttg tggcttcctt tgtcacacct
    45361 gaccagcatg ccttcttacg aaaacttggt gtgggagatt ctaagactct gaccgaccaa
    45421 aagattcgtc agattgctcc tattctcaag gaaaaaatcc agcaccaggc actccttctc
    45481 tcacccagca agtacaacga ggtcatcgga gaccgctaca atgctgtttc ggttaaggtt
    45541 gccctccata atcaggctat ctatctcctc cttcaaaaag gtgttcagcc tgagaaaatt
    45601 gtgattgatg cctttaccag tgctaaaaat tatgacaagt acttggcaca agaagccaat
    45661 tgtttcagca atcctatcag cttagaagaa aaggctgagg gcaaatactt ggctgtcgca
    45721 gtttcttctg tcattgcgcg tgatctcttt ctggaaaatc ttgaaaattt gggacgagaa
    45781 ctgggttatc agctcccaag tggagctgga acggcttctg acaaggtggc tagccagatt
    45841 ttgcaagcct atggtatgca gggactcagc ttctgcgcca aattgcactt taaaaacact
    45901 gaaaaagcga aaaaacgctt agaaaggtaa gttatgaatt catttaaaaa tttcttaaaa
    45961 gagtggggat tgttcctcct aattctgtca ttactagctt taagtcgtat ctttttttgg
    46021 agcaatgttc gcgtagaagg acattccatg gatccgaccc tagcggatgg cgaaattctc
    46081 ttcgttgtaa aacaccttcc tattgaccgt tttgatatcg tggttgccca tgaggaagat
    46141 ggcaataagg acatcgtcaa gcgcgtgatt ggaatgcctg gcgacaccat tcgttacgaa
    46201 aatgataaac tttacatcaa tgacaaagaa acggacgagc cttatctagc agactatatc
    46261 aaacgcttca aggatgacaa actccaaagc acttactcag gcaagggctt tgaaggaaat
    46321 aaaggaactt tctttagaag tatcgctcaa aaagcccaag ccttcacagt tgatgtcaac
    46381 tacaacacca actttagctt tactgttcca gaaggagaat accttctcct cggagatgac
    46441 cgcttggttt cgagcgacag ccgccacgta ggtaccttca aagcaaaaga tatcacaggg
    46501 gaagctaaat tccgcttctg gccaatcacc cgtatcggaa cattttaaga gacctaagag
    46561 gccgagaatc accaatctca gcctcttctt ctatcgtgag aagtgattgt ttattgacaa
    46621 atactcaatg aaaatcaaag aacaaactag gaagctagcc gtaggctgct taaaacagtg
    46681 ttttgaggtt gtggatagaa ctgacgaagt cagctcaaaa tactgttttg aggttgcaga
    46741 tggaagctga cgtggtttga agatattttc gaagagtata aaataaaaac aatcccaact
    46801 ctcacctatt catgcaaagg aattttatgg aagtttattt ttcaggaacc attgaacgga
    46861 ttatttttga aaatcccagc aatttttatc gcatcctcct cctagaaatc gacgatacgg
    46921 acgcagagga ttttgatgac tttgaaatca ttgtcacagg aaccatggct gatgtaattg
    46981 agggcgaaga ctatactttt tgggggcaaa ttgtccagca ctccaagtat ggagaacaac
    47041 tgcaaatcag tcgttatgat cgcgcaaaac caactagtaa gggcttggtc aagtactttt
    47101 caagtagcca tttcaagggg attggtctca agacagctca gaaaatcgtg gatacctatg
    47161 gcgaaaatac cattgacgaa attttgcaac acccagaaaa gttagaaggc atcgcaggac
    47221 tctctgccaa aaatcgcgag gctttcgtct ccactctccg tctcaactac ggaacggaga
    47281 tggttttggc caaactagcc aactacggca ttcccaacaa actagccttt cagattcaag
    47341 acttttacaa ggaagaaacc cttgatgtgg ttgaaaatta tccctaccag ctggttgagg
    47401 atatcaaggg tttgggcttt accattgctg accaactagc tgaggaacta ggcatcgaaa
    47461 gtcaggctcc tgaacgcttc cgcgccggtc tagttcacag tctttttcag gcctgtatgg
    47521 aaacagggga cacctatgtt gaagcacggg atttgctgga acaaaccctt actctccttg
    47581 agtcttcccg tcccgtagaa ctagacccca gccaagttgc ccaagagctc tcctacctga
    47641 tcgaagaaga caaggttcag cagattgata ccaagatctt tgacaacagc ctctttttcg
    47701 ctgaggaagg catccgcagt cacttggttc gtatccttga aaaaggaaaa cagaagagtc
    47761 atgatttaga aaccattcaa aaacatatca ctactatcga ggaagagctg ggaattgagt
    47821 atgataacat tcaaaaacag gctatctgtg atgctatcca gaataaggtc tttatcctga
    47881 caggtggacc tggtactggt aagacaactg ttatcaatgg gatcatcgct gtttacgccc
    47941 tgttagaggg acttgacctc aggaagaaaa gcaatctgcc cattcttctt gctgctccaa
    48001 ctggacgagc cgctcgccgc atgaatgaat tgacaggttt gcctagcgcg accatacacc
    48061 gccacttggg aatgacaggt gacgatgata ccagtcatct ggaagattac ctagatgctg
    48121 actttatcat cgtggatgaa ttctctatgg tggatacttg gctggccaat caactcttct
    48181 ccaatatctc ttctaacagt aagatcctca tcgtaggtga cagtgatcag ctaccttctg
    48241 tcagtcctgg acaggttcta gcggatctgc ttcatattcc tttgattcct cagactcgct
    48301 tggaaaaaat ttatcgacaa agcgaagaat caaccatcgt caccctagct agtcagattc
    48361 gacagggcat cttgccagct gatttcaccc aaaaaaaagc tgaccgttcc tactttgaaa
    48421 ttgctagtgg ccatattcct gccaccattg aaaaaatctt aggtgccgcc ctcagaaatg
    48481 gtattcctgc ccgtgatatc caagttctgg ctcctatgta ccgagggacg gcagggattg
    48541 atgctatcaa tcagctcatg caagacctgc tcaatccccc acaaaaagat caactcagtt
    48601 ttgaagctcc tcagtgccac tatcgtaagg gagacaaggt cattcatttg gttaacgatg
    48661 ctgaaatcaa tgtctttaat ggggatttag gagctatcac agacctgatt cctggtaaat
    48721 acaccgaatc gaaacaagac gagattgtca ttgattttga tggtaatgaa gtctcttacc
    48781 cccgtaacga atggtacaag attcgcttgg cctatgccat gagtattcat aagtctcagg
    48841 gaagtgagtt cccagttgtc atcctaccga ttactagtgc tagccgacgt atgctggagc
    48901 gaaatctcat ctacacagcc attacacgtg ccaaaagcaa actcatctta ctaggcgaat
    48961 tacaagcctt cgactatgct acccaacaca tcggaactgc ccgaaaaacc tatctgattg
    49021 aacgcttcag tgatctactg gagaatgttg aagaaaagca acaagctgtc tctgaaacag
    49081 tcacatcaag tgcctctgaa caatcctaca tcctaaccga agaaaactgg gacagcattc
    49141 cagccatgat tgggattaca gacacagacc tcaaagagat ttttggaaaa tagtacatca
    49201 gaaaacccac caattcaggt gggttttctg tttattaaga ttattttact gttgctgtgc
    49261 ttgtaatcaa ttcaacagct tttttgattg tgatatcatg tttcaacatg tcagctgaaa
    49321 gcaagctttg tacttgagca acttccatgt tgtagtctgc tgccaattgc tcaacttctt
    49381 tttggatttc ttcttctgaa gcatcaaatc cttcagcttt ggcaactgct tcgataacaa
    49441 ggttagtctt agtacgtgac tcagcttctg cttggtattg gttgtgaagg tcttcttgag
    49501 tagttccagt gatttggaag tacatgtcag ggttgatccc ttgacgttgc aagttcccaa
    49561 ggaattcatt tactgaacgg tgaacttctt catggatcat ttcttctgga agttctacga
    49621 tttcagcgtt ttctacagct gtatcaattg ctgcaccttc aactgcatct ttgtaagctt
    49681 cttctttagc agcagccaat tctttgcggt atttttcttt caagtcagca agtgtttcaa
    49741 cttcttcatc aatgtctttt gcaagttcat cgtcaagagc tggaacttct ttagctttta
    49801 cttcgtggat agttgtcacg aatttagctt ctttacctgc aaggtcttct gcttggtagt
    49861 cttctgggaa tgttacgata acatcaacgg tttcgccagc tgagtgacct accaattggt
    49921 cttcgaaacc agggatgaat tgacctgaac caagtccaag tgagaagttt tcaccttttc
    49981 caccgtcaaa ttcaacaccg tcgatagaac caacgaagtc gatcacaaca gtgtcgccgt
    50041 tttcagcagc agcttccttg ataaccaatt cagccaggtt gttgcgttcg cgttcgatac
    50101 gctcttcaac atcagcgtca gttacttctt tttctacatc aactgatact tcaaggtttt
    50161 tgtagtcacc caattttact tcaggttttg taacgacttc agcagcgata acccagtctt
    50221 gacctttttc cattgaagtt acgtcaattt ttggttgggc aaccacttca agaccagctt
    50281 cttttacagc tgcttcataa gcgtttggca aaagagcgtt cattgcatct tgataaagag
    50341 cttcttcacc aaatttttgg tcgaagatag ggcgtggaag gtgaccttta cggaaacctg
    50401 gaacattaag agatttcttc actgacttga agacacggtc caattctggt ttgatttggt
    50461 cttgagagat agtgaaagtc aagacaccac ggtttgtttc tttgttttca aatgatacag
    50521 acattctgtc atttctcctt aaaatttttt aaatacagtc tattataaca ttttctataa
    50581 ataaaatcta gactaatgca gccaattata gacaacaagc ctttttccta actaaaacac
    50641 tcataaagta tagacaattt tagactactt tggatatctt ttggttagtc attttccaaa
    50701 actaatttat ctaatttttc agttatatag tagattgaaa ctagaatagt acacctctac
    50761 ttctaaaaca tttttagaaa tcgatttgac tgtcccgatc gatttgtcct gttcttgttt
    50821 cattttacta tatagatcgc attcgaaaga attcgttcca aaattgcttg gttcgttctt
    50881 ctcttggacg actaaagaat tgatgggcat tatttttttc aacaattttc ccactgtcca
    50941 taaaaataac atgatgggct acatctctag caaaacctat ctcataaagc tgatcaaaaa
    51001 ctcaatctga ggagaaaatc caataaggct ttccataata aaggacatcc tatcaagatt
    51061 tttgaacacc cgataggctg cctttttccg attttgaaga ctttttgtcc agcttctttt
    51121 accttataaa taacaacaaa aatcaaagac aagctagaaa gattaccgca gataactcaa
    51181 acagtgtttt gaggttgcag ataagactga cggagtcagc tcaaagcact gctttgaggt
    51241 tgtagataga actgacgaag tcagtaacat atgcctaaga caaagcgatg ctaacctgat
    51301 ttgaagagat tttcgaaaaa gattaaatat actctacaat ttgctcaatc aattcttggt
    51361 cgtctaaacc tgtaacttgt ataacaacat ctttgactga ttgtttagcc aacaattcac
    51421 ctaatcgaat actttcttca tcatttacat cgcgatagtc aaaggcatag ccaactgttt
    51481 taagtaggtt tttatatgac aaactgagtt ctttcaattc acgtatcggc cggatgaatc
    51541 gttcattata gcctaatttt cggattggag tgcgagctac gcgactaacc tcgtccgcta
    51601 tgaaagggtt ttcaaaccgt tctataatga ctttgtgata attctccaat tcttttttat
    51661 caaagttcca tttggcaatc aagagactcc gaatttcagc taatacagat tcaatccgag
    51721 atttgatatt aggattttga agagcttcca aaattgtctt ggcaccataa tgcgcaccaa
    51781 tgtaagctga agttgcatgt ccagaattga ctgaaaaaag ttttcgctca ataaagggtt
    51841 ctaaatcttc ttcataatgc acatctttta gacgtaaatc tggattttta agacgcttgg
    51901 tttccacgac ccattcatta aagggctcga ccacaacaaa aagggaatct tcgtgacttt
    51961 gtgctggaac aatcctgtct actgcagcat ttggaaaacc tatgtagtta tcagcaaatg
    52021 tcaaaccttc cggacttaaa tatttcttga cttcttgata aagaaattga gacccgccaa
    52081 tcatattttc acaggccata acatccaatg cctgtgtatt tcctgcaact cggcgagctt
    52141 cgattccttt ggctagaagt tcggcgataa aagggagtat attaggtccg attgcagtag
    52201 taataatatc cgtcttttga atcgcttcaa tgacttgctc aggatgttct ttgctattaa
    52261 tgccagccac attagttact tctatacgag actgtccttt ctgtgcaatt tcaatttcat
    52321 acttgccctt ttcatttaga gcatgaatta tctgattatt gacatccaca aaatcaatat
    52381 ggaaaccatt tttaaataga atttcaccta taaaaccacg accgatatta ccggcaccaa
    52441 aatgaacaga atgtttcatt caatttctcc ttttcctatt tgagggacat atatactaga
    52501 tgacaaatga cgaaattcaa ttattcaaca gcatcaaata agcgcaatac ttcctctttt
    52561 gactgagcat ctgctagttt aagaacatta tctacatctg cacagaagat agaaattttc
    52621 tgaataattt ctaagtgttc attaccaata ccagcaatac caaaaagaac cgttgccact
    52681 tgagggttag atacattccc aaaatcaacc cctataggga cttgaacgac tgtaatacca
    52741 gacttgagga catccttttt tgctgcatct gttccatgcg gtatggcgat aaagttaccc
    52801 atgtaaacag atagctcttt atctcgctca atcatggctt caatatagtc ttcattaaca
    52861 tatccaccct cataaagaac ttgcccacaa taacaaatag cttcctcctt gttagaaaat
    52921 tgtttattaa gcttaatcaa atgtttttca agtttcatat tagttctcca atttcttaat
    52981 tttttcgtta aaaatagtat ttagcatctg ataaataatg gattgatttc ccgtcttgta
    53041 aatctctgta taaagatgat tttcaataat cgactgacta atagctgtca ttaaatctct
    53101 cgcttcctcg ctagcttctt tagacattag cattagcaga caccttttga cctcttcttc
    53161 ctctcgtttc attgacaatg cggagatagg tagtttgagt tcaaacatag taaaactatt
    53221 tgttgttact ttgctagact gactatgtaa aagcaccaga ccagtattag gaatagccat
    53281 aggactattc tggaagtgag ataacaattt tcttgttagg taatctctgt cactcacatt
    53341 cttctgatat tggatgattt gttctaccgt gtgctcaaat gattgattat tctccaattg
    53401 aaccaactcg aattgactca aaagctgact actagatatt aaataatctt gcaagtcata
    53461 acttttctct ggagcgatag catcacgcgc gacaattgca cgatgtgcct gtacatactg
    53521 aagtcgttcc tgtaattcaa gcaattcttt gacggttgga aaactagaaa ttacatcgat
    53581 ttcctgatta gtcagcggct tggtagataa aatataatca tactgactga gatcaatact
    53641 gtggtaatct actagagact gaatatctat caactctaca aaaggagcaa cactcttaat
    53701 tttactgact aataaatctc tagtgacccg acgttcatcc gttaaaagca aaacacggac
    53761 tggataaatc tctggactac ggcctaagct agagataaaa tgtagggcaa tcatgccata
    53821 ctcatactct gtatgaagat atttcggaaa aatatcattc actaaaagac tgatgactgt
    53881 ataaagaaat ttattccttt caactaaaat ctggacagat tctggcaaat tttcaccctg
    53941 aaaaaggata gggacgccta aactgagccg aatatgatgg aaaagaaaat tgaataaaac
    54001 cttgtcctta aaaaagtcaa tcttggtata catggaaacc gtatcaatca gatttgaaat
    54061 attgtagaaa aattcaccat caaatttctc cgtaaagagc ggattgtcct gacgtttaat
    54121 gattaattca tccaagatgc tcgcaaaata gataatttcc tgaatactat aaaattgtgc
    54181 agtctgctta gagtaagctt gaaaaatttt ttgagaaatt tccaaagcct gcttactagt
    54241 attaggtgaa ttttcaatgt tttgctcctg acctataaga gataacaaga tcgcaaaaaa
    54301 catcttcatc ctagcatcca tatctggaaa acctgacagt tgcttattaa caatctgact
    54361 ggccagccta gttctatctg cttctaaaat atcaaagctc ccaaaattac cggttgaaaa
    54421 atctgctact gagatacagt ttgtcagtaa aatagccaaa aatcttctct taccaactga
    54481 atcaccagaa atccgataac ctttttgtcg ttcaattttc agatcaaagt ctaaaagacg
    54541 cttatcaata tctgaaatat cctgaataat agttacatta ctgactttcg tgcactcttg
    54601 caatgcttca ttggtgacaa aaccactctc agtcagaagg cgataggtaa tcaactcttg
    54661 tctttcttgg ggactatact caactaacac ttcaagttct gtcggcaaat catccaactc
    54721 tccagtcaaa atatagtatt tcccatgctt cgttatttcg attccatatt gctccatgct
    54781 atctgtcaaa tctgataaag ttcgataaat tgttctagat gaaacctgta agatttcagt
    54841 catatcttgc attgaaagct tccctacatg taggaaagcc ttcaataatt gttcttctcg
    54901 tttggttaat agcattcgta atttagaaac ctctagttct atttgtacat tctagcagcc
    54961 attttgtcat attctggtgt tgttactaaa ctatccacaa taagaaattg agaattcggt
    55021 gctgcttgct gcacttctgc ctgtaaagaa atagttgtta caatcattat gtttttagaa
    55081 ttaaattcac ctaattctga aattttggca gtagaaactg gaatacgaat attcttgttt
    55141 ctaaagatag cccgaatcgt ttcacagccc atagttgcag ttccctgtgc tttaccataa
    55201 gcaactacta cagcatcaat atggttaagg tcaatttcct gactatctac tggtgctgaa
    55261 gttggtatat ctccttcaat ttctgctatt ggagaagctc ctgttaatga agctacaatt
    55321 tcatcataac gaggggaccc taagaaatta tcaacagaaa catgaatagc acttggactc
    55381 ttgtctttag ctcttggtgt cagttcttcc tgagtaacaa ttaatgtttt tggtgtatca
    55441 agcaaatttg agattgcctg attagatact ggaatctcta gacctgcttt tttaacctta
    55501 tctcgaagaa tactagctcc catagcagag cttcccatac cagcatcgca ggcgaaaatg
    55561 attttttcca ctgagtctgt cgaaacaact gcatcaacag aagttgatac taactgacct
    55621 ttagactgag ccttagctgc ttgggtagcc gcctgagcag cttcgagcga atcctcagtt
    55681 gacttgtctg catgaagaat aagggctgct acaaggaaag aaacaactgc tgccactaaa
    55741 acacctaaaa gaacatttag atggggccaa acaccttttg gcgccgtagc cataatcgca
    55801 ataatagaac ctggtgaagc tggagattta agaccagcgt ctaagagttg aaaagtaaaa
    55861 gttccagaga tacctcctgc catagcagct aaaaatagag taggcttcat cataacataa
    55921 ggaaagtaaa tttcatgaat ccctccgaag aaatgaataa ccattgcccc ccaagaagaa
    55981 gatttagcag aacctttacc gaatacagca taagctaata gaattcccag gcctggtcca
    56041 ggattagctt ccaataggaa gagaattgac ttaccagctt gagctacctg ttctactccc
    56101 agaggagtaa aaatgccatg attgagggca ttattgagga aaaggacttt agccggttcg
    56161 atgataatat tagccatagg aaggaggcga gcattgacaa tagcctcaac accattccca
    56221 acagctccag taagagtcga tacgactgga ccgattgcgt agaaagccaa aagcaataat
    56281 gcaaaaccaa cgagaccagc tgagaagtta ttaactaaca tttcaaatcc gggacgaatt
    56341 ttttcttgga acttctcatc aaatttcttg atagtccatc ctcccagtgg gcccattacc
    56401 atagctccga taaacatagg aacactagaa cctgtaattg caccaacagt agcaatagct
    56461 cctacaacgg caccacgttg gccatggatc atatatccac ctgtgtaacc aatcaggatt
    56521 ggcaataaat acgttaacat aggaccaaca acagtagcta actgttcatt tggcagatag
    56581 ccatcagcga taaagagggc agtcaatact ccccaagcaa taaatgctcc aatattgggc
    56641 ataaccatat ttgaaagcga tgtccctagt ttttgaaccc tgactttcaa tgatactttt
    56701 tcttccatta gatcatcctc cttttcttaa aactagtata tacaaagtta aaaaccttta
    56761 aaactaaagt tttgtcacag attttgtgtc aaaacattac ttttgacgag gctgggcaaa
    56821 aaggcttaaa aattataaaa cgcatcatat caggtgtaca tgaactgcac cccaaaagt
//
LOCUS       DBERXF010000009        50875 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.09, whole genome shotgun sequence.
ACCESSION   DBERXF010000009 DBERXF010000000
VERSION     DBERXF010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 50875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50875
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.09"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            148..1167
                     /gene="galE"
                     /locus_tag="ACL8JK_000616"
     CDS             148..1167
                     /gene="galE"
                     /locus_tag="ACL8JK_000616"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGS1785547.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            1169..2122
                     /locus_tag="ACL8JK_000617"
     CDS             1169..2122
                     /locus_tag="ACL8JK_000617"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1785548.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(2184..2390)
                     /locus_tag="ACL8JK_000618"
     CDS             complement(2184..2390)
                     /locus_tag="ACL8JK_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGS1785549.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            2442..2918
                     /locus_tag="ACL8JK_000619"
     CDS             2442..2918
                     /locus_tag="ACL8JK_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGS1785550.1"
                     /translation="MAKEPWQEDIYDQEESRAGHRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            2927..3598
                     /gene="cmk"
                     /locus_tag="ACL8JK_000620"
     CDS             2927..3598
                     /gene="cmk"
                     /locus_tag="ACL8JK_000620"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGS1785551.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            3729..4067
                     /locus_tag="ACL8JK_000621"
     CDS             3729..4067
                     /locus_tag="ACL8JK_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGS1785552.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            4070..4699
                     /locus_tag="ACL8JK_000622"
     CDS             4070..4699
                     /locus_tag="ACL8JK_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HGS1785553.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            4939..6090
                     /locus_tag="ACL8JK_000623"
     CDS             4939..6090
                     /locus_tag="ACL8JK_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS1785554.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            6403..7152
                     /gene="truA"
                     /locus_tag="ACL8JK_000624"
     CDS             6403..7152
                     /gene="truA"
                     /locus_tag="ACL8JK_000624"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGS1785555.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            7142..7915
                     /locus_tag="ACL8JK_000625"
     CDS             7142..7915
                     /locus_tag="ACL8JK_000625"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGS1785556.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            7893..8354
                     /locus_tag="ACL8JK_000626"
     CDS             7893..8354
                     /locus_tag="ACL8JK_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS1785557.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            complement(8613..8861)
                     /locus_tag="ACL8JK_000627"
     CDS             complement(8613..8861)
                     /locus_tag="ACL8JK_000627"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1785558.1"
                     /translation="MASTSLQAPAKICFILIKLYSPYAFLSKYLGAILLSFFCYYAKE
                     IGCNNLTLSVWNDNEGALRFYQRQGMKPQETTMEMIID"
     gene            complement(8809..9891)
                     /locus_tag="ACL8JK_000628"
     CDS             complement(8809..9891)
                     /locus_tag="ACL8JK_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGS1785559.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(10017..10799)
                     /gene="gatD"
                     /locus_tag="ACL8JK_000629"
     CDS             complement(10017..10799)
                     /gene="gatD"
                     /locus_tag="ACL8JK_000629"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HGS1785560.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(10799..12142)
                     /gene="murT"
                     /locus_tag="ACL8JK_000630"
     CDS             complement(10799..12142)
                     /gene="murT"
                     /locus_tag="ACL8JK_000630"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HGS1785561.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILEAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(12241..13557)
                     /locus_tag="ACL8JK_000631"
     CDS             complement(12241..13557)
                     /locus_tag="ACL8JK_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGS1785562.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGTFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            13751..14977
                     /locus_tag="ACL8JK_000632"
     CDS             13751..14977
                     /locus_tag="ACL8JK_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HGS1785563.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILAGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            15176..16750
                     /locus_tag="ACL8JK_000633"
     CDS             15176..16750
                     /locus_tag="ACL8JK_000633"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS1785564.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            17014..17802
                     /gene="codY"
                     /locus_tag="ACL8JK_000634"
     CDS             17014..17802
                     /gene="codY"
                     /locus_tag="ACL8JK_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGS1785565.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            17802..18377
                     /locus_tag="ACL8JK_000635"
     CDS             17802..18377
                     /locus_tag="ACL8JK_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGS1785566.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            18459..18544
                     /locus_tag="ACL8JK_000636"
     tRNA            18459..18544
                     /locus_tag="ACL8JK_000636"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18493..18495,aa:Leu,seq:aag)
     gene            18827..19957
                     /locus_tag="ACL8JK_000637"
     CDS             18827..19957
                     /locus_tag="ACL8JK_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785567.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(20104..20250)
                     /locus_tag="ACL8JK_000638"
     CDS             complement(20104..20250)
                     /locus_tag="ACL8JK_000638"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785568.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            20458..21216
                     /locus_tag="ACL8JK_000639"
     CDS             20458..21216
                     /locus_tag="ACL8JK_000639"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS1785569.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            21304..21816
                     /locus_tag="ACL8JK_000640"
     CDS             21304..21816
                     /locus_tag="ACL8JK_000640"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGS1785570.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            21998..22942
                     /gene="metA"
                     /locus_tag="ACL8JK_000641"
     CDS             21998..22942
                     /gene="metA"
                     /locus_tag="ACL8JK_000641"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HGS1785571.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            22951..23628
                     /locus_tag="ACL8JK_000642"
     CDS             22951..23628
                     /locus_tag="ACL8JK_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGS1785572.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTSQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            23726..24484
                     /gene="tpiA"
                     /locus_tag="ACL8JK_000643"
     CDS             23726..24484
                     /gene="tpiA"
                     /locus_tag="ACL8JK_000643"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGS1785573.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            24522..26027
                     /gene="lytC"
                     /locus_tag="ACL8JK_000644"
     CDS             24522..26027
                     /gene="lytC"
                     /locus_tag="ACL8JK_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HGS1785574.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDFN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            26524..27042
                     /locus_tag="ACL8JK_000645"
     CDS             26524..27042
                     /locus_tag="ACL8JK_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGS1785575.1"
                     /translation="MVELKKEAAKDVATLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLITLFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            27172..27678
                     /locus_tag="ACL8JK_000646"
     CDS             27172..27678
                     /locus_tag="ACL8JK_000646"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGS1785576.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            27678..27848
                     /locus_tag="ACL8JK_000647"
     CDS             27678..27848
                     /locus_tag="ACL8JK_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785577.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            27880..29112
                     /gene="clpX"
                     /locus_tag="ACL8JK_000648"
     CDS             27880..29112
                     /gene="clpX"
                     /locus_tag="ACL8JK_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGS1785578.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            29121..29708
                     /gene="yihA"
                     /locus_tag="ACL8JK_000649"
     CDS             29121..29708
                     /gene="yihA"
                     /locus_tag="ACL8JK_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGS1785579.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            29719..30099
                     /locus_tag="ACL8JK_000650"
     CDS             29719..30099
                     /locus_tag="ACL8JK_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGS1785580.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            30151..31041
                     /gene="rapZ"
                     /locus_tag="ACL8JK_000651"
     CDS             30151..31041
                     /gene="rapZ"
                     /locus_tag="ACL8JK_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGS1785581.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            31038..32015
                     /locus_tag="ACL8JK_000652"
     CDS             31038..32015
                     /locus_tag="ACL8JK_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HGS1785582.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDFRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            32012..32923
                     /gene="whiA"
                     /locus_tag="ACL8JK_000653"
     CDS             32012..32923
                     /gene="whiA"
                     /locus_tag="ACL8JK_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGS1785583.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(32957..33925)
                     /locus_tag="ACL8JK_000654"
     CDS             complement(32957..33925)
                     /locus_tag="ACL8JK_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS1785584.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIYPEQKVQPKHSTSL"
     gene            34061..34918
                     /gene="cdaA"
                     /locus_tag="ACL8JK_000655"
     CDS             34061..34918
                     /gene="cdaA"
                     /locus_tag="ACL8JK_000655"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGS1785585.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYMSTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            34905..35684
                     /locus_tag="ACL8JK_000656"
     CDS             34905..35684
                     /locus_tag="ACL8JK_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGS1785586.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            35708..37060
                     /gene="glmM"
                     /locus_tag="ACL8JK_000657"
     CDS             35708..37060
                     /gene="glmM"
                     /locus_tag="ACL8JK_000657"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGS1785587.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            37134..37508
                     /locus_tag="ACL8JK_000658"
     CDS             37134..37508
                     /locus_tag="ACL8JK_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGS1785588.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            37510..38358
                     /locus_tag="ACL8JK_000659"
     CDS             37510..38358
                     /locus_tag="ACL8JK_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS1785589.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            38624..39391
                     /gene="dapB"
                     /locus_tag="ACL8JK_000660"
     CDS             38624..39391
                     /gene="dapB"
                     /locus_tag="ACL8JK_000660"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGS1785590.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            39388..40587
                     /locus_tag="ACL8JK_000661"
     CDS             39388..40587
                     /locus_tag="ACL8JK_000661"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGS1785591.1"
                     /translation="MRLTQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIH
                     DVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSA
                     VSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDA
                     LRIMRGFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLA
                     SMIESQAYDYLPDMASSQNKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKS
                     WKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQARGKEVNPQAI
                     TEKYQSLTIHDKKDIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIH
                     AYLREKK"
     gene            40584..42455
                     /locus_tag="ACL8JK_000662"
     CDS             40584..42455
                     /locus_tag="ACL8JK_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS1785592.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYRGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIEALEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(42598..43782)
                     /gene="mntE"
                     /locus_tag="ACL8JK_000663"
     CDS             complement(42598..43782)
                     /gene="mntE"
                     /locus_tag="ACL8JK_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HGS1785593.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            44086..46782
                     /locus_tag="ACL8JK_000664"
     CDS             44086..46782
                     /locus_tag="ACL8JK_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGS1785594.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDITPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            46795..47586
                     /gene="yghU"
                     /locus_tag="ACL8JK_000665"
     CDS             46795..47586
                     /gene="yghU"
                     /locus_tag="ACL8JK_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HGS1785595.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            47702..48112
                     /locus_tag="ACL8JK_000666"
     CDS             47702..48112
                     /locus_tag="ACL8JK_000666"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGS1785596.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRV
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            48124..49719
                     /locus_tag="ACL8JK_000667"
     CDS             48124..49719
                     /locus_tag="ACL8JK_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785597.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVNDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            49886..50050
                     /locus_tag="ACL8JK_000668"
     CDS             49886..50050
                     /locus_tag="ACL8JK_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HGS1785598.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGIALV
                     LAAVWLGWPK"
     gene            50129..50857
                     /gene="yaaA"
                     /locus_tag="ACL8JK_000669"
     CDS             50129..50857
                     /gene="yaaA"
                     /locus_tag="ACL8JK_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HGS1785599.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
BASE COUNT        14812 a         9527 c        11605 g        14931 t
ORIGIN      
        1 aaggcgacgt tgacgtggtt tgaattggat tttcgaagag tataagcatt ttactgaaat
       61 tttatcaggt agtttaggat ggcaaatgac attccctgtc aaaaatggta aaataagaaa
      121 aaataatctg agaatcgagg aaaaaagatg caagaaaaga ttttggtaac tggtggtgcc
      181 ggttttattg gaacccacac tgttattgaa ttgatccaag caggccatca agttgttgtg
      241 gtggataatc ttgtcaatag caatcgtaag agtttagaag ttgttgaaag aatcacagga
      301 gttgagattc ctttctatga ggcagatatt cgtgacacag ctaccctcag agatattttc
      361 aagcaggaag aaccgactgg tgtcattcac tttgctggtt tgaaggctgt tggcgaatca
      421 acacgtatcc ctcttgccta ctatgacaac aatatcgctg gaactgtcag ccttttgaaa
      481 gccatggaag aaaacaactg taaaaacatc atcttcagtt cttctgcgac agtttacggg
      541 gatccgcaca cagtgcccat cttggaagat ttcccacttt cagtgaccaa cccatacggt
      601 cgtactaagc tcatgctaga ggaaattttg actgatattt acaaagcaga ctcagaatgg
      661 aatgttgtct tgcttcgtta ctttaaccca atcggagccc atgagagtgg tgatttggga
      721 gaaaatccaa acggtattcc aaacaatctc ttgccatatg tgactcaagt agccgttgga
      781 aaattagagc aagtgcaagt gtttggagac gattacgata cggaagatgg aacaggtgtt
      841 cgtgactata tccacgttgt cgatttggct aagggtcacg ttgcagcttt gaaaaaaatc
      901 caaaaaggtt caggactaaa cgtttataac cttggaactg gtaaaggtta ctcagttctt
      961 gaaattatcc aaaacatgga aaaagcggtg ggacgtccta ttccttaccg catcgtagaa
     1021 cgtcgcccag gtgatatcgc tgcctgctac tcagacccag caaaagctaa agcagaactc
     1081 ggttgggaag cagaactcga catcacccaa atgtgtgaag acgcatggcg ttggcaaagc
     1141 aagcatccaa atggatttga agactaagat gatgatttca atcatcgtcc cttgtttaaa
     1201 cgaagaggaa gtacttcctc ttttttatca ggctctggaa gctttacttc cagatttgga
     1261 aacagaaatc gagtatgtct ttgtcgatga tggatcaagt gatgggacct tggaactctt
     1321 aaaggcctat cgggagcaaa atccggcagt ccattatatt tctttctctc gaaattttgg
     1381 caaagaagca gccctttatg caggcttgca atatgcgaca ggagatttgg tggtggtgat
     1441 ggatgcagac ctccaagatc ctcctagtat gttgtttgag atgaaaaatg tactagacaa
     1501 aaatgtagac ttggactgcg ttgggacacg gagaactagt cgggagggag aacccttctt
     1561 tcgcagtttc tgtgctgttc tcttttatcg cctcatgcaa aaaatcagcc cagtagctct
     1621 gccgtcgggt gtccgtgatt ttcgtatgat gagaaggtct gtagtcgatg ccattttaag
     1681 cttgaccgag tccaatcgtt tttcaaaggg gctcttcgcc tgggtgggtt tcaaaaccta
     1741 ctatttggac tatccaaatg tcgaaaggca ggctggcaag accagttgga gttttaggca
     1801 actctttttt tactccattg aagggattgt taatttttca gatttccctt tgactatagc
     1861 ctttgtagct ggtctcctat cttgttttct ttctctgctg atgacctttt ttgttgtggt
     1921 tcggaccctc attttgggca atccgacatc tggttggacc tctctgatgg ctgttattct
     1981 ctttcttgga ggcattcaac tcttgaccat tgggattctc ggtaagtata tcagtaagat
     2041 ttatttagag actaaaaaaa gaccacttta tcttatcaaa gaaaaaagtg accttcctga
     2101 ttttacagaa aaaataaagt gaaaagacta taattttaca tggaaatgtg ctaaactaga
     2161 gggagtggat tatcgccatt gatttaggct tcctggtttc caatcagggc gcgagttggg
     2221 caatttttaa cagcctctaa gacatcctga ctaggagaaa tttctttttc cagttggtca
     2281 gggtcatcgt aaaaacgcac gattccatta tcgtggtaat caaataaatc agaataagtt
     2341 tggcaaagtc cacaggcgat acatcgttca ggtataagtg tgattttcat gttcatattt
     2401 atattgtaat aagaaaagta aaaaaaaaca aggagtaagg tatggcaaaa gaaccgtggc
     2461 aagaagatat ttatgatcaa gaagaatcaa gagcagggca tcggcatcga aaccacggag
     2521 gggctgatag gatggctaat cgtattttga cgatcctagc tagtattttc tttgtaattg
     2581 tggtggtgat ggtcatcgtt ctcatctatc tatcatcggg ggggagtaat cgcacagcag
     2641 ccttaaaaga ctttcatgat tctgatgcaa gtgtagtaca aatctcatct tcaagcagtt
     2701 ctcagcctga gcagagttca gagccagaat ctacttctag tagttcagaa gaagctgcta
     2761 atcctgaagg aacgattaaa gttctcgcag gagaagggga agcagctatt gccgctcgtg
     2821 caggaatctc cattgctcag ttagaggcct tgaatcctgg gcacatggct acaggatctt
     2881 ggtttgctaa tccaggtgat gttataaaaa taaaatagga gccgatatga aaacaattca
     2941 aattgctatt gatggtcctg cttccagcgg taagagtacg gtcgcaaaga ttattgctaa
     3001 ggattttggg ttcacctacc ttgatacagg agctatgtat cgtgcagcga cctatatggc
     3061 tcttaagaac caattaggag ttgaagaagt cgaagccctt ctagccttgt tggaccagca
     3121 tccaatcagc tttggacgtt cagaaactgg agaccagctt gtttttgtag gagatgtgga
     3181 tattacccat cctatccgtg aaaatgaagt gaccaatcat gtttctgcta ttgcagcaat
     3241 tcctgaagtg cgtgagaaac tggtttctct ccaacaagaa attgcccagc aaggcgggat
     3301 tgtcatggat ggtcgcgata ttggaactgt tgtattgcca caagcagaat tgaaaatttt
     3361 cctagtagct tctgttgatg agagagcaga gcgtcgttac aaggaaaata ttgccaaggg
     3421 aattgaaaca gaccttgaaa ccctaaaaaa ggaaattgct gcgcgtgact acaaggatag
     3481 tcatcgtgag acttctcctc tcaaacaagc agaggatgct gtctaccttg atacaactgg
     3541 tttgaacatt caagaagtag ttgaaaaaat caaagcagaa gctgaaaaaa gaatgtaaat
     3601 gtagaaaagc cgatagattg atatcggttt ttttctaaat ttgtcaaaat gctgatttta
     3661 gggtataata gttgctgttc gagaaatttt gattttcaaa gaatagtgaa tgatgataag
     3721 gagaaaccat gaacaattta ccaaattgtc caaaatgtaa ctcagagtat gtctacgaag
     3781 acggtgctct actggtttgc ccagagtgtg ctcatgagtg gaatcctgct gaagttgcag
     3841 aagtagaaga aggtcttgtc gctatcgatg ccaacggaaa taaattgact gatggtgata
     3901 cagtaactct catcaaggac ttgaaagtaa aaggtgcgcc aaaagatttg aaacaaggga
     3961 cgcgcgtgaa aaatatccgc atcgtagaag gcgatcacaa tatcgactgt aagattgatg
     4021 gttttggtgc catgaaactt aaatcagagt ttgtgaggaa gatttaagca tgtcaaaaca
     4081 ctataaactt gtattttata gccgtatctt cttgtttcta gcggctttta cgggagttta
     4141 tcttgaaatt actaggcatg gtggttttgg gatgcttctc tattacacgg ttctgtccaa
     4201 cctcttggta actattttta ccctttatct tctaaaggtt atgagccgtg taggtgaaaa
     4261 ttggcaaagg ccaagtctct tgcgcttaaa aggtggggtc accatgagta tcatgattac
     4321 ctgtgtgatt taccatttcc tcttggcgcc cattgcgact aatttctata ccctagaaaa
     4381 tttcctttgc cactatatcg ttcccatctg gtttttagcg gataccctct tttttgacaa
     4441 acagggtcaa tacaagattt gggatccagc agtgtggacc attttaccct ttctgtatat
     4501 gatgtttgct ctttttaatg gcttggttct aaaactcaat attccaaatg ccaaggataa
     4561 tcctttccct tacttctttt tgaatgtgaa caagggttgg aatgttgtgt ttaagtggtg
     4621 tctgattatc tttgttgcct atatggtagc aggatttatt ttctacttta tcaagcaaat
     4681 caagagaaag tcatcctaat actcttcgaa aatctcttca aaccacgtca gtttccatct
     4741 gcaacctcaa aacactgttt tgaacaacct gcggctagct tcctagtttg ctctttgatt
     4801 ttcattgagt ataagataca agggattcat tttcgaattt aagaaggagt ctacaaacca
     4861 atgaggcttc ttcttttctt gcttatttga taactatcaa aaaagtagaa gattaagaga
     4921 aatatagaaa gagatttcat gaaacaattt ttagaacggg ccagcatttt ggctctctcc
     4981 ctcgttttga ttacctcctt ttccatttcg agtgccctac cagccatgtt tgactattat
     5041 cagggttatt ctaaggaaca aattgagctc ttggtgagct tgccttcctt tggaatcatg
     5101 atgatgttac tgctaaatgg tttcttagaa aaaatatttc ctgagcgctt acagattagt
     5161 ttgggcttgc tgattttatc attgagcggt acagctccct tctggtacca agcctatccc
     5221 tttgtctttg gaacacggct tctctttggt ttgggtcttg ggatgatcaa tgccaaggcc
     5281 atttctatta tcagtgaacg ctaccaagga aaaaggcgaa ttcagatgtt agggctacgc
     5341 gcttctgcag aggtcgttgg agcttctctc attaccttgg ccgtcggtca gttgttggcc
     5401 tttggttgga cagctatctt tctagcctat agtgctggat ttttggtgct gcccctttat
     5461 ctgctctttg tcccttatgg aaaatcaaag aaagaagtca agaaaagagc gaaggaagca
     5521 agtcgtttaa ctcgagaaat gaaaggcttg atttttacct tagctatcga agcggcagtt
     5581 gtagtttgta ccaatacagc tattaccatc cgtattccaa gtttgatggt ggaaagagga
     5641 ttgggggatg cccagttatc tagttttgtt cttagtatca tgcagttgat cgggattgtg
     5701 gctggggtga gtttttcttt cttgatttct atctttaaag agaaactgct cctctggtct
     5761 ggtattacct ttggcttggg gcaaattgtg attgccttgt cttcatcctt gtgggtggta
     5821 gtagcaggaa gtgttctggc tggatttgcc tatagtgtag tcttgacgac ggtctttcaa
     5881 cttgtctctg aacgaattcc agctaaactc ctcaatcaag caacttcatt tgctgtatta
     5941 ggctgtagtt tcggagcctt tacgacccca tttgttctag gtgcaattgg cttactaact
     6001 cacaatggga tgttggtctt tagtatctta ggaggttggt tgattgtaat ctctatcttt
     6061 gtcatgtacc tacttcagaa gagagcttag gattgattcc taagtttttc ttttgatact
     6121 caatgaaaat caaagagcat agttgattga gtttggaata gtacgctgta gttgctaaaa
     6181 tatttctaga aattaatttg acttttctaa tagagttatt catatcttat ttcaatctac
     6241 tatagaaagc tagccgcagg ttgctcaaaa tagtgttttg aggttgcaga tggaaactga
     6301 cgtggtttga agagattttc gaagagtatg agatttttat acccatacaa tatttgtttt
     6361 aggtccttgt ttacagacta atttcttgat aaaatagagg ttatgacgag atataaagca
     6421 actatttcct atgatggtta tgcctttgct ggctttcagc gccagtctca tgcgcgtagc
     6481 gttcaggaag aaattgaaaa aaccttgacc agattaaata aagggcaaac cattactgtt
     6541 cacggtgctg gtaggacaga tagtggggtt catgccctgg gacaggtcat tcattttgac
     6601 ctgccttatc agatggatga ggagaaactc cgttttgcct tggataccca gtctcctgaa
     6661 gatattgatg tgatttcgat tgagcttgtg gcagatgatt ttcattgccg ttatgccaaa
     6721 catagcaaga cctatgagtt tattgtggat agaggacgtc ccaaaaatcc tatgcgccgt
     6781 cactatgcca cccactttcc ctacccactc gatgtggaac gaatgcagat tgcaatcaaa
     6841 aagctagagg gaacccatga ttttaccggt tttacagcct ctgggactag tgtagaggat
     6901 aaggttcgca ccatcacaga agctagttta atagtcgatg agacaggaca atttttgacc
     6961 tttacctttt caggaaatgg tttcttgtat aaacagattc gcaatatggt ggggactctt
     7021 ctcaaaatcg gtaacaaccg catgccagta gagcagattg atctcatctt ggagaagaag
     7081 gacaggcaac ttgcaggtcc cactgcagca ccaaatggtt tgtatttaaa ggagattcgt
     7141 tatgaagaat aatcgtattt tagcactttc tggaaatgat atttttagtg gtggtggact
     7201 gtcagctgat ttggctacct ataccttgaa cggcttgcat gggtttgtag cagtgacttg
     7261 tttgacagcc ttgacagaaa aaggatttga agtctttcca actgatgata ccatttttca
     7321 acatgaatta gatagcttgc gtgatgtgga atttggggga attaagattg gtcttctccc
     7381 tactgtcagt gtggctgaga aggccttgga ctttatcaaa caacgcccag gagtacctgt
     7441 ggtgttggat cctgtcttgg tctgcaagga aacgcatgat gtagctgtca gtgagctctg
     7501 ccaagagttg attcgctttt tcccttatgt cagtgtgatt acgcctaatc tcccagaagc
     7561 agaattatta tccggtcagg aaattaaaac cttggaagac atgaaaactg cagcgcagaa
     7621 attgcatgat ttaggagcgc cagcagtcat tatcaaggga ggcaatcgtc ttagtcagga
     7681 caaggctgtg gatgtctttt atgatggaca gacctttact atcctagaaa atccagttat
     7741 ccaaggccaa aatgctggtg caggttgtac ctttgcctct agcattgcca gtcacttgat
     7801 taaaggtgat aaacttttgc cagcagtaga aagctctaag gctttcgttt atcgtgctat
     7861 tgcacaagca gatcagtatg gagtaagaca atatgaagca aacaaaaaca actaaaatcg
     7921 cccttgtatc cctattaacc gccctttctg tggttctagg ttatttctta aaaatcccaa
     7981 cacctacagg aattctaact cttttagatg ctggtgtctt ctttgcggcc ttttactttg
     8041 gtagtcgtga aggagcggta gtcggaggac tagcaagttt cttgattgac ctcttatcag
     8101 gctaccctca gtggatgttc tttagcttgg tcaaccatgg cttgcaggga tttttcgcag
     8161 gatttaaagg aaaaagtcag tggttaggcc ttattttagc aactattgcc atggtaggag
     8221 gctacgcctt gggttctact ttgatgaatg gctgggcagc agccctccca gaaattctac
     8281 caaatttcat gcaaaatatg gtagggatga ttgtaggatt tattcttagt caaagtatca
     8341 agaagattaa gtaatactct tcgaaaatct cttcaaacca cgtcagtttc catctgcaac
     8401 ctcaaaacac tgttttgagc agcctgcggc tagctttcta gtctgatttt cattgagcat
     8461 aaagaggttg agtaaaaagt ctttcaaata agaaaaacgc atagtatcag gtgttgaatg
     8521 aacacctgat actatgcgtt ttattgtggg aagattttcc tcattttcta gtgaaattga
     8581 actttttcta acatcttttg atagatgact tcttaatcaa ttatcatttc cattgttgtt
     8641 tcttggggtt tcatcccttg tctttgataa aagcggagag caccctcgtt atcattccag
     8701 acacttaggg ttagattatt gcagccaatt tctttagcat aatagcagaa aaatgacaat
     8761 aaaatagccc ctagatattt tgaaaggaaa gcataggggc tatatagttt aatcaaaata
     8821 aagcaaatct ttgctggtgc ttgtaaagag gtcgaagcca tccttggtaa caacaccgca
     8881 gtcttcaata cgaacaccga ctttaccagg gatatagata cctggttcaa cagagaagca
     8941 catgccttct tcgatgacca tgtcgtttcc ttccatgata gatgggaatt catggacatc
     9001 cataccgata ccatgcccga gacggtggtt gaagtactca ccataaccag ctttttcgat
     9061 gacctcacgg gcagcgcggt ccacttcatg agcagtcaca cctggcttga taaagtcaag
     9121 agcagcttgt tgggcttcaa gagtcaagtt gtaaatatct ttcttgaatt ggtctggttt
     9181 gccgacagcg actgtacgag tcatatctga cgcatagcca ttgaccagaa cacccaggtc
     9241 aaagaggaga agagcatcat tttcaacctt attagctgct ggaatgccgt gtggattcgc
     9301 agcattatca ccagtcaaga ccatggtatc aaagctcatt tcgtaacctt cacgtttcat
     9361 ggcaaagtca atttgtgcga tgatatctgt ctcagtctta tcaagagaaa tattgtcaaa
     9421 accaacatga acagccttgt cagcataaag acctgcaacc atcatttttt gcacttcatc
     9481 agctgatttg atgaggcgca tgcgttggat acgaggagtg aggttgtcaa actcagcagt
     9541 ctcaaaaact gttttcaaac catggtattt ggtcaagatg agattgtcaa actcaacagc
     9601 gacacgtttg aagtcaagtt gtggaagagc atgtttgatt ttttgccatg gattttcaga
     9661 atcgacatag cccactactg ggaaggaaac ggtgctactt gcacgttcta cttcaagagc
     9721 tgggacaaag aggagaggtt cctgatctgc taggacaaag aggaacattt ggcgttcatg
     9781 gggatcactg taaaaaccag tgaggtaatt gattgtgacg gggtcagata cgacagcgac
     9841 gtctagtttt tctgattcaa gatatgttag gatttgttgt aatttagaca tatgctacct
     9901 tctttctatc cctctatttt ggcaaaaaat gagagaaaat gcaagggaga agggtaaaag
     9961 aaaagacaaa aaactccgac aagataacgg agttctttga tatcattttc ctttgtttaa
    10021 gaaaagtcag ccttgctttt gacgtcactg tactcttcag cgatttcttg gctgaggata
    10081 tcctcatagg cagggagttg gatatcctga ccatatttct tcttgagggc agtagtaact
    10141 aggcgataag ccagattggc attacgagag aggataggcc cgtggaagta ggaaccaaag
    10201 acattcttat aatgaacccc ttcaccgacc ttttcttcgt tgtttccatt tccatagaca
    10261 acctgtccca gcggtttttg gtcatcagag aggaaggtac ggccttggtg attttcaaat
    10321 ccatagtagg tttcatcgaa atcttcattg tgaatcttga tgtcaccgat aaaacggtta
    10381 ttggtctggt tgagcgtgta gtgtcccatg acccctagcc cttcgatacg ttttcctgaa
    10441 gcttcaacat aatattgacc caatagttgg aaaccaccgc agatagccag aactacaccg
    10501 tcgttttgga tgtagttgtc aatgctctct tttttagcag gtaggtcgtc tgcaatgata
    10561 ctttgttcaa agtcttgacc accaccgaaa aaggcgatgt cgtagtgatt ttcatcaaag
    10621 tcatcatgga gagaaacgat gtcaacggtc acatgggctc ccagtttttc agccacatac
    10681 ttgagcatga ggatgtttcc attgtccccg taggtattca tgagatttcc gtagaggtgg
    10741 gcaatgttga gctgataggg gtaattgcca tcttttgagg aaagtgaagt ataaaccatt
    10801 agttcatctc ctttctaaca atctgacgac tagccagcag ttcacgaaat tccagcatgg
    10861 cagtataagt tgccagaata taggcatgct tgcagtcttg attctcaatg gtcttgagaa
    10921 cttgctccag attactcgtt tcagtgattt tctcagctgg atagccagtc actcggaggc
    10981 gacgagcgat ttcagaatga cgaacaccgc cagcgttgat ttcaggaatg tccatgtcag
    11041 tgatttgttc aaagtctgca tcccagatcc agctagtgtc aattccatct gcatagttgg
    11101 cattaaggag gacagatagg ctaaatggat aaggtgctag tttgatcatt tcgatagctt
    11161 gggttgcacc gactggattt ttaatcaaga caagggtaca ttccttgtca ccgatatgaa
    11221 aggtttcttg gcgtccaaag acagcacggc tcttgtcaaa tccctgtttg atgagttgcg
    11281 aatcggcacc taggaaacgg gcgatggcca cagcagctag ggcgttatag atattataga
    11341 gcccgccgat ttggataccg tattcttggc cgtctatgac aaagcgagag cgattgttgg
    11401 tcaactcaac cagttttgtc aaacgatagt cgagatcagg acgtttgcat ccacaacctt
    11461 cacagatata ggcacccaag tttgcatagg tattatgctc atatttgagg atgccttggc
    11521 agtcaggaca gagaatccct tcggtattgt agtgagccag ttgggctggt cctttttcca
    11581 agtcaaaacc aaaatactct atagggtttg gaatagttgg cttgtagaaa agtggactgt
    11641 ctccgttaag gagaacagta gcagttggaa ctttccgaat ggcttccaat atcatgttat
    11701 aggtagtata gatttcaccg aaacggtcca tctggtcacg gaagatatta gtaatgacaa
    11761 aaagactagg ctggatatag tcacagatac gagatagact ggcttcgtca atttcgagga
    11821 cggcaatatt tttcccagtt tttgaagatt tggctgttag gaaggttgtt gcaatccctg
    11881 taatcatgtt ggcaccgctt gggttggtta gaacttgacc ataaacctct tttaaaatgc
    11941 cgacagtgag ggcagttgtc agggtttttc catttgttcc agtgacaacg acaatctcgt
    12001 agttcttagc taggttttgt aaaatatctt tatcaaattg aagggcgact ttacctggga
    12061 gcgtacttcc acgtccaaga cggcttaaaa cgaagtggga agaacgccca gcaagaaggc
    12121 ccaaagtagt ttttaagttc atgtttctat tatatcacaa aagagggaaa agacagattt
    12181 ggtgtttcgt agaagtaaaa acagcccaaa gagggctgtc agttaagatg agatttcaac
    12241 ttaaatcgca aacaagtcat tcaagttctc agccaaggtt gggtgagtga agatttgttt
    12301 tgtgaagtaa gtgtaaggaa tcttgttgtc catagcaaca gtaatgatgt tgatgatttc
    12361 ttgagaacct tctgagaaga tgcttgcacc aagaatttct tttgtttcag tattaacaac
    12421 agctttgaaa gttccgcgaa ggtctccatt tacgtgacca cgaggcatgg ctgcaacagg
    12481 gatttctttc actgcgtatg gaagtttcaa atcagctgct tggctttcag tcaaaccaac
    12541 ttgtgaaagt gcaggtgtga tgaacatagt atttggcaca ttgagacggt cctcaagtgt
    12601 gtagctgcca tctccagcaa ggtagctgta aacaacacgg aagtcatcaa gtgaaatgta
    12661 agtaaattga agaccaccgt tgacatctcc aactgcaaag acaccaggaa cgtttgtttg
    12721 acagtgttta tctactttaa tagcgccacg ttcagttagt tcaatatctg tattttcaag
    12781 ttgaagtggt tctacatttg gtttgcgtcc agttgcgtag agaagggcgt cgaaacggta
    12841 agtttcgtct tcagttacga caagcacttg gtcaccgtcg tttttaattt cagtagtatg
    12901 gatattttga agcaattcaa taccgtcttc ttccaggtat tgtttagcaa gagctgcgat
    12961 ggaaggttct gcacgaggta ggaatgtatc caaggcatct aggactgtaa ccttgcttcc
    13021 tagtttattg taaaggccag caaattcaag accgatattt ccgccaccaa ggactccaag
    13081 tttttcaggc aatttatcca agctttggat acctgttgag tcaaagacgt ttttgcttgt
    13141 agcaagtcca gggattggca agacgtttga aacagcacca gtgttgatga cgatagtttc
    13201 agcagtcaat tcttgttttt catcaccagc ttggatttcg atgactttat ttgaaaggaa
    13261 gtgagcttca gcatcaaaga tatcgacgcc agtaccagca acagtcgtat agtttttacc
    13321 gttgaggcga ccagtgatcg tgtttttggt agcaatgact tcttcaaaag acaagtcttt
    13381 ctcagcagca accagcaaag ttttagttgg gatacaaccg atgttgatac aagttccacc
    13441 gtacatagct ttgctacgtt caacgagggc aacttttttg ccagctgaag ccaatttacc
    13501 agctagtgtt ttaccagctt taccaaatcc gataacgatt aaatcataag ttaacattta
    13561 gaattcctcc tattcgaatt acattctagc acaagaaaaa aacttttgca caattctgct
    13621 acgaaaaaga cagaaaaata tgaaaacgct ttccaggcaa aaaactagta attttttgac
    13681 aagcttgata aactaaaatc ctatctattt ttatataaga tagaataaat gttcgaaaat
    13741 aggaggtttt atgaaatcga atcgttatat tattgccttt gctggggtca ttttacactt
    13801 aatgctgggt tcgacttatg cctggagtgt ttatcgtaac cctatcattg aaaaaacggg
    13861 atgggatcag gcttctgttg ccttcgcctt tagtctagca atcttttgtt tgggcttatc
    13921 ggctgcattt atggggcgtt tggtagaaaa atttggtccg aaagtcatgg gaagtctatc
    13981 tgcttttcta tacgcaggtg gaaatatctt agcaggattt gcaatagacc gtcaggagct
    14041 gtggttgttg tatctcgctt atggcatttt aggtgggctt ggtttgggag caggctatat
    14101 tacccctgtg tcgacgatta taaaatggtt tcctgataaa cgtggtctcg caacaggttt
    14161 agcgattatg gggtttggtt ttgcttcttt attgactagt cccatagcgc aacacctcat
    14221 cgcaggggta gggcttgtag aaacttttta tattttagga gcaagttact ttattatcat
    14281 gctcctagct tcacaattca ttaagcgtcc aaatgagcaa gagcttgcaa ttttatcttc
    14341 ttcagggaaa gaaaaaacag cctctttgac gcaaggaatg gctgcaaatc aggctctgaa
    14401 aagcaatcgg ttttatatgc tttggattat tttctttatc aacatagctt gtggtttagg
    14461 cttaatttca gcggcatcgc caatggcaca ggagatggct ggcttgtcta caagtcatgc
    14521 agcagtaatg gtgggtgttt tggggatttt caatggattt ggtcgcttgc tctgggcgag
    14581 tttgtctgac tatatcggtc gccctctaac ctttagtata ttactgcttg tcaatctttt
    14641 cttttctctc tcactttggc tctttacaga ttccgtttta tttgtagttg ctatgtctat
    14701 tttgatgact tgctatggag ctggtttttc tttgattcca gcttatctca gtgatatttt
    14761 tggaaccaag gaattggccg ctctgcatgg ttatatttta acagcttggg caatggctgg
    14821 tttagcggga cctattttat tagcagagac ttataaaatg gctcattcgt acacacaaac
    14881 cttgttcgtt tttctcattt tatacagtat cgccttggct ttgtcttatt atctaggtcg
    14941 ttcaatcaaa aaagaaagtc aaaaaccgct tacatgattt tctgtagaaa tggggctatc
    15001 ttttgctctg gtcttgtgtt atactagata ggttgcaaag aaaacagtac ttttcttttg
    15061 tggaaaagaa gcaacacgat tttatatcta gttatatgaa aatacgtcat aaaaagaaaa
    15121 gtataaacta agccctatag ggtggcttcg caccaccttt agaaagaaga ataacgtgaa
    15181 atttaatgaa ttaaacttgt ctgctgattt gctagcagaa attgaaaaag ctggttttgt
    15241 agaagctagt cctatccaag aacaaactat tcctttggcc cttgaaggca aggatgttat
    15301 cggtcaagct cagactggta caggaaaaac tgcagccttt ggcttgccta cccttgaaaa
    15361 aatccgtaca gaagaagcga ctatccaagc cttggtcatc gctccaactc gtgaactagc
    15421 tgtccaaagt caagaagaac tcttccgctt tggtcgtagt aagggagtca aagtccgttc
    15481 agtatatggc ggatcaagca ttgaaaaaca aattaaggct cttaaatctg gtgcccatat
    15541 cgtggtggga actccaggtc gcctcttgga cttgattaaa cgcaaggcct tgaaattaca
    15601 agacattgaa acccttatcc ttgacgaagc ggatgaaatg cttaacatgg gcttccttga
    15661 agacatcgaa gccattattt cccgtgtacc tgagaaccgt caaactttgc ttttctcagc
    15721 aactatgcca gatgccatca aacgtatcgg tgttcagttt atgaaagccc ctgaacatgt
    15781 caagattgcg gctaaggaat tgacaacaga attggttgac cagtactata tccgtgttaa
    15841 ggaacaagaa aaatttgaca ccatgactcg tctcatggat gtggcacaac cagaactcgc
    15901 tattgtattt ggtcgtacca aacgccgtgt ggatgaattg actcgtggtt tgaaaattcg
    15961 tggcttccgt gcagaaggaa ttcatggcga cctagaccaa aacaaacgtc ttcgtgtcct
    16021 tcgtgacttt aaaaatggca atcttgatgt tttggttgcg acagacgttg cagcgcgtgg
    16081 tttggatatt tcaggtgtga cccatgtcta caactacgat attccacaag atcctgagag
    16141 ttatgttcac cgtatcggtc gtacaggtcg tgctggtaag tcgggtcaat ctattacttt
    16201 tgttgctcca aacgaaatgg gttaccttca aatcattgaa aacttgacta agaaacgcat
    16261 gaaaggtctc aaacctgcaa gtgtagaaga atccttccaa tcaaaaaaac aggtagctct
    16321 caagaaaatc gaacgtgatt ttgcagatga aaccattcgt gccaactttg agaaatttgg
    16381 taaggatgct cgcaaattgg ctgctgagtt tactccagaa gaattggcaa tgtatatctt
    16441 gagtctgaca gtccaagacc cagatagcct tccagaagtg gagattgcac gtgaaaaacc
    16501 actaccgttt aaaccatcag gtaatggttt cggtggtaaa gctaagggag gtcgtggagg
    16561 ccgtcgtggg gacgaccgtc gagagcgtga tcgccgtggc aatggtcgcc gtgatgagtt
    16621 caaaaaagga agtcgtggca acgatcgttt tgataaggaa aaacgttacc gtaaggataa
    16681 taaaaaacca cgcaatactt taagcgaaaa gcaaacaggc tttgttattc gtaacaaagg
    16741 cgataaataa gaaaaagcgg ttcaaaatga atcgcttttt tatataagga gaccgaatgt
    16801 gaaaagacaa ataaaattat tatattatct tttgtaatgt tatgatacac aaaaataggc
    16861 aacttgtcaa tagaaaagga acaatttaat taaaaatatt ctggttttta attaaattgt
    16921 aagtcaatgc aagtcaataa ggaattttca gataattatt gaaaaagaga cgtttttatg
    16981 ttataatgat agcgattaaa ttcgaggtga aaaatggcac atttattaga aaaaactaga
    17041 aaaattacat caattttgaa acgctcagag gagcagttgc aggatgagct cccttacaac
    17101 gctattacgc gtcagttagc ggatattatt cattgcaatg cctgcattat caatagtaag
    17161 ggacgtctgc ttggctattt tatgcgttat aaaacaaata cagatcgcgt agagcaattc
    17221 ttccaaacta agattttccc agatgactac gttcaagggg ctaatatgat ttacgaaaca
    17281 gaagcaaact tgcctgttga gcatgatatg agtattttcc ctgttgagag tagagatgat
    17341 tttccagatg gcttgacgac tattgcaccg attcatgtat cggggattcg ccttggttct
    17401 ttgattattt ggcgtaatga taaaaaattc gaagatgagg acttggttct tgttgagatt
    17461 gccagtaccg ttgttgggat tcagcttctt aacttccaac gtgaagaaga tgagaaaaat
    17521 attcgtcgtc gtactgctgt caccatggcg gtcaataccc tttcttactc cgaactccgt
    17581 gctgtttcag caattttagg ggaattaaat ggaaatgaag ggaagttgac tgcgtcagtg
    17641 attgcagatc gtatcggaat cactcgctct gtgattgtca atgctcttcg taaacttgag
    17701 tctgcgggga ttattgaaag tcgctcactt ggaatgaagg gaacctatct taaggtcttg
    17761 atttcagata tttttgaaga agtgaagaaa agagattact aatgacaaag gctttaattt
    17821 cgattgatta tacagaagat tttgttgctg atagtgggaa gctgacagca ggtgctccag
    17881 ctcaggcgat ttcggatgcc attagcaagg taactagatt agcttttgaa cgaggagatt
    17941 atatcttctt tactattgat gctcatgaag aaaacgattg tttccatccg gaaagtaagt
    18001 tatttcctcc tcataatctg attgggacga gtggacggaa tttatatgga gatttgggga
    18061 tcttttatca agagcatggt tcagacagtc gtgtcttttg gatggataaa cgccattact
    18121 cagctttttc agggactgac ctagatattc gtttgagaga gcgtagagtg tctaccgtta
    18181 tcttaacagg tgtcttgacg gatatctgtg tcctacatac agctatagat gcctataatc
    18241 taggatatga catcgagatt gttaaaccag ctgttgcttc catctggcct gaaaatcatc
    18301 aatttgccct aggtcatttc aaaaatacac tcggagctaa gttagtagat gaaaatctaa
    18361 atgaactttc tgagtaacct ggttggtgaa aatgaaaaaa tttgaaaaaa agtgttgaca
    18421 agcatcccaa aagttgatat actagtaaag taatcgacgc ggggatggcg gaattggcag
    18481 acgcgcagga ctaaggatcc tgtgaccgct ttaggtcgtg agggttcaag tccctctctc
    18541 cgcataggaa aagagttagc taaagctagc tcttttgtat ttctctaaaa aattagaatc
    18601 cagtcaaatg tagtggagaa tcagcgaaaa tatgggaaaa ctgatccttg tttctgcttt
    18661 tgtcatagaa gaataataaa gattatcttc ttcaaattct ccgatattct ctaaagtttt
    18721 gtgcaagttg cacagaactt ttttattttt ttggtcatct tgccatagaa atataaagcg
    18781 ttttcatcta taatataatt atcaaaagac aaaaggagtt cacctcatgg tagaattgaa
    18841 tcttaaaaat atttacaaaa aatatccaaa cagcgaacac tattcagttg aagatttcaa
    18901 cttgaacatc aaagataaag aatttatcgt tttcgtagga ccttcaggat gtggtaaatc
    18961 aactacactc cgtatgattg ctggtcttga agacattaca gaaggtactg catctatcga
    19021 tggcgtggtt gtcaacgacg tagctccaaa agaccgtgat atcgccatgg tattccaaaa
    19081 ctacgctctt tacccacaca tgactgttta tgacaacatg gctttcggtt tgaaattgcg
    19141 taaatacagc aaagaagaca ttaacaaacg tgttcaagaa gcagctgaaa tacttggatt
    19201 gaaagaattc ttggaacgta aaccagctga cctttcaggt ggtcaacgtc aacgtgttgc
    19261 catggggcgt gcgattgtcc gtgatgcgaa agtattcttg atggacgaac ctttgtcaaa
    19321 cttggatgcc aaacttcgtg tatcaatgcg tgctgaaatc gctaaaattc accgtcgtat
    19381 cggagctaca actatctatg taactcacga ccaaacagaa gcgatgacac ttgcagaccg
    19441 tatcgttatt atgtcagcta ctaagaaccc tgctggtaca ggtactatcg gacgtgtaga
    19501 acaaatcggt actcctcaag aagtttacaa aaatccagtt aacaaattcg ttgcaggatt
    19561 catcggaagc ccagctatga acttcatcaa cgtgaaattg gttggtagcg aaattgtttc
    19621 tgacggtttc cgtttgaaag tgccagaagg agcattgaaa gttcttcgtg aaaaaggcta
    19681 cgaaggaaaa gaattgatct ttggtatccg tccagaagac gtgaatgcag aacctgcttt
    19741 ccttgaaaca ttcccagact gtgttgtaaa agcgactatc tctgtatcag aactgcttgg
    19801 ttcagaatct cacctttact gccaagttgg taaagacgag tttgttgcaa aagttgatgc
    19861 tcgtgactac ttgcaaacag gtgcaacagt tgagcttgga tttgacttga acaaagcaca
    19921 cttcttcgat gtagaaactg aaaaaacaat ctactaaaat aaataaaatt caaagcacta
    19981 caagaaaaga tatctcttta tcaattgtag tggagagata tcagttaatc tagggagaga
    20041 aacaaaatgc ttctctcctt tttgctaggg aagtcatatt atgcatctat attgtgatgc
    20101 tctttaatac tcttcgaaaa tctcttcaaa ccacgtcaac gtcgccttgc cgtacgtatg
    20161 attactgatt tcgtcagttt tatctgcaac ctcaaagatg tactttgagc agcttacggc
    20221 tagtttccta gtttgctctt tgatttccat tgagtattat ttgtgggtac catctacaag
    20281 tgaagctata tgcgtaaact acgtgagcaa ttgaattcga actagagagg taataataaa
    20341 tttatgctat agttatggtg acttgtatgc ttttgattct agtttatcaa ataatagatt
    20401 agaattgtca gataatatca ttttgtgtta taatgaagaa aaaacagagg tgttcaaatg
    20461 tcagaagcag gtcataagtt tttagcaaaa ttggggaaaa aacgcttacg tccaggtgga
    20521 aagcgtgcca cagattggtt aattgcagaa ggaggatttt caaaagaaaa gagaatacta
    20581 gaggttgcgt gtaatagggg aactacagca attgagttgg cacagcgttt tggttgcaag
    20641 ataactgctg ttgatatgga tgctcaagct ttagaagtgg ctaaaaaatc tgctggaacg
    20701 gcaggtgttg ctcatttaat cagttttgaa agagcaaatg caatgaaact tccttatcaa
    20761 gatgctagtt ttgatattgt tataaatgaa gctatgctga ctatgcaagc cgatcaagct
    20821 aagaaaaaat gtgtaatgga atatctaagg gtattaaaac ctggaggtct tctcttgaca
    20881 catgatgtgc ttcttaagga agctaaagag tctatcagac aggaattatc acaagcaatt
    20941 catgtaaatg taggtccttt aactcaagat ggttgggaac aggtgatgat agaatcaggt
    21001 tattgtgatg tgaaagcatt gactggtgaa atgacattaa tgaaattatc gggtatgatt
    21061 tatgacgaag gtttgctagg aactttgaaa atttgtgtaa atgcttgtaa aaaggagaat
    21121 agaaagcagt ttttaactat gtataaaatg tttgctaaga ataaacagaa attgggcttt
    21181 attgcgatgg ctagttataa atcgtcaaaa cgttagataa ttattgaagt taacttttcc
    21241 ttttttcttt cttaaaaaat atgctataat agagagtaaa aaactttgaa agaaagaaaa
    21301 aagatgaatt taaaagatta cattgcaaca attgaaaatt atccaaagga aggcattacc
    21361 ttccgtgata ttagtccttt gatggctgat ggaaatgctt atagctacgc tgttcgtgaa
    21421 atcgttcagt atgctactga caagaaagtc gacatgatcg tgggacctga agctcgtgga
    21481 tttatcgtgg gttgtccagt tgcctttgag ttgggaattg gttttgcgcc tgttcgtaag
    21541 ccaggtaaat tgccacgtga agttatttct gctgactatg aaaaagagta cggtgtcgat
    21601 accttgacta tgcacgcgga tgccattaag ccaggtcaac gtgttcttat tgtagatgac
    21661 cttttggcga caggtggaac tgttaaggca actatcgaga tgattgaaaa acttggtggt
    21721 gttatggcag gttgtgcctt ccttgttgaa ttggatgaat tgaacggccg tgaaaaaatt
    21781 ggtgactacg actacaaagt tcttatgcat tattaatgaa aacagtccct agggctgttt
    21841 tctctacact atgatataaa aatagactat aactagttag agaaaaacta taattgaaaa
    21901 ctatatcttc ttgcagtata ataaaaggac taagtgtttg agatttgtct tcaaacatat
    21961 gcaattattc ctgaaagagt acagttagga gagggttatg ccgattcgaa ttgataaaaa
    22021 attgccagct gttgagattt tacggacaga gaatatcttt gtcatggatg atcaacgtgc
    22081 tgcccaccaa gatatccgtc ctttgaagat tttaatttta aatctcatgc cacagaaaat
    22141 ggtcacagag acccagttgt tgcgccactt ggctaataca cccctacaac tggatattga
    22201 ttttctctat atggagagcc accgttctaa aacaactcgt tcagagcaca tggagacctt
    22261 ctataaaact tttcctgaag tcaaggatga gtattttgat gggatgatca tcacgggtgc
    22321 tccagttgag catttaccat ttgaggaagt ggactattgg gaggaattta gacagatgct
    22381 tgagtggtct aagactcatg tctattcgac ccttcatatc tgttgggggg ctcaggctgg
    22441 gctttatctg cgctatggtg tagaaaaata ccagatggac agtaagctat caggtattta
    22501 tcctcaggac accctaaaag agggtcacct tctatttaga ggctttgatg atagctatgt
    22561 atcccctcat tcacggcaca cggagatttc taaggaagag gtcttaaaca agaccaatct
    22621 cgagatttta tcagaaggac ctcaggttgg ggtttctatt ttggccagtc gtgatttacg
    22681 agaaatttat agttttggtc atttggagta tgaccgtgat accttggcaa aagagtattt
    22741 tcgagatcgt gatgcaggtt tcgacccaca tattccagaa aattacttta aagatgatga
    22801 tgttaatcag gtaccttgtc tttgttggtc ttcatctgca gccctctttt tcagtaattg
    22861 ggtaaaccat gcggtctatc aggagacgcc ttttgattgg agaaagatag aagatgatgc
    22921 atctgcatat gggtatttat aagaggaatt atgacatatt tagacgcttt taaatcaggt
    22981 accttggttt taccgagtgc cctgctcttg cattttaagg aactctttcc ttctagcgac
    23041 gattttctgg tttggcaatt tttctatttg caaaatacga caggcttaga agaaatgtcg
    23101 ccaagccaga ttgctgaaag gattggcaag gaaatttcgg atgtcaacca gtccatttct
    23161 aatctgacgg aaaggggact gctccagtat cgtactatcg aattaaatgg cgaaattgaa
    23221 ttgctctttg atgctagttt ggccttggaa cgtttggatg acctgtttgg agcagttcat
    23281 tcaagttcag accagctaac atctcaaaac cagctcaagg atttggtgga aaccttccag
    23341 caggagttgg gacgattgtt gacgcctttt gagattgagg atttgaccaa gacactaaag
    23401 gaagatggaa ccagtgctga cttgattaag gaggctcttc gtgaagctgt tttgaatgga
    23461 aaaccaaact ggaagtacat tcaggcgatt ttgagaaact ggcgccatga aggaatcaag
    23521 agtgtggctc aaattgaggc caagagagca gaaagagaag caagcaatcc tcagttgaca
    23581 caggtatctg cagatttcag aaatgccatg gatctctgga aggattaatc catgcaagta
    23641 ggcttgaaat ccgagtaaga tttgcaagct gtgtataatt gtgatagaat aaatagaaaa
    23701 taaattgaaa aaagaggtat gtgaaatgtc acgtaaacca tttatcgctg gtaactggaa
    23761 aatgaacaaa aatccagaag aagctaaagc attcgttgaa gcagttgcat caaaacttcc
    23821 ttcatcagat cttgttgaag caggtatcgc tgctccagct cttgatttga caactgttct
    23881 tgctgttgca aaaggctcaa accttaaagt tgctgctcaa aactgctact ttgaaaatgc
    23941 aggtgctttc actggtgaaa ctagcccaca agttttgaaa gaaatcggta ctgactacgt
    24001 tgttatcggt cactcagaac gccgtgacta cttccatgaa actgacgaag atatcaacaa
    24061 aaaagcaaaa gcaatctttg cgaacggtat gcttccaatc atctgttgtg gtgaatcact
    24121 tgaaacttac gaagctggta aagctgctga attcgtaggt gctcaagtat ctgctgcatt
    24181 ggctggattg actgctgaac aagttgctgc ctcagttatc gcttatgagc caatctgggc
    24241 tatcggtact ggtaaatcag cttcacaaga cgatgcacaa aaaatgtgta aagttgttcg
    24301 tgacgttgta gctgctgact ttggtcaaga agtcgcagac aaagttcgtg ttcaatacgg
    24361 tggttctgtt aaacctgaaa atgttgcttc atacatggct tgcccagacg ttgacggtgc
    24421 ccttgtaggt ggtgcgtcac ttgaagctga aagcttcttg gctttgcttg actttgtaaa
    24481 ataatcagta agtagcaaaa gctaggtgga acagcattca gatgtctgtt acatttttta
    24541 taggagagca aagattgaaa acaaaaattg gattagcaag tatctgttta ctaggcttgg
    24601 caactagtca tgtcgctgca aatgaaactg aagtagcaaa aacttcgcag gatacaacga
    24661 cagcttcaag tagttcagag caaaatcagt cttctaataa aacgcaaacg agcgcagaag
    24721 tacagactaa tgctgctgcc cactgggatg gggattatta tgtaaaggat gatggttcta
    24781 aagctcaaag tgaatggatt tttgacaact actataaggc ttggttttat attaattcag
    24841 atggtcgtta ctcgcagaat gaatggcatg gaaattacta cctaaaatca ggtggatata
    24901 tggcccaaaa cgagtggatc tatgacagta attacaagag ttggttttat ctcaagtcag
    24961 atggggctta tgctcatcaa gaatggcaat tgattggaaa taagtggtac tacttcaaga
    25021 agtggggtta catggctaaa agccaatggc aaggaagtta tttcttgaat ggtcaaggag
    25081 ctatgatgca aaatgaatgg ctctatgatc cagcctattc tgcttatttt tatctaaaat
    25141 ccgatggaac ttatgctaac caagagtggc aaaaagtggg cggcaaatgg tactatttca
    25201 agaagtgggg ctatatggct cggaatgagt ggcaaggcaa ctactatttg actggaagtg
    25261 gtgctatggc gactgacgaa gtgattatgg atggtgctcg ctatatcttt gcggcctctg
    25321 gtgagctcaa agaaaagaaa gattttaatg tcggctgggt tcacagagat ggtaaacgct
    25381 atttctttaa taatagagaa gaacaagtgg gaaccgaaca tgctaagaaa atcattgata
    25441 ttagtgagca caatggtcgt atcaatgatt ggaaaaaggt tattgatgag aacgaggtgg
    25501 atggtgtcat tgttcgtcta ggttatagcg gtaaagaaga caaggaattg gcgcataaca
    25561 ttaaggagtt aaaccgtctg ggaattcctt atggtgtcta tctctatacc tatgctgaaa
    25621 atgagaccga tgctgagaat gacgctaaac agaccattga acttataaag aaatacaata
    25681 tgaacctgtc ttaccctatc tattatgatg ttgagaactg ggaatatgta aataagagca
    25741 agagagctcc aagtgataca gacacttggg ttaaaatcat caacaagtac atggacacga
    25801 tgaagcaggc gggttatcaa aatgtgtatg tctatagcta tcgtagttta ttacagacgc
    25861 gtttaaaaca cccagatatt ttaaaacatg taaactgggt agcggcttat acgaatgctt
    25921 tagaatggga aaacccttat tattcaggag aaaaaggttg gcaatatacc tcttctgaat
    25981 acatgaaagg aatccaaggg cgcgtagatg tcagcgtttg gtattaagcg atgatttgaa
    26041 agagggatgt gatagtagca ccctcttttt ctttgtttta tgatagttca tcctcgagta
    26101 aattcaagat cttgctcgga aatgaagctt atatagtaga ttgaatatag acaaatacct
    26161 tgtgattggt aaaacatttt agaaattcat ttacctttcc taatcgactt ggtttcatct
    26221 tatttcaatc tattatagta ttggggaatt tcttcaaacc acatcagctt ggtcagttct
    26281 acctgcgacc tcaaaacttg tgctttggtc aagctgggtt tagtttccta gtttgctgat
    26341 ggatttccat tgactataag catccaaccc tctttttgtc ttctaaagaa ttcttaaatt
    26401 atcagtctat tgcaactttt ctcatataag ttctttgtct tgctattggt tttccttagt
    26461 agtatactaa ggtagtaatc attaagaagt ggttacaaaa aataatgaat gaggtaaaat
    26521 aaaatggtag aattgaaaaa agaagcagca aaagatgtcg caacattgac aaaagcagcg
    26581 ccagtagcat tggcaaaaac aaaggaagtc ttgaaccaag ctgttgctga tttgtatgta
    26641 gctcacgttg ctttgcacca agtgcactgg tatatgcatg gtcgtggttt ccttgtatgg
    26701 catccaaaaa tggatgagta catggaagct cttgacggtc aattggatga aatcagcgaa
    26761 cgcttgatta cactcggtgg aagcccattc tctactttga cagagttcct tcaaaacagt
    26821 gaaatcgaag aagaagctgg tgaataccgt aatgttgaag aaagcttgga acgtgttcta
    26881 gctatttatc gctacctcat cactcttttc caaaaagcgt tggatgtgac tgacgaagaa
    26941 ggcgatgatg ttacaaacga tatttttgtt ggtgctaagg ctgaacttga gaaaacagtt
    27001 tggatgcttg ccgcagaact tggacaagca cctggtttgt aagaaacaag acaacataga
    27061 taaatctgta ggaaatttct tacagatttt ttctattttg taagctattc caaaccagtc
    27121 tttttttgag ttttttgata aaatagtact atcagtgaaa aggatggaag catgactaag
    27181 aaaatcgtag ctatttgggc ccaggatgaa gagggtgtga ttggtaagga caatcgtctg
    27241 ccttggcatt tgccagcaga attgcagcac tttaaagaaa caactctgaa tcatgctatc
    27301 ttgatggggc gggtaacctt tgatggaatg gggcgtcgct tgcttccaaa acgggagacc
    27361 ctgattttga cgcgtaatcc ggaagaaaag atagatgggg ttgctacttt tcaggacgtc
    27421 cagtctgttc ttgactggta tcaggctcaa gaaaagaatc tctacattat cggtgggaag
    27481 caaatttttc aggcttttga agcttacctt gatgaagtga ttgtcactca cattcatgct
    27541 cgggtggaag gagataccta tttccctgaa gagcttgact tgtctctttt tgagacagtt
    27601 tcaagcaaat tttacgccaa agatgagaag aatccttatg attttaccat ccaataccgc
    27661 aagagaaagg aagtttaatg gaacggagtt tatttggtct attcacggct tttctgtgtt
    27721 tcatctgctt tctggcagga gcacaagctt ttcgtaaaaa gcgttacggg ctttctatcc
    27781 tcctttggtt aaatgccttt accaatctgg tcaatagtat tcatgctttt tacatgacct
    27841 tattttagat agaatgacag tatagaatgg aaggaaatca tgtctacaaa tagaaaaaat
    27901 gatatgatgg tttattgctc attttgtggc aaaaaccaag aagaagtaca aaaaataatt
    27961 gctggcaaca atgcttttat ttgtaatgaa tgcgtggagt tagctcagga aatcattcga
    28021 gaagaattgg ttgaggaagt cttggcagac ttgtctgagg tgccaaaacc aattgaactc
    28081 ctccatatct tgaaccacta tgtaattggt caagatcgtg ccaagcgtgc cttggcagtg
    28141 gcggtttata accactacaa acgcatcaat ttccacgata cacgcgaaga gtcagaagat
    28201 gtggatttgc agaagtcaaa cattttgatg attggcccaa ctggttcagg gaaaactttc
    28261 cttgcccaga ccttggctaa gagcttgaat gtaccttttg ctattgcgga tgcgacagct
    28321 ctgacggagg ctggttatgt gggtgaggat gtggaaaata tactcctcaa actcttgcag
    28381 gttgctgact ttaacatcga acgtgcagag cgtggcatta tctatgtgga tgaaattgac
    28441 aagattgcca agaagagtga gaatgtgtct atcacacgtg atgtttctgg tgaaggggtg
    28501 caacaagccc ttctcaagat tatcgaggga actgttgcta gcgtaccgcc tcaaggtgga
    28561 cgcaaacatc cacaacaaga gatgattcaa gtggatacaa aaaatatcct cttcatcgtg
    28621 ggtggtgctt ttgatggtat tgaagaaatt gtcaaacaac gtctgggtga aaaagtcatc
    28681 ggatttggtc aaaacaataa ggcgattgac gaaaacagct catacatgca agaaatcatc
    28741 gctgaagaca ttcaaaaatt tggtattatc cctgagttga ttggacgctt gcctgttttt
    28801 gcggctcttg agcaattgac cgttgatgac ttggttcgca tcttgaaaga gccaagaaat
    28861 gccttggtga aacaatacca aactttgctt tcttatgatg atgttgagtt ggaatttgac
    28921 gacgaagccc ttcaagagat tgctaataaa gcaatcgaac ggaagacagg ggcgcgtgga
    28981 cttcgctcca ttatcgaaga aaccatgcta gatgttatgt ttgaggtgcc gagtcaggaa
    29041 aatgtgaaat tggttcgcat cactaaagaa actgtcgatg gaacggataa accgatccta
    29101 gaaacagcct agaggtgact atggaactta atacacacaa tgctgaaatc ttgctcagtg
    29161 cagctaataa gtcccactat ccgcaggatg aactgccaga gattgcccta gcagggcgtt
    29221 caaatgttgg taaatccagc tttatcaaca ctatgttgaa ccgtaagaat ctcgcccgta
    29281 catcaggaaa acctggtaaa acccagctcc tgaacttttt taacattgat gacaagatgc
    29341 gctttgtgga tgtgcctggt tatggctatg ctcgtgtttc taaaaaggaa cgtgaaaagt
    29401 gggggtgcat gattgaggag tacttaacga ctcgggaaaa tctccgtgcg gttgtcagtc
    29461 tagttgacct tcgtcatgac ccgtcagcag atgatgtgca gatgtacgaa tttctcaagt
    29521 attatgagat tccagtcatc attgtggcga ccaaggcgga caagattcct cgtggtaaat
    29581 ggaacaagca tgaatcagca atcaaaaaga aattaaactt tgacccgagt gacgatttca
    29641 tcctcttttc atctgtcagc aaggcaggga tggatgaggc ttgggatgca atcttagaaa
    29701 aattgtgagg aaaagaaaat ggcaaaaaca attcatacag ataaggcccc aaaggctatc
    29761 ggaccctatg ttcaaggaaa aatcgttggc aaccttttgt ttgctagcgg tcaagttccc
    29821 ctatcccctg aaactgggga aattgtagga gagaatatcc aagaacagac agagcaagtc
    29881 ttgaaaaaca tcggtgctat tttggcagaa gcaggaacag actttgacca tgttgtcaaa
    29941 acaacttgtt tcttgagcga tatgaacgac tttgttcctt ttaatgaggt ttaccaaacg
    30001 gccttcaaag aggaattccc agctcgttca gctgtggagg tagctcgtct tcctcgtgat
    30061 gtaaaagtcg aaattgaagt catcgcagag attggataag ctagttgaag tttggtgttg
    30121 ccaaacttct tttgatataa ggagaaaaag atgacaaaga aacaacttca cttggtgatt
    30181 gtgacaggga tgagtggcgc agggaaaact gtagccattc agtccttcga ggatctaggt
    30241 tatttcacca ttgataatat gccgccagct ctcttgccta agtttttgca gctggttgaa
    30301 attaaggaag acaatcctaa gttggccttg gtagtggata tgcgtagccg ttctttcttt
    30361 tcagagattc aagctgtttt ggatgagttg gaaaatcaag atggtttgga tttcaaaatc
    30421 ctctttttgg atgcggctga taaggaattg gtcgctcgtt acaaggaaac cagacggagt
    30481 cacccactag cagcagacgg tcgtatttta gatggaatca agttggaacg tgaactcttg
    30541 gcacctttga aaaatatgag ccaaaatgtg gtggatacga ctgaactcac tccacgtgag
    30601 ctgcgcaaaa cccttgcaga gcagttttca gaccaagaac aagcccagtc tttccgtatc
    30661 gaagtcatgt ctttcggatt taagtatgga atcccgattg atgcggactt ggtctttgat
    30721 gtccgtttct tgccaaatcc ctattattta ccagaactga gaaaccaaac gggtgtggat
    30781 gaacctgttt atgattatgt catgaaccat cctgagtcag aagactttta tcaacattta
    30841 ttggccttga ttgagccgat tctgccaagt taccaaaagg aaggtaagtc cgttttgacc
    30901 attgccatgg gatgtacggg tggacaacac cgtagtgtgg catttgctaa acgcttggtg
    30961 caggacttat ccaagaattg gtctgttaat gaagggcatc gcgacaaaga ccgcagaaag
    31021 gaaacggtaa accgttcatg agaaaaccaa agataacggt gattggtgga gggactggaa
    31081 ttcccgtcat tctaaaaagt ctgcgggaaa aagatgtgga aatcgcagct atcgtgacgg
    31141 tggcagatga tggtggttct tcaggtgaac tccgaaaaaa tatgcaacag ttgacaccgc
    31201 caggtgattt tcgtaatgtc cttgtggcca tgtcggatat gcctaagttt tatgagaagg
    31261 tctttcagta tcggttctct gaggatgccg gagcctttgc tggccatcca ttgggaaatc
    31321 tcatcattgc tggcttgtca gaaatgcagg gttcaaccta taatgccatg cagttattga
    31381 gcaaattttt ccatacaaca gggaaaattt atccttccag tgaccatcct ttgacccttc
    31441 atgcagtctt tcaggatggg acagaagtgg ctggagagag tcatattgta gaccatcgag
    31501 gcataattga caatgtctat gtgaccaatg ccctaaacga tgatacgcct ctggccagcc
    31561 gtcgagtagt gcagaccatc cttgaaagtg acatgattgt cctagggcca ggttccctct
    31621 ttacctctat tttgcccaat atcgtgatta aggaaattgg gcgggctctt ttggaaacca
    31681 aggcagaaat tgcctatgtc tgcaatatca tgacccaacg tggggagacg gaacacttta
    31741 cagatagcga ccacgtggaa gtcttgcatc gtcaccttgg tcgccctttt atcgacactg
    31801 tcttggtgaa tattgaaaaa gtgcctcagg aatacatgaa ttccaaccgt tttgatgaat
    31861 acttggtgca agtggaacac gattttgtag gtctttgtaa gcaagtttcg cgcgtgattt
    31921 catctaactt ccttcgtctg gaaaatggcg gtgccttcca cgatggagat ttgattgtgg
    31981 acgagttgat gcgcattata caggtgaaaa aatgagtttc acagtagcag taaaagaaga
    32041 aatcctgggc caacaccatc tgagctggca tgaattatct gccattatca aaatgtctgg
    32101 tagcatcggt ctctcgactt cgggcttgac tttgtcagtt gtgacagaaa atgccaaact
    32161 ggcccgtcac ctctatgagt cctttctcca tttctatgaa atcaaatctg aaattcgtca
    32221 ccaccaacgg agcaatcttc gcaagaatcg cgtctatacc gtttttacag atgaaaaggt
    32281 gcaggatttg ttaagtgatt tgcacttggc agactctttc tttggcctgg aaacaggtat
    32341 tgatgaggcg attttatcgg atgaggaagc aggtcgtgcc tatctctgtg gcgctttctt
    32401 ggcaaatggg agcattcgtg accctgagtc aggcaagtac cagttggaaa tcagttctgt
    32461 ttatctggac cacgcgcaag gaattgcctc ccttctccaa cagtttttac tggatgccaa
    32521 ggtgcttgag cgcaagaagg gggctgtgac ctatctccag cgagcagaag acattatgga
    32581 cttcttgata gtaatcggag ccatgcaggc acgtgatgat tttgagcggg ttaagatttt
    32641 gcgagaaacc cgtaacgacc tcaatcgggc taataatgcc gagacagcta atatcgctcg
    32701 gacagtttct gccagcatga agaccattaa caatatcagt aaaatcaaag atatcatggg
    32761 cttagaaaat ttgccagtag atttgcagga agtggcgcaa ctgaggattc agcacccaga
    32821 ctactctatc cagcagttag cagatagtct cagcacccct ctgaccaaaa gtggtgtcaa
    32881 tcacagactc agaaaaatca ataagatagc ggatgaatta taaaaccacg aatcctatgt
    32941 gactcgtggt tcttttttat aaactggtag agtgttttgg ttgtactttt tgttcagggt
    33001 aaatgtagtt gatagcgttg ttgacagcag ttggagcttc tccgaggcct gtcgcaatca
    33061 gatcaatttt tccgtcatag tagcagcagt caccgatagc atagatacct gcttggctgg
    33121 attcctgttt gctgtttacg ataatcttgt gacggttgag gtcgagcccc cagtttttaa
    33181 ggttaccgac agaagatttg aaaccatagt tgacaaagag gtggtctagg tcaatggttt
    33241 cagtttcatc agatttgact tttgtgattt caagtttatc aagtgttttt ccatttccaa
    33301 ggagttggct aggggcgaat ggtgtcttga tggttacaga tgattcttgc aaggcttgaa
    33361 cactgtgttc caaggcacgg aaattatctc tgcggtgaac aagggtagtt ggtgcgattt
    33421 tttcaaaagc caaagtccaa tccacagccg agtctccccc gccaagaatc gtcactttct
    33481 taccagcgta ttgctgaatg ttagaaacgt ggtagtggat attttcatag ccctcaaccc
    33541 cttcaagttc cagcggacgt ggtttgaagg caccgccacc catagcaatg ataactgttt
    33601 tagtcaggtg acttccttta gaagttgtga tggcaaattc ttcttcttgt ttgtcaattt
    33661 caagaaccgt ttcattgaga tgaatagggg tatcaaatcc atttagctgt tcaatcaagc
    33721 ggttagtcaa ctcttctcca gtcaggtttg ggaagcctgg tacgtctagg atttcctttt
    33781 cagggtagag aatagcaggt tgtccaccta gctggggaag agagtcgatg atttgaacct
    33841 tggcttggcg taggtgggca taaaaggctg caaaaagccc gacaggacca ccacccacaa
    33901 tggtaatatc atagagttga gacatagttt ctcctttgtt ttttctagtc agtttatttt
    33961 atcatatttt tgttcaatgt aaaatggact aggataggga aaaaaatgcc agaaaatggt
    34021 ataataggac gaaagtgttt tgatagggag gatatcaggg atgaattttc aacaattatc
    34081 caatctgcaa tattggacca gtttgtttgc aagtccatgg acgatagcta tcaatctgat
    34141 tgatattttg attgttgctt atattttata ccattttaca aaagctattg caggaaccaa
    34201 gattatgatt ttggtacgtg gagttttggt gtttatttta gctcaaatcc ttgcaaatat
    34261 gattggtttg actacgattt cttggttaat caatcaaatt attacttatg gggttattgc
    34321 ggcggttgtt atcttctctc cagagattcg gactggtttg gaacgtttgg gaagagcgac
    34381 agatttcttt tccaatgccc ctattagtgc tgaggaacag atgattcgtg cctttgttaa
    34441 gtctgttgaa tacatgagtc ctcgtaaaat cggggccttg gttgctattc agcgtgtacg
    34501 taccttgcag gagtatatgt cgacaggaat tcccttggat gctaagattt ctgcagaact
    34561 tctcattaac atttttattc ccaacactcc cctacatgac ggtgcggtga ttatcaaaga
    34621 agaacgtatc gctgtgacgt ctgcctatct gcccttgaca aaaaacacag ggatttccaa
    34681 ggaatttggg accagacacc gggcggctat cggtttatca gaagtctcag atgccttgac
    34741 ttttgtcgta tcagaggaaa cgggaggaat ttcgataacc tataatggaa ggtttaagca
    34801 caacctaaca cttgatgaat ttgaaacaga attacgtgaa atcttacttc caaaagagga
    34861 agtgggtctt agttttaaag aacgattgct aggaggatgg aaacatgaaa aaaaatagtt
    34921 tatatatcat atcctcactc ttttttgctt gtgtcttatt tgtctatgct acggcgacga
    34981 attttcaaaa cagtaccagt gctaggcagg taaaaacgga aacctatact aatacagtaa
    35041 caaatgtccc tattgacata cgctataata gtgataagta ttttattagc ggttttgctt
    35101 cagaagtatc agtggtcttg actggtgcaa atcgtctatc gctagctagt gaaatgcaag
    35161 aaagtacacg taaattcaag gttactgctg acctaacaga tgccggtgtt ggaacgattg
    35221 aagttccttt gagcattgaa gatttaccca atgggctgac cgctgtggcg actccgcaaa
    35281 aaattacagt caagattggt aagaaggctc agaaggataa ggtaaagatt gtaccagaga
    35341 ttgaccctag tcaaattgat agtcgggtac aaattgaaaa tgtcatggtg tcagataaag
    35401 aagtgtctat tacgagtgac caagagacat tggatagaat tgataagatt atcgctgtct
    35461 tgccaactag cgaacgtata acaggtaatt acagtggttc agtacctttg caggcaatcg
    35521 accgcaatgg tgttgtctta ccggcagtta tcactccgtt tgatacaata atgaaggtga
    35581 ctacaaaacc agtagcacca agttcaagca catcaaattc aagtacaagc agttcatcgg
    35641 agacatcttc gtcaacgaaa gcaactagtt caaaaacgaa ttaaaaatag aaaaggattt
    35701 tataacaatg ggtaaatatt ttgggactga tggagtccgt ggagaagcta acctagaact
    35761 aacaccagaa ttagccttta aactaggacg ttttggaggc tatgttctta gtcaacatga
    35821 aacggaagcg ccgaaagtct ttgtaggacg tgacacacgt atttcagggg aaatgctgga
    35881 atcggccttg gtggcaggtc tcctttcagt agggattcac gtatacaaac ttggtgtcct
    35941 tgcaacacca gcagtagctt acttggttga aactgaagga gcaagtgccg gtgtcatgat
    36001 ttctgctagc cacaacccag cccttgataa cggaatcaag ttctttggcg gtgatggctt
    36061 caaactagat gatgaaaaag aagcagaaat tgaagccttg ctagatgctg aggaagacac
    36121 tcttcctcgt ccaagtgcag aaggtttagg aattttggta gattatccag aaggcttgcg
    36181 taagtatgaa ggataccttg tttcaactgg aactcctctt gatggaatga aggttgcctt
    36241 ggatacagct aatggagcag cttctaccag tgcccgtcaa atctttgcag accttggtgc
    36301 ccaattgacg gttatcgggg aaacaccaga cggtcttaac atcaacctta atgttggttc
    36361 aacacatcca gaagcccttc aagaagtggt caaagaaagt gggtcagcta ttggtttggc
    36421 ctttgatgga gacagtgacc gcttgattgc tgttgatgag aatggtgaca tcgtcgatgg
    36481 tgacaagatt atgtacatca tcggaaaata cctttctgaa aaaggacaat tggctcaaaa
    36541 tacaattgtg acaactgtta tgtctaacct tggtttccac aaggccttga atcgcgaagg
    36601 tattaacaag gcagttactg cagttggtga ccgctacgtt gttgaagaaa tgagaaaatc
    36661 aggttacaac cttggtggtg aacagtctgg tcacgttatc ttgatggatt acaataccac
    36721 aggtgatggt caattatcag cagttcaatt gactaaaatc atgaaggaaa ctggtaagag
    36781 cttatcagag ttggcggcag aagtaacgat ttatccacaa aaattagtta atatccgagt
    36841 ggaaaacgtc atgaaggaaa aggccatgga agtgccagct atcaaggcca tcatcgagaa
    36901 gatggaagaa gaaatggcgg ggaacggccg tatccttgtt cgtccaagtg gaacagaacc
    36961 cctcttgcgt gttatggcag aagcgcctac aacagaagaa gtagactact atgttgatac
    37021 catcacagat gtagttcgtg ctgaaattgg gattgactaa atcctagaaa actagatgaa
    37081 aataaaaaat tatggtacaa tagcttataa tattgtagcc gatggagaaa gacatgaatc
    37141 ttaaacgtga acaagaattt gttagtcagt atcattttga tgcgcgtaat tttgaatggg
    37201 aaaatgaaaa tggagctcct gaaaccaagg tggatgtgaa tttccaattg ctccaacatg
    37261 accaagaaaa tcaagtgact tccttgattg tcatcttgag ctttatgatt gtatttgata
    37321 agtttgtcat tagtggaaca atctcacaag taaaccatat cgatggccgt attgtcaatg
    37381 aaccaagtga attgaaccaa gaagaggtgg aaaccttggc tcgtccatgt ttgaacatgc
    37441 tcaatcgttt gacttacgaa gtgactgaaa ttgcattaga cttaccagga attaatttgg
    37501 agttctaata tgaaattagc tgttttcaca gattcctctg cttatctcag tgcagagacc
    37561 ttgcaaagag aagacttgtt tgtcttggat attcctgtca atattgatgg tgaggaatat
    37621 gtcgaaggca tcaatctgtc tgctgaggaa ttttaccaaa aaatggctca ggcttctgaa
    37681 ttgcctaaga ccagtcaacc aagtattgcc aagttagatg aaatcttaac ttcgctcaaa
    37741 gaacaaggct atacacatgc cttggggctt ttcctatctt ctggaatttc aggtttttac
    37801 caaaatatcc agtatatggt cgatgactat gagggcttaa ccattgcttt cccagacact
    37861 ttgattacaa gtgctcccct aggcatcatg gttgaaagcg tctttaattg gcgtgatcag
    37921 ggcgatgatt ttgccagcat tcaggataag ctagccattc aaatcagccg tacgtcagcc
    37981 tttatcatgg tagatgactt ggatcatttg gtaaaaggtg gacgcctttc aaatggggct
    38041 gccattttgg gcaatttgct tagcattaag ccaatccttt attttaacga tcaaggtgtg
    38101 attgaagttt acgaaaaagt tcgtactgaa aagaaggcca ccaaacgctt aattgaaatt
    38161 atcaaggaaa caacggcttc aggtcaatac cgggtcattg tcattcatgg gaatgctcct
    38221 gaaaaggctg aagaattgcg tcagcatttg cttgattttg gcttgggttc ggatgtttca
    38281 cttgctacat ttggtagtgt cattggaacg cacctaggag caggaagtat tgctctgggt
    38341 tatattccag tgatttagta ggcacttcta ggctagttaa tcttagcaat tgaacacgga
    38401 ctacctgcct cttgaaaaaa gatgtctgtc ttgcctttcg tggaaagtca gtgccattcc
    38461 ctatttttca tgggtggcta agatcctttg tatcttgata attgaacacg cctggaaccc
    38521 tgtgtgaaaa agatagttct tccaaggagt agacacttct tgatcagaat tcctattttc
    38581 actttgtgtt cttacaggct ttgtatctta gacaggagta gagatgagta ttcgagtaat
    38641 tattgccggt tttaagggaa agatgggtca agctgcttgc cagatggtct tgactgattc
    38701 agatttggac ttggtagcag ttttggatcc ttttgagtct gagtcagaat ggcagggtat
    38761 tcctgttttc aaggataagg ctgatttagc tggttttgaa gcggatgtct gggtagactt
    38821 tactactcca gctgttgcct acgaaaatac acgttttgct cttgaaaatg gctttgctcc
    38881 agtagttgga acgactggtt tcacgagtga agaaattgca gagctaaaag aattttctcg
    38941 tgcccaagac ttgggtggcc tgattgcccc taactttgcc ttgggtgctg tcttactcat
    39001 gcaatttgcg acgcaggctg ccaaatattt cccaaatgtg gagattattg agctccatca
    39061 tgacaagaaa aaggatgctc cgagtggaac agccattaaa acagctgagt tgatggcaga
    39121 ggttcgagag tcaattcagc aaggtgcagc agatgaggaa gagctgattg ctggtgctcg
    39181 tggtgctgac tttgatggta tgcgcatcca ctcagttcgt ttgccaggtt tggtagccca
    39241 tcaggaagtc atctttggca atcaaggaga aggattgacc ctccgtcatg actcctatga
    39301 tcgcatctcc ttcatgacag gagtcaattt gggaattaaa gaagttgtca agcgtcatga
    39361 gcttgtctat ggattagaac acttattatg agattaacgc aaatgccttc tgaatttcag
    39421 aaggctttac cagtattaga aaaaattaaa gaagcaggct ttgaggctta ttttgttggg
    39481 ggctctgttc gagatgccct tctccatagc cctatccacg atgtggatat tgcgacgtct
    39541 tcttatccag aagagaccaa gcagattttt ccgcgaacag ccgatatcgg aatcgagcat
    39601 ggaaccgtct tggtcttaga tggggatgag gagtatgagg taacaacctt tcggacagag
    39661 gatgtctatg tggactatcg cagacccagt gcggtttcct ttgtgcgctc gctagaagaa
    39721 gacctcaaac gccgtgattt cacagtcaac gcctttgcct tggatgagac aggagaaatc
    39781 gttgacttgt tccatggttt agaagatttg gaaaagcaag tcttgcgagc agttggagtg
    39841 gctagtgagc gtttcaacga agatgcttta cggattatgc gtggtttccg ttttcaggct
    39901 agtcttggtt ttgcacttga gccagaaaca tttaaagcta tgaagacctt gacgccgctt
    39961 ttggagaaaa tttctgtaga gcgtaccttc gtcgagtttg ataaactctt gctggctcca
    40021 ttttggagaa ggggcttggc ttccatgatt gagagtcaag cttatgacta tctccctgat
    40081 atggcatcta gccagaacaa gctcaacaga ctgtttgatt tggagactga ttttactttt
    40141 gaatcctctg aacaagcctg ggcggcttta ctatgggctt tggagattga aaatgcgcag
    40201 tcatttttga aatcttggaa gacctcacgc cagtttgcca agcaagttca ggatttgctg
    40261 attattttgg ctctgcgtga aaatggagaa ttgagcaagc gagattgtta tcgctttgac
    40321 atagatttgc ttttacaggc tgaaaatctt cgtcaagctc gaggaaaaga agtcaaccca
    40381 caagccatca cagaaaaata ccaaagcttg actatccatg acaagaaaga tattcagatt
    40441 aatggcgata ttttgatcaa ggaatatggc tatcagccag gcccagactt gggagagatt
    40501 ttaacagaga ttgagtttgc cattgtcgat ggagaattgg agaataatcg tgaagccatc
    40561 catgcttacc tgagggagaa aaaatgagtg attttatcgt tgaaaaacta agtaaatccg
    40621 ttggtgacaa gaccgttttt agggatattt cctttattat ccatgactta gacagaattg
    40681 gtttaatcgg tgtcaatggg actggcaaga ccaccctttt ggacgtcctt tctggtgttt
    40741 ctggctttga tggggatgtc agtccttttt cagctaaaaa tgattaccag attggttact
    40801 tgactcagga tcctgatttt gatgatagaa agacagtttt ggatacggtt ctatctagtg
    40861 aactcaagga aatccagctc attcgtgagt atgaattgat tatgctcgac tatagtgagg
    40921 acaagcaggc gcgtttggaa cgtgtcatgg cagagatgga ctctctccaa gcttgggaaa
    40981 tcgagagtca ggtcaagacc gttcttagca aattgggcat tcaagactta tctactcctg
    41041 ttggggaatt gtcaggtggt ctgagaagac gggtacagtt ggcacaagtc ttacttggta
    41101 accacgacct cttgcttttg gatgagccga ccaaccatct ggatattgcg attattgagt
    41161 ggctgaccct ctttttgaaa aattctaaga agaccgtcct ttttatcact cacgatcgtt
    41221 atttcttaga cgctttgtca acacggattt tcgagttgga tcgtgcaggc ttgaccgagt
    41281 accggggaaa ttaccaggac tatgttcgcc taaaggcgga acaggatgag cgcgacgcgg
    41341 ctcttcttca caaaaaagaa caactctaca aacaagaatt ggcctggatg cgcagacaac
    41401 cgcaggcgcg tgcgaccaag cagcaggccc gtatcaatcg attccatgat ctgaaaaagg
    41461 aagtttcagg cagtagtgct gagacagact tgaccatgaa ctttgaaacc agtcggattg
    41521 ggaagaaagt catcgagttt caggctgttt cctttgccta tgaaaacaag cctattttgc
    41581 aagattttaa tctcttggtg caggccaaag accgtatcgg aatcgttggg gacaatggtg
    41641 ttggaaaatc aaccctgctc aacttgattg caggaagtct tgagccaact aaaggacaag
    41701 ttgtgattgg ggaaactgtt cgcatcgcct atttctctca gcaaattgag ggtttggatg
    41761 aaagcaagag agttatcaat tacctgcagg aagtggcaga agaggtcaag accagtggcg
    41821 gttctacgac ttcgattgca gagttgctgg agcagttcct tttcccacgt tcgacgcatg
    41881 gaaccttgat tgagaaattg tcagggggtg agaaaaaacg tctttatctc ctcaaactgc
    41941 ttttggaaaa accaaatgtt cttcttttag acgagccaac caatgaccta gatattgcaa
    42001 ctttgacagt cttagagaat ttcttgcaag gttttgcagg tcccgtttta acagtcagtc
    42061 acgaccgcta tttcttggat aaggtagcga ccaagattct cgcttttgag gatggcaaga
    42121 ttcgtccttt ctttggtcat tacaccgact atcttgatga aaaagctttt gaaacagata
    42181 tggccaatca agtgcaaaag gccgaaaagg aaaaagtggt caaggttcga gaagacaaga
    42241 aacgcatgac ctaccaagaa aagcaggagt gggcaagtat tgaaggtgat attgaagcct
    42301 tggaaaaacg tatcgctgct attgaagagg aaatgcaggc taacggctct gactttggta
    42361 agctggctac tctccaaaaa gaattggatg agaaaaatga agcactcctt gaaaaatacg
    42421 aacgctatga gtatctcagt gaatttgata gttgatacta ttcgaaaatc aaagtgcaaa
    42481 ctatgtcggc ttcacattgc cgactcaagt acagcctgtg accggcttcc taatttgcac
    42541 tttgattttt attgagtata aacgaataga aaaatcccgt ctcatgaaag gatttctcta
    42601 ttcttttttg gtttcttgat gaaagatatt ttgccaggtt tcgtggcgac gccagatact
    42661 ggtatggatg ataccatcta actcatagca gataagtttg gttttttgac tgatggaagt
    42721 aatttgaatg tccttgatag cagaatttaa ctcttttttg gtcttataag cctctttatc
    42781 catctgctct ccatcttggc gaatatagac aaaatcatca gtcaagagtt cttctagttg
    42841 gtttccttgg tcgatcaatt gttcacgcat aagcaatttt ttatagacat tgtctaaaat
    42901 ttcatcctca gggataggtg ctggttcgat atggacatcg gtatcaaaga cgccaaaacg
    42961 attctccagc atagactcga cctgatccgc gatttcatgg ctttcaaaaa cagacaagtc
    43021 aggattcatc tctagtgtaa tatccaggta gatgttgcta ccgtaggtgc gacctctttg
    43081 cgatttgacc ttgctgattt tgggaatttc catgatagcc ttttggtagt cctcgagcag
    43141 gcggtcgtca aagccatctg aaagactaaa ggaagactcg atgaagatat cataggcagt
    43201 cttcaagata aagaaagtga tgatgatagc aaccagttta tccacaatcg gataattgaa
    43261 actactagct aggatggcaa tggcggttcc aagtgaggta acagcgtcag aaagattgtc
    43321 cttagcagct gccttcagcg ccttggagtt ggatttctta ctgaggcgag tattgtagag
    43381 atagaccaca aacataatcg ctgcagaaat gattcctaga gttgcaccaa gaggatcaat
    43441 gaccgtttct tcccgactga gaatcttttg aatggtatct cttagaacat cgaaaccgac
    43501 atagaacatg atgatagaag tgatcaagct tgccaaatct tcaatcttcc aatgaccaaa
    43561 acggtggtca cggtctgcag gctggcgcgc catccgaatc ccgattaaga gggccacatt
    43621 tccaatgatg tccgatacgt tattaaaacc atcggccacc aaactggatg aatgaaggag
    43681 atgaccagct gctaatttgg ctgcagacaa gatcaaatag gtcgaaatac tgataatggc
    43741 tccacgctca gctaacttga gatttgagat agattgcttc attcaacttc ctttctagtc
    43801 acatagcatt ctaccattat actggttttc aaggaaaaat tcaaataagg cagtttttac
    43861 tctttgaaaa ctccccaaaa tttggtataa tggtactact caagggagta gctggcagaa
    43921 acctgtgata gtgtcgtcat tccgaatttt atgctgaaaa gtatgctttc cggccctatc
    43981 ttaaacagcg agacttgtta tgattaacag gtctcttttt gtttgtcgtg aaaagatatg
    44041 acagaaagag agtctgtttt gcacacaatg tcaaggagga gacacatgtc aaaagaacaa
    44101 aaacgccaag cgttttatac tcagagccct gaagaggtct tgcaggctgt ggatgcgacc
    44161 gagcaaggtt tgtcatcaag tgaggcggaa aagcgccttg ccgaatttgg gcacaatgaa
    44221 ctcgaagaag gcgagaaacg atcaatcttg gtcaaattca tcgagcaatt taaggatttg
    44281 atgattatca tcctagttgc ggcagcaatc ttgtcagtcg tgacttctgg tggggaagat
    44341 atcgcagatg ccattatcat cctagctgtg gttatcatca acgctgcctt tggtgtttac
    44401 caagaaggaa aagctgaaga agctattgaa gccctcaaat ccatgtctag tccagttgcc
    44461 cgcgttcttc gtgatggaca catggcagag attgactcta aagaattggt accaggcgat
    44521 atcgttgccc ttgaagcagg tgacgtggta ccagcggacc tacgtttgat agaagccaac
    44581 tctcttaaaa ttgaagaagc agccttgaca ggtgaatctg taccagtcga aaaagacttg
    44641 tcagtcgagc ttgcgacaga tgctggtatt ggtgaccgtg tcaacatggc cttccaaaac
    44701 tcaaacgtaa cctatggtcg tgggatgggt gttgttgtca atacaggtat gtacactgaa
    44761 gttggtcata ttgctggtat gcttcaagat gcggatgaga ctgatacacc actcaaacaa
    44821 aatttgaaca acctttctaa ggtcttgacc tatgctatct tggtcattgc ccttgttact
    44881 tttgtagtgg gtgtcttcat tcaagggaaa aatccacttg gtgagttgtt gacttctgtt
    44941 gcccttgccg ttgcagccat tccagaagga cttcctgcta tcgttaccat cgttctttct
    45001 cttggtactc aagttttggc caaacgacat tccatcgttc gtaagttgcc agcagttgaa
    45061 acacttggtt caactgaaat catcgcttct gataagactg gtacgctgac tatgaacaag
    45121 atgacagtcg aaaaagtctt ctacgatgcg gttctacatg actcagctga tgatattgaa
    45181 ctaggtcttg aaatgccact acttcgttca gttgtcttgg ccaatgatac gaaaatcgat
    45241 gtggaaggta acttgattgg tgacccaacc gaaacagcct ttatccaata tgccttggac
    45301 aagggctatg atgtcaaagg tttcttagag aaatatcctc gtgtagctga attgccattt
    45361 gactctgacc gtaagctcat gtcaacagtt cacccattgc cagatggtcg tttccttgta
    45421 gcagtcaagg gtgcgccaga ccaactctta aaacgttgtc ttcttcgtga taaggctggg
    45481 gatattactc cgattgatga gaaggttaca aatctcattc atacaaacaa ttctgaaatg
    45541 gctcatcaag ccttgcgtgt ccttgcaggt gcttataaga ttatcgatag tattccagaa
    45601 aatctcactt ctgaagagct tgaaaatgat ttaattttta ctggtttgat tgggatgatt
    45661 gaccctgaac gtcctgaagc cgctgaggct gttcgtgtgg ctaaggaagc gggaatccgt
    45721 ccaattatga ttacaggtga ccaccaagac acagcggaag ccattgccaa acgtttggga
    45781 atcattgacg caaacgatac agaaggtcac gttttaactg gtgctgaact caatgaactg
    45841 tcagatgaag aatttgaaaa agtcgttggt caatactctg tttatgcccg tgtgtctcca
    45901 gaacacaagg ttcgtatcgt caaggcttgg caaaaacaag gtaaagtcgt tgccatgaca
    45961 ggtgacggtg tcaatgacgc gccagctctg aaaacagccg atatcggtat cggtatggga
    46021 atcactggta cagaggtttc taagggggct tctgatatga ttcttgcaga tgataacttt
    46081 gcgactatta tcgtcgcagt ggaagaagga cgtaaggtct tctcaaacat tcaaaagact
    46141 attcagtacc tactttctgc taatactgct gaagtattaa ccatcttcct atcaaccttg
    46201 tttggttggg atgtcttaca gccggttcat cttttgtgga tcaacttggt aacggatacc
    46261 ttcccagcta tcgctcttgg tgttgaacct gcggaacctg gtgtcatgaa tcataaacca
    46321 cgtggacgca aggcaagctt cttctcaggt ggtgttttga gttctatcat ttatcaaggt
    46381 gtactccaag cagctcttgt tatgagtgtt tatggccttg cgattgctta cccagttcat
    46441 gtgggtgaca atcatgctat tcatgcagat gccctaacga tggcctttgc aacccttggt
    46501 ttgattcagc tcttccatgc ctacaatgtc aagtctgtct accaatccat cttgacagtt
    46561 ggcccattca agtctaagac ctttaactgg tccatcttgg tatcctttat ccttctcatg
    46621 gcaacaatcg ttgtagaacc gcttgaagga atcttccacg taaccaaact agacttgtca
    46681 caatggggaa ttgttatggc tggaagcttc tcaatgatta tcatcgtcga aatcgttaag
    46741 tttattcaac gcaaactcgg ttttgacaag aatgcgattt aagggaggtt tcggatgtca
    46801 gcatatcaat taccgaccgt atggcaggat gaagctagta atcaaggagc ttttacgggg
    46861 ctaaacagac caacagcagg tgcccgtttc gaacaaaact tgccaaaagg agaacaagct
    46921 tttcagcttt attcactggg aacaccaaat ggtgtgaagg ttactatctt attggaagaa
    46981 ttactagaag ctggttttaa ggaagcggct tacgacttgt ataagattgc tatcatggat
    47041 ggggatcaat tcggctcaga ctttgtgaag ctcaatccaa attccaagat tccagcctta
    47101 ttggaccagt caggtactga aaacgtaaga gtctttgagt ctgctcatat tcttctttac
    47161 cttgctgaga aatttggagc ctttttacca agtaatcctg tggaaaaggt agaagttttg
    47221 aattggctat tctggcaagc aggtgcagca ccttttctag gtgggggatt tggacatttc
    47281 ttcaattatg ctcctgaaaa attggaatat cctattaacc gttttacgat ggaagtgaaa
    47341 cgccagttgg atttattgga taaggaattg gctcagaaac cttatattgc aggcaatgac
    47401 tatacgattg cagatattgc tatctggtct tggtatggac agttagttca aggaaatctt
    47461 taccaaggtt ctgcaaaatt cttggatgcc tcaagttatc aaaatctagt aaaatgggca
    47521 gaaaaaattg ccaatcgtcc agctgttaag cgtggcttgg aagtaactta tacagaaatt
    47581 aaatagcaaa aaagtcatct tcggatggct ttttgctaca gttgagggaa agggtttgca
    47641 gttatcggct tttgtgctat aattgctata atatagtaaa aagcaagagg agtgtgagga
    47701 agtggaaaag aaaattgtga aggatatctt atttttatct caagtgtctc agccggcaag
    47761 tcaggaggac ctttatcttg ccagagattt gcaggataca ctcttagcaa atcgtgatac
    47821 ctgtgttggt ctagctgcca atatgattgg ggtgcagaag cgcgtgatta tctttaatct
    47881 tggcttggtt cccgtggtca tgtttaaccc agtgcttctg tcctttgaag gatcctatga
    47941 ggcagaagaa ggctgtttgt ccttggtagg tgtgagatca actaagcgtt atgaaaccat
    48001 aagggttgcc tatcgtgaca gcaagtggca ggaacagacc attaccttga caggcttccc
    48061 agctcagatt tgccagcatg agctggatca cttggaagga cgaatcattt aggaggaaag
    48121 caaatgaaac gaatagtctt tgaacttatt tttatcgcaa cgacctggta tatcttttta
    48181 ccgcccctta acctgaccag ctgggaattt ctcttcttcc tctgtgggca tttgttagtt
    48241 gtggcaatct tatttggctt tggcaagggg ataaaccttg tcaaaacggt tcatgtgcgc
    48301 cacggtaagg cggaagctgc cttaaatctt gagggtttca aaatcaatcg gttagggaaa
    48361 attctgttag cttcgattgg aggaattctt ctcttggcag ctttggtttc cttggtaact
    48421 tccagcatgt ttcaggctaa aaattatgcc aatgtagtca cggttacgga aaaagacttt
    48481 actgaatttc ctaagagtga caccagtaag gttcctatcc tagatagaag tactgctgaa
    48541 aaaattggag accgctactt gggttcccta accgataagg tgtcgcaata cgtagcggca
    48601 gatacctata cccaattgac aattgatggg aaaccttatc gggtcacacc actagaatat
    48661 gcagacccta tcaaatggtt taacaatcaa gccaagggaa tcggtgagta tatcaaggta
    48721 gacatggtaa ctggaaatgc ggatttggtg gacttgaaga caccaatcaa gtattcagac
    48781 tcggagtatt ttaaccgtga tgtcaaacgt cacctgcgct tgaagtaccc gaccaaaatc
    48841 tttaaaactc catcttttga ggtgaacgat gagggcaatc ctttctatgt agcaacggtt
    48901 taccaaaagc aatttggact tgcggttcct cgtcctgctt cagtcattat cttggatgct
    48961 acaaatggag aaaccaagga atacagctta tcagatgttc cagaatgggt ggacaggatc
    49021 tatccagcag aggaaaccat tgagcaaatc aactacaacg gcaagtacaa ggacggtttc
    49081 ttgaatgcca tgatttccaa gaaaaacgtg acccagacta ccaatggcta taattacttg
    49141 tctatcggta atgacatcta tctctacaca ggtgtgacgt cggctaatgc ggatgagagt
    49201 aatcttggtt tcatccttga aaatatgcga acaggagaaa ttactaagta tagcttggct
    49261 tctgcgacag aagaatcagc ccgtgaatca gcagaaggtg ctgttcagga gaaatcctac
    49321 aaagcaacct tcccaatcct catcaacctc aatgacaagc ctctctacat catgggctta
    49381 aaggacaatg ctggcttggt caaagagtac gccctggtag acgcagtcga gtaccaaaat
    49441 gttatcgttg ctactacagt ggaagagatg ctcagcaagt atgccaataa aaacgacctt
    49501 gaaattgaca atgcaacgac agaaagcatc aagggagtag tagcagacct caaatcagct
    49561 gttatcaagg gagacactgt ctacttcttt aaagttgatg gcaagatata caaggtaaag
    49621 gcttcagtat ccgatgacct tccttacctt gaaaatggta aaaccttcga aggtcaagta
    49681 ggaaaagaca attatctcaa gacctttaaa gtacaataat actcttcgaa aatctctagc
    49741 tctatctgca acctcaaaac agtgttttga gcagcctgcg gctagtttcc tagtttgctc
    49801 tttgattttc attgagtata aaaaaggttt atttaataaa tatatgttat aataaggtaa
    49861 attaagccta atggaggaca aagaaatggg tttttatttg atggttgctt caatgctact
    49921 cggactgctc gctttgaaga taggtttttc tcagttcaag gagaaaaaag ataaattctt
    49981 atctatctta acaagtttag ctggcatagc ccttgttctc gcggctgtct ggttaggatg
    50041 gcccaaataa atagaaaaac ctctgtcaaa ccgaggtttt tcaaatgaat ttcttggttg
    50101 tggctaaaaa atatgctaca ctatcaatat gaaaatttta atcccaacag caaaagaaat
    50161 gaacacagac ttgccaagta tcgaggcaat tcctttaaaa ccagaaagtc agaccgtgct
    50221 tgatgccttg gctctctatt ctgccagtca attggagagt ttctacaagg tatcagctga
    50281 gaaagcggcg gaagaatttc aaaatatcca agctttgaaa aggcaaactg ctcaacacta
    50341 tccagccttg aaactttttg atgggcttat gtaccgcaac attaagagag ataagctgac
    50401 cgaggcggaa caagattatc ttgaaaatca tgtcttcatt acctcggctt tgtacggtgt
    50461 tgttccagcc ttgtcaccca tggctcctca ccgtttggat tttttgatga aattaaaagt
    50521 cgctggtaag actttgaaga gccattggaa ggcagtctat gatgaagctc tgaagaagga
    50581 agaagtgatt ttctctctct tgtcatcaga gtttgagact gtattttcta aggaaatcag
    50641 agcaaagatg gtgaccttca aattcatgga ggatagaggc ggtcagctga agattcactc
    50701 aactatctcc aagaaagcgc gcggggcctt tctaacagct ttaatagaaa atcaagtaca
    50761 aactgtgggg gaagcacgtc gcttgaactt tgctggattt gtttaccgag aagatttgtc
    50821 acaaccacag ggattggttt ttgtaaagga agtatagaaa tcagataaga gaaaa
//
LOCUS       DBERXF010000010        50064 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.10, whole genome shotgun sequence.
ACCESSION   DBERXF010000010 DBERXF010000000
VERSION     DBERXF010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 50064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50064
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.10"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(166..2271)
                     /locus_tag="ACL8JK_000670"
     CDS             complement(166..2271)
                     /locus_tag="ACL8JK_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS1785600.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLAAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQAIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(2880..3860)
                     /gene="mraY"
                     /locus_tag="ACL8JK_000671"
     CDS             complement(2880..3860)
                     /gene="mraY"
                     /locus_tag="ACL8JK_000671"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGS1785601.1"
                     /translation="MFISISAGIVTFLLTLVEIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(3862..6114)
                     /gene="pbp2X"
                     /locus_tag="ACL8JK_000672"
                     /gene_synonym="pbpX"
     CDS             complement(3862..6114)
                     /gene="pbp2X"
                     /locus_tag="ACL8JK_000672"
                     /gene_synonym="pbpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HGS1785602.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(6118..6435)
                     /gene="ftsL"
                     /locus_tag="ACL8JK_000673"
     CDS             complement(6118..6435)
                     /gene="ftsL"
                     /locus_tag="ACL8JK_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGS1785603.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(6447..7397)
                     /gene="rsmH"
                     /locus_tag="ACL8JK_000674"
     CDS             complement(6447..7397)
                     /gene="rsmH"
                     /locus_tag="ACL8JK_000674"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGS1785604.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            7563..7757
                     /locus_tag="ACL8JK_000675"
     CDS             7563..7757
                     /locus_tag="ACL8JK_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1785605.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            7773..8315
                     /locus_tag="ACL8JK_000676"
     CDS             7773..8315
                     /locus_tag="ACL8JK_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HGS1785606.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADRIGNQVFIVLFYLM
                     IFGNIIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            8326..8568
                     /locus_tag="ACL8JK_000677"
     CDS             8326..8568
                     /locus_tag="ACL8JK_000677"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785607.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            8579..8914
                     /locus_tag="ACL8JK_000678"
     CDS             8579..8914
                     /locus_tag="ACL8JK_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785608.1"
                     /translation="MKSLARLLIIHVFISIFLFFALTSGAISHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(9024..10025)
                     /locus_tag="ACL8JK_000679"
     CDS             complement(9024..10025)
                     /locus_tag="ACL8JK_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1785609.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(10085..11986)
                     /locus_tag="ACL8JK_000680"
     CDS             complement(10085..11986)
                     /locus_tag="ACL8JK_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HGS1785610.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMESCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYHFFADKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPRSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSKDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(12008..12301)
                     /gene="yajC"
                     /locus_tag="ACL8JK_000681"
     CDS             complement(12008..12301)
                     /gene="yajC"
                     /locus_tag="ACL8JK_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGS1785611.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(12301..13119)
                     /locus_tag="ACL8JK_000682"
     CDS             complement(12301..13119)
                     /locus_tag="ACL8JK_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS1785612.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(13106..13885)
                     /locus_tag="ACL8JK_000683"
     CDS             complement(13106..13885)
                     /locus_tag="ACL8JK_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS1785613.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(13900..14391)
                     /locus_tag="ACL8JK_000684"
     CDS             complement(13900..14391)
                     /locus_tag="ACL8JK_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1785614.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(14402..15592)
                     /locus_tag="ACL8JK_000685"
     CDS             complement(14402..15592)
                     /locus_tag="ACL8JK_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGS1785615.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGETREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(15604..16038)
                     /locus_tag="ACL8JK_000686"
     CDS             complement(15604..16038)
                     /locus_tag="ACL8JK_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1785616.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            16309..17124
                     /locus_tag="ACL8JK_000687"
     CDS             16309..17124
                     /locus_tag="ACL8JK_000687"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGS1785617.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            17143..17784
                     /locus_tag="ACL8JK_000688"
     CDS             17143..17784
                     /locus_tag="ACL8JK_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HGS1785618.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            17815..18816
                     /locus_tag="ACL8JK_000689"
     CDS             17815..18816
                     /locus_tag="ACL8JK_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HGS1785619.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            18826..19455
                     /locus_tag="ACL8JK_000690"
     CDS             18826..19455
                     /locus_tag="ACL8JK_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HGS1785620.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(19599..19661)
                     /locus_tag="ACL8JK_000691"
                     /pseudo
     CDS             complement(19599..19661)
                     /locus_tag="ACL8JK_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596946.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(19843..20219)
                     /gene="tnpA"
                     /locus_tag="ACL8JK_000692"
                     /pseudo
     CDS             complement(19843..20219)
                     /gene="tnpA"
                     /locus_tag="ACL8JK_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002458050.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(20599..23799)
                     /locus_tag="ACL8JK_000693"
     CDS             complement(20599..23799)
                     /locus_tag="ACL8JK_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HGS1785621.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTIGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAALHRMVPIEAKKKYKLRFKIKTDNKIGIAKVRIIEESGKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     LHKYVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVEQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKSPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKHGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            24022..24498
                     /locus_tag="ACL8JK_000694"
     CDS             24022..24498
                     /locus_tag="ACL8JK_000694"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGS1785622.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLQDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            complement(24720..26933)
                     /locus_tag="ACL8JK_000695"
     CDS             complement(24720..26933)
                     /locus_tag="ACL8JK_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HGS1785623.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVQTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(27335..27511)
                     /locus_tag="ACL8JK_000696"
     CDS             complement(27335..27511)
                     /locus_tag="ACL8JK_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785624.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            complement(27890..29236)
                     /gene="celB"
                     /locus_tag="ACL8JK_000697"
     CDS             complement(27890..29236)
                     /gene="celB"
                     /locus_tag="ACL8JK_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HGS1785625.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            complement(29316..29822)
                     /locus_tag="ACL8JK_000698"
     CDS             complement(29316..29822)
                     /locus_tag="ACL8JK_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785626.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LSQFISPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            complement(29853..30167)
                     /locus_tag="ACL8JK_000699"
     CDS             complement(29853..30167)
                     /locus_tag="ACL8JK_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HGS1785627.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            complement(30177..32156)
                     /locus_tag="ACL8JK_000700"
     CDS             complement(30177..32156)
                     /locus_tag="ACL8JK_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS1785628.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLLKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQSFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            complement(32274..32588)
                     /locus_tag="ACL8JK_000701"
     CDS             complement(32274..32588)
                     /locus_tag="ACL8JK_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HGS1785629.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            complement(32718..32957)
                     /locus_tag="ACL8JK_000702"
     CDS             complement(32718..32957)
                     /locus_tag="ACL8JK_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET transporter"
                     /protein_id="HGS1785630.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            complement(33009..34445)
                     /locus_tag="ACL8JK_000703"
     CDS             complement(33009..34445)
                     /locus_tag="ACL8JK_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGS1785631.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSLAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWKWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMIHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            complement(34635..34973)
                     /locus_tag="ACL8JK_000704"
     CDS             complement(34635..34973)
                     /locus_tag="ACL8JK_000704"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HGS1785632.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQEALDEHHQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            complement(35129..35338)
                     /locus_tag="ACL8JK_000705"
                     /pseudo
     CDS             complement(35129..35338)
                     /locus_tag="ACL8JK_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(35687..36079)
                     /gene="rpsI"
                     /locus_tag="ACL8JK_000706"
     CDS             complement(35687..36079)
                     /gene="rpsI"
                     /locus_tag="ACL8JK_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGS1785633.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(36098..36544)
                     /gene="rplM"
                     /locus_tag="ACL8JK_000707"
     CDS             complement(36098..36544)
                     /gene="rplM"
                     /locus_tag="ACL8JK_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGS1785634.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVVNAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            36901..37218
                     /locus_tag="ACL8JK_000708"
     CDS             36901..37218
                     /locus_tag="ACL8JK_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGS1785635.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(37263..38075)
                     /gene="folB"
                     /locus_tag="ACL8JK_000709"
     CDS             complement(37263..38075)
                     /gene="folB"
                     /locus_tag="ACL8JK_000709"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HGS1785636.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIEKMRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(38118..38672)
                     /gene="folE"
                     /locus_tag="ACL8JK_000710"
     CDS             complement(38118..38672)
                     /gene="folE"
                     /locus_tag="ACL8JK_000710"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HGS1785637.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(38653..39975)
                     /locus_tag="ACL8JK_000711"
     CDS             complement(38653..39975)
                     /locus_tag="ACL8JK_000711"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGS1785638.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFNSPYLIHYTDQISINGESISEARLEALMADY
                     QSLMGGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(39977..40951)
                     /gene="folP"
                     /locus_tag="ACL8JK_000712"
     CDS             complement(39977..40951)
                     /gene="folP"
                     /locus_tag="ACL8JK_000712"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HGS1785639.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFNQTFTVEELADFEILPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRNLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(41046..41753)
                     /locus_tag="ACL8JK_000713"
     CDS             complement(41046..41753)
                     /locus_tag="ACL8JK_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS1785640.1"
                     /translation="MKEKNMWKELLNRAGWIMVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIIGARKTQLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(41806..43224)
                     /locus_tag="ACL8JK_000714"
     CDS             complement(41806..43224)
                     /locus_tag="ACL8JK_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGS1785641.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            43414..44226
                     /locus_tag="ACL8JK_000715"
     CDS             43414..44226
                     /locus_tag="ACL8JK_000715"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS1785642.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKSFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            44565..45584
                     /gene="adhP"
                     /locus_tag="ACL8JK_000716"
     CDS             44565..45584
                     /gene="adhP"
                     /locus_tag="ACL8JK_000716"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HGS1785643.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            45817..46806
                     /locus_tag="ACL8JK_000717"
     CDS             45817..46806
                     /locus_tag="ACL8JK_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1785644.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            46834..47637
                     /locus_tag="ACL8JK_000718"
     CDS             46834..47637
                     /locus_tag="ACL8JK_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGS1785645.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            47661..48572
                     /locus_tag="ACL8JK_000719"
     CDS             47661..48572
                     /locus_tag="ACL8JK_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS1785646.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(48628..49962)
                     /gene="pepC"
                     /locus_tag="ACL8JK_000720"
     CDS             complement(48628..49962)
                     /gene="pepC"
                     /locus_tag="ACL8JK_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HGS1785647.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
BASE COUNT        14953 a        10903 c         8785 g        15423 t
ORIGIN      
        1 tcaaggactg gttttgatat agcacgttta agtaccgact tctgagctac tatagtagat
       61 tgaaactaga ataatacact tctactatac gacatgcccg tcgtacctca aaaggaacca
      121 gtttttttca gctggctcct tcttttttat cctcaaaatt ctatcttagg ctttctcacg
      181 aataaccaaa acgccatctt ccatatctgc ttccagatgt ttagcatcta aatgatccaa
      241 gtggaagtct gtcaccttat cacgaatttc ttgttcaacc actcgacgga gaggacgaac
      301 tcccatgact tcgtcgtaac cttcttctgt gatataatct ttagccgctt gactgactac
      361 caagtcaatg tctttcttag ccaaggtttg gttaacttca gccaacatca aatctacaat
      421 cttagaaagg tcttccttag tcaagtgtga gaattcgatg actgcattaa agcggttgag
      481 gaattctgga cggaagaagg gtttcaaacg gtccatcaat tctggtttat ccgcatcttc
      541 tgtcaagttg gcttcatagc caaatccagc atttgaggtc gcaataatga cagtgttctt
      601 gaagtttact gtatttcctt gaccatctgt caaacgacca tcatctagaa cttggaggag
      661 aagggtaata acttgagggt cagccttttc aatttcatcc aagagaatga tagagtatgg
      721 attgcgacga acacgttctg ttaaggtatt gctattgtca tcataaccca catagcctgc
      781 tgttgtacca attagcttag aaacagctgt gcggtcactg tattcagaca tatccaaacg
      841 gataatcgca tcctgggttc caaacatatc gagtgccaat tgcttagcaa gctccgtctt
      901 accaacccca gtagacccta caaagaggaa gctgccgatt gggcgatttc cttcatcaaa
      961 accagcacgg ttacgacgga tagcacgagc tacagcttct acggccttat cttgaccaat
     1021 caccttgtct tgcaagcgat gagccatatc tttcaaacgt tcgatatctg aagctcccat
     1081 ttgcgatact gggatacctg tcattcgttc cacagattca gccacatcgt tgacacttgc
     1141 agtcactttc atatcttctg tgtggttttc gattttcttt tccaattctg caatgcgtgt
     1201 tttatagttt agagctgctt caaaatcttc tgcttcaact gctttttctt gcttgtcttt
     1261 ttccgtttcg atttctcgtt caacagcatg cacatctgtt actggatgtt gagccgccaa
     1321 gtgagcagcc gttacatcga caaggtcaat agccttatct ggcaagctac gttgaggaat
     1381 gtattgaaca gaataatcca ccgctgcttt caagacttcg tctggcaaga tgacattgtg
     1441 gtgttgttga tagaggtcac gaatggcttg aagaatttta aaagtattct ctgctgaagg
     1501 agcattgacc ttcacttcgt tgaaacgacg agcaagagca gcattcttca agatggtgtt
     1561 acggtattcg tcttgagttg ttgccccaat cactgtcaat tctccacgag agagagctgg
     1621 cttgagaata tccgcaagtc ctttagaacc actgtctcca ccagtgctac cagcaccaag
     1681 aatttggtga atttcatcaa agaagaggat aatattccct gcttctttca cttcattgac
     1741 taagttttgg acattttctt caaagctacc acggtattga gtaccagcct caagacctga
     1801 gatatcaata gaaataattt ccttgttctt gatagcagca ggaacatctc cgttcacaat
     1861 ggcttgcgct agaccttcga caactgctgt cttaccaaca cctgcatctc cgaccaaaac
     1921 aggattgttc ttggtgcgac gtgagaggat ttcagatgtt tcttgaattt ccttgtttcg
     1981 tccgataaca ggatccaact tgccctcacg cgcttctgct gccaagtttc gacctagttt
     2041 tgcaaggaca ccgtcttgtt tcatacctga tgcctgttgt ggcatttgca catcagtttc
     2101 tgcatttcct ggtaattgac cagtcgcacg atagtgagca aattcctcag gtgtgacttc
     2161 gcgtccatta attaagtaac ggcgattttc agaactatat cctcgcatac cacccatcaa
     2221 ttggttaaat aaatcatcca tgttattaaa attattaaag ttgttattca tattctttac
     2281 ctctttttgt ttacttagtt atgactactg atattgacta tctttgacca ttgttttaaa
     2341 aaatttagac tagctaaacc gctaccctac gtactatttc tggtttttct ttttcaagca
     2401 ggagtagact atctttactt ctgaaaattt ctagatgaaa catagaccca cctctttcta
     2461 ttttacttta aataagtgtt ctagtaaggc tttcatttac cttacgttca taatatacta
     2521 cattggtcag aaaaggtcaa gagttttgac tttaactgac caatattttt ttacactctt
     2581 cgaaaacctc ttcaaaccac atcagcttct ccttatctac aacctcaaaa ccatgttttg
     2641 agctgacttc gtcagttcta tcaaccatct caaaactata tattaaaatg aaataagaac
     2701 aggacaaatc gatcaggaca gtcaaatcga tttctaacaa tattttagaa gcagatgtgt
     2761 actattctag tttcaatcta ctatattttg agcagcctaa agttagcttt ctagtttgtt
     2821 ctttgatttt cattgtgtat ttaaatacaa aaacaccctg aaacatcagg gtgccattct
     2881 tacattaaat acaaaattgc tagggtcagg agacttgcta gaagtcccac tccccaaaag
     2941 aagaagtcaa ccttccactc gctccaagga tttcctttac cagacaatcc cccaagctca
     3001 aaatggtgat gtacaggcgt catacggaaa atacgtttac cacctgtcag tttgaaataa
     3061 ctgacttgca tcataacaga agttgtttca aaaacatata caattccgat aatcaagaga
     3121 gtccattctt ggtggagagc catagagata gctgccagca tcccacctag ggccaaactt
     3181 cccacatcac ccataaagac cttggcaggc ttatggttaa agatgaagaa accgagcaaa
     3241 ccaccaatca tggcaagaat cactagaaga atatccatct gaccttgcac ataggcaata
     3301 actccatagg cagacaaact aatcacaacg gaaatactag ctaaaccgtc aacaccgtct
     3361 gtcaagttta ctgcgtttga aaaaccgact agccagaaaa gagcgaagaa aatatagaaa
     3421 aatcccaaat gaactggata accaaagaca gacaggatat cgccaccgcg ctcatagaaa
     3481 agatagaaga taactccacc tagaagctga agagctaatt tttgcttagg attaagcccc
     3541 tcattgattt tacgaaagac cttgagaaag tcatctaaaa atccgaccaa gccatacaag
     3601 accaagatga acaaaatcat tcccacatta ttgctgaatt ggctactaaa tagggcgaaa
     3661 aagaaagcaa ccaaaacaga agtaatcaag aaaaccaaac ctcccattgt aggagtccca
     3721 gcttttgcct gatgctgttt gacatcctca tgcatctgct ggcctgtaat ttgcgccttt
     3781 ctataaaatt ggataaaggc cggaatttct actaaagtta gtaaaaatgt cacaattcca
     3841 gcactgatgg aaataaacat attagtctcc taaagttaat gtaatttttt taatgtcctt
     3901 gatagctgtg ttagcacgaa catcttgctt ctgcacagta gagcccgaac cttgaaattc
     3961 aagttctata ttgagccact tagcaagggt ctcagcagtc tcctttgtcc aaccatacat
     4021 atctggaacc tcctctgctt tatcagataa gataaggact tgctggttcg gggcaagatt
     4081 cttcccttct tcagcagaac tgtttttaat cttcgttcct gttcccacaa cgatgggttg
     4141 tacaagattg cgacgcaatt cttctgctaa atcaccaggt gaaatatcct tgacactagg
     4201 cataggataa ggactttgtt gacttacttg ctctaaagcc ttagctgttg tttgaagatt
     4261 gagagagtct ttcatagctg aagcccgctc caagatagga ttggcaaatt ctcccaactg
     4321 aatacctgaa taatgttcag gttgttggac cgtcacatac aagataaaat caggattttc
     4381 agccggactc atcgatacag ccgagaaaat atagtcggtt aacccgacta gataaccacc
     4441 atttttctcg tcagcaatct gagccgtacc agacttgagg gctacatttt gcccaggaac
     4501 agttacagtt ggcttgcctg tgctgtggtt atacatggtt ccataaaccg gatccgtccc
     4561 taccaaaacc atgttagtcc gagttagact agctgcatct ttagaaacag gatttcccac
     4621 aatttctttt tgagatttcc gagcagtttg atcatttgga tcataaatgg cactaataaa
     4681 tttaggctcc agcatgacac cgtcattagc aatagctgta aaggcacgaa tcatttgcgt
     4741 ctgggtcact gaaatccctt gtccaaatga gctttgcgca atgttgacaa tattatccgc
     4801 aggaagctga ccagcatact catccgtcaa accgaaacgg gtcggaactc caaatttaaa
     4861 acgattaaga taatcaagcc aggtagcatc tcccatcttt tgctcaagga gagtcatccc
     4921 aacgttactt gagtgtgcaa aaccttgaga aaaagtcatc attctgccac cagtcaatcc
     4981 ttcattaacg tcccaatctc gaatcgtggc atctgcaatt tttaactcac tactattaaa
     5041 gacttctcct cctggaaagg tattattatc aatagcagca gccaacatca tcactttcat
     5101 agtggaacct ggctcatagt tactttggta aaggatatca cgccaaacaa agtcctctgt
     5161 aatgccttct tttgtatctg catcaaaggt cggtcgttgc gttgttgcca gaatttcccc
     5221 tgttttagca ctgaccaaag tcgctgtcat gtactttcct tttaccttct cttgaaaagc
     5281 atccatctgg gtttccataa aggactggag ggggctggaa atggttgtat aaacatcctt
     5341 accgtccatc gttcgttggg aaacttgttc tgttccgggt acaatattac ccagacgatc
     5401 cttttcatag gtaataatgc cgtctgtccc tgcaagaata ctgttcaagg aactctccat
     5461 tccagaggtt cccagcaagc tcttgcttcc atcttcattt tcatggagct gagctaggcc
     5521 gataaaacta gaagcaaatt gtccgtttgg gtaactacga ttgggactgg ttgtaaaatc
     5581 aatccccttg acctctgcag cttccaattc ttttttgata gacatcatat tggcataggt
     5641 aatcccattt ccctttgctc caaaggaaac ttgcttgaga ttaggttgcg agagttgctc
     5701 tcttacatag gattcttcca tgtccagata cttatgaaag acctctgcaa ccttgttaaa
     5761 ttgtgttttt tctacgtaaa gaatcttacc cgttgctgac ttatagttct catcaatgac
     5821 cgcatagaca ttataggagg ttgcatcctc agcaatcggg actccatttc ggtcataaat
     5881 agtcccacgt ttggcaggaa ctgtacgggt ggtttgatga accttcttag cttccttcgc
     5941 taaatctgtt ccaaagcgag tgcctgtccc aataatgacc gcaaaattga ctaaaaaaat
     6001 ggcaaaaaca aagacagata ataaactcag actttttcca actctgcgtc tgttttcagc
     6061 cggcgatttc cgatttttgg tcgcataacg gattactctt tttgtccact tcatatctta
     6121 ctccgctatt ctaatatttt cattgtttaa ttgcaaatcg tgtgaattgg caatttcttt
     6181 caaacgttct gcacgtaata gttcattgac ctcttgcttg gcatcgtcca attcggtctt
     6241 cttttcctct atctgcgcat tgatttttgt caaatcattc tgcacttgca agagcttggt
     6301 ctgcataaaa ataatactaa tggctacaat aagagtggtt acagcaatgg aaaagtaaaa
     6361 agctttttcc acacgcgaaa accgtttaag ttgcatctgt agtatttgac ctgttttttc
     6421 cattttttct gccatctttt tccctcttac ttgtgaattt ttctggccac gcgcaacttg
     6481 gctgagtgcg agcggttatt ggcttctaac tcttccgcac ttggcaagat tggcttacgg
     6541 gacaccaatt ccatcttggg cttgagatca tctgggatga aaggcaagcc ttttggaact
     6601 tcaactgttg aagcttcctt gaacaattgc ttggtcaagc ggtcttctaa ggaatgaaag
     6661 gtaatcactg aaattctacc atccagagcc aacatatcca tagcctgctg gatggactca
     6721 tctgccgccc ccagttcatc attgacttca attcgaatag cctggaaaat ctgcttagca
     6781 ggatgcccct tcttcttgag ttccttggca ggtttgacca acttgataat ctctgctaac
     6841 tcagtcgttg tctcaatcgg cttcacttca cgcgcttgct caatcttacg cgcaatctgt
     6901 ttagagaatt tgtcctctcc atacttgaag aaaatacgaa ccaagtcatg atagtcataa
     6961 ttgttcacca cttcatacgc tgtcagacta gcatcctgat tcatccgcat gtccagtggc
     7021 gcatcctttt tataagaaaa accacgctca cgctggtcta attgaggact agacactccc
     7081 aagtcataac aaattccatc aatttcctga acaccagctt cgcgcaaacg tgcctgtaaa
     7141 tgacggaagt tgtccttgat aaaggtcacc attcccttct caatgtaagg tgccaagcgt
     7201 ttttgcgcat tgtcaatggc attctgatcc tggtcaaagg catagagatg gcctttttca
     7261 cttaatttac ttaataaata ctcgctatgg cctgctccac ccaaagtcgc atcaacgtag
     7321 ataccgtcag gttttacgtc aagcatatca atcgtttcgt ggagtaagac cgttacatga
     7381 tgaaattctt ttgtcatatc ttatctattt taccacaaat ccgaccagct tgcacttgtc
     7441 agacaaatag gacaaggaga ctactatttc ttcaaaaaat atgtcaaaaa tacttgacac
     7501 tttatgttta aaagactata atatagtcaa atatatacga cataaatcag aaaggagacc
     7561 agatgaatcg tgtgaaagaa tttcgcaagg aattgggtat ttcccagctc gaactcgcca
     7621 aggatatcgg tgtctcgaga cagactatca atatgattga aaacgacaag tacaatccaa
     7681 ccttggaact ctgtctcaat ctcgcccgca gcctccaaac tgacctcaac agtctctttt
     7741 gggaggaaga tttttaaaaa aggagcaaac tcatgaaaaa agaaaccttc actgaaaaac
     7801 tgatcaaacg cacatacggt atttctggtc cccttgacga atacaaacgg cgtgaggccg
     7861 atcgtattgg gaaccaagtc tttatcgtcc tcttttatct gatgattttc ggaaatatta
     7921 ttccactcct tctggcctat aaataccctc aagaagtggc tctaatctat cctcctctga
     7981 ttttagtgat tgccctcatc gcttctggct atgtcaccta ccaaatgaaa aaaacaggca
     8041 tcacagtcat tgaaccagat atgctgaatg agaaagaaag caagcaacta cactaccctg
     8101 gtctgaaagc aggtttgttc tttggtctat ggatgttttt tataactcct cttctcagta
     8161 tactcataga tgaaggtcag gactattttc attctcttct cactataaga aatggtgtat
     8221 caagtattct cggttctatt ttcttcggag cgagcataca gttcctcatc tcccgtcgca
     8281 ttgcaaaaac taagaaaaat caagatgagg attaggagga aactcatgaa aaaagaaaag
     8341 aaacagttac gttatcctgg tctgaaagca ggttcgattt atggaacagt gatatttttt
     8401 ataattccac tcattgatac cctaacaagt gaaaatccaa attttatcag ttctcttcta
     8461 aatacaaaac atatttttaa aactatactg ggagctttct ttttcggagt gatgatacat
     8521 attgtcgact cacttcgtat tgcaagagct aaaaaagacc aggattagga ggtgccttat
     8581 gaaatcacta gctagactac tgatcattca tgtttttatc agtattttcc ttttcttcgc
     8641 ccttacttca ggagctattt ctcatacagt tttactactc ctactcctct ttcttcctgc
     8701 gctcaataaa ggacttgaga aaatacaatc aaaacggata cctgtcctca acgcagccct
     8761 cttctttctc ctcatatcct ttccacaact tttaaccaac cctgtccaat ggaaattttc
     8821 aatattccta gtcgtaacca tcatttcaag tttggcctac ttctataact tttatcaagt
     8881 agttaaagaa gtagatcaaa aacagttgat ttaggagctt gctcccataa tttctcattt
     8941 tataggcaaa taatcccacc tagcttgttc taggtgggat tattttattt cttaacagag
     9001 attgcaagtc attttccttc attttagaaa gtcgactctt tccaattcac actacaatcc
     9061 aagacttgtt gcctttcttc ttgattgcga ccttcaatct ggtcaatcaa aatctttgta
     9121 gcctgttgtc cttcctcaaa ggagggctga accagcgtcg aaacacttgg agaagaaaag
     9181 caagtccact ccgtattgtc aaaaccaatc aacccaactt gtggcaagtt ataattcaac
     9241 tctttgataa cggtaaagac tagaggtagg gcccaacagt tagggataaa taccagagtt
     9301 ttttcatcgg gatcgatttc tttttgtaaa aattccttaa tttgttccaa attcgtatgc
     9361 ttatcttcaa tggttagact ggcgtggcgc atattagcat ctgttaaagc atccacaaaa
     9421 ccacttgccc gctcaatccg agtactcaaa cgactcgtat ccgctgtaat caagagaaaa
     9481 tgctcataac ctttttcgat acaggactgg gtcatgtcat aaacggcatc atagttattg
     9541 gttttaaccc agctagtccg gtgttcatag agctgactat caaaaaagac cattttcttc
     9601 tttttctcat cgatgatacg agaatatttt cggaaattag aggtcggctg aataataaag
     9661 ccgtctactc ccaagagaag catgctttca atataccggt cctcactctc ttggctgtaa
     9721 ttactatttc ctatcattac ctggtagcca ttctggctgg cgatatcctc aattccctta
     9781 acaatttggt ttgagaaact gttggtaata tcaccgatca aaacaccgat taattttgtt
     9841 cgtttggagt ttaagctacg cgcaacaatg ctcggtttgt aatttgtttc atgaataact
     9901 ttttcaatct tttcacgtgt ctcttgggac attttttcat atttcccgtt taggtaaaat
     9961 gacacggttg ttttcgaggt ctgagccatt tccgcaatgt cttttatggt cagtttcttc
    10021 tccaatctaa aacacctcct actaatactt attataacat attcactatt caaaatgcct
    10081 atttctagca ctgcaagcga atcattctct catttatttt atcatatact agacattttc
    10141 cacgcatttt tgttccgtca acgaggcaca atttttcacc tacacaaata tccttgctta
    10201 ataacagaat cagcttgtct gtttcgtcat ttttcacttc aaaagccaga gcattttcca
    10261 cttcacgatc atctgtctgg tagacagaat gacggatgat ttcaaaactc tcatgcgcaa
    10321 tgatggtata atccagcatc tgattctcaa agaattggcg cttggtgagt ttgctacttc
    10381 tttcaagctc attgtattta ggagaaatga tggtatcttc caaatcaaaa tcaacttcac
    10441 tccatagtct caactgattg attttcccat cttgataggt cacatccttg tcaaggataa
    10501 actgagtcaa cgcctcatgc tgaccttgac acctgatgtc atctaccaag agccagacat
    10561 cctctaccaa catgaggatt tttctcttgt gaagataagg caaatcaggt tctgctgacc
    10621 aataagcccc ttcaatataa tgcactccct ccctttcttt atggtgacaa aacagggagt
    10681 gaggatagta ttcatattcc caggatcccg tgattctttc cggagctttc ccatctacaa
    10741 tgcaggtcga atgactccaa gcactcttta agagataacg ttcatatatc tcccgataag
    10801 aataacgccc agcatctatg aaaataggtt ggccttgata ctgtaagcaa aaactattct
    10861 cgtcactatg gctatgggca cttcctagcg gaccattttt gaaaaataga taacgatgtt
    10921 catccttaat gcagacatgt ccagagtctt caaagatcat ggacctaggc tgccaagctc
    10981 tcttttcaaa ttcctgcagt cgcttgacct tttctcgccc caggaacaag aggctaagca
    11041 aatcgacttt aacatccaga ccgttaagaa ggtcttcctt gttcaaaacc acagcagaca
    11101 ggctcaacat ttctgtcgtt tctgtagaat cgctatcacc aaaagccaaa gttcgtccat
    11161 ctaagcctgt catcatttga atataggtcg ccatcttttc cagcaactct tggtaactat
    11221 cttgcaagtc tggaagcaag agacacaaat ccagcaaggc tttataaacc tctacatgat
    11281 agagaatcga ctgttcaaac tggcttccat ctcctaaaat ctgtgtctca atttgctgtt
    11341 tcaactcctc tgaagcaaaa tggtaagctt cttctaggtc catcttatct gcaaagaaat
    11401 gatagatagc aagcatcgga attgtttgta aaattcccca gttactaagg gtgtacttgg
    11461 cgcgatagtg gcttttcata aagtcaatct gcttttctag actgaccaaa attttctcta
    11521 gttctttctc ctctagcaag tcaaatttca agaggagcaa gagtagtttc aaccaagtaa
    11581 aggaacgaat acccgtatcc aaggttctag tcatcaagga ttgaggagaa aattctctca
    11641 cctgctcaat ccaatcaaat agaaagaact tgcacttttg aatatagtcc ttatctcctt
    11701 ctaccagata ccctatcata aactgcaaga gatattcttg tcgattgagc atataagacc
    11761 attctggatc atcttcaaat acttgatccc ataccatcgg ctggatttga tggatttttg
    11821 aacaagactc catatcccaa ggactatcaa acataaaacg attgtccatc aagcgttcaa
    11881 gggaactctt gactttctca tagtcttttg aacagtggga caagatataa tcacgacatt
    11941 ggtttccatc gactctttca aaaaattgtc ttctttcttc tttcattatc tattaccaga
    12001 aaaagaacta cttaaaaagc agttcttttg tctttcccat tacactttcc ttttctacat
    12061 agatgaccac accttttgca atctgcaagg agaccaagtc atctttgata gaaatgattt
    12121 ttccatgaat tccagacaat aacaacactt catcaccaga tgttaaagaa gctaaatact
    12181 cttgtcgttg ctccatctgt ttgcgaagca acttttgctg acgaatagaa tgaaagcttg
    12241 acagtaaaag gggactcact gccaagacaa tcactattcc ataaaacaat gttgtatcca
    12301 ttaagctata atcttaagcc agcttccgat aattccgatg ataactgtta aaataacgag
    12361 tttatatgtt gtccatttct tttctttgat caagtagtaa actaaaagtg taaatagggc
    12421 tggtagaaga gctggagcaa ccttatcaag cattccctga atacttacga tactttgttt
    12481 agcgtctgct ttaacttccc ctgcagcaaa ggtaatcggc accataatct taacagatgt
    12541 cgctgccaaa ccagcaatta cggttacacc gataatattg gcaatacgag aaatcgttgc
    12601 catctgctcg cttagtttat caatcacagt tgttcctagt ttgtatccat acagaccagt
    12661 tgacaattta atcgctgtta aaatcgtatt catcgcaagg aagaacaaga ttggaccgac
    12721 aaccaagcct tcttgagcaa acgaagctgc gatggttgag aacaatggag ctaaacagaa
    12781 ttgagaaaga gaatccccaa tacctgccaa tggtcccatc aaggccatct tgatgctacg
    12841 tgtttctttt gttggtcgac cattttccaa cattacaaga tgcaagctgg taataaaagg
    12901 caggaagtgt gggttggtat tatagaattc acagttttct tccaaggctt ggtagaaacc
    12961 ttcctgatcc tctccatagt gttttttcaa agcaggatac atcacattgg catatcccaa
    13021 cccttgatag ttactatagt taaatccatt ttgacaaaag aatgcccgca aagacgtttt
    13081 aagataatca cgttttgtta atttgttaga tccagtcatc gtgtgcttcc tcctctacca
    13141 catgatccgc tgtttttggc ttgttataaa attcaatcaa agcaaagata gtacctacaa
    13201 ttgcaatacc aattgttggg atgtttagat aagctgcaca aacatatccc aacaagacaa
    13261 agggaatcaa ctctttctta gccatcactg acaagatcat cgcaaaaccg atagctggga
    13321 gcattttacc agcaactgtc aaacctgtaa gtaataccgg tggaatgtag tctacgagtt
    13381 tcaacaaggt atccattgaa agggcaccca agcaacccaa ggtaaatcca ataaaggcaa
    13441 acaaccaaat tgttgcattt agagtgaact tgaatttctt caaattatgg tttttcaagt
    13501 gcttcatcgc cgtttcaggc gcaccagcac gtacagtgta ggcgaaagtt tgtaagaatt
    13561 gaatcgccac agcaatcgga gtagagaggg caagagccgc ttctggactg actttaccag
    13621 cactagtgat agccatcaag gtaccaaaga taccaggtcc gattgggttt ggtggaacag
    13681 tacctccagc accaacaccg aatcccatat aagccaattc accaatagct cccattgcaa
    13741 gagcagtagg cagatcacct agaataattc cgacaccaaa tgacagaaca atacatctat
    13801 tggtgtaaat tcctaacagc attccactaa aacagaaagc tgtccataat ccaattaaaa
    13861 tcgcttgaaa tacattaatc gacataacga tctcctcttt taaatatagt ccataatgtt
    13921 gacttgaaca gctccatcat ttcctgttgg agttgttttc gtattaaatg ttacttgatg
    13981 agtttggctt aattccttga gggctgcctt gtcctcttca cccaggaaga tggagcgtgt
    14041 cacttgctct ttaccagggg cattgtgaat gttcccaata ttgatttctt tgatagggac
    14101 accaccttct accaaggtta aagcgtcctt tacatccttt acaacgataa agatcgtttg
    14161 agcaggatta gccttgtgaa tgatatcaat caccttttgc aaagggaaga aacgcatggc
    14221 aactgagtct ggcacaactg ttttcatcag agtttgttgc atcttgtccg tgcttacttc
    14281 gtcattggca acaatgaccg tattacaacc taggtatttt acccaaagtt gtccttgtcc
    14341 atgaatcaac cgttcatcga tacgggtcat aataatattt ggcattgtca tatttctcct
    14401 cctaccaata taggttccag tctttgtaga aacggataag ggcttctagg taatagtagt
    14461 caccccagat attgccttca tccactcctt tacctgaatg ccatgagtac acaccgtgga
    14521 ggagacttgt cccaccaggg gtaaattgat catttgcata atgttcgatc aaggaacgaa
    14581 gcatggcatg catagcatgt ttataaatat ctttgtcagc atccacctct gggagatgtt
    14641 ttagcatttc atgaatccca cagacggcga tagctgttgc tgaagaatct cgtgattgat
    14701 cactaccatc attaaaaatc aaatcccaat aggacacatg atcttttggc agacgattca
    14761 agaaataatt ggtcacaccc ttaaacaagt caaagcagga ctcgtctttt aagtgacgat
    14821 aagtcaaagg aataccatag actccccatg attgaccacg tgcccagcat gaatcatcac
    14881 tatacccttg tctcgttaca cctttaaagg gttgacctgt ctcaggatca aaatagaagg
    14941 tgtggaagga cgaagcgtca tcacggatta cattattagc tgaagcatag aaatggcttt
    15001 ctgcaatatc gtagtatttt tgatcgcctg tttcttgata agcaaagaat aagagttgga
    15061 tattgagcaa gcagtcgata atcaaacggt aatgctcttt cttgcccaag tctccccaag
    15121 cttgaataaa accacctttt tcttgatagc gttcaatcaa cttatctgca gctttcaagg
    15181 ttgcttctct agtctctcca tctccattta tcttatattc agccatacaa gacggtgtgt
    15241 acaagaagcc gagatcatga tgatccaatt ctactctctt attgacacga tccaggaaag
    15301 aaagaacatt tttatgagcg atgtttttaa atgcatcctg ttgactgtat tcataagcca
    15361 accacagttc tcctgtccag aaaccattgg tccattccgt gttatccatg attggataga
    15421 cattatcaaa ggtagctggc gtcgggaaat cttccttgaa atagtcaagg ttgagttcta
    15481 actgccgaat aaccttatcg attgcctggc cgacttcttc tttcgtcaga agtggtactt
    15541 ctaagaagcg ctcaggcgac tttatttttt caatcgtaac cttttttatc attctttcac
    15601 cctttaaata cccgattcga aatcttcttc ctcttcctct gcatccgttg aaaacaattc
    15661 tttaccattt acgactccgc cctgggccgc cactactgat ttattaacaa cctcatcaaa
    15721 gctatgagcc attctagcaa agactgcttc cattaacatg gctaagttca aacccgagag
    15781 aacattcatt gttttggctg gattttctcc cattatggta gaagaaacct tgaatggcga
    15841 tcctcccaag agatcactta ggattaaaac ttcttcttca tttgaaattg caagtaagat
    15901 tttttgcttg agttcatctg ctgacattcc ttccacaaag tcaatcgcct ccacattttc
    15961 ttgattgcct gcaatcaatt gtaaagaact ataaatccct gtagcaaaat gtccatgccc
    16021 tacaagtaca attttcatct tttctccttt cttgtttagg tttaccggtt tactttatat
    16081 tccccattgt aatcctttat ttttatcttg tcaatagttt ttttaaaaaa atattagcgc
    16141 tttcattatc tttttaatca ttttaataga cagaaatttc aaaatattcc atttttaagg
    16201 aaaataaatc tttttataaa taaaaatatt tatttattga caaaaccggt ttactagaat
    16261 ataatttgat tatagagaag tcttaacaaa tttgaaagga agtatcaaat gacaaataca
    16321 tcattctcaa ttgagcagtt ttctttaaaa ggaaaaattg ctctcatcac cggcgcttct
    16381 tatggaattg gatttgctat tgccaaatcc tacgctgaag ccggcgctac tattgtcttt
    16441 aacgatatca atcaagatct ggtcaataaa gggattgaag cttatcgtga agttggcatc
    16501 gaagcccatg gatatgtctg tgacgtgaca gacgaggacg gtatccaagc catggtcaag
    16561 caaatcgaac aagaggttgg tgtcattgac atcctcgtta ataacgctgg tattatccgc
    16621 cgagttccaa tgtgcgaaat gagcgccgct gatttccgta aggtcatcga tattgactta
    16681 aacgcaccat ttatcgtttc aaaggcagtt attccttcta tgataaagaa agggcatgga
    16741 aagattatca atatttgttc gatgatgagc gaactgggac gtgaaacagt tagcgcttat
    16801 gctgctgcta aagggggctt gaaaatgttg acccgcaaca ttgcgtctga atacggtgga
    16861 gccaatatcc aatgtaacgg aattggaccg ggttatattg ccactcctca aacagcacct
    16921 cttcgtgagt tgcaagaaga tggttctcgc cacccatttg accagttcat cattgcaaaa
    16981 acacctgctg cacgttgggg aaatcctgaa gatttgatgg gccctgctgt ctttctcgct
    17041 agtgatgcca gcaattttgt caatggccac atcctatatg tagatggcgg tatcttagcc
    17101 tacatcggaa aacaacctga gtaaaaatag aaagaagatc ttatgaaaat cgcattaatc
    17161 aatgaaaata gtcaagctag caagaatcac attatttacg atagtctaaa agaagcgaca
    17221 gataaaaaag actaccaatt atttaactat ggtatgcgtg gagaagaagg agaaagtcaa
    17281 ttaacttatg tgcagaacgg actaatggct gccatccttt taaatacaaa ggcagttgac
    17341 tttgttgtta ccggctgtgg tacgggtgta ggggctatgc ttgctttaaa cagcttccct
    17401 ggtgttgtct gtggtctagc agtggaccca actgacgctt acctttattc tcaaatcaat
    17461 ggtggtaacg ccttgtctat cccttatgcc aaaggatttg gctggggggc agaactgacc
    17521 ctcaaattga tgtttgaacg cttatttgct gaagaaatgg gcggtggcta cccaagagaa
    17581 cgtgtaatcc ctgaacaacg caacgctcgt atcttaaacg aggtgaaaca aatcacccac
    17641 aatgatttga tgaccatcct taaaacaatc gaccaagact tcctcaaaga caccatctct
    17701 ggcaaatact tccaagaata cttctttgaa aactgccaag atgatgaagt cgctgcttat
    17761 ttgaaagaag tattagccaa gtaaagctat tctaaaccag aaaggaacta atggatgacg
    17821 aaaatattac tgtttggcga accattaatt cgaatctcac cattagatgc caccagtatc
    17881 ggcgatcatg ttgccagttc gacttatttt ggcggatcag aaattaacat cgcttgtaat
    17941 ttgcaagccc tgggtatctc aacgaaagtc tttaccgcac tccctgccaa cgagattgga
    18001 gatcgttttc tcacattctt gaaacagcac caaatcgata ccagttcaat ctgtcggctt
    18061 ggcgatcgaa tcggcctcta ctatttggag aacggctttg gttgtcgtca aagtgaagtt
    18121 ttctacgatc gtaagcatac gagtatcagc cagattcggc caaacatgct agatatggat
    18181 tctctctttc aggggattag ccattttcat tttagtggaa tcaccatagc tatcggtcaa
    18241 gaggtccgtg cgatccttct cctactcttg gaagaagcca agcgccgagg aattgtcgtt
    18301 tcaatggatc tcaatctgag aacaaagatg atttcagtcc tagaagccaa gtatgaattt
    18361 tctaagtttg cacgttttac tgactattgc ttcggtattg atcctctcat gattgatgac
    18421 caaaatctag agatgtttcc aagagacagt gctagcctag aagaggtgga aaatcgcatg
    18481 cgacttttaa aagaagccta tggtttcaag gccattttcc ataccctccg atctagtgat
    18541 gagcaagaca aaaatgtcta tcaagcctat gctctggaag aacgatttga agagtctgtc
    18601 caactaaaaa ctgcagtcta tcaacgaatt ggtagcgggg atgcctttat atctggtgcc
    18661 ctttaccaac tactccatca ttcctcccta aaaactacca ttgactttgc agttgcgagc
    18721 gcaactctca aatgcactct tccaggagac catctctcca cttccgcaac tagtattgaa
    18781 aatttactgg caaatgcaca agatatcatt cgttaggaga attacatgac caaatcagat
    18841 acgattattg aactaaaaaa acagaaaatt gtcgctgtca ttcgaggaaa tacaaaggaa
    18901 gaaggactac aagcctcgat tgcttgtatc aagggcggta tcaaagctat tgaaatcgcc
    18961 tataccaatc agtatgcagg acaaatcatc aaggaacttg tagacttgta tcaggacgat
    19021 cagagtgttt gtatcggtgc aggtactgtg cttgatgccg taactgctag agatgccatt
    19081 ctagctggag caaattacgt tgtttctcca tctttccatg ctgaaactgc gaaaatgtgc
    19141 aatctctaca gcacaccgta cattccaggc tgtattaccc tcacagagat cacgactgca
    19201 cttgaagccg gtagtgaaat catcaaactc ttcccaggta gtactctcag tccagcatat
    19261 atctctgcag tcaaggcacc gatcccacaa gtttccgtaa tggtaaccgg aggagtcggc
    19321 ctaaacaaca tccctcaatg gttcgctgct ggtgcagatg ccgttggaat tggtggcgaa
    19381 ctcaataaac tcgcttccca aggcaacttt gaccgcatca gcgagattgc ccaacagtat
    19441 gttacactca gataaaatca taactacccg tctaacgggt ggtttatctc agagctataa
    19501 gcccaaatca tcagccagcg cctaaagacg ctggctttca cgttgttcaa gccttattgc
    19561 tcttgactcg tcacttgcct ctttaagaga ctttggtatt acttaccact atccctaaag
    19621 ggatcctcat attcttttac actcaattta tctagtgcta tagtagattg aaactggaat
    19681 agtacacctc tacttctaaa acattgttaa aaatcgattt gactgtcctg atcgattttg
    19741 tcctgttctt atttcatttt actatatatc atactttact agttctcaaa ttttcatact
    19801 cgtgaagaaa tcatccactg gataatttct ttaatcttga ctatatttct taagtgtggc
    19861 tttattaagc cctactgtac ttacataata accttccgcc cagaaatgcc gattcccaaa
    19921 cttgtacttg agattggcgt gtttgtcaaa catcatgagt gcacttttgc cttttaaata
    19981 ccccataaaa cttgaaacac ttagccttag tggaatactg actaacatgt gtacatggtc
    20041 tggcattaag tgaccctcga taatttcaac acctttataa ctacacaagc gatgaaatat
    20101 ttcgcctaaa ctacttctat attgattata gatgactttt cgtctatact taggggtgaa
    20161 cacaatatga tagaacacat ccactttgtg tatgataaac tatgagtctt ttgtgccata
    20221 ttttttctcc tttcgcttta caattggatt gaacaccttt attgtatcgc gtttggagtt
    20281 tttttggtat aaccttcgac gcgcacccgt atagcgggtg gttgttttgt ctcgcacctc
    20341 acggagcgag acggactaat atagtggagt gaaataggat acgaacaaat tgattaggaa
    20401 aatcaaatga atttatagaa atcttttagc agttatgacg tcctattcta gtttcaaaac
    20461 gctatagtca cataatgaag taaaaaagga taagtatcaa cttatctttt ttaaaagaaa
    20521 aatccgaaga tatttggcct tcttcggatt ttttctattt tccacagttt catgtaattc
    20581 atctagatga tgaacaaatt agttgttctt tcctctacgg aatagataaa acgccccaag
    20641 tagcaagaac cctagacttg ccaagattga ctgaccttct cctgtctgag ggagattctt
    20701 ttgatccgaa tggttctttt cctcttcaga tttttccttt tcttttgaat tctgtacttg
    20761 tggctgagct gcttgctcta gctttttaaa gacttcctga tctggagctg attcctgggt
    20821 ttcaggatta tagtaggcaa tcttatattc atccccctct tttcgaatag tatagactcc
    20881 acgtttcaaa acttggaatt ggttggaaat agtagagaca gaatcatcat atttcacaat
    20941 gccccaaact ccttgtttag catcataaac agactgaagg gtttcgttat tttcgatgag
    21001 gctactttct aactctttta tcatttgatt gaaggtggca cgatccacgt tagggataag
    21061 catatagcca taagaatctc cattttgctt atgagcctga ctaatcgtaa gaaattcatt
    21121 ttcaacttcc ttgtctgact gtccttcatt gatatccttc caggctccct tttgcaaagc
    21181 cttactcata ctgattgaac tcttcttaaa gaaaaagtaa ccaatattct ttttcgaatc
    21241 ggacgattct aaaaagacac tttgggtttc aggataatcc ttttcttgtt ctgtaaggga
    21301 ggcttcttta tcattgacat agactttata tggattactt gattccagtt ttctctggtc
    21361 aattgtagtt gcagcagtat ctgttgaagt gttttggata ttgcttccta aaaaggcgat
    21421 cttatccttt agcataaacc agctcttatg agcagtcaat gtttgattcc agttggtgaa
    21481 atccatggtt gctgtcgcat tggcatcatc tagtttgctc gttccaacga aagcagacgg
    21541 taaaacttta cctgtatcgc tatccgctct cttagcatcc gtctctgttg taccaggcat
    21601 cttatatgga ttaactgttg gccagtagcc atcgctatag tgactcaaat cgccattgta
    21661 aagatagaac atcccatcac tcgtatacca accatgttta ttttccttgt tcatgtgttc
    21721 gtaattcaag gtacgactgg aaaagagtga caagccaaat ccaaaccctt tctctgcgtt
    21781 gtacatggct gttttatcca tcttgttaaa ggcagatagg taacttgttc ttggaacact
    21841 tgcgactcct gcatcactta acaaggattg catcaaactg atatccttat aagtcttcaa
    21901 attcttaaag acatcataat aactatccga ttgaacaatg gtcttcacaa gactctgcaa
    21961 acgttgtttg gtttctcctt cagacatatc cgctattcgg tgaatccctc ttagtacttc
    22021 tactgcggcc acgtgcccct cgctatttgc acgactgatc gagcgtccac gactcatatc
    22081 catcaactct ccattcacca gcaaaggagc aaacgattta tcaatccagt ggtacatggt
    22141 ttgcatttta tctttatcga ttggactctt ggtcttttga atgactggca acagttgaga
    22201 caggccatca atcaaaacat tcccataagc acccgtatag gcaacattgg tgtggtcgat
    22261 ataggatcca tcttgataaa aaccttcacc ttgctctacc aacttgaaca cttgctcaat
    22321 cgagcgaatg gtagaagaaa tttcttgatc atccttacgc agtaaaccag ctattacttt
    22381 tacccttccc atatcaacta agtttccacc tagagccttg aatgggttat cagtcgtctt
    22441 tcggaaatgt tcgggatctg gtacaaattt ttcaatcaca tctgtatatt ttttaatttc
    22501 ctcatcagag aagtattctt tcatcagaga caaggtattg ttgatggcac gaggtgtacc
    22561 gatttcataa tcccaccagt tcccaacaat gctcttttca ctattgtaga catatttatg
    22621 cagccattcc atggaatccc tgactgttcg aacgacagtt tcatcttgat aataacgaga
    22681 agaaggattg gtcacttgct tggccatctc ctccaatttc cgataagtgg cagtcagatt
    22741 tgcagacatt ttataatttg aaaatttttc ccacaaatag gtgcggtccg cctgacttga
    22801 aatactagat aggctatcag ctacctttcc ttccaattcc tggtttaatt tggccatctg
    22861 ttcattttta gaatcatagt attgattccc agcgatgatg ccattccagt catccaaacg
    22921 ggctgtgtat gcatccttaa cagaggctag aatcttcaaa ggaatctttt tcacttcctt
    22981 gccatcttta ctgacaatga cattggttgt cccttcctta agaggttcta aaattccatt
    23041 tttgactgaa gcaacgtcag gattttctac cttataagta tagtccgcaa gagaaaaaac
    23101 atgttttttt ccaattggta aatcaatctt ttcctcaagc tgtttatctg tttgagaatc
    23161 ctcagaaagc tggtctgcta cctctaccag ctcaatatcc ttaaaggaaa cagtcccagt
    23221 tcctgtttca tagaataact ccagcttgat tttatcaaca tctaaagtcg ggctatagtc
    23281 tgcttcaatg gtctgccagt cctttgttcc tgacgtcgtt gcagaattcc acaatcgctt
    23341 gtccttacca ctttcctcaa tgatacgaac tttggcaatc ccgattttat tatctgtttt
    23401 aatcttgaaa cgcagtttat actttttctt agcttcaata ggaaccatac ggtgaagcgc
    23461 tgcccttaat ttctcatggc ttgagatagt gatagcccca tccttagcct caatgactcg
    23521 agttgaggca tctgcactat tcttctggtc tacccaagct gaccacccct gagctttgct
    23581 tcctgtccac ggactgcttc cgtcctccgt ctgaccaaaa tcaccatttt caactaaatt
    23641 ttttgtatcc ctttgctgat actgaacttc cttctggctt tgctgaatgg tattcgtagt
    23701 cgtttcttcc gctccaattg tcatataatg gtttaataaa aatcctgata aaacaagtga
    23761 agacaaactc acaatgagct tctttgtttt tgtttgcatg tatacactcc aataaacata
    23821 ttgtaaaatc aataggaact aaatctcaaa ttagagattt atagcaacta agtaaaccgg
    23881 tttaattaaa tcataccatt tttaaagtta tttgtaaacg gtttctatca tattgaaggc
    23941 ttattcttca acaatatctt ccatccgact cgacgaaaaa agtaaaaact gttacaatgt
    24001 agaaaaagaa aagaggccct catgacttca ctttatgatt tttccgtttt gaaccaaaac
    24061 aaccaagcaa ctcccttgga tagctatcgt ggcaaagttc tcttgattgt caacactgct
    24121 actggatgtg gtttaacgcc ccagtaccag ggacttcaag aactctatga acgctatcaa
    24181 gatcagggct tcgaaatatt ggatttccct tgcaatcagt ttatgggaca agcacccggc
    24241 agcgcagagg aaatcaacgc cttctgtagc ctacattttc aaaccacctt cccacgtttt
    24301 gccaagatta aggtcaacgg taaggaagca gaccctctct atgtctggtt acaagaccag
    24361 aaatccggcc cactaggaaa acgagtcgaa tggaatttcg ctaagtttct catcggtcga
    24421 gatgggcaag tctttgaacg cttttcttca aaaacagacc caaaacaaat tgaagaggcg
    24481 atacaaactc tactataatt cacaatctca ctatgattag gtttccttta acctgatgaa
    24541 tagtgagatt ttttgatggg ctttgactta aatagaaaaa caccccatga tatgaaacat
    24601 gaagtgttgt aaagtctatg ttgtaggtgc ttatttcaca atttcaatgt gaccagtgat
    24661 aacgaatacc atacagaatc ttcatataca ctaaacaaat gactttctaa ttatttcaat
    24721 tagttttggc tagtaaatat catttccaac aaacgccctc tcaattcctt atcctgatga
    24781 tgcaagatat tcattaagtc atgagagttt ttcgcattga tgaattgatt taacaatcta
    24841 tcttttaatt catatggaag agaagctgtc tttagtagtc taaaaacttc gtcatttaaa
    24901 gatgtccttt tattatcttt ccattcaaat ttagctgtat cattcttatt tggcaattca
    24961 attatagaca cattcgttcc tttaaaatga attctatgtt ttctattgct tggaacgata
    25021 ctagaatctc cttgtaatgc taactctacc attcccattt cccaatcgat tgataatctt
    25081 gttttatatc tttgaccatt ttgatcttca agcatttcaa aagaatgttg ttttcctggg
    25141 aatacatacc aatctacaac ttcaggtaaa tcaacaccca tacctatctc agaaccaacc
    25201 aagggaatga ttgcaccact ttttgcaaac acaggcgtag tcgagatgtc cctataaaca
    25261 cttaacttca caccacctgt gtattttttc tctgaaaaga agtcatacca ttcaccttca
    25321 gggaaccata catctacttt tgcagattgg aatgtcaaat ccatcttttc tacaatggga
    25381 gccaccatca gttctgttcc aaaaaagtat tggtttggaa cattatagct ctcatcattc
    25441 tctggataga aataatagat tggactgatt aatggggcac cttcctcatg tgtctgtaca
    25501 ttcatggtat atagataggg aatcatctga tgtctcaaac gaaggtattt cttcataatc
    25561 ttagatgttg tttctgaaaa aaaccaaggt tctttactat taaaaggact tctagaacta
    25621 tgtaatcgag taatcggact aaaaacacca aactgtagcc atctagtttg tagctcttcg
    25681 tcataatccc ccaacatatg tccaccgata tcatgactcc accaactata accgatatta
    25741 gatgctgtcg ctgtaaaata gggttgaaat cttaaggaat tccaactaat aatagtatcc
    25801 cctgaaaaac caacagggta gcggtgacta ccaggacctg catatcttga taaaatcaaa
    25861 ccaccttctg catttttaca actatcctga tagtgataat ggtttaaaag ccaaagtgga
    25921 tctagcatac cttgtgtccc ttgttgccag tcaatccacc aaaaatctac tccctgcttt
    25981 tctagttcat aatgaacatc tttaaagtag gcttccctaa aagagggatt aaaaaaatca
    26041 aaaatagcag gttcttctag ttctacattt aaccccaacc gttttgcgat ttgaggataa
    26101 gcttcttcat aagcccgtat cccatcagca ggatggacat ttaaggagag ttttagcttt
    26161 ctatcatgaa gttgttgcaa taactgttct ggatttggta ttaagtttct attccaacta
    26221 tatcctgtcc agccacttcc aaagcgagct ggaatgtcag ttatatgcca atccatatct
    26281 aacacaccga tagataatgg aattttctct gtttcaaatc tgtctattaa atccaagtat
    26341 tcatccgacg tataaggcca atatctactc caccaattgc ctaaagcata tcttggcaac
    26401 aagggtgttg aaccagtcaa atggtaaaaa tctctgattg ctcctctata atcatgccca
    26461 taggcaaaga aatacaggtc aatttgattt tctctctcaa tataaccaga ttgttcatcc
    26521 caaataaatc cttgagaatc atccaataag gctataccat ttcggctaat aattccatct
    26581 tctaacgaga ttgctccatc tgccttatcc agagtccgag ctgttccttt taacgtttca
    26641 atagattcac caaaatacca gcgactacca tatacggcaa aatttccttt taattctata
    26701 aataaatttt cggcgttaaa ttctccttta ttaaagtgca gatgaaaata gtccgtcata
    26761 atatctagta cgtttgatgt ctcgatataa tctaacgaaa tttggccaaa atctctatta
    26821 tagataagtt gtgtcgttct atcctcaaaa cttccagttt gagagtattc taaccttact
    26881 agcttgtctg ttaatacaga gattcgataa aactctccct taaaaatttt caatttgttt
    26941 tcctcctttt atggtagcat aaaaacagaa cgcaccattt ttgatgcgtt tttcattatt
    27001 ctgaatgcaa tgttctatct gttatatcta tgacaaataa tagtcaattg aaaaaaatgt
    27061 agtggacaaa atatctttta acaaaccaag agtttattaa agagttatca cttttcaact
    27121 tttctaagct tatgcagttg tgaaacaaac tacttttaaa ctattaacta agataggatt
    27181 gataaataat ttcaaactct tactagcaat catacgatat tcaagctcgc gtgctttttt
    27241 ccttcctgct tatttcttag aactgaagaa cccggatcgg tatataaatt atccggatca
    27301 acatagtcat aagactcata acagttgcgc ttcattaagt catccccaga gcaagagctt
    27361 catctcgtaa tttttcaaca tcactaaccg taggtcgcca tccttcaatc atatttgtac
    27421 ttaaagcata ccaaacactc ttaaaaacgg atcggttttc aaaagctatt cccatgattg
    27481 tcatcttttc tttatctata tctaaggaca tatgctacct cctttagata cattatacca
    27541 tgtttctctg tagcttttaa aaattttatt ttgtttgtca tatctaagtt ttcagcacgc
    27601 ttatcctatt ttataaacct caaacccaaa tataaaacgc attctttttg cttttttact
    27661 attgtatcgt attctacgat aacatacttt actttattgt ttttttaaat aacagcaatt
    27721 ccctgtttat caactattcg aactactttc tattttgctt cataccctac atagcgaaaa
    27781 aatatgaaaa agcagagaag aatatcttaa aaagacctct tcactgctaa tgttaacgct
    27841 cattatttaa actatatgga ttctatcatc gagtatactt ttttacttat tagatacctt
    27901 gctcttcttt caccaatttt tgatcatata cacggatgaa tggaagatag actaagaatg
    27961 ctgcaaatgc acatactaga gcaactaata cagctcgaag atctgctgtc cctaagaaag
    28021 ctccaatccc tactggagtt ggccatggaa cctgtgcgat aattggctta ataaagttta
    28081 gagaattcgc tacgtaataa atagtagcag taaccattgg tgctaaaata aatggtatag
    28141 ccaaggctgg attatagata ataggtaatc caaaaattaa tggttcatta atattaaata
    28201 aggctggaac tacagatgct cgtcctattg ctttaagctg ttcagattta gaggcaaaag
    28261 caatatataa acatagtcct aaagttgcac cagaaccacc tgcaattaca aacatattag
    28321 aaaattcacc tgcaacagcg aagtgcccgc cagcagcatt ttcagccatg ttagcaagag
    28381 caattggact aacaaatgca aaaacaatgt tcgcaccgtg gatacctaca atccaaagta
    28441 gttgagtcaa tagataaata atcattaaac caatccacga attagtcaga ttggatacaa
    28501 aaccaaatgg aattgcaatg actttaaaaa tatctgttcc cattgctaca agaagaccgt
    28561 tgataaagat aacaacaaat gcaacaacaa atcccggaac caaagcggta aatccacgag
    28621 aaactccttc tggaacagct tcaggcattt taataaccca attatgttta acacacatac
    28681 gataaataag aacagtcaca attgccataa tgattgcggt aaaaatccct gttgtcccaa
    28741 aacgtgcgac tccatttccc attgcccatc catctgcaat tactgctcct tcttttagac
    28801 ttgtcacagt cttcatcatt ccaccatcaa aaatgatttg cggtactgtc atgacaaaag
    28861 ccatcaaggc aagcaaggca ccattaagag gattcatatt gagttcttcc tcctctgcat
    28921 aaatttttgt caattcatat gcaagtgata gaacgaaata aagagataga gaacccatag
    28981 tcgcatagtt tgcaaccatg taaagtgatg tgaatttatc aaatgaagca gagaaaatat
    29041 ctgccacaat tggccaaaat gagaaagctt gtggcaaaat actgaatacc aaaaacattg
    29101 atcctacaat agtaaatggt acagcagcca tacctgcagc cgtgatagca cgtactactt
    29161 taaactgagc aagtttgccc attggtccca taacatggtt ttcaagaaaa ccaaacaacc
    29221 cgttttgttg atccataaat agacctcctt aataaaacat aataattttt actttctaaa
    29281 gactagtttc aaatacaaat tatactagat caggattata aactaagtga gttcttttcc
    29341 aattggacaa attgttgata agccttatct gttcgtttat aaattttttt aattcttcta
    29401 atgtctaaca aactcagaac taaacctaat agaagaacta caaaaacaaa taaacgtgct
    29461 acttggttat tttcaaaaat cggaaaaaga ttcttaaacc aacttgtcca agttaaaaca
    29521 agtaatccta ttgaaataag catttgtatt ctaacaaaca ttagtgttat tcccaacttt
    29581 tctttcctat ttccatagag tttaaattgt tcaacagttg ctaaaataga aaatactatg
    29641 agcataatgg ggaaaataat aataggcgag ggactaataa actgactcaa aagccaataa
    29701 atattcccaa aaaagaagag tgctattgaa taacgtagaa gaagatatcg attgaaaaaa
    29761 gtattagtta gagccatctc tcgacgttgt tgttcaatct tttgtcgttc ttttttatcc
    29821 atatcatttc ctccttatat aacaacacat atttagttaa ctttcttata aagagctaac
    29881 atttcctttg ctacttctaa taatgtcata gtggtcatta aatgatcttg agcatgtacc
    29941 atgataattt caattttaat ttccactcca cttgcgtatt cttgcaagag tttggtttgt
    30001 gcatgatgcg cttcaagaat tatctcattt gattgattta atttactttc tgcatcatca
    30061 aaactacctt ctctcatttt tgcaaatgct tcatgtattt ctgaccttgc atttcccgaa
    30121 tgcaggataa tttcaaatgc tgcaacctgc agttcctctt gattcatatg aacctcctat
    30181 tttatcttct caaatatgtt aataaaatct tcaaagttat tgcaagatat tagctgattt
    30241 tgcaattcat cattctctgt cagagagact atctttttag tcacagttgc caaaccttcg
    30301 ttcccatata ttgatggaga tagaagaaat actagctgga catgtgaact ttgattatcc
    30361 cagagtaacg aatctttaca aattgcaacc gaaacctttc cctctgtacc aaaggactga
    30421 ataggatgcg gaactgcaat tttttcagaa aaaacaactg aacttaattc ttcgcgctgt
    30481 ttaattccat aaagtaaaga ttgttcaaac tcatttgatt caccaacaga taaactctca
    30541 accatctttt caagtaaatt taccttgtct gattcagtac atattaaaaa gttttcttta
    30601 ctaaaatact gtctaaagcc gttgttttca aatttgttaa tctttgatga ttgtacataa
    30661 ctagaaactt gcatctgatc catagctttt ctaatcattt ccatctcatc actcttaaga
    30721 aacacactaa ctttaaaaac tgggatttga aaatatagat ttgataaatc aacagctgac
    30781 actataaaat ctattccttt aagtttttct tgattcaatt cataatagcc tattacatca
    30841 acaacttcta ctcgcttccc aaactccgtt tccaaacgat ttcttaacat ttgggctgca
    30901 ccaaatcctg ttgcacaaat agcaagaata ttaaacttag tactctcttt gctacgttcc
    30961 atagcagcta aaaagtgaag acttacatat gctacttcat catctgatat tgtccactcc
    31021 aagaacttgt ccatatttgc aagaatttct ctagtcataa agaatatatc actataattc
    31081 tgtttaattt catctaccaa agggttattt aaggtaatcc ggctttctaa acgtacttgt
    31141 agtgtcatta gatgagttat caatccttca attagttgga aatctgaaga aaagttatac
    31201 atatcatcta atcctaaatt ctgaaatgtt ttaagtaaag atttttttaa aacttcttca
    31261 gaaatattct tctgattttt ttgacattgt tgactcttag ctaacaaatg caaagtaatg
    31321 tagtctattt cctgaactgg aaattcctga tttgttactt ctcttacttt agaaagaatt
    31381 ctttgggcaa cctttctctc tattgcatca tcagtcatct gacagtctat attttttatt
    31441 tcaaatccgg attttaaacg aatcacagac aatgctatgt gaactactaa attctgtagt
    31501 acaaaatcag atagttttag gttggcctct tggcattcat ccaaaacaat tctagcaaat
    31561 tcttctaatg gaacagtttg atcaaaaaag ttaaatttta catagcaatg tattgtttta
    31621 aaaaattgat tctctaggaa ataatttatg ataaaacgtc gtttatcacg ttcctcgcct
    31681 gagacataaa ctcctttatt cgccctactc tcaatggaca aattatactc tgataacatc
    31741 actcgtatct ttctgaaatc atgagataat gttgaacggc taacgtaaag ttcatcagct
    31801 aaatcatcaa aaagaactgg aacttgctca aataataatt tatttaagat aaatactaaa
    31861 cgatcatcac cttttgaaac cgcagttttc gtatagtctt cttccagttc ataagtttgt
    31921 ctaaactcct ggtaagcgcc ttgattctca aaaaatattt gatacccttg accttgtttt
    31981 gaaatcaacc ggactccttg aataatcatt gtcttctcaa ttaatttcag tacattacgg
    32041 acagttctat ctgaacagga taaatattct gccagttctt tgcttgtaac aaaacgttcc
    32101 ttatttttta ttaaaaattg aaggatatct ttctctttaa tgtttaacac attcattccc
    32161 tcctaaaacg tatgttttca tatattgaag catattatac acttaaatca atttatatca
    32221 aactcaaaac aatttatctt aacttaaata tttattgaca tttcatgtgt tcatcaaata
    32281 ttctcaagaa tcaaattagc cattttttca attcccattg gaataggaat ataggcttga
    32341 ggaggtattt gtacaactgg ttttcctgct ttagaaccag cctcttcaaa ttgcttaaag
    32401 tacatttttg tttgaggact gacaagatac aaatcaaaag ctgctgctgc gatagctttc
    32461 cctccttcag tagcactaat agcatcaact acaatatctt tcccttttcc ttttagaaac
    32521 tctgttgttt tctgtgccat aagtgatgaa gacattcctg ctgcacaaat aattaaagct
    32581 tttgccataa tattttctcc ttttcttaaa tccaatcaaa gctgtgctaa gttggcttat
    32641 ttgttatcta tttttattat aaaataaagc gtttccaatg acaattccct cattttccta
    32701 aatgatatgg aaaaaaatta tttatacttc aatttataaa ataaaattat tcctgagagt
    32761 agaaatgaaa cactatttgc taaaatcaaa ggcaagtctc ctatacgaat accatgagca
    32821 agccacaatg caataccaat aacttgcata acatacatac ctagagcaat agatcctgtg
    32881 tcctttgtct taactacacg aaaaacttgt ggtaaaaatg caaatgttgt taaaattgct
    32941 gcaatacttc caatcatatg tcaccccaat atgctaaaca aactgagaat aatctcagtt
    33001 tgtttatact attctactga ttcaccgtta gatgaaataa cttccttata ccagccaaaa
    33061 gattttttcg gggaacgatt ataacttccc ttcccattat catctttatc tacataaata
    33121 aagccataac gtttccgcat ttcaccggta ccagctgaaa ccaaatcaat acatccccat
    33181 ggagtataac ccattaaatc aacaccatct tcaactacag cctttttcat ttcacgaata
    33241 tgggcaccta gatattcaat tctataatca tcatgtatca taccatctgc tgcaacttga
    33301 tctatagctc caaaaccatt ttcaacaata aagagtggta agtgatagtg gtctgtaaac
    33361 caatttaacg cataacgcaa accttctgga tcaatttgcc acttccattc agaagcctta
    33421 acataattat ttttcactaa atcttctgtt tcaagataat caaaataagg attattttca
    33481 cgatgagagt ctatagcaaa ggacatatag taactgaaac caatgtaatc tacagtccca
    33541 ccaagtaaat cttctttatc ctggtcagta aaatcaactg aaataccttt tcgttcccaa
    33601 tacttgaaaa tatgctcagg atatttacct aaaacatgca catcagcaaa ataataacgc
    33661 ttctgcatag ctttcattgc cattaagata tccttaggat tgcaagtaac tggataaatt
    33721 ggacacatcg caatcataca acctatttga aaatctggat taatctcatg accaattttt
    33781 acagctcgtg cagaagcaac taattcgtaa tgtgctgctt gatacataat tgcctctcta
    33841 ttatcacctt cctcatatac aatacctgag ttagtaaatg gtgcaaaatc ttcctgataa
    33901 ttcgcttgat tattgatttc attgaaagtc atccaatatt taaccttatc tttgtaacgt
    33961 ttaaatacga cttctgcaaa acgagcaaag aaatcaatca atttcctatt tttccaacca
    34021 ccatattcgg tcactaagtg ataaggcatt tcaaaatgag atagagtgat gacaggttca
    34081 ataccattct ttaagcattc atcaaaaaga ttatcataaa actgtaatcc ttcttcattc
    34141 ggctctaact catcaccttt tggaaagata cgtgtccatg caagagaggt acggaagcac
    34201 ttgaatccca tttcagcaaa aagtgctatg tcttctttat aacgatgata aaaatctatc
    34261 gcctcatgat ttggataata tttaccctct aaaactccca aagtaatttc acgagctact
    34321 ccatgacgac cagcagtcat aacatcagca acactaattc ccttgccacc ttcttgccat
    34381 ccaccttcaa gttgatgagc agcaacagca ccaccccata aaaatccatc tttaaaagta
    34441 gtcatctttt ttcctcctga ctttgatact cttattataa acctcaaatc aaaagatgaa
    34501 aacgcattct ttttccttat tgttaaggaa agaagtaatt tttaatggaa atagaacaat
    34561 atcttcttgt attctcgtaa tgatatcttt acgattttca atactttcaa actacaaaaa
    34621 ctctcacaat aattctaatt ccctgtgtct ataaacgact tatcgctttc tggcatccca
    34681 gaatcatctt ctatataacg ttcaacttgc atctgcaagt gatatttttt tcttaaatct
    34741 aagattttct gcattgtctt tgattgatga tgttcatcta aagcttcttg atttatccac
    34801 tgatcaataa ggagaatagt tccctctttt tcaattggta aaaaatattc gtatttcaag
    34861 ttaccttttt gatttctaat ttcttcaaca aggccactat caagcatttc tcttgcaaac
    34921 tttattgcac tatctccatc acctttataa tatacatgaa tagtcaatgt catcttatat
    34981 cctccaaaat catccttcaa tttaaaaaaa acaagtttag atgaggatct aaacttgttt
    35041 tttatgaact aattatctaa cgtttcgcca ttactttcaa tcacttcttt ataccaataa
    35101 aatgattttt tcttatagcg atttatagtc aattgaaaca agagcaggac aaaagagcct
    35161 cataaaaggt attgcaactt ggtaatacct ttttgaggtg ctttttgata tgagcccatg
    35221 ttttctcaat aggattgtac tcaggtgagt agggaggaag aggtaaaagt ttatacccaa
    35281 actcttcaca caagagttct agcttcccca ttctatggaa tcttgcatta tccataatat
    35341 agtagattga aactagaata gtacacctct acttctaaaa cattgttaga attcgatttg
    35401 actatcctcg atttgtccta ttcttatttc acattactat aaaaataagg taaacttttc
    35461 aaaaaagcac gaaaaaagca cccataaggt aaacttttga gtgctttgaa acattgatat
    35521 aatcgtattg attaacgttt tgaggcaact gaccttgtca ggttgcagcc acatttgtaa
    35581 gcgactaaag tcgcaacaac tgtgtcaatt gcaccaattt agtaagaaag tataaaaaaa
    35641 gaacaccccg aaaggtgctc tgtataagta tagtaattct ttcgaattaa cgtttactaa
    35701 attgtgatgc tttacgagct ttcttaagac ctggtttctt acgttcaact ttacgtgagt
    35761 cacgtgtaag aagtcctgcg cgtttcaatg aatcgcggaa gtctgggtct acttgaagaa
    35821 gggcacgagc gataccgtga cggatagctc ctgattgacc agcgtatcca ccacctacaa
    35881 cgttaacgaa aacgtcgtat gaacctacag ttgaagtaac tgcgaatggt tggttgatga
    35941 caagacgaag gtcagcgtgt gggatgtact cttcaacatc ttttttgtta acagtgattt
    36001 taccagttcc tggaacaagg cgaacgcgtg caacagcgtt tttacgacgt ccagtacctg
    36061 catattgtgc ttgtgacata ctttattgtt cctttcctta gataagtcct gaaatgtcaa
    36121 gaacttctgg ttgttgtgca gcgtgagtgt gctcagctcc aacaaatact ttcaacttca
    36181 taccttgagc gcgtccaagt gtattgtgtg gaagcatacc tttaactgat ttctcaatca
    36241 aacgtactgc atttttagaa cgaagttcac ctgcagagat ttgtttcaat ccacctgggt
    36301 ggtttgagtg agtgtagtag attttatcag ttgctttttt accagtcaat ttaacttttt
    36361 cagcattgac aacaatcacg aagtcacctg tatcagtgtg tggtgtaaat gttggtttgt
    36421 tttttccgcg aagtacgcta gcaactactg cagaaagacg tccaagtggt acatcagttg
    36481 cgtcaactac gtaccattta cgttcaactt ggcctggttt agccataaat gttgttttgt
    36541 tcatgatttc tcctatatat agttcgattt ttgtttacgg tgatgggtgt tccttcccat
    36601 cgaaaagtat ttggaaggtt ccggggcctt tcaaatgggg taaacaatac cgcctactat
    36661 cataccaaat ttcaccccta aaagtcaata gatatgaaaa atatttttcg gtaacttctc
    36721 aaagtaactg aaagttatat aatcaagtta atttgggaat ttacctatta acttcggtag
    36781 atttttggga atttttttcc ttctttttcc ttgtagttaa aatccttttc aaaaaatcac
    36841 cttttcttga tttttaatcc tatttgctgt atgataaggg aaaagaaagg ggacagagat
    36901 atggctttta ccaataccca catgcggtct gctagttttg gcattgttac cagcttgccc
    36961 gatgacatca ttgactcttt ttggtatatc atcgatcatt tcttaaaaaa tgtctttgaa
    37021 ttggaagaag aactcgagtt tcaattgctt aataaccaag gaaagattac cttccacttt
    37081 tcaagtcaac acctccctac agccattgat tttgacttta accacccttt cgaccctcgt
    37141 tatcccccaa gagtactggt tttagacatg gacggtagag aaactatcct cctcccagaa
    37201 gaaaatgacc tattttaaaa actctagcct tcagttgcaa gtaactgaaa actagagttt
    37261 ttctattttt tcaaagcatc atacaagttg cggatcggtt gttttaatat cggatggata
    37321 aaatgaggcg caatttcctg taaggactca aggacaaaaa ggcgttccgc tatgtaagga
    37381 tgaggcaata tgaggtcgtc tgtataaagg atctggtcct ccacaaagag caagtccaaa
    37441 tcaatcaaac gaggtcccca atgcacttct ctcacccgtc ccagctctga ctcaatggct
    37501 aacaaggttt ctaacaagtc ttgtgctggt agccaggttt ccacctcaac cacttgattg
    37561 gcaaagctat cctgctccac tccaccccaa ggctccgtcg ctaagacact ggactctttg
    37621 agaatataga tgccacgagc tcgcattttc tcaatggctt gtttcaagtt tgcttgttta
    37681 tctcccatat tgcttcctag ggcgataaag gctcgttgct tgcggcgatg aatggttacc
    37741 gagcaagtat ctagtgacaa atgcaccggt gcccaaggtt ttttcagttc caacttcatt
    37801 tcttggacaa gaggataaga ctcaaaggta cgttccacca gtttataggc taccgtttca
    37861 atcaaatctt cactcgtttc ctgaaaccaa gtcgtccact gctgacacaa ttctccgtaa
    37921 tggacagagg ctgttaaatc caagtctgta gctgccttgg tcatatcata ggataggatg
    37981 gctgaaacga caaatttctg ccccaattct ttctcactag gaaaaagacc atgataggca
    38041 aacatttcca aatccttaat ctgcagttga tccataatga ttcctttcta gaaaaatccg
    38101 cttaaagcgg attcttttta tagccccatt aaacgataag cttgatcgcg gaggtcctta
    38161 tctgtttcaa atagaccacg agctactgtc gtcaaggttg cagtacctgg ttttctaaca
    38221 ccacgcatac tcatacacat atgttccgcc tcaatgacaa caaaggctcc tttagcacct
    38281 agatagtcca tcaaggcatc ggccacttcg atattcaaac gttcttgaat ttgtggtttt
    38341 ttcgaataaa cttcaaccgt acgggctagc ttagacaagc ctgccacacg accatctgga
    38401 atgtaggcaa tgtgcgctct accataaaat ggcaagaagt ggtgttcaca catggtatgg
    38461 aaaaagatat ccttttctac caccatatta tcgtcaataa tttcaaagga ttttgacaaa
    38521 tgttcctctg ctgtttgacc aagacctgaa aaaatctctt gatacatacg ggctacacga
    38581 gcaggtgttt cctgcaagcc ctcgcgatta gcgttctctc ctacagcctc gataatcatt
    38641 tttacagctg cttcaatctt ttgtgtatcc attctcgttc ttcctctcca tcagataggc
    38701 cctcacttgg ctcaagaaat acaaggaacc tgtgacaatc ctaactgttt gtttctcttc
    38761 ttttttatct gtcaaattct gctctagaaa atcatgccaa tcttggtagc tgagatttct
    38821 agacttagct gcctctttca gcacgctttc atccgtcgcc cgactatccg caaaatgtgt
    38881 tagagtaagc tcggtatctg gcatggctcc cagcaagtcc aacatatcct ccaaggcttt
    38941 ggttttgata caagtgaaga ggatttcctt atgataatcc gcaaaacgtt cttgcaaggt
    39001 taccaacaag gccttgatag catggggatt atgggctcca tccaaaatca tcaagggatc
    39061 tcttgacacg atttccaaac gccctggcca acttgtttct tccaaggctt gaccaagaaa
    39121 gtcattgctt gctagctctc gaccatcttc ttgacaaaaa gtatcaagta aagctatggc
    39181 catcccagca ttctctattt ggtacaaacc aagcaggcta gtctggaagc gaccttgtct
    39241 gacagcactt gtatagtcaa agacttcccc tgtcaccaca ctttcttgat gacgaacctg
    39301 ataatctgtc ccgtaggcaa gtctcggcgc atctttccct tccgcaatgc ggtcaatcac
    39361 agccaaggct tctggagcaa tacgccctgt taccaagggc atcccttgtt tgataatacc
    39421 tgccttctgc tctgctatgg cctccaaggt gtcaccaagt agggccacat gatccaagcc
    39481 aatagttgta attcctgtca aaatgggctg acagacattg gtactatcca aaagtccacc
    39541 catgccaact tccatgatgg ccacatctac ttgctctgag gcaaagtagt cataggccag
    39601 ggctgtgata atctcaaact cggttgtgcc ctgtaaattg gcgaccgctt ctccccccat
    39661 caaagactga tagtctgcca tgagagcttc tagcctcgct tctgagatcg attccccatt
    39721 gatgctaatc tggtctgtgt aatgaatgag atagggcgag ttaaacacgc caactctcag
    39781 ccctagcttt tctagcatct ttttcaaaaa agcaatagtc gagcccttgc cgttagtccc
    39841 tccgatatgg aggaccttga gtttgagatg gggattgcca cgcaaagcta acagttccac
    39901 cattcgttcc aaaccaaaat gcggttgatc cgtccggtag ttagcaatcc actgattgtt
    39961 ttcaatttct ttcatcttat ttatattgtt ttaaatctaa attttccgct tcatcagcca
    40021 gacgaatggc agaggcaatt tcaactgcca tcctgtgact agctacgtca tgcacgcgca
    40081 ccacttctac accctgtctc gcagcgatac tagttacatg agccgaagcc gtgtcccgat
    40141 ttcggaaacc aagctctgtc tcaggattga cttcaaaacc attctcctct aggatattga
    40201 tgacaaatcg cttgcgcgaa actccgagaa agattggata gcctttctga tgtagtttat
    40261 ccaggttccg taaaagaagc agattttctt tcttggtcag accaaagcca attcctggat
    40321 ccaacaggat attttctggt gcaataccag cttctgccgc tctcgctagt gctcgttcaa
    40381 agaaagccac catcaagtct tcgattggca atatttcaaa gtcagctaac tcttctactg
    40441 taaaagtttg attaaatcca aaatgaggga atatgagcga gctagggtgt tgaggtcgcg
    40501 ccataactgg attaaacatg atgaccactt gcgctctcgc ttcagctacc acatgagcca
    40561 ttttttcatc gcccatgaga ccagtgatat cattgactag atcggcacca gcagccaaag
    40621 cagcctctgc tacttgactc ttccaagtat caatagagat gaggacatca ctttccttgc
    40681 gaatcgcttt gatcactgga acaacacgct ggatttcctc ttctatctca acatagctac
    40741 tgcccggccg agtcgattct ccgccgatat cgagcatact ggctccttct gctatcaatt
    40801 tacgagcctg ctggagtgcc tgctcaagag caaaaaattg accaccgtcc gaaaaggagt
    40861 ctggggttac attgataatt ccgcaaataa ctgtctttgc atgattggct ttacttgaca
    40921 tatcggtcac tccctcaagg attttcatca tattattttt ctattttacc ataaaaagaa
    40981 aaagatggac acgattgcat tcatctttcc ctagtagaaa gaggtcggtt cctacataaa
    41041 aacttttaca cagaaattcc taatgtccga ctcataatca ccacaagagc caacaaacag
    41101 aaagcaatcc cattaacaat catgtgaagc aagatcgaca tttccaaacg ttgggtcttg
    41161 taggccgtcc aagatagaac tgtcgacata cctccataaa tcaataaaga aggtaaatta
    41221 cttggttgat gcaataaagc aaacacaatc gtaccgacta caaatcccaa gttctccttg
    41281 cctcggaaaa tctttttagg aacaatccca cggcacaaga tttcctcaca aatcggagca
    41341 agcaaggcta gcaagaagaa actggaaatc aacgaactat tttgaaccat atcgttaatc
    41401 tgagactggt tagctgttgt cgtctcattt gacagttgca acaagataga accaagtata
    41461 tttgacccga caataactaa ataactcaag cccaaacgtg ccaaatcttt agctctaaaa
    41521 aaagaaaaat taaaacttgc caattgcgtt ttacgagctc caataataaa tagagccaga
    41581 accacaattg aaaggccagc aactatcagc cctgactgta gcagggctac ttcttttaaa
    41641 gtcaaaatag aggtaaccac taggggaacc tgatataaaa ggacggcaag taaaaagacc
    41701 ataatccagc ctgcacgatt caacaattct ttccacatat ttttctcttt catcacctat
    41761 ctcctttgta ttaaaaaagg ggggaaatcc ccctgggtca ttctattata aggccatgct
    41821 gatgtagtta aggataaaca aggcatccaa aatccaaatc atggcatgaa catctttaac
    41881 ttgaccttta acaagcttag tcaaagtgta agtcaagaaa ccaactgcaa tcccttgagt
    41941 gatagagtag ctgaatccca taaagataga tgtgaagaag gcaggaactg cttcagacat
    42001 atcatcccaa tggatatttt tcaagctacc aagcatcata atcccaacga taatcaagat
    42061 tggagctgta gccgctgttg gtacgatcgc tagaagtggg ctaaagaagc ttgaaatcgc
    42121 aaaacagata gctacaacca aggctgtcaa accagtacgt ccacctgcac cgataccagc
    42181 agcagactca acataagtcg ttacgtttga agtacctgca atagcaccga ctgtcgttcc
    42241 aatcaaatca gagtaaagag ccttatccaa tttggctgat tggtgatttt caccatttgt
    42301 cgctacgata ccaacttttt cacctgtacc gatcaaggta ccaattgtgt caaaaatatc
    42361 tgtcaatgag aaggcaagaa tggccatcag agtttcaggc aagcgagctg tatctgaaac
    42421 caaagctccc aaaccttctg aaccaagagc tgcaccaaag attgtcttca aatcttcaaa
    42481 agctgcacca acatggttat tagcaaaatc gatactagac aaatcaacca aaccaactgc
    42541 aatagcaaga acagttgttg tcaagataga gagaataatt ccccctttaa tccctttgat
    42601 gacaaagaag atagtaatgg caagtcctgc aagagccact aaaacagctg gattattaaa
    42661 gctgaccaat cctggaactg ctgaagagtt tgctgcaatc gttgcttgag ctttgtcagc
    42721 cccttctcct acaacagtat agttgcctgg atcaatcgtg aatttcaaaa gtccagcatt
    42781 cttaatccct acataggcaa ggaagacacc gataccagct gaaatagctg agcgaagagc
    42841 attgggaatc gattcaatga tcattttacg aacatttgtc aaggtaataa tcaatgaaat
    42901 aatcccacag atgaagacca tagctagggc ttcttgccaa gaataaccaa gcccgaatac
    42961 aactgtaaag gtaaagaagg cattgagtcc catacctggc gcttgggcat aaggtaagtt
    43021 agcataaaaa gccatcatca aggtacccgc tactgcacca ataatcgtcg ctaggaagac
    43081 gccctgagca ggcattcctg tttgtgaaag tatttgtggg tttacaaaga gaatatagct
    43141 cattgcaaag aaagttgtta aaccagcgag aacctctgta cgaacgtctg taccgttctc
    43201 ttttagttta aataatttgt ccatcatcaa tctcctttta atttttacga acaataatag
    43261 aattatatca tttatcattc actttttcaa tgtctttgtt tgatttgttt aagaaattaa
    43321 tccaatttca ttttttgttt ggaatctgct tttctgcctg ctttctgtta taatagaaga
    43381 catcttatct gaaaacacac tagaaaggtc catatgacga aaaaaattat tgcagttgac
    43441 ctggatggaa ccctgctcaa ctcagacagt caaatttctg actttaccaa aagaaccatc
    43501 aaaaaagttg ctgaaaaagg ccatcaggtt attattacga caggtcgccc ttaccgtatg
    43561 tcaaaagatt tttaccgtga actgggctta gacactccta tgattaactt caacggatcc
    43621 cttactcatt taccagacca agtttgggat tttgaaaagt gtttgactgt agacaaaaaa
    43681 tatctgctag atatggttca acgttcagag gacattcaag ccgattttat cgctggagaa
    43741 tatcgtaaaa aattctacat tacaaatccc aatgaagaaa ttgccaatcc caaactattt
    43801 ggtgtagaag ctttccagcc tgaagatcaa ttccagcctg aattggtgac caaggaccct
    43861 aactgtatcc tcttgcagac cagagccagt gacaaatatg ccttggcaaa agaaatgaac
    43921 gccttctacc agcatcaact ttctatcaat acctggggag gtccgctcaa tatccttgaa
    43981 tgtaccccaa aaggtgtcaa caagtccttt gctttggact acttgctcaa gataatgaat
    44041 cgtgacaaaa aagatttgat tgcctttgga gatgaacaca atgataccga aatgctcgct
    44101 tttgctggga agggttatgc catgaaaaat gccaatccag agctactccc ttatgcagat
    44161 gagcaaattt cccttaccaa cgaccaagat ggggttgcca aaaccctaca agacttattc
    44221 ttataaccta tactgatact caatgagaat caaagagcaa actaggaagc tagccgtagg
    44281 ttgctcaaag cactgctttg aggttgtaga tgaagctgac gtggtttgaa gagattttcg
    44341 aagagtatga ccagcttgca agctggtctt tgtgctcttt tcacagtctc atcaaccagt
    44401 taatcgattg ttctactttt tgtctccaaa accttggaaa aggctttctt ttgtgatata
    44461 cttcacatat aaatacaaga gagctcgtca cactcgactc tgttgacaaa aaatcaatcc
    44521 agtcccgttg tccctgttct cggtcaatat caaggaggat agctatgaaa gctgttgttg
    44581 taaatccaga aagcactggt gttgctattg aagaaaaagt actccgtcca cttgaaactg
    44641 gggaagcact tgtagaagtt gaatactgtg gtgtttgcca caccgacctc cacgttgctc
    44701 atggtgactt tggtcaagtc ccaggacgtg ttcttgggca cgaaggtatc ggtatcgtta
    44761 aagagattgc tccagatgtg aaaagcctta aagtcggtga ccgcgtcagc gttgcttggt
    44821 tctttgaagg atgtggcact tgcgaatact gtacaactgg tcgcgaaacc ctttgccgta
    44881 cagtgaaaaa tgctggctac tcagtagacg gtggtatggc tgaacaatgt atcgtaactg
    44941 ctgactatgc tgtcaaagtt cctgacggac ttgatccagc ccaagcttct tctatcacat
    45001 gtgctggagt aacaacctat aaagctatca aagaagcaaa agttgaacca ggccaatggg
    45061 ttgttcttta cggtgctggt ggacttggta acctcgctgt tcaatacgct aaaaaagtat
    45121 tcaatgctca tgttatcgca gtcgatatca acaatgacaa acttgccctt gcaaaagaag
    45181 taggcgctga cattgtgatt aacggcctcg aagttgaaga tgtagctgga ctcattaaag
    45241 aaaaaactga tggaggagct cattcagctg tcgtaactgc tgtgtctaaa gttgccttca
    45301 accaggctgt tgactccatt cgtgctggtg gtcgcgtcgt cgctgttggt cttccttctg
    45361 aaatgatgga actcagcatc gttaaaacag tcctcgatgg aatccaagtc atcggttctc
    45421 ttgtcggaac tcgtaaagac ttagaagaag ccttccaatt tggtgcagaa ggtctggtag
    45481 tcccagttgt tcaaaaacgt ccagtagaag atgctgttgc cattttcgac gaaatggaaa
    45541 aaggccaaat ccaaggacgt atggtactcg acttcaccca ctaatctaat agaaacctat
    45601 tttaaaagtt ggaagcttct tccaactttt ttatattaaa ttttaaataa gaattcaaga
    45661 ttactcctca aaaactcaac atatcaacat acaaaaataa aaatttttta attttttatg
    45721 ataaatagtt gcttttttta tgaaaacggt ttatacttaa acagtcttaa agttttctta
    45781 aatgaaaact aaaacaaaaa aggaggaatg acaataatga gtatcggaat cattattgcg
    45841 agccacggcg aatttgctgc gggtattcat cagtcaggat ctatgatctt tggtgaacaa
    45901 gaaaaggttc aagttgtgac ctttatgcca aatgaaggtc ctgatgatct atacgctaag
    45961 tttaataacg ctgttgctgc atttgacgca gaagatgagg ttctagtttt ggctgacctt
    46021 tggagtggtt ctccatttaa ccaagctagt cgcgtgatgg gagaaaatcc tgagcgtaag
    46081 tttgccatca tcacaggact taacttaccg atgttgattc aagcctacac agagcgcctc
    46141 atggacgctg ctgcaggtgt agaaaaagtc gctgctaata tcattaaaga agccaaagat
    46201 ggcatcaaag ctcttccaga agagctaaat ccagttgaag aagttgcaag cgctgcagct
    46261 gccccagttg cccaaactgc tatcccagaa ggaactgtta tcggagacgg taaattgaaa
    46321 atcaatcttg cccgtcttga cacacgtcta cttcacggtc aggttgcaac tgcttggact
    46381 ccagattcaa aagcaaatcg tatcatcgtt gcttcagata acgtggctaa agacgacctt
    46441 cgtaaagaat tgattaaaca agcagctcca ggtaatgtca aggctaacgt ggttccaatt
    46501 caaaaactga ttgagatttc aaaagaccca cgttttggag aaacacatgc ccttatcttg
    46561 tttgaaacac ctcaagatgc ccttcgtgcc atcgaaggcg gcgtgccaat caagactctt
    46621 aacgttggtt ctatggctca ctcaacaggt aaaacattgg tcaataccgt tttgtctatg
    46681 gacaaagaag atgttgctac atttgaaaaa atgcgtgact tgggtgttga atttgatgtc
    46741 cgtaaagtac caaatgattc taaaaaagat ttgtttgact tgattaacaa agccaatgtc
    46801 aaataagcca ttatttatga aaggatttta aacatgtcta ttatttctat ggttttagta
    46861 gtcgttgtag ccttctttgc aggtcttgaa ggcatcctcg accagttcca atttcaccaa
    46921 ccacttgtag cctgtaccct tattgggctt gtaacaggtc acttggaagc agggattatc
    46981 ctcggtggat cgcttcaaat gattgccctt ggttggtcaa atatcggtgc tgctatcgct
    47041 cctgatgctg cacttgcttc tgtcgctgct gccattatca tggttcttgg tggtgacttt
    47101 accaagactg gtatcggtgt tgcccaagcg gttgctatcc ctcttgccgt agctggtcta
    47161 ttcttaacta tgattgttcg tacaatttca gttggattgg ttcacactgc tgatgctgcc
    47221 gctaaaaaag gtgacttcgg cgctgtggag cgtgctcatt tcattgcgct acttttccaa
    47281 ggacttcgta tcgcgcttcc tgcagctctt ctccttatgg taccaactga aactgtacaa
    47341 agtatcctta gtgccatgcc agactggctc aaagatggta tggctatcgg tggtggtatg
    47401 gtcgttgccg ttggttacgc catggttatc aacatgatgg caactcgtga agtatggcca
    47461 ttcttcgctc ttggtttcgt tctcgctgct gtgtcagata ttactctaat cggattcggt
    47521 gctatcggtg ttgctatcgc tcttatctac cttcaccttt ctaaaactgg tggaaatggt
    47581 ggcggaggag ccgcaacttc taacgaccca atcggcgata tcctagaaga ctactaagat
    47641 aagaaaggac tgaaaacatc atgactgaaa aacttcaatt aactaaatca gatcgtaaaa
    47701 aagtttggtg gcgttcaacc ttcttacaag ggtcttggaa ctttgaacgg atgcaaaact
    47761 tgggctgggc ttatacactc attccagcta tcaaaaaact ctatactaaa aaagaagatc
    47821 aaatcgctgc tcttgagcgt caccttgagt tcttcaacac tcatccatac gtagctgctc
    47881 cagtcatggg ggttactctt gcgcttgaag aagaacgtgc taacggtgtg gaaatcgatg
    47941 acgctgctat ccaaggggtt aaaatcggta tgatgggacc tcttgctggt atcggtgacc
    48001 cagtattctg gtttacagta cgcccaatcc ttggatctct cggtgcttca cttgccctta
    48061 ctggcaatat cttggggcca ctcctcttct ttgttgcatg gaacttgatt cgtatgtcat
    48121 tcttgtggta tgttcaagag attggataca aggctggatc agaaatcact aaagatatgt
    48181 ctggtggtat ccttcaagat atcactaaag gagcttctat ccttgggatg ttcattcttg
    48241 ctgtccttgt tcaacgttgg gtaaatatta aatttgcttt cgatgtttct aaagttcaac
    48301 tagatgaaaa ggcttatatc cattgggata aattgccaga agggtctaaa ggtatccaag
    48361 aagcattcgc acaagtagga caaggattgt ctcaaactcc tgaaaaagtt actactttcc
    48421 aacaaaactt ggatatgttg attcctggat tatcaggact actccttact ttactttgca
    48481 tgtacttact taagaaaaaa gtatctccaa tcactattat ccttgccctc ttcgcagtgg
    48541 gtattgtggc acatgttctt cacatcatgt aatcaagcaa ctaaaaagga accaggttct
    48601 aaaatctgat tccttttttc tatgctttta ttcagccaag gctcccattg gatcccatgg
    48661 tgcaagtacg attggttctg ctccataggc agcttgttct tctgctgtca gcaattcctt
    48721 acgaacaacg atttggtatg tgtattcgtc catccaagcg tctgaggcaa caaagtaacc
    48781 atctgtacca accttgtctc cccatgagtt ttcaaccttc cacttggttg atttaccatt
    48841 ttcgtccaag tcaacacctg tcaagaccat ggcgtgggtc atcaagcttt cactatagtc
    48901 caaacgtcca gccttgtctt gagtaagttt aatgtccatg cttgattcaa agtcataaac
    48961 atctgtcgca aggatgccag ccttacggtt gctgagctgg ccgacatcag aaccaaacca
    49021 aacagtctca cctgcttgca tttgggcaat cgccaattct ttcaagcgct ccattggaac
    49081 gttgatgtag cgaactgcac ggctaccaac cacattcccc aacatctcaa ctgtgtaaga
    49141 ttttccgtaa ggtttatcag cagttggagc attgataaca gaaacgtagt cttctaaagg
    49201 aagattgaca tatttcttgt aaaactcttg tggtgtgatt cctttttcac ttttgtagtt
    49261 gttatcttta tcgcgataag caaagtcaaa cttgcgtggt ggaagtccta atgacatagc
    49321 aagaaagtta aagatttctt gcaagaggtc ttctttctta gcttgaacag tcgcttgatc
    49381 tgcaccagaa acaagcaaat cacgcaagat ttgagcatct tgacgaagca atttattaag
    49441 gatcgcattt agctcacgac tgctgctaga tgaaacagac tcaggataaa ctgacttagg
    49501 cacgacaccg tatttttcaa agagggaaac gaccatatcc cattgaccgc catcttgttg
    49561 aggtgtttgg agtaagaagc taaccttgcg gctagtcaat tcttggtctg aagtcgcaat
    49621 gacttgctcc aagaaccagt ttgatttctc atacttgtcc cagaagaaag tgtgggcttg
    49681 tgacaactca aagttctcca atttgtattg cgagatgagt ttgtggcgga aggtgttgag
    49741 agccgcaaac atccagcaac gaccagacgc tttctggtta gtgaccttgt ccttggttaa
    49801 atccaatgag aaaacaggtg tgttgtctac atggctttgg cgacgttcca gagctgcaaa
    49861 aattccgttg tggctggcag cattttcaat cgcttggtat tttacatttg cttcatagtt
    49921 ggcaaatagt ttatcagtaa atgattcttg aatcgcgttc atagattcct ccttttattc
    49981 tacagtctat tataactctt ttcacaaagg aagcaactaa aaaacataaa aggcgaggac
    50041 attgtccctc acctttttcg aatt
//
LOCUS       DBERXF010000011        48351 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.11, whole genome shotgun sequence.
ACCESSION   DBERXF010000011 DBERXF010000000
VERSION     DBERXF010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 48351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48351
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.11"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            9..89
                     /locus_tag="ACL8JK_000721"
     tRNA            9..89
                     /locus_tag="ACL8JK_000721"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Tyr,seq:gta)
     gene            94..164
                     /locus_tag="ACL8JK_000722"
     tRNA            94..164
                     /locus_tag="ACL8JK_000722"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:126..128,aa:Trp,seq:cca)
     gene            179..251
                     /locus_tag="ACL8JK_000723"
     tRNA            179..251
                     /locus_tag="ACL8JK_000723"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:212..214,aa:His,seq:gtg)
     gene            262..333
                     /locus_tag="ACL8JK_000724"
     tRNA            262..333
                     /locus_tag="ACL8JK_000724"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:294..296,aa:Gln,seq:ttg)
     gene            343..426
                     /locus_tag="ACL8JK_000725"
     tRNA            343..426
                     /locus_tag="ACL8JK_000725"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:377..379,aa:Leu,seq:caa)
     gene            533..1810
                     /locus_tag="ACL8JK_000726"
     CDS             533..1810
                     /locus_tag="ACL8JK_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HGS1785648.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDETDFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            1886..3370
                     /gene="thrC"
                     /locus_tag="ACL8JK_000727"
     CDS             1886..3370
                     /gene="thrC"
                     /locus_tag="ACL8JK_000727"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HGS1785649.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPDTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALRERLAA
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNDAVKTAKLMNALNSQGQYELTNFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQSATGDVTKTVIASTASPYKFPVVAVETVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMKAAVEAYLGL"
     gene            3431..4711
                     /locus_tag="ACL8JK_000728"
     CDS             3431..4711
                     /locus_tag="ACL8JK_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGS1785650.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLLGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4715..5335
                     /locus_tag="ACL8JK_000729"
     CDS             4715..5335
                     /locus_tag="ACL8JK_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS1785651.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLSQVRAQSLTEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5501..6643
                     /locus_tag="ACL8JK_000730"
     CDS             5501..6643
                     /locus_tag="ACL8JK_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGS1785652.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTS
                     SEAKEVASSNGATAAVSTYQPEETKTISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7071..7494
                     /locus_tag="ACL8JK_000731"
                     /pseudo
     CDS             7071..7494
                     /locus_tag="ACL8JK_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            7505..7864
                     /locus_tag="ACL8JK_000732"
     CDS             7505..7864
                     /locus_tag="ACL8JK_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HGS1785653.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKDLLGVFLLYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            7971..8614
                     /gene="pcp"
                     /locus_tag="ACL8JK_000733"
                     /pseudo
     CDS             7971..8614
                     /gene="pcp"
                     /locus_tag="ACL8JK_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(8642..9499)
                     /locus_tag="ACL8JK_000734"
     CDS             complement(8642..9499)
                     /locus_tag="ACL8JK_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGS1785654.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9629..10771
                     /gene="tgt"
                     /locus_tag="ACL8JK_000735"
     CDS             9629..10771
                     /gene="tgt"
                     /locus_tag="ACL8JK_000735"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGS1785655.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            10869..12686
                     /locus_tag="ACL8JK_000736"
     CDS             10869..12686
                     /locus_tag="ACL8JK_000736"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGS1785656.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPSYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHRMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            12839..13990
                     /gene="nagA"
                     /locus_tag="ACL8JK_000737"
     CDS             12839..13990
                     /gene="nagA"
                     /locus_tag="ACL8JK_000737"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGS1785657.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14153..15211
                     /locus_tag="ACL8JK_000738"
     CDS             14153..15211
                     /locus_tag="ACL8JK_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HGS1785658.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15362..15727
                     /locus_tag="ACL8JK_000739"
     CDS             15362..15727
                     /locus_tag="ACL8JK_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGS1785659.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            15803..16744
                     /gene="comGA"
                     /locus_tag="ACL8JK_000740"
     CDS             15803..16744
                     /gene="comGA"
                     /locus_tag="ACL8JK_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGS1785660.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            16692..17708
                     /gene="comGB"
                     /locus_tag="ACL8JK_000741"
     CDS             16692..17708
                     /gene="comGB"
                     /locus_tag="ACL8JK_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGS1785661.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            17710..18036
                     /gene="comGC"
                     /locus_tag="ACL8JK_000742"
     CDS             17710..18036
                     /gene="comGC"
                     /locus_tag="ACL8JK_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HGS1785662.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQADGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            18029..18433
                     /gene="comGD"
                     /locus_tag="ACL8JK_000743"
     CDS             18029..18433
                     /gene="comGD"
                     /locus_tag="ACL8JK_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGS1785663.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18396..18698
                     /gene="comGE"
                     /locus_tag="ACL8JK_000744"
     CDS             18396..18698
                     /gene="comGE"
                     /locus_tag="ACL8JK_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HGS1785664.1"
                     /translation="MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQE
                     EAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFSSEKGLEVYHGSEQLLAIKEL"
     gene            18661..19122
                     /gene="comGF"
                     /locus_tag="ACL8JK_000745"
     CDS             18661..19122
                     /gene="comGF"
                     /locus_tag="ACL8JK_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGS1785665.1"
                     /translation="MVQNSCWQSKSYKVKAFTLLESLLALLVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVRFHFQFQKGLEREFIYRVEKEES"
     gene            19100..19513
                     /gene="comGG"
                     /locus_tag="ACL8JK_000746"
     CDS             19100..19513
                     /gene="comGG"
                     /locus_tag="ACL8JK_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGS1785666.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            19650..20237
                     /locus_tag="ACL8JK_000747"
                     /pseudo
     CDS             19650..20237
                     /locus_tag="ACL8JK_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            20298..21251
                     /locus_tag="ACL8JK_000748"
     CDS             20298..21251
                     /locus_tag="ACL8JK_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS1785667.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21302..22492
                     /locus_tag="ACL8JK_000749"
     CDS             21302..22492
                     /locus_tag="ACL8JK_000749"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HGS1785668.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHIQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKYIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22493..22624
                     /locus_tag="ACL8JK_000750"
     CDS             22493..22624
                     /locus_tag="ACL8JK_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785669.1"
                     /translation="MKLKKYSIQGVGKVIFPASFSDEIVQNLAMIGFFEKYGIIVVI"
     gene            22641..23012
                     /gene="rnpA"
                     /locus_tag="ACL8JK_000751"
     CDS             22641..23012
                     /gene="rnpA"
                     /locus_tag="ACL8JK_000751"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGS1785670.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            22987..23811
                     /locus_tag="ACL8JK_000752"
     CDS             22987..23811
                     /locus_tag="ACL8JK_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGS1785671.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            23830..24816
                     /gene="jag"
                     /locus_tag="ACL8JK_000753"
     CDS             23830..24816
                     /gene="jag"
                     /locus_tag="ACL8JK_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGS1785672.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            24867..25490
                     /locus_tag="ACL8JK_000754"
     CDS             24867..25490
                     /locus_tag="ACL8JK_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HGS1785673.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEARKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            25621..27078
                     /locus_tag="ACL8JK_000755"
     CDS             25621..27078
                     /locus_tag="ACL8JK_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS1785674.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27101..27382
                     /locus_tag="ACL8JK_000756"
     CDS             27101..27382
                     /locus_tag="ACL8JK_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1785675.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27459..27944
                     /locus_tag="ACL8JK_000757"
     CDS             27459..27944
                     /locus_tag="ACL8JK_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1785676.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELDDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            27961..28626
                     /locus_tag="ACL8JK_000758"
     CDS             27961..28626
                     /locus_tag="ACL8JK_000758"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGS1785677.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            28630..29493
                     /locus_tag="ACL8JK_000759"
     CDS             28630..29493
                     /locus_tag="ACL8JK_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGS1785678.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SRGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29495..30199
                     /locus_tag="ACL8JK_000760"
     CDS             29495..30199
                     /locus_tag="ACL8JK_000760"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGS1785679.1"
                     /translation="MNQVINAMRKRVCAANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVEPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30376..32049
                     /locus_tag="ACL8JK_000761"
     CDS             30376..32049
                     /locus_tag="ACL8JK_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS1785680.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QNFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32161..33252
                     /gene="ulaG"
                     /locus_tag="ACL8JK_000762"
     CDS             32161..33252
                     /gene="ulaG"
                     /locus_tag="ACL8JK_000762"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGS1785681.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33366..35342
                     /gene="tkt"
                     /locus_tag="ACL8JK_000763"
     CDS             33366..35342
                     /gene="tkt"
                     /locus_tag="ACL8JK_000763"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGS1785682.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAEYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVISMPSTDVFDKQNAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35459..35758
                     /gene="yajC"
                     /locus_tag="ACL8JK_000764"
     CDS             35459..35758
                     /gene="yajC"
                     /locus_tag="ACL8JK_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGS1785683.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            35805..36233
                     /locus_tag="ACL8JK_000765"
     CDS             35805..36233
                     /locus_tag="ACL8JK_000765"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGS1785684.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36235..36645
                     /locus_tag="ACL8JK_000766"
     CDS             36235..36645
                     /locus_tag="ACL8JK_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HGS1785685.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            36945..39596
                     /gene="adhE"
                     /locus_tag="ACL8JK_000767"
                     /gene_synonym="adhC"
     CDS             36945..39596
                     /gene="adhE"
                     /locus_tag="ACL8JK_000767"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGS1785686.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKTRQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARILGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(40582..40890)
                     /locus_tag="ACL8JK_000768"
     CDS             complement(40582..40890)
                     /locus_tag="ACL8JK_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS1785687.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(40887..41195)
                     /locus_tag="ACL8JK_000769"
     CDS             complement(40887..41195)
                     /locus_tag="ACL8JK_000769"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1785688.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(41200..42495)
                     /locus_tag="ACL8JK_000770"
     CDS             complement(41200..42495)
                     /locus_tag="ACL8JK_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGS1785689.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(42513..43922)
                     /locus_tag="ACL8JK_000771"
     CDS             complement(42513..43922)
                     /locus_tag="ACL8JK_000771"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGS1785690.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            44080..44808
                     /locus_tag="ACL8JK_000772"
     CDS             44080..44808
                     /locus_tag="ACL8JK_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS1785691.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            45268..45462
                     /locus_tag="ACL8JK_000773"
     CDS             45268..45462
                     /locus_tag="ACL8JK_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS1785692.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(45568..45737)
                     /locus_tag="ACL8JK_000774"
                     /pseudo
     CDS             complement(45568..45737)
                     /locus_tag="ACL8JK_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(45815..47125)
                     /locus_tag="ACL8JK_000775"
     CDS             complement(45815..47125)
                     /locus_tag="ACL8JK_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HGS1785693.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            47362..48234
                     /gene="nadC"
                     /locus_tag="ACL8JK_000776"
     CDS             47362..48234
                     /gene="nadC"
                     /locus_tag="ACL8JK_000776"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HGS1785694.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT        14784 a         8606 c        10559 g        14402 t
ORIGIN      
        1 tatattttgg aagggtagcg aagaggctaa acgcggcgga ctgtaaatcc gctccttcgg
       61 gttcgggggt tcgaatccct ccccttccat tttacgggca tagtttaaag gtagaactaa
      121 ggtctccaaa accttcagtg tgggttcaat tcctactgcc cgtgttaata gaattatggc
      181 gggtgtggtg aagtggttaa cacaccagat tgtggctctg gcatgcgtgg gttcgatccc
      241 catcactcgc ctattttata ttggggtata gccaagcggt aaggcaaggg actttgactc
      301 cctcatgcgt tggttcgaat ccagctaccc cagttactat ttgccggcgt ggcggaattg
      361 gcagacgcgc tggactcaaa atccagtgtc cgcaaggacg tgccggttcg accccggccg
      421 ccggtatagt atagtgttag gaacgttgtt attcttcgtt ccttttttat attatttttg
      481 gtataattat agttattcaa attttattta gattaagaaa gtgtagggga gtatgtcttg
      541 ttctatcgat ttattaaaac atcggtattt gaaaaatatt aaagaaaatc ctgaattgtt
      601 tgtcggaatt gagttggagt atcctgttgc aagtttagaa ggggatgcta cagatgttga
      661 agttatgaag gatctatttc attatttagt ttctactttg gatctcaccg tagcaaaggt
      721 agatgatttt ggcaatctga tccagttagt agatccgata agtcaggatg ctattttatt
      781 tgaagtttcc tatacaacga ttgagtttgc atttggtaag gctgaaacga ttcaagaggt
      841 cgaaaatcgt ttcaataatt atatgaatgt aattcagaga aagttagctg aatcaaatca
      901 tgctattgtt ggctgtggta tccatcccaa ctgggataaa aatgagaatt gtccagtggc
      961 ttatccacgc tatcagatgt tgatggatta tttgaatttg agtagaaata ttattaaatc
     1021 agatttacat catttccctg aatatggtac ttttatctgt gggagccagg ttcagctgga
     1081 tatttcaaaa accaactact tacgggtgat taatgctttt actcaaattg aagcggctaa
     1141 ggcttattta tttgcaaact ctgaattttc gggtgcggat tgggatacga aaatttcaag
     1201 ggatattttc tgggaagaat ctatgcatgg tatctatcca gagaatgttg gggtcaatgc
     1261 tagactcctt aatgatgaaa ctgatttttt tgactatcta aatcattctg cgatttttac
     1321 tgcggaacgt gatgggcaga cctattattt ttatcctatt caggctgggg actatttggc
     1381 tacgtccgaa atccaagcat ttgctctgaa tggggatgag gttattattt acccccaaga
     1441 gaaggatttt gaaactcatc gtagttacca gtaccaagat ttaacgactc gaggaacagt
     1501 tgagtttcgt agtgtgtgta cacagccact tgataggact tttgcttctg cagcttttca
     1561 cttgggatta ttggttaatt tagacaagtt agaagcttac ttagaaacag cacctttctt
     1621 taaagtattt ggttatgatt acaagtcttt aaggagacaa ttttctaaga aaaatcttac
     1681 agatgaggaa gaaactacga ttattgaatt ttccaaagac ttactcctac tagctgagga
     1741 gggactagtg gtgagaaata aggaagaaat gacctattta cagcctttga gagaagaatt
     1801 gagcctataa tttctcttat aaagggagaa ttttctgaaa aatcatgata taatggacga
     1861 gactatagat aaaggataga gagtaatgac attagtttat caatcaacgc gtgatgccaa
     1921 caatacagta actgccagcc aagcaatttt gcaaggtttg gcgacggacg gcggtttgtt
     1981 tacaccggat acttatccaa aggtagattt gaactttgac aaattgaaag atgcttctta
     2041 ccaggaagtt gctaagctag ttttgtcagc atttttagat gactttacag ttgaggagtt
     2101 ggactactgt atcaacaatg cctacgatag caaatttgat actccagcta ttgcaccatt
     2161 agtgaaatta gatgggcaat acaatttgga acttttccat ggttcaacga ttgcctttaa
     2221 ggatatggcc ttgtctattt tgccatactt tatgacgact gctgctaaga aacatggttt
     2281 ggagaacaag attgttatct tgacagcgac atctggtgac acggggaaag ctgctatggc
     2341 ggggtttgcg gatgtgcctg gtactgagat tatcgtcttt tatccaaagg gtggtgtcag
     2401 caaggtacaa gagttgcaaa tgaccactca gaatggtgac aatactcatg ttatcgctat
     2461 agatggtaac tttgacgatg cgcaaaccaa cgtgaagcac atgtttaacg acgtggctct
     2521 tcgtgaaaga ttagcggcca acaagttgca attttcatct gctaactcta tgaacattgg
     2581 tcgtctggta ccacagattg tttattatgt ttatgcctac gctcagttgg tcaagactgg
     2641 tgagattgtg gctggcgata aggtcaactt cacagtacca acaggaaact ttggaaatat
     2701 cttggctgcc ttttatgcca aacaaatcgg tctcccagtt ggtaaattga tctgtgcttc
     2761 aaatgacaac aatgttttga cagacttctt caagacacgt gtttacgaca agaaacgtga
     2821 gtttaaggta acaaccagcc catctatgga tatcttggta tcttcaaact tggagcgttt
     2881 gattttccat cttttgggga atgatgcggt taagacggct aaactcatga atgctttgaa
     2941 tagccaaggt caatatgagt tgactaattt tgatgcagag attttggacc tctttgcagc
     3001 tgaatatgcg actgaggaag aaactgcggc agaaatcaag cgtgtttatg agtcagattc
     3061 ttatatcgag gatcctcata cagcggttgc ctcagcagtg tatagaaaat accaatcggc
     3121 cactggagat gtaactaaga cagtgattgc ttcaacagct agtccataca agttcccagt
     3181 agttgcagta gaaactgtaa ctggaaaagc aggtttaaca gactttgaag ccttggctca
     3241 attacatgaa atctcaggcg ttgcagtgcc accagcagtt gatgggcttg aaatagctcc
     3301 aattcgtcac aagacaacag tggcagctgc tgacatgaaa gcagcggttg aggcttattt
     3361 aggactttaa gacagaggga gcaaactcgg ttgggaaacc aactgagttt cttttcatca
     3421 ggaggagaga ttgtttaaga aaaataaaga cattcttaat attgcattgc cagctatggg
     3481 tgaaaacttt ttgcagatgc taatgggaat ggtggacagt tatttggttg ctcatttagg
     3541 attgatagct atttcagggg tttcagtagc tggtaatatt atcaccattt atcaggcgat
     3601 tttcatcgct ctgggagctg ctatttccag tgttatttca aaaagcatag ggcagaaaga
     3661 ccagtcgaag ttggcctatc atgtgactga ggcgttgaag attaccttac tattaagttt
     3721 ccttttagga tttttgtcca tcttcgctgg gaaagagatg ataggacttt tggggacgga
     3781 gagggatgta gctgagagtg gtggactgta tctatctttg gtaggcggat cgattgttct
     3841 cttaggttta atgactagtc tgggagcctt gattcgtgca acgcataatc cacgtctgcc
     3901 tctctatgtt agttttttat ccaatgcctt gaatattctt ttttcaagtc tagctatttt
     3961 tgttctggat atggggatag ctggtgttgc ttgggggaca attctgtctc gtttggttgg
     4021 tcttgtgatt ttgtggtcac aattaaaact gccttatggg aagccaactt ttggtttaga
     4081 taaggaactg ttgaccttgg ctttaccagc agctggagag cgacttatga tgagggctgg
     4141 agatgtagtg atcattgcct tggtcgtttc ttttgggacg gaggcagttg ctgggaatgc
     4201 aatcggagaa gtcttgaccc agtttaacta tatgcctgcc tttggcgtcg ctacggcaac
     4261 ggttatgctg ttggcccgag cagttggaga ggatgattgg aaaagagttg ctagtttgag
     4321 taaacaaacc ttttggcttt ctctgttcct catgttgccc ctgtccttta gtatatatgt
     4381 cttgggtgta ccattaactc atctctatac gactgattct ctagcggtgg aggctagtgt
     4441 tctagtgaca ctgttttcac tacttggaac ccctatgacg acaggaacag tcatctatac
     4501 ggcagtctgg cagggattag gaaatgcacg cctccctttt tatgcgacaa gtataggcat
     4561 gtggtgtatc cgcattggaa caggatatct gctggggatt gtgcttggtt ggggcttgcc
     4621 tggtatttgg gcagggtctc tcttggataa tggttttcgc tggttatttc tacgctatcg
     4681 ttaccagcgc tatatgagct tgaaaggata ggaaatgcaa aaaacagctt ttatttggga
     4741 tttagacggg actttattgg actcttacga agcgatttta tcagggattg aggagacttt
     4801 tgctcagttt tctattcctt atgataagga gaaggtgaga gagtttatct tcaagtattc
     4861 ggtgcaagat ttgcttgtgc gggtggcaga agatagaaat ctggatgttg aggtgctaag
     4921 tcaggtgcgt gcccagagtc tgactgagaa gaatgctcag gtagttttga tgccaggtgc
     4981 gcgtgaggtg ctagcttggg cagacgaatc aggaattcag cagtttatat atactcataa
     5041 ggggaacaac gcttttacca ttctcaagga cttgggggtg gaatcctatt ttacagagat
     5101 tttaaccagt cagagtggct ttgtgcggaa gccaagtcca gaagcggcta cctatctgct
     5161 agataagtat cagttgaatt ctgataatac ttattatata ggggatcgga ctctggatgt
     5221 ggaatttgcc cagaatagtg ggattcaaag tatcaacttt ttagagtcta cttatgaagg
     5281 gaatcacagg attcaagcgt tagcagatat ttcccgtatt tttgagacta agtgataaaa
     5341 agattgtgtc agttttgtga cagagaccta acaaactatt tcaagtaacc tagtttgtta
     5401 caaggaatag acagttctgt taaataggcc cgagagggct ttttttctac attttttgtg
     5461 ttatcataga caggtactca tttgaaagga atttgaaaga atgaagaaaa gaatgttatt
     5521 agcgtcaaca gtagccttgt catttgcccc agtattggca actcaagcag aagaagttct
     5581 ttggactgca cgtagtgttg agcaaatcca aaacgatttg actaaaacgg acaacaaaac
     5641 aagttatacc gtacagtatg gtgatacttt gagcaccatt gcagaagcct tgggtgtaga
     5701 tgtcacagtg cttgcgaatc tgaacaaaat cactaatatg gacttgattt tcccagaaac
     5761 tgttttgaca acgactgtca atgaagcaga agaagtaaca gaagttgaaa tccaaacacc
     5821 tcaagcagac tctagtgaag aagtgacaac tgcgacagca gatttgacca ctaatcaagt
     5881 gaccgttgat gatcaaactg ttcaggttgc agacctttct caaccaattg cagaagctcc
     5941 aaaagaagta gcatcaagtt cagaagttac aaagacagtg attgcttctg aagaagtggc
     6001 accatctacg ggcacttctg tcccagagga gcaaacggcc gaaacaactc gcccagttga
     6061 agaagcaact cctcaggaaa cgactccagc tgagaagcag gaaacacaag caagccctca
     6121 agctgcatca gcagtggaag taactacaac aagttcagaa gcaaaagaag tagcatcatc
     6181 aaatggagct acagcagcag tttctactta tcaaccagaa gagacgaaaa caatttcaac
     6241 aacttacgag gctccagctg cgcccgatta tgctggactg gcagtagcga aatctgaaaa
     6301 tgcaggtctt caaccacaaa cagctgcctt taaagaagaa attgctaact tgtttggcat
     6361 tacatccttt agtggttatc gtccaggaga cagtggagat cacggaaaag gtttggctat
     6421 cgactttatg gtaccagaaa gttcagaatt aggggataag attgcggaat atgctattca
     6481 aaacatggcc agccgtggca ttagttacat catctggaaa caacgtttct atgctccatt
     6541 cgatagcaaa tatgggccag ctaacacttg gaacccaatg ccagaccgtg gtagtgtgac
     6601 agaaaatcac tatgaccacg ttcacgtttc aatgaatgga taaacccgac ttggtaacat
     6661 cattttgacg aatgagatct agctttcgtg ataggaagcg attctcgttc gttttttctt
     6721 tgtcatactc ttcgaaaatc tcttcaaaca acgtcagttt tatctgaaac ctcaaagctg
     6781 tgctttgagc aacctgcgac tagcttccta gtttgctttt tgattttcat tgagtatcaa
     6841 tttgaatgga aaatggaaag ttatcatctt gtaatgagtt aagcaacatt cttgcaatct
     6901 attttatagt agattgaaac tagaatagta cacaactgct tctaaaacat tgttagaaat
     6961 cgatttgact gtcctgatcg atttgtcctg ctcttatttc atttcactat actttatatt
     7021 ataattgact ggtcaaatat tgataaatca ataaaaagag aggggaagaa atgctagaga
     7081 ttcaagattt actgtatcaa ctccgcttgt ctgagcaagt gagtacgcaa ttgtttgaaa
     7141 aagcttggga ttagtttgac acggtatcag attttactgt ttttgctgga gcattctctt
     7201 tgtaaccaaa tggcggttca ggagcgtttg aaaattgatc aggctgcttt gacacggcat
     7261 ttcaagattt tggaaacgga aggtttggtg gagcgtcatc gtaatcctga aaatcagcgg
     7321 gaagtgttgg tagaggctgc gaagtatgcc aaggagcagt tagtggtgaa tccccctctg
     7381 caacatatca aggttaagga agagatggaa agtatcttaa cagagtttga gagaacagaa
     7441 ctcagccgtt tattaaataa attggttttg ggtattgaaa atatagaaat ttaaggagaa
     7501 atagatgtca attattttaa caacgatcgt tgctttggag catttttaca ttttttattt
     7561 ggaaagtatt gccacgcaat cagatgcgac tagtcgtgta tttaatatgg aaaaggaaga
     7621 attggctcat ccgtcagtaa gttcattgtt caaaaatcaa ggaatttata aggatctgct
     7681 aggagtcttt ctcttgtatg gcatttattt ctcacagaat ttagaaattg tgactatttt
     7741 tgtcttattt gtgattggtg ctgcgactta cggctcttta acagcggata aaaaaattat
     7801 tttgaaacaa ggtggatcag ctattttggc cttgattagt attttactct ttaaatacac
     7861 ttgaaggtcg attctaatct cgctaatcct tttcaatcca gaataaggga aatatgttat
     7921 acttgttttt aagaaaaaag tctcattgaa ttggttttga ggagttagaa atgaaagtat
     7981 tagtgacagg ttttgagccc tttggagggg aaaagggcaa tccagctttg gaggccatta
     8041 aaggtttacc agctgaaatc catggtgctg aggtccgttg gctagaggtg ccgacagttc
     8101 ttcacaaatc tgctcaagta ttggaagaag agatgaatcg ttatcaacct gactttgtcc
     8161 tttgtattgg gcaagctggt ggaagaacta gtttgacacc tgaacgagtg gccattaatc
     8221 aagacgatgc acgtacttct gataacgaag ataatcaacc gattgaccgt cccattcgcc
     8281 cagatggtgc ttcggcctac tttagtagtt tgccgattaa agcgatggtt caagctataa
     8341 aaaagaagga ttgccggcct ctgtttccaa tacggcaggg acttttgtct gcagccattt
     8401 gatgtatcag gctctctatt tggtagaaaa gaaatttcca tatgttaagg caggttttat
     8461 gcatattcct tatatgatgg aacaggtggt gaacagaccg cctattccag ctatgagttt
     8521 agtggatatt cggcgaggga tagaagcagc aatcggcgct atgatagaac atggagatca
     8581 ggaactcaag ttggtaggcg gagaaactca ttgatagaaa aaagcttgag gggaaaaacc
     8641 ttcaagcttt tggacgtttt cgagccaata ctgctcggta aaacataatt ttagtgcatt
     8701 ggatataagg taggagtgaa aaactagcaa tgccaaaggt aatccaattg aggaagtacc
     8761 aaggaagaag ctgtaaatct aggacaaagt gctggaactt gtagcccttc ataaaggaac
     8821 ggctagtttt taggattcgt cttggtggga cctgtcctag gtctagacta taacagagaa
     8881 gaaattccac ctgtgaatag gcataatact gtggaatata gaggatattc cctacaatga
     8941 tcaagatgag acttgcaaga aagtagagtc caaagaccat gaggaaacgc tcggtttcaa
     9001 ctgatgagag atctagattt ggaaactcag gatgtagggt gacgaatttt ttggctaaaa
     9061 agctactata aaagaggagg taaatcccaa gtaaattagg gatactccat aaaaagagat
     9121 agaaacgttt gagaagtagg gtcaaaaagg tttgagaaaa gcgctcctca tcaaagagag
     9181 ctaggctgtt ttttacagat ggctccgttt tagaatcttt catgagtgtc agtgttgcat
     9241 agacggaact ggtcaaaaga atagtcccga taaaggagac tagtagagga aagaggtagg
     9301 cttgaagtat ttggccaagt atgctgaaaa atggctgttc taaaacagtc ccgtggatcc
     9361 gagataaggg attaagaaaa ctagataaga tgaccagcat actgggaagg atatagagga
     9421 gaaagagacg gggggtgtca gcctgaaaat gttttgactc ctgacgaatt gtttttaaat
     9481 caatttttgg atagttcatt ctcttattat accatagttc ttatacatag ttcgtgacag
     9541 ttcctacttt ttttgataaa atcatacagt gtgtccttgg gcacactgta tgaactggga
     9601 ctgtctttcc cagcttcgga ggtaaaaaat gtcagattca ccaatcaaat atcgtttgat
     9661 taagaaagaa aaacacacag gagctcgtct aggagaaatc atcactcccc acggtacctt
     9721 tccgacacct atgtttatgc cagttgggac acaagccact gtcaaaactc agtcacctga
     9781 agaattgaag gagatgggtt cgggaattat cctatcaaac acctatcatc tctggcttcg
     9841 ccctggagat gaactcattg cacgcgctgg tggtctccac aagttcatga attgggacca
     9901 gcctatcttg acagatagtg gtggttttca ggtttattct ttagcagata gccgtaatat
     9961 cacagaagaa ggagtaacct ttaaaaatca tctaaatggt tctaagatgt tcctatcccc
    10021 agaaaaagcc atctctattc agaataatct gggttcagac atcatgatgt cctttgatga
    10081 atgtcctcag ttttatcaac cttatgacta cgttaagaaa tcgatcgagc gtaccagccg
    10141 ttgggctgag cgtggtttga aggctcaccg tcgtccacat gaccaaggtt tgtttggaat
    10201 tgtgcaaggt gcaggatttg aagaccttcg ccgccaatca gctcatgatc ttgtcagcat
    10261 ggatttctca ggctactcta tcggtggttt ggcagtggga gaaacccatg aagagatgaa
    10321 tgcggtcttg gactttacaa ctcaactgct acctgaaaat aaacctcgtt atctgatggg
    10381 tgtgggagcg ccagatagct tgatcgatgg ggtcattcgt ggggtggata tgtttgactg
    10441 tgtcttaccg actcgaattg ctcgtaacgg gacttgtatg accagtcaag gacgtttggt
    10501 tgtgaaaaat gcccagtttg ctgaggactt tacgccactg gatcctgagt gtgactgcta
    10561 cacatgtaat aactatacac gcgcttacct tcgtcacctg ctcaaggctg atgaaacctt
    10621 tggtatccgc ttgactagct accacaatct ttacttcttg cttaacctga tgaagcaagt
    10681 gcgacaagcc atcatggatg acaatctctt ggaattccgt gagtattttg tggaaaaata
    10741 tggctataat aagtcaggac gtaatttcta aaatggaatt gatataaaaa aatcctaagt
    10801 tttctcttag gatttttctt ctttttttga tagaataaag tgtacaatga aaggaagaat
    10861 aaactcgtat gcgcattaaa tggttttcct tgattaggat tataggttta cttttggtac
    10921 tcttgtatca cttctttcag acgatctttc ctggaggatt tttcggggta gatgtctttt
    10981 tcacattttc aggtttcctg attacagctc tactcattga agaattttct aagaacaatg
    11041 agattgattt gataggattt tttagaagac gcttttatcg gattgtgcca cctgtggttt
    11101 tgatggtctt ggtgaccatg ccttttactt tcttggttcg ccaagactat gttgctggaa
    11161 ttggtggcca gattgcgggc gtcttaggct ttatgaccaa cttctatgaa ctcctaacag
    11221 gtgggagtta tgaatctcag ttcattcctc atttgtttgt tcataattgg agtttggcag
    11281 ttgaggttca ctactatatt ctttggggat tggcagtttg gttcttatcc aaacaagcta
    11341 aatcaaatgg tcagttgaag gggatggtct ttctcttatc tgctgctgcc ttcttgatca
    11401 gtttcttctc catgtttatt ggtagttttc tagtgacctc ttattcctct gtttatttct
    11461 ccagtttaac tcatgtctat ccattctttt tgggaagtat gttagcaact attgtaggcg
    11521 ttcgtcagac gacttccctc gtcaagcagt tggataaaat ctgggattta cgaaagactt
    11581 tggtagtttt tggaggaggc tttggtttcc tagttctttt gactttcttt gtcaaattca
    11641 cttatctttt tgcctatctt atcggcttct tgcttgccag tcttgcagct cttgccatga
    11701 ttctggcggc gcgtgtctta catgaaaaga cacatcatat acaggagccg aagattatca
    11761 gctttttagc ggatactagc tatgcggttt atcttttcca ttggccttcc tatatcattt
    11821 tctcacagtt gacatcaaat cttcttgctg tattactgac tctgatttgt tcttatggct
    11881 ttgccagtct gtcattctat gtattggaac cttggattgc aggcaagaac acacctattt
    11941 tacaaactct tcgtcccctg ccttatattc acgcaattct tgcagcaggt acaggaatct
    12001 tgaccttcat tgtctgcatg gtgaccttgt tggcaccaca agtgggagcg tttgagacag
    12061 acttgactgt taatggcttg aagcaagctg caacaaatat tggccagacc aaggtgatgg
    12121 cagaacgggc agatgcaaac agtttgggaa ttgctgatgg cactatgtta attggtgact
    12181 cagtggcttt aagggcaaat acagcactac agacagctct tcctggagca cagattaacg
    12241 cgcaggtcag cgtaacaacc aagaccgcaa atgaaatcat gctaaataat agccagaata
    12301 aatttttacc taagacggtg gtcattgcga ctggggtaaa taatcctgag aattacaagg
    12361 atgactggga cagtatcgtg aaaaatcttc ctaagggaca ccgtatgatt ttggtgactc
    12421 cttatgaggg agataagaca aaagagacct atgccatcgt tgagaaggct gctgcctata
    12481 tgagagaatt ggcagagaag acaccttaca ttacgatagc agattggaat caagttgcga
    12541 aagagcatcc agaaatttgg gcaggaacag accaggttca tttcgggagt gagagtagca
    12601 ctatcgaagc aggagcaaaa ttgtatgcag atacgattgc cacagctttg cagacagctc
    12661 aagacaagcc ggttaaatca aaataacttg tattaaaaaa gagaagagtt ggagaaatcc
    12721 agctctttta aaatatctcc aaaaaatagg tctataccat ttacaaataa aaaagaaagg
    12781 tttataatgt aattgacata ataaattgta gaatcaatct tttaaggagg ttaacattat
    12841 gcctaactat attaaagcgg atcagttttt ctacccacac ggagttcgtc gaggtggtta
    12901 cttggaactt gtggacggca agtttgggaa acatgtagag cagattcctg aaggggctga
    12961 ggtgattgac tatacaggtt atagcattgc cccaggtctt gtggatactc atattcatgg
    13021 atatgcaggt gtagatgtga tggacaacaa cattgaaggt acattgcata ctatgagtga
    13081 aggacttctt agtaccggtg ttaccagttt cttacccaca actttaacag ccacttatga
    13141 gcaattgctt gcagtcactg aaaatcttgg aaaccattat aaagaagcaa caggtgctaa
    13201 gattcgtggg atttattatg aaggtccata tttcacagaa acttttaagg gggcacaaaa
    13261 tccaacttat atgagagacc cgggtgttga ggagtttcat tcttggcaaa aagcggcaaa
    13321 tggcttgctt aataaaattg cccttgcacc agaacgtgat ggggtggaag actttgttcg
    13381 tacagttacg ggcgaaggtg tgacggttgc tcttggacat tcaaacgcga cttttgatga
    13441 agccaaaaaa gcagtcgatg ctggagcgag tgtttgggtg catgcctaca atggaatgcg
    13501 tgggttgact caccgtgaat tgggtatggt tggagccatg taccaattgc cacataccta
    13561 tgcagagttg atctgtgatg gtcaccacgt agatccaaag gcttgcgaaa ttcttatcaa
    13621 acaaaaagga acagaaaaca tcgctcttat cacagactgt atgacagctg ggggattgga
    13681 agacggagat tatatgttgg gagaattccc agttgtcgtt gcaaatggaa ctgcacgcct
    13741 caaatcgaca ggtaacttgg caggttctat cctcaaactc aaagatggtt tgaagaatgt
    13801 ggtcgaatgg ggaattgcga atccgcatga agcagtcatg atggccagct tcaacccagc
    13861 taaatccgtt cacatcgatg acgtctgtgg ccaaatccgt gaaggctacg acgctgactt
    13921 catcgtatta gataaagatt tggaattggt agcaacctac ctagatggtg tgaaacgtta
    13981 tcaagcataa gagagaaggc agaagttaga gactagcttc tgctttttta tacagggtac
    14041 tttactggta aataaaaagt taaaaaaatc acaaaaaaag cttgaagaaa caaagaaaaa
    14101 ggcttacaat tgaactataa atattacaaa taaaaaaacg gaggagtgct ttatgaaagc
    14161 ctatacttat gttaaaccag gacttgcttc ttttgttgat gtagacaaac cagttattcg
    14221 caagccaaca gacgctattg tgcgtattgt aaaaaccact atttgtggaa cagacctcca
    14281 tattatcaaa ggggatgttc ctacttgcca aagtggtacc attcttggcc acgaagggat
    14341 tgggattgtt gaagaagttg gggaaggagt ttccaacttc aaaaaaggtg acaaggtctt
    14401 gatttcttgc gtctgtgcct gtggtaaatg ctactactgt aaaaaaggaa tttatgccca
    14461 ctgtgaagac gaagggggct ggattttcgg tcacttgatt gatggtatgc aggctgaata
    14521 tctacgtgtc cctcatgcag ataatactct ttaccatact ccagaagact tgtcagatga
    14581 agctttggtt atgctgtcag acattctgcc tactggatat gaaattggtg tcttaaaagg
    14641 gaaagtagaa cctggttgca gcgtagccat tattggttca ggtccagttg gattggctgc
    14701 tcttttaaca gcccaattct attcaccagc taaattgatt atggtagacc tagacgataa
    14761 ccgcttggaa actgccctat cattcggtgc gactcataag gttaattctt cagaccctaa
    14821 aaaagccatt aaagaaattt atgatttgac agatggtcgt ggtgtggatg tcgctatcga
    14881 agctgtaggg attcctgaaa catttgattt ctgtcaaaag attatcggtg tagacggaac
    14941 ggttgccaac tgtggtgtgc atggtaaacc agttgaattc gatttagata aactttggat
    15001 tcgcaacatc aatgtaacaa ctggtttggt atctacaaat acgactccac aattgttgaa
    15061 agcacttgaa agtcataaga ttgaaccgga aaaattggta actcactatt tcaaactcag
    15121 tgaaattgaa aaagcctacg aagtcttcag taaggcagca gaccaccatg ccattaaggt
    15181 cattatcgaa aacgatatct cagaagccta agtagtaaaa atatttttgt acataagcaa
    15241 atagaaattc agtcatccat cagatggctg gattttttat caaaaaatta agaaatgagc
    15301 atatttcttt ccttgtctgg cggaattggt tataatatac ggtacaaagg aatgaatgaa
    15361 tatgtatcgt gttatagaaa tgtacggaga ttttgaaccg tggtggttct tagaaggttg
    15421 ggaagaagat attgtagcaa gtagaaaatt tgaccagtat tatgatgctc tcaaatacta
    15481 caaaacttgc tggtttagat tggaacaaga atcccctctt tataaaagta gaagcgactt
    15541 gatgaccatt ttttgggacc cggaagacca acgctggtgt gatgaatgtg atgagtattt
    15601 acaacaatac cattctttgg ctcttttgca ggatgagcag gttatcccag acgaaaaact
    15661 acgctcaggc tatgaaaaac aaaccagtca ggaaaggaat cgttcttgcc gtatgaaatt
    15721 aaaatagaga aaagtaactt ttttggagtt gcttttttta tttttctaac tctttgcgaa
    15781 tagtataggt gaggaggtaa gtatggttca agaaattgca caagaaatca ttcgttcagc
    15841 tcggaaaaaa gggacgcagg atatttattt tgtccctaag ttagatgcct atgagcttca
    15901 tatgagggta ggagacgagc gctgtaaaat tggtagctat gattttgaaa agtttgcagc
    15961 cgttatcagt cactttaagt ttgtggcggg tatgaatgtg ggagaaaaaa gacgtagtca
    16021 actgggttcc tgtgattatg cctatgacca gaagatagcg tctctacgtt tatctactgt
    16081 aggcgattat cgggggcatg agagtttggt tatccgtttg ttgcacgatg aggagcagga
    16141 cttgcatttt tggtttcagg atattgaaga attaggcaag cagtacaggc aacggggact
    16201 ctatcttttt gctggtccgg ttgggagtgg taagacgacc ttgatgcatg aattgtccaa
    16261 gtcactcttt aaaggacagc aagttatgtc catcgaagat cctgtcgaaa tcaagcagga
    16321 cgacatgctt cagttgcagt tgaacgaagc aatcggccta acctatgaaa atctaatcaa
    16381 actttccttg cgtcatcgac cagatctctt gattatcgga gaaattcgtg acagcgagac
    16441 ggcgcgtgca gtggtcagag ctagtttgac aggtgcgaca gtcttttcaa ccattcacgc
    16501 caagagtatc cgaggtgttt atgagcgtct gctggagttg ggtgtgagtg aagaagaatt
    16561 ggcagttgtt ctgcaaggag tctgctacca gagattaatc gggggaggag gaatcgttga
    16621 ctttgcaaac agagattatc aagaacacca agcagccaag tggaatgagc aaattgacca
    16681 gcttcttaaa gatggacata tcacaagtct tcaggctgag acggaaaaaa ttagctacag
    16741 ctaagcaaaa aaatatcatc accctattta acaatctctt ttctagcggt tttcatctgg
    16801 tggagactat ctccttttta gataggagtt ccttgttgga caagcagtgt gtgacccaga
    16861 tgcgtacagg cttgtctcag gggaaatcat tctcagaaat gatggaaagt ttgggatgtt
    16921 caagtaccat tgtcactcag ttatctctag ctgaagttca tggcaatctt cacctgagtt
    16981 tgggaaagat agaagaatat ctagacaatc tggccaaggt caagaaaaag ttaattgaag
    17041 tagcgaccta tcctttgatt ttgctgggtt ttcttctctt aattatgctg gggctacgga
    17101 attacctgct cccacaactg gatagtagca atattgccac ccgaattatc ggtaatctgc
    17161 cacaaatttt tctaggcatg gtagggcttg tttccgtgct tgccctttta gcactaactt
    17221 tttataaaag aagttctaag atgagtgtct tttctatctt agcacgcctt ccctttattg
    17281 gaatctttgt gcagacctac ttgacagcct attatgcacg tgaatggggg aatatgattt
    17341 cacagggaat ggagctgacg cagatttttc aaatgatgca ggaacaaggt tcccagctct
    17401 ttaaagaaat cggtcaagat ctggctcaaa ccctgaaaaa tggccgtgaa ttttctcaga
    17461 cgataggaac ctatcctttc tttaggaagg aattgagtct catcatagag tatggggaag
    17521 ttaagtccaa gctgggtagt gagttggaaa tctatgctga aaaaacttgg gaagcctttt
    17581 ttacccgagt caaccgcacc atgaatttgg tgcagccact ggtttttatc tttgtggcac
    17641 tgattatcgt tttactttat gcggcaatgc tcatgcccat gtatcaaaat atggaggtaa
    17701 atttttaaaa tgaaaaaaat gatgacattc ttgaaaaaag ctaaggttaa agcttttaca
    17761 ttggtggaga tgttagtagt cttgctgatt atcagcgtgc ttttcttgct ctttgtacct
    17821 aatctgacca agcaaaaaga agcagtcaat gacaaaggaa aagcagctgt tgttaaggtg
    17881 gtggaaagcc aggcagaact ttatagctta gaaaagaatg aagatgctag cctaagaaag
    17941 ttacaagcag atgggcgcat cacggaagaa caggttaaag cttataatga atactatact
    18001 aaaaatggag gggcaaatcg taaagtcaat gattaaggcc tttaccatgc tggaaagtct
    18061 cttggttttg ggacttgtga gtatccttgc cttgggctta tccggctctg tccagtccac
    18121 ttttgcagca gtagaggagc agattttctt tatggagttt gaagaactct atcgggaaac
    18181 ccaaaaacgc agtgtagcca gtcagcaaaa gactagtcta aatttagatg ggcagacgct
    18241 tagcaatggc agtcaaaagt tgacagttcc taaaggaatt caggcaccat caggccaaag
    18301 tattacattt gaccgagctg ggggcaattc gtccctggct aaggttgaat ttcagaccag
    18361 taaaggagcg attcgctatc aattatatct aggaaatgga aaaattaaac gcattaagga
    18421 aacaaaaaat tagggcagtg attttactgg aagcagtagt cgctctagct atctttgcca
    18481 gcattgcgac cctccttttg ggacaaattc aaaaaaatag gcaagaggaa gcaaaaatct
    18541 tgcaaaagga agaagtcttg agggtagcta agatggcctt gcagacaggt caaaatcagg
    18601 taaacataaa cggagttgag attcaggtgt tttctagcga aaagggattg gaggtctacc
    18661 atggttcaga acagttgttg gcaatcaaag agctataagg tcaaggcttt taccttgtta
    18721 gaatccctgc ttgccctgct tgtcatcagt gggggcttac tcctttttca agctatgagt
    18781 cagctcctca tttcagaagt tcgctaccag caacaaagcg agcaaaagga gtggctcttg
    18841 tttgtggacc aacttgaggt agaattagac cgttcgcagt tcgaaaaagt agaaggcaat
    18901 cgcctataca tgaagcaaga tggcaaggac atcgccatcg gtaagtcaaa gtcagacgat
    18961 tttcgtaaaa ccgatgctag tggacggggg tatcagccta tggtttatgg cctcaaatca
    19021 gctcagatta cagaagacaa tcaactggtt cgctttcatt tccagtttca aaaaggctta
    19081 gaaagggagt tcatctatcg tgtggaaaaa gaagaaagtt aaggcaggtg ttctcctcta
    19141 tgcagtcacc atggcagcta tctttagtct tttgttgcaa ttttatttga accgacaaat
    19201 cgcccactat caagactatg ctttaaataa agaaaaattg gttgcttttg ccatggctaa
    19261 acgaaccaag gataaagccg agcaagaaag tggggaacag gtctttaatc taggtcaggt
    19321 aagctatcaa aacaagaaaa caagcttggt gacgactgtt cgtacgtcta agagccaata
    19381 tgagtttctg tttccttcag tcaaaatcaa agaagagaaa agagataaaa aggaagaggt
    19441 agcgaccgat tcaagcgaaa aagtggagaa gaaaaaatca gaagagaagc ctgaaaagaa
    19501 agagaattcc tagtcaattc aactataatg cgttgaatcc agaatagtcc actgtagttt
    19561 ctagaaaatt gctggaaatg gatgttaagc tccaattcat ttgtttatat cttatttcag
    19621 tttactatac tttgtgctaa actaaagata tgaaacatga ttttaaccac aaagcagaaa
    19681 ctttcgactc ccctaaaaat atcttcctcg caaacttggt atgtcaagca gtcgagaaac
    19741 agattgatat tttatcagac aaagtaattt tagatttcgg tggtggcacg ggtctattag
    19801 ccttgcccct agccaagcag gctaagtcag ttactcttgt agacatttct gagaaaatgt
    19861 tggagtaagc tcgtttgaaa gcggagcagc aagcaatcaa gaatatccag tttttggagc
    19921 aagatttacc gaaaaatccc ttggagaaag agtttgattg ccttgctgtt agtcgggttc
    19981 ttcatcatat gcctgatttg gatgcggatc tctcactgtt tcatcaacat ttgaaggaag
    20041 atgggaaact catcattgct gattttacca agacagaagc taatcatcat ggatttgatt
    20101 tagctgaact ggaaaacaag ctaattgagc atggtttttc atctgtgcat agtcagattc
    20161 tctatagcgc tgaagacctg tttcaaggga atcactcaga attcttttta acagtatccc
    20221 aaaaatcact cgcctagtca gggagtgatt tttctataag gatggaaaaa agaagggaaa
    20281 tttgataaga taggaatatg gattttgaaa aaattgaaca agcttatatc tatttactag
    20341 agaatgtcca agtcatccaa agtgatttgg cgaccaactt ttatgacgcc ttggtggagc
    20401 aaaatagcat ctatctggat ggtgaaactg agctaaacca ggtcaaagac aacaatcagg
    20461 cccttaagcg tttagcacta cgcaaagaag aatggctcaa gacctaccag tttctcttga
    20521 tgaaggctgg gcaaacagaa cccttgcagg ccaatcacca gtttacaccg gatgctattg
    20581 ctttgctttt ggtgtttatt gtggaagagt tgtttaaaga ggaggaaatt actatcctcg
    20641 aaatgggttc tgggatggga attctaggcg ctactttctt gacctcgctt gataaaaagg
    20701 tggattactt gggaatggaa gtggatgatt tgctgattga tctggcagct agcatggcag
    20761 atgtaattgg tttgcaggct ggctttgtcc aaggagatgc cgttcgtcca caaatgctca
    20821 aagaaagcga tgtggtcatc agtgacttgc ctgtcggcta ttatcctgat gacgccgttg
    20881 cgtcgcgcca tcaagttgct tctagccaag aacatactta cgcccatcac ttgctcatgg
    20941 aacaagggct taagtacctc aagtcagacg gatacgctat ttttctagct ccgagtgatt
    21001 tgttgaccag tcctcaaagt gatttgttaa aagaatggct gaaagaagag gcgagtctgg
    21061 ttgctatgat tagtctgcct gaaaatctct ttgctaatgc taaacaatct aagactattt
    21121 ttatcctaca gaagaaaagt gaaatagcag tggagccttt tgtttatcca cttgctagct
    21181 tgcaagatgc aagtgtttta atgaaattta aagaaaattt tcaaaaatgg actcaaggta
    21241 ctgaaatata aaatagattt tgttataata gttgaaaacg cttaaaaagg ggtatcatat
    21301 tatgacaaaa acaattgcaa tcaatgcagg aagttcaagt ttgaaatggc aattatactt
    21361 aatgccagaa gaaaaagtat tggcgaaagg tttgattgaa cgtatcggtt tgaaagattc
    21421 aatttcaact gtaaaatttg acggccgttc tgaacaacaa attttggata ttgaaaatca
    21481 tatacaagcc gttaaaattt tattggatga cttgattcgt ttcgatatta tcaaggctta
    21541 tgacgagatt acaggtgttg gacatcgtgt tgttgctggt ggagaatatt tcaaagaatc
    21601 aacagttgtt gagggagatg ttttagaaaa agttgaagag ttgagtttgt tggctcctct
    21661 acacaacccg gccaatgcag caggtgttcg tgccttcaag gaattgttgc cagacattac
    21721 cagtgtagtt gtttttgata cttccttcca cacaagtatg ccagagaaag cttatcgtta
    21781 ccctctacca acaaaatatt acacagaaaa caaggttcgt aaatacggtg ctcatggtac
    21841 aagtcaccag tttgtagcag gagaagctgc aaaactcttg ggacgtccat tagaagactt
    21901 gaagttaatt acctgtcata ttggtaacgg aggctcaatt acagctgtga aagccggcaa
    21961 atctgtagac acttctatgg ggttcactcc tcttggtggt attatgatgg gaacgcgtac
    22021 aggggatatt gatccagcta tcattcctta tttaatgcaa tatacagagg attttaacac
    22081 accagaagat atcagtcgtg ttcttaaccg tgaatcaggt cttttgggag tttctgctaa
    22141 ttctagcgat atgcgcgata tagaagcagc tgtagcagaa gggaatcacg aggctagctt
    22201 ggcttatgaa atgtatgttg accgtatcca aaaatatatc ggtcagtacc ttgcagtgct
    22261 aaatggagca gatgccattg ttttcacagc aggtgtcggt gaaaatgcag agaatttccg
    22321 tcgtgatgta atctcaggga tttcgtggtt tggttgtgat gttgatgatg aaaagaatgt
    22381 ctttggcgtt acaggagaca tctcaacaga ggcagctaaa atccgtgtct tggttattcc
    22441 aacagatgaa gaattagtca ttgcccgtga cgttgaacgc ttgaaaaaat aagtgaaact
    22501 aaaaaaatat tcaatacaag gagttgggaa agttattttt ccagcttctt tttctgatga
    22561 aattgtccaa aaccttgcta tgattggctt ttttgaaaaa tatggtataa tagtagtaat
    22621 ttaatagatg gagttgagtt ttgaagaaaa actttcgtgt aaaaagagag aaagatttta
    22681 aggcgatttt caaggagggg acaagttttg ctaatcgcaa atttgtggtc taccaattag
    22741 aaaaccagaa aaaccatttt cgagtaggtc tatcagttag caaaaaactg gggaatgccg
    22801 tcactagaaa tcaaattaag cgacggattc ggcatattat ccagaatgca aaagggagtc
    22861 tggtagaaga tgtcgacttt gttgtcattg ctcgaaaagg agtcgaaacc ttgggatacg
    22921 cagagatgga gaaaaatcta ctccatgtat taaaattatc aaagatttac cgggaaggaa
    22981 atgggagtga aaaagaaact aaagttgact agtttgctag gactgtctct gttaatcatg
    23041 acagcctgtg cgactaatgg ggtaactagc gatattacag ccgaatcggc tgatttttgg
    23101 agtaaattgg tttacttctt tgcggaaatc attcgctttt tatcgtttga tattagtatc
    23161 ggagtgggga ttattctctt tacggtcttg attcgtacag tcctcttgcc agtctttcag
    23221 gtgcaaatgg tggcttctag gaaaatgcag gaagctcagc cacgcattaa ggcgcttcga
    23281 gaacaatatc caggtcgaga tatggaaagc agaaccaaac tagagcagga aatgcgtaaa
    23341 gtatttaaag aaatgggtgt cagacagtca gattctcttt ggccgatttt gattcagatg
    23401 ccggttattt tggccttgtt ccaagcccta tcaagagttg actttttaaa gacaggtcat
    23461 ttcttatgga ttaaccttgg tagtgtggat acaacccttg ttcttccgat tttagcagca
    23521 gtattcacct ttttaagtac ttggttgtcc aacaaagctt tgtctgagcg aaatggcgct
    23581 acgactgcga tgatgtatgg gattccagtc ttgattttta tctttgcagt ttatgcgcca
    23641 ggtggagtcg ccctatactg gacagtgtct aatgcttatc aagtcttgca aacctatttc
    23701 ttgaataatc cattcaagat tatcgcagag cgcgaggccg tagtacaggc acaaaaagat
    23761 ttggaaaata gaaaaagaaa agccaagaaa aaggctcaga aaacgaaata aataaggagg
    23821 aatctggtaa tggtagtatt tacaggttca actgttgaag aagcaatcca gaaaggattg
    23881 aaagaattag atattccaag aatgaaggct catatcaaag tcatttctag ggagaaaaaa
    23941 ggctttcttg gtctatttgg taaaaaacca gcccaagtgg atattgaagc gattagtgaa
    24001 acgactgttg tcaaagcaaa tcaacaggta gtaaaaggcg ttccgaaaaa aatcaatgat
    24061 ttgaacgagc ctgtgaagac ggttagtgaa gaaaccgttg accttggtca tgtagttgat
    24121 gctattaaaa aaatagagga agaaggtcaa ggtatttctg atgaagtcaa ggctgaaatc
    24181 ttaaaacatg aaagacatgc cagcactatc ttagaagaaa ctggtcacat tgagatttta
    24241 aatgaacttc aaatcgagga agcgatgagg gaagaagcag gcgctgatga ccttgaaact
    24301 gagcaagacc aagctgaaag tcaagaacta gaagacttgg gcttgaaagt tgaaacgaac
    24361 tttgatattg aacaagtagc tacggaagta atggcttatg ttcaaacgat tattgatgac
    24421 atggatgttg aggctacact ttcaaatgat tataaccgtc gtagcatcaa tttgcaaatt
    24481 gatactaacg aaccaggtcg tattatcggc taccatggta aagtcttgaa ggccttgcaa
    24541 ctgttggctc aaaattatct ttacaactgc tattcaagaa ccttctatat cactattaat
    24601 gtcaatgatt atgttgaaca ccgtgcagaa gtcttgcaga cctatgcgca aaaattggcg
    24661 attcgtgttt tagaagaagg acgtagtcat caaacagatc caatgtcgaa tagtgaacgc
    24721 aagattatcc accgtattat ttcacgtatg gatggcgtga ccagttactc tgaaggtgat
    24781 gagccaaatc gctatgtcgt tgtagataca gaataagtaa aatcagggtt gacctgattt
    24841 tttgctagct agaggaggtt aaactgatgt tgaataagat aagagactat ttagactttg
    24901 ctggtttgca gtaccgtaat cctgataaag cgggagcaga gcgagagaag atgctggcat
    24961 tccgccacaa aggacaagag gcccgaaagg cttttacaga actggccaaa gcctttcaag
    25021 caagccatcc agaatggcaa ctccaacaga ctagtcagtg gatgaatcag gcccagcgtt
    25081 tgagaccaca tttttgggtt tatctacaga gagacggaca agtgacagaa cctatgatgg
    25141 ccttacgttt gtatgggaca tctactgact ttggaatttc tttggaagtc agtttcatcg
    25201 aacgtaagaa ggatgagcaa acactgggca agcaggccaa agttttagac attccaaccg
    25261 ttaaagggat ttattatcta acctactcta atggtcaaag tcaacggtgg gaggcgaatg
    25321 aagaaaagcg tcgtacttta cgcgagaagg tgagaagtca agaagctcga aaagttttag
    25381 tgaaggtaga tgttcctatg acagaaaatt cgtctgaaga agaaatcgta gaaggcttat
    25441 tgaagtctta ttctaaaatt cttccctatt atctagctac gagaaaataa gataatttgt
    25501 aaaacatcat aaatcataca gtccaagagt gaacagtccg ctgtgtaatt cttggtcttt
    25561 ttgtttgcgc tttcgcatta tataataaac ttacaaaaac aattcaaaag gagaacaatt
    25621 atggaagtcg tttcaagtgt tctaaattgg ttttctagca atattttgca gaatcccgca
    25681 tttttcgtag gtttattggt gttgatagga tatgcacttt tgaaaaaacc tgcccatgac
    25741 gttttttcag ggtttgttaa agcaacagta gggtatatgt tgcttaacgt gggtgctggt
    25801 ggtttggtta caacctttcg tccaatctta gcagctctta actacaaatt ccaaattggt
    25861 gcagcggtta tcgaccctta ctttggactt gctgcagcaa acaacaaaat tgcagcagag
    25921 tttccagatt ttgttggaac tgcaactaca gctctattga ttggttttgg aataaatatc
    25981 ttgctcgtag ctcttcgaaa gattacgaag gtaagaaccc tctttattac tggtcacatc
    26041 atggtacaac aagctgcaac agtatctctt atggttctat tcttagtacc acaattgcgc
    26101 aatgcttacg gtacagcagc gattggtatc atctgtggac tttactgggc agttagttca
    26161 aatatgactg ttgaggcaac tcaacgcttg actggtggtg gcggatttgc gattggtcac
    26221 caacagcaat ttgcaatctg gtttgtagat aaagtagcag gacgctttgg taagaaagaa
    26281 gaaagtttag acaatcttaa attacctaag ttcctctcaa tcttccacga tacagttgtt
    26341 gcatctgcta ccttgatgct cgtattcttc ggagccattc ttttaatctt gggtccagac
    26401 attatgtcta ataaagaagt catcacttca ggaactctat tcaatcctgc taaacaagat
    26461 ttctttatgt acattatcca aacagccttt accttctcag tttacttgtt cgttttgatg
    26521 caaggtgtcc gaatgttcgt atctgagttg acaaacgcct tccaaggtat ttcaaacaaa
    26581 ttgttgccag gttcattccc agcggttgac gttgcagctt cttatggatt tggttctcca
    26641 aatgctgtct tgtcaggatt tacctttggt ttgattggtc aattgattac aattgtcttg
    26701 ctcatcgtct ttaaaaatcc gattcttatt attacaggat ttgtaccagt gttctttgac
    26761 aatgcagcca ttgcggtcta cgctgataaa cgcggcggat ggaaagcggc tgttatcctt
    26821 tcctttatat caggtgtcct tcaagttgct ctaggagctc tttgtgtggc ccttctcgat
    26881 ttggcatctt atggtggcta ccatggaaat atcgactttg aattcccatg gcttggattt
    26941 ggatatatct tcaaatacct tggtattgtt ggttatgtac ttgtgtgtct cttcttgctt
    27001 gttattcctc aacttcaatt tgccaaagca aaagataaag agaaatatta caacggtgaa
    27061 gttcaagaag aagcttagta tctagaaaag gagaaataaa atggttaaag tattagcagc
    27121 gtgcggaaat ggaatgggtt catcaatggt tatcaagatg aaggttgaaa atgctctccg
    27181 taagcttaat caaacagatt ttacagtcaa ttcatgcagt gtcggtgaag ctaaaggttt
    27241 agcagtagga tatgacatcg taatcgcttc tcttcatttg attcaagaat tggaagggcg
    27301 aactaatggg aagttaattg ggcttgataa cttgatggat gataaagaaa tcaccgaaaa
    27361 actcagtcaa gcactacagt aaaaggttgg agggggctgg acagaaactg agagttatcg
    27421 tttctgtcct tctccctctt taaataaagg aggcagatat gaatttaaaa caagctttaa
    27481 ttgacaatga ctcgatccga ctaggtttag aggctaacaa ttggaaagaa gcagtcaagg
    27541 tagcagtaga tcccttaatt gaaagtgggg caattttgcc agagtattac gatgctatca
    27601 ttgaatcgac tgaagagtat gggccttact atatcttgat gccaggtatg gctatgcccc
    27661 acgctagacc tgaagctggt gtgcaaagtg atgccttttc attgattacc ttacaaaatc
    27721 ctgttgtatt ttcagatggg aaagaggtat ctgttttgtt ggcactagca gcaacaagct
    27781 caaaaattca cacaagtgta gccattccac aaattattgc cctgtttgaa ttagacgatt
    27841 ctattgcacg tttacaggct tgccagacta aagaagatgt cttagctatg attgaagaat
    27901 ctaaggatag cccttatctc gaaggattgg acttggaaag ttagaaagag gaataaagaa
    27961 atgacaaaaa gaatacctaa tttacaagtt gcattagacc attcagactt gcaaggagcg
    28021 attaaagcag ctgtttctgt tggtcaggaa gtagatatta tcgaagctgg aactgtttgc
    28081 ttgcttcaag ttggaagtga actggctgaa gtcttgcgta gccttttccc agataagatt
    28141 attgtggcag acacaaaatg tgctgatgct ggtggaacag ttgctaaaaa taatgcggtt
    28201 cgtggagcag actggatgac ttgtatctgt tgtgcaacca tccctactat ggaagcagct
    28261 ctaaaggcta tcaagactga acgaggagaa cgaggcgaaa tccagatcga gctttatggc
    28321 gattggactt ttgaacaagc tcagctttgg ctagatgcag gtatctcaca agctatttat
    28381 caccaatctc gtgatgctct tcttgctggt gaaacttggg gtgaaaaaga ccttaataag
    28441 gttaaaaaac tcattgacat gggcttccgt gtatctgtaa caggtggtct agatgtagat
    28501 actctcaaac tctttgaagg tgttgatgtc tttaccttta tcgcaggtcg tggaattaca
    28561 gaggctgcgg atccagcagg agcagcgcgt gccttcaagg atgaaatcaa acgaatttgg
    28621 gggtaaatca tggtacgtcc aattggaatt tatgaaaagg caaccccaac acactttact
    28681 tggctagaac gtttaaattt tgccaaggag ttaggctttg attttgtcga gatgtctatt
    28741 gacgaacgtg acgagcgttt agcaagactt gactggagta aggaagaacg cttggaagtt
    28801 gtcaaagcaa tctatgaaac tggtgttcgt attccttcta tctgtttttc aggccatcgt
    28861 cgctacccat tgggttcaaa agatccagtt ctagaggaaa aatctctaga actcatgaaa
    28921 aaatgtatcg aattagctca agacttggga gttcgtacga ttcaattagc tggttacgat
    28981 gtttactatg aggaaaagtc accccagaca cgccaacgtt ttatcaaaaa tttgagaaaa
    29041 gcctgtgact gggctgaaga agctcaggtg gtacttgcta ttgaaattat ggatgatcct
    29101 ttcatcaata gcatcgaaaa atatttggct atagaaaaag agattgactc tcccttcctc
    29161 tttgtatatc cagatattgg taatgtgtct gcatggcata atgatatcta tagtgagttt
    29221 tatcttggtc atcatgccat cgcagctctc catctcaagg atacttatgc agtgacagaa
    29281 agttcaaggg gccagttccg agatgtacct tttgggcaag gttgtgtcaa atgggaagaa
    29341 gctttcgata ttttaaagga aaccaattat aatggacctt tcctaatcga aatgtggtct
    29401 gaaaattgtg aaacagtaga agaaacacgc gcagccattc aagaggcgca agcttttctc
    29461 tatccactca ttaagaaagc aggtttgatg taagatgaat caagtaatca atgctatgcg
    29521 taaacgagtc tgtgctgcca atcaatcatt gccaaaacat ggacttgtca aatttacctg
    29581 ggggaatgta tctgaagtca atcgcgaact cggtgtcatt gttatcaaac catcaggcgt
    29641 ggattatgac gaattgacac ctgaaaacat ggtagtgact gatctagatg gtaagatcct
    29701 agaaggggat ttaagaccat cttccgacct cccaactcat gtgcaattat ataaggcttg
    29761 gtcagaaatt ggtagtgtgg ttcacaccca ttcgacagaa gctgttgctt gggctcaggc
    29821 aggtcgtgat attcctttct acggaacaac ccatgcagat tatttctacg gttcaatccc
    29881 ttgcgcccgt agtttgacca aggacgaagt agaagtggcc tatgaaaaag atactggcct
    29941 ggttatcgta gaagagtttg aacatcgcgg acttaacccg gttgaagtac caggaattgt
    30001 tgtacgcaat cacggtccat tcacctgggg caaaaatcca gagaatgctg tttatcactc
    30061 tgtcgtacta gaggaagtat caaagatgaa tcgctttaca gaacaaatca atccaagagt
    30121 tgaacctgct ccccagtaca tactagaaaa acactaccaa cgtaaacatg gaccaaatgc
    30181 ttattatggt caaaagtaag aacgatgaag gaggagaaaa agataaattt agctcctctt
    30241 tttacatttg atttttattg agagtaaagt tggagttgaa gtaattttga aagatttttt
    30301 agaaatagcg cttgatatat atggtaaaat aaaaagaatt gctgtgatat caatagattt
    30361 gggggatttt ttaatatggt actggataag gcaagttgtg atttgcttca atatttgatg
    30421 gatcaagaaa cgtccaaaac gattatggcg atttcgaaag atttgaaaga gtcaagaagg
    30481 aaaatttatt atcacattga caaaatcaat gctgctctgg ttgacgaggc gcttcacatc
    30541 attagtattc cacgaattgg tattcactta acggaagagc agagagatgc ttgttgtaaa
    30601 ctattatcgg aagtagattc gtacgattat atcatgagtg cgcatgaacg tatgatgata
    30661 atgttactat ggataggtat ttctaaagaa cgtattacga ttgaaaaatt gatagagtta
    30721 acagaggtat ctaggaatac tgttctcaat gatttgaata gtattcgtta tcaactaact
    30781 ttggaacaat atcaggtgac cttgcaagtg agcaagtcac agggatacca ccttcatgcc
    30841 caccctctta ataaaattca gtatcttcaa tcgcttctat atcatatttt tatggaagaa
    30901 aatgccactt ttgtatctat tttagaagat aagatgaaag agaggttaga tgatgagtgt
    30961 ttgctttctg ttgaaatgaa ccaatttttt aaggaacagg ttcctttagt tgaacaagat
    31021 ttagggaaga aaataaacca tcatgaaata acttttatgt tgcaggttct accttatttg
    31081 ctgttaagct gtcataatgt tgaacagtat caagaaagac atcaggatat agagaaagaa
    31141 ttttctttga taagaaaaag aatagagtat caggtgtcta agaaattagg agaacggttg
    31201 tttcaaaatt ttgaaatttc tttgtcagga cttgaagttt ctcttgtagc tgttctcctc
    31261 ctctcctatc gtaaagattt ggatattcat gcagaaagtg atgattttcg gcaattaaaa
    31321 cttgctttag aagaatttat ctggtatttt gaatcacaaa tccgaatgga gattgagaac
    31381 aaggatgatt tgttacgaaa tttgatgatc cactgtaaag ccttgttatt tagaaagact
    31441 tacggtattt tttctaaaaa tcctctaaca aaacaaattc gatccaagta tggagaatta
    31501 tttttagtca ctagaaaatc tgcggaaatt ttagaaggag catggtttat tcggctaaca
    31561 gacgatgata ttgcctattt gacgattcat attggaggat ttttaaagta tacaccatcg
    31621 tctcaaaaaa atatgaaaaa agtttatctc gtttgtgatg aaggtgttgc ggtttcgaga
    31681 cttttgctga aacaatgcaa actttatttt ccaaatgagc aaattgacac tgtatttaca
    31741 acagaacaat ttaagagtgt ggaagatatt gcacaagttg atgtagtgat tactactaat
    31801 gatgatttgg atagcagatt tccgatttta agggttaatc ctatccttga agcagaagat
    31861 attttgaaaa tgctagacta tcttaaacac aatatatttc gtaataagag caaaagtttc
    31921 agtgaaaatc tttctagtct tatttcgtct tatattgtag acagcaagtt ggctagtaag
    31981 ttccaagaag aggttcaaac acttataaat caagaaatag tagttcaagc ttttttggaa
    32041 gatatttgaa ggacagtcca atgatgaaca caaacctgtg tttttcttgg tcttttttag
    32101 tgttttgaag ggtggtatac taatctcaaa gataacaatt atatccaaag gaggcaacat
    32161 atgccaaacg tcaaagaaat tacaagagag tcatggattt tagccacttt cccagagtgg
    32221 ggaacatggt tgaacgaaga aatcgaagaa gaagtcgtac ctgaaggcaa ctttgccatg
    32281 tggtggctag gcaactgtgg tacttggatt aagacaccag ctggtgctaa cgttgtcatg
    32341 gacctttggt caaaccgtgg aaaatcaacc aaaaaagtga aagatatggt tcgtgggcac
    32401 caaatggcaa atatggcagg tgttcgtaag ttgcaaccaa acttgcgtgt tcagccaatg
    32461 gttatcgatc catttgctat caacgaacta gactattact tagtttcaca cttccacagt
    32521 gatcatatcg acccatacac agctgcagca attctcaaca atcctaagtt agagcatgtt
    32581 aagtttatcg gtccttacca ctgtggacga atctgggaag gatggggtgt tccaaaagaa
    32641 cgtatcatcg ttgttaaacc aggtgacact atcgaattaa aagatatgaa gattcatgca
    32701 gtagaatcat ttgaccgtac ttgcttggta actctcccag tgaacggtgc tgatgagaca
    32761 ggcggtgaac ttgctggctt ggctgttaca gatgaagaaa tggctcaaaa ggctgttaac
    32821 tatatctttg aaacaccagg tggaaccatc tatcatggtg cagattctca cttctcaaac
    32881 tattttgcaa aacatggtaa agactttaaa attgatgttg ctttgaataa ctatggtgaa
    32941 aatccggtag gtatccaaga caaaatgaca tctatcgacc ttcttcgtat ggcagaaaat
    33001 ctgcgtacca aagtcattat cccagttcac tatgatatct ggtctaactt catggcttct
    33061 actaatgaga ttctagaact ttggaaaatg cgaaaagatc gcttgcaata cgatttccat
    33121 ccatttatct gggaagttgg cggtaagtac acttatcctc aagatcaaca cttagtagaa
    33181 taccatcatc cacgtggttt tgatgattgt tttgaacaag actctaacat tcaatttaaa
    33241 gctttgctat aatataaaaa tattctttgg aggttatccg tatgttgcat gatacggata
    33301 attttcatat aatagtaaaa tagaatgtgt gattcaataa tcacctcaaa tagaaaggaa
    33361 attctatgtc aaatctatct gttaatgcaa ttcgttttct aggtattgac gccattaata
    33421 aagccaactc aggtcatcca ggtgtggtta tgggagcggc tccgatggct tacagcctct
    33481 ttacaaaaca acttcatatc aatccagctc aaccaaactg gattaaccgc gaccgcttta
    33541 ttctttcagc aggtcatggt tcaatgctcc tttatgctct tcttcatctt tctggttttg
    33601 aagatgtcag catggatgag attaagagct tccgtcaatg gggttcaaaa acaccaggtc
    33661 acccagaatt tggtcatacg gcagggattg atgctacgac aggtcctcta gggcaaggga
    33721 tttcaactgc tactggtttt gcccaagcag aacgtttctt ggcagccgaa tataaccgtg
    33781 aaggctacaa tatctttgac cactatactt acgttatctg tggagacgga gacttgatgg
    33841 aaggtgtctc aagcgaggca gcttcatacg caggcttgca aaaacttgat aagttggttg
    33901 ttctttatga ttcaaatgat atcaacttgg atggtgagac aaaggattcc tttacagaaa
    33961 gtgttcgtga ccgttacaat gcctacggtt ggcatactgc cttggttgaa aatggaacag
    34021 acttggaagc catccatgct gctatcgaaa cagcaaaagc ttcaggaaag ccatctttaa
    34081 ttgaagtgaa gacggttatt ggatatggtt ctccaaacaa acaaggaact aatgctgtac
    34141 acggcgcccc tcttggagca gatgaaactg catcaactcg ccaagccctc ggttgggact
    34201 acgaaccatt tgaaattcca gaacaagtat atgctgattt caaagaacat gttgcagacc
    34261 gtggcgcatc agcttatcaa gcttggacta aattagttgc agattataaa gaagctcatc
    34321 cagaactggc tgcagaagta gaagccatca tcgacggacg tgatccagtc gaagtgactc
    34381 cagcagactt cccagcttta gaaaatggtt tttctcaagc aactcgtaat tcaagtcaag
    34441 atgccttgaa tgttgtggca gctaaattac caaccttcct aggtggatca gctgaccttg
    34501 ctcactcaaa catgacttat atcaagacgg atggacttca agacgatacc aatcgcttga
    34561 atcgtaacat tcagtttggt gttcgtgaat ttgcaatggg aacaatcttg aacgggatgg
    34621 cccttcatgg tggacttcgt gtatacggtg gaactttctt cgtcttctct gactatgtga
    34681 aggcagctgt ccgcttgtca gccttacaag gacttcctgt gacttatgtc tttacccatg
    34741 attcaatcgc agttggggaa gatggtccga ctcacgaacc agttgagcat ttagcaggtc
    34801 ttcgtgctat gccaaatcta aatgttttcc gtccagcaga tgcgcgtgaa acgcaagcag
    34861 cttggtacct tgcagtgaca agtgagaaaa caccaactgc ccttgtcttg acacgtcaaa
    34921 acttgactgt tgaagatgga acagacttcg acaaggttgc taaaggtgct tatgttgtat
    34981 atgaaaatgc agccgacttt gataccatct tgattgcgac aggttcagag gttaatcttg
    35041 ctgtctcagc tgctaaagaa ttggctagtc aaggcgaaaa aatccgcgta atcagcatgc
    35101 catctacaga tgtctttgat aaacaaaatg cagcttacaa ggaagagatt cttccaaatg
    35161 cagtccgtcg tcgtgttgca gtcgaaatgg gtgcaagtca aaactggtac aaatatgttg
    35221 gtctcgatgg tgccgttcta ggtattgata ccttcggagc ctctgcccca gcaccaaaag
    35281 tattggcaga atatggcttt actgtagaaa atcttgtaaa aattgttcga aacttgaaat
    35341 aatcctaaaa atcagggcgt aagctctggt ttttcttgcc agaaaagtaa ggtacaatct
    35401 tgtaaaagta gctgaaattt gatatagtag tcctatgtaa aagacaaagg agaaaacaat
    35461 gaatccaaat attacttttt taatcatgct tgtaggtatg atggccttga tgttctttat
    35521 gcaacgttct caaaagaaac aagctcaaaa gcgtatggaa agcttaaata aactacaaaa
    35581 aggctatgaa gtgattacaa tcggtggact ttatggaaca gtcgatgaag tagatacgga
    35641 gaagggaaca atagttcttg acgtagatgg agtttacttg acttttgaac tagctgctat
    35701 caagacagta ttaccgctga aagaaacagc ttcactagaa ggcgcaattg aaaaataaga
    35761 cgggatcacg aactcccgtt tttctataaa agaaaggaaa tgggatgaaa aaattagtct
    35821 ttgtctgtct gggaaatatt tgccgtagcc ctatggccga gtttgttatg aaatcaatga
    35881 cagataacta cgaaatccaa agtcgagcaa cttcctcttg ggaacatggc aatccgattc
    35941 ataaggggac tcagggaatt tttcaagagt atgagattcc ttatgacaag aacaagacat
    36001 cgcttcagat tagtaaggaa gattttgaag cctttgatta tattatcgga atggacgctt
    36061 caaatatttc tgacttacgt cagatgtgtc cagtagactg tcaagataag atttactcat
    36121 tttcatctga aagtgttcca gacccttggt atacaggaga ttttgaagaa acctatcgac
    36181 gtgttcaaga gggctgtcaa gcttggttag aacgtttaga aaaggagagt taaggtggaa
    36241 aatcttacga atttttacga aaagtatcgt gtctatctga ctcgtccacg tttagagctt
    36301 ttggcagtag ttaccattgt tttctgtgct gtactcgtct tttttctaaa tattccagga
    36361 aaaggtgtct taaaactcga taatggaacg attgtttatg atggcagtct tgtccgtggt
    36421 aaaatgaatg gccaaggtac cattaccttc caaaatggag accaatatac aggtggcttc
    36481 aacaatggag ccttcaacgg aaaaggtacc tttcaatcta aagaaggctg gacctacgaa
    36541 ggtgattttg taaatggtca ggctgaagga aaagggaaac taacaacaga acaagaagtc
    36601 gtttatgaag gaacttttaa acaaggcgtt tttcaacaaa aataaagcct ccttatcaaa
    36661 ggaggtatta ttagaatcac aaggtaagcg cttacctgta aatccctttc tttccaaatc
    36721 cctcttccaa gcaagtttgt gaaataaaaa atatttgaaa taaatttcac aaacttcaaa
    36781 gataaaactt gataagaaaa gaaaatgaga aaagtttcac aagagtttaa aaattctttg
    36841 tgaaatgttt atgaaactgt ttacaaagtt gaaataatgc gttataataa acttgtgaaa
    36901 aaattaacaa aggatatcgt tccttgaaag ctatggagga aaatatggct gataaaaaaa
    36961 ctgtgacacc agaggaaaag aaactcgttg ctgaaaaaca cgtagatgag ttggttcaaa
    37021 aagctctagt tgcccttgaa gaaatgcgta aattggatca agaacaagtt gactacatcg
    37081 ttgccaaagc atcagtagca gctttggatg cccacggaga attggcttta catgcctttg
    37141 aagaaacagg acgtggtgta tttgaagaca aagcaactaa gaacttgttt gcctgtgaac
    37201 acgtagtaaa caacatgcgc cacactaaga cagttggtgt tatcgaagaa gacgatgtaa
    37261 caggattgac tcttattgct gaaccagttg gtgttgtttg tggtattact ccaacaacaa
    37321 acccaacatc aacagcaatc ttcaaatcat tgatttcatt gaagacacgt aacccaatcg
    37381 tctttgcctt ccatccatca gcacaagaat catctgctca tgcagctcgt atcgtccgcg
    37441 atgcagctat cgcagctggt gctcctgaaa actgtgtgca atggattact caaccatcta
    37501 tggaagcaac aagtgccctt atgaaccacg aaggtgttgc gacaatcctt gcaacaggtg
    37561 gtaatgccat ggttaaggcg gcttattcat gtggtaaacc agctcttggg gtaggtgccg
    37621 gaaacgttcc agcttatgtt gaaaaatcag caaacattcg tcaagcagca cacgatatcg
    37681 tcatgtctaa atcatttgat aacggtatgg tctgtgcatc tgaacaagca gttatcattg
    37741 ataaagaaat ttacgatgaa tttgtagcag agttcaaatc ttaccacact tactttgtaa
    37801 acaaaaaaga aaaagctctt cttgaagagt tctgcttcgg tgtcaaagca aacagcaaaa
    37861 actgtgctgg tgcaaaattg aacgctgaca tcgttggtaa accagcaact tggattgcag
    37921 aacaagcagg atttacagtt ccagaaggaa caaacattct tgctgcagaa tgtaaagaag
    37981 ttggcgaaaa tgagccattg actcgtgaaa aattgtcacc agttattgca gttttgaaat
    38041 ctgaaagccg tgaagatggt attactaaga ctcgtcaaat ggttgaattt aacggtcttg
    38101 gacactcagc agctatccac acagctgacg aagaattgac taaagaattt ggtaaagctg
    38161 ttaaagctat tcgtgttatc tgtaactcac cttctacttt tggtggtatc ggggacgttt
    38221 acaatgcctt cttgccatca ttgacacttg gatgtggttc ttacggacgc aactcagttg
    38281 gggataacgt tagtgccatt aacctcttga atatcaaaaa agtcggaaga cggagaaata
    38341 acatgcaatg gatgaaactt ccttcaaaaa catactttga acgtgattca attcaatacc
    38401 ttcaaaaatg tcgtgacgtt gaacgtgtca tgatcgttac tgaccatgcc atggtagagc
    38461 ttggtttcct tgatcgtatc atcgaacaac tggaccttcg tcgcaataag gttgtttacc
    38521 aaatctttgc ggatgtagaa ccggatccag atatcacaac tgtaaaccgt ggtactgaga
    38581 ttatgcgtgc cttcaaacca gataccatca tcgcactcgg tggtgggtct ccaatggatg
    38641 ctgccaaagt aatgtggctt ttctacgagc aaccagaagt ggacttccgt gaccttgtcc
    38701 aaaaattcat ggatatccgt aaacgtgcct tcaagttccc attgcttggt aagaagacta
    38761 aattcatcgc gattccaact acatctggta caggatctga agtaacacca tttgccgtta
    38821 tctctgataa agcaaacaac cgtaaatacc caattgctga ctactcattg acaccaactg
    38881 tggcaatcgt agaccctgct ttggtattga cagttccagg atttgttgct gctgatactg
    38941 gtatggacgt attgactcac gcaacagaag catatgtatc acaaatggct agtgactaca
    39001 ctgatggttt agcacttcaa gccattaaat tggtctttga aaatctcgaa agctcagtta
    39061 agaatgcaga cttccactca cgtgagaaaa tgcataacgc ttcaacaatc gctggtatgg
    39121 cctttgccaa tgccttctta ggtatttctc actcaatggc ccataagatt ggtgcgcaat
    39181 tccacacaat ccacggtcgt acaaatgcta tcttgcttcc gtacgttatc cgttacaatg
    39241 gtacacgtcc agctaagaca gcaacatggc ctaagtacaa ctattaccgt gcagatgaaa
    39301 aataccaaga tatcgcacgc atacttggac ttccagcttc tactccagaa gaaggggttg
    39361 aatcttacgc aaaagctgtc tacgaactcg gtgaacgtat tgggatccaa atgaatttta
    39421 gagaccaagg aattgacgaa aaagaatgga aagaacattc tcgtgaatta gccttcctgg
    39481 cttatgaaga ccaatgttca ccagctaacc cacgtcttcc aatggtagac catatgcaag
    39541 aaatcatcga agatgcatac tatggctaca aagaaagacc aggacgccgt aaataattgt
    39601 ttatcagtct agaagcaaga caaaaactca atttgaggga aagatccagt aatttttcta
    39661 tgataaaagg catcctatca aggtttttga acacctgata ggatgccttt ttatgatatt
    39721 gaggcctttt tgcccttttt gaaaaactag aatagaaaca aaatatataa tagattgaaa
    39781 ctagaatagt acacatctgc ttctaaaaca ttgttagaat tcgatttgac tgtcctgatc
    39841 gatttgtcct attcctattt cattttatta tataaaaaat atagtatagt agactgaatc
    39901 taaaatagta cgaaacaatt gctaaaacat ttatagaaat taattttact ttcctgatag
    39961 agttgttcac atcttatttc aattcactat agtttaattt aagagtagta tttactaagg
    40021 cccaattaaa atcaaagagc aaactagaaa acgagtgcca ttcagctcaa aacactgatt
    40081 tgagattgca gataagacta gccccctcat taacagattt acgataaaac gatgacaagg
    40141 tgtgttgctt tttgatttct aaagagtata atgatagatc tctataaaat aagtgcgaag
    40201 gaaatgagct tttatagtcc tttcgtttta aaatactatc tcagatattc ttatatcgac
    40261 aagaagtttt tgagtcattc cctcatcata catattaaat aaatagtggc tcattcaatt
    40321 tttcactaga ataataagct agtatagtaa actgaaataa gatataaaca aataaattgg
    40381 agcttaacat ccatttccag caatttttta gaaactacag tggactattc tagattcaac
    40441 atattataaa aactagagta aaagaaaagg attggatctt gtgtaatgca ggatccaatc
    40501 ctttcaatca ttttgtccaa cttttggagg ttcctacaat gtagtcgtca ttaataaaga
    40561 cagatgggaa tgacagtgtt cctatttatt ttgatagaga tcgatgaatt ctttagatag
    40621 caactgaata atctctgttg aagccatttg gtcttctgca tgcataaata gcaaggagaa
    40681 tcctattttt tctccagtag cttctttttg tatgagatta gagtgaatct tgtgcgcttc
    40741 tactaaggag tcttccgctt cttcaacttt aattttcgct tcttttaaat ttcctgcctt
    40801 agctagttgg atggcttcaa taaaggatga tttggctgct ccactattgg caatgagctg
    40861 aaaacagata tattccattt cttctgtcat cttatttctc ctatccatgc aagtgcttgt
    40921 tccagaactt ttgctccatt catcattccg taatcccgca tatcaatggt atctacaggg
    40981 atatttcctg caatttcttt cacagcaagt aactcataac gaatttgtgg cccaattaga
    41041 atgacatctg cttcatggat attcttttta gcttctgtca ttgattttgc ttggatagag
    41101 atttcaatcc cacgttcagt cgcactttgt tgcatttttt taacaagcat acttgtcgac
    41161 attcccgcat tacatactaa taaaatttgt ttcataatct taaccttcca tttcttgttc
    41221 aacaactttg tcattaactt tgataaatgg aatgtataga agaactccaa gtgcaaagat
    41281 gatgaattga actagaactg ctctcacgtc ccctgctgtt gctaaccatg catttaagaa
    41341 tactggtgta gtccaaggaa cttgtataaa tgcaggactc atgaatcctg taactgttgc
    41401 taagtagctg attaaaatac caaggactgg aactgtgata aatggaatag ctaatgaaat
    41461 gttataaacg attgggtaac cgaataatac tggttcattg atattgaaga taccaggtcc
    41521 aaaagataat ttagccacgt ttttagagac agcattgcga ctcactaaga atgttgctat
    41581 taataaacat aatgtagatc cactaccacc cattaaagcg aatgtttgta tttgtgatag
    41641 gttgatgatg tgtggaatgg cttgtccatt atttgctgca gtgatgtttt cagtaatgtt
    41701 aattaatagt aatggttcta ggatggcact gtaaataact gcttggtgaa taccaaatag
    41761 ccataacata tttcctaaag agtaaataat aatgaccccg attaagcttg taccaatatg
    41821 acgaattggt tcttgaataa agattgtaat gattgagatt aagttcattc cagttatatt
    41881 gaataataat gctgaaacaa ccccaaataa ggagatgacg gtcatgactg gaagtaatac
    41941 gctaaatgat ctactaacag ctggtggaat attttcacca aggttcattt gtaaagcttt
    42001 aacgtttgat aattcaatga ataattctgt tgcaataatc gctacgataa ccccggcgaa
    42061 cattgcgcct gtacctgtgt tgttgaatga aagaacacct gaaatgttta ccgcatcttt
    42121 tgctccgtca ggaactacag aaactgtatt tggcatcatc acaattaaag aaactaatga
    42181 tagcattgat gctgctaacg ggttttcgaa atctctgttt ttagctaaga aataaccaac
    42241 cattacagca ataatcatac ctgaaatact taaagtaccg tttgcaattg ttattcccca
    42301 atattggaat cttgttaatg tatccccttg gaaaatccac ttaaataccg tgttgttcaa
    42361 aagaacgatt aaacctgcca aaatatataa tggcattact gttacgaatg catctcttag
    42421 ggtttttaaa tgaatttggt tccctagttt accagcaaag gtggcaaatt gatctataaa
    42481 ttttgagttt ttcatctgaa tatctcctct ctttactcct caatttctac ttcaaaaccg
    42541 ttattgtcac ttactttgcg ataccatctt cctgagctct tgatggttct cttttgcgtt
    42601 tctaaatcaa cggagataaa tccgtaacga ttcttatatg cattattcca agaccagcaa
    42661 tcaaatgcgg tccaagcgtg gtatccaaaa cagtgacttc cctcttcaat ggctttatgt
    42721 agccatctta aatgttcttc ataaaattca atacgataca cgtcatcgat aactccattt
    42781 tcatcgataa accgtgcttc gttttcaaca cccattccgt tttcactgat aaaccatgga
    42841 atattatcat attcttcctt cacaatcata gcaatatcat aaatggcttt cggaaaaatt
    42901 tcccaaccac gatatggatt catgcgacgc tccggccatt catactcttt gaagtattgg
    42961 tctggcatcc agggcgtctg atattcctca ggatttgctt gtgcttgaac acgttttgga
    43021 tggtagtagt ttactccaag aaaatcaacc gtatttgatt tcatcagttg aagctctttt
    43081 tcggtatgac tccataacac gccatctctc tctagctgtt ttaccaatct ttctgggaaa
    43141 gttcctttaa cagctggatt caagaagact ttgttaaaga agtcttctgt aaatcgactt
    43201 gcttctaagt cttctggaga attacttctt ggataagcag gtgtcaagtt taaaataatc
    43261 ccaatctttc catcaagttc taatgagcga tatagttgaa tcacttttgc actagcaagg
    43321 tttagattat agatgacttg tacggcctct tttccctttc cttttagatt tggataatgg
    43381 aaagcatata agtatcctgc ttctggaatg accattggct cattgaaagt tgtccagtaa
    43441 tgaaccttat ctccaaagca tgtgaaagca gtcttggcaa acttcacgaa taactccact
    43501 acatgtttgc tttcccaacc accgtatttt tgaagaagtt ccactggtaa atcaaaatga
    43561 tgtaaattca tcacaagatc catctggttc tttttagctt cttcaatgat ggcattgtag
    43621 aaagcaatac cttttggatc aggctcacct gtctctaaat tcttgatgag tcgactccat
    43681 tggatggaag tgcggaaaga attaactcca atttccttca tcaagtggaa atcttcggtg
    43741 taagtatgaa aaaagttact ggctacaaga ggtccgacat tatcgaaaaa atcttctgga
    43801 tgcgttttga accagtagtc catcacattt tcatgtactt ttccatattg accttctgtc
    43861 tgaggtccgc tagaagcagc tccccaccaa aacagattag gaaatactaa cttttttttc
    43921 atgctcaacc tcctttctat tattctatac ataaagtata gcataatttt aaaatttgtc
    43981 tagacatttt taaaaattgt tgatacatat cttgtgtttg cctcatttct tgaactttgt
    44041 tatactacta ttagaatatt atagagagaa ccagattaaa tgagtacaaa atatttattt
    44101 atttacaatg agattcgtga aaagattctt tgtaataaat ataccatgaa cgaacaattg
    44161 cctgatgaaa tgacattagc taaacagttt gcctgtagtc gaatgacgat caaaaaagct
    44221 ttagacttgt tagtttctga gggcttaatt tttagaaaac gtgggcaggg aacctttgtt
    44281 ctctctcgtg gcagctcaaa aagaaaatta atcgttccag aaagagatat ccggggactg
    44341 acaaaaatat ctgaagatgc tcattctaca attgactcga ggattattca cttcaaatta
    44401 gaatttgcaa atgaattttt agcagaaaaa ctacaggtcg ctttgcagag tccagtttat
    44461 aatatttacc gtctgcgtat tattgacggt aaaccttatg ttctggaaca aacttatatg
    44521 agtaccgatg ttattccagg tattactgaa gatattttac aaaaatcgat ttacaattac
    44581 attgaaggaa agttaggatt gcatattgcc agtgctacaa aaatcttgcg agcttcttct
    44641 agttcagaaa atgagcaaca ttacttgcag ctccttccaa cggaaccggt atttgaagta
    44701 gaacaagtgg cttatttgga taacggaact ccgtttgagt actcgattag tcgtcatcgc
    44761 tatgatttat ttgaatttaa ttcttttgca ttacgacatt cctcctagga gaaaatgtga
    44821 aaatgaagcc aatcttttac agactctagt ttaagaaaaa tttaaaacag ggcaagaagg
    44881 tcccatctat gcttaaatgg tttctctttt ctaaataaga tggctttaaa agagtgatcg
    44941 ttttatccat catgttgaaa aatatcttcg tatagcttat agagtaggta ctgaaattgt
    45001 tcacctgatc tacttcttat agttatttag ttttaaatag tgtttcaaac attcttacac
    45061 tgacgagaag tttttgagtc ttttcttgta acacatatag tatactgtgg ttagaatagt
    45121 agactgtgac ttctaacaaa ttgctagaaa tgaatttcaa tctcccaatt tatttgctta
    45181 tatattattt taatatatta aacaaattct gaatcataat catttaaaaa aattttattt
    45241 ttttattttt cattacgaat aatatagatg aaggggaaag agtatgaaaa cagaactgtt
    45301 tcttttgcta ttagttcaaa aggagaaaaa atgaaagtag aaaatatttc gtatagggtg
    45361 gatcatcgta tattgtttga taatatttct tttgatactt cgagttcagg cgtgacatta
    45421 attactggta aaaatggtac aggaaagtca actttactat agtagattga aactagaata
    45481 gtacacctct acttctaaaa tattgttaga aatcgatttg actgtcctgt tcttatttca
    45541 ttttactaca tcttaaattg agtatgaaga aagtgcgctc ccatgtcctg ggaacgcact
    45601 ttcttcatat ttttcatatt cttgaatcca tcgataaaga ctattgggat gaatttttaa
    45661 agttgaacta atcattttta caggatgagg tttacagcag agagtttgaa ggctttatca
    45721 aaggtttttc ttggcataat gacttttcct cgtttccact taattttgtg tctactttat
    45781 tataccaagt ccacccttaa gttagataat aaatctaact taaggaagct aaaaggatga
    45841 gaatccaggt ggtcaagagt cccaaactta agctgatggg gacacccaga ataatttgct
    45901 ttttgaaggc aaggccgcgt tcctctatat tgggaagtga gagttgaatg agagaaccag
    45961 ctgatgaaaa gggtgagata ttagtagata gagcgccaat aacggtggct gttgtgagta
    46021 agtgaatatc aatctgagga ttttgagcac tgatgatagc aatgatggga aagagggctg
    46081 gagctacaac ggatagggtg gaactaaaga gtgacatcac tccggctatc acacaaaaga
    46141 acagaggtaa ccagaaatga ggaatggttg ttgtcatgag gtgccctatc agtgtgacta
    46201 aacctgactt gaccgctaga gacattagta agctcatgcc gcagagcatg ataattgtag
    46261 cccagggaac cttagctaaa atggcttctt gcttccctaa tttgagcctt aaggcgaggc
    46321 agaccatgag tattgagaca aagccaatat caaatgtttt ttgataagta gctatccagg
    46381 cgatgtttgg gaaaatgaga tgcaacaagg gaaaaagcca aaccaaaacc atgctgctga
    46441 tcatgagcaa ggtggtttgt ctttgaacct tgctgaggag tggtggttgg tcaatagtca
    46501 aggatgagtt tgttcttccc ttactatagt gactgtaaca ggataataaa agcaagacga
    46561 tgagtgggta gataatgctg acgataaaga tatgattgcc aagtgaaaaa gcttgctctt
    46621 cccatcccat ttgcttaaac aggccttgaa agacaatgcc tgagctactg gttatcaaat
    46681 tagcccctcc tgaagctccc caattgacgg cttgagctcc aatcaaaggg tgtttgtccg
    46741 ctttttgaca gagggtaatc gctagaggac agcaaacggc catagtagtg aaaaatccag
    46801 cacctaaagc agacaaaagg gttgccatca ggtataaaat catgtagagg gcgttagggt
    46861 gggtgcgtgt gcggtagaga atgtgttgag ccaaaacatc aagagtaccg ttagttgttg
    46921 caacgttata aaagagagag acgctaaaaa tggtaaaaaa gagtgaggtt ggccaaaaat
    46981 gaagaagttc tttggggctt aatcccatga gagtggttgc gatgaggtaa gaaaaagcaa
    47041 tagccagcag gccaatattg attttggtgc ggtaaccaat tccaatggct agagcaatgg
    47101 cgctaatcat tattaaatga atcattgaat tgtcctttca gttagaatat ggaaataggt
    47161 tggcaatttt ggcgctcaaa agaccacctg tttcctattg gtacttgact attatacaca
    47221 aaaaaaatac aattgtcttg acaattgtat tgacacttgt tagaattaaa aatgaggtat
    47281 tcaggcttgt gatttcctat ggaagttaat agtgattgcc tctaatgctt acaagtgata
    47341 ttaaaaatag aggacctagt gatgtcaatc atttcaactg atttaacccc ttttcaaata
    47401 gatgatacat tgaaagcagc cttgcgagaa gatgttcatt ccgaagatta cagtaccaat
    47461 gccatttttg atcatcatgg ccaagccaag gtgtcgcttt ttgccaagga agctggtgtt
    47521 ttagcggggc taaccgtttt tcaaagggtt tttaccctat ttgatgccga ggtgaccttc
    47581 cagaatcctc atcaatttaa ggatggggat cgtttgacta gtggcgattt ggttttagaa
    47641 atcataggct cggtgagaag tctcttaaca tgtgaacgcg ttgccttgaa ttttttacaa
    47701 catttatcag ggattgcttc gatgacagct gcttatgtag aagccttagg cgatgattgc
    47761 attaaggtat ttgatactcg aaaaactact cctaatttac gtctttttga gaaatatgcc
    47821 gtgagagttg gcggtggcta taatcatcgc tttaatttat cagatgctat cctgctaaaa
    47881 gacaatcaca ttgcggcagt aggtagtgtt caaaaggcaa ttgctcaagc gcgtgcctat
    47941 gccccttttg tgaaaatggt cgaggtggaa gtggaaagcc ttgctgctgc cgaagaagct
    48001 gcggcggcgg gtgctgatat tatcatgttg gataatatgt cattggaaca gattgaacag
    48061 gccattaccc taattgcagg acgttctcgg attgaatgtt ctggaaatat tgatatgacc
    48121 actattagcc gttttcgtgg tttagcgatt gattacgtct ccagtggtag tttaacccat
    48181 agtgctaaga gtcttgattt ttccatgaag gggttaacct accttgatgt ctaagttgta
    48241 aaataaacta actttttaaa ggatgtcttt cctctagaac gagttttatg tcagatagtt
    48301 taaacgcctc ttcaaatata gtaaaatgaa ccaaaaatag tacacaatgt g
//
LOCUS       DBERXF010000012        45022 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.12, whole genome shotgun sequence.
ACCESSION   DBERXF010000012 DBERXF010000000
VERSION     DBERXF010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 45022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45022
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.12"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..245)
                     /locus_tag="ACL8JK_000777"
     CDS             complement(<1..245)
                     /locus_tag="ACL8JK_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGS1785695.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESN"
     gene            222..494
                     /locus_tag="ACL8JK_000778"
     CDS             222..494
                     /locus_tag="ACL8JK_000778"
                     /inference="COORDINATES: protein motif:HMM:NF036719.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGS1785696.1"
                     /translation="MFTCFIIHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSG
                     KIKYHEDSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            688..2022
                     /gene="trmFO"
                     /locus_tag="ACL8JK_000779"
     CDS             688..2022
                     /gene="trmFO"
                     /locus_tag="ACL8JK_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HGS1785697.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            2106..2843
                     /gene="pyrH"
                     /locus_tag="ACL8JK_000780"
     CDS             2106..2843
                     /gene="pyrH"
                     /locus_tag="ACL8JK_000780"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGS1785698.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2852..3409
                     /gene="frr"
                     /locus_tag="ACL8JK_000781"
     CDS             2852..3409
                     /gene="frr"
                     /locus_tag="ACL8JK_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGS1785699.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3469..4323
                     /gene="cvfB"
                     /locus_tag="ACL8JK_000782"
     CDS             3469..4323
                     /gene="cvfB"
                     /locus_tag="ACL8JK_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HGS1785700.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKFRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4332..4547
                     /locus_tag="ACL8JK_000783"
     CDS             4332..4547
                     /locus_tag="ACL8JK_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGS1785701.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4633..5601
                     /locus_tag="ACL8JK_000784"
     CDS             4633..5601
                     /locus_tag="ACL8JK_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGS1785702.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            5794..6294
                     /locus_tag="ACL8JK_000785"
     CDS             5794..6294
                     /locus_tag="ACL8JK_000785"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1785703.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6297..6623
                     /locus_tag="ACL8JK_000786"
                     /pseudo
     CDS             6297..6623
                     /locus_tag="ACL8JK_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035616.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(6924..8035)
                     /gene="ald"
                     /locus_tag="ACL8JK_000787"
                     /pseudo
     CDS             complement(6924..8035)
                     /gene="ald"
                     /locus_tag="ACL8JK_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            8212..8635
                     /locus_tag="ACL8JK_000788"
                     /pseudo
     CDS             8212..8635
                     /locus_tag="ACL8JK_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8703..9353
                     /locus_tag="ACL8JK_000789"
     CDS             8703..9353
                     /locus_tag="ACL8JK_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGS1785704.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            9337..11577
                     /locus_tag="ACL8JK_000790"
     CDS             9337..11577
                     /locus_tag="ACL8JK_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGS1785705.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSTSYLALLGFVFLLVCL
                     FFQFPWKSASKVLVICGIFGFWFVFQNWQQSQASQNLADSVEGVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPGPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLIAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            11756..11944
                     /locus_tag="ACL8JK_000791"
     CDS             11756..11944
                     /locus_tag="ACL8JK_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785706.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYGRYEVINYYSGGY"
     gene            11976..12563
                     /locus_tag="ACL8JK_000792"
     CDS             11976..12563
                     /locus_tag="ACL8JK_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1785707.1"
                     /translation="MLNITHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNISAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            12567..13747
                     /locus_tag="ACL8JK_000793"
                     /pseudo
     CDS             12567..13747
                     /locus_tag="ACL8JK_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     misc_feature    13907..14038
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14054..14584
                     /gene="infC"
                     /locus_tag="ACL8JK_000794"
     CDS             14054..14584
                     /gene="infC"
                     /locus_tag="ACL8JK_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGS1785708.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14617..14817
                     /gene="rpmI"
                     /locus_tag="ACL8JK_000795"
     CDS             14617..14817
                     /gene="rpmI"
                     /locus_tag="ACL8JK_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGS1785709.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            14869..15228
                     /gene="rplT"
                     /locus_tag="ACL8JK_000796"
     CDS             14869..15228
                     /gene="rplT"
                     /locus_tag="ACL8JK_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGS1785710.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15286..15666
                     /locus_tag="ACL8JK_000797"
     CDS             15286..15666
                     /locus_tag="ACL8JK_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS1785711.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            15916..16716
                     /locus_tag="ACL8JK_000798"
     CDS             15916..16716
                     /locus_tag="ACL8JK_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGS1785712.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            16727..17665
                     /locus_tag="ACL8JK_000799"
     CDS             16727..17665
                     /locus_tag="ACL8JK_000799"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGS1785713.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFVFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17707..19740
                     /locus_tag="ACL8JK_000800"
     CDS             17707..19740
                     /locus_tag="ACL8JK_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGS1785714.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYADNEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGVFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(19801..21456)
                     /gene="pavA"
                     /locus_tag="ACL8JK_000801"
     CDS             complement(19801..21456)
                     /gene="pavA"
                     /locus_tag="ACL8JK_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HGS1785715.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21561..22058
                     /gene="ybeY"
                     /locus_tag="ACL8JK_000802"
     CDS             21561..22058
                     /gene="ybeY"
                     /locus_tag="ACL8JK_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGS1785716.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAKKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22039..22434
                     /locus_tag="ACL8JK_000803"
     CDS             22039..22434
                     /locus_tag="ACL8JK_000803"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGS1785717.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22451..23350
                     /gene="era"
                     /locus_tag="ACL8JK_000804"
     CDS             22451..23350
                     /gene="era"
                     /locus_tag="ACL8JK_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGS1785718.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23399..24223
                     /gene="mutM"
                     /locus_tag="ACL8JK_000805"
     CDS             23399..24223
                     /gene="mutM"
                     /locus_tag="ACL8JK_000805"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGS1785719.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24223..24828
                     /gene="coaE"
                     /locus_tag="ACL8JK_000806"
     CDS             24223..24828
                     /gene="coaE"
                     /locus_tag="ACL8JK_000806"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGS1785720.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKSGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            24815..26014
                     /locus_tag="ACL8JK_000807"
     CDS             24815..26014
                     /locus_tag="ACL8JK_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HGS1785721.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYLVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26014..26163
                     /gene="rpmG"
                     /locus_tag="ACL8JK_000808"
     CDS             26014..26163
                     /gene="rpmG"
                     /locus_tag="ACL8JK_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS1785722.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26203..26436
                     /gene="secG"
                     /locus_tag="ACL8JK_000809"
     CDS             26203..26436
                     /gene="secG"
                     /locus_tag="ACL8JK_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGS1785723.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26538..28892
                     /gene="rnr"
                     /locus_tag="ACL8JK_000810"
     CDS             26538..28892
                     /gene="rnr"
                     /locus_tag="ACL8JK_000810"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGS1785724.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTIIQTVIKTSFRMTYSDVNDILAVDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            28855..29322
                     /gene="smpB"
                     /locus_tag="ACL8JK_000811"
     CDS             28855..29322
                     /gene="smpB"
                     /locus_tag="ACL8JK_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGS1785725.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29338..30198
                     /gene="tehB"
                     /locus_tag="ACL8JK_000812"
     CDS             29338..30198
                     /gene="tehB"
                     /locus_tag="ACL8JK_000812"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HGS1785726.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30271..31224
                     /gene="coiA"
                     /locus_tag="ACL8JK_000813"
     CDS             30271..31224
                     /gene="coiA"
                     /locus_tag="ACL8JK_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HGS1785727.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQIHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHIANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGKKLWLKERLTCLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIK
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            31243..33045
                     /gene="pepF"
                     /locus_tag="ACL8JK_000814"
     CDS             31243..33045
                     /gene="pepF"
                     /locus_tag="ACL8JK_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGS1785728.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYAYLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            33047..33760
                     /locus_tag="ACL8JK_000815"
     CDS             33047..33760
                     /locus_tag="ACL8JK_000815"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGS1785729.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            33827..34768
                     /gene="prsA"
                     /locus_tag="ACL8JK_000816"
     CDS             33827..34768
                     /gene="prsA"
                     /locus_tag="ACL8JK_000816"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HGS1785730.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(34887..35228)
                     /locus_tag="ACL8JK_000817"
                     /pseudo
     CDS             complement(34887..35228)
                     /locus_tag="ACL8JK_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            35647..35742
                     /locus_tag="ACL8JK_000818"
                     /pseudo
     CDS             35647..35742
                     /locus_tag="ACL8JK_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(35995..36615)
                     /locus_tag="ACL8JK_000819"
     CDS             complement(35995..36615)
                     /locus_tag="ACL8JK_000819"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS1785731.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPGSIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(36615..37097)
                     /locus_tag="ACL8JK_000820"
     CDS             complement(36615..37097)
                     /locus_tag="ACL8JK_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGS1785732.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKMSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(37097..37939)
                     /locus_tag="ACL8JK_000821"
     CDS             complement(37097..37939)
                     /locus_tag="ACL8JK_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGS1785733.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(38034..38834)
                     /locus_tag="ACL8JK_000822"
     CDS             complement(38034..38834)
                     /locus_tag="ACL8JK_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HGS1785734.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPFYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            38978..40357
                     /gene="glmU"
                     /locus_tag="ACL8JK_000823"
     CDS             38978..40357
                     /gene="glmU"
                     /locus_tag="ACL8JK_000823"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGS1785735.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVILKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVIVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGNNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            40367..40912
                     /locus_tag="ACL8JK_000824"
     CDS             40367..40912
                     /locus_tag="ACL8JK_000824"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS1785736.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            40924..41238
                     /gene="macP"
                     /locus_tag="ACL8JK_000825"
     CDS             40924..41238
                     /gene="macP"
                     /locus_tag="ACL8JK_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGS1785737.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            41255..41947
                     /locus_tag="ACL8JK_000826"
     CDS             41255..41947
                     /locus_tag="ACL8JK_000826"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGS1785738.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            42024..42515
                     /gene="rocS"
                     /locus_tag="ACL8JK_000827"
     CDS             42024..42515
                     /gene="rocS"
                     /locus_tag="ACL8JK_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HGS1785739.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            42613..43203
                     /locus_tag="ACL8JK_000828"
     CDS             42613..43203
                     /locus_tag="ACL8JK_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGS1785740.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            43212..44846
                     /locus_tag="ACL8JK_000829"
                     /pseudo
     CDS             43212..44846
                     /locus_tag="ACL8JK_000829"
                     /inference="COORDINATES: protein motif:HMM:NF021615.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
BASE COUNT        13622 a         8232 c        10021 g        13147 t
ORIGIN      
        1 aagttgcttt cgtgaatacc aaaatcagcc gcaatttgtt cataagttcg atattctcgc
       61 acatattgaa gagtggccat aagaaggtct tctaggctta atttaggttt tcgtccacct
      121 tttgcgtgtt taagttgata agctgttttt aatacagcta atatctcttc aaaagtcgtg
      181 cgctgaacac caacaagacg cttaaatcgt gcatcagtta gttgtttact tgcttcatca
      241 ttcatagaac tactatacca tattttgttt cgcaggaagt ctattggaaa gtaagaaata
      301 ttgaagctga ggctattaga agaaattgtg agcgtggtgc tattttttca ggtaaaataa
      361 aatatcacga agattcacag tttaaaggag atcactatgt tgaatgttat gctgttttag
      421 ataatacggt tatagcaaga gatagaataa cagtccctat cgatccgtta tgtggaaaag
      481 attttataga gtagcatata attgattctt aactggaata ctcactatct ctttacatca
      541 agaaaatgac taaacaggga agtttgcctt cttccctttt tttgttatac tagtagaaga
      601 aaaaattaga aagatttgtg ggtgtcaaac agcccagtgg ggtgttttaa tatggactta
      661 ggtcccaccc aaagaggtat tagtgtcgtg tctcaatctt atatcaatgt tatcggtgct
      721 ggtttggcag gttctgaagc agcttaccaa atcgcagagc gtggtattcc agttaaacta
      781 tatgaaatgc gtggtgtcaa gtctacaccc cagcataaaa cagacaattt tgctgagttg
      841 gtttgttcca attctttgcg tggggatgct ttgacaaatg cagttggtct tctcaaggaa
      901 gaaatgcgtc gcttgggttc tgttatcttg gaatctgctg aggctacacg tgttcctgca
      961 ggtggtgccc ttgcagtgga ccgtgatggt ttctctcaaa tggtgaccga aaaagttgcc
     1021 aaccacccct tgattgaagt ggttcgtgat gaaattacag aattgccgac agatgttatt
     1081 acggttatcg ctactggtcc tttgacaagt gatgccttgg ctgaaaagat tcatgccctt
     1141 aataatggcg atggcttcta tttctacgat gcagcagcgc ctattatcga tgtcaacact
     1201 atcgatatga gtaaggtcta tctcaaatct cgttatgata agggagaagc agcctatctc
     1261 aatgctccaa tgaccaagca agagtttatg gatttccatg aagccttggt caatgcggaa
     1321 gaagcaccgc tcaattcttt tgaaaaagaa aagtactttg aaggatgtat gccaatcgaa
     1381 gttatggcca aacgtggcat taaaactatg ctttatggcc ctatgaagcc agtcggtctt
     1441 gagtatccgg acgactacac aggacctcgt gatggagaat ttaaaacacc ttatgcggtt
     1501 gtgcaacttc gtcaggataa tgcagctggt agcctataca atattgttgg tttccagacc
     1561 cacctcaaat ggggagaaca aaagcgtgtc ttccaaatga ttccgggtct tgaaaatgcg
     1621 gagtttgtcc gttatggtgt catgcatcgc aattcttaca tggattcacc aaatcttctt
     1681 gagcagactt accgttccaa gaaacaacca aatctcttct ttgctggtca gatgacgggg
     1741 gtggaaggct atgttgagtc ggcggcttcg ggcttagttg cgggaattaa cgcagctcgt
     1801 ctcttcaagg aagaaagcga ggttattttc cccgagacga cagcgattgg aagcttagct
     1861 cattacatta cccatgccga cagcaaacat ttccaaccaa tgaatgtcaa ttttgggatc
     1921 atcaaggagt tggaaggcga gcgtatccgt gataagaagg ctcgttatga aaaaattgca
     1981 gagcgtgccc ttgccgactt agaggaattt ttgactgtct aatttttttg aaagaattgt
     2041 tcatgatact ataaaaatct tagaaattgt gataaaatag gtaggatgaa agaaggagag
     2101 tgaaaatggc gaatcccaag tataaacgta ttttaatcaa gttatcaggt gaagcccttg
     2161 ccggtgaacg tggcgtaggg attgatatcc aaacagttca aacaatcgca aaagagattc
     2221 aagaagttca tagcttaggt atcgaaattg cccttgttat tggtggagga aatctctggc
     2281 gtggagaacc tgcagcagaa gcaggtatgg accgtgttca ggcagattac actggaatgc
     2341 ttgggactgt tatgaatgct cttgtgatgg cagattcatt gcaacaagtt ggggttgata
     2401 cgcgtgtaca aacagctatt gctatgcaac aagtggcaga gccttatgtc cgtggacgtg
     2461 cccttcgtca ccttgaaaaa ggccgtatcg ttatctttgg tgctggaatt ggttcaccat
     2521 acttctcgac agatacaaca gcggcccttc gtgcagctga aatcgaagca gatgccatcc
     2581 tcatggctaa aaatggcgtc gatggtgtgt acaatgccga tcctaagaag gacaagacag
     2641 ccgttaagtt tgaagaattg acccaccgtg atgttatcaa caaaggtctt cgtatcatgg
     2701 actcaacagc ctcaaccctc tcaatggaca acgacattga cttggttgtc ttcaacatga
     2761 accaatcagg caacatcaaa cgtgtcgtat ttggtgaaaa tatcggaaca acagtttcaa
     2821 ataatatcga agaaaaggaa taagaaagaa tatggctaac gtaattattg aaaaagctaa
     2881 agagagaatg acccagtctc accaatcact tgctcgtgaa tttggtggta tccgtgctgg
     2941 tcgtgccaat gcaagcttgc ttgaccgtgt acatgtagaa tactatggag tcgaaactcc
     3001 tcttaaccaa atcgcttcaa ttacgattcc agaagcgcgt gttttgttgg taacaccatt
     3061 tgacaagtct tcattgaaag acatcgaacg tgccttgaac gcttctgatc ttggtatcac
     3121 accggctaat gacggttctg tgattcgctt ggttatccca gctcttacag aagaaactcg
     3181 tcgtgacctt gctaaagaag tgaagaaggt cggcgaaaat gctaaagtgg ctgtccgcaa
     3241 tatccgtcgc gatgctatgg acgaagctaa gaaacaagaa aaagcaaaag aaatcactga
     3301 agacgaattg aagactcttg aaaaagacat tcaaaaagta acagacgatg ctgttaaaca
     3361 catcgacgac atgactgcta acaaagagaa agaacttttg gaagtctaaa aataaacaga
     3421 aaaactcagt tggcattgct ggctgagttt tattcgaaag aaggaaatat gaatacaaat
     3481 cttgcaagtt ttatcgttgg actgatcatc gatgaaaacg accgttttta ctttgtgcaa
     3541 aaggatggtc aaacctatgc tcttgctaag gaagaaggcc aacatacagt aggggatacg
     3601 gtcaaaggtt ttgcatacac ggatatgaag caaaaattcc gcctgacaac cttagaagtg
     3661 actgccactc aggaccaatt tggttgggga cgtgtcacag aggttcgtaa ggacttgggt
     3721 gtctttgtgg atacaggcct tcctgacaag gaaatcgttg tgtcactcga tattctccct
     3781 gagctcaagg aactctggcc taagaagggc gaccaactct acatccgtct tgaagtagat
     3841 aagaaagacc gtatctgggg cctcttggct tatcaagaag acttccaacg tcttgctcgt
     3901 cctgcttaca acaacatgca gaaccaaaac tggccagcca ttgtttaccg tctcaagctg
     3961 tcaggaactt ttgtttacct accagaaaat aatatgcttg gttttattca tcctagcgag
     4021 cgttacgcag agccacgttt ggggcaagta ttagatgcgc gcgttattgg tttccgtgaa
     4081 gtggaccgca ctctgaacct ctccctcaaa ccacgctcct ttgaaatgtt ggaaaacgat
     4141 gctcagatga ttttgactta tttggaaagc aatggcggtt tcatgacctt aaatgacaag
     4201 tcatctccag acgacatcaa ggcaaccttt ggcatttcta aaggtcagtt caagaaagct
     4261 ttaggtggtc ttatgaaggc tggtaaaatc aagcaagacc agtttgggac agagttgatt
     4321 tagggaggct tatgagaaaa tcattttaca cttggctcat gaccgagcgc aatcctaaaa
     4381 gtaacagtcc caaagcaatt ttggcagacc tcgcttttga agaggcagct tttccaaaac
     4441 atacagatga ttttgatgag gtcagtcgct ttttggagga gcatgccagt ttctctttta
     4501 acctaggaga ttttgacagc atttggcagg aatatctaga acactagcat ttattcattg
     4561 ggtttgggct agtaatttct ccatccctct gctataataa aaagaaataa aaggattaga
     4621 gaggttcttt atttgaagga acattcaata gacattcaac tgagtcatcc agatgacctg
     4681 tttcatcttt ttggttccaa tgaacgccat cttcgtttga tggaagaaga gcttgatgtt
     4741 gtgattcatg ctcgtacgga gattgtccag gttttgggag aagagtctgc ctgtgaggaa
     4801 gcccgtcaag ttattcaggc tttgatggtc ttggtaaatc gtgggatgac cgttggtacg
     4861 ccagatgtag tcactgcgat tagcatggtc aaaaacgatg aaattgataa gtttgtcgcc
     4921 ctttacgaag aagaaattat caaggataat actgggaaac cgatccgcgt caaaacctta
     4981 ggtcaaaaac tttatgtgga cagtgtcaaa cagcatgatg tgacctttgg aattgggcct
     5041 gcagggacgg ggaagacctt tcttgcagtt actttggcag tgactgccct taaacgtggg
     5101 caagtcaagc ggattatctt gacacgtcca gcggtggaag caggagagag tctaggtttt
     5161 cttccgggtg atcttaagga gaaggtagat ccttaccttc gtcctgttta cgatgccttg
     5221 tatcagattc tggggaaaga ccaaacgact cgtctcatgg agcgtgaaat tatcgaaatt
     5281 gcgccccttg cctatatgcg tggtcggacc ttggatgatg cctttgtcat tctcgatgag
     5341 gcgcaaaaca cgaccatcat gcagatgaag atgttcttga cgcgtttagg ctttcattct
     5401 aagatgattg tcaatggaga tatcagtcag attgacctgc cacgcaatgt caagtcaggt
     5461 ttgattgatg cccaagagaa actcaagaac atccatcaga ttgactttgt tcatttttca
     5521 gctaaggatg tggttcgcca tccagttgtc gctcagatta tccgagctta tgaatattct
     5581 actgaagttg cacacgactg attttgagga agttcgcctg caaaagaata tacttttgag
     5641 agaggaaaat ccagttgtat aggctaaagg ttttatccaa aggtttgaga caacgattag
     5701 gcacgatgga aagaactttt atgtggctga tgacgatcag tgcatcttcc tgtgtcataa
     5761 tcacagggca caagaaagta ggaatttgaa aagatgattg accaactatc taagtattac
     5821 agttgtagga tactaactga aaaggatatt ccaagtattt tatctttata tgaaagtaat
     5881 cctctgtatt ttcagcattg tccaccagaa ccaaattttg caactgtaaa agaggacatg
     5941 ctttgtctac ctgaaggtaa agctaaggct gataagtttt ttgttggatt ttggaatgga
     6001 tctgaccttg tggctgttat ggattttgtc tatgcatatc ctgatgagga gactgttttt
     6061 attggtttgt ttatggttga tcaagcctat cagaggaaag ggattggtag tcatattgtg
     6121 acagaagcac tagcttattt tgctaagaac tttcgaaagg cacgtttggc ttatgttaag
     6181 ggaaatccgc aatctcagca tttttgggaa aagcagggct ttaaatcaat tggatgcgag
     6241 gttaagcaag aactctatac ggttgttatc gctgaacaga gcctagaaga ttagaaatgg
     6301 catcaagtaa gaactatttg gaatttgttt tggaacaatt atcaggatta gatgatgtga
     6361 cttaccgttc catgatgggg gagtatattc tttacttccg cggcaagatt attggcggca
     6421 tttatgacga tcgcttttta gttaaacccg tgcaagcagt cttagataag attgaccaat
     6481 cttcttttga gtttccatac aaaggtgcca aagaaatgat ttgagtggaa gaacttgata
     6541 ataagatgtt tctataagac ctgattttag ctatgtataa ccaactgcca acgcccaaac
     6601 ctaaaaagaa aaagcaagtg tgaacgaagt aaaaaagaag tctgctaagg ccctgtcttt
     6661 gcacgggtaa aattttatat ataaaaagaa gctgggacta aagagctcag cttcctttgg
     6721 tttatataat tgtcattaca agacgaagtg gttgggcgaa actctgttga ctttattcaa
     6781 tttagagttt cttatgcacg attgagtctg gaacgaaagt ctccagttgc aaagtataca
     6841 gtacaataaa ccaacgatgt aatagctgat gacacaaagc acagtgggta ggacttgcga
     6901 agtcaccctt ttcttttcaa aatttatact aaatcattga tatcagtgta gtcacgatta
     6961 agtccttgag caactggtag gctagtcaag taaccttgat aagtggtcac accttgacgc
     7021 aagccttcat cttcagagat tgcttgtgcg aatcctttgc cagccaaagc ttcgatataa
     7081 ggaagagtga cattggttag ggcgatggtt gaagtgtggg caaccgcacc agggatattg
     7141 gcaacggcat agtggagaac accgtgtttt tcatagacgg gttcatcgtg cgttgtcaca
     7201 cggtcagctg tttcgataag gccaccttgg tcaacagcaa cgtcaacgat acagagcctg
     7261 gacgcatttg tttgaccatc tcatctgtca ccaattccgg tgcttttgca ccagggatga
     7321 gaatggctcc aatcaccaca tcagcatctc tcacacttgc ttcaatgttg aatgaattag
     7381 atataagagt ttgaatttga cttccaaaga cttcttctag aactgagaga cgcttggcac
     7441 taatatctaa aatagtcact tgagcaccaa gaccaagggc gatgcgggca gcatgtgtac
     7501 cgacgacacc atcaccgatg atagttactt ttccttttgg aacacctggt acaccaccag
     7561 gtagaacacc agagccacca gcttgcttag taaggaagtg agctccgatt taaacagcca
     7621 tacgacctgc aacctcactc ataggaacga ggagcggtag ttgtccttga ttgtcacgaa
     7681 cagtttcata ggcaattcct gttgtttttg ctgctaacat agcatctgct aattctggag
     7741 cagcggccat gtgcaagtag gtgaagagaa gaagatcgtc gcgcaagtaa ccgtattcag
     7801 aacttaaagg ttcttttact ttcacaacca actctgctac ccaagcttca ccagcagtag
     7861 cgacaatctc agctccttgc ttttgatagt cagcatcagt aaagccagaa ccgagaccag
     7921 catttgtttc gataaggaca cgatgaccac gactaactaa gctatgaaca cctgcaggtg
     7981 tgagggcgac acggttttcg ttatttttaa tttcttttgg gattccgatt aacattgaga
     8041 taacctacct ttcaattgac ggtcttgttt tggttgtcac attccagttc ataaatcaaa
     8101 aatgtgacgg tttcattgta tatgaaaccg cttcaaaaat caagaaaaac ttgtcatccc
     8161 aattttttta tgctagacta gtgaaaatca agctctaatg gagggaaaag tatggaatca
     8221 atttttgtaa aacttgccca gtatccgtct atagaaacgg agcgtttatt gcttagacct
     8281 gtaactttgg atgatgcgga agcaatgttt gactatgcct cggacaaggg taatacacgt
     8341 tacacttttc caaccaatca aagcttggaa gaaaccaaga ataacattgc tcagttctac
     8401 ttggctaatc ccttgggacg ttggggaata gaactaaaaa gcaatggtca gtttattgga
     8461 accattgact tgcacaagta aggctaatcc cgcgtcagga aaggtcatgg agaaatcagg
     8521 catgcgtttt tcccatgcag aaccatatgc ttgtatggac cagcatgaaa aaggccgaat
     8581 cgtgacaaga gttcattatg tcttgaccaa ggaagactat tttgcaaata aataagcagt
     8641 tgaaaagaaa tttttcgact gttttttctt cctcttacga ataatctaag agaggagaaa
     8701 atatggaagc aattatcgag aaaatcaaag agtataaaat catcgtcatc tgtactggtc
     8761 tgggcttgct tgtaggagga tttttcctgc taaagccagc tccacaaaca cctgtcaaag
     8821 agacgaattt gcaggctgaa gttgcagctg tttccaagga ctcatcgacc ggaaaggaag
     8881 tgaacaagga agagaaggaa gaaccagttg aacaagatct aatcacagta gatgtcaaag
     8941 gtgctgtcaa atcgccaggg atttatgact tgcctgtagg tagtcgagtc aatgatgctg
     9001 ttcagaaggc tggtggcttg acagagcaag cagacagcaa gtcgctcaat ctagctcaga
     9061 aagttagtga tgaggctctg gtttacgttc ctactaaggg agaagaagca gttagtcaac
     9121 agactggttc ggggacagct tcttcaacaa gcaaggaaaa gaaggtcaat ctcaacaagg
     9181 ccagtctgga agaactcaag caggtcaagg gactgggagg aaaacgagct caggacatta
     9241 ttgaccatcg tgaggcaaat ggcaagttca agtcagtaga cgagctcaag aaggtctctg
     9301 gcattggtgc caagactata gaaaagttaa aagactatgt tacagtggat taagaatttc
     9361 tctattcccc taatttacct gagttttctg ttactttggc tttactacgc cattttttca
     9421 acatcctatc ttgctttgtt gggatttgtt tttctgctag tctgtctctt tttccaattt
     9481 ccttggaaat ctgctagcaa agttctagtg atttgtggaa tctttggatt ttggtttgtt
     9541 tttcaaaatt ggcaacagag tcaagcgagt caaaatctgg cggattctgt tgaaggggta
     9601 cggattttgc ctgatactat taaggttaat ggtgatagtc tatcctttcg tggcaagtct
     9661 aacggtcgtg ctttccaagt ctattataaa ctccagtccg aggaggagaa agaagccttt
     9721 caagctttaa ccgacctgca tgagatagga ctagaaggga agctttcgga gccagaaggg
     9781 cagagaaatt ttggtggctt taattaccaa gcctatctga agactcaggg aatttaccag
     9841 actctcaata tcaaaacaat ccagtcactt caaaagattg gcagttggga tataggagaa
     9901 aacttgtcca gtttacgtcg aaaggctgtg gtttggatta agacgcactt tccaggccct
     9961 atgcgcaatt acatgacagg actcttgctg ggacatctgg acaccgactt tgaggagatg
    10021 aatgagcttt attccagtct aggaattatc cacctctttg ccctatctgg catgcaggta
    10081 ggttttttca tgaatggatt taagaaactt ctcttgcgat tgggcttgac ccaagaaaag
    10141 ttgaaatggc tgacttatcc cttttccctt atctatgcgg gactaactgg attttcagca
    10201 tcggttattc gcagtctctt gcaaaagcta ctggctcaac atggggttaa gggcttggat
    10261 aattttgcct tgacggtgct tgtcctcttt attgtcatgc caaacttttt cttgatagca
    10321 ggaggagtct tgtcctgcgc ttatgctttt atcctgacca tgaccagcaa agaaggggag
    10381 gggctcaagg ctgttgctag tgaaagtcta gtcatctcct tgggcatatt gcccattcta
    10441 tccttctatt ttgcggaatt tcaaccttgg tctatccttt tgacctttgt cttttccttt
    10501 ctatttgact tgaccttctt accgctcttg tctattttat ttgtcctttc ctttctctat
    10561 ccagtcattc agctgaactt tatctttgaa tggttagagg gcattattcg cttggtctcg
    10621 caggtggcaa ggagaccgct tgtctttggt caacccaacg catggctttt aatcttattg
    10681 ttaatttcct tggctttggt ctatgatttg aggaaaaaca ttaaaggatt aacagtattg
    10741 agtttattga ttacaggtct ctttttcctt accaagtatc cactggaaaa tgaaatcacc
    10801 atgctggatg tggggcaagg agaaagtatt ttcctacggg atgtaactgg gaaaaccatt
    10861 ctcatagatg taggtggtaa ggcagaatct tataagaaaa tcgaaaaatg gcaagaaaag
    10921 atgacgacca gcaatgccca gcgaaccttg attccctatc tcaaaagtcg aggagtagct
    10981 aagattgacc agctaatttt gactaacacg gacaaggaga atgttggaga tttgtcagag
    11041 gtgaccaagg ctttccatgt aggggagatt ctagtatcaa aagacagtct gaaacagaag
    11101 gaatttgtgg cagaactaca ggcgactcaa acaaaggtgc gtagtatgac agtaggggag
    11161 aacttgccca tttttggaag tcagttagaa gttctatctc caaggaaaat gggagatgga
    11221 ggacacgatg ataccctagt tctgtatggg aaattcttgg ataagcaatt tctcttcacg
    11281 ggaaatttgg aggagaaagg agagaaggac ttgctgaagc actatccaga cttgaaagta
    11341 aatgttttga aagctagcca acatggcaat aaaaaatcat caagtccagc ctttctagaa
    11401 aaactcaaac cagagcttac tcttatctca gttggaaaga gcaatcgaat gaaactcccc
    11461 catcaggaaa cattgacacg actggaaggt atcaatagca aagtttatcg aactgaccag
    11521 caaggagcta tacgttttaa ggggttggat agttggaaaa tcgaaagtgt tcgataggaa
    11581 ggataaatgt tgtagattag tgaaataaac taaaaatttg ttgcataata atgataaaaa
    11641 tggtataatg aaaacgtatt caatattgag gatgtaaaat cattaaaaat tagcaaaaat
    11701 cgtttaatta gttagtttat aatctattgg tcttcttcag tccagtgtat ctgctgtgac
    11761 agtcactaaa agttacaagt atgattggaa tacggtttgg gaatatagta ccaactatca
    11821 cgaccatcag tatgcttgga ttccgtcatg gtctcgttat gacagctatt ctgagtataa
    11881 agttggcgga ggctggaact acggtcgtta tgaggtcata aactattaca gcggaggcta
    11941 ttaatcctta aagagtgaga aaaggagggc tggatatgtt aaatattact catgttacct
    12001 taaaaacgcg acaagtcatc ttgcaagatg tggatttcac ctttaaaaag ggtagggttt
    12061 atggtcttct tgctatcaat ggctctggaa agacgaccct gttccgtgcc attagcaatt
    12121 taattcccat aagtagtgga aatatctcag cccctccttc tttattttat tatgagagta
    12181 ttgaatggct ggatggaaac ttaagtggga tggactacct tcgtcttatc aaaaacatct
    12241 ggaagtcagg tctgaacttg agggatgaaa tcgcctattg ggaaatgtct gactatatca
    12301 gtcttcccat tcgcaagtat tccttaggca tgaagcaacg cttggtgatt gccatgtatt
    12361 tcctcagtca ggccaaatgc tggctcatgg atgagattac aaatggctta gatgagtatt
    12421 atcgacagaa gttttttgat aggttagcac aaatcgatag acaagaacag ctggttcttt
    12481 taagttccca ctataaggaa gagttggttg atatctgcga tagagtagta accattcatc
    12541 aggggcagat agaagaggtt tagtttatga aagatgttag tctattttta ttgaaaaaag
    12601 ttttcaaaag ccgcttaaac tggattatct tagctttatt tgtatctgta ctcggtgtta
    12661 ctttttattt taatagtcag actgcaaact cagtcagctt ggagagagag ttggaaactc
    12721 gtcttgtaga ccgtgagaga gtcatcaatg aatatgaaga gaaactctcc caaatgtctg
    12781 ataccagctc ggaggaatac cagtttgcta aaaataattt agacgtgcaa aaaaatcttt
    12841 tgacgcgaaa gacagaaatt ctaactttac taaaagaagg gcgctggaaa gaggcctact
    12901 atctgcagtg gcaagatgaa gagaaagatt atgaatttgt atcaaatgac ccgactgcta
    12961 gctctgaatt aaaaatgggg gttgaccgcg aacggaagat ttatcaagcc ctgtatccct
    13021 tgaacataaa agcacatact ttggagtttc cgacccacgg gattgatcag attgtctgga
    13081 ttttagaggt tatcatccca agcttgtttg tggttgcgat tatttttatg ctaacacaac
    13141 tatttgcaga aagatatcaa aatcatctgg acacagctca cttatatcct gtttcaaaag
    13201 tgacatttgc aatatcctct cttggagttg gagtgggata tgtaactgtg ctgtttatcg
    13261 gaatctgtgg cttttctttt ctagtgggaa gtctgataag tggttttgga cagttagatt
    13321 atccctaccc aatttatagc ttagtgaatc aagaagtaac tattgggaaa atacaagatg
    13381 tattatttcc tggcttgctc ttagctttct tagcctttat cgtcattgtg gaagttgtgt
    13441 acttgattgc ttactttttc aagcaaaaaa tgcctgtcct ctttctttca ctcattggga
    13501 ttgttggctt attgtttggc atccaaacaa taagcctctt caaaggattg cacatctgat
    13561 tccctttact tacttgcgtt cagtggagat tttatctgga agattatcta agcagattga
    13621 taatgtcgat ctaaattgga gcatggggat ggtcttactt ccttgcctga ttatcctttt
    13681 gttagtgggg attctattta tcgaaagatg gggaagttca cgtaaaaagg aagtttttaa
    13741 agtttagttt tcctataggg aagctaaaga aaaactaaca tagggagaga atcaacttgg
    13801 ttctctcttt ttgattcgaa aaccaaacca aaatacaaac acaaactttt caaaaaataa
    13861 ctttttatct tgacaagagc tagaaaactt ggtatcatat aaaagttgag aaaagcagaa
    13921 gtgagagctt ctcgccttgt gacattaagt tgcctggccc tacggatgaa aagtttcgaa
    13981 gaaacgctat cataacgtgc gggcttgtat atttacgagt ccgctattgt ttttctctaa
    14041 taaaacaaaa gaggtgaaaa ccatagcaaa gcaagactta ttcatcaatg atgagattcg
    14101 tgtacgtgaa gttcgcttga ttggtcttga gggagaacag ctaggcatca agccactcag
    14161 tgaagcgcaa gctttggctg ataacgctaa tgttgaccta gtattgattc aaccccaagc
    14221 caaaccgcct gttgcaaaaa ttatggacta cggtaagttc aaatttgagt accagaagaa
    14281 gcaaaaagaa caacgtaaaa aacaaagcgt tgttactgtg aaagaagttc gtctaagtcc
    14341 aacaattgac aagggtgact ttgatacaaa acttcgtaat gcacgtaagt tccttgaaaa
    14401 aggaaataaa gttaaggtat ctattcgctt taagggtcgt atgattaccc ataaagagat
    14461 tggtgcaaaa gttttagccg agtttgctga agcaactcaa gatattgcca tcatcgaaca
    14521 acgtgctaaa atggatggac gtcaaatgtt catgcaattg gcgccagcga ctgacaaaaa
    14581 ataattgtca gaaagttaaa taaaggagaa aaaatcatgc caaaacaaaa aacacaccgc
    14641 gcatcagcta aacgtttcaa acgtacaggt tctggtggac ttaaacgttt ccgtgcttac
    14701 acttctcacc gtttccacgg aaaaactaag aaacaacgtc gtcatcttcg taaagcatct
    14761 atggtgcatt caggagatta caaacgtatc aaagcaatgc ttactcgctt gaaataatag
    14821 cttgactgta agtaaacaat tctaggaaat atttggagga aataaaacat ggcacgtgtt
    14881 aaaggtggcg ttgtatcacg caaacgtcgt aaacgtattc ttaaattagc aaaaggttac
    14941 tatggagcta aacacatctt gttccgtact gcaaaagaac aagtaatgaa ctcttactac
    15001 tatgcatacc gtgaccgtcg tcagaaaaaa cgtgacttcc gcaaattgtg gattactcgt
    15061 atcaatgcgg cagctcgtat gaacggactt tcatactcac aattgatgca tggtttgaaa
    15121 ttggctgaga tcgaagttaa ccgtaaaatg cttgctgact tggctgttaa cgatgcagta
    15181 gctttcacag ctcttgcaga tgcagctaaa gcaaaacttg gtaaataaca actgatgaga
    15241 ctggaacagg attgtccagt ctttttaaaa ataaaggaga aagatatggc ttcaaaaatg
    15301 ctacacactt gcttacgagt agaaaatctt gaaaaatcaa tcgcatttta tcaagatgct
    15361 tttggtttta aagaattgcg tcgcagagat tttccagacc atgccttcac gattgtctat
    15421 ctaggtcttg agggtgatga ttatgagttg gagttgactt ataactacga tcacggtccg
    15481 tatgtggttg gtgatgggtt tgcccatatc gccctcagta cacctgatct tgaggcactt
    15541 catcaagaac acagtgcaaa aggctatgaa gtgactgagc caaatggtct accaggaact
    15601 acaccaaact attactttgt taaagaccct gatggatata aggtcgaagt cattcgtgaa
    15661 aaataatttc gtgcaagtta agtagaatat tcgttttcta cttgactttt tttagctgaa
    15721 agagtatact aataaaaatt caacctttaa ggggagtcca gagagactca caaggtgtca
    15781 gataaaagaa tagtgcaatt ttctagagga gaccttttga gtgtgctctc ttgtgttgta
    15841 cgattttaac tgaggccttg cactagcaag gtcttttctt tatctggtcc ccttaaaatt
    15901 taaggaggaa aagttatgaa tctcacatgt aagaagcgtt tgggtgtcat tcggttggaa
    15961 accatgaagg tggttgcaca agaggaaatc gcgccagcaa tctttgaatt agtcctagaa
    16021 ggagaaatgg ttgaagccat gcgagcaggc caatttcttc atctgcgtgt accagacgat
    16081 gcccatctct tacgtcgtcc tatttcaatt tcgtctattg acaaggcaaa caagcagtgt
    16141 cacctcattt atcggattga gggagctggg actgcaattt tttcaacctt aagtcaggga
    16201 gacactcttg atgtgatggg gcctcaggga aatggttttg acttgtctga ccttgatgag
    16261 cagaatcagg ttctccttgt tggtggtggg attggtgttc cacccttgct tgaggtggcc
    16321 aaggaattgc atgaacgtgg agtgaaagta gtgacagtcc tcggttttgc taataaggat
    16381 gctgttattt tgaaaacgga attggctcag tatggtcagg tctttgtaac gacagatgat
    16441 ggttcttatg gcatcaaggg aaatgtttcc gttgttatca atgatttaga tagtcagttt
    16501 gatgctgttt actcgtgtgg ggctccagga atgatgaagt atatcaatca aacctttgat
    16561 gatcacccaa gagcctattt atctctggaa tctcgtatgg cttgtgggat gggagcttgc
    16621 tatgcctgtg ttctaaaagt accagaaagc gagacggtca gccaacgcgt ctgtgaagat
    16681 ggtcctgttt tccgcacagg aacagttgta ttataaggag aaaattatga ctacaaatcg
    16741 attacaagtg tctctacctg gtttggattt gaaaaatccg attattccag catcaggctg
    16801 ttttgtcttt ggacaagagt atgccaagta ctatgattta gaccttttag gttctattat
    16861 gatcaaggcg acaacccttg aaccacgttt tgggaatcca actccaagag tggcagagac
    16921 gcctgctggt atgctcaatg caattggctt gcaaaatcct ggtttagagg ttgttttggc
    16981 tgaaaagcta ccttggctgg aaagagaata tccaaatctt cctattattg ccaatgtagc
    17041 tggtttttca aaacaagagt atgcagctgt ttctcatggg atttccaagg caactaatgt
    17101 aaaagctatc gagctcaata tttcttgtcc caatgttgac cactgtaatc atggactttt
    17161 gattggtcaa gatccagatt tggcttatga tgtggtgaaa gcagctgtgg aagcctcaga
    17221 agtgccagtt tatgtcaaat taaccccgag tgtgaccgat atcgttactg tcgcaaaagc
    17281 tgcagaagat gcgggagcaa gtggcttgac catgatcaat actctggttg gaatgcgctt
    17341 tgacctcaaa accagaaaac caatcttggc caatggaaca ggtggaatgt caggtccagc
    17401 agtctttcca gtagccctca aactcatccg ccaagtagcc caaacaacag acctgcctat
    17461 cattggaatg gggggagtgg attcggctga agctgcccta gaaatgtatc tggctggggc
    17521 atctgctatc ggagttggaa cagctaactt taccaatcct tatgcctgcc ctgacatcat
    17581 cgaaaattta ccaaaagtca tggataaata cggtattagc agtctggaag aactccgtca
    17641 ggaagtaaaa gagtctctga ggtaaactgc aatcaatctg ttcttgattt tttattagtt
    17701 tgtaatatga atttaggaga attttggtac aataaaataa ataagaacag aggaagaagg
    17761 ttaatgaaga aagtaagatt tattttttta gctctgctat ttttcttagc tagtccagag
    17821 ggtgcaatgg ctagtgatgg tacttggcaa ggaaaacagt atctgaaaga agatggcagt
    17881 caagcagcga atgagtgggt ttttgatact cattatcaat cttggttcta tataaaagca
    17941 gatgctaact atgctgataa tgaatggcta aagcaaggtg acgactattt ttacctcaaa
    18001 tctggtggct atatggccaa atcagaatgg gtagaagaca agggagtctt ttattatctt
    18061 gaccaagatg gaaagatgaa aagaaatgct tgggtaggaa cttcctatgt tggtgcaaca
    18121 ggtgccaaag taatagaaga ctgggtctat gattctcaat acgatgcttg gttttatatc
    18181 aaagcagatg gacagcacgc agagaaagaa tggctccaaa ttaaagggaa ggactattat
    18241 ttcaaatccg gtggttatct actgacaagt cagtggatta atcaagctta tgtgaatgct
    18301 agtggtgcca aagtgcagca aggttggctt tttgacaaac aataccaatc ttggttttac
    18361 atcaaagaaa atggaaacta tgctgataaa gaatggattt tcgagaatgg tcactattat
    18421 tatctaaaat ccggtggcta catggcagcc aatgaatgga tttgggataa ggaatcttgg
    18481 ttttatctca aatttgatgg gaaaatagct gaaaaagaat gggtctacga ttctcatagt
    18541 caagcctggt actacttcaa atccggtggt tacatgacag ccaatgaatg gatttgggat
    18601 aaggaatctt ggttttacct caaatctgat gggaaaatag ctgaaaaaga atgggtctac
    18661 gattctcata gtcaagcttg gtactacttc aaatccggtg gttacatgac agccaatgaa
    18721 tggatttggg ataaggaatc ttggttttac ctcaagtctg atggcaaaat ggctgaaaaa
    18781 gaatgggtct acgattctca tagtcaagcc tggtactact tcaaatctgg tggctacatg
    18841 gcgaaaaatg agacagtaga tggttatcag cttggaagcg atggtaaatg gcttggagga
    18901 aaagctacaa atgaaaatgc tgcttactat caagtagtgc ctgtcacagc caatgtttat
    18961 gattcagatg gtgaaaagct ttcctatata tcgcaaggta gtgtcgtatg gctagataag
    19021 gatagaaaaa gtgatgacaa gcgcttggct attactattt ctggtttgtc aggctatatg
    19081 aaaacagaag atttacaagc gctagatgct agtaaggact ttatccctta ttatgagagt
    19141 gatggccacc gtttttatca ctatgtggct cagaatgcta gtatcccagt agcttctcat
    19201 ctttctgata tggaagtagg caagaaatat tattcggcag atggcctgca ttttgatggt
    19261 tttaagcttg agaatccctt ccttttcaaa gatttaacag aggctacaaa ctacagtgct
    19321 gaagaattgg ataaggtatt tagtttgcta aacattaaca atagcctttt ggagaacaag
    19381 ggcgctactt ttaaggaagc cgaagaacat taccatatca atgctcttta tctccttgcc
    19441 catagtgccc tagaaagtaa ctggggaaga agtaaaattg ccaaagataa gaataatttc
    19501 tttggcatta cagcctatga tacgacccct tacctttctg ctaagacatt tgatgatgtg
    19561 gataagggaa ttttaggtgc aaccaagtgg attaaggaaa attatatcga taggggaaga
    19621 actttccttg gaaacaaggc ttctggtatg aatgtggaat atgcttcaga cccttattgg
    19681 ggcgaaaaaa ttgctagtgt gatgatgaaa atcaatgaga agctaggtgg caaagattag
    19741 tactataagt gaatatgatt tgagtgaata gtaagttaaa aatcctgatt tcaagtaaaa
    19801 tcaggatttt ttcatggatg caattttttt ggagtctggt gtgacgcgga gggtcttttg
    19861 tcctgtgtaa gtgacaaagc cgggttttcc accagttggt ttattgagtt ttttgacttc
    19921 aatcatatct acctgcacca gattcgacag gcgcccttga gagaagtagg cagctaactc
    19981 tgctgcgtct gtcttgactg catcagatgg gtcaagattt cctgagatga caacatggct
    20041 tccaggaatg tccttagcat ggaaccaaag ttcctccttg cgggccattt taaaggtcaa
    20101 ttcctcattt tgaagattgt ttcgtccgac atagatgatg gttttgccat cgcttgctag
    20161 atattgttct agttttttgc gtttctggat tttctcccgt tgtcttctgc ggataaaacc
    20221 tgtttgaatc aattcttcac ggatttcagc gatttcttcc agtccagctt ggttgaggac
    20281 ggtttctaca ctttccagat agagaatagt ggctttggtt tcttcaatca aatcagtcaa
    20341 gtatttgaca gcttctttga gtttctgata ccgtttaaaa tagcgttggg cattctggtt
    20401 gggagtcaga gccttatcaa gcgcaatcat gataggttgg ttggtatagt agttgtctag
    20461 gataacctgg tcttggtcgt taggcacttg gtggaggaag gttgtcagca attctccttt
    20521 ttgacgaaat tcttcagcgt tgtctgtcgc cagtaactct ttttcctgtt ttttgagttt
    20581 gtgtcggttt ttctgaagtt cattttcaac acgacgaatc agttcactgg cctgctgttt
    20641 gacgcggtcg cgctcagcct tatccttata gtaggtgtcc aacaaatcag aaagatttgc
    20701 aaaaggctct cccacctgat ttgcaaaagg aactggactg aaggaagtct cagtcaagca
    20761 tggcttggtt tcttgattga aaaaatttcg gaaagcggaa agtttttcac taaccagtat
    20821 cctttccaat tcatttgccg tatcgcgtcc cagaccttga aagaggcttt gaagattttt
    20881 tgctgttagt tcttgggttt gtaggatttc aaagagcttt tcatccttga tagtaaaagg
    20941 attgagagat tttgtacttg gcggagcgat ataggtcgat cctggaagta aggtgcggta
    21001 gctattttgt gaaaaaccga cgtgtttgat aacttcgagg attttatgac tgcttttatc
    21061 gaccagtaga atattactgt gttttcccat aatttcaata atcaaggtag cctggatatg
    21121 gtctccaatc tcgtttttat tggaaactgt aatttccaca atacggtcat tttccacttg
    21181 ctcaatcgac tcaatcaggg ccccctgcaa atactttctc aaaaccatga taaaggtaga
    21241 aggttgagct ggattttcaa aagtcgtttg ggtcagctga atgcgtccaa aaactggatg
    21301 ggcagaaagg agcaggcgat ggctttggcg attgctgcgg atttgcaaga ccaactcttg
    21361 ttcaaaaggc tgattgattt tctggatgcg accattcact aattcgcttc gcaattcctc
    21421 aactatgtgg tgtaaaaaaa atccgtcaaa tgacatcgtt ctctccttgt gattgtattc
    21481 catagtatta tatcaaaaag gtagaataaa atcatggaaa tgtggtataa taaagccaag
    21541 taaagagaaa cgagaagcac atgtatattg aaatggtaga tgaaactggt caagtttcaa
    21601 aagaaatgtt gcaacaaacc caagaaattt tggaatttgc agccaaaaaa ttaggaaaag
    21661 aagacaagga gatggcagtc acttttgtga ccaatgagcg tagtcatgaa cttaatctgg
    21721 agtaccgtga caccgaccgt ccgacagatg tcatcagcct tgagtataaa ccagaattgg
    21781 aaattgcctt tgacgaagag gatttgcttg aaaatccaga attggcagag atgatgtctg
    21841 agtttgatgc ctatattggg gaattgttca tctctatcga taaggctcat gagcaggccg
    21901 aagaatatgg tcacagcttt gagcgtgaga tgggcttctt ggcagtacac ggctttttac
    21961 atattaacgg ctatgatcac tatactccgg aagaagaagc ggagatgttc ggtttacaag
    22021 aagaaatttt gacagcctat ggactcacaa gacaataaac gaaaatggaa aaatcgtgac
    22081 ttgatatcca gtttagaatt tgccatcaca gggattttta ctgctatcaa ggaagaacga
    22141 aatatgcgaa aacatgcagt gacggctcta gtggtcatcc ttgcaggttt tgtttttcag
    22201 gtgtcacgaa tcgaatggct ctttctccta ttgagtattt tcttggtagt agcctttgag
    22261 attatcaact ctgctattga aaatgtggtg gatttggcca gtcactatca cttttccatg
    22321 ctggctaaaa atgccaagga tatggcggcc ggcgcggtat tagtggtttc tcttttcgca
    22381 gccttaacag gcgcattgat ttttctccca cgaatctggg atttattatt ttaaacagta
    22441 agaggaaatt atgactttta aatcaggctt tgtagccatt ttaggacgtc ccaatgttgg
    22501 gaagtcaacc tttttaaatc acgttatggg gcaaaagatt gccatcatga gtgacaaggc
    22561 gcagacaacg cgcaataaaa tcatgggaat ttacacgact gataaggagc aaattgtctt
    22621 tatcgacaca ccagggattc acaaacctaa aacagctctc ggagatttca tggttgagtc
    22681 tgcctacagt acccttcgcg aagtggacac cgttcttttc atggtgcctg ctgatgaagc
    22741 gcgtggtaag ggggacgata tgattatcga gcgtctcaag gctgccaagg ttcctgtgat
    22801 tttggtggtg aataaaatcg ataaggtcca tccagaccag ctcttgtctc agattgatga
    22861 cttccgtaat caaatggact ttaaggaaat tgttccaatc tcagcccttc agggaaataa
    22921 cgtgtctcgt ctagtggata ttttgagtga aaatctggat gaaggtttcc aatatttccc
    22981 gtctgatcaa atcacagacc atccagaacg tttcttggtt tcagaaatgg ttcgcgagaa
    23041 agtcttgcat ctaactcgtg aagagattcc gcattctgta gcagtagttg ttgactctat
    23101 gaaacgagac gaagagacag acaaggttca catccgtgca accatcatgg tcgagcgcga
    23161 tagccaaaaa gggattatca tcggtaaagg tggcgctatg cttaagaaaa tcggtagcat
    23221 ggcccgtcgt gatatcgaac tcatgctagg agacaaggtc ttcctagaaa cctgggtcaa
    23281 ggtcaagaaa aactggcgcg ataaaaagct agatttggct gactttggct ataatgaaag
    23341 agaatactaa gtagaggtag gctcatgcct gcttcttgtt tttacagaag gaggacttat
    23401 gcctgaatta cctgaggttg aaaccgtttg tcgtggctta gaaaaattga ttataggaaa
    23461 gaagatttcg agtatagaaa ttcgctaccc caagatgatt aagacggatt tggaagagtt
    23521 tcaaagggaa ttgcctagtc agattatcga gtcaatggga cgtcgtggaa aatatttgct
    23581 tttttatctg acagacaagg tcttgatttc ccatttgcgg atggagggca agtattttta
    23641 ctatccagac caaggacctg aacgcaagca tgcccatgtt ttctttcatt ttgaagatgg
    23701 tggcacgctt gtttatgagg atgttcgcaa gtttggaacc atggaactct tggtgcctga
    23761 ccttttagac gcctacttta tttctaaaaa attaggtcct gaaccaagcg aacaagactt
    23821 tgatttacag gtctttcaag ctgcccttgc caagtccaaa aagcctatca aatcccatct
    23881 cctagaccag accttggtag ctggacttgg caatatctat gtggatgagg ttctctggcg
    23941 agctcaggtt catccagcta gaccttccca gactttgaca gcagaagaag cgactgccat
    24001 tcatgaccag accattgctg ttttgggcca ggctgttgaa aaaggtggct ccaccattcg
    24061 gacttatacc aatgcctttg gggaagatgg aagcatgcag gactttcatc aggtctatga
    24121 taagactggt caagaatgtg tacgctgtgg taccatcatt gagaaaattc aactaggcgg
    24181 acgaggcacc cacttttgtc caaactgtca aaggagggac tgatgagaaa aatcatcgga
    24241 atcactgggg gaattgcctc tggtaagtca actgtgacaa attttctaag acagcaaggc
    24301 tttcaagtag tggatgccga cgcagtcgtc caccaactac agaaatctgg tggtcgtctg
    24361 tttgaggctc tagtacagca ctttgggcaa gaaatcattc ttgaaaacgg agaactcaat
    24421 cgccctctcc tagctagtct catcttttca aatcctgaag agcaaaaatg gtctaagcaa
    24481 attcaagggg agattatccg tgaggaactg gctactttga gagaacagtt ggctcagaca
    24541 gaagagattt tcttcatgga tattccccta ctttttgagc aggactacag cgattggttt
    24601 gctgagactt ggttggtcta tgtggaccga gatgcccaag tagaacgctt aatgaaaagg
    24661 gaccagttgt ccaaagatga agctgagtct cgtctggcag cccagtggcc tttagaaaaa
    24721 aagaaagatt tggccagcca ggttcttgat aataatggca atcagaacca gcttcttaat
    24781 caagtgcata tccttcttga gggaggtagg caagatgaca gagattaact ggaaggataa
    24841 tctgcgtatt gcctggtttg gtaattttct gacaggagcc agtatttctt tggttgtacc
    24901 ttttatgccc atcttcgtgg aaaatctagg tgtagggagt cagcaagtcg ctttttatgc
    24961 aggcttagca atttctgtct ctgctatttc cgcggcgctc ttttctccta tttggggtat
    25021 tcttgctgac aaatacggcc gaaaacccat gatgattcgg gcaggtcttg ctatgactat
    25081 cactatggga ggcttggcct ttgtcccaaa tatctattgg ttaatctttc ttcgtttact
    25141 aaacggtgta tttgcaggtt ttgttcctaa tgcaacggca ctgatagcca gtcaggttcc
    25201 aaaggagaaa tcaggctctg ccttaggtac tttgtctaca ggcgtagttg caggtactct
    25261 aactggtccc tttattggtg gctttatcgc agaattattt ggcattcgta cagttttctt
    25321 actggttggt agttttctat ttttagctgc tattttgact atttgcttta tcaaggaaga
    25381 ttttcaacca gtagccaagg aaaaggctat tccaacaaag gaattattta cctcggttaa
    25441 atatccctat cttttgctca atctcttttt aaccagtttt gtcatacaat tttcagctca
    25501 atcgatcggc cctattttgg ctctttatgt acgcgactta gggcagacag agaatcttct
    25561 ttttgtctct ggtttgattg tgtccagtat gggcttttcc agcatgatga gtgcaggagt
    25621 catgggcaag ctaggtgaca aggtgggcaa tcatcgtctc ttggttgtcg cccagtttta
    25681 tttagtcatc atctatctcc tctgtgccaa tgcctctagc ccgcttcaac taggacttta
    25741 tcgattcctc tttggattgg gaaccggtgc cttgattccc ggggttaatg ccctactcag
    25801 caaaatgact cccaaagccg gcatttcgag ggtctttgcc ttcaatcagg tattctttta
    25861 tctgggaggt gttgttggtc ccatggcagg ttctgcagta gcaggtcaat ttggctacca
    25921 tgctgtcttt tatgcgacga gcctttgtgt tgcctttagt tgtctcttta acctgattca
    25981 atttcgaaca ttattaaaag taaaggaaat ctagtgcgag taaaaattaa tctcaaatgc
    26041 tcctcttgtg acagtatcaa ttacctaacc agtaaaaatt caaaaaccca tccagacaag
    26101 attgaggttt taaagtattg tcccaaggaa agaaaagtaa ccctacatct tgaatctaag
    26161 tagattttat ggtaaaataa tagggatttt aaggagtttg atatgtataa cctattatta
    26221 accattttat tagtattatc tgttgtgatt gtgattgcaa ttttcatgca accaaccaaa
    26281 aaccaatcca gcaatgtatt tgatgccagt tcaggtgatt tgtttgaacg cagtaaagct
    26341 cgcggttttg aagctgtaat gcagcgtttg acagggattt tagtcttttt ctggctagcc
    26401 attgccttag cattgacggt attatcaagt agataagaaa ataatgggca ggactaggtc
    26461 tttgcctctt tttattttta aaggatgttt gagaaggttt tacagtaaaa gaaaattaaa
    26521 aaatctagaa agaaaatatg aaagatagaa taaaagaata tttacaagac aagggaaagg
    26581 tgactgttaa tgatttggct caggctttgg gaaaagacag ttccaaggat tttcgtgagt
    26641 tgattaaaac cttgtcctta atggaaagaa agcaccagat tcgctttgaa gaagatggca
    26701 gtctgacctt ggaagccaag aaaaaacatg agattaccct caaggggatt tttcatgccc
    26761 ataaaaatgg ttttggtttt gtcagcctag aaggggaaga ggacgacctt tttgtaggga
    26821 aaaatgatgt caactatgct attgatggtg ataccgtcga ggtagtgatt aagaaagtcg
    26881 ctgaccgcaa taagggaaca gcagcagaag ccaaaattat tgatatccta gaacacagtt
    26941 tgacaacagt tgtcgggcaa atcgttctgg atcaggaaaa gcctaagtat gctggctata
    27001 ttcgttcaaa aaatcagaaa atcagtcaac cgatttatgt taagaaacca gccctaaaat
    27061 tagaaggaac agaagttctc aaagtcttta tcgataaata cccaagcaag aaacatgatt
    27121 tctttgtcgc tagtgtactc gatgtagtgg gacactcaac ggatgtcgga attgatgttc
    27181 ttgaggtctt ggaatcaatg gacattgtat ccgagtttcc agaagctgtt gttaaggaag
    27241 cagaaagtgt gcctgatgct ccgtctcaaa aggatatgga aggtcgtctg gatctaagag
    27301 atgaaattac ctttaccatt gacggtgcgg atgccaagga cttggacgat gcagtgcata
    27361 tcaaggctct gaaaaatggc aatctggagc ttggggttca cattgcagat gtttcttatt
    27421 atgtgaccga ggggtctgcc cttgacaagg aagcccttaa ccgtgcgact tctgtttacg
    27481 tgacagaccg agtggtgcca atgcttccag aacgactatc aaatggcatc tgctctctca
    27541 atccccaagt tgaccgcctg acccagtctg ctattatgga gattgataaa catggtcgtg
    27601 tggtcaacta taccattata caaacagtta tcaagaccag ttttcgtatg acctatagcg
    27661 atgtcaatga tatcctagct gtcgatgaag aaaagagaaa agaatatcat aaaattgtat
    27721 caagtatcga actcatggcc aagcttcatg aaactttaga aaacatgcgt gtgaaacgtg
    27781 gagctctcaa ttttgatacc aatgaagcga agattttagt ggataaacaa ggtaagcctg
    27841 ttgatatcgt tcttcggcag cgtggcattg ccgagcggat gattgagtct tttatgttga
    27901 tggctaatga aacagttgcc gaacatttca gcaagttgga tttgcctttt atctatcgaa
    27961 ttcacgagga gcctaaggct gaaaaggttc agaagtttat tgattatgct tcgagttttg
    28021 gcttgcgtat ttatgggact gccagtgaga ttagtcagga ggcacttcaa gacatcatgc
    28081 gtgctgttga gggagaacct tatgcagatg tattgtccat gatgcttctt cgctctatgc
    28141 agcaggctcg ttattcggag cacaatcacg gccactatgg actagctgct gactattata
    28201 ctcactttac cagtccaatt cgtcgttatc cagaccttct tgttcaccgt atgattcggg
    28261 attacggccg ttctaaggaa atagcagagc attttgaaca agtgattcca gagattgcga
    28321 cccagtcttc caaccgtgaa cgtcgtgcca tagaagctga gcgtgaagtc gaagccatga
    28381 aaaaggctga gtatatggaa gaatacgtgg gtgaagagta tgatgcagtt gtatcaagta
    28441 ttgtcaaatt cggtctcttt gtcgaattgc caaacacagt tgaaggcttg attcacatca
    28501 ctaatctacc tgaattttat catttcaatg agcgtgattt gactcttcgt ggagaaaaat
    28561 caggtatcac tttccgagtg ggtcagcaga tccgtatccg tgttgaaaga gcggataaaa
    28621 tgactggaga gattgatttt tcattcgtac ctagtgagtt tgatgtgatt gaaaaaggct
    28681 tgaaacagtc tagtcatagt ggcagagggc gtggttcaaa tcgtcgttcg gataagaagg
    28741 aagacaagag aaaatcagga cgctcaaatg ataagcgtaa gcattcacaa aaagacaaga
    28801 agaaaaaagg aaagaaacct ttttacaagg aagtagctaa gaaaggagcc aagcatggca
    28861 aagggcgagg gaaaggtcgt cgcacaaaat aaaaaggcac gccacgacta tacaatcgta
    28921 gatacgctag aggcagggat ggtcctgact ggaactgaaa tcaagagtgt acgagctgct
    28981 cgaattaatc tcaaggatgg ctttgctcaa gtgaaaaatg gagaagtttg gctgagcaat
    29041 gttcatatcg cgccttacga agagggcaat atctggaacc aggaaccaga acgtcgtcgt
    29101 aaactcctgc tccataaaaa gcaaattcaa aaattggaac aagagaccaa agggacagga
    29161 atgaccttag ttccccttaa ggtctatata aaagatggct acgctaagct tcttttagga
    29221 cttgccaaag ggaagcatga ctatgacaaa cgggagtcta tcaaacgtcg tgagcaaaat
    29281 cgagatatcg cgcgtgtgat gaaagctgtt aatcagcgat aaaaagagga attgaaaatg
    29341 gaaaaattag ttgcctataa acgcatgcct ttgtggaata aacaaacaat gcctgaagct
    29401 gttcagcaaa agcacaatac aaaagttggg acttggggga aaattactgt cttgaaggga
    29461 gctctcaagt ttattgaatt gacagaagaa ggggaagttc tagctgaaca cctctttgaa
    29521 gcaggggcag acaatccaat ggcccaacct caagcctggc accgagtgga agctgccaca
    29581 gatgatgtgg aatggtactt ggaattttat tgtaaacctg aggattattt tgctaaaaaa
    29641 tacaatacca atcctgttca ttcagaggtc ctagaggcca tgcagacagt gaaacaaggg
    29701 aaagctttgg atttgggttg tggtcaggga cgtaattctc tttttctagc ccagcaagat
    29761 tttgatgtga cggctgtaga tcaaaatgga ctagctcttg aaatcttgca aagcattgtg
    29821 gagcaggaag atttggacat gcctgttggc ctttacgata tcaattcagc tagcattgaa
    29881 caagaatatg attttatcgt ttcaacagtt gttctcatgt ttctacaagc ggaccgcatt
    29941 ccagctatta ttcaaaatat gcaggagaaa accagtgttg gtggttacaa ccttatcgtt
    30001 tgtgccatgg acacggagga ttatccttgc tcggttaact tcccattcac ctttaaagaa
    30061 ggagaactgg cagactatta caaggattgg gaattggtta agtacaatga aaatccaggc
    30121 catttgcatc gtcgcgatga gaatggcaat cgtattcaac tacgctttgc gaccttacta
    30181 gctaagaaaa tcaagtaaac acacatgaag attaggaatt ttcctgatct tttttctttt
    30241 ttacgaatga tatagaaaag gagggaattc atgtttgttg cgagagatgc taggggagaa
    30301 ttggtaaatg tgttagagga taaacttgag aagcaagcat acacctgccc agcttgtgga
    30361 ggccagatcc atttgcgtca aggaccaagt gtacggacgc attttgccca taaatcctta
    30421 aaagactgtg attttttctt tgaaaatgaa agtccagaac acatagccaa taaggaatcc
    30481 ctctatcact ggttgaaaaa agagacaaag gttcaattag agtacccgct ttcagaactt
    30541 aaacagattg cggatgtatt tgtaaatggc aatctagctc tagaagttca gtgtagtccc
    30601 ttgcctcaga aagtccttaa agagcgaagt gagggctatc gtagtcaggg ttaccaagta
    30661 ctgtggttgc tgggtaaaaa actgtggctc aaggagcgtt tgacttgtct acagcaaggt
    30721 tttctttatt tcagtcaaaa catgggcttt tatgtttggg aattagacaa ggaaaaacaa
    30781 gttttaagac tcaaatacct gatttaccag gatctccgcg gtaaactcca ttatcaaatc
    30841 aaggaatttt cctatggtca aggtagttta ttggaaatat tgcgtcttcc ctataagaga
    30901 caaaaaatat ctcattttac agtttctgag gacaaggaca tctgtcgcta tatccggcaa
    30961 caactttatt atcaaaatct cttttggatg aaagaacaag cagaagccta tcaaaaggga
    31021 gaaaatatcc tgacttatgg actgaaagaa tggtatccac aaattcgacc aatagtgggc
    31081 aaatttttcc agattaaaca agacttgact agctattatc agcactttta tacctattac
    31141 caaaaaaatc ctcaaaatga ttggcaaaag ctttatccac cagcctttta tcagcaatat
    31201 ttcttgaaaa atatggtaga atagaaagga tggaggaatc taatggtatt acaaagaaat
    31261 gaaataaatg aaaaagatac atgggatcta tcaacgatct acccaactga ccaggcttgg
    31321 gaagaagcct taaaagattt aacagaacaa ttggagacag tagcccagta tgaaggccat
    31381 ctcttggata gtgcggataa cctactagaa atcactgaat tttctcttga aatggaacgc
    31441 cagatggaga agctttacgt ttatgctcat atgaagaatg accaggatac acgtgaagct
    31501 aagtatcaag agtactatgc caaggccatg acactctaca gccagttaga ccaagccttt
    31561 tcattctatg agcctgaatt tatggagatt agcgaaaagc agtatgctga ctttttagaa
    31621 gctcaaccaa agctgcaggt ttatcaacac tattttgaca agctcttgca aggcaaggat
    31681 cacgttctct cacaacgtga agaagaatta ttggctggag ctggagaaat ctttggttca
    31741 gcaagtgaaa ccttcgctat cttggacaat gcggatattg tgttccctta tgtcctagac
    31801 gatgatggta aagaagttca gctatctcat gggacttaca cacgtttgat ggagtctaaa
    31861 aaacgtgagg ttcgccgtgg tgcctatcaa gctctttatg cgacttacga acaattccaa
    31921 cacacctatg ccaaaacctt gcaaaccaat gttaaggtgc aaaattaccg tgctaaagtt
    31981 cgtaactaca agagtgctcg tcatgcagcc ctcgcagcga attttgttcc agaaagtgtt
    32041 tatgacaatt tggtagcagc agttcgcaag catttgccac tcttacatcg ctatcttgag
    32101 cttcgttcaa aaatcttggg gatttcagat ctcaagatgt acgatgttta cacaccgctt
    32161 tcatctgttg aatacagttt tacctaccaa gaagccttga aaaaagcaga agatgctttg
    32221 gcagtcttgg gtgaggatta cttgagccgt gttaaacgtg ccttcagcga gcgttggatt
    32281 gatgtttacg aaaatcaagg caagcgttca ggtgcctact ctggtggttc ttacgatacc
    32341 aatgccttta tgcttctcaa ctggcaggac aatctggaca atctctttac tcttgttcat
    32401 gaaacaggtc acagtatgca ttcaagctat actcgtgaaa ctcagcctta tgtttacgga
    32461 gattactcta tctttttggc tgagattgcc tcaactacca atgaaaatat cttgacggag
    32521 aaattattgg aagaagtgga agacgacgca acacgttttg ctattctcaa taacttccta
    32581 gatggtttcc gtggaacagt tttccgccaa actcaatttg ctgagtttga acacgccatt
    32641 caccaagcag atcaaaatgg ggaggtcttg acaagcgatt tcctaaataa actctacgca
    32701 tacttgaacc aagagtatta tggtttgagt aaggaagaca atcctgaaat ccaatacgag
    32761 tgggctcgca ttccacactt ctactataac tactatgtat atcaatattc aactggcttt
    32821 gcggccgcct cagccttggc tgaaaaaatt gtccatggta gtcaagaaga ccgtgaccgc
    32881 tatatcgact acctcaaggc aggtaagtcg gactatccac ttaatgtcat gagaaaagct
    32941 ggtgttgata tggagaagga agactacctc aacgatgcct ttgcagtctt tgaacgccgt
    33001 ttaaatgagt ttgaagccct tgttgaaaaa ttaggattgg cataaaatgg ttgaatcgta
    33061 tagtaagaat gctaaccata acatgcgtcg tcctgtcgtc aaagaagaaa ttgtagactt
    33121 gatgcgtcag cgtcaaaagc aagtcacagg tttcttgaaa gaattggaag actttgcccg
    33181 caaggaaaat attcctatta ttccccatga aacggttgct tatttccgtt ttcttatgga
    33241 aaccatgcag cctaaaaata ttctggaaat tgggacggct atcggttttt cagctctctt
    33301 gatggctgaa catgcgccaa atgctaagat tacaactatt gatcgtaatc cagaaatgat
    33361 tggttttgcc aaggaaaatt ttgcccagtt tgacagtcgc aagcaaatca ctctcctaga
    33421 gggagatgcg gtggatgtct tatctacact gacagagtct tatgatttcg tctttatgga
    33481 ttctgccaag tctaaataca tcgtctttct gccagaaatc ctcaaacatt tggaagttgg
    33541 tggtgtggtt gtcttggatg atatttttca aggtggtgat gttgccaagg atattatgga
    33601 agtccgtcgt ggtcagcgaa ccatttatcg aggccttcaa aaattatttg atgcaacctt
    33661 agacaatcca gaactcaccg caacattagt gcctttagga gatggtattc tcatgcttcg
    33721 taaaaatgta gcagatgttc aactgtctga aagcgaatga ttttcagaaa aatttaagaa
    33781 aaaatagtaa aatagataga gtaacactta tctcaaagga gtagacatga agaaaaaatt
    33841 attggcaggt gccatcacac tattatcagt agcaacttta gcagcttgtt cgaaagggtc
    33901 agaaggggca gaccttatca gtatgaaagg ggatgtcatc acagaacatc aattttatga
    33961 gcaagtgaaa aacaaccctt cagcccaaca agtcttgtta aatatgacca tccaaaaagt
    34021 ttttgaaaaa caatatggct cagagcttga tgataaagag gttgatgata ctattgccga
    34081 agaaaaaaaa caatatggcg aaaactacca acgtgtcttg tcacaagcag gtatgactct
    34141 tgaaacacgt aaagctcaaa ttcgtacaag taaattagtt gagttggcag ttaagaaggt
    34201 agcagaagct gaattgacag atgaagccta taagaaagcc tttgatgagt acactccaga
    34261 tgtaacggct caaatcatcc gtcttaataa tgaagataag gccaaagaag ttctcgaaaa
    34321 agccaaggca gaaggtgctg attttgctca attagccaaa gataattcaa ctgatgaaaa
    34381 aacaaaagaa aatggtggag aaattacctt tgattctgct tcaacagaag tacctgagca
    34441 agtcaaaaaa gccgctttcg ctttagatgt ggatggtgtt tctgatgtga ttacagcaac
    34501 tggcacacaa gcctacagta gccaatatta cattgtaaaa ctcactaaga aaacagaaaa
    34561 atcatctaat attgatgact acaaagaaaa attaaaaact gttatcttga ctcaaaaaca
    34621 aaatgattca acatttgttc aaagcattat cggaaaagaa ttgcaagcag ctaatattaa
    34681 ggttaaggac caagccttcc aaaatatctt tacccaatat atcggtggtg gagattcaag
    34741 ctcaagcagt agtacatcaa acgaatagtc caaatcaatg agtcagggaa aaaactcgac
    34801 ttcaggaaaa aatgaagcaa acattcccac aataaaacgc atagtacaag gtttgtactg
    34861 ccccccaaaa aagttagaca attaatttat ccgaaggatt tagttctgta ttgcacagag
    34921 ctaagtcctt ttagttttat cttaattctc ttattgttgt aataatcaat atagtctata
    34981 atggcttgtt ccaattgatt aagtgattta aatgtttgct catagccata aaacatttcg
    35041 gattttaaaa tgccaaagaa agattccatc ctaccgttgt cttggctgtt tcctttgcgt
    35101 gacatagatg cttgaattcc cttactctct aggaagcgat gataagaatc gtgttggtat
    35161 tgccagcctt ggtcactatg gagaatcgta ttctcgtagt gcttctcttt gaatgcctgt
    35221 tccaacatta acgatcaatc aatttaatca tgtacctaag attagaattg tttatcccaa
    35281 atttatttga aagcttctct aagcttaagc tatatccttg ttttctaagt tcatagatct
    35341 gaactttatc atcataagtt aatttcataa taaaaacacc ccaaaagtta gattttttct
    35401 gtctaacttt tggggtgtag ttcatgtaca cctgatatga tgcgttttat aattttaaag
    35461 actttttgac cagcctcatt tttttaactt gatactcagt gaaaagcaaa gattaaacta
    35521 ggaagctagc tgtaggctgc tcaaagaaca gctttgaggt tgcagataaa acttgtgagg
    35581 taaccaacat atataatgtg aagctgacgt ggtttgaata gattttagaa gggtatgagt
    35641 ctggaagttt taatggataa tgcaagattc catagaatgg gtaagctaga gttcttatgt
    35701 gaagagtttg ggcataaact tttacctttt cctccctact catcttagta tagaaaagtg
    35761 aatctaaaat agtacataac tgcttctaaa acattcttat aaattgattt aaattctcaa
    35821 atcatattat tcagttctta tttcattttg ctctacaatc ctgttgagaa gacacgtgtt
    35881 catatcaaaa aggtattggc aagttgcaat acctttttac aaggttcttt tgtcttattt
    35941 ttgtttcaac tgactatatc tcctatggtt ctagttcaga aggctaggct ataattatga
    36001 ttgataagaa gtatcattcc aagtattgag agtgaatgtt tcaaaatcat gggtttctat
    36061 aatggtcagg ctggcatttg ctagaccgcc atctttacga agaagtggtt ctttatagcc
    36121 taggagagta cgaagactgg cagtaagatt ggcgccgtgt ccgacaatta gaatacgctc
    36181 agctggacta tcttttaatg atttgataaa ttggatggtc cgctgagttg tactatagag
    36241 ggattcggct ccgaacattc gagtgtcaaa ttgagcaaga tttgaacgaa aagcctggat
    36301 ttgttgcggg taaatagctt ccagggttgc aattttcaaa ccttctaact tcccaagttg
    36361 ccattcacgg agattaggaa cgatttctaa agaacagggg gtatggagtt gactttggat
    36421 aatctcagca gatttgaccg ctcgaggtaa atcacttgaa taaatctgat caaaaggaat
    36481 ttccttgaga tactggccaa gtcgttttag ggtttcaatg gatccaggaa gaagaggaga
    36541 atcaccgcta gcaccttgaa aacgaccttc ttggttccag agggtacgac cgtggcggac
    36601 aaagtagagt ttcattactt gatgtcctcc aaaatatcta caaagtctgc ctttacaaag
    36661 ctagccaagt cttgtggcgc gacgataatg ctgtgtccga cttcgcctgc agagacaatc
    36721 attcgatcca aatctagagc aattttatcg ataaaaatgg gataattgtg tttctgacga
    36781 attccgacag gattattggc tccatgaatg taaccagttg ttttttctaa gtccttttgt
    36841 ggaatcatgc tcattttttt attgccagaa attttagcta gtttcttttc agacaagtgc
    36901 tgagtgatag ggacaattcc gataatcggt ccggtcttgt ctcccaaaag cgccaaggtt
    36961 ttgaaaatct gatctcgttc ataaccttga ggaagctctc cttctagggc attgatttga
    37021 atcccctgat gagggatagc tgctttagat aggatttgtt ccaccaatgt ttttttgatt
    37081 ttaacttttt ttgccattat ttatatttat cctccaattg actcatccaa ataccaagcc
    37141 agattcccag cgcaaagaag aaggcgatga tgacataacc gacaagtgaa agtcctgtgt
    37201 attggatact ttcagcgttt cctgcatttg gaattaagat caaaagggta cttgatagga
    37261 cgataccgat gatgaaatga tagacgcgtg agtggtagtt gtttaaggca taatccatca
    37321 attttgaaaa aacgatgaga gttgcacctg caccaattcc aatcggaaag aaggttccca
    37381 agagatcaaa agttttaaaa ccagtcaaca taggagcata gagtcccaaa atcaaaagta
    37441 aattcgatgg gctgaggcca ggaaccaaga cgccaagggc caatagtgcg cctgctagga
    37501 cgaagttaag aaagctggcg cttaaggttc caacgacaaa atttaaggca tagagtccta
    37561 atccagaaat gataaaggtt gtccataacc aagctaaatc aatcttgtct cggtcagatt
    37621 ctcgagttga ttctttgagg aggctaggaa ctgtaccgat aatagctccc gcaaagctcc
    37681 ataatacaaa gacctgataa ttttcaagca ggtattcaat cgggtaggaa aataagccga
    37741 ttcccagaag cataccgatg gcaactggaa taaagtacaa aacattttct ttaaagtctt
    37801 taaagggatg ggccagaaag ccaatcattc gttcatagat tcctaagatt gctgctagaa
    37861 cccctccgga aattcccggt aggataaatc caagagcaat tacaatccct ttaataacgc
    37921 gtgctaacca tgagagcata tatttcctcc aactatttct atttcaaaaa atccttacta
    37981 tattgtatca caatcagaca caaaaagaaa aagcaaatga taaacaaatg cttttaaggt
    38041 tttaaaaaaa gttttcgaaa ggtttcttct ttatttttta agggagagat aacgttgata
    38101 tctaaatcgt ggtcaaagcc ggcaattttt cctttagatg tgtattggtg aatatcataa
    38161 tctaaatcag ttttaggact gctttccaaa aatcctgagt ctgagccgta gaacggaatc
    38221 caaacagagg taaacttgcc tgtatcaata ctgtgttctt ccatgaagta gacaccaacg
    38281 tagatgccga tgtttttagc acccagtgat gctagttttg ctcgaaagtt ttcgacacct
    38341 tcgttcatat tagacatggt tttgtcttcc acgtcaagcc aatagtaact agggctgtaa
    38401 ggagaggcag cattgtagaa aacttcggca gccttttcca tttcttggac actttttcca
    38461 gctacataag cgtagacagc aactgggaca ttccgctttt gaagttcagt gatatgactc
    38521 ttataggcct tgtctattcc attgataaat gaagcatcat tttcttttgt cgtttgagca
    38581 ccactgtgaa cacgaacaat agcacctgaa atattttgtg agagggcatc gtagttgatt
    38641 tcctcaggac gctgccagcc agagaggtca ataatcggtt tgtctaagtg tttcaaagcc
    38701 tgtgcttcaa tctgtgctat attggatttt gttttaaacg attggctgtc attaagtggg
    38761 cgattgatga ttaaaatgaa catcataatc ccaaaaaaac taaataaaat aagtggatga
    38821 atttgttttc tcatatctta taattctacc ctaaaaatca aaaaaaatca aaaaaatggg
    38881 ttaaggaaga gactttagag cattttttca ttcaagagtg cggaatgatt tgaaatatgg
    38941 tataataaaa gggaatttct acagaaaagg gaagattatg tcaaattttg ccattatttt
    39001 agcagcgggt aaagggactc gcatgaaatc tgatttgcca aaagttttgc acaaggttgc
    39061 gggtatttct atgttggaac atgttttccg tagtgtggga gctatccaac ctgaaaagac
    39121 agtaacagtt gtaggacaca aggcagaatt ggttgaggag gtcttggctg gacagacaga
    39181 atttgtgact caatctgaac agttgggaac tggtcatgca gttatgatga cagagcctat
    39241 cttagaaggt ttgtcaggac acaccttggt cattgcagga gatactcctt taatcactgg
    39301 tgaaagcttg aaaaacttga ttgatttcca tatcaatcat aaaaatgtgg ccactatctt
    39361 gactgctgaa acggataatc cttttggtta tggacgaatt gttcgtaatg acaatgctga
    39421 ggttcttcgt attgttgagc agaaggatgc tacagatttt gaaaagcaaa tcaaggaaat
    39481 caacactgga acatacgtct ttgacaacga gcgtttgttt gaggctttga aaaatatcaa
    39541 taccaataac gctcaaggcg aatactatat tacagacgtc attggtattt tccgtgaaac
    39601 tggtgaaaaa gttggcgctt atactttgaa agattttgat gaaagtcttg gggtaaatga
    39661 ccgtgtggcg cttgcgacag ctgagtcagt tatgcgtcgt cgcatcaatc ataaacacat
    39721 ggtcaacggt gttagctttg tcaatccaga agcaacttat atcgatattg atgttgagat
    39781 tgcttcggaa gttcaaatcg aagccaatgt tatcttgaaa gggcaaacga aaattggtgc
    39841 tgagactgtt ttgacaaacg gtacttatgt agtggacagc actatcggag caggagcggt
    39901 cattaccaat tctatgattg aggaaagtag tgttgcagac ggtgtgatag tcggtcctta
    39961 tgctcacatt cgtccaaatt caagtctggg tgcccaagtt catattggta actttgttga
    40021 ggtgaaagga tcttcaatcg gtgagaatac caaggctggt catttgactt atatcggaaa
    40081 ctgtgaagtg ggaagcaacg ttaatttcgg tgctggaact attacagtca actatgacgg
    40141 caaaaacaaa tacaagacag tcattggaaa caatgtcttt gttggttcaa attcaaccat
    40201 tattgcacca gtagaacttg gtgacaattc cctcgttggt gctggttcaa ctattactaa
    40261 agacgtgcca gcagatgcta ttgctattgg tcgcggtcgt cagatcaata aagacgaata
    40321 tgcaacacgt cttcctcatc atcctaagaa ccagtaggag cctatcatgg agtttgaaga
    40381 aaaaacgctt agccgaaaag aaatctatca aggaccaata tttaaactgg tccaagatca
    40441 ggttgaatta ccagaaggca agggaactgc ccaacgggat ttgattttcc acaatggggc
    40501 tgtctgtgtt ttagcagtaa cggatgaaca aaaacttatc ttggtcaagc agtaccgcaa
    40561 agctatcgag gctgtctctt acgaaattcc agccggaaaa ttggaagtag gagaaaacac
    40621 agcccctgtg gcagctgccc ttcgtgaatt agaggaagaa acagcctata cagggaaatt
    40681 agaactcttg tacgattttt attcagctat tggcttttgt aatgagaagt taaaactata
    40741 tttagcaagc gatttgacaa aagtggaaaa tccgcgtccg caggatgagg atgaaacctt
    40801 ggaagtcctt gaagtgagct tagaagaagc gaaagaatta atccaatcag gtcatatttg
    40861 tgatgccaag acaattatgg ctgttcagta ttgggagttg cagaaaaaat agaggaggtc
    40921 agtatgggta aatctttatt aacggatgaa atgattgaaa gagctaatag aggcgaaaaa
    40981 atttcaggtc ctcctttgct agatgataat gaggaaacta agattttacc aacctcttct
    41041 tcccgttttg gttatgccaa tcctaaggat catggtttta gccaggaaac cttgaagatt
    41101 caggtcgaac catctattca taaaagccgt cgtattgaaa ataccaagag aaatgtcttc
    41161 aattctaagt tgaataaaat cttatttgcg gtcatctttc tcttgatttt gcttgtttta
    41221 gcaatgaaac ttttgtaata gaaaaggaat tgaaatgaaa ataggaatta ttgctgctat
    41281 gccagaagaa ctggcttatc tggtccagca tttagataat gcccaggagc aagttgtttt
    41341 ggggaatacc tatcatacag gaaccattgc ttctcatgaa gtcgttcttg tagaaagtgg
    41401 aattggtaag gtcatgtctg ctatgagtgt ggcgattttg gctgatcatt tccaggtgga
    41461 tgcccttatt aatacgggtt cagctggggc agtagcagaa ggtatcgctg ttggggatgt
    41521 cgtgattgct gacaaattag cctatcatga cgtggatgtc acagcttttg gctatgctta
    41581 tggacaaatg gcgcaacaac cgctttattt cgaatcagac aaaacctttg ttgctcaaat
    41641 ccaagagagt ttatctcaat tggaccaaaa ctggcatctt ggtttgattg ctacaggaga
    41701 tagttttgtt gcaggaaatg acaagataga agcgattaag tcccatttcc cagaagtttt
    41761 agccgtggag atggaggggg cagctattgc tcaagcagcg catgccctca atctcccagt
    41821 cttagtcatc cgagctatga gtgacaatgc caaccatgaa gcaaacatct tttttgatga
    41881 gtttattatc gaagctggac gtcgctctgc ccaagtcttg ttgacctttt tgaaggcttt
    41941 agattaagcg gaaatttgac agtttttcta gcttatgata agatttaagt aaagaaaagc
    42001 tagaaaacgt ttcagaggat attatgagta ttgaaatgac cgtcagtgag attgcagagg
    42061 tcttaggatt atctcgccaa gcaatcaata accgtgtcaa agaattacca gaagaagaca
    42121 cagataaaaa tgacaaaggg gtaacagttg ttaccagaag tggcttgatt aagctagaag
    42181 aaatctataa aaaaacgatt tttgaagatg agcctgtcag tgaagatgtc aaacaacgtg
    42241 aactgatgga gattctagtg gatgagaaga atgcagaaat tcttcgtctt tatgaacaat
    42301 taaaagccaa ggatcgtcag ttatcagaaa aagacgagca gatgcgtatc aaagaccgtc
    42361 agattgctga gaaagacaaa caattagatc agcaacaaca attgaccctt caagccatga
    42421 aggatcaaga aaatcttaag ctagagctgg accaagcaaa agaagaagtc caatccacta
    42481 agaaaggctt ttttgctcgt ttatttggag gataatcaag gagctgttta ggttaaatgc
    42541 taacctgatg gcttcttttg tttgtgaata gtatagttga ttagaacaga gacagtagag
    42601 gagaggtaca gaatggaacg attagaagat tacattgctt ttgacttaga atttaatcag
    42661 cacgaaggac aaacacactt gattcaagta tcggcagtgc gttttagaga tggtcgggaa
    42721 atcgatgcct atgattccta tgttcatacc agcgtccctc taaaaagctt tatcaatggt
    42781 ttgaccggga ttacagctga gaccttaaaa gatgctcctc cagttgagaa agtcttagaa
    42841 gaattccaag agtttgtggg ttctttgctg atgataggct acaatgctgc taaaagtgat
    42901 ttacctattt tagcagagca tggtttagac tatagccaac agtacaaggt ggatttgtat
    42961 gatgaagctt ttgaacgtcg gagttcagat ttacatggta ttgccaatct caaattgcaa
    43021 actgttgcct catttcttgg atttcaaggt cagtctcata atagtttaga ggatgctcgg
    43081 atgacggcgc gtgtttacga atccttctta gagtcggatc aagctaggga attgttagag
    43141 acagaaagta gcttatcaaa taatcctttt ggtggcttgg acttgtctca attatttgac
    43201 taggagtgcc tatgaaacct gaaaaaccta aaaaattggg tcttaaacag atttacctca
    43261 atcttgataa aatcctcttt ctatttttct tgatttttat gatagtggag tatttgtggg
    43321 taccattcaa ttcatggttg gctagcttct tattagatca gacaggttat ctttttattt
    43381 cctataacaa tgtcttagcc atccttactc attctccatt gattagtcta gcttttttag
    43441 ccttgattgt aattaacttt ctggttgctt attttcaaat aggactcctc tttattggtg
    43501 ctcgtcatct cctctataat gaaaagcgaa ggctaattga gtatatccgc aaggttttcc
    43561 atgaaagttt tgaatttatg aaaaagctaa ctggcgctaa agccttgttt atctttttct
    43621 atatagctat gctgtttcct tttatacgga aaatgctgaa gatttattat cttaataaaa
    43681 tcgtcattcc agagtttatc caagcttatt tagaagataa atattggatg tggtggctga
    43741 gcatcctact tctatctctt atctttctct atgtctctgt cagattgatg tttgcccttc
    43801 cgaagattgt atatgatcag ctgactgttc gagaagcagt gatgtttagc ttggagaaaa
    43861 ccaagaagag agttactttt tatgcttgga atttatttta catcttgctc aaagcacatt
    43921 tattatttta tcttcctttg attcctttat tattggctca aactttggta gatgatatca
    43981 ctcagagaga gtctctgatt cttggtattt tgaattttgt tgtgattaaa aatctctatt
    44041 atatggctct gacttatttt ttggttaaat ttgtttcatt tttgacagga aaggagctgg
    44101 atatgcttcc taggagagaa aaagatcaca tcgtgcgatg gggtgtcatg acttgtgcca
    44161 gtcttttctt tgccttagaa ggttatattt atctggaggc tcccatggtt catctacctc
    44221 aacttatttc tcaccgaggg gtttccaatg caaatgggat tcaaaataca gtagagtcct
    44281 tggaaactac agcacaactc aaaccagact tggtggagac ggacgtgcag gaaacaaaag
    44341 atgggcagtt tgtcatgatg catgatgcta acttgaaaaa tctagcaggt atcaataaaa
    44401 gtcctcaaga cttaaacttg gaggagctta aagggattga tatttttgaa aatggctacc
    44461 agactaaaat ttcaagcttt gaagattatc tcagtcgagc caacgaactt ggtcaaaaat
    44521 tactaattga aattaaaacc agtaaaaaag atagtccaga catgatgaac cgctttttag
    44581 cccgttatgc tgcaaagctc aagatttatg gacatcaaat ccagtcttta gactaccatg
    44641 ttgtcgaaaa agtaagacag tatgatgccg aactgccagt ttatttcatc atgccctaca
    44701 attctgtctt tcctaaaaca agagcgacag gatatactat ggagtactca accttggatg
    44761 aatattttgt aagcaaacta tggacaacgg atcagaaact ttatgtctgg actgtcaatg
    44821 attcagaagc tatcagcaaa tctcttcact taggagtaga tggagtgatt acagatgatt
    44881 tggaaaaagt tcagcgggaa atagaagtag cccaagaaga tccagaatat acggatttgc
    44941 tcttgaaaaa agcattggaa ttctttgaat tttagtaata aaaaagagga acggttgttc
    45001 ctcccatgat aggtaagtat tc
//
LOCUS       DBERXF010000013        44543 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.13, whole genome shotgun sequence.
ACCESSION   DBERXF010000013 DBERXF010000000
VERSION     DBERXF010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 44543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44543
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.13"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            74..506
                     /locus_tag="ACL8JK_000830"
                     /pseudo
     CDS             74..506
                     /locus_tag="ACL8JK_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811998.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            695..994
                     /locus_tag="ACL8JK_000831"
     CDS             695..994
                     /locus_tag="ACL8JK_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGS1785741.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1255..1578
                     /gene="tnpB"
                     /locus_tag="ACL8JK_000832"
     CDS             1255..1578
                     /gene="tnpB"
                     /locus_tag="ACL8JK_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS1785742.1"
                     /translation="MMIQLSDLGQVHLVCGKTDMIQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWILYKRFENGKLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPQI"
     gene            complement(2307..4034)
                     /gene="ezrA"
                     /locus_tag="ACL8JK_000833"
     CDS             complement(2307..4034)
                     /gene="ezrA"
                     /locus_tag="ACL8JK_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGS1785743.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLESGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(4116..6062)
                     /gene="gyrB"
                     /locus_tag="ACL8JK_000834"
     CDS             complement(4116..6062)
                     /gene="gyrB"
                     /locus_tag="ACL8JK_000834"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGS1785744.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(6077..6640)
                     /locus_tag="ACL8JK_000835"
     CDS             complement(6077..6640)
                     /locus_tag="ACL8JK_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS1785745.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQT
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(6725..7279)
                     /locus_tag="ACL8JK_000836"
     CDS             complement(6725..7279)
                     /locus_tag="ACL8JK_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HGS1785746.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(7290..8513)
                     /locus_tag="ACL8JK_000837"
     CDS             complement(7290..8513)
                     /locus_tag="ACL8JK_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGS1785747.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVSLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(8550..11000)
                     /locus_tag="ACL8JK_000838"
     CDS             complement(8550..11000)
                     /locus_tag="ACL8JK_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HGS1785748.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDVHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSCRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATIK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(11200..12129)
                     /locus_tag="ACL8JK_000839"
     CDS             complement(11200..12129)
                     /locus_tag="ACL8JK_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGS1785749.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNWIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            12269..12556
                     /locus_tag="ACL8JK_000840"
     CDS             12269..12556
                     /locus_tag="ACL8JK_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HGS1785750.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(12590..13924)
                     /gene="ciaH"
                     /locus_tag="ACL8JK_000841"
     CDS             complement(12590..13924)
                     /gene="ciaH"
                     /locus_tag="ACL8JK_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HGS1785751.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(13914..14588)
                     /gene="ciaR"
                     /locus_tag="ACL8JK_000842"
     CDS             complement(13914..14588)
                     /gene="ciaR"
                     /locus_tag="ACL8JK_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HGS1785752.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(14697..17243)
                     /locus_tag="ACL8JK_000843"
     CDS             complement(14697..17243)
                     /locus_tag="ACL8JK_000843"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HGS1785753.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(17366..17806)
                     /locus_tag="ACL8JK_000844"
     CDS             complement(17366..17806)
                     /locus_tag="ACL8JK_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGS1785754.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQAHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(17781..18650)
                     /locus_tag="ACL8JK_000845"
     CDS             complement(17781..18650)
                     /locus_tag="ACL8JK_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HGS1785755.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLDTICSFYLGKEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPSVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(18692..19420)
                     /locus_tag="ACL8JK_000846"
     CDS             complement(18692..19420)
                     /locus_tag="ACL8JK_000846"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1785756.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGLAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(19428..19907)
                     /locus_tag="ACL8JK_000847"
     CDS             complement(19428..19907)
                     /locus_tag="ACL8JK_000847"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS1785757.1"
                     /translation="MEIKKHFGVYAVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(19918..20616)
                     /locus_tag="ACL8JK_000848"
     CDS             complement(19918..20616)
                     /locus_tag="ACL8JK_000848"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGS1785758.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(20609..20845)
                     /locus_tag="ACL8JK_000849"
     CDS             complement(20609..20845)
                     /locus_tag="ACL8JK_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGS1785759.1"
                     /translation="MTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTIEQNGLALEMT
                     PYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(20941..21867)
                     /locus_tag="ACL8JK_000850"
     CDS             complement(20941..21867)
                     /locus_tag="ACL8JK_000850"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGS1785760.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEEFVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSVAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(21942..22757)
                     /locus_tag="ACL8JK_000851"
     CDS             complement(21942..22757)
                     /locus_tag="ACL8JK_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785761.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKFGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPDPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFLLFHGFKKIKWSEV"
     gene            complement(22761..23081)
                     /locus_tag="ACL8JK_000852"
     CDS             complement(22761..23081)
                     /locus_tag="ACL8JK_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGS1785762.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(23171..23407)
                     /locus_tag="ACL8JK_000853"
     CDS             complement(23171..23407)
                     /locus_tag="ACL8JK_000853"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785763.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSSKHVFEVVDETDEVS
                     SKHVFEVVDETDEVSNHTYGRATLTWFEEIFEEY"
     gene            complement(23457..25454)
                     /gene="metG"
                     /locus_tag="ACL8JK_000854"
     CDS             complement(23457..25454)
                     /gene="metG"
                     /locus_tag="ACL8JK_000854"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGS1785764.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(25578..26837)
                     /locus_tag="ACL8JK_000855"
     CDS             complement(25578..26837)
                     /locus_tag="ACL8JK_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1785765.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESL
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(26839..27540)
                     /locus_tag="ACL8JK_000856"
     CDS             complement(26839..27540)
                     /locus_tag="ACL8JK_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785766.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(27524..28723)
                     /locus_tag="ACL8JK_000857"
     CDS             complement(27524..28723)
                     /locus_tag="ACL8JK_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HGS1785767.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            29009..30355
                     /gene="gor"
                     /locus_tag="ACL8JK_000858"
     CDS             29009..30355
                     /gene="gor"
                     /locus_tag="ACL8JK_000858"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGS1785768.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGLYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSSCTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            30552..31088
                     /locus_tag="ACL8JK_000859"
     CDS             30552..31088
                     /locus_tag="ACL8JK_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGS1785769.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            31149..31295
                     /locus_tag="ACL8JK_000860"
     CDS             31149..31295
                     /locus_tag="ACL8JK_000860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785770.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKAKLMRFEEI
                     FEEY"
     gene            complement(31292..31507)
                     /locus_tag="ACL8JK_000861"
     CDS             complement(31292..31507)
                     /locus_tag="ACL8JK_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGS1785771.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGASAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            31605..31925
                     /locus_tag="ACL8JK_000862"
     CDS             31605..31925
                     /locus_tag="ACL8JK_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785772.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(31956..32294)
                     /locus_tag="ACL8JK_000863"
     CDS             complement(31956..32294)
                     /locus_tag="ACL8JK_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HGS1785773.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(32306..33025)
                     /gene="trmD"
                     /locus_tag="ACL8JK_000864"
     CDS             complement(32306..33025)
                     /gene="trmD"
                     /locus_tag="ACL8JK_000864"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGS1785774.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(33015..33533)
                     /gene="rimM"
                     /locus_tag="ACL8JK_000865"
     CDS             complement(33015..33533)
                     /gene="rimM"
                     /locus_tag="ACL8JK_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGS1785775.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(33603..34351)
                     /locus_tag="ACL8JK_000866"
                     /pseudo
     CDS             complement(33603..34351)
                     /locus_tag="ACL8JK_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819199.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
     gene            complement(34455..34779)
                     /locus_tag="ACL8JK_000867"
                     /pseudo
     CDS             complement(34455..34779)
                     /locus_tag="ACL8JK_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654120.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG nucleotide pyrophosphohydrolase
                     domain-containing protein"
     gene            complement(34928..35167)
                     /gene="kphA"
                     /locus_tag="ACL8JK_000868"
     CDS             complement(34928..35167)
                     /gene="kphA"
                     /locus_tag="ACL8JK_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein KphA"
                     /protein_id="HGS1785776.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(35187..35459)
                     /gene="rpsP"
                     /locus_tag="ACL8JK_000869"
     CDS             complement(35187..35459)
                     /gene="rpsP"
                     /locus_tag="ACL8JK_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGS1785777.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            35629..35838
                     /locus_tag="ACL8JK_000870"
     CDS             35629..35838
                     /locus_tag="ACL8JK_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785778.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LADDSLAGDIILLWRIQFGTFTTET"
     gene            36317..36538
                     /locus_tag="ACL8JK_000871"
     CDS             36317..36538
                     /locus_tag="ACL8JK_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785779.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            36622..37425
                     /locus_tag="ACL8JK_000872"
     CDS             36622..37425
                     /locus_tag="ACL8JK_000872"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGS1785780.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(37482..39023)
                     /locus_tag="ACL8JK_000873"
     CDS             complement(37482..39023)
                     /locus_tag="ACL8JK_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS1785781.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHELDFYEGWIDQIWD
                     FNNLT"
     gene            complement(39025..39507)
                     /locus_tag="ACL8JK_000874"
     CDS             complement(39025..39507)
                     /locus_tag="ACL8JK_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGS1785782.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(39507..40592)
                     /gene="rlmN"
                     /locus_tag="ACL8JK_000875"
     CDS             complement(39507..40592)
                     /gene="rlmN"
                     /locus_tag="ACL8JK_000875"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGS1785783.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRGVTFEYIMLNEVNDGVEQALE
                     LTELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(40613..41143)
                     /locus_tag="ACL8JK_000876"
     CDS             complement(40613..41143)
                     /locus_tag="ACL8JK_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGS1785784.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(41299..41904)
                     /gene="sodA"
                     /locus_tag="ACL8JK_000877"
     CDS             complement(41299..41904)
                     /gene="sodA"
                     /locus_tag="ACL8JK_000877"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HGS1785785.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(42077..43114)
                     /gene="holA"
                     /locus_tag="ACL8JK_000878"
     CDS             complement(42077..43114)
                     /gene="holA"
                     /locus_tag="ACL8JK_000878"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGS1785786.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(43148..44083)
                     /locus_tag="ACL8JK_000879"
     CDS             complement(43148..44083)
                     /locus_tag="ACL8JK_000879"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGS1785787.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
BASE COUNT        13329 a         9648 c         7975 g        13591 t
ORIGIN      
        1 aagattatac cacattgtgt actatttttg gttcatttca ctataataat aacgatacta
       61 gataatgagg aaaatgcaat ggcaaaccca actttcggag aaaaaaagcg aatacagact
      121 atattgctcg ctatggcgta tatgcagtta tccctaatcc tgaacaaaaa caaattgttc
      181 ttgttcaaga accaaatggt gcttggttcc taccatgtgg agaaattgaa gcaggtgaaa
      241 atcatcagga agccctaaag cgtgagttga ttgaagagct tggtttcaca gcagaaattg
      301 gtacctatta cggacaagct gacgaatatt tctattctcg tcatcgtgat acctactact
      361 acaatcctgc ctacctctat gaagcaactc ctttcaaaga agtacaaaag ccactagaaa
      421 actttaatca tattgcctgg ttccctattg acgaggctat caaaaacctt aaacgtggta
      481 gccataaatg ggccattgaa tcttgaaaaa aacagcataa gattgactaa tactcttcga
      541 aaataaaatt caaaccacat cagcgtcgcc ttaccatact caagtatagc ctgcggctag
      601 cttcctagtt tgctctttta ttttcattga gtataaatca agcgacttta ttcaaaaagt
      661 gctataatag aattagaaaa tcggaggaaa tattatgaag cttatcaata cgacaaactc
      721 acactcgcaa cttgtaaaaa gtcagctaga aagtaccgat gcaacccttg ttgaggttta
      781 ttctgcaggg aatacagatg ttatttttac ccaagctccg cttcactatg aaatcctcat
      841 ctcaaacaaa caccgtgcta ttcgtgagcc tgaaatcgaa accattcaag aatttttctt
      901 gaaacgtaaa attgataagg cctctgttga tgaagccaat atcaagacac tctactcaga
      961 gaaattaatt ggaatttcaa tcccaatcaa gtaagaaaat tgagtaaaaa ctcgatttga
     1021 gagaaagtcc aataagtctt tccataataa aacgcatagt agcaagagtt tctacaccca
     1081 ctattatacg tttttatcat tttgaaatct gctgctaatc aatgaagaag caaagatcaa
     1141 actaggcagc tagttacaag ttacgtaagc gcgtcataac aaggtatcta tcctaattcc
     1201 ccaacttcca gtatactaga taaaaaataa ttatcggagg aaaagtattg tactatgatg
     1261 attcaactaa gtgatttagg tcaagttcac cttgtttgtg gcaagacaga tatgatacaa
     1321 ggaatcgatt cactggctta tctcgttaaa acccactttg aattggatcc tttctccggt
     1381 caagtctttc tcttttgtgg tggacgtaaa gaccgcttta aagcccttta ctgggatggt
     1441 caaggatttt ggatactata taaacgcttt gagaacggaa aactgacttg gcccagtaca
     1501 gaaaaggatg tcaaagctct cgcacctgaa caagtagact ggcttatgaa gggcttttct
     1561 atcactcccc aaatatagtg gatttaaact agaatagtac acccctactt ctaaaacatt
     1621 gttagaaatc gatttgactg tcctgatcaa tttgtcctgt tcttgtttca ttttactata
     1681 gaacgatttg aaggcgttta tgatatttag ctgtacgaga gtcttttaaa agtgttttga
     1741 tggtttggat ttcttcttta gttgatttta tattactatt atataatgct tttttatttt
     1801 agtctagtat aaatagcgag aaatatctat cctatcttct agaatgtctt ccaaacgaga
     1861 aaactctcgt aaacaaagag gttttagagg cctatttacc gtggactaaa gttgtacaag
     1921 aaaagtgcaa ataagaaatc tccagattag gaactatccg tgagttctct agtctggaga
     1981 tttttcaata gacttcgtta ttggacggtt accaagttac tcaaagtaca gatttgaagc
     2041 tgcagataag actgacgaaa tcactttaat actaaatgaa aatcaaaaag caaactaaga
     2101 agctagcctc aggctgtact tgagtacggt aaggcgacgc tgacgtgatt tgaagagatt
     2161 ttcgaagagt ataaaacact gttttgaggt ggtggataaa tcggctgggt aaaaactcaa
     2221 tctcaggaga aaatgaagta aatctcccca caactataga aaaagatttg attctgctcc
     2281 tcacacaata aaatcttttt cttttattaa aaacgaatcg tttcacgtgt tttctcatat
     2341 gaggtaacaa agcgattggt tacaccaggc tctgccactt ccaatgcttg agaaatcttg
     2401 tcaaatgaag cgtgataatc aaattctttt tcaaaaatat ctaaagcttc gttaaatgct
     2461 tcttgaatgc gttcatcaaa tgagcgatag cggttagaat attgcaagag ttgctctgtc
     2521 aaagttgcat attgtacaat attataagtt tccgtttcta aagcttccat atcattcgtt
     2581 gcaatttcaa gaactcgggt aacagattca atgttaatca ttttttgttc taactcaacc
     2641 attaaatcct cggtattatt gcttgccgta aagaataact tcaagaaagt ttgtggaata
     2701 cctggcagat tgcgtttttc catgtatcgc ttgatagtat ggagacgatt gacataaaca
     2761 ttggcctttt gacgtgcatt aatatcatct ttctcaattt gtgtcaggcg ctcactaact
     2821 gaaatttgct catcttcaat atcttttagt tgagtttgta aatcctcaag attttcttca
     2881 agaactgaat aagcttgggt tggttcttct tgatttgaag ttacctcaac aatagctgcc
     2941 tcaaaactct ctaattctgt ctgaatacga cgaacatggc ttgcagctgt ctcaggaagt
     3001 aaataggtct tgttcaaacg tgcaatatct tctcccaata aagtattatt ctctttcata
     3061 tgttgaaggt aagttggaag agttgcaagt agattttcca ctactttctg agcagcaatt
     3121 tctcgagtaa aaatatcata caaggcattg atttcctctt gtgcctgtcc attctcatat
     3181 tcggcattat ccaattccaa ctgacgaata ttctcttggt ttttcttgaa tgcttcataa
     3241 agcaagtgga aacgcgcttc aatatccgtt tcaacaaaat gataattagc atcaattagt
     3301 ttacgataac cggattccaa atcctgtaat tgatctggca attctgtaga aagcgtcgta
     3361 accaaggctg gaacacgatc cacaatatga cttaaggcca aaatgtgatt ttctgtatta
     3421 tccaaaatca ctgcggcttc cacagggtca cccgatgaat tcaaggttac aaattgtgaa
     3481 aattcagatt ggatattttc taattgtttt tcaatttcat ccaaggcttg accatactgt
     3541 tctgaatttt cagcaactct atgctgaagt tcctcaaata aatccaaagc atgaagaaca
     3601 cgaccactat ttttagattc ttgcttctct aagtctgcca aagcattgcg aattgccgca
     3661 atatcttctt caatcaaagt aatttgactc tcaatttggt caatttgatg actggccttg
     3721 agaaaacgaa atgaatggtt ataaccttct gcttcaaaga gattattttc aatatcggca
     3781 aaagagttga gagataaatc gacccatttt tgattccatt cacggaaagc cacttgactt
     3841 tgtccaatca agtgcatatt ttttacagct tctacttcat catttactgg aagattgtat
     3901 agttcttctt ttctttcttc tagcgcctct aatctcccct cgtttcgctt acgtagaaag
     3961 attgccacta cataagccag aactaaaatg actgcaattg caaccattaa ataaattagt
     4021 tgtccattag acatatcaaa ctcctttttt acttgaaaca atcgtaacga ttatatcata
     4081 ttttttagac caagggaact acttctccct attttttaga catcaagtgt actatagaca
     4141 gcattttctt cgataaactc acgacgaggc tctactcgat cccccatcaa catatcaaag
     4201 attttatctg cttctgcagc atcatctaca gaaactctag ccatcaagcg atgttcggga
     4261 tccatggttg tttcccacag ctgatgatcg tccatttcac ctagcccctt ataacgctga
     4321 atagtcggtt tggtacgacc ttcactataa cgggctaaag cttcttggag tttgatttct
     4381 tgatctgcac ccggctggat atattcttta atctcgctcc caaccttgac accatagatt
     4441 ggtggttggg caatataaac ataaccagct tctaggattg gtttcatata acgataaatc
     4501 aaggttaaaa gaagggtacg aatatgggct ccatcgacat cggcatcggt catcaaaacg
     4561 agtttttggt aacgggcttt cgaaacatca aattctgcgc caaatcctgt tcccatggct
     4621 gtgaaaagac tacgaatttc ttcgttagct agaatcttat ccatacttgc tttttcaacg
     4681 ttcaaaatct taccgcgaat tggaaggata gcctgaaact cacggttacg accagatttg
     4741 gctgatccac cagctgagtc tccttcgacg atgaagagtt ctgtttcagc agggttatta
     4801 gaagaacagt ctgctagttt ccctggaagg ttggaaattt ccaaaccaga ttttttacgt
     4861 gtgacttcac gcgcacgctt ggcagccaca cgagccttgg cagctaaaat ccctttttcc
     4921 acgatacgtt tggcaatctg tggattttcc atgaggaaat cggagaaggc ttcactgaag
     4981 aggcgattgg taatcttgac cacttcgcta tttcccaatt tggtcttggt ttgtccttca
     5041 aactgtggat ttgggtgttt aactgagata actgcagtta atccttcgcg aacatcttcc
     5101 cctgttaaat tatcttcatt gtctttcagt aacttattct tacgagcata atcattgata
     5161 acacgagtca gtgccgtacg gaaaccttgt tcatgcgttc caccttcatg ggtatgaata
     5221 ttattggcga aactcatgac attttcatgg taacctgttg tgtactgcat ggctacctca
     5281 actgtaatat catccatctc accgtctgta tagattggtg tatcaaagat tacatccttg
     5341 ttctcgttga tatattcaac gtaactagca atcccacctt cataatgata atgcttggtt
     5401 tgttccaaac cttggcgctt atcagtgata gaaatttgaa gaccgcgatt tagaaaggcc
     5461 aactcttgaa tccgtttatt taatttatca aaatcaaagg ttgttgtttc agtaaagatt
     5521 tttgggtccg gtataaagtg aaccgttgtt ccagttctat ctgtatcccc aaccacctca
     5581 aggtctgcaa caacatgacc acgacggtat tcttggtaat gaatcttacc gtttttatgg
     5641 acatgaacgt ctaattgagt ggaaagggca ttaactactg acgaccccac cccgtgaaga
     5701 ccacctgaaa ccttgtatcc accaccgccg aactttcctc cagcatgaag gactgtaaag
     5761 acggtctcaa cagcaggacg gcctgttttt tcctgaatat cgactgggat accacgccca
     5821 tcatccacaa cagtaatcga atcatctggc tcaataaaaa cttgaatatg gctggcaaat
     5881 cctgccaagg cctcgtcaat tgagttatca acaatttccc agactagatg gtgaagacct
     5941 tcttttgagg ttgatccaat gtacatccct ggacgcatac gaacagcctc taagccctct
     6001 aaaacttgaa tttgactggc atcataatcc tgtgcctgca gatttttgat ttcttctgtc
     6061 atcttattcc tttttcttat atgtctaata cttgtcttaa attcacgata ctggtaaaca
     6121 agtgggtatc aagtcctgca gcttgacctg cttcgatatc aatcggccga tcaccaatga
     6181 caagaccaga gctaatctga tacttttctc ttaaataaag catggattcg ggatttggct
     6241 ttctcttaaa gcctgagcta gaagtcacca cttctgtaaa ataagctgct atagaggttt
     6301 tttctaaaat ttccaaaacc tgatcatttc gatgagagac caaaaaatga cggccacctt
     6361 gatttaaaat gtcttccaat aggtcagaaa ctccttcaaa taaaatcggg tgttcaagct
     6421 ctctggcttc attttccttg tacttttcta aaaaattctc taaattggga gcgaatgtct
     6481 caatcgcaaa aggagtagaa acctttaaag tttgatagac actgtcatgg tcttgtgtga
     6541 taccatacag tgccaatgtt tcaacaaatg cagctgttga agtttcataa ttatccagta
     6601 aagttccacc taaatcccag atgtaatcgt gatatttcat acccttcatt atagcatttt
     6661 tttatgaaaa aagcgatgat ttccctgagt tttccacata aaaaacgaga gaataactcc
     6721 cgttttactg atttttacca aagacatctc gatagagcat tcctgttcgt aaactctctg
     6781 cgtcccctcc tagttgctcc accaactcgt aggcaaaggc aagggctgtt gaaggacccc
     6841 gactggttgt caactgacca tctaccacta ctgtttcctt gacgtagtga ccatcaagga
     6901 tttgctcttg aacgccgtca taacaagtgt atcgcttatt tttcaatatc tctgcttgat
     6961 tgagggcaat tggtgccgca caaatggctg ctagtttctt cccttcttgt tcgaagcttt
     7021 gcaattcttg aatcaaggtc tgattatcac gtaaatgtgc agaaccaggc atacctccag
     7081 gaagaacaat catatcatag tctgataaat ctccatcaaa gacatgatct gctcttactt
     7141 ggattgcatg cgaacccgtt acttgctctt caaaaccaac catatcacat gtgatattgg
     7201 ctcgacgcaa gacatctaca actgtcaagg cttcaatttc ttcaaagccc tgagctaaca
     7261 taactgctac ttttaccatg attttctcct tatttaattt gttttaatac aacctttttc
     7321 cgtttgaatg ggacttttcc gctcttttct tcagctagat tagtctggta actcatcgat
     7381 aaaagcaaac caacaccaat cagattactg ataatagctg atcccccttg cgaaatgaaa
     7441 ggcaagggaa tccccgtcaa aggaagtagt ccagtcacag caccgatatt ctcaaagatg
     7501 tggaagagca acatcataat caaacctgtg gaaatataag tgtagaactg gttatttgat
     7561 ttaagagtaa tcttcaacat acggtaaatc aacatgagat agagggcaat aaccaggaca
     7621 gagccaataa agccaaaatc ttctgcaata accgtaaaaa tcatatctga ctctcgaact
     7681 gggataagca gattcgaagc attaaatccc tgaccaaata agccaccact cccaatggca
     7741 atctgccctt gagcctgctg gtaagtcgtt gtttgggcaa actcaaaggg attgagccaa
     7801 gccaaaatcc gattgatttg gtaggtcggc attccaatct ggtgaagaaa agctcgtccg
     7861 tccttgctaa taaagatagc taagaaacca gcaactcctg ttacagcagt cacaaatact
     7921 gggataataa ttttccaaga aacccctgat aataaaacga ttcctgagaa aatggctaca
     7981 aaaaccaaag ccgtccccaa gtcactttga agtgctaaaa gaactaggac tggaatggta
     8041 aagagaatca tccagaaaat taacaaaaag tccagcgaaa ccgtgcgtct ccattcctta
     8101 tgtttctttg taaattggac aatgacacga gccaacatga ggatatagga tatcttcata
     8161 aattctgacg gttgaaatag ggtaattcca tttattgata cccagttttt ggcacccgtt
     8221 gatgcaacta agcttggatt ataaaataca atcggcaaga tcataagtcc caagcctaaa
     8281 atatatagaa agggggtcac cttccaaaga aattctgtat taaagagcat gaccacaaaa
     8341 ccaatcacaa gccccaaggc aatccaggcg acctgctgcc ctaaaatggg cagaatatta
     8401 ttgggataat catgactaac ggctatatag atagccacca caccgatgac cagtagaaaa
     8461 aatactggca agagcaaact ataatcaact ctagagtcga gagaacgttt catatatact
     8521 aaccttatac tttcatacaa tactatttat caaagttcat taaaaaatct atcaatagcc
     8581 tcgtcaactt cggatcgaga gatggtttta atagtcgctt cttctgctag agatgctact
     8641 atttgtttgc cgtatcgttt tccgatgatt ctcctatcca aaataagagt taaggaacgt
     8701 tggtattcac gtctcatact tcttcccaaa gcctgtttta aacgaataat ggccattggc
     8761 aattgataat cataaaaggc atttttccct tcttgattca gttcttgatt aatctttttc
     8821 gtcaagggtt cttgaggatt ttggaaagga agcctcggta caacttgaat cacaaaagga
     8881 tggcttgaaa aatcaactcc ctcccagaaa cttgctgcac caagcaagat ttgttgttca
     8941 cctttttcaa agcgtttctt tagctgatga acatccccat ttttatactg ggccaagtgg
     9001 ctaactgtaa gtaaatccga tactgctaga agcatgtctt tagcggtaaa gagaaccaaa
     9061 atcggttgct ggaaagcttg aatttccact agtaaagcag ctacctctct ggcatagact
     9121 tctaaggagg tttctgttac cagagggaaa tctttgacca taaccacttc ttgttcctgt
     9181 tttccccgag attcaatctt gacaaatttg gcttcaggat agcctaaaag gtctgccaaa
     9241 gaaaccctct gactaatctc aagagtagcc gatactccca agacttggca actctcagga
     9301 agtaaagagg acagaagagt acggcatgat tttgtagaag aaatctgaat tttcttttga
     9361 ctcgtttcag ttacttcaag ccagtaatca ccttcagctg taaaatagcg aaccagctca
     9421 tcaaagcctt ctacttctaa ttctgaaaaa tactgatgga gattgtccag agaatctaag
     9481 atatttttcc tagatttacc agactgaaat tgttctatca agtagagaca ctcaaagcga
     9541 atactttcta gtatccgttg ttgaaccctg ttttcttctc ctactaaagc cttatcaatt
     9601 aaatcgataa tagattgtat atcgtaggtc tcttgaagca gattttctag agctaacaaa
     9661 atcttttgga cttcatcaat aatcagtaaa cggtcactga caaattcagg attatcttca
     9721 agtctggtca cgagataggc atgattagtc actaaaagct tgcaagtctc tgccctttct
     9781 tgactacgtt tccaaaaatc ttccgtcaca aataagctct gggatgataa attcccatca
     9841 tgacgaaggt ctgctagaaa atgttggtaa cggtagagtt gcccgatttc atccaaatct
     9901 cctgtctctg tctcagtaag ccagaccaag acttgcattt taaagcgtct aaataagcga
     9961 ttttcatcat tttcctgcaa ggaatgataa aaggcatcca acttcagata attttgtggt
    10021 ccctttaagc tatgaatatc tgtatggaac acttccttga ggcgtttacc ttcttcttcc
    10081 atgatttgat tttgaagaat ctttgtcgga acactaagaa caatttgtcg ctctttggat
    10141 tgagataaag cgggtaagag atagccatag gttttcccaa tccctgtcgg cgcttgaatc
    10201 agagagacag gttcatcttt caatagcaag ccaacctctt tagcaaaact ttcttgttcc
    10261 tccctcactt caaggttcaa cagagaaata tttttagaaa agtcttgaga tagttttcgt
    10321 ggctccagag aagctgccgt tttcttaaaa tacagacctt gaacttggac caagtctgga
    10381 gaactcagga tagattggtt gcgataagtt tcctcaataa ccaggtagga ctcatatagg
    10441 agagcgtcag ccatttccag caagcgttcc aagagacctt taggaagctg agtcatcttt
    10501 tcccgtaaaa aaagaagtaa ttctgctgta gcttgggcat ctgaaagggc tgtgtgtgcg
    10561 tgtttaagag gaattcctaa ttctcgacac aaaatcggca agctatattt ttccagttca
    10621 gggaaaaaga cctgggccaa ttcgaccgta tcaacacgag ggtttcttag ctcatagcct
    10681 tcaaaaaata aattttccgc caagagatta gcatcaaact gaacattatg ggctacaaaa
    10741 atcccatcct ccaccaagtc aaatattttt ctggcaactt gcgaaaaatc aggtgcttgc
    10801 gccagacgtt ggtctgtcaa tcctgtcagt tctttgatat gaacatccaa gggttcatgt
    10861 ggattgacat ccgtcgtata gtgatcgacg atttctccgt cctcaatcac gacaattccc
    10921 acttggataa ttttagcctt actacctgtg ctagttgcct ctaaatccac cacaacatag
    10981 cgattaccaa tcgttttcat tataaaaaat tataccaaaa aaagggccat ttggcacctg
    11041 caaacatagg ataattttca aactcaagaa cactactttt cttaaaaatc ccatcgaata
    11101 gagcattcta gcctgctgat ttttgtaaaa tagtgaagaa atacgaaaaa ttgagagaag
    11161 aaatgtttgc atcttccttc tctcaacgaa tcatgtattt tatctaacca tgtcaggatc
    11221 gtagtcataa aatcctgtat caaggaaacg gtttttaggg tgaagtttac gaacttcttc
    11281 atccagcaag aaggcttgat catggctaaa gttgccctct tgaatccaat tacgcgcttg
    11341 gataaagagt tttgcaatct caacaaagtt ctgaccagga gtgtagagcc cttctagttt
    11401 ccagcgagta aagccatgct ccaccaattc tgttaatttg atcatcaaat caaggtcatt
    11461 gttggcaaag atatgggtcc catgattatc ttcaaaaatg gaatagtggc tctctggatc
    11521 acttggctca gccaagaaga ggtcacgttt atgcgtcttt tcatcatcga tatgtgtaaa
    11581 gttatagtag ttttgcaaga gtggacgttt agaatgatgg atgacgctag caccgtaaac
    11641 caaaacttca gcaggaattt ccaaaatctc tggcattttg aaaagttcag ctgatggaat
    11701 ttcacgcgcc aaaacagcct cagatgcgcc agccttttgt ccccagaagt taatctgacg
    11761 actgctagtt accatggttg aagcatcgta gatggtctta aatgaataac catcgcggtt
    11821 aactacgtaa aagacgcctg catccccaat cgtaatatag tctgtcttga tttcttccaa
    11881 gaagtctaag aaaggcttga tacggtccat catatcttgg tgcatgagag cattgaccgc
    11941 aacgagcaat tccttaccag catcatgaac caacttagcg atttcacgta attggtcata
    12001 actaaaggtc gttggcagac gaaggccaaa atctttctca ccgacataga tacggtctac
    12061 gccagcttcg agtagttgtt caacttgttc aatactttca gcagttgctg taatgacaat
    12121 cttttccata agaaaaatta taccacattt ctccaaaatc agccatgctt tgaaaatgaa
    12181 aagggacttt attctttttg taacctttct gtaataattc tctgccgaaa aaatgataaa
    12241 ataggtatgt actgttaagg agagaattat gcccgtaaga aaattacaat cctatgaggt
    12301 agactatcaa gaagaattaa accagcagct tcctcattac caagcttata cacctgaagc
    12361 gcaatctgat gccaatctca aggaaatcct attttttatt aatatcgctg ttttttgtat
    12421 ctgtattgct atctttagtt ttatcttttt agcattaaaa ttatcaactg ctcttgcctt
    12481 tgccgcagca atcggattca gcttacttgt tttaaaagtt caacggtcta ttatcaaacg
    12541 aaaacgtaga agataaatcc aaaatatcgc cccagttgga gcgatatttt tattttttct
    12601 ttttagatgg tgtctgaatg gcaatcttca cttcaaagat tgttcccttg ggtttattat
    12661 ctttgacagt aacagttcct tttagagcat ctacaatttg cttggctagg gataatccta
    12721 aaccaaaacc acctttttgc cgagttctag ccttgtctac tcgataaaaa cggtcaaaaa
    12781 ttttcttttt atcttctgtc gaaataccga ttccattatc agaaacaagt aaataaagat
    12841 tgcgatcggt cgccgagata agaaaatcaa tttcaccatc ctcctcagta tacttgacgg
    12901 cattatcgaa aagaatggtc atcagttgtt tcagaagaag ctgatctgtg acaattgttc
    12961 gatggatacg attttcaaaa cggaagacac gattattttc cgaagcaatc atctcgtagt
    13021 ttgtgaaagt tgtattaaaa aagctagttg gaacttctgc aagctccggc ttaatcccat
    13081 catctctccg agctaagttc agcaagcttg tcgttaaaaa acgcatattt cggacttctt
    13141 ccaaactcga tgcaatgctt tcgctcacat ccataatggt agcttctggc ttacgaaaaa
    13201 gggtctctaa gcgattttgc aaaactgcga gtggagttcg taactcatga ctggcatttt
    13261 ccacaaaaga ctgttgcttc tgcatactct caagcagggg cctaacactg accctagcta
    13321 gatagagact ggcaagtaaa gacaaaatcc agaaactagc catcacgacc acaatcaatt
    13381 gctcatgctt ttgactagcc tgctccaact gactggtatt aatcaagaca gcagcatact
    13441 tgatattggt tgaaaccgaa ctaatattgg tctccatcaa aatcacacga tagatttctt
    13501 cctgcccata gctattaaaa acctgaatct ggtagatatg tcctagttct ttcttttcta
    13561 acttaatctt atccaagccc aaaaatcgat ttccagaaag aagttgagta aagtccttat
    13621 caaagagaat gacttccgta ttggaactga cattaggttt tatttctact ttactagcgt
    13681 ccgccctagc attttctaaa tctttaatct cttctgttgc cctatttata gccagctgaa
    13741 taactgcttg aggattttca ctcagtccat gaagcttatc gtccaccgaa gtataaagac
    13801 tcgaatgcat gacttgtaaa ataatcagag tcattgtaga aaaaatcagg gtgaagacac
    13861 cgaagttgcg gataaaataa ctaaagtcat ccgcatacca tgttttttta agtttactga
    13921 acatctttta aaagataccc aacactacgc aaggtttgca aattctctgc aaaagtggtt
    13981 ccctttaatt tcttacggac ttttgaaaca tagacttcga caaccgaaat cgttgtatca
    14041 ctatcaaatc cccatagacg gtcaaaaatc tgcgtcttag gcaaaatcac attttgattt
    14101 tgaaggaaat aaactagtaa atcgaactct ttccccagca attcgacagg agtatcttca
    14161 actttaacgg tattggttga taaattaacc acgatattcc cataagtcaa ggtgttttca
    14221 ttaaacttcc ctgaacgttt gagaagggcc tgaatccgca ttttaagttc ttctaggtag
    14281 aaaggtttgg tcagataatc atccgctccc agttcaaatc catgtccctt gtcatccaaa
    14341 ctttccttgg cagtcataat cagaactggt gtcgtaattc ccttttcacg caattctttt
    14401 aagacttgga aaccattttt ttctggcaac atcaaatcca gcaaaatcaa atcatagaca
    14461 ccactctcag cttcgtagag accttcttct ccatcaaata cctgcataac atccgcaaaa
    14521 tcgtctaaaa agtcaaatac tgaatttgac agacctaggt catcctcaac caataagatt
    14581 tttatcatga gaaactcctc cttattaaaa ctattatacc aaatttgcct taaaaaaaac
    14641 tcaactctct gcattttaca tgagatagct gagttttctt tttattttag gcttatttat
    14701 gcatttccgt attgaagaac aactgcttcg actgcagctt tttcacggct aatcaagtca
    14761 acacgtgctg caatttcctt gattcccata ccgatgttac ggctaagagc aaggtcagaa
    14821 agttgcggct caaagaactc cttgtattcc gccaagcgtt gctgagtctt aaatacatga
    14881 gcaggaagga taacaaagct atcaaagctc atatctcctc caagggctgc cttaatccaa
    14941 gcccagtttt cacgcgccca agaccaagct gttttctgag ttgcttgatg agctaggaat
    15001 tggtaatacc aagcagacaa gtcctgtggt ttgaccacaa atttgtcctt ccaagaagta
    15061 atcaagtttt ggatattatc cgcatctgta ctgtatgcaa gagctgctgc caactggcgt
    15121 ttaaagacag catctgttgc gtgagtataa gtatcaagat aaagtgctaa caagtcttta
    15181 gtctcatgat gtttcatctc attaatcaga acttgtgaac gaatagctgc tgggagtcct
    15241 gcaagattct ccttgtgtgt tgcgaagatt tggctagcga cttgactagc ttctgcatca
    15301 tttgagcgaa tcatcatcga aacagccagc tgacgaacca attcatcctc atctgattct
    15361 ccgtctttag cttcaaaacc aagacggtca tagttatgac gagccaattt agcaaccagt
    15421 cctttgaagg ctgtttcagc atccgttcct tcatcaataa agcgctcaag ggctgaaatc
    15481 acttgagaaa cagctgaaac caccagataa gactcttcct tagcaagttt atcaagaact
    15541 ggaagcaagt ctgcataaga aatgtgccct gcctcagcca acaaacgacg ttcttgaaca
    15601 atttgcagtt tgcttgtgtt atcaagtgtc tctagctcag caagaacagc ttctaacaag
    15661 tctccttgat agtcggtaat atagtgggca gtattttcag tgttgagacg aagagctcct
    15721 tcattttcag caagaagagc tgcgtagcca gggatttcga tactttcagt ttcgagtgta
    15781 tcaggcaagc ctttccagtt gctattgagg ggcaccaccc agagacggtt cttgtcttcg
    15841 ttctcaccga tgaagaattg tttttgtgaa atcttcaaga catcattttc aactttaaca
    15901 gtaagaactg ggtaaccagg ctgttccaac caagaatcca tgaaggctgc gacatcacgt
    15961 cctgacgctt gaccaagggc atcccaaagg tcactaccaa tggtgttgct gtattggtgt
    16021 ttttcaaagt aggcgtgcaa acctttagca aaatcagcat ctcctagcca acggcgaagc
    16081 atgtgcatga gacggcttcc tttggcatag acgatagcgc cgtcaaagag tgtattgatt
    16141 tcatctggat gtttaacttc gacgtggaca gactgaacgc catcagtagc gtcacgttca
    16201 agagcaagag gtactccacc tgtttggaaa tcttcaaaga tattccagct tggttcgatg
    16261 gtatccacac agacgtattc catcatatta gcaaaacttt cattgagcca aaggtcatcc
    16321 caccatttca tagtcacgag gttcccaaac cattggtgag ccaattcatg ggccacaaca
    16381 agggcaactt gttgacggct agcaaatgta gagttctcat cgacaaccaa gtaaacttca
    16441 cggtaggtca caagacccca gttttccata gcaccagctg agaagtcagg aagggcgatg
    16501 tggagagatt gaggaattgg gtacttaact ccatagtaat cttcgtaaaa ctcgatagag
    16561 cgaacagcga tatccagtga gaaatcaaga tttgaaagtg gatgtgcttt ggttgagtag
    16621 acacctacca gggtaccatt tttagtttta gcggtcaccc cttgcaaatc accagcaaca
    16681 aaggccaaca agtaagaaga catgcgaggt gttgtctcaa acttccagat acctgtttcc
    16741 ttacggtttt caacatcgat ttctggcatg tttgacaagg ccaattcacc ttctgcttgg
    16801 tcaaagcgaa gagagaggtc aaaagttgct ttggcttcag gctcatccac acatgggaaa
    16861 gcttcgcgcg caaaatggct ctcgaactga gtagacaaga cctccttctt gactccatca
    16921 actgtataat aagaagggta aatccctgtc atgttgtctg taattttacc agaaaaggca
    16981 agaaccaatt caacttgacc agcctcagcc aattcgatat gaagggcttc attgtcatgg
    17041 tcaactgtaa atggacgagc ttgacctgca acttctacag aggtgatttc caagtctttt
    17101 tggtggaggg agatgcggtc actctgtgct tgaccagtga tggtcacttt cccagaaaaa
    17161 gtcttggtct cacgactcaa atctaaaaat aaatcataat gttcaggaac aaattgctta
    17221 ataaaatgtt caactgcttg catagttttc tcctattcta agtttaagag ctgctgctct
    17281 tcttcaaaca aacttattat atcatatttt gcttgagaaa aaaggattgg acagcgattt
    17341 ccaaaacttt cttccttcta atagtctaca gtgggtagac cttgcgaaat tcttctaaaa
    17401 caaccttgct ttcaggtgta aaagtcagcc ctacttcacc caaacagtct gtgaaaaagt
    17461 cctcatgagc ctggcgccaa taggcaagtg atttgtctcc ctcaccttcc ttaaaggcat
    17521 gttgcgcaga gacttgattg aagagttcaa cagaaacctt tgtaatttcg acaatgcaga
    17581 cagactgatt ttgactatct aaaatgacat cgaaggtccc tacttgggga agtggttcgt
    17641 cttctagtac atagaggtca taggctgatg ctgttgctgt cttttctcct ttaaacacca
    17701 aatccgctaa aaggtctggt tcaactccaa aagcccaagc atcgatttca tctccgatca
    17761 aaggattgat ttgcttgtat ttattccaca tttcttgcgg tatcatgggt actcctttgt
    17821 aattttttac tttcttcttt tatgtgttta agatgatctg gatggtcaat ctctaaatca
    17881 aaaatctctg gaatagaact gtagtggata atgcacttga tacccaactg attcattttt
    17941 tgtatgaaag aagtattcag atagcctgct acagcaaaat taatcttgtt ctttcttgct
    18001 ttatcctgca tatctcttag catatctaac attattggac tttccatatc atgccattga
    18061 ctgtttctca tagtcgcaaa aacaaaggaa gtcaaatcat tcattccaac tacaatcttt
    18121 gaaatgcccg tttccagtat actagataag tcaaaatacg ctgacggtaa ttcaatcatc
    18181 gttccgactt tcccagtaaa gccatactga cgcaatactg taatagcttg ttttaattgg
    18241 tcggcatcat tgacagaagg aaagataaca gatagattgg ggttggtttg ataaacttct
    18301 gtaacgacat gtgcttcagc ctgaaattca tccaaacacg ccagtaaacg tctggttcct
    18361 ctatagccaa acaagggatg cccttcgtca aaaaactctc tagtccccac taaacaattg
    18421 gcttctgtat tcgttaattc agaaaaacga taccaaactt ccttacctaa gtaaaaggag
    18481 caaatagtat caagataatc ttttacaaat tgctgacaac ttgctaatat gatgttttga
    18541 ttgagctctc tcaataagta ttccccacga atcatgccga cgtggtgaaa tagttgagga
    18601 taaatttttt caagaatttt ttcgccacta agggcaagtt gatttctcat agccattcac
    18661 ctcgtcttaa aagatacaat atcatatata attatatcaa aatttcctct agttcaaaag
    18721 cttcataagg ttcagataac tcatatccta aaaattctgc tacttttttg gaagcctcat
    18781 tatgagcatc ccaaagtgga aacatatctc tatttaaact ctctagaatc attgcagcac
    18841 caagcttttt agcaagtcca tttccttgtt cgtttggtct agttgcaact tccacttcaa
    18901 ctgctttacg gtaaactaac cctgaggaaa tcccagcaat cagttcatta tttttaagaa
    18961 tcacaaagcc aaatccacct tttaaaacaa aatcctgata ggactcaaaa tccccctgta
    19021 aatcctgtga ccattcttcc gtagaaaagc agttataaat atgattatca ataggcacaa
    19081 tattgtaacc ttcctctaaa tgagtaacta gattatttaa aaattcaact tgaaaatttg
    19141 ccttatcttt aaaagaatag cgagtaaaag aatttagccc cacttttcga tgcagaaaat
    19201 cttgccaatt agtattttct gaaataataa tcttataatc taaaccatat tttctaacaa
    19261 aatcttccca aaatctggaa tccaactccc ctgctaggta tagaaaattc ccaacatcat
    19321 aaaagcttgt tgtcctatca ttgtttcggt agacagttcc aatttgagat ttaagaccat
    19381 agagaaccat atttttcttc catgttttaa atagttccat tatccctcta cttcaccttc
    19441 caattcatgt aagaagtctt gtccagttct ggaaatccta ataattcaga cttaaccttc
    19501 aagactaatg gcgatgcatt ttcttctgta atttcttgaa tatccatcca aatatatcca
    19561 agtgaatcat tcgcaccatc agacacagct tccgaagtcg taacttgagg tgcactctca
    19621 ttcatttcaa catcatacaa ggccatgaca tggtgaacca taaaatttgt taactcttct
    19681 ctgacgaaaa catcgtagat tcgaggatta gagtagcttc taacagtaaa tcccgtctct
    19741 tccataactt ctctagtcag cgtttccgtc agtccttcac caagttgctg actgcctcca
    19801 ggtagatcat accgatgttg ataagggcct ctcgtttttt caatgcaaag taactttcca
    19861 ttttcaaagc aaacagcgta gactccaaag tgttttttga tttccatcca actcctccta
    19921 cttcaaagac cagccaccat ctattgtcaa gatttgtcct tgcatggcgc tcgcttttcc
    19981 acttgctaaa aaaagactaa gctctgctat ttcctctggc tcaatccagc gcttgattgg
    20041 ggtttcacta gccacccagt cagccaaacc acctggttca aaatccgcag cggtcatagc
    20101 tgtcttgact gctcctggag cgataccaaa gacctgaatc ccagcttcag catagtctag
    20161 agccaactgc ttggtgaagc cagccaaggc atgcttggat gaagtatagg cgtgaccacc
    20221 tccacctgct aggctagaag caatggaaca catattgatg atgattccct ttttattttc
    20281 cagcatttgt gtcaaataat accgagtcaa ctctactgga ataatgtagt tgatttcaaa
    20341 aatctcttga atgtcctgcg ccgtttgttc caacagtggt ttgtaatcat ccaaaactcc
    20401 agcagtatta cacaaaacat ccacctgagg gcaccagtca aaaataggtt ccaagtccaa
    20461 ggtcaaatct ctctgtaaaa agtgaaaatc accctctaag agtggctttt caccttggtc
    20521 aactccataa acttgatagc ccttctctaa aaagaggcga gcttgagcca atccgatccc
    20581 tgaactcact cctgtaatga gtacacgttt agtcatgcac ttctacccaa tccgttgcca
    20641 aaacatcaca aactgtcggg ctccacatgg aaaaaccttc tccttcgcca gaaacgttga
    20701 ttaggaaata aggtgtcatt tcaagtgcaa gcccattttg ctcgatggta tcaaagagtt
    20761 ggacatagtt ttccgcacct ccccaaccag ttcgtacata ttttctctta gcctttaacc
    20821 caggcaggat ctcttcaaat gtcatgtttt tctcctttaa ttctacattc ttcatttaat
    20881 tatagcaaaa aaccgcttta tacggctttt tgaatgtgag ttattcaaac ctgctactac
    20941 ttacggcaaa ttattccctg cagcaagata aatttcatac cattcttttc ttgttaagct
    21001 aaagtttgcc gcttggctaa cttctctcaa gtgcttagga tttgtggtac ctacaactgc
    21061 ctgcattttt gctggataac gcaatatcca agaaatggca atagttgaag aggttactcc
    21121 atatttaata gctaaacgat caagtacttg atttaaagct tgaaatttct catttccaac
    21181 aaaattccct ttaaaatacc cgaattgtaa gacagaccat gcttgaatga ccacatcgtg
    21241 taatttgcaa tattcaaaaa tgctgccatc tcgcatagct gcttgactat cttccatatt
    21301 aacatgaaaa gctgattcaa atcctggagt aaaagccaca ctcaattgta gctgattaac
    21361 agctaacggc tgcttgacat cttttttaag caactccatc atcataggat tttgattaga
    21421 aactccaaaa tctcgaactt taccttgttt ataaaggaga tcaaaggctt ctgctacttg
    21481 gtcagattcc atcaaagcat ctggtcgatg aaggagcaag ctatctagat gatcaatctt
    21541 caatctttgc aaaataccgt ctactgattt tataatatag tccttagaaa aatcaaaata
    21601 ggtaaattct tcaatgcgaa tgccacattt ggactgaatc cacatctttt ctcttaaatc
    21661 tggacgattt tttaggacaa gacctaacag ttcttcacaa cgaccacgac cataaatatc
    21721 agccaagtcg aaggcattga ttccaacaga aagtgctgtt tctacaaact cttcaacttc
    21781 ttttacagac ttatctttta ttctcatcat tccgagaaca atttctgata attctttgtc
    21841 atcttgacca agagttatgt atctcatcaa atttttctcc tttaatttct aacattcttc
    21901 ccttcattat aacaaaaaac cgctttgcaa cggctttttg actatacttc actccatttt
    21961 atcttcttaa acccatggaa caagagaaaa atgccaataa agaggacagc taaaggaata
    22021 acttttgtaa ggaaaacatt tgaaattccc atccactcat aataacggag cagagaaccc
    22081 accacaagat gggcaataat catactgaca aatggacgaa agaccgcttc tttccaattc
    22141 caaataccga taactagcga aatcgtaaag acagacaaac tatcccaggg atccggaata
    22201 taaaaggctc cttcttgtat gaagcttgcc attcctacat atcctaaaac aactagaaga
    22261 actatagtcc caacaacaat gtaagtgcca aatttcattt taggagaatc ttggactaaa
    22321 cttcttcgta aaattgtggc cacaagtcca aatccaatca gaaaaataag aagttgccct
    22381 aaaaatgtga gcaaattgac tgttaagaga ggacctttag aaaaatcact tagtagttga
    22441 taataacgta ataccgccag gacaagaatt ggcgtcaaaa gggactcttt gatagaactg
    22501 cgaggtgctc ccttgagaat ctctttcatt atttttttag gattcttacc tagataatcc
    22561 tctgcactca tgccatctcg ttctgcttct gagaaatcta gcatcatcaa atagatctgc
    22621 tctctgagat agtcttcatc atagagaaat ccagcaagat taaaactttc ccacaactcc
    22681 tcaaaatact tttgattctc ctcagaaaac tcatgtagca aagcgcttgt ttcttcgtaa
    22741 tacttcattt tcttcatggt ttaaccccca ttcttaatcc cttctacttt ttgactcaaa
    22801 tcgtcccatt gttgccaaaa gactgagaca cgctcttctc cttctttcat taatgaaaaa
    22861 tacttccgat ctggaccatc tggcgacggg cgcatgtcgc ctcttatcca ttgatttttt
    22921 tctaactttt gcaacaaagg ataaatagtt cctggaacga tagtatcaaa tccagcctct
    22981 cgcaaagtct gaaccaactc ataaccatac cgctcttttt gaccaatcat atccaagaca
    23041 caaccttcaa gaacaccttt taatagctga gtttctttca tcacttctcc cttctaatct
    23101 attttgtaat acctactagt aacttcacct atagtatatt acttctacac tagtttgtaa
    23161 agcataatag ttaatactct tcgaaaatct cttcaaacca cgtcagcgtc gccctaccgt
    23221 atgtatggtt actgacttcg tcagtttcat ctacaacctc aaaaacatgt tttgagctga
    23281 cttcgtcagt ttcatctaca acctcaaaaa catgttttga gctgacttcg tcagttctat
    23341 ctacaacctc aaagcagtgc tttgagcaac ccgcggctag cttcctagtt tgctctttga
    23401 ttttcattga gtataaataa aaaaacagaa ctagtctgaa ctagtcctgt ctacttttac
    23461 ccaatcacac ttccatttgg tacagctgga tcaactgtga gaagggttaa tttgccatca
    23521 tgttcagctg agagaatcat accctggctg acatattttt tcatcatttt acgtggtttg
    23581 aggttagcaa cgatttgaac tttcttgccg accaattctt gttcatttgg atagtatttt
    23641 gcaattcctg aaagaatctg acgatcttct ccatcaccag catccaagcg gaattgaagc
    23701 aacttatctg aaccttctac tttagacact tctttgactt ctgcgacacg gatttcaacc
    23761 ttgtcaaagt cttcaaactt gatttcatcc ttgtttagtt tgagctcaac ttcgtccgga
    23821 ttccattctt tttcgactgc tggtttattg ccttccattt gttccttgat ataggcgatt
    23881 tcttcttcca tatttagacg tggaaagata ggtgttcctt tggcaactac agtcacatct
    23941 gctgggaagt cagccaaact caagttttca agactagaaa cttcttccaa accaagttga
    24001 gtcaaaactg cacgactagt ttccatcata aatggttcaa tcaagtgagc aactacacga
    24061 atgctggctg ccaagtggct catgacactt gccaattggt cacgaagagc ttcatccttg
    24121 gccaagaccc atggtgcggt ctcatcgatg tatttattgg tacgagagat cagagtccag
    24181 actgcttcaa gcgcacgtgg atagtcaact gcttccatgt gtgtatggaa gtctgcgatt
    24241 gattgttctg caacctcagc aagaacatga tcaaattcag tcacaccttc tacataggca
    24301 gggatttgtc catcaaagta cttattaatc atggaaaccg tacggttaag gaggttccca
    24361 aggtcattag ccaattcata gttgatacgg ccgacatagt cttcaggagt aaaggttccg
    24421 tctgaaccaa ctggaaggtt acgcatgagg tagtaacgaa gtggatctag tccataacgc
    24481 tctaccaaca tttcagggta aacgacattc ccttttgact tagacatttt tccgtctttc
    24541 atgacaaacc aaccatgggc aatcaaacga tcaggtaatt taacatccaa catcataaga
    24601 aggattggcc agtagataga gtggaagcga aggatatctt ttcctaccat atggaagact
    24661 gttccattcc agaacttgtc aaagttacca tgttcgtctt gagcgtagcc aagagctgtc
    24721 gcatagttaa gaagggcatc aatccaaacg tagacaacgt gttttggatt tgatgggaca
    24781 ggcactcccc atgtaaaggt tgtacgagat accgccaaat cttccaagcc tggctcgatg
    24841 aagttgcgta gcatttcatt aaggcgacca tctggcgtga taaattcagg atgagctttg
    24901 aaaaattcga ccaaacggtc ttggtatttg ctaaggcgaa ggaagtatga ttcttcagaa
    24961 acccattcaa cctcatgacc tgatggagca ataccaccag tcacatttcc agcttcatca
    25021 cggaaaactt ctgccagctg gctttctgta aagaattctt cgtctgatac tgaataccaa
    25081 ccagagtatt cacccaagta gatatcatct tgagcaagta agcgttcaaa gacttgtgcg
    25141 acaacttttt catggtagtc atcagttgta cggataaatt tatcgtatga gatatctagt
    25201 aattgccaga gttctttaac tccaaccgcc attccatcaa cataggcttg aggtgtaata
    25261 ccagcttctt ccgctttctg ctggattttc tgaccatgtt catcaagacc tgtcagataa
    25321 aatacatcgt agcccatcag gcgtttgtaa cgtgctagga catcacatgc gatagttgtg
    25381 taggcagaac cgatatgaag tttcccagat ggatagtaaa tcggcgttgt aatataaaaa
    25441 tttttttcag acataatttt tcctttccag gcaaatgaaa cctgtttttc taacacttca
    25501 ttatatcaca tttttaatga atttcaatag ggaaatccat acaaaaacaa gatagacgag
    25561 tgtccatctt gttgatctca ttcataacga agggcttcaa ttggatcaag tttcgatgcc
    25621 ttgttggctg gcaagactcc aaaaatcata ccaacactag ccgaaactgc aagactaaat
    25681 agggcgactg ggattgatac tccaacttct ataccttcta ttaaaccttg cagtaacaaa
    25741 cctgctaagg cagttaaacc acttgcaatt gtcaagccaa ttaagccacc taacaaggtc
    25801 aaaatcatgg attcaatcaa aaactgaatt aaaatattgg cacgtgttgc acccaaagcc
    25861 ttacgaagac caatctcacg agtgcgctct gtcaccgaaa ccagcatgat gttcatgaca
    25921 ccagttcctc caacaaagag agaaatccct gcgatggaac taataatcgt cgtcataaaa
    25981 ctaaacgatt gttgaatttc tgcaaataca agggactcat ctgccacctg gtattctccc
    26041 tgttgtaagc ctgcaagctc tgtcattttt cgtgccagtt ctggacccag agttggggtt
    26101 aaactggtat cattcactcg aaagacaata ctagctattt catctacatt aaaattcgca
    26161 gcaagggaga tattggtagt aataggcaag ccaccaaacc catatatttt tgatctttta
    26221 gcctccggac tagtataaac cccaatgacc cggtaactaa atccattgac ttctacaacc
    26281 ttgttaatag cctcttgagg agattcaaat aaactaatgg acaattcctc atctagcaaa
    26341 ataacacttg caaactcttt gaaatcttgc tctctcagac tacgacctgc aataatttca
    26401 ttcttaacag cgtccatgta agttctgttt ccacctgtca aattagcatt ctcaaccttt
    26461 ttatcttgat aggtcaagat ggcattcgtt gaattggtta catagtaact atccactccc
    26521 ttcagtttag ctgcctcttg gacccaggat tcttgcggtt ttggcggttc aacaggaact
    26581 tcctcttcct ttccagaaac cgtaaaagct gattgtttct gagtaaaaga cccatcttta
    26641 ctttttttag gagagaaaaa gacgctaata tttttctgag atttagtcat atctttattg
    26701 acttgacgag atagggaatc acccaaagcc ataatcacaa caactgatga aacaccgata
    26761 ataatcccaa tcatagtaag caaagaacgc atcttgtgag ccatgataga tgaaaaggca
    26821 aatttcagat tctgcatctt agttttcctc ctttcctaac tgagcactgt cagacgaaat
    26881 gaccccatcc cgaatgacaa tctgacgttt ggcataggca gcaatctcag gctcatgcgt
    26941 taccatgata atggtttttc cttctttatt caaatcaacc aataattgca taatttggtt
    27001 acctgttttg gtatccaagg ctcctgtcgg ttcatccgct aggataatag aaggattgtt
    27061 taccaaggca cgcgcaatgg ctacacgttg cttttgacca ccagataatt ctgaaggtaa
    27121 atggtgacta cgttctgtca attcaacctt gtctaaatat tcctcagcca acttgcgacg
    27181 ttttgaagac gaaactcctg cgtaaatcaa gggcaattct acattttgca gagcattgag
    27241 cttcgataga agaaagaact gctgaaagac aaaaccgatt tgttggttac ggaccttagc
    27301 tagttgtttt tcaccaagcc cagccacttc ttgaccttca agataatatt ctccactggt
    27361 tggtgtatcc aacatgccaa tcgtattcat cagagtggac ttaccagacc cagatggtcc
    27421 catgatggct acaaattcac cctcattcac ttctagattg atatttttga gaacctgcag
    27481 ttcttggtca ccattacggt aacttctgaa gatatttttt agactaatta gttgcttcat
    27541 cagccttcac ctcttttcct tcttccaagg aagatgttgg attactgatg accttagcac
    27601 cgttcgttaa accagaagtg atttcttgat tttctgcgtc agcatttccc aatgaaacct
    27661 caactttttt agccttttgt tgttcatcca caatccagac ataattttta ctatcatcca
    27721 ttactagact gctaacagga acaagaatag ccttagtttt gcttttaacc tcaatgttga
    27781 cagaaaaacc ttgtttcaaa tcaccaacct cgcctgtcac atcaatagta taagggtatt
    27841 tagaacctgt attattcccg gctgctggac tagctgcttc accattgttt ttaggatagt
    27901 cagaaatata gcttaatttc ccagtccatt ttttatcagg atacacttta gaagtaaagc
    27961 ttacttcttg acctacagaa aggttggcta gattgtactc agacaattct cccttgactt
    28021 gtaaattttc attgctgaca atatgaacca taacttgact cgcccctgtt ggagatttag
    28081 aaacattgct attgacttcg actacagttc cctctagggt actgagaaca gttgttgcat
    28141 ccaattgact ttgagccttg cttaattgcg ctgcagcatc tgcacgcgca tcacgggcat
    28201 cacccaattg agcatcaata gaagcaacag aatttccagc cactggagtt gggctttgca
    28261 ccgttgcatc ttctcctcct actggcgctg gtaactgtgg agcctgagct gaagcggctt
    28321 catttcgtgc ttgattgagt tcattgatat gacgatctgc cttagctact gctcgactag
    28381 ctgaatcata ggccgcctgc gcttctgaac tactgtactt gactaaagcc tgcccttcgc
    28441 tgaccttatc gcccacagaa acaaggattt catctaaatc acccttacta gcatcaaaat
    28501 aaacatattg ttcatttttt gctgttactg tccctgacaa taaaacagag gatgccacgc
    28561 ttccttcctt ggcaacaaca agatgagtag gctcatcttt tagagcagtc tgagaaggtt
    28621 gtctaaaaag taaaatcccc ccggcaccca atacaactac actcgcagca ccgattgctg
    28681 catacagttg ccacttttta gctttaccat tctttttctt cataatgaaa ctccttttct
    28741 tttttacaat actttgctat tataccaaat ttccctccag caaacaatgc agttcagatg
    28801 gaaataatgg cagttcagga ttaaacaatc gttcggaatt ttgcttttct attgtactag
    28861 atatataata cactatcttg acttatttgg caagcttttt tgcaattttt tgtgcgtagc
    28921 agatttttgc aatcaaatca aaaaaagaat aaaatataac tatcaaaaaa gacgctctac
    28981 tatttaaaag attacaaagg agttttcaat gagagaatat gatatcattg ctatcggtgg
    29041 aggtagcgga ggaatcgcta ccatgaaccg tgctggtgaa catggagcca aagcagccgt
    29101 tattgaggaa aagaaattag gtggaacctg tgtcaacgtc ggttgtgttc ctaaaaaaat
    29161 catgtggtac ggggcgcaaa tcgctgagac tttccatcaa tttggagaag actacggctt
    29221 taagactact gatcttaact ttgactttgc aaccctacgt cgcaatcgtg aagcctacat
    29281 tgatcgcgct cgttcttctt atgatggtag ttttaaacgc aacggtgtag acttgattga
    29341 aggtcatgct gaatttgtag attctcatac tgtaagcgta aatggtgaac tgattcgtgc
    29401 taaacatatc gtgattgcta caggtgccca tccaagtatt cctaatattc ctggtgctga
    29461 gctaggtggc tcttctgatg atgtatttgc ctgggaagaa cttccagagt cagttgccat
    29521 tctaggcgct ggttatatcg ccgttgaatt agctggcgta ctccacactt ttggtgtcaa
    29581 gacagatctc tttgttcgcc gcgatcgtcc tttacgtggt tttgattcct acatcgttga
    29641 aggtttggtc aaggaaatgg aaagaacaaa cttaccactt cacactcaca aagtccctgt
    29701 caagttagaa aaaactactg acggcattac cattcatttc gaagatggta ctagtcacac
    29761 agctagccaa gttatctggg ctacaggccg ccgtccaaac gttaagggct tgcaacttga
    29821 aaaagctgga gtgactctga acgaacgtgg ctttatccaa gtggatgaat accaaaatac
    29881 tgttgttgag ggactctatg ctctaggtga tgtaacgggc gagaaagaac tgactccagt
    29941 tgcaatcaag gccggacgta ccctatctga acgtctcttt aacggaaaaa ctactgcaaa
    30001 aatggattac tcaactattc caactgttgt cttttcacac cctgctatcg gaactgttgg
    30061 tttgacagaa gagcaagcta ttaaagaata cggtcaagac caaatcaagg tttacaaatc
    30121 aagctttgca tctatgtact cttcttgcac tcgcaaccgt caagaatccc gtttcaaact
    30181 cataacagct ggttcagaag aaaaagttgt cggacttcat ggaattggct acggcgttga
    30241 tgaaatgatt cagggatttg ccgttgctat caaaatggga gcaaccaagg ctgactttga
    30301 tgcaactgtg gcaattcacc caactgcatc tgaagaattt gtaaccatgc gttaatcgaa
    30361 acaaaagaag cttatataaa tatgtctgct tcttttttaa tgattttcga atcaacaaaa
    30421 aaattatcca acttgactag tcacgaaaat cggctgttac agtttttgtt accttgtttt
    30481 taaaaaatgg ttgacatcga ctcctatatg agtataatag ttactataca ttagaaaaga
    30541 ggttaactat tttgaaaaaa gctcacgttt atgctatccc tgctattggg gctgctctca
    30601 ttgctgtttt ggcacaaatc agtcttccaa ttggacctgt tcccttcact ctgcaaaact
    30661 ttgcaatcgg cttgattgct actgtcttta gaccgagaga ggctgtactt tctgctggac
    30721 tctatcttct tctaggtgct atcggtcttc ctgtctttgc aggaggtgga gctggttttc
    30781 aggctttagt tggccctact gcaggctatc tttggtttta tctcgtttac tctggactta
    30841 cttcctctct aaccaacagc aagagtggtg ttgttaagat ttttcttgca aacctcttgg
    30901 gtgatgccct tgtctttgtc ggcgggattc tcagcttgca tttcctagct ggaatggcat
    30961 ttgaaaaagc tcttgttgtg ggggttcttc cctttatcat tccagacctt ggcaaacttc
    31021 tggctattag ttttattagc cgtcccctac ttcaacgcct taaaaatcag gcttacttta
    31081 ctaactaaaa aaggataccg agttatcatg actcaatatc ctttttttat tttgaaaact
    31141 tatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggctgc tcaaaacact
    31201 gttttgaggt tgtggatgaa actgacgaag tcagtaacca tacatacggc aaggcaaagc
    31261 tgatgcggtt tgaagagatt ttcgaagagt attagttgcc tttaaaggca tccaccatcg
    31321 tttgaaattc ttcatttgag agagtaatcc ctttgcccat tttagtatgg tctggactcc
    31381 aagcacgaat atcaaacttt gcagaggcac cattaaagct cacacggtta atttccttgg
    31441 tccaaccttt ttcgttttca gaaagagtca acaagtgctc ttcgatttca aatgtaaatt
    31501 ctgccatttt cttctccttt tttagtttca ttagtttatt cgtaaaatct tgtagatttt
    31561 aggaaaattt tatataatat tgatataaaa gaagggaggc caatatgaga cataaattcc
    31621 agcaagttct aaataaaata catgattttt taaatggata tgaccaacct gaccagactg
    31681 aaaccaactc ccttacagcc actattgaag aggctatcca gaaacaaacc gctgttcacc
    31741 ttatcttatc tgagacaagc tttacaggtg acatcatcaa atatgatcag caaggccagc
    31801 aaattatcgt gaaaaatttt tccaaaaatg tgagtcggat tatccgtata agcgatattc
    31861 aacgcctgcg atttgtcccc tcaactgtcc aaacagccca aaaaaataga tttaagaaag
    31921 agtgagatgt agttgcttca tcccactctt ttttcttagc gaatttgttc aaaatgtaaa
    31981 tgaactgcaa tatgatctcc ataaccactt ctttccaagt cacgttgtaa acgataggaa
    32041 atgtagtgtt ctgcaatggt aatgtaacct gcgcccaata aacgatgttc aaccatagat
    32101 tgaatcatac tgatagtcgc acgttccacc ttggcttctt gtaaatccaa aactaccttc
    32161 ttagtgactt gagcaagatt ttgacgcaaa tcatctgtca aaacataaac agtttgggct
    32221 gccttcaaga tggcttggta aatcttatct ggattaaatt cagcaatttc gccattacgt
    32281 ttgattactt gcataggttt ctcctttatt ctttgttttc tttgatttct gccagcattt
    32341 tttcttcttc tactgtcagt tgataatgtt caagtaaatc cggtctgcgc tcgtaggttt
    32401 tctttaaact ctcgtacaat cgccactgac gaatcttttc atggtggcca ctcatcaata
    32461 catctggcac gaccatgcct cgataatcat agggacgtgt gtactgagga tattctaaaa
    32521 gacctgaaga aaaactatca tcttggtggc tagactcctt gccaatcact tctggaatca
    32581 ggcgaactgt agcatcaatc atggtcatag ctgccaattc tccaccagtg aggacatagt
    32641 cgcctaggga aatctcatct gttaccaagg tcttaatgcg ctcatcataa ccctcatagt
    32701 gcccacagat aaagattagc tcttcctctt gagccaaatc ttcagcataa gcctgatcaa
    32761 actgctttcc agcaggatcg aggagaataa cgcgcggatt tttcttttca atagcatcaa
    32821 aggaatcgaa aataggttgt gctctgagca acatgccctg accgcctccg tagggctcat
    32881 catctacatg acgggccttt tcagcatttt ctcgaaaatt atgatactgg atatccaaga
    32941 gccctttttc tcgagccttt ccaacgattg agtgctccag tggagaaaac atctctggaa
    33001 agagggttaa aatatcaatc ttcatcgtct aacccttcta agatttccac atcgacccgt
    33061 ttatttggaa tatcaacatt gagaaccact ggtgggatat aaggtaaaag caaatcacgt
    33121 ttgccttttc gtttgaccac ccagacatca ttagcacctg gttgcaggat ttccttgatg
    33181 gttccaacca agctatcacc ctcatagact tccaaaccga taatctcgtg atagtaaaat
    33241 tcaccatcgt ctaggtcatt caaatcttcc tcagcgacct tgagactgta tcccttgtac
    33301 ttttcgatag tattgatatg gtacatatct ttgaatttaa taatgtcaaa gttcttctgt
    33361 ttacggtggc tagcgatggt cactgtttgg acaaactgat ctttttcatc aaacaaagcc
    33421 agctcagctc cttttttaaa ccgttcttct gcaaaatccg tcacagacaa gactcgcatc
    33481 tcaccctgta atccctgcgt attaacgatt ttcccaacat taaagtagtt catcttgtct
    33541 cctgtaatct ccttttttcc atcttattct gacaattctc gaataatagc cgcaattttt
    33601 tcctattctg accattgtaa ataatggtga ttccttccta aaatgagttt agtattggaa
    33661 gtccaatatt ctgattctct gtactctttt tctctataag tctgacaaaa aataaataca
    33721 gggacatgag attctatcga caaattctca aaatcttcct cagtaatctc tccagatatc
    33781 tgaaattctg gatcttgatt ttccaactct aagccttttt cttgcattaa ttcccagatt
    33841 tttttattcg tttcaggact aaatgttgct tgagttaagt tcttaaaata aagttcagga
    33901 ccacactcgt caatcagcct catctgctct tccatttctg gataagaatt ttctaaaaaa
    33961 tcagcaaaca tgacttttta gttgtcggtt caattgctac taaagtctga cgcttaattg
    34021 gtttctcgag taatttgcaa gctaaaattc cactccaact atgtgcacaa agtatatatt
    34081 cagaaattcc taattcttca agtacttcat aaaccgcatc tgcaagatta tctagatttt
    34141 ttccagcttg gtcatgaatc ggactcctac ctgtgttcgg aaaatcaatt gtcaaataac
    34201 caattgtagg aggaggtttt tcaagtataa gtgaaaaatt ttcataactt ggtagcaaac
    34261 ctgctccgtt tagacaaact agcactttct tttgcttttg ataagcaaca gagagactac
    34321 caatttctgt agatacttca aacctcttca taaagaaatc cactcattct atataatgaa
    34381 ttattaaaaa tccttatctt ttattttatc acgttccaag gattttctca agttggagga
    34441 aggggacaac atctctactt tcccttcaaa aatccttcca aatcatgttt atgttggtaa
    34501 ttaacggctg cggttttgtc tttctcaaag acagtcttgg taaggtcaat atgattaata
    34561 gctacgattg cgacggtgta gtaaatgata tcagccagtt ctctggcaag ttcctcgttc
    34621 gaatcctatc ccttcttttc gaccagagcg cctattcaaa acctcggcta cttctccgac
    34681 ttcctccact aacttcataa agagaccttc atcagtccga gactgctgtt aatgttcgag
    34741 taagtagtct tggaattgcc taaacgttca atcttttata gtatattgaa actagaatag
    34801 tacaccttta cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttgtcc
    34861 tgttattatt tcattttact atatcttcta ttccacacaa aaaagcgaga catccgtccc
    34921 gcccttctta tttttcgtca ataacgattc ttactttttt gtattcagtt gggacagagt
    34981 agacaatcgt tcttatcgca gaaatagtgc gacccttacg accgattaca cgacccacat
    35041 cgctttgatc aagattcaaa tgatattcca aaaattctgg tgtatcttca atcttgatag
    35101 ttaaggcatc tggttgtgaa attaagggtt tcacaatcgc aataatgaga ttttcaatcg
    35161 tatccatctg tcaacctact ttaaacttat tttgagaatt tagaatcgtg gaattttttc
    35221 aatacgcctt cttttgaaag gatgttacgt actgtgtctg aaggttgagc tccattagcc
    35281 aaccatgcaa gaacgcgatc ttctttcaaa gttacttggt tttcagcaac aagtgggttg
    35341 taagttccaa ctgtttcgat gaaacgtccg tcacgtggtg aacgtgaatc tgctacgttg
    35401 atacggtaga aaggtttttt cttagaaccc atacgagtca aacggatttt aactgccatt
    35461 tttaaagtct catttcttta attttttatt tcggtgaaat agctgagcta tttagcacat
    35521 gttctattat agcagatttc tggcatgtgt caagaaaaaa acttgacaga ctataaattt
    35581 cttaaagtat ttagaaattt gttagaatag gaaataaatg tttgaaagat gctatccgtg
    35641 aatactattt tagaaaaatt ttataaagaa caccaagtca aacccttcat atcgcctgaa
    35701 cgagagttgg atacttggct tctaagtccc aagcccgttc ccaagcgaaa tatggactta
    35761 ttagcagatg attcactagc aggagatatc attttactat ggagaatcca gtttggtact
    35821 tttaccactg aaacatgatt ttaaaaactc ccattcgaat atgattcaaa attcgcttag
    35881 aatcaatgtt ttcccacttt ttcaaaaaat aaattttcat ctaatttaaa taactttcaa
    35941 ttaagtgtga attttgctta aaatcattaa aaaacacccc atggtgtgaa ccatgaagtg
    36001 ttgtaaatgc tgtgttgtag ctagttctta gcgtttagag aactggctag ctttacgagc
    36061 tttcttaaga tctggtttcc aaaatacttt gagtacactt atggtattga tgcccctaaa
    36121 catctaaaaa ctctggtaga aaaagggtat gctcttgtcg aaacttcttt tgactcactt
    36181 gaccatctaa atactaccat gaaaaagaat atcctgaaga agaagggagt tactggactt
    36241 tctaaaatga aatcttgcga cctggatcaa gcccttcatg agcatttttc agaagaagaa
    36301 ttagctggtc actttcatgt ccttctatgg acttttttac aatggcattg ctatcacacc
    36361 caatacctat ctaagcgcct ggttcgtaaa ctttattgca gctcttcctc taaatttcct
    36421 aattgttgaa ccaattgccc gttttatact aagttctttt cagaaaccat ttactgggga
    36481 agaagttgaa gaagttgaag attttcaaga tgatgatgaa atcccaacta ttatctaagc
    36541 cagttctgta aactactaat atttgaaatc cacttccttt tagggtacaa tggttataaa
    36601 tgaatttttg agaggatcag aatgaaaaaa ctagcaaccc ttcttttact gtctactgta
    36661 gccctagctg ggtgtagcag cgtccaacgc agtctgcgtg gtgatgatta tgttgattcc
    36721 agtcttgctg ctgaagaaag ttccaaagta gctgcccaat ctgccaagga gttaaacgat
    36781 gctttaacaa acgaaaacgc caatttccca caactatcta aggaagttgc tgaagatgaa
    36841 gccgaagtga ttctccacac aagccaaggt gatattcgca ttaaactctt ccctaaactc
    36901 gctcctctag cggttgaaaa tttcctcact catgccaaag aaggctacta taacggtatt
    36961 accttccacc gtgtcatcga tggctttatg gtccaaactg gagatccaaa aggggacggt
    37021 acaggtggtc agtccatctg gcatgacaag gataagacta aagacaaagg aactggtttc
    37081 aagaacgaga ttactcctta tttgtataac atccgcggtg ctcttgctat ggctaatact
    37141 ggtcaaccaa acaccaatgg cagccagttc ttcatcaacc aaaactctac agatacctct
    37201 tctaaactcc ctacaagcaa gtatccacag aaaattatcg aagcctacaa agaaggtgga
    37261 aaccctagtc tagatggcaa acacccagtc tttggtcaag tgattggcgg tatggatgtt
    37321 gtggataaga ttgctaaagc cgaaaaagat gaaaaagaca agccaactac tgctatcaca
    37381 atcgacagca tcgaagtggt gaaagactac gattttaaat cttaaaaacc aaaaaaaata
    37441 cagtatccac attcggtact gtatttcttt tactctcatt cttaagttaa attattaaaa
    37501 tcccatattt ggtctatcca gccttcataa aagtctagct cgtggcagac cataaggata
    37561 gatcccctat attctttgag agcgcgtttg agctcatcct ttgcatccac atccaaatgg
    37621 ttggtcggct cgtccagcac taaaacgttg ttttcacgat tcatcaagag acagaaacga
    37681 accttggctt gctctccccc tgataatact tgaatctggc tttcaatatg tttggttgtc
    37741 aaaccacaac gggcaagggc tgcacggact tctgcttgat taagggcagg aaaggcattc
    37801 cagacagctt caagaggagt ttggcgatta ccgccttcta cttcctgttc aaaataacca
    37861 agttctaaat aatctccacg ctccacttcc ccagcgattg gcgagataat gcccaagaga
    37921 ctcttcaaga gagttgtttt tccaatacca ttagcaccaa taatcgcaac cttttgattg
    37981 cgttcgaagg taagatttaa aggcttagta agaggacggt cgtaaccaat ttgcaagttc
    38041 ttggcttgga agataaagcg ccctggtgta cgagctggtt tgaaatcaaa ggatggtttt
    38101 ggtttctcac tttggagttc gataatatcc atcttatcca atttcttttg acgagacata
    38161 gccatattac gagttgcaac acgggcttta ttacgagcca caaagtcctt gaggtctgca
    38221 atctctttct gctggcgttc gtaggctgcc tctagctgag atttcttcat agcataaact
    38281 tcttggaact ggtagtagtc accagagtaa cgcgtcagct gttgattttc cacatgatag
    38341 acaatattaa taacgtcatt gaggaatgga atatcgtgcg aaatgagaac aaaggcattc
    38401 tcatagtttt ggagatagcg cttgagccaa tcaatatgct cagcatccaa gtagttggtc
    38461 ggctcgtcca acagcaagat atcaggcttt tcaaggagaa gttttgccaa aagcaccttg
    38521 gttctttgcc cacctgacaa agaagttaca tccgtatcca tgccaaagtc cataacacca
    38581 agagcacgcg ctacttcgtc aatcttagca tccaaggtat agaaatcacg actctccaga
    38641 cggtcttgaa gttctcctac ttcttccatg agagcatcaa catccgcgcc gtcttcagcc
    38701 attttcatat agaggtcatt gatacgagct tcagctttga aaagctcatc aaaagccgta
    38761 cggagaacat cacgcaccga ctgtctttca gcaaggacag agtgctgatc caagtaacca
    38821 gccgtcacat atttggacca ctcaaccttt ccttcatctg gcagcatttt accagtcacg
    38881 atactcataa aggttgattt tccttcacca ttggcaccga ccaggccgat atgttctccc
    38941 ttgaggagac ggaaggacac atcttcaaaa attgcacggt caccaaaacc gtgactcaga
    39001 tttttaactt ctaaaatact cattttaatt ccttatcttg tttttatgta atcgtttata
    39061 aaggagccaa gccagatagc cacccaaagt gttggtccac aaatcatcaa tctcaaagac
    39121 gcgattgaaa tcaaagaaaa agtctaagat taattgcgta cactcgattc caagactcac
    39181 aagaaaacta aaaagaagga ccttttttgt tttccgcaaa tttggaaata gataaaggag
    39241 ttggaaaatc agaggaaaaa acaagaagac attgaggata ttttgtaaaa aaatccaaca
    39301 taattgtcca atgtcactca cttcgcccag tttccagaga gaattgaaag gagtcaaaag
    39361 aaaaaccagg cgtccaagat gctgaatacc tggagttccc actcccacgg tagattgttc
    39421 ttgaggagta aagcaaaaac agacaatgca aatgctatag aaaatgactc cccagaccaa
    39481 aatatgatta taagtcttct tcatcattaa ggatttaccg ctgcgactgc cttctggcgg
    39541 tcacgtttca ttgtgttaga gcgcaattgt ccacaagctg cgtcaatatc tgtaccatgc
    39601 tcttgacgaa ccacacagtt gacccctttt ttcttaagcg tatcatagaa agccaacacg
    39661 cgctctttgg gactacggct atattggtca tgctcactaa ctgggttata aggaatcaag
    39721 tttacataag acaatttctt gatgttcttg agcaattcag tcaattccaa ggcttgttct
    39781 acaccgtcgt tgacttcatt aagcatgata tattcaaagg ttacaccacg gtttgttgtc
    39841 tcaatgtagt attcaatagc agcaaagagt ttttcaatcg gaaaggcacg gttaatcttc
    39901 atgatacttg aacgaagttc attgttaggt gcgtgaagag acacggcaag attgacctga
    39961 accccttcat cagcaaagtc acgaatttta tgagccaaac ctgaggttga aaccgtgatg
    40021 tgacgagcac cgatagccat tcctttatca tcattgatag tacgaaagaa attcaagaca
    40081 ttgttgtaat tatcaaaggg ctcaccgatt cccatgacaa cgatatggct gatgcgttca
    40141 tcctgaccac gctcatcaaa gtatttctga accagcatga tttgcgctac gatttcaccg
    40201 ttattgaggt cacgttgctt cttaatcaaa ccagaggcac agaaggtaca accgatatta
    40261 cagccgacct gagtggtcac acagacagat aaaccatagt gttgacgcat gagtacagtc
    40321 tcaattaaca taccgtcggg caattcaaag agatatttga ctgtaccatc agcagactct
    40381 tgcacaatac gttgtttcaa gggattgacc acaaactggt cattgagctt agcaatcaaa
    40441 tccttggaaa ggttggtcat ttcttcaaat gactgcacac gtttacggta gagccattcc
    40501 cagatttgat ctgcacggaa tttcttttct ccctgctcca atacccattc ctgcatggtt
    40561 tgatgtacca aactatgaat tgagggtttc atttcttctc cttattctct actcacttct
    40621 gacgaatgac aaaatgacgt tgtcccttgt cctctttctg agaatgctgg tctttctgac
    40681 gacgtctatt tttcttatct gcattcgact ttcgtttagt ttgagtcggt ttctttcctt
    40741 ttctagaagg tgtttcttct tccgtcttac gcattttctt gtcaaatgat gctcgcttag
    40801 gggcttcatt ttctaagaca aaataggcac aaccataact acaatactct aaaaggtagt
    40861 cttgtaaacg actgattttt tcaagttttt cttctgttcg gtcatccttg taaaaacctc
    40921 gtaggcgaag ctgttcgttg ctccagtccc ccacgatata atcaaacttg gttaagactt
    40981 ctgaaaaacg ctgattaaaa gtcgtcacat caaaggcatc cttgatattt tcaaccaagg
    41041 aaaaagctat cccttccgtt tcgaccttgt ccccgtgtaa atggaactcc ggaccaggaa
    41101 acttgttata gttgtataat tcaggtgcaa tttcttttcg catagatatc ctttttccac
    41161 gattacttaa tactttattc taccataatt tctagcagtt agcacgtttc tcataaaaat
    41221 gaaaaaagtc tgacgatttt gtcagaccag aatcttataa cctaaaaaga gaagaacaat
    41281 tcttccctcc aactatcatt atttagcagc tgcgtacaat tcatctactt tattccagtt
    41341 gattactgaa aagaaagctt tgatgtagtc aggacgcacg ttgcggtatt tcacgtagta
    41401 agcatgttcc caaacgtcca agcccaagat tggtttttta ccttctgaga ttggtgtgtc
    41461 ttggtttgct gttgaagtca cttcaagttt cccttctttg ttgacaacca accatgccca
    41521 acctgaacca aaacgagttg ttgctgctgc agtgaaggct gcttggaatt cttcaaatga
    41581 accaaatgtt gcatcgattg ctgctgccag ttctgctgaa ggagctgttt tctcgggagt
    41641 catcaattcc cagaaaagag cgtggttcaa gtgtccgcca ccattgttga taagtgcttg
    41701 acggatatca gctgggatag attctacatc agcaagcaag gcttcaaggt cttcaccgat
    41761 ttcagggtgt ttttctaaag ctgcattggc attgttgaca taagtttgat ggtgtttgtc
    41821 atggtgtaaa tgcattgttt ccgcatcgat gtatggttcc aaagcgtcgt atgcatatgg
    41881 aagttctggt aagataatag ccatctgtaa tacctctttt tctttctata tgaaaatgat
    41941 aacgcaaaca ttcacttttt tcaagttttt tgcttataga taaggaaatc actgacatac
    42001 tttctaataa aataagcaaa tcagcaagaa acccacgaca agataatcct gacgcgggtt
    42061 gtagtttcaa caaatgtcaa ttgacctgac tagcaatctg taagagtgcc ttttcaaaaa
    42121 ggaaaccttt ttcataaaga cctgtcttaa tctgatagtc tgtctcaatc aaataggaaa
    42181 tagcttgctt cagaaagctc aaagaaagtc ctctcgaatc tcttaatgca aacttgattt
    42241 gataaggatt tgggttacgt cccagataac tacctaaact acttgcaatc tgcgattctg
    42301 tttggccaga ctccgccaaa atcttcacct gagtaaaagt ccgaaattgt cccagcatga
    42361 ctgcaatcag tttgatttca tcttcccctt gcaaggtcaa gtctctcacc aaatcgcgcg
    42421 cctgatccat ctttttagtc agaataaact gagttaaatc aaaaatattg tcctgcaagg
    42481 tcttgggaat tgcgttaaca atatcctctt cctcgataac agaatccgcc ttataggact
    42541 gtaaaaagag aagatttttc tggatttcgc taaattgaaa ccccgacttg atgaggagat
    42601 tttcaaaaga atgattggta aactgcagac cttgtttctg actccacttt tggaaatact
    42661 ggcgcaattc ttgttctttt acttctactg catcgaagac cttggcatca cgcttaagta
    42721 atttgactaa ccgtcttttg ctatccagct ttccttctgc aaagattatc aacttggttg
    42781 ttggagaagg attgtcaagg tattcctcaa atgacttaag ctcatcatct gtcaaaaagc
    42841 gtttcttagc agtcgtgata tccataaaat aatctaatat cactattttc tcatccgcaa
    42901 agaaaggaag gctgaccaac tccagttcca catccttgta aactacttct ttcatatcaa
    42961 agtaggcaaa gttgaggtca gcagaatcat acccaatctg tttcaacatt tgactcttca
    43021 tcacttcaaa ctgaccctga tctgtccctg taaataggct caggctcggt aaatttgata
    43081 aagtcaactt ctgactttct tcaatggcta gcatcgactc tcctttcttc agatttttcg
    43141 atttaattta gtcaatatag cgcaatttcc cacggaaatc ttctaagctc tcgtagcctt
    43201 tttccaccat gattgctttc agttcattgg taatgcggtc aaaagcactg acgccttctt
    43261 tgtgaagggt cgttcccacc tgcaccatac ttgctccaca gaggatgtgt tcaaaggcat
    43321 ctcgaccagt cagaacgcca cctgttccga taatttggat ttgaggattt aaacgttgat
    43381 aaaaggcgtg aacattggct agagcagtcg gtttgatgta ttctccacca attccaccaa
    43441 aaccattctt aggccgaata acgacagatt cgtcttctat atagaggccg tttccgatag
    43501 agttaacgca gttgacaaac ttgagcggat atttgttgaa aatagctgcc gcttggtcaa
    43561 agtgaacaat atcaaaataa ggtggcaatt taattccaag aggtttggtg aagtaagcaa
    43621 acacttctgc caaaatccgg tctgttgtct caaaatcata ggcaatctga ggtttacctg
    43681 gaacatttgg acaggaaaga tttagctcag tcagaccacg aaaatcactc tcttggactt
    43741 ttttcaaaat agtatgggtt tcctctggag acatgccgac cagagataag aagaaagttc
    43801 ggttcgactc tttttcctgc aaatctaaaa gataatccaa ataatagtct aagccattat
    43861 ttggcaagcc catagagttg atggaaccaa gtggaacatc ttggtagcgt ggctcaggat
    43921 tcccctgacg gaagtccaag gtcgctgtct tagtaacaaa ggttcctgcc gctgagtttt
    43981 tgacctcttc taactcctct atcgtcatac aagccacacc tgctgcattc atcaagcaat
    44041 tgtcaaactc aaaaccagca atttgtgttt tcgttgatac catgattcta atcctccaga
    44101 tttcttttat tgctaatatt ataccataat tttaattcta ggtttactag attctgtggt
    44161 tctatctatt tattcggaaa agaaagtcta gtacagaagt catgctatgg aaacagctag
    44221 tgtattggaa gtttgaacaa ggcttgggta acagactttt gaatgaagtc caagcaacaa
    44281 ggagaaatct caaccatgag tccattccat gactctgttg ctctagaaaa ccttgcaata
    44341 gtcaagtgat aacgaataaa actttggatt gaaatatccc catgattatc tattacgagg
    44401 agaaatctca acctttatca tttttagaga aatatagtaa aatgaaacaa gaacaggaga
    44461 aatcgatcag gacagtcaaa tcgatttcta acaatgtttt agaagttgag gtgtactatt
    44521 ctagtttcaa tctactatac atg
//
LOCUS       DBERXF010000014        43402 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.14, whole genome shotgun sequence.
ACCESSION   DBERXF010000014 DBERXF010000000
VERSION     DBERXF010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 43402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43402
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.14"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            464..838
                     /gene="dhaM"
                     /locus_tag="ACL8JK_000880"
     CDS             464..838
                     /gene="dhaM"
                     /locus_tag="ACL8JK_000880"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002960428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HGS1785788.1"
                     /translation="MESIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGGIG
                     TSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNAAA
                     LLQAGAELSVIQTQLAELEINK"
     gene            1296..2009
                     /locus_tag="ACL8JK_000881"
     CDS             1296..2009
                     /locus_tag="ACL8JK_000881"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGS1785789.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2043..2645
                     /locus_tag="ACL8JK_000882"
     CDS             2043..2645
                     /locus_tag="ACL8JK_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785790.1"
                     /translation="MTIEEYNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRLFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFEIGSKMLNDLKSNYKK"
     gene            2783..3436
                     /locus_tag="ACL8JK_000883"
     CDS             2783..3436
                     /locus_tag="ACL8JK_000883"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGS1785791.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGTIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3446..3910
                     /locus_tag="ACL8JK_000884"
     CDS             3446..3910
                     /locus_tag="ACL8JK_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGS1785792.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAVREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLGDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            3923..5191
                     /locus_tag="ACL8JK_000885"
     CDS             3923..5191
                     /locus_tag="ACL8JK_000885"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGS1785793.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5205..5465
                     /locus_tag="ACL8JK_000886"
     CDS             5205..5465
                     /locus_tag="ACL8JK_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785794.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5476..6837
                     /gene="pdrM"
                     /locus_tag="ACL8JK_000887"
     CDS             5476..6837
                     /gene="pdrM"
                     /locus_tag="ACL8JK_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HGS1785795.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            6991..7959
                     /locus_tag="ACL8JK_000888"
     CDS             6991..7959
                     /locus_tag="ACL8JK_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HGS1785796.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            7975..8967
                     /locus_tag="ACL8JK_000889"
     CDS             7975..8967
                     /locus_tag="ACL8JK_000889"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HGS1785797.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNSVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9185..10228
                     /locus_tag="ACL8JK_000890"
     CDS             9185..10228
                     /locus_tag="ACL8JK_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HGS1785798.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     RVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPCINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10274..11977
                     /gene="lpdA"
                     /locus_tag="ACL8JK_000891"
     CDS             10274..11977
                     /gene="lpdA"
                     /locus_tag="ACL8JK_000891"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGS1785799.1"
                     /translation="MALEVIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKV
                     SMELEAEEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTS
                     NDDGKSDDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTY
                     LHNAEIIENISHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTV
                     HKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNE
                     VPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGM
                     TILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCI
                     KVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIY
                     TLPEVAAVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGV
                     HIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKK
                     K"
     gene            12041..13030
                     /locus_tag="ACL8JK_000892"
     CDS             12041..13030
                     /locus_tag="ACL8JK_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGS1785800.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFVGISREEIAEAVVG"
     gene            complement(13103..14173)
                     /gene="xerS"
                     /locus_tag="ACL8JK_000893"
     CDS             complement(13103..14173)
                     /gene="xerS"
                     /locus_tag="ACL8JK_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGS1785801.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETAGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(14757..16307)
                     /locus_tag="ACL8JK_000894"
     CDS             complement(14757..16307)
                     /locus_tag="ACL8JK_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HGS1785802.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16323..17102)
                     /locus_tag="ACL8JK_000895"
     CDS             complement(16323..17102)
                     /locus_tag="ACL8JK_000895"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGS1785803.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17089..17940)
                     /gene="ylqF"
                     /locus_tag="ACL8JK_000896"
     CDS             complement(17089..17940)
                     /gene="ylqF"
                     /locus_tag="ACL8JK_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGS1785804.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            18022..18219
                     /locus_tag="ACL8JK_000897"
     CDS             18022..18219
                     /locus_tag="ACL8JK_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785805.1"
                     /translation="MMSKQFLFYDIEIYFILYHAFFILSDDSLLPYLLPYLLPYLLPY
                     IEKSHQMMTFQREQKTVPVIL"
     gene            complement(18183..18359)
                     /locus_tag="ACL8JK_000898"
     CDS             complement(18183..18359)
                     /locus_tag="ACL8JK_000898"
                     /inference="COORDINATES: protein motif:HMM:NF012948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGS1785806.1"
                     /translation="MQAGIPTDNEVSYDLIYQQETLPATGSSTSELTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(18411..24425)
                     /gene="iga"
                     /locus_tag="ACL8JK_000899"
     CDS             complement(18411..24425)
                     /gene="iga"
                     /locus_tag="ACL8JK_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HGS1785807.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAAMGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSESEVSNQKSSVATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSKNTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEPSNGN
                     STEDVSTESNTSNSNGNEEIKQENELDPDKKVEEPEKTLELRNVSDLELYSLSNGTYK
                     QHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKVEKLQQEI
                     ESRYKDNFTFYLAKKGTEETTNFTSFSNLVKAINQNPSGTYHLAASLNANEVELGPDE
                     RSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEKLSLKNVAISGKDDIGSL
                     ANEAQNNTKIKQVHVDGVLAGERGIGGLLAKAEQSSITESSFKGRIINTYETTAAYNI
                     GGMVGHLTGDKALLTKSKATVAISSNTNTSDQTVGGLAGLVDRDAQIQDSYAEGDINN
                     VKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGNAITGYHYNEMKVKDTFS
                     SKANRVYNVTLVKDEVVSKESFEERGTMLDASQIASKKAEINPLILPTVEPLSTSGKK
                     DSDFSKVAYYQAKRNLTYKNIEKLLPFYNKATIVKYGNLVNENSLLYQKELLSAVMMK
                     DNQVITDIVSNKQTANKLLLHYKDDLSEKLDLKYQNDFAKLAEYSLGNTGLLYTPNQF
                     LYDQTSIIKQVLPDLQKVDYHSEAIRKTLGISPNVKQTELYLEDQFAKTKQQLEDSLK
                     KLLSADAGLASANPVTEGYLVDKIKRNKEALLLGLTYLERWYNFSYGQVNVKDLVLYH
                     LDFFGKGNASPLDTLIELGKSGFNNLLAKNNVDTYGISLASQHGTTDLFSTLEHYRKV
                     FLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYSIGVYDRITSATWKYRNM
                     VLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALNDFVEENARETAKRQRDH
                     YDYWYRILDDNAREKLYRNILLYDAYKFGDDNTVGKATEVADFDNPNPAMQHFFGPVG
                     NKVGHNQHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRSGLGP
                     EFFAKGLLQAPDHPDDATITINSILKHSKSDSTESRRLQVLDPTTRFNNADDLRQYVH
                     NMFDVVYMLEYLEGNSILKLDTNQKQQLLRKVTNEYHPDPDGNKVYATNVVRNLTVEE
                     VERLRSFNDLIDNNILSSREYASGKYERNGYFTIKLFAPIYAALSNDIGTPGDLMGRR
                     IAYELLAAKGFKDGMVPYISNQYEEEAKQKGKTINLYGKTRGLVTDDLVLEKVFNNQY
                     HTWSEFKKAMYQERQDQFDRLNKVTFNDTTQPWQTFAKKTTSSVDELQKLMDVAVRKD
                     AEHNYYHWNNYNPDIDSEVHKLKRAIFKAYLDQTNDFRSSIFENKK"
     gene            complement(24634..25812)
                     /locus_tag="ACL8JK_000900"
     CDS             complement(24634..25812)
                     /locus_tag="ACL8JK_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785808.1"
                     /translation="MTLPVRKSLHNAVLQASEADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNVIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(25982..29632)
                     /gene="addA"
                     /locus_tag="ACL8JK_000901"
     CDS             complement(25982..29632)
                     /gene="addA"
                     /locus_tag="ACL8JK_000901"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGS1785809.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVELKQHLSRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIDSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADTYNEERKTQ
                     FAKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEKNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(29629..32904)
                     /gene="rexB"
                     /locus_tag="ACL8JK_000902"
     CDS             complement(29629..32904)
                     /gene="rexB"
                     /locus_tag="ACL8JK_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HGS1785810.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKVSRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQTEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKRLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKNLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLKKLDLADSKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(33104..33259)
                     /locus_tag="ACL8JK_000903"
                     /pseudo
     CDS             complement(33104..33259)
                     /locus_tag="ACL8JK_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            33357..33740
                     /locus_tag="ACL8JK_000904"
     CDS             33357..33740
                     /locus_tag="ACL8JK_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS1785811.1"
                     /translation="MFVSYFNLLFSIDYINCLSETTDKNWHKSDRIFVTNTGKPVHSS
                     ILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSENKIPLKTITDRVGHSDSEVTTS
                     IYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(33878..35182)
                     /gene="eno"
                     /locus_tag="ACL8JK_000905"
     CDS             complement(33878..35182)
                     /gene="eno"
                     /locus_tag="ACL8JK_000905"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HGS1785812.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            35346..35792
                     /locus_tag="ACL8JK_000906"
     CDS             35346..35792
                     /locus_tag="ACL8JK_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGS1785813.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(35789..36888)
                     /locus_tag="ACL8JK_000907"
                     /pseudo
     CDS             complement(35789..36888)
                     /locus_tag="ACL8JK_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(36897..37226)
                     /locus_tag="ACL8JK_000908"
     CDS             complement(36897..37226)
                     /locus_tag="ACL8JK_000908"
                     /inference="COORDINATES: protein motif:HMM:NF019887.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HGS1785814.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVEQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCAKEVLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(37171..37545)
                     /locus_tag="ACL8JK_000909"
     CDS             complement(37171..37545)
                     /locus_tag="ACL8JK_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase"
                     /protein_id="HGS1785815.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVCGVW
                     WIPIVGEISKIPWYCLFHCQPA"
     gene            complement(37604..39037)
                     /gene="glgA"
                     /locus_tag="ACL8JK_000910"
     CDS             complement(37604..39037)
                     /gene="glgA"
                     /locus_tag="ACL8JK_000910"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HGS1785816.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(39034..40173)
                     /gene="glgD"
                     /locus_tag="ACL8JK_000911"
     CDS             complement(39034..40173)
                     /gene="glgD"
                     /locus_tag="ACL8JK_000911"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HGS1785817.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     FRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEHGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(40163..41305)
                     /locus_tag="ACL8JK_000912"
     CDS             complement(40163..41305)
                     /locus_tag="ACL8JK_000912"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HGS1785818.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(41295..43223)
                     /gene="glgB"
                     /locus_tag="ACL8JK_000913"
     CDS             complement(41295..43223)
                     /gene="glgB"
                     /locus_tag="ACL8JK_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HGS1785819.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFASLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT        12527 a         8726 c         8592 g        13557 t
ORIGIN      
        1 gaagtagata gtctcttggc tttattaaag gagagtaagt aaaggtagca gcattttcta
       61 actcctaaaa acaggatagg agaacgggaa aacgaaaaat gagagcagaa tgtgagttct
      121 agttctcatt tttttcatga aaatgtgcaa aatatagtag attgaaacta gaatagtata
      181 cctctacttc taaaacattg ttagaaatcg atttgattgt cctgttctta tttcatttta
      241 ctatatctta acagatagtg taaataaaga taaactattt actggctaat taatcagtta
      301 aacactagtt aaggagtaat gatgaaaaaa agaacaatac tattattgat ggccagtctg
      361 ttagctcttg tcttaggagc atgtggtttc ttggacatat tgttcctgga tcattctcat
      421 caggattact atttactgct attttagaaa ctggggtggt ttgatggaaa gtattggtct
      481 tgttatcgtt tcacattcca aacatattgc agaaggtgtt gttgaactaa ttagtaaagt
      541 agctaaagat gttccgatta cttatgtagg aggaaccgag ggcggaggaa ttggaacgag
      601 ttttgatcaa gtagataggg ttgtttccga aaatccagca gatactttac ttgccttttt
      661 tgacctaggt tctgctaaaa tgaacttaaa aatggtgact gatttcagtg ataaaagtat
      721 catcatcaac agggttccaa ttgtagaagg tgcctataat gcagctgctc ttcttcaggc
      781 tggtgcagaa ctgtcagtta ttcaaacaca gttagcggag cttgaaatca ataaataagg
      841 aattttacta taactctttt tataggtaag ctattgatta tctcaactat aaaatgttaa
      901 gtaaatgatt tcaaaatcag aaagggattg ctttatgcag ttccttttta ttttaacagg
      961 agtgaaacta tagtgtttct aaattgtgaa tcaatcaaaa ctgattgtga tggggctatt
     1021 ctagctttag aatccttcaa aaattaaaat ttaaggcaat caattacttg gaagagtatg
     1081 aaagcattta gtttatagga attctaggtc tagaattaca tatgtattta tgaagacggg
     1141 gtgttcgata gttagtattg ttctattctg aaagatttga gctgtcagtt gtatagaaag
     1201 tgttcgaatt tttttaagtg attaaattag ttaattgtat gaggtgcttt atgatataat
     1261 gttcttaatg aattttcaga aaggaaaacc tcaaattgtt ctacaaattt ctactcttcg
     1321 acctcgacca cactcttctt gattttgatg ctgctgagga tgtggctttg acccaacttc
     1381 taaaagaaga aggagttgcg gatattcagg cttataaaga ttattacgtt cctatgaaca
     1441 aggctctctg gaaagacttg gagctgaaga aaatcagtaa acaagagttg gttaacacgc
     1501 gcttttctcg tttattttct cattttggac aggaaaaaga cggtagtttt cttgcccagc
     1561 gttaccaatt ttatctcgct cagcagggac aaacactatc gggcgctcat gatctcttgg
     1621 acagcctcat tgagcgtgat tatgacttgt atgctgcgac aaatggcatt actgccattc
     1681 agacaggacg tttggctcaa tctggtctag taccttattt caatcaagtc tttatctcag
     1741 aacagttgca aactcaaaag ccggatgctc tcttttatga aaagattggc cagcaaattg
     1801 ctggatttag taaagaaaag acgctgatga ttggagattc tctaaccgcc gacattcaag
     1861 gtggcaataa tgcggggatt gacactatct ggtataatcc tcatcacctc gaaaatcaca
     1921 cacaagccca gccgacttac gaagtctatt cttaccaaga cttgctggat tgtttagata
     1981 aaaatattct tgaaaagatc acattttaaa ggagacgagc taatgactac aaaaaagcta
     2041 atattactat tgaagagtac aatgaagctg ttaattatga atttacatct gacacttgtc
     2101 aattagcaaa tagtatttat caatctcttt ttaagttttt tgataagaaa aatttctctg
     2161 gcgatttaat ttttacttgg aaatctccat cattagtcaa agaaggggat tatattggga
     2221 gaagggattc acaagtagat aatcttagag taataggaaa tatatttccg aattatctta
     2281 ctaatcgaaa atatagcctc aatatgaatc gtaatggctg tatgggagat tttcctcatg
     2341 acttttttga tatataccta gatcatgtag caaaatatgc ctacgaacaa aaagttaata
     2401 atattaaaga gtattatcct ttaaaaagag cgattttaca ccaagagaat gcattgtatt
     2461 ttcgattgtt ttctaatttt gacgactttt tagaaaaaaa ttatttaaag actatatggc
     2521 aagtttctaa agaaactcct ttttctgaaa tggattttaa tatgtttaaa aatatttcag
     2581 aaaagataat cttcgaaata ggtagtaaaa tgcttaatga tttaaaaagt aattataaaa
     2641 aatagccagt ctttataaac tgtattcacg tattcaaatc gtatatatag tcgatttatt
     2701 aaatctttag ataaactgta aaaagtggtt tccatagcca ctttttgcta taatagaggc
     2761 agtaaaaatg aaggagttgg ctatggaaca ctcgtcttgg cacgctttga ttaaggcgca
     2821 attacctgag ggttatttcg ggaaaatcaa tcagtttatg gagcaggtct attctcaggg
     2881 gactatttat ccacccaagg aaaaggtttt tcaggctctc ttgacaacac tgcttgaaga
     2941 agttaaggtg gtaattctag ggcaagaccc ctaccacgga ccaggtcaag cgcagggctt
     3001 gagtttttct gtacctgact ctatcccagc tccaccatcc ttgcaaaata tcttgaaaga
     3061 attgtcagat gatatcggag ttaagaaatc tcatgatttg acagcttggg ctgagcaagg
     3121 agtcttgctt cttaatgctt gtttgactgt tcctgctgga caggccaatg gtcatgctgg
     3181 tcaaatctgg gagcctttta ctgatgctgt gattcaggtg gtcaatcatc tagatagacc
     3241 agtcgttttt gtactctggg gagcttatgc acgtaagaag aaggcattag ttaccaatcc
     3301 tcatcacttg attatcgaat cagcccatcc aagtcctttg tcggtttata gaggattttg
     3361 gggttccaag cccttttcca aggccaatgc attcttaaaa gagacaggac aagagccaat
     3421 cgattggctt agataaggag aaaatatgcc tcagttagcg acgatttgct acattgataa
     3481 tgggaaagaa ctgctcatgc tccatcgtaa taagaaaccc aatgatgtcc atgaagggaa
     3541 atggattggt gtgggtggta agctagagag aggagaaacg ccccaggaat gcgcggtgcg
     3601 tgaaatcctt gaagaaacag ggctcaaagc caagccagtt ctaaaaggtg tcatcacttt
     3661 tcctgaattt acaccagatt tagactggta cacctatgtt tttaaggtga cggagtttga
     3721 gggcgacttg attgactgca atgaggggac gctagaatgg gttccctatg atgaggtttt
     3781 gagcaagccg acttgggaag gtgaccacac ctttgttgag tggcttttag gggataaacc
     3841 cttcttttca gccaagtttg tttatgatgg ggataaattg ttggataccc aagttgattt
     3901 ctatgaataa aggagaaagc agatgctact aatcaaaaat ggtcgtgtaa tggatcctaa
     3961 gtctggtttg gatcaagttt gtgatgtctt agttcaagat gggaaaatta tcaaaattgc
     4021 gcctgagatc acggaagaag gagcagaaac gattgatgct actggtcttg tggttgctcc
     4081 tggtttggtc gatattcatg tgcatttccg tgaacctggt caaacacata aagaagacat
     4141 tcatactggt gccctggcag ccgctgcagg tggttttact actgtcgtca tgatggctaa
     4201 taccagtcca accatttcag acgtggagac tttgcaagca gttctccagt cagctgccaa
     4261 agagaagatt aatgtcaaga cagttgcgac cattactaaa aactttaatg gtaaaaactt
     4321 gactgacttt aaggcgctct tagaagctgg tgcggttggt ttctctgatg acggtattcc
     4381 gcttgagagc agtaagattg tcaaggaagc catggaggaa gccaaaaaac tcaatacctt
     4441 tatcagcctt catgaggaag atccaggttt gaacggtgtt cttggcttta atgaaaatat
     4501 tgctagagaa catttccata tctgcggtgc tactggggtg gctgagtacg ctatgatggc
     4561 gcgtgatgtc atgattgcct atgcaactaa agcccatgtt cacatccagc atttgtctaa
     4621 ggaagaaagt gttaaagtag tggagtttgc tcaggggtta ggtgcagaag tcacagcaga
     4681 agtagcgcca cagcatttct ctaagacaga agcacttctt ttaacacaag gtagcaatgc
     4741 taagatgaat ccaccgcttc gtttggaatc agaccgtcgt gccgttatcg aaggtctcaa
     4801 atcaggtgtc atcacagtta ttgcgactga ccacgcgcct catcatgtag atgaaaaaaa
     4861 tgttgaggat attaccaaag cgccatctgg tatgactggc ttagaaacat ccctgtctct
     4921 cggcttgacc tatttagtag aagctggtga gttgagcttg atggaattac ttgaaaaaat
     4981 gacatacaac ccagccaagc tttacaactt tgaagcaggt tacttggctg agaatggtcc
     5041 agcagatatc actatttttg atgccaaggc tgaccgcctt gtggactccc attttgcttc
     5101 caaagcagct aattcaccat tcatcggtga aaccttaaaa gggcaggtta aatataccat
     5161 ctgtaaggga caaatcgtct atcaagcttg ataggagtta gaatatgaat tattttcgaa
     5221 aacgtaggga gagacaagcg aaatctaata gtggaattta ctgtcccgca gctaatcgtt
     5281 ccaaaattca atatgaaact aaagaaaaag ctgaccatgc ggttcaatat gataacggag
     5341 gtttagttag aagctattat tgtcgtacat gtgcgtgttg gcatactact tcaaaatcta
     5401 ataaacctcc gctaagtttg aaaaactatg gtctgaaact ctttggttta gataaatcag
     5461 aatagaaaga gaagtatgta taagacaaag tgtttacgag agaagttagt attattttta
     5521 aaaattttct tcccaatcct gatctaccaa tttgccaatt attctgcctc ttttgttgat
     5581 actgcaatga caggtcaata caacactatg gacttggctg gtgtatctat ggcaaccagt
     5641 atctggaatc ctttctttac atttctaaca gggattgtgt cagccttggt gcctatcatt
     5701 ggtcaccatc ttggtcgagg caaaaaggaa gaagttgcgt ctgattttta ccaatttatt
     5761 tatttggcct tgggcctatc tgtggtcttg ctggggatgg tacttttctt ggcaccaaca
     5821 atcttgaatc atattgggtt agaagcagca gtagcggcag tagcggttcg ctatctttgg
     5881 tttttatcta tcgggattat ccccttgttg ctctttagcg tcattcgttc cttgctggat
     5941 tcgctgggct tgaccaaact gtccatgtac ctcatgcttt tgttactccc tctcaatagc
     6001 ggatttaact atctcttgat ttacggtgcc tttggtgttc cagaactggg aggggctggt
     6061 gctggtttag gaacatcctt ggcctactgg gtcttgcttg ggatttctgt tctggtttta
     6121 tttaaacagg agaagctcaa agccttacac cttgagaaac gaattccact taatatggat
     6181 aacattaagg aaggagttcg tttaggtctg cctattgggg gaactgtttt cgcggaagtg
     6241 gctatctttt cagtggttgg cttgattatg gctaagtttt cgtccttgat tatagctagt
     6301 caccagtcag ctatgaactt ttcaagtctt atgtacgcct ttcctatgag tatctcatcg
     6361 gctatggcta ttgtcgtttc ctatgaagtg ggagccaagc gatttgatga tgcgaaaacc
     6421 tatattggtc taggaagatg gactgccctc atttttgcgg ccttcacctt aaccttcctt
     6481 tacattttta ggggaaatgt ggccagtctt tatggtaacg acccaaaatt tatcgatttg
     6541 acagtgcgtt ttttaactta tagtcttttc ttccagttag cagatacctt tgcggcgccg
     6601 cttcagggaa ttttgcgggg gtataaggat acagttattc ctttttacct tggtttgctt
     6661 ggttattggg gcgtagcaat ccctgtggct acgctatttg attctctaac agattttgga
     6721 gcttattctt actggatcgg cttgattatt agtttgattg tgagtggggc gctctaccgt
     6781 tggcgtttaa ctgtgattat gaagagattt gaatctttag caaaatccaa acgctaaaaa
     6841 gtttgtgaaa aaatattctt gataagaaaa tcccttgttt tcacggggtt ttctttttta
     6901 ttttgtgaaa tttcttttag aaaaactttg acagtatttg ccaaaaacgg taaaatagta
     6961 aggtaagaag aaagttagaa aggcaagaag atgtcaactt tagataaaaa tcttttgcta
     7021 gaaatgttcc gtaagatgga agaaatccgt cgcatggact taaaaattgc acaattagta
     7081 aagaaaggga aagtgccagg aatgacgcac ttttctgttg gtgaagaggc agctaacgtg
     7141 ggggctatgt tagctctcaa tccagatgat ctgattacct caaaccaccg tggacacggg
     7201 caagctattg ctaaagggat tgacctcaac ggaatgatgg ctgaaatcct tggtaaatac
     7261 actggaacct gtaaagggaa aggtggatct atgcatatcg ctgaccttga tgctgggaac
     7321 cttggtgcca atggtatcgt aggtggtggt atggggatcg ctgtcggtgc agccctcagt
     7381 cagcaaatgc aaaataccgg taaaatcgtt gtttgcttct ttggagatgg tgcgaccaat
     7441 gaaggtgttt tccacgaagc agtgaacatg gcttctatct ggaacctgcc agtcattttc
     7501 tattgcatta acaacggtta cggtatctct gcggatatca agaaaatgac caatatagaa
     7561 catatccatc aacgtagcgc cgcttatgga attcctggaa tgttcatcga agacggtaac
     7621 aatgtcatcg atgtctatga aggatttcag aaagctgtag accatgttcg cagtggcaat
     7681 ggtccagtct tgattgaaag tgtaacttat cgctggctcg gtcactcatc atctgaccct
     7741 ggtaaatatc gtacgcgtga agaagtggaa ttgtggaaac aaaaagatcc aatcgaaaac
     7801 ctccgcaatt accttattga aaataacatt gcaagtgccg aagaattgga agaaatccaa
     7861 gcgcaagtaa aggaagcagt agaagcttct gttaaatttg cagaggaaag cccattccca
     7921 ccgcttgaat cagcctttga agatatttac gcagactaag gagaaagaga taaaatggaa
     7981 acaaaaacaa tgtccttccg tgacaccatt atccttgcta tgtctgagga aatgcgtcgc
     8041 gatgaaaatg tgttcttgat gggagaagac gtcggtgtct tcggaggaga cttcggtact
     8101 tctgttggaa tgcttgaaga atttggtcca gaacgcgtcc gtgactgtcc gatttctgaa
     8161 gctgccatct ctggagcagc agcaggagca gccatgacag gacttcgtcc aatcgtcgat
     8221 atgaccttca tggacttctc tgttattgcc atggacaata tcgtcaacca agctgctaaa
     8281 acacgttaca tgtttggtgg taaaggtcag gttccaatga ctgttcgttg tgcagctggt
     8341 aacggagttg gctctgccgc ccagcactca caatctctag agtcttggtt tactcacatt
     8401 ccaggactta aggttgtggc acctggaaca cctgcggaca tgaaaggcct gcttaagtct
     8461 tctatccgtg ataacaactc agttattata cttgagtaca agtcagaatt taaccaaaaa
     8521 ggggaagtgc cagttgatcc agactacaca attccacttg gggttggtga aatcaaacgc
     8581 caaggaacgg atgtaacagt tgttacttat ggaaaaatgc ttcgccgtgt ggttcaagct
     8641 gctgaagaat tagcagaaga aggaatttca gttgaaattg ttgacccacg tacccttgtt
     8701 ccgcttgata aggatatcat cataaactca gtgaagaaaa ctggtaaggt tgttctggtc
     8761 aacgatgccc acaaaacaag cggctatatc ggtgaaattt cagctattat ttcagaatca
     8821 gaagcatttg actatctaga tgcaccaatc cgccgttgtg caggagaaga tgtgccgatg
     8881 ccttatgcac aaaacctaga aaatgcaatg attccaacag ttgaaagtat caaagatgca
     8941 atccgaaaaa cttataacaa agaatagagt tgcataagat aagttatgta aataaaataa
     9001 agctgacgag aaactttgta tcttttaggt gcagagctct tcgtcattaa tatcttagat
     9061 tagagcacgg gctaaaagct cggaaaaaag ataaatctcc ttggcttcat cgaagccatc
     9121 gtcgatttcc tatttttcag tcgcttttga cgccctttgt atcataaata gaattggaga
     9181 ggtcatggct gatgacaagc taagagcgac tcctgcagct agaaagttag cagatgattt
     9241 agggataaac ctctacgacg tttctggctc aggtgcaaac ggtcgtgtcc acaaagaaga
     9301 cgtggaaact tataaagaca caaacgtggt tcgcatttcg ccacttgcaa aacgaattgc
     9361 cctcgaacat aacattgctt ggcaggaaat ccaaggaacc ggtcatcgtg gtaaaatcat
     9421 gaagaaggat gttttggccc tgcttcctga aaatatcgaa aacgatagca tcaaatctcc
     9481 tgctcagatt gaaaaagtgg aagaagtccc tgataacgta acaccatatg gtgaaatcga
     9541 gcgtattcca atgacaccaa tgcgtaaggt tattgcccaa cgcatggttg aatcttactt
     9601 gactgcgcca accttcaccc tcaactatga agttgatatg actgaaatgt tggctcttcg
     9661 taagagggtt cttgagccaa tcatggaagc aactgggaag aagactactg taacagacct
     9721 tctttcactt gcagttgtta agactcttat gaaacatcca tgcatcaacg cttcattgac
     9781 agaagatggc aagactatta tcactcacaa ctatgtcaat cttgccatgg cagttgggat
     9841 ggataatgga ttgatgacac ctgttgttta caatgctgag aagatgagtc tttcagaact
     9901 ggttgtagcc tttaaggatg ttattggccg taccttggat ggtaaattgg ctccaagtga
     9961 gttacaaaat tcaacattca caatcagtaa tttgggaatg tttggtgttc agtcctttgg
    10021 tccgattatt aaccaaccca actcagctat ccttggtgtc agttcgacaa tcgagaagcc
    10081 agttgtcgtc aatggtgaaa ttgtgattcg cccaatcatg agtttaggat taaccattga
    10141 ccaccgtgtc gtagatggta tggctggtgc taagtttatg aaggacttga aagagttgat
    10201 tgaaacgcca atctcaatgt taatttaaga gcaagagtat tcatttttaa gatatagata
    10261 aaggaaggaa gacatggcct tagaagtaat tatgccaaaa gccggcgtgg atatgacaga
    10321 aggacaaatc gtccaatgga ataaaaaagt cggagaattt gtaaaagaag gagaaatcct
    10381 tttggaaatc atgactgata aagtcagcat ggaattggaa gccgaagaag atgggtactt
    10441 gattgccatt ctcaaaggag atggtgaaac tgtccctgta acggaagtta tcggttacct
    10501 tggtgaagaa agggaaaaca tcccaacagc tggagcagca tcgccagaag ctagccctgt
    10561 acctgtagca agtacctcaa acgatgatgg taagagcgat gatgcttttg atatcgttgt
    10621 gattggtgga ggtcctgctg gttatgttgc agccattaaa gctgcccaac tcggcggtaa
    10681 ggttgccctt gttgagaaat ctgaacttgg tggaacctgc ttaaaccgtg gatgtattcc
    10741 aaccaagacc taccttcata acgctgaaat tattgaaaat atcagtcatg ctgcaaatcg
    10801 tggtatcgtg attgaaaatc ctaacttcac tgttgatatg gaaaaacttt tagaaactaa
    10861 atctaaagtt gttaatactc ttgttggtgg tgttgcagga cttcttcgta gctacggagt
    10921 tactgttcat aaaggaattg gtacaatcac taaagacaag aacgtcttgg taaatggttc
    10981 tgaattgctt gaaaccaaga aaatcattct tgctggtggt tcaaaagtca gcaagatcaa
    11041 cgtccctggt atggaatctc cacttgtcat gactagtgat gacattcttg aaatgaacga
    11101 agtgccagaa agccttgtta tcatcggtgg tggagttgtc ggtatcgaac tcggtcaggc
    11161 cttcatgaca tttggttcaa aagtgactgt tatcgaaatg atggaccgta tagttccagc
    11221 tatggatgcg gaagtttcta agaaccttcg cttgatcctt gagcgtaaag gaatgaccat
    11281 cttgactggt actaaactgc aagaaatcat tgaggaaaat ggtcaacttc gtatcaaggt
    11341 tgaaggaaaa gacgatatca tcgcaagcaa agctcttctt tcaattggtc gtatgccaga
    11401 ccttgaaggt attggagagg ttgagtttga attggatcgt ggttgtatca aggtcaacga
    11461 atacatggaa acttcagttc caggcattta tgcaccaggt gacatcaacg gtactaagat
    11521 gttggctcac gcagctttcc gcatgggtga agtttccgct gaaaatgccc ttaaaggaaa
    11581 tcatgcagtt gccaaattga atttgactcc tgcagccatc tacactctcc ctgaagtagc
    11641 agcagtaggt ttgacagaag aacaagcccg tgagaaatac gatgttgcca tcggtaagtt
    11701 taactttgct gctaacggtc gtgctattgc atctgacgca gctcaaggtt tcgtaaaagt
    11761 tatcgctgat aagaaatatg gagaaatcct tggtgtacac attattggtc ctgcagccgc
    11821 agaattaata aacgaagcat caagcatcat cgaaatggaa atcactgttg aggaaatgct
    11881 gaagaccatc cacgggcacc caacttactc tgaagtgatg tacgaagcgt ttgcagatgt
    11941 tctaggaatg gccatccatt cacctaagaa aaaataaaac gaagatagat tagactggaa
    12001 ggttatttcc agtctctatc atataaagta aagggatatc atgaaataca ttatcaatca
    12061 ttcaaatgac actgctttta atattgcctt ggaagaatac gcctttaaac accttttgga
    12121 tgaggatcaa atcttcctac tttggattaa caagccatct atcattgttg gtcgtcacca
    12181 gaacactatc gaagaaatca accgtgatta tgttcgcgaa aatggtattg aggtagttcg
    12241 ccgtattagt ggtggtggag ctgtttacca cgatttaaat aacctcaact acacgatcat
    12301 ctccaaagaa gatgaaaata aggcatttga cttcaagagc ttctcaactc cggttatcaa
    12361 taccctggct caactcgggg ttaaagctga gttcacaggt cgtaatgacc ttgagattga
    12421 tggtaagaag ttctgtggca atgcccaagc ctatatcaac ggccgtatca tgcaccacgg
    12481 ttgcttgctc tttgacgttg atttgtcagt cctcgcaaat gcccttaagg tttcaaaaga
    12541 taaatttgaa tcaaaaggtg tgaaatccgt ccgtgcccgt gtaactaata ttatcaatga
    12601 attaccaaaa aaaatcacag tcgaaaaatt ccgtgattta ctcttggaat acatgaaaaa
    12661 agagtaccca gagatgactg aatacgtctt ttcagaagaa gaattggccg aaatcaatca
    12721 catcaaggat actaagtttg gaacttggga ctggaactat ggtaaatcac ctgaatttaa
    12781 cgtccgtcgt ggaaccaaat tcactagtgg taaggttgaa gtctttgcta acgttactga
    12841 atcaaaaatc caagacatca agatttatgg tgacttcttt ggtattgaag acgttgctgc
    12901 agtagaagat gtccttcgtg gggtgaaata cgaacgcgaa gatgttctta aggcgctaaa
    12961 aaccattgat atcacacgct acttcgttgg tattagccgt gaagaaattg ctgaagcggt
    13021 agttggataa atcaaaaaga agttggccaa ctaaccaact tctttttttg atatttattt
    13081 acataattta aaatacgtaa aatcataaac tatccagagc attcttttgt tcatcactaa
    13141 caatatgggt atagaggtca gtgacttgtg tgctagcatg tcctagttgg tgactgacta
    13201 aaacttgtga tttagtcgca tcatagagcc tagttgctag tgtatggcgc agtttatggg
    13261 gtgttacacg cactttaaaa tcctctgagt atttagcaac cattttctca acgctagaag
    13321 catcgatacg attaggaaca cctctgtaga gagttaaaaa aagggctgta tctgtttttt
    13381 ccgttttata gcgttgattc cgaatggcca gataattctc taaataaggt ttagcaaaag
    13441 cagcgacatt gactgagtca cgtttgccac cttttcgagt aacatcaata accatcattt
    13501 ttagattgag atctcttaga tctagattaa cagcttcaga taagcgaaca ccagatgcca
    13561 agagaagggc aataatggct aaatctcgtt ctttattttt gttgaatgat gagagagctc
    13621 gatttgaaag ctgttgtggg tgctcttgat cgatataagt tagaaaacct gctgtttcat
    13681 cacctagaaa gagtttttgc ttgatatttt cagctctggc agcaagggtt tctttctttt
    13741 tcttggttga aacttttttc attacattac gatagaaata aggttccccc tgatcgtttt
    13801 caacctcctc ggttagatac ttgtaaagac tagaaagtgc tgataaggtt cgattgatag
    13861 ttgtctgtga aacaccttgt tttgttgtat tagcattcag caagggacgt tcacgtagat
    13921 aaaggataaa ggattccatg tctttcttag acatattttc caaaactgat aaaggaatat
    13981 cggatatttt atcagcgttt gaaataccag actccaaaac ccagctgaaa aatcggtcat
    14041 attccttaag atattcgtac agggttgtaa aactgtaggg cacagccagc ttagattggt
    14101 agtattccag aacataccag ggcatgagtt gttttagttt gtcgattcgt tccagtaaaa
    14161 tctcacgttt catgtatttt ctccataatt aagtatacta gtagtatagc atagacttgt
    14221 atgtttttca agaaaattat agtttttcag aaagatgtta taggagtttt tcaaagtgat
    14281 aaaaagactt agacctacaa acaaaacaga ataaggaaaa taataaaaat ctcacccact
    14341 aaacttctgt taatactaca taactgaaga gctatataag gagctatgag atacaaaaca
    14401 cattgtataa tagattgaaa ctagaatagt acatctggac ttctaaaaca ttgctagaaa
    14461 ttgatttgat tgtcctgatt gttttatcct atttctattt catttctcta tataattgct
    14521 attgttttct ttttcatgat tttaatctta ctgtacagat ttgatacagt aaactccttt
    14581 ctagctttat actttatcat ttctaactta attatagtct tatttttaat aaagttcaat
    14641 tatttatatg taaaattcct catcagtaaa aaataaccga tctcatttct gagaatcggt
    14701 tttctaaata aatcaaactg atcatttaca taacataaat tatgtaaatg atcatactac
    14761 aacaacaaat ctttgacttt tccaatttca ctttttggaa taaccaggtg aatcatatca
    14821 cccagataca ttctggttga gccgttaact gtttggctct tgccattatg gacttgagtt
    14881 gtgatgagga cgttgtgtgg taagttgagt tcatgaactt gtttcccagc aattttatca
    14941 gaaactggta tttcgataag tgtaacttct ccttcgctag atacttcttc tggaagcatt
    15001 ttttccagca tggcttcata gactggcgta cctttgagca aatccatgat aatataagaa
    15061 acaagagtga caagaccaag tggcataagg ttgcgaatat ctcctaccat ctcagttacg
    15121 aggatcatag cggttaaggg agcttttgat atggctccaa aatagccact cattcctaga
    15181 atgacaaata tagggaattg ctcttgactg acaagtccaa gattgacaca gataacacca
    15241 actaaggcac caagcaaaga accaagagct aaaatgggga ggaaaattcc tcctggcagt
    15301 ccacttccat agctaatcat actccaaata aagcggatta aaaagtaagc taataaaact
    15361 tggaaactaa aattttgttc agttaaagaa aggacaagct gatttccgcc accaatgatt
    15421 tgaggtaaga agattccgac tggtatgata aggataaaag ccaagatggg ataataagcc
    15481 ctatccaaat ggattttttg accaatcaag tcataaactc ttccaacgtt taatacagct
    15541 ttctcataga gaaaacctga aaatccaagg aaaattccca tgacgagata tatccaatac
    15601 tggtctaggg tcatgggagg aatgttatct ggcatatcca atactggtgt caaaccgaac
    15661 atgagtagag acacaaagtt tgctacgatg ctggctgcta gagttgagac ccagaaaaag
    15721 cgcgaaaaat ggtgatagac ttcttctaca acaaagagaa gtgctgcaat aggagcatta
    15781 aaggctgcgg ctaaacctgc tgcagctcca ctggcaatca aggaacgttc ctctactgga
    15841 ctggatttga gccacttggc aattccttta ccaccaactg ctccaagttg aatgctgggt
    15901 ccctctcgac ccagcatgag tccactggca atagcaagaa tacctagcac atattttttc
    15961 caaagaatgc cccaccagtt gagggacatg aggcctttca gttcggcttc gacttgagga
    16021 attcctgagc ctttaatatc tttttctgac cgtgttagtt tggcactgag ccaacagatg
    16081 agtatataaa acaaaaccag tacaaaaaga ttgcgcacta agtacccttg atcttgataa
    16141 actccttgta tcaggtggaa gcccttttca attaagaaac gaaaggatcc gacgataatt
    16201 ccaacgatga ggccgacaat gattcctcga ccaacttggg atagtatagt gctggatgca
    16261 aaggcgaatt ctttcttaga acggactatt tccgactgtt cctccatggt atttcctttc
    16321 aattaacttt cttttttacc taaaaccagt gatttaacgg gttcaaagct ggttcggtga
    16381 attggggtaa ctcctagttt tgtgaggcct tccagatgtt tagctgtgcc atatcctgca
    16441 ttagtagcga aatcatagcc agagaactgc tgatcgtatt ctttcatcaa ttcatcacgt
    16501 gttaccttgg ctactataga tgctgctgcg atagagaggg agttggcatc tcctttgata
    16561 atggaggttt gtgaaatggg caagtccagt ttcatggcat caatcaaaag gtgctctggt
    16621 tgagggctga gctgggagat tgcttcttgc atggctagtt tggttgcttc atagatgttg
    16681 acttggtcga tgacctgatt atctatgata ccaattccaa tcgacaaggc ttggtcttga
    16741 acggcttgga aaatctccag atgtttcttt ttaggaattt tcttgctgtc gttgagacct
    16801 ttaatcttac aatttttagg taaaataacg gccgcagcga ctacaggacc agcaagagga
    16861 ccacgaccaa cctcatcaat acctgcaatt aaggtcaatc cttgcttata aagttctttt
    16921 tcataagaaa gcatggattc caagcgcaaa ttttcatcta attcagcttg aatggctctt
    16981 ttacgcttgc tgatttcctt ttgaactcct gagcgattat ccttttcaag ctctaaaaaa
    17041 atagggcttt ctaactcctt gactgtcaca aggagttctt tgatttcttt aatcgttgcc
    17101 atcgaggtct tccaatgtat ctaaggtata gttaccgagt ttgccatcac ggacttcctt
    17161 cacgaagaga ctgtaaaaac ggtcatagtc atcacggaaa ccgagggcgc gggtcatatc
    17221 cataataatc acaggcgctt cttcttcaat tttcatttgt ttgaagcgtt cagccagctt
    17281 ttctggataa tgttctttga aataattgat accaaaaatg gtaacctcat ccataggaag
    17341 caactgatcc ttgatagctc cagtcaatgc caacttaagt gcaacagttt catcctcaaa
    17401 cttaggccag agaatccccg gtgtatccaa gatttccaga tctttattgg ttttaagcca
    17461 ttgttgacct tttgtgaccc ctggcttgtt tccaacaaca gcaatctttt taccagccaa
    17521 acggttcatc agagttgatt taccagcgtt tggaatccca ataatcatgg tacgcaaggt
    17581 ttcaatctga atcccacgtt ctttctggcg agcaatctta tcagccatga gcttcttggc
    17641 cgcatctgtt acaactttta cagtcacttg ctctttggag ttgatagcta gcgtctggat
    17701 tccttgtgat tcaaaatact gacgccattc cttggtcatt gctggatcag ccaagtcggc
    17761 cttgtttaaa atcaagagtt ttggtttatc accaacaatc ttggtcaaca taggattttg
    17821 actagataga ggcaagcgtg catctactaa aatcgtcaca aaatcaacaa attttaaatt
    17881 ctcctgcacc tgtcgacgag ctttagacat gtgaccagga aaccattgaa tagtagccat
    17941 tgagtttttt cctttcatag caaggattta gatcccctat tttattttac tattgtttga
    18001 acatagagag ttttcaaatg aatgatgtcc aaacagttct tgttttatga catagaaatc
    18061 tactttatat tatatcatgc cttctttatt ttgtccgatg atagcctttt accctatctt
    18121 ttaccctatc ttttacccta tcttttaccc tatatagaaa aaagccatca aatgatgact
    18181 tttcagaggg agcaaaaaac tgttcccgtc atattatgaa ccaaaagaac taaactacca
    18241 acagctaata ggcctaaagc tgtaagctca gaagttgatg aacctgttgc aggaagagtt
    18301 tcctgctgat aaataagatc ataacttact tcattatcag taggaattcc tgcttgaatc
    18361 ttggtttgtt cttcatcacc tttttaaact ttatttccta atagtagaca ctatttttta
    18421 ttctcaaaaa ttgaacttct aaaatcattt gtttggtcaa gataggcttt aaagattgct
    18481 ctcttgagct tgtggacttc actatctatg tctggattgt agttattcca atggtagtaa
    18541 ttgtgttctg catccttacg aacagcaacg tccattaatt tctgtaattc atctacactg
    18601 cttgtagttt tcttggcaaa tgtttgccaa ggctgtgttg tatcattaaa agtaactttg
    18661 ttcaatctat caaactgatc ttgtcgttct tgatacatag ctttcttaaa ctcactccaa
    18721 gtatgatatt ggttattaaa taccttttcc aaaaccaagt catctgtaac caaacctctt
    18781 gttttaccgt agagattgat tgtcttgccc ttttgtttgg cttcttcttc gtattggttt
    18841 gagatatatg gtaccatacc atctttaaag cctttagcag ctagtagttc ataggctata
    18901 cgacgtccca tcaggtcacc tggtgttcct atatcattac ttaatgcagc ataaatcggt
    18961 gcaaataact taatagtgaa gtagccattt ctttcgtatt tacctgaggc atattcccta
    19021 gacgaaagaa tattattatc aatcaaatca ttgaatgaac gtagtctttc aacttcttct
    19081 actgttagat ttctgacaac atttgttgca tagaccttat ttccatcagg atcaggatgg
    19141 tactcatttg taacttttct aagaagttgt tgtttttgat tcgtatccaa tttaagaatt
    19201 gaatttcctt cgagatattc caacatataa acaacgtcaa acatgttgtg gacatattgc
    19261 ctcaaatcat ctgcattatt aaatcttgta gttggatcaa gtacttgtaa tcgtcgactt
    19321 tctgtactat cagattttga atgtttcaag atggagttga tggtaatggt cgcatcatct
    19381 ggatggtctg gtgcttgtaa taatccttta gcaaagaact ctggtcccaa gccacttctt
    19441 cgaccatatc ctccaagata aatgtcctga tctgagtcat gtgtcatctc atgcgtataa
    19501 gtaatagctc catccttatc caacattcga taacccatat aataaactgc atcacctgta
    19561 gcataagcac cgtgttgatt atgcccaact ttatttccaa caggtccaaa gaaatgttgc
    19621 attgcaggat ttggattatc aaaatctgcc acttctgtag ctttccctac ggtattatca
    19681 tcgccaaatt tataagcatc gtaaagcaaa atatttctat aaagtttttc acgtgcattg
    19741 tcgtctaaaa tacgatacca ataatcgtag tgatctcgct gacgtttggc tgtttcacgc
    19801 gcattttctt caacaaaatc attgagagcc ttgcccgctt tatggtcact actgcggtag
    19861 cgatcataag ctccaaatcc tagactagac atggtcgaga tgacaaatac ggatctctct
    19921 ggcaaggtca ggagaggcaa gaccatattg cggtatttcc atgtggcact cgtgatacga
    19981 tcataaacac cgatagaata cttggtgcca gctaaccctt gcttcgtttt cacctcttcg
    20041 atagtggatt tttcttcgac aatgtaagcc ttagtctctg atttaaacca gtcattattg
    20101 cttgtatttg gtaaaaagac ttttcggtaa tgttccagcg tgctaaacaa atctgtcgtt
    20161 ccatgttgac tggcaagact gataccataa gtatcgacat tattcttagc tagaagattg
    20221 ttaaagccag atttacccaa ctcaatcaga gtatctaatg gtgaagcatt ccccttacca
    20281 aagaagtcca aatggtacag aactaggtct ttgacattca cctgaccata gctaaagtta
    20341 taccaccgtt ccagataggt caagccaagt agcaaggctt ccttgttgcg tttgatttta
    20401 tctacaagat aaccttcagt gacggggtta gcactagcca gtccagcatc cgctgacaag
    20461 agttttttca aactgtcttc cagttgttgt tttgttttgg cgaactggtc ttctagatag
    20521 agctcagttt gcttgacgtt tggagaaata cccagcgtct ttctgatggc ttctgaatga
    20581 tagtcaacct tttgtaagtc aggtaagact tgcttgatga tagaggtttg gtcatacagg
    20641 aattggtttg gcgtatagag aagtccagta ttgcccagac tatattctgc taatttggcg
    20701 aaatcattct ggtatttgag atccagcttc tcagataaat catccttgta gtgaagcaag
    20761 agtttgtttg cagtctgttt gttagaaaca atgtctgtga tgacttggtt gtccttcatc
    20821 atgactgctg acaagagttc tttttgatat aaaagactgt tctcattgac caggtttccg
    20881 tatttgacga tggttgcctt gttgtagaaa ggtagcaatt tttcaatgtt tttataagtc
    20941 aagttgcgct tagcttgata ataggccacc ttagaaaaat cactgtcttt tttgccactt
    21001 gttgaaagtg gctccactgt tggtagaatg agaggattga tttctgcttt tttgcttgca
    21061 atttgagaag catctagcat tgttcctctt tcttcaaagg attccttgct gacgacctca
    21121 tccttgacca aggtgacatt gtagactctg ttggccttgc tgctgaatgt gtcctttacc
    21181 ttcatttcgt tatagtggta accagtgatg gcatttccgt tggttacatt aacatcgctg
    21241 agaacattgg tcaaacttcc agcatgccta acatcaccag aagttcgatc ccacaaattg
    21301 cctgccactc cagcgactct accaaagtgc ttgacattgt tgatatcacc ttcagcatag
    21361 ctatcttgga tctgtgcatc tcggtctact aggcctgcaa gtccacccac agtctgatct
    21421 gaagtatttg tgttagatga aatggctact gtcgcttttg acttagtaag taaagccttg
    21481 tcacctgtca aatgaccgac cataccaccg atattgtagg cagcagtcgt ttcataagtg
    21541 ttgataattc ttcccttgaa actgctctct gtgatgcttg attgctcagc cttagccagc
    21601 aaaccaccga taccacgttc accagccaga acaccatcga cgtgaacttg cttaattttt
    21661 gtgttattct gagcttcatt tgccagtgaa ccgatatcat ctttccctga aatagcaaca
    21721 ttttttagac tcagtttttc tactgtagca ccactcaagt tttcaaacag aggttttttc
    21781 aaattataga tagcataatt cttgccatct ttttcaccga ttaaacgacc agtaaaggtg
    21841 tccttgatat aggatctttc atcaggacca agctccactt cgttagcatt caggctggcc
    21901 gctaaatgat aggttccaga gggattttgg tttatagctt tgaccagatt actaaaggaa
    21961 gtaaagtttg ttgtttcttc tgttcccttc ttagctagat agaaggtaaa attatcttta
    22021 tatctgcttt ctatctcctg ctgaagcttc tctacttttg ctgtgatttt ataaaggatt
    22081 ttatcatttt ttctttcctc tgatattgat gctactggta ggtatacatc tttgaatgaa
    22141 gaagatttca ctttaacaaa gtagctattt ggattgcttg gaacttgctc taacgaaatg
    22201 tgttgtttat aagtaccatt tgacaaactg tataactcta ggtcggaaac atttcttaat
    22261 tcaagtgttt tctctggttc ttctaccttt ttatcagggt ctagttcatt ttcttgttta
    22321 atttcttcgt ttccatttga attggatgtg tttgattcgg ttgaaacatc ctcagttgaa
    22381 tttccgtttg atggttctgg ttctgtttgt ccattctctg atgttgtatt acctgaattt
    22441 tctggttttg ttgcagttcc gtttttttct ggttgatttg attcttcaac tggtggtttt
    22501 gaatcactag gtttattgga tacttctcca gtattttcgt tagctatttt cccagagttt
    22561 gtttgtgttt cttctgcagg ttgaactggt ttttctgttt cttgatttga ggtaccttct
    22621 actgtgcctt catttggatt tactggaact tcttctacag ttttttctga attttcattt
    22681 ttagagtcat tatgttctgg tttatttgat tctccaactg aggttgtcga atcactagga
    22741 ttactggaca cttccccagt atttttgcta gatgtatctg gtgatacttt ctctgaattc
    22801 gttgttgatt cttctgcagg ttgaactgga ttttctgctt cttgaattga ggttccttct
    22861 gtagtacctt catttggatt tactggtgtt tcttctgttg gttttactgg aacttcttca
    22921 gttttttctg gaccttgttc tttggtcttc tcaaccggag tttcaggttt tacttgctca
    22981 atattaccct tatattctgg aagcggtgct acctgctctg gttcaccttt atcacttacc
    23041 acagtatctg gcgactctgg ttgaacctca gtctcacctt tgtcggtcac aactgcttcg
    23101 ggtaatgtag gttgaacttc tggttcgcct ttgtcactta ctacagcttc gggcaactca
    23161 ggctgaattg cgggttcaac aatagctcca gactgtacgt ccttatgttc tacaccagtc
    23221 tcaggttgtt cctttataac ttgagttttt ttagtacctt tttcgactat tcttggacta
    23281 ggcgcagtcg ttgaagttga aacaatttct cgcgaaactt cttccttgtt tacagagaat
    23341 attctgacga tttcaacttt cttacctaat ttaccttctt gttttactct tacagttcct
    23401 tcagctaaat caggattttc ttgaatttct tcttgaaaat ctatttttgt ctctatagtt
    23461 tcctcacgat ataagagttc aggtttgttc aattgacctg ataaaacttc atcctgtgga
    23521 tttaatgtat ttaccccagt cttttctttt ggagaaatct tctcctcttt cttcgtttct
    23581 agattcttat gttcggctaa ttgttcttga gaatctgaag attgtttctc ttcttttctt
    23641 ggattgatta attcagtaga gaaaggtttt tcaactactt gaacttctgt cggcttagtt
    23701 gaagaaacag gtgtttgttc ctgaatagct tgtactgttg atggatggtc tacaaaattc
    23761 ggtgtaacat tataatccac cttttgttgt tttgtaggag tggcaactga actcttttga
    23821 ttacttactt cagactcaga agtcgttttt ccctctttga tatatccaat ataagtgtaa
    23881 cctgaaatct ctttaggaag aggtaatttt tctccagagg tcaattcata gtccgtattg
    23941 taatttagca aaagatgatt ttctaaagca tggactgaaa ctaagacacc atttcctatc
    24001 cctgcaacca atactaaatg taataccgtt ttattcttaa cctttttctt ggaaacagca
    24061 aaaattaaaa ttcccatagc agctaagcta gcaccagcaa ctagggcttg cctctcattc
    24121 ttgcttccag tatttggcaa ttccgccagt tgattttgag aatttaactt ataaacaaga
    24181 taataagttt catcatcatt ctccacgtat gtcggaatat catagacaag ctgcttcttt
    24241 tcttctgatg atagctctga atctgccaca tatttatagt gaactcccgc agtttcttga
    24301 gcatccacag atgaactagc taatacagac ataaaaaata aacttgaaat cgttgcagat
    24361 acaagtccta ctgataattt tctaaatgaa aaacgctctt gtttttcacc aaaatacttt
    24421 tccattattc ctccttgaaa taaaatttat atatgttaca aagaccttta ttatattagt
    24481 gtattatcta ttatctatag aaaaggcagt ataccttaat tatactctta atttacaaaa
    24541 aagtcttaaa attgagatgc gctttcatac tttgttttat attatttgga ggtacaataa
    24601 cacctaccat gaaatttaca cggtaggtgt tactcatatc actaatcgtt ctaaaaatgg
    24661 tttgaggcag ttgaggagaa ttccttctat ccagcttcct tgtgctgatg agcgatggtc
    24721 ttcctgcagg ctttttttta gaaaatctcg gacttgttct ggtgcgattt caaattcaaa
    24781 ggctttcatt ttatagaaaa agtcgatgag atgatctgac aggtattcag ttgaaaaggg
    24841 tacttcacca ctttttctat attctaataa gagtctagaa aatcgagctt tttcttcagg
    24901 aagctcacga aaataggaat tgaggagcca agtctgcttc tgttttcttt caattggatc
    24961 ctgactggca attcgttggt ctttttccag ctctttttgg tattgtttgg ccttgatagc
    25021 ccgttctgct ctatttttac caaaaagaat tttttcccac ttgcgttctt cttgagtcag
    25081 ggtctctgta aagccaaagt aatcttgata agcacgctct gcgggtccca tggctagaac
    25141 cagattgtct gcatattgct tggcgatttt atccctcttc ttgcgttctt tctctgcctg
    25201 gatacggagt tcttgttcgt agtcaatttt ctccttgcct agctttacaa ggtagagttg
    25261 gtcatccgat ttcccaagta aaaagggttt gatacacttt tcaaggactt cttccatccg
    25321 agcctttttc tttggttccg ccttggtcca acttcctccc tgaaagactt ctaggaaaag
    25381 ctggtagtct ctctcaggcg caaattgatt gccacgattg ggtttgaaaa cacctttttc
    25441 ccagagccat tttagaagtc gctcgtcaaa gtcactttta ttgaccttga ttttttcctt
    25501 tttctgagct tttctggtta gattttcaac ctttctgagc agtttttctt cctcttccaa
    25561 ttgctggtca agggacaatc gatgaaaatg acgaacacag tcgctaccaa ttggaaagag
    25621 gcgttggcct gtgacaccgt taaagagttc ataagcgtat ttgatgacat ttccacagac
    25681 acaattgcta cggccgatac cgttaaaaat caaggaaact tcattccatt ccttggtagc
    25741 ttgttcccaa gtatccgctt ctgaagcctg taaaaccgca ttgtgtaggg attttctaac
    25801 tggaagtgtc atgaggtctc ctttctaata ctcaataaaa atcaaagagc aaactagaaa
    25861 gctagccgca gtcagctcaa aacactgttt tgaggttgtg gatagaactg acgaagtcag
    25921 taaccatata tacagcaagg cgaagctgac gtggtttgaa gagattttcg aagagtataa
    25981 gttatacttt tacaacttga acctcgtctt taccgagtaa aatcaagtat ttttcaatat
    26041 tttcaatcga ataggctcgt gataaagcct cttcgtatag agctaactga ccacgatagc
    26101 ggtctacgag ttgacttggt tcatcatagc ggtctgtctt gtagtcgaac agaacaattt
    26161 tgttttcgta aagcagatag ccatcaagga taccacggac aacaaagtct tcctgactct
    26221 tttggtctcg tttgagcatg gagaaaggtt gctcgcgata gagatggtcg gtattagcaa
    26281 gaatttcctg accgagtact gtgtcaaaga aagcaagaat tttatcaaga ttgatcttgt
    26341 ctctgacagc ttggctagtt tgaacttgtt tgagtgtttc tgttaggcta gcaagggtta
    26401 gttgctggct gaggtcaatt ctctgcatga gttcgtgagt agcactacca atctcagctc
    26461 cagttacctt ttcttttgtt gaaaaatctg gcaaatcgaa gctgattttc ttgcctactg
    26521 actgaccttg accagcaatc tcgacacctt ccatatccat aactggttcg tagaatttct
    26581 tgatttgact tggggtttga acactaggaa gttcaatagc tgcgcggtga agagtattat
    26641 aaacttccac ctccttcagc atttccagag cttctttgat ggtatctgac tgacgattgt
    26701 ctgcttggga gctatcttgg agaggactct tggtttccaa ctctccgata gcttctctgg
    26761 tcaactgatc ttcgccaata aaacgataac taaagttgag cttgtcctta gtaaacactt
    26821 tactgatagc ccaaagccaa tcttggaaat tccgtgcttg cagtctagta ttgctattta
    26881 gtttcccatt tttggctgct gggtattgct tggcttccag cttttcacga gaacccttgc
    26941 cgacaagata gagctttttc tcagcccgcg tcatagcaac atacagcaaa cgcatctgct
    27001 cagaatagct tgctagctgt aattcctctt cattctgcct ataggtcagg ctaggaatgg
    27061 agagtttgat ggttttagga tagtggtctt ctactgcccc tgtctccatc ttggcaatat
    27121 atttgacacc aagaccattc tgacgactga gaatgacttc tgacatagag tcttgcttgt
    27181 tgaaatcttg atccatattg aggataaaga cgtaaggaaa ctccagcccc ttactcttgt
    27241 ggatggtcat gagctctact gcatcttttg gcggtgcgac ggccacgctt gccaaatcgt
    27301 gctgggcttc taagacttgg tcaatcatac gaataaaacg cgataaacct ttgaaattgc
    27361 tcttttcaaa ttgatcagca cgcagtgcta gggcatagag attggcctgc ctagcaggac
    27421 cattcggcaa agccccaaca tagtcataat aaaaacggtc gttgtaaatc ttccaaatca
    27481 agtcatagag agagtgggtt ttggcataca agcgccaaga agctaggata tccatgaatt
    27541 gctttagttt ttcagctaga gctgtgtgaa tcaaaccttt ttgactactt gccatttttt
    27601 gtgcattgac cagtttctca tagagatttt cgtggacttt atcctctgct ttctgaaggg
    27661 acaaacgtgc tagctcatcc tcatcaaaac caaacattgg agacttcata agggcaacca
    27721 aggcgtagtc ttgcagggga ttgtgaatga cacgaagagt gtctagcatg acttgcactt
    27781 ctagggattg gagataattg tttttctctc cgtcagtttt gacaggaatt ccgtactcag
    27841 acagggcgag gagaatctgg tcattacgac tgcggctgga ggtcagaagg gcaatttcct
    27901 taaaggcaac acctttttct tgatgaagtt tcagaatctc cttgataact aagcgcattt
    27961 cgcctgttag tttcgtttct gtttgactct cttcttcctc acctgtatcg tccttatcgt
    28021 agaggagaaa ttcggccttg ttgtctggat tgggagtcag tttggtattg gcaaaaacaa
    28081 gctggtgcat gttatcatag ttgatttcgc cgacctcttg gtccatgaga cgttcaaaga
    28141 catcattggt tgctgacagc acttctgaac tactacggaa attttccttg aggagaatga
    28201 gcttgccttc ttgaggattt tgcgcatagc gttggaattt ctcattgaaa atctgcgggt
    28261 ctgcctgacg gaaacgatag atggattgct tgatatctcc caccataaag cgattgtggc
    28321 cattagacaa caattccagc atccgttctt gaatatggtt ggtatcctga tactcatcga
    28381 ccatgacttc atggaagcgc tcctgataag actcacgaac ttgtgggaaa ttctctaaaa
    28441 tctcaatggt gtaatggctg atatcagcga attcaaaggc attttcctgt cgttttctct
    28501 gacgataagc ctctacaaaa tcgctcatga aagattggaa ggttttagct agtttccaag
    28561 tgtctccatg ataacgttct tgatagtcga gaatcgctat ctggtctgat aattgtccta
    28621 gtttagcaaa ctgggtcttt ctctcttcgt tgtaggtatc agccaggggc ttcaaatcag
    28681 ccttacggct ggcattagtc agagctcgac cgtttttctc cttagagatg gcgacaacac
    28741 gcgcaagcac tgcctgataa gcctgactat cggactcctg atttagggag tcaatttcat
    28801 ccagaattaa ctgaacattt tctaaatagg cagcctttgc aaactccttg gcatcgttat
    28861 ccagatggta acggaaaaag ctttccaaat cccaaagggc ttgtttgatt tgctcagtca
    28921 gtttttcttt ttcactggta aaatcagctt tctcaaatcc tttgaggaaa gattcactca
    28981 gccacttttg aggattactg gtggattgga ggaagtcata gattttatag acctgctggc
    29041 gcagaccccg ttcgtccttg ccacgcccag caaagttttt cagcaaatga ctaaaggtct
    29101 ctttctgttt accttggtaa tgcgcttcaa agacctcatg aaagacttcg ttttcgagaa
    29161 gaagttgctc gctttggttt tgtaaaatac ggaaattagg tgcaatatca agcagataac
    29221 catgtttgcc aaggaatttt tgtgtgaaag agtccatggt tccgatggca gcgttgggta
    29281 ggtctgccaa ctggcgactc aagtgttgtt tgagctcgac atcatctgtt tcttggattt
    29341 tcttgctgat ttttttctct aaacgttctt taagttcagt tgcagccttg acggtaaagg
    29401 ttgagataaa gagttgagaa atttcgacac cacgcgccaa ttggtccaga atgcgctctg
    29461 ccatgacaaa ggtctttcca gaaccagccg atgctgagac caggatattc tggccagaag
    29521 tgtagatagc ttcgatttgc tcggcagttt tcttctgttc cttgctcgaa tttgcttctg
    29581 cttcttgcag tttttgaatc tcctcctcac ttaaaaaggg aataagcttc atcgattcaa
    29641 ctcctctctt attttttcaa gccaagcttg cttgagtttt tctccgacca gacgcttgct
    29701 atcagctagg tccaactttt ttaggaaacg ggcttggccc agatggtaat tggcttcaaa
    29761 gcctgtaata gcctgatgtt gctggacgta tggggcaatg cttctgccat tttcagtata
    29821 aggattgatg gcgaaccggc ctgctaaaat cttctcagca gctttcttgt aaagataggc
    29881 attgtagtcc agtaggagct gaaattcctc atctgtcagt tgattagcct tgtttttgtt
    29941 ataaaattcg cctaaataac tgctttcttt ttccaagaag agcccttggt atttcataga
    30001 tttgctggct tctaccactg ctcctgcaag attttttacc gccatcagag attggacagg
    30061 ttcagccatt tccaagtaca tggcgccgaa aaagttctgc tccccttctc tttttagggc
    30121 agcaagatag gttggtaact gagaattgag cccattaaag aaatgaggaa actggaactg
    30181 agtcagactg gatttgtagt ctactactcc tatcgctcca ttagctttca aacggtcaat
    30241 ccggtccacc ttgcctcgta caaagacact gcgtccattg tctaattgaa taaaggcttg
    30301 gtcttttcca ccaaaatttg cttcttcttt gatggtttcg atggctggat tgtgtcggag
    30361 aatatgtcca gtcgtccgtg caacatcaag caaaacttcc ttggtaaact gggcttccaa
    30421 actttcttga taaatagctt caaattcgcg ttcttgactg gtttcttgaa tagcttgttc
    30481 tagacgttgg tcaaaggaat cttcattagg caactgtaag gcgcgttcaa agatacgatg
    30541 caagaaattc ccgtgactac gggcatcagg atgcaaacgt aattcctcct gcaagcctaa
    30601 aacgtagcgt aggaaataac tgtattcatt gcgataaaac tctgtcaaac ccgacgtaga
    30661 caggtaaaac tcctgtttgg caggatagag agcttgcaag gtgtccttgg ctaaggtctt
    30721 gctgcttgga ctggttggga tagctggatt ttccagacct tgctgatcta gttttttacc
    30781 tatgacacgc gacagaacct tgacaaaagt caaatcttgc tcagtatcgc tcatctcacc
    30841 ctgctggtga taggcaacca gactagacaa aagactgtga taggacccca tatcctcctt
    30901 agacagtctt ttgtgattca tcctcttctc tctccgccta aatccaaaat ggatcaactc
    30961 ttgaagatag gcagattcct tactttcact ttcgttaaaa aggcttggag ccgacaagaa
    31021 caactgctta cgagcagaat tgaccaagga aagcatagtg tagcgatttt tcttgagatt
    31081 ttcactgctg gcaatcagta attgaacgcc ttcttcggtc gcttggttta ggttttgcct
    31141 ttcttcatct gtcagaagac tggtgttttg agaaattttt ggtaaattgt cctgagttag
    31201 tccaatagca tagacaaagt cagcagtcaa tggtgcaatc aaatcgtaac tctgcaccag
    31261 aacagtgtcc actgttgctg gaatggtacg gtattgggac aaactcattc cagaatggag
    31321 caaggctagg aagtcttcca gactaacctg tgaaccagca aaaacagtcg caaattgttc
    31381 taaaacatgg cagaaagcct tccaaacttc ggtttgtctt tcctgttcta cagcttccaa
    31441 agtggttgtc aaatcttgta actgcttagt cacagctcct tcttttagaa agacactcca
    31501 tttttgtagg aggttttcag ccttttgttt tcggctggca aagagggttt caagaggtgc
    31561 taaaattctc aggcggagga cattcaaacg ctcaagatta aattttccat ggtgggattt
    31621 ggtgaaggtt tgctgaaagg ctggcaagcc attgatacca agatagcgga tatattgctc
    31681 aaaagcatca atatcagact gactgaggtc agtatacaaa tcagttctaa gaagattaat
    31741 caaatcctcc tgacgaaaac ggtaacgttt taaagctaaa atagactcga caaactgagt
    31801 caagggatga tgagccatgg cttcgcttct accaagataa aaaggaatct gatactggtc
    31861 aaaaatagtt ttgagagata actggtaaga agctacatcc cccaagagaa tacgaaaatg
    31921 cttgtagctc aggtctgagt tctcatgtaa tttctgacga atactacggg ctactagctc
    31981 caactcctcc ttttgcgtca aacaagacca gatttgtaaa ttttcacggt ctttctcatc
    32041 gacatccaaa gcgagttctg aaaagtcata agaagactcc aacaaacgag agaccttgtc
    32101 aaaactatcc atcttctcat gagtttgaga acagtcctga gcaggcgttt ggtatttaga
    32161 agccagatga tggagaaatt ttacgctggc ttggtagaga ttgccctcgc taaaaggact
    32221 ggtataggct ttcttactag cataagcccc gataacaatc tcaacacctt tgccgtgaag
    32281 taagtccaca acccgctctt cctcagcaga aaaacgagta aagccgtcaa tgaccaaggt
    32341 gatttgatta aaatcactac ttaccttgtc attctcaata gcctcaatca aatgggacaa
    32401 ctgacttccc tgggctaact gaccttgatt aagataggct gttactttct caaaaatcaa
    32461 gagtaaatcc gtcctcttat cctcatctgt taaattctcc aagtccaaaa aactcatctg
    32521 agatttggtc atctcatggt aaagctcaat taactgctgg atcaattgag gatcctgctt
    32581 aatagcgcca taaacacgca agtccttggg atcgagttcg gcaaggcatt tgtaaaaggc
    32641 caacccaaga ccgatatcat caagagtagt tttaactggt aaatcattca agaccagata
    32701 acgagccatt tgagcaaagc gcgtgacggt aatcgaaaaa gaagcctgct gggacaagca
    32761 ttccagcacg gcgcgttcct tttcaaaaga aagagagttg ggggcaatgt agaagacccg
    32821 cttgccagct gcaactagct cttctgcctc tcttgttaga atttctgtca aagaagttcg
    32881 aatatcagta taaagtaatt tcatctcagc ctcgttggaa tttttcatca ccctatatta
    32941 taccatgatt agcctcgtaa atctgttaaa atatttaggc catcctttct tttcttcatc
    33001 atctgctaaa tcttaaatac ttagctttac ttgtattaga tagaataagt ctggccactg
    33061 aaaatcatat aataaaaaag cctcggtaac aaggctttga gttttatgat tgtttcttag
    33121 gtacggaata cacttcaatg tgttgtccca gtgtcttaat gtcgacgggt agattgtctg
    33181 atttattgcc atcaacatcg gactctaatt cgatatcaga agaagtttta atattacgtg
    33241 cctttatata ttcaatattc ttgatagaat gattgaacta tagtaaattg aaactataat
    33301 agtacaccgt ggatgctaaa atatttctag aaattaattt gatttcccta atcaagctgt
    33361 tcgtatctta tttcaatcta ctattttcaa ttgactatat aaattgtcta agcgaaacaa
    33421 ccgataagaa ttggcacaaa agcgaccgta tttttgttac caatacagga aaaccagttc
    33481 atagttctat cttgagcaag tctctccagc gagcaaacga acgccttaaa aaaccaattc
    33541 ccaaacatct gtcccctcac atcttcagac acaccactat tagcatctta tcagaaaata
    33601 aaattccttt aaaaacaatc acggacaggg ttggtcattc cgactctgaa gtcactactt
    33661 ccatctacac ccacgtcaca aagaacatga aagatgaagc aatcaatgta ctggataaag
    33721 ttatgaaaaa gattttttaa aaagttttgc cccttttttg tcctctaaat acaaaaatag
    33781 cccttcggat aaaatccgag gggctagaaa cgttgttaaa tcaacggccg aacttttgaa
    33841 tttcatggtt cgggataaaa tagttcactg aactatttta ttttttaagg ttgtagaatg
    33901 atttcaatcc acgatattca gctacttcac caagttggtc ttcgatacga agcaattggt
    33961 tgtatttagc gatgcggtct gtacgtgaaa gtgaaccagt cttgatttgt cctgcgttag
    34021 ttgcaactgc gatatcagcg attgttgaat cttcagtttc acctgaacgg tgtgatacaa
    34081 cagcagtgta accagcttct ttagccattt cgatagcttc aaaagtttca gtaagagtac
    34141 cgatttggtt aactttgata aggattgagt tagcagcacc ttcttggata ccacgtgcaa
    34201 ggtagtcagt gtttgttacg aagaagtcgt caccaacaag ttgtactttc ttaccaagac
    34261 gttcagtaag agctttccaa ccatcccagt cgttttcatc cataccatct tcaatagtga
    34321 tgattgggta tttgttaacc aattcttcaa ggtagtcgat ttgttctgca gatgtacgaa
    34381 cagcagcacc ttcaccttca aatttagtgt agtcgtaaac tttacgttct ttatcgtaga
    34441 attctgatga agcacagtca aatccaataa atacgtcttt acctggtaca tatccagcag
    34501 cttcaatcgc agcaaggata gtttcaacac catcttcagt tccttcgaaa cgaggagcga
    34561 atccaccttc gtcacctacg gcagtttcca aaccacgtga tttaaggatt ttcttaagag
    34621 cgtggaagat ttcagcaccg taacgaaggg cttctttaaa tgttggcgca ccaactggca
    34681 agatcatgaa ctcttggaaa gcgattggag cgtcagagtg agaaccaccg ttgatgatgt
    34741 tcatcattgg agttggaaga actttagtgt tgaatccacc aaggtagctg taaagtggga
    34801 tttcaaggta gtcagcagca gcacgagcta cagcgataga cacaccgagg attgcattcg
    34861 cacccaattt acctttgtta ggagtaccgt caagtgcgat catagcacgg tcaatagctt
    34921 gttgatcacg tacatcgtag ccaatgatag cttcagcaat gatgttgttt acgttgtcaa
    34981 cagctttttg tgtaccaaga ccaccgtaac gagatttgtc accgtcgcga agttcaactg
    35041 cttcgtgttc accagtagaa gctcctgatg gaaccatacc acgtccgaaa gcacctgatt
    35101 cagtgtaaac ttctacttca agtgttgggt taccgcgtga gtctaggact tcgcgagcgt
    35161 aaacatcagt aataattgac attttttact ctccttatga gttaaatttt ttacacctct
    35221 ataatacctt aaaacccctc ctttttcaag aaaaaacgtt atctttgtgc aacttttcct
    35281 taactttata aagtaatcgc tttcttttgt ctgttttatt ctaactttta tgatatactg
    35341 ttttcatgac agatttatca aaacaattac ttgaaaaagc tcatggtggg ttaaaaataa
    35401 atccggatga gcaaagacgc tatcttggta cttttgagga aagagttctt ggatatgtag
    35461 atattgacac agcaaatagc cctcagttag aaaaaggctt tttatttatt ttagaaaacc
    35521 ttcaggaaaa agcagagcca ctatttgtga agatttcacc aactatcgaa tttgataagc
    35581 aagttttcta cttaaaagaa gcaaaagaaa ctgatagtca agccaccata gtatctgaag
    35641 agcatattac ttctcctttt ggcctggtta ttcatagcaa tgcaccagtt caagtagaag
    35701 aaaaagacct tcgacttgct tttccaaaac tttgggaagt taaaaaggaa gaaccagcca
    35761 aaacatcctt atggaagaaa tggtttagct aaatcttgca catatttaat aagtgcccaa
    35821 tattggcagc cgtgcgctcc agatagagac tggcattttt caaactatct tctaaaggtt
    35881 cacttttctc caaaatagaa aagacagctt ggatattttc aaatggtagg ggaggtaaat
    35941 cttcagcaag actaccgcaa atagcaataa caggaactcc aacaggggtt ctttttgcaa
    36001 cacctatagg cgctttccca gcaaagcttt gactatcaag tcttccttct ccaacaacaa
    36061 ccaagtcagc atctgaaact ttcttatcaa agttgattaa gtccaagcag gtatcaattc
    36121 cagacacgat acttgcctga gcaaaggcac acaaaccacc agcaaggcct ccacctgctc
    36181 ctgctccttt aatttctaat gttgcaggtg agaatttttc ataaaaatct tggatcgcct
    36241 gatctacgac tgcaaacata gtcggatgta gacctttttg attgccaaaa gtgtaagtcg
    36301 caccttgatg accacataag ggactcacga catctgctag aatatgaatt tgaacacctt
    36361 caggaatttt atagcaattt tctgttgaaa cagaagctaa gtctaataag gattgaccgg
    36421 aagcaggcaa gacatttcca tccctatcat aaaattgata acctaaacca gcagcaatcc
    36481 ccagtcctcc atcattactg gccgtgccac caacaccgat ataaatatct ttaatccctt
    36541 tagaaatgag atggagaatc aactctccaa taccataagt ttggatttga agtggatttc
    36601 gtttctctag cggaattttt ccaagaccaa ccaagtcagc tacttcaaat agtgccagtt
    36661 cccctttttg aaaatagcgc atggcttctt tttgtccaaa agggtctgtc attttaggtc
    36721 aagagaatgt cggatagcat ctacagtacc ttctccccca tcaccaacag ggcagaggag
    36781 atattctaca tctgctatcg attgttggaa gcctcttttt attgcttcag ctacctgttg
    36841 agctgtcaaa ctttccttaa acgaatctgg tgcaattaca atcttcatat tttccctcat
    36901 tctaaacagt caatcaaagg aagaacttct aaaaaatccc tcttgtcaac atgatgtggt
    36961 atttcttttt tgagcacttc tttggcacaa aaggcgattc ctaactccgc cgacttcaac
    37021 attaatagat tattgacccc atcaccgatt gccaccgttc tttctttaga aagttttagt
    37081 ttctttctcc atttttccag agtctctttt ttgacctggg gacttataat ttgttcaact
    37141 aattttcctg ttaaaagacc ttctttgact tcaagctggt tggcagtgaa ataggcaata
    37201 ccaagggatt ttgctaatct ctccaactat tggtatccac cagacaccac acaccagacc
    37261 aactaggatg ccattctttt ggagaataga gatgaactct gggacattta gcgatagatg
    37321 aattgagttg aagacgttat caaagaccaa aataggaaga ccttccaaca aggacactct
    37381 ttttcttaaa ctgctttcaa agaccaactc tcctcgcatt gcccgacttg taatctgcga
    37441 aatttccgcc tcatgacctg cctctctccc taaaagatca atcacttctt ctaggattaa
    37501 ggttccatct acatccaaaa cacacaagcc ttttacttga gacatcagtt ctcctctcta
    37561 aacagcctaa aaatcgtatg aagtcatcat acgattttat ctattaatta actaaactat
    37621 ggtacaagtc aaggtatgac ttgcaggctg tatcccatga gaagtcactc tccatagctt
    37681 gtttttgtag gtttctccaa atgtctggat ggtttctata caagtccaat gctgtttgga
    37741 aagtccaatt taaccaataa ggagatagat tgtcaaagct aaagccagta ccgcttcctt
    37801 cgattggatt gaaagcgcga actgtatctc gcaagcctcc aacttcatgg accaatggca
    37861 aggttccata acgcatagcc atcatttgag acaagccaca cggttcaaaa cgacttggca
    37921 tgaggaagag gtcacaagca gcgtagattt cctgagcaag tttgacatca aaagtgatat
    37981 ttgttgatag cttgtctggg taaatctgag caaaccatga gaaagctcct tcaaaggctg
    38041 gatcgccagt tcccaaaaga acaatctgaa catcttcttg caagatatgg tgaagacttt
    38101 cgaccaccac atcaaaacct ttttgacgtg tcaaacgaga aacaattccc accagtggaa
    38161 cgtctgctct aacaggcaag ccaactcttt cttgcaattt tgccttattt ttggctttcc
    38221 cagacaaatc ttcctgattg aaatgatagt ctaaaagagc atccgtctga ggattataaa
    38281 gatcagcatc aatcccattc acgataccag atactttacc agactccatt ttaagaatct
    38341 gatccaaatt acatccaaac tgactagtca taatttcatg agcatagcta ggtgaaacgg
    38401 ttgaaacacg gttcgcatag agaatacctg ccttcatcca gttcagacag ttgttccatc
    38461 gaagggtgcc atcagcgtaa cgttcaaagc caactccaaa caaatcaccc aacattcctt
    38521 ctgaaaattg tccttggaat tctaaattat gaatggttaa aactgtttca atgtcctcat
    38581 aggcttgaat ccaacggtat ttttccttca acaagaaagg aatcatagct gtatggtagt
    38641 catgaacatg gagaagatca ggaataaagt caatcctttc catagcctca atggcagcca
    38701 gttggaaaaa ggcaaagcgt tctccgtcat caaaatcacc gtaaacatga ccacggaaga
    38761 aataatattg attgtcaata aagtagaagg ttacaccatt taatactgtt ttcttaattc
    38821 cacaatactg tctgcgccaa ccaacgctca cctcaaaatg aagtacatct tcaatctgat
    38881 ttccaaattt agcctctacc atatcatagt agggtaaaat cactgcaact tcgtgcccag
    38941 cttttaccag tgattttgga agagcgccaa tgacgtctcc caaaccacct gtttttgaaa
    39001 agggtgcacc ctctgctgct acaaataaaa ttttcatgaa tgaatatcct ctgttacttt
    39061 agcacctttc ttaaccacaa ctggatgttc tgcagttcct cgaatcacaa caccatgctc
    39121 aacttcaacc cctttgtcca agatagcata ttcgacctga gccccttctc caataacaac
    39181 acgagggaag agcaggctat ctttaaccaa gctatcctta tggacatgaa tattacgtga
    39241 tagaacagaa ttagctactt gaccttcaat aatactacca gaggcaaact gagaagtgct
    39301 taccttagat gtattagcat agtaagttgg ctcttcgttt ttgacctttg tataaatctt
    39361 ttggtttggt gagaaaagag aatagaattt ttgtgattca agcatatcga tattcgcttg
    39421 ataataagat ttaacagagt gaatattggc tagatagccc gtgtactcgt aggcgaaagc
    39481 tccctctttt acagccaaat cccgtaaaac atagcgaaat ttctctggat gttctttttt
    39541 agcttcttct tccaagtgtt caatcaacca aggtgtatca acgacaaaga tatctgtaga
    39601 catattgaac gtttcagctg ttgacttgct atcaaagagt ttatgagaaa gaacatggtc
    39661 tgtttcatct acatccaaga ttgcatttac ttctgaaata tctttcttag ctagtttttt
    39721 ataaactaca gtgataggct cttttgttgt actatgtagg tggaaaactt ggttcaaatc
    39781 aatgttaata agaacatcgc agttgagggc aaccgtttgg tttgagccag aacgtttcaa
    39841 ataagtaaga agctgttggt agtattcttt tccaactgta ctactttcta cacgggtatt
    39901 gtaaattcct agatagtaat gactaagaag ggttgataag ccccactcgc gtcctgaacg
    39961 aatatggtca aatactgagc tgatattatc ctgctggaaa ataccaaaga cactacgaac
    40021 acctgcatta gcaaggcttg aaagtgggaa gtcaatcaaa cgatatttcc caccaaatgg
    40081 caaacttgct actggacgat ggtctgtcaa tgtcgacata ttgtgaaaac caactgtatt
    40141 tcctaaaatg gcagaatatt tatcaatctt catctgttgc tacccccact acttcattat
    40201 atcctacaac ttgtacttca tctgttccat caatttcgac accgtcagaa ataatcgcac
    40261 cttcaccaat aatggcacgt ttaatcttag ctccttgacc aatgatagct ccactcatga
    40321 taactgaatc aaggacttcc gctccttcgc gaacttgcgc gcctgttgaa aggatagaat
    40381 gtttaacagt tccatcaacg aaacatccgt ctacaactaa tgagtcttcc acatgagcat
    40441 ttgccccgag gaagtttggt ggtgaaatca agtttcttga gtaaatcttc cattgacggt
    40501 tacgactatc caaggcattt tctggagaaa tatactccat gttcgcttcc caaagtgact
    40561 caatagtacc aacatctttc caataaccac taaattcgta agcataaaca ctttcacctg
    40621 actcaaggta atttggaatg acatttttac caaagtctga catgccaacc ttgctctttt
    40681 cagcagcgac taacatatta cgaaggcgtt gccaatcaaa aatgtagatt cccatagaag
    40741 cttttgtaga tttaggttga gctggttttt cttcaaattc aacaatacga ttgttagcat
    40801 ctgtgttcat gataccaaaa cggcttgctt ctttaagagg gacgtctaaa actgctactg
    40861 tcaagctggc attattatcc ttatgagact ggagcatatc atcatagtcc attttgtaga
    40921 tgtggtcccc agacaaaatc aagacatact caggattgac actgtcgata tagtcgatat
    40981 tttggtaaat agcgtgacta gttccctcaa accaacgatt tccttcactt gcagaataag
    41041 gttgaagaat agagacgcct gaattaatac cgtctagtcc ccagcttgaa ccattcccaa
    41101 tatggttgtt gagagcaagt ggttgatact gtgtaacgac cccaacatta tgaatccctg
    41161 agttggcaca gtttgatagg gcaaagtcaa tgatacggta gcgcccacca aattgcacag
    41221 ctggttttgc gatgctttga gtgagtttac cgagacgagt tccttgccca ccagcaagaa
    41281 tcaaagctaa catttcattt ttcattttct actccttttt ggtttttatt tgtgacggtt
    41341 ttagtagatt tcaagcgacg tttgattttc catacacttg ctcccatagc cggtagagta
    41401 aaggttaagg tctgctcata atctttccat aggccttctt gcgtttgaac agtttgatta
    41461 tgttctttcc aaacgcctcc ccactcttcc aactcagtat tccatacttc ttcgtaaatt
    41521 cctgcaacgg gtagtccgat tgtaaaatct ttccgctcaa caggtaccat gttaaagata
    41581 cagactaaca tttctccctt tttaccctta cgaataaagg aaagaacact ctggtctcga
    41641 ttatccgcat caatgatttc aataccatca tagctggtat cgatttccca cagacagcga
    41701 tgatctttgt aaaactggtt tagctgagaa gtgaaatact tcatcttagc attcattggg
    41761 tcttctaggt tagaccattc caactgttct tcagatttcc attctaggaa ttgaccgtat
    41821 tcgctaccca tgaagagcaa tttcttacca gggtgacaaa tttggtacgt atagagattg
    41881 cgcaagcttg cgaattgatt gtaacgatct ccccacatct tatgcatcat actcttcttg
    41941 ccatgaacca cttcatcgtg cgagaatggc aagagataat tctccttgaa aacatacata
    42001 aagctgaaag tcaccaggtt aaagtcatat ttacgataaa tcggatcttc ttcgtagaaa
    42061 cggaggatat cattcatcca gcccatgttc catttgtagt caaatcctag accaccaatc
    42121 tctttcattc ccgtaatctt ggtcgcagac gaactttctt ctgcaatcat catcacatct
    42181 ggatattcta acttaataac ttcattcaag cgttgaagaa aataataacc ttcatagttg
    42241 agatttccgc catctttatt aggtgtccat ggagcattat catagtccaa atagagcatg
    42301 ttgctaacag catccacacg aataccatcc aaatgataga catcaatcca atgcttaatg
    42361 caagaaatta agaaggactg gacttcattt tttccaaggt caaaattaag ggcaccccaa
    42421 ccatggttat gagccttatt atggtcttgg tattcaaaag tcggtgtccc atcataatag
    42481 gctaaggcat catcgttgat ggtaaagtga cctggtaccc agtccacaat aaccccaata
    42541 ttatgggtat gacactcctc gacaaaatct tgaaactcct ctggtctgcc ataagcatgc
    42601 tctaaagcga agtaacccat aagctgatac ccccaactca agcccaaagg atgggacatc
    42661 aagggcataa actcaatatg agtatagttc atttcaacga gataaggaat gagttcatcc
    42721 ttgagctggg caaaactata aggactgcca tcagaatttc ttttccatga tccagcgtga
    42781 acttcataaa tattgacagg acgctcttca aagccccaac gttttcttcg tgccagccaa
    42841 agtccatcct tccatttctt ctcaggaagc tctgttaaga ttgcccctgt tcctggacga
    42901 gcctcatacc tgacagcaaa agggtcaatc ttcatcagtt gatgaccatt ttgacgtgtg
    42961 acatgatatt tgtaaatatg cccttcttga gccatattgg taaagacttc ccagacccca
    43021 aaatcatttc ttaccattgg aatctgattt tcaatccagt tggtaaaatc accaaccaag
    43081 tgaacagcct gagcattagg tgcccaaaca cggaaggtat agccatgctc tccatttagt
    43141 tcttccctat gtgctcctag ataatgttgg agataaaaat tttcacccgt cataaaggtt
    43201 tttaatgctt ctctattatc catatactcc ccttctcctg taagcgtttt ctatgttttt
    43261 attatactac ctttttagag aagattcaag taaattacta tacttcttta attattttga
    43321 aaatctacaa caagttcact tactcgttca attgtaaatc aatatttttt caaaaaattg
    43381 cgaaaacgcc tttctttttc ta
//
LOCUS       DBERXF010000015        43143 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.15, whole genome shotgun sequence.
ACCESSION   DBERXF010000015 DBERXF010000000
VERSION     DBERXF010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 43143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43143
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.15"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            6..76
                     /locus_tag="ACL8JK_000914"
     tRNA            6..76
                     /locus_tag="ACL8JK_000914"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38..40,aa:Gly,seq:tcc)
     gene            112..185
                     /locus_tag="ACL8JK_000915"
     tRNA            112..185
                     /locus_tag="ACL8JK_000915"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:146..148,aa:Ile,seq:gat)
     gene            192..279
                     /locus_tag="ACL8JK_000916"
     tRNA            192..279
                     /locus_tag="ACL8JK_000916"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:226..228,aa:Ser,seq:gct)
     gene            complement(405..1340)
                     /gene="birA"
                     /locus_tag="ACL8JK_000917"
     CDS             complement(405..1340)
                     /gene="birA"
                     /locus_tag="ACL8JK_000917"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HGS1785820.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1337..2197)
                     /locus_tag="ACL8JK_000918"
     CDS             complement(1337..2197)
                     /locus_tag="ACL8JK_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGS1785821.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2305..4467
                     /locus_tag="ACL8JK_000919"
     CDS             2305..4467
                     /locus_tag="ACL8JK_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGS1785822.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4559..5818
                     /locus_tag="ACL8JK_000920"
     CDS             4559..5818
                     /locus_tag="ACL8JK_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS1785823.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5832..6698
                     /locus_tag="ACL8JK_000921"
     CDS             5832..6698
                     /locus_tag="ACL8JK_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1785824.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAAFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            6712..7545
                     /locus_tag="ACL8JK_000922"
     CDS             6712..7545
                     /locus_tag="ACL8JK_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1785825.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAIMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7856..9298
                     /gene="gtfA"
                     /locus_tag="ACL8JK_000923"
     CDS             7856..9298
                     /gene="gtfA"
                     /locus_tag="ACL8JK_000923"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HGS1785826.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYALNEFYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9436..10629
                     /locus_tag="ACL8JK_000924"
     CDS             9436..10629
                     /locus_tag="ACL8JK_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGS1785827.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11314..13293
                     /locus_tag="ACL8JK_000925"
     CDS             11314..13293
                     /locus_tag="ACL8JK_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1785828.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13360..14856
                     /locus_tag="ACL8JK_000926"
     CDS             13360..14856
                     /locus_tag="ACL8JK_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1785829.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14856..15782
                     /gene="oppC"
                     /locus_tag="ACL8JK_000927"
     CDS             14856..15782
                     /gene="oppC"
                     /locus_tag="ACL8JK_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HGS1785830.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSIRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15791..16858
                     /locus_tag="ACL8JK_000928"
     CDS             15791..16858
                     /locus_tag="ACL8JK_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785831.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIVQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16869..17795
                     /locus_tag="ACL8JK_000929"
     CDS             16869..17795
                     /locus_tag="ACL8JK_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1785832.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            18285..19223
                     /locus_tag="ACL8JK_000930"
                     /pseudo
     CDS             18285..19223
                     /locus_tag="ACL8JK_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate binding protein"
     gene            19235..20124
                     /locus_tag="ACL8JK_000931"
                     /pseudo
     CDS             19235..20124
                     /locus_tag="ACL8JK_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            20137..20940
                     /locus_tag="ACL8JK_000932"
     CDS             20137..20940
                     /locus_tag="ACL8JK_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785833.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSMDEGDLLLAGKSIKNLSVRKRAKDIARVFQAPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQLTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLR"
     gene            complement(20972..21682)
                     /gene="treR"
                     /locus_tag="ACL8JK_000933"
     CDS             complement(20972..21682)
                     /gene="treR"
                     /locus_tag="ACL8JK_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGS1785834.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21867..23834
                     /gene="treP"
                     /locus_tag="ACL8JK_000934"
     CDS             21867..23834
                     /gene="treP"
                     /locus_tag="ACL8JK_000934"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGS1785835.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            24012..25637
                     /gene="treC"
                     /locus_tag="ACL8JK_000935"
     CDS             24012..25637
                     /gene="treC"
                     /locus_tag="ACL8JK_000935"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGS1785836.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25893..26141
                     /locus_tag="ACL8JK_000936"
     CDS             25893..26141
                     /locus_tag="ACL8JK_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGS1785837.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26348..27142
                     /gene="racE"
                     /locus_tag="ACL8JK_000937"
     CDS             26348..27142
                     /gene="racE"
                     /locus_tag="ACL8JK_000937"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGS1785838.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27139..28110
                     /locus_tag="ACL8JK_000938"
     CDS             27139..28110
                     /locus_tag="ACL8JK_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HGS1785839.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            28086..28607
                     /locus_tag="ACL8JK_000939"
     CDS             28086..28607
                     /locus_tag="ACL8JK_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGS1785840.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28604..29065
                     /gene="cbpB"
                     /locus_tag="ACL8JK_000940"
     CDS             28604..29065
                     /gene="cbpB"
                     /locus_tag="ACL8JK_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGS1785841.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            29062..29796
                     /gene="xerD"
                     /locus_tag="ACL8JK_000941"
     CDS             29062..29796
                     /gene="xerD"
                     /locus_tag="ACL8JK_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGS1785842.1"
                     /translation="MRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETSLK
                     IYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEILYL
                     DSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVTIP
                     TALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFILRQ
                     IENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29796..30524
                     /locus_tag="ACL8JK_000942"
     CDS             29796..30524
                     /locus_tag="ACL8JK_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGS1785843.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30543..31112
                     /gene="scpB"
                     /locus_tag="ACL8JK_000943"
     CDS             30543..31112
                     /gene="scpB"
                     /locus_tag="ACL8JK_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGS1785844.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31099..31821
                     /locus_tag="ACL8JK_000944"
     CDS             31099..31821
                     /locus_tag="ACL8JK_000944"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGS1785845.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31821..32063
                     /gene="yidD"
                     /locus_tag="ACL8JK_000945"
     CDS             31821..32063
                     /gene="yidD"
                     /locus_tag="ACL8JK_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGS1785846.1"
                     /translation="MKRILIALVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPIPDHFSLKRNQEGE"
     gene            complement(32288..33253)
                     /locus_tag="ACL8JK_000946"
     CDS             complement(32288..33253)
                     /locus_tag="ACL8JK_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1785847.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEITI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETSTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33349..34101)
                     /locus_tag="ACL8JK_000947"
     CDS             complement(33349..34101)
                     /locus_tag="ACL8JK_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785848.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            complement(34098..35054)
                     /locus_tag="ACL8JK_000948"
     CDS             complement(34098..35054)
                     /locus_tag="ACL8JK_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGS1785849.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFVLLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFSFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(35044..36003)
                     /locus_tag="ACL8JK_000949"
     CDS             complement(35044..36003)
                     /locus_tag="ACL8JK_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1785850.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGDLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36300..36410)
                     /locus_tag="ACL8JK_000950"
     CDS             complement(36300..36410)
                     /locus_tag="ACL8JK_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HGS1785851.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            complement(36426..37127)
                     /locus_tag="ACL8JK_000951"
     CDS             complement(36426..37127)
                     /locus_tag="ACL8JK_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS1785852.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SHASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTTNVAGMNQV
                     LKVLSEVGIQKIMFSSTASLCGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37528..38592
                     /gene="pepA"
                     /locus_tag="ACL8JK_000952"
     CDS             37528..38592
                     /gene="pepA"
                     /locus_tag="ACL8JK_000952"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGS1785853.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38614..38910
                     /locus_tag="ACL8JK_000953"
     CDS             38614..38910
                     /locus_tag="ACL8JK_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGS1785854.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            39592..40035
                     /locus_tag="ACL8JK_000954"
     CDS             39592..40035
                     /locus_tag="ACL8JK_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGS1785855.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            40039..40803
                     /locus_tag="ACL8JK_000955"
     CDS             40039..40803
                     /locus_tag="ACL8JK_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HGS1785856.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            40818..41546
                     /locus_tag="ACL8JK_000956"
     CDS             40818..41546
                     /locus_tag="ACL8JK_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1785857.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            41539..43059
                     /locus_tag="ACL8JK_000957"
     CDS             41539..43059
                     /locus_tag="ACL8JK_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGS1785858.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENVIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
BASE COUNT        12494 a         8002 c         9687 g        12960 t
ORIGIN      
        1 tttatgcggg tgtagtttag tggtaaaact acagccttcc aagctgttgt cgcgagttcg
       61 attctcgtca cccgctttga actttgttca aattaccaag ttttttaact tgggcgcgta
      121 gctcaggtgg ttagagcgca cgcctgataa gcgtgaggtc ggtggttcga gtccactcgt
      181 gcccattaat tggagaatta ctcaagaggc tgaagaggac ggtttgctaa atcgttaggt
      241 cgggtaactg gcgcaagggt tcgaatccct tattctccgt tttaatgaga gtttgtaact
      301 ctctttttta tttttagagc caataaaact tcagatccgt aaaacttaat tgaattacta
      361 atctgaagtt atttttatat cgtttatatt ataattgtgt tattttactt ccaactattg
      421 agagaaattt cgccactatt tagccagatt tcttttccgt tatcacattg aactaaaagt
      481 tttccatttt ctgagatgtc tttagcaagt cccttgtagt ctttttgctc tagtgtgaaa
      541 gtgacttctt ttcctagaat gaatgactgt tttttgtata ggtataatag ctcttctgct
      601 ggtgtttcga agaaagcacg ccagatttct atgatcaatt cattccttgt tataggagct
      661 gtagctttaa ataagctggc agctttttct tttaattcct gagggaagtc tttaatagtg
      721 aaattgatac ctactccaat aatgatatct gtgactaagc cagtttctac agaggtcatt
      781 gcttcagtaa ggattcctcc aattttatga ttgtttagat agatatcatt gacccatttt
      841 atgtcgacat ctattaaagt taggttctta atggctttgt agacagctcc agctacaagt
      901 agtgtgtagg atggtaattt gtcatagggg agatttggtt taagatggag tgtcatataa
      961 ataccacctt gtggtgagta gaaggaacgt tgaaaacggc ctcggcctgc tgtttgatag
     1021 gaagctagat agagggtatt tgcttcatgg cctaaatcaa ttgcttcttt tgcatctagt
     1081 tgtgttgatt ttgtttcggg tttaaagctg actttaattg gaagattttc ttctagaatc
     1141 tctggaagaa taaggtcacc attcatcagt ttatatcctc tatttttgat actatcaatt
     1201 tcaatgcctt cttgttctag tcgcttgatg gctttccaaa ttgctgttcg gcttagggat
     1261 agtttttctg cgattttttc tccgctgata tagtcggttt ctttagatag gatttggtag
     1321 acagcttggt aggatttcat aatgttgcct ttcttactag ttggtattga gagtattctt
     1381 ttcttgtatg acttggagtc tgattaaagt attgtttata agctttcgaa aaatggagtg
     1441 gatctgaaaa acctaccgag tatgcaatta ccttgatgga ctcttgggta ttttcgagaa
     1501 gttgtctagc tcggtgcatt cgaacgtaga gtaggtattc tttgggtgat aaggtattaa
     1561 attctttgaa tacgcttgat aagtagcttc tgtgaacgga tagttctttt gctaaatctt
     1621 gaattgtaag tgattgagga tagtggctat caattaatcg tttgcattca agatagagtt
     1681 ggtgggttga tgaaatattc ttttttttct gattgggagc aatagttccc agatgaaaca
     1741 tcagttcatg aagttgtccc atgatatgga gttgagctaa ttcacttgat tttgtaatct
     1801 gagcgaagcg gacaatgtct gagatgagtt ttgcagtagt ctgggtatga caagtttcag
     1861 attggatgag ataggattga tcagaaattt gggaaagagc aaaataatca ggggctttcc
     1921 ctccagtgat tcctaaccag tagtaggccc aaggttcttt actatctgct tgataaaagg
     1981 ttagttcctc tggttttaat agaaagaaat ctccttcttt taaatcaaca attttaccct
     2041 tgtaatgaaa ttttccttgt cctttagtaa tgtaatgtag aacgtatgta tcacgaatgg
     2101 ctggaccaaa agagtaatta ggtgtgcatt cctcatatcc ataaaagctt agggcaaggt
     2161 cgattgttcc agtctggtat tctgaaaaaa ctaacatgtg ctacctccta cctaacattt
     2221 taccatattc ttgagacatt tttctatttt ggaaagcgat ttcaggtgat aaaatataat
     2281 caataaagtg atgaggtgaa gtaaatggga gttaggatag agaataatct attttatgtt
     2341 gagagtaaaa atctaagttt gattattgaa aatcgaaatg gctacttact tttgaaacat
     2401 ttaggaaaga ctattaagaa ctataaaggt tccaatagtg tttatgaacg agaccatgcc
     2461 ttttcaggaa atccaacggc tactaatcga acctttagtt tagatactca gcgacagatt
     2521 tttggacaac atggcttagg agattttagg aaaccaacca tacaggttca gcatagtgta
     2581 actgaagtaa cagactttcg atttgtagaa gcaaagattt taaaaggtca gaatggtcca
     2641 cagggcttac cttctccaca tagcatggac gatacagaga ctcttgtctt aatgttagaa
     2701 gattctaagg ctcaacttag tctgactttg tattatacta cttttaataa tgatgcgact
     2761 attgctagct acagtaaatt agataataat agtaatcagg aagttgtcat ccataaagat
     2821 ttttctttta tggctgattt tccagctgca gattacgaaa tagtaactct gcagggtgct
     2881 tatgctcgtg aaaagactgt tagacgtcaa caggtagaac aaggaatctt ttcgattagc
     2941 tcaaaccgag gtgcttctgg tcatgctcaa acaccagctc ttctactatg cgaacaagga
     3001 gtcacagagg atgctgggaa tgtgtttgct attcaactaa tgtatagtgg caactttgaa
     3061 gcttttgttc aaaaaaatca attgaatgaa gttcgggtgg ctattggcat taatccagaa
     3121 aacttttctt ggaagttagc ccctgaggaa tactttgaaa caccggtagc tttagtgact
     3181 cattcagatc agggattaac tggtattagt catgaaagtc agaattttgt actgaagcac
     3241 attatgctaa gtgaattttc taaaaaagaa cgtccaattc taatcaataa ctgggaagct
     3301 acttactttg actttcagag agaaaaactg ttagagttag cagatgaagc taagaaagtt
     3361 ggcattgaac tttttgtatt agatgatggt tggtttggca atcgttttga tgataatcgt
     3421 gctttaggtg attgggttgt taatgaggaa aaactgggtg gaagtctaga aagtctgatt
     3481 tcagctatcc atgaaagagg tttgcagttt ggactttggt tagaacccga aatgatttct
     3541 gtagatagtg atttgtatcg tcaacatcct gactgggcta ttcaggttcc tgattatgag
     3601 catacttatt ctcggaatca attagtactt aatcttgcca atcctcaggt agtagaatac
     3661 ttgaaaagtg tcttagatca actcctatct tatcatgaga ttgattacat taaatgggat
     3721 atgaaccgca atatcactaa gctagggaat ggattaactt atctagagac acagatgcaa
     3781 tctcatcagt acatgctggg actttacgaa ctcgtttctt atctgacaga gaagcacagc
     3841 catattctct ttgagtcctg ctctggtggt ggtggacgaa atgatcttgg tatgatacgc
     3901 tatttcccac aagtctgggc tagtgataat actgatgcca ttgcacgttt accaattcaa
     3961 tacggttcat cctatctcta tccaaccatt tctatggggg ctcatgtgtc agcagtaccg
     4021 aatcatcaga tgggacgaat gacaccatta gaaacacgtg gccatgtagc aatgatggga
     4081 aatttgggct atgagcttga tttgacaaat ttatcagatg aagagaaagc tacgattgct
     4141 aatcaggtga acttgtataa agaattacga ccagtagttc agttaggaca gcagtataga
     4201 ctaattaatc ctgatactgc atccaatgaa gcagctgtac aatttaatta cggaaatcaa
     4261 acgattgtaa cctacgttcg cgttttatct gttgtagaga ccatggaaac aactttaaaa
     4321 ttaaaagatt tggatgaaga gggactatat aaattacagg aaaatggcga agtttactca
     4381 ggtgcagaac taatgtatgc gggcttaact gttatcttat cccaaggaga ttttttgagt
     4441 agacagtata tttttagaaa actatgatat gtactgaccc caaaagttag atttattctg
     4501 tctaactttt ggggtgcagt tcaataaggg tgtataaatt tataaaggag gctttctaat
     4561 ggaatggtat aaaaaaatcg gacttcttgc aactacaggt ttagctttgt ttgggctcgg
     4621 cgcttgctcc aactatggta aatctgcgga tggcacagtg accatcgagt atttcaacca
     4681 gaaaaaagaa atgaccaaaa ccttggaaga aatcactcgt gattttgaga aggaaaaccc
     4741 taagatcaag gtcaaagtcg tcaatgtacc aaatgctggt gaagtattga agacacgcgt
     4801 tctcgcagga gatgtgcctg atgtggtcaa tatttaccca cagtccatcg aactgcaaga
     4861 atgggcaaaa gcaggtgttt ttgaagattt gagcaacaaa gactacctga aacgcgtgaa
     4921 aaatggctac gctgaaaaat atgctgtaaa cgaaaaagtt tacaacgttc cttttacagc
     4981 taatgcttat ggaatttact acaacaaaga taaattcgaa gaactgggct tgaaggttcc
     5041 tgaaacctgg gatgaatttg aacagttagt caaagatatc gttgctaaag gacaaacacc
     5101 atttggaatt gcaggtgcag atgcttggac actcaatggt tacaatcaat tagcctttgc
     5161 gacagcaaca ggtggaggaa aagaagcaaa tcaatacctt cgttattctc aaccaaatgc
     5221 cattaaattg tcggatccga ttatgaaaga tgatatcaag gtcatggaca tccttcgcat
     5281 caatggctct aagcaaaaga actgggaagg tgctggctat accgatgtta tcggagcctt
     5341 cgcacgtggg gatgtcctca tgacaccaaa tgggtcttgg gcgatcacag cgattaatga
     5401 acaaaaaccg aactttaaga ttgggacctt catgattcca ggaaaagaaa aaggacaaag
     5461 cttaaccgtt ggtgcgggag acttggcatg gtctatctca gccaccacca aacatccaaa
     5521 agaagccaat gcctttgtgg aatatatgac ccgtccagaa gtcatgcaaa aatactacga
     5581 tgtggacgga tctccaacag cgatcgaagg ggtcaaacaa gcaggagaag attcaccgct
     5641 tgctggtatg accgaatatg cctttacgga tcgtcacttg gtctggttgc aacaatactg
     5701 gaccagtgaa gcagacttcc ataccttgac catgaactat gtcttgaccg gtgataaaca
     5761 aggcatggtc aatgatttga atgccttctt taacccgatg aaagcggatg tggattagga
     5821 gtagagagac tatgaaaaaa gtattacaaa aatattgggc atgggctttt gtggtcatcc
     5881 ccctcttgtt acaagcaatt ttcttctatg tgccgatgtt tcaaggagcc ttttacagtt
     5941 ttaccaactg gacaggattg acttataact acaaatttgt cggcttaaac aactttaagc
     6001 tcctcttcat ggatccaaaa ttcatgaatg cgattggctt taccgcaatc attacgattg
     6061 ccatggtggt tggtgagatt gcactcggga tcttcattgc gcgtgtcttg aactctaaaa
     6121 tcaaaggcca aaccttcttc cgtgcttggt tcttcttccc agctgtttta tctggtttga
     6181 cagtggcttt gatcttcaag caagtcttca actacggtct tccagcgatt gggaatgccc
     6241 ttcatattga atttctccaa accagtcttt tagggactaa gtggggagca atctttgcgg
     6301 ctgcctttgt ccttctttgg caaggggtgg ctatgcccat catcatcttc ctagctggtt
     6361 tgcaatctat tccaactgag attacagagg cagcaaggat tgatggtgcg actagcaagc
     6421 aagttttctg gaacattgaa ttgccttact tgctaccaag tgtctctatg gtctttatcc
     6481 tagccctaaa aggtgggctg actgcctttg accaagtctt tgccatgacc ggtggtggtc
     6541 caaacaatgc cacaacctca cttgggctct tggtttataa ctatgccttt aaaaacaacc
     6601 aattcggtta tgccaatgcc attgccgtaa tcttgttcct cttaattgta gtgatttcga
     6661 tcatccaatt gagagtatct aagaaatttg aaatttaaga ggagaagcat gatgaaacaa
     6721 gatgaaagaa aagccctgat tggcaaatac attctattga ttctaggatc ggttctgatt
     6781 ttagtgccgc tccttgctac cctctttagt tccttcaaac ccactaagga tattgtagat
     6841 aatttctttg gctttccaac caacttcaca tgggacaact ttagccgtct cttagctgat
     6901 gggattggag gctattattg gaactctgtc gtcatcactg tcttgtcttt acttgcaata
     6961 atgatcttta tccctatggc agcctactcc atcgctcgca atatgagtaa aagaaaagcc
     7021 tttaccatca tgtataccct cttaatcctc ggaatcttcg tacctttcca agtcatcatg
     7081 attccgatta cggttatgat gagtaaactc ggtttggcta atacctttgg tttgatcttg
     7141 ctctacttga cctatgcgat tccacagacc ctctttctct atgttggcta tatcaaaatc
     7201 tcgattccag aaagtctgga tgaagcagca gagatcgatg gggctaatca atttacaacc
     7261 tatttccgca tcatcttccc aatgatgaaa ccgatgcatg cgacaaccat gatcatcaat
     7321 gccctttggt tctggaatga cttcatgttg ccactccttg tcttgaaccg ggattccaaa
     7381 atgtggactc tgcctttgtt ccaatacaac tacgcaggcc aatatttcaa cgactacgga
     7441 ccaagctttg cctcttacgt ggtcggcatt atcagtatca ccattgtcta tctcttcttc
     7501 caacgccata tcatttcagg aatgagcaac ggggcagtga agtaatactc aatgaaaatc
     7561 aaagagcaaa ctaggaagct agccgcaggc tgtacttgag tacggtaagg cgacgctgac
     7621 gtggtttgaa gagattttcg aagagtataa gaagagctca tggaatctat agtctttgac
     7681 acagaggaag agttcagctt gttgataatt ctatgtagaa aacaagaaag tagtactttg
     7741 tttatcacag tctatattag tacgagtttg atgataaata gagatttaaa atgaatttta
     7801 tttatgaagc cagatcatat gagacttggc ttcaattaga aaaaggagag taatgatgcc
     7861 aattcaaaat aaaaccatgt tgattaccta ttctgatagc cttggaaata atcttaaaga
     7921 cttatatgat aatttggaag agcattttgg agatgctatt ggaggagttc accttttacc
     7981 atttttccca tcaacaggtg atcgtggatt tgcgccagtt gactacgacg aagtggactc
     8041 agcttttggt gattgggagg atgttaagcg tttaggtgag agatattatc ttatgtttga
     8101 ttttatgatt aatcatattt ctcgtcaatc caagtattat aaggactatc aagaaaaaca
     8161 tgaagccagt gaatttaaag atctcttttt aaactgggat aagttttggc cagaaaaccg
     8221 tccgacacag tctgatgtag atttaattta caagcgtaag gatcgtgcac caaagcaaga
     8281 gattgtgttt gaagatggtt cagtggaaca tttgtggaat acctttggtg aggagcagat
     8341 tgatcttgat gtgaccaaag aagtaactat ggaatttatc cgtaagacca ttcagcactt
     8401 ggcaagtaat gggtgtgatt tgattcgtct agatgccttt gcttatgcag tgaagaaatt
     8461 ggatactaat gatttctttg tggaaccaga tatttgggat ttattggaca aagttcgaga
     8521 tatcgctgct gagtatggga cagagctttt acctgagatt catgaacact attcgattca
     8581 gtttaaaata gcagaccatg attactatgt ttatgatttt gctcttccaa tggtgacact
     8641 ttatactctt tacagttcca gaacagagcg tttggctaag tggttaaaga tgagcccgat
     8701 gaagcaattt acgacgctag atacccatga tgggattgga gtagtagatg tcaaggatat
     8761 cctgaccgat gaggagattg actatgcttt aaatgaattc tataaggttg gagccaatgt
     8821 caaacgtaag tactctagtg ccgagtataa caacttagat atctaccaaa tcaattcaac
     8881 ctactattca gcgcttggag atgatgatgt caagtatttt ctcgctcgtc taattcaagc
     8941 ttttgcccca ggtattcctc aggtttacta tgtgggtcta ttagcaggca agaatgactt
     9001 gaaattatta gaagaaacta aagaaggtcg aaatattaat cgtcattact atagcaacga
     9061 ggaaatagca aaagaagtgc aacgacctgt tgtgaaggcc cttctcaatc tattttcttt
     9121 ccgtaaccgt tcagaagcct ttgatctaga agggactact gagatagaga caccaacagc
     9181 tcacagcatt gtaatcaaac gtcaaaataa agataagtcc gtaacagcag tagcagaaat
     9241 tgatttgcaa aatcagactt atcgggtaat tgagaatgga gttgaagtaa cattttgaag
     9301 ccttgatatg gtggataaaa tagggttttt attttggaaa acgtttcctt tgttttcaaa
     9361 ttgctaaaaa agtggtacaa tataggatag cttactatta tctgaatcag ctgatttgga
     9421 gagaaaggat tcattttgaa atcaataggc tttattgaaa agctgaaggg gttgtctagt
     9481 aaagagctga ttttattggg aattatcctg agtatctttt taccctttta tctttttgta
     9541 gttgtactct gtttatatat tatcagtttg atttttacag gagacatgaa aagtattctt
     9601 cagaaaatgg gggagcatcc gatgctgctt ctttttctta gctatagtac tgttatatcc
     9661 attcttgcac aaaattggat gggtcttgtg gcttcagtag gaatgtttct atttactatt
     9721 ttctttttgc actatcagtc gattttatcc cataaattct ttcgattgat tttgcagttc
     9781 gtcttgtttg gtagtgtctt gtcagctgct tttgccagtt tagaacattt ccaaattgtg
     9841 aagaaattta actatgcttt tctttcaccc aatatgcagg tgtggcatca gaaccgggca
     9901 gaagtgacct tctttaatcc taattattat ggaattattt gttgtttctg tattatgatt
     9961 gctttctatc tgtttacaac gaccaagttg aattggttga aagtattctg tgtgattgca
    10021 ggctttgtta atctctttgg tttgaacttt actcaaaatc gaactgcctt tcctgctatt
    10081 atcgctggag caattatcta tctctttacg actattaaaa actggaaggc tttttggctt
    10141 agtattgggg tcttcgcgat tggtttgagt ttcctctttt ctagtgattt gggagttcga
    10201 atgggtactt tagactcttc tatggaagaa cgcatttcta tctgggatgc tgggatggcc
    10261 ttgtttaagc aaaatccttt ttggggtgaa gggccattga cctatatgca ctcttatcct
    10321 cggatacatg ctccttatca tgaacatgcc cacagtcttt atattgatac gattctgagt
    10381 tacggaattg tgggtaccat tttattagtt ctgtcttctg ttgctcctgt tcgtttgatg
    10441 atggatatga gtcaggagtc ggggaaacgt ccgattatcg gcctttatct atctttcctt
    10501 acagtggttg ctgtgcacgg aatttttgac ttggctctct tctggattca gtcaggcttt
    10561 attttcttgc tagttatgtg cagtattcca ttggagcatc gaatgttggt atcggacatg
    10621 acggattaag ttttataagt ttgaaatctt ctaccttggg taggagattt tttatacgat
    10681 gggcatgtcg tgcatctgag gtgtaagtcc tctgtaggga tccactaccg gtgaatacaa
    10741 tagcgctccc caagcctgac tatcgtgagg tagcggatta aaatggtctg gggatagatc
    10801 gttttaagtc tgacgcagga aataagaatt gtcagagaaa gcaatagtga aatcgtaggc
    10861 tatgaataga aacgtgatag cgaggagcat atagtggaca aggtagcgag aaattttaaa
    10921 gtataaaaga tagtcttaat ctatatgtgt aaatcacgaa agtaattgaa ttcggaataa
    10981 ggttggtgtg aaaagacata gtaaactgaa tcttgaatac tagaatgata cttctacaat
    11041 attgttataa tttaatttga attccaaaat cacattgttc cgtccgtatt tcattttact
    11101 gtatgtcttc ctaagctcca aaatttctgt gtcaaatttc ctattttcac tgtagtcttt
    11161 gacacttcga acgacaattt gaatcatata ttcaaaaaaa atgaaaaatt tgtgccaaca
    11221 agcctaaata ttctgaaaat ttgtttgatt tttaatggat aatgtgatat aatggttgtc
    11281 aatctataat tcacataaac agaggagtag aaaatgaaaa aaaatcgtgt atttgctaca
    11341 gcaggtcttg ttttattagc agcaggtgta cttgcagcat gcagttcttc aaaatcatct
    11401 gattcatcag cccctaaagc ttatggctat gtttatacag cagacccaga aaccttggac
    11461 tacctgattt caagtaaaaa tagtacaaca gtagtgactt caaatgggat tgatggttta
    11521 ttcactaacg ataattacgg taatcttgct cctgcagttg cagaggattg ggaagtctct
    11581 aaggatggtt tgacctacac ttataagatt cgtaaagggg ttaaatggtt tacctctgat
    11641 ggagaagaat atgcagaggt gacggctaaa gatttcgtga acggtttaaa acacgcagca
    11701 gataaaaaat cagaagctat gtatttagct gaaaattcgg ttaaaggctt ggcagattat
    11761 ctatcaggaa cttcaacaga tttttcaaca gttggtgtca aggcggttga tgattatacg
    11821 ttacaataca ctttgaacca gcctgaaccg ttctggaact ctaagttgac ctattctatt
    11881 ttctggcctc tgaatgaaga attcgaaaca tcaaaaggaa gcgattttgc taaaccaaca
    11941 gatccgacat ccttgcttta taatggtcca ttcttgttga aagggttgac tgcaaaatct
    12001 tctgtagagt ttgtaaaaaa tgagcaatat tgggataaag aaaatgtcca cctagatact
    12061 atcaatctag cttactatga tggatcagat caggagtcgc tagagcgtaa cttcactagt
    12121 ggagcttata gttatgcccg tctttaccct accagctcca actattctaa ggttgcagaa
    12181 gaatacaagg acaatatcta ttacacacaa tcaggctctg ggattgctgg tctgggtgtg
    12241 aatattgatc gccaaagtta caactatact tctaaaacta cagattcaga gaaagtagct
    12301 actaagaagg cattgcttaa caaagatttc cgtcaagcct tgaattttgc tcttgatcgc
    12361 tcagcttact cagctcaaat caatggtaaa gatggagcag ctttagcagt tcgtaattta
    12421 tttgtaaaac cagactttgt ttcagctggt gagaagacct ttggtgattt agtcgctgct
    12481 caacttcctg cttatggtga tgagtggaaa ggtgtgaatt tagctgatgg gcaggatggt
    12541 ttattcaatg ctgacaaggc caaggcagag tttgcgaaag ctaagaaagc tttagaagca
    12601 gacggcgttc agtttcctat tcatctggac gttccagtag accaagcatc aaaaaactat
    12661 atatctcgta ttcagtcctt taaacaatct gtagaaacag ttcttggtgt tgaaaatgtc
    12721 gttgttgata ttcaacaaat gacaagtgat gaattcctta atattactta ctatgctgcc
    12781 aatgcttcat ctgaggattg ggatgtatcg ggaggagttt catgggggcc agactatcaa
    12841 gacccatcta cttacctgga tattttaaaa acaactagca gtgaaactac aaaaacatat
    12901 ttaggatttg ataatccaaa tagcccttca gtagttcaag ttggtttgaa agaatacgat
    12961 aaattagttg atgaagctgc caaagagaca agcgacttga atgtccgtta tgaaaaatat
    13021 gcagcggctc aagcatggtt gacagatagt tcactcttta ttcctgctat ggcttcttct
    13081 ggtgcagcac cagtgctttc acgaattgtt ccatttactg gagcttctgc gcaaacaggc
    13141 tctaaggggt cagatgttta cttcaaatat ttgaaattac aagataaagc ggtgactaag
    13201 gaagagtatg aaaaagctcg tgaaaaatgg ttgaaagaaa aagctgaatc aaatgagaaa
    13261 gctcaaaaag aattggcaag tcatgtgaag taaataattt ctaatagaac tttctctcca
    13321 tgaggagaag gttcttttgg gatttttaaa ggaaataata tgaaaaaata tatttttatg
    13381 cgtgttttgc ggtcattggt ttcgattttc ttagtaacga ctttgaccta cacgattatc
    13441 tataccttgg ttcctcgaaa attgattttc aagcaggatc ctaactataa taaaattgcg
    13501 acaacggctg ataaacgtga taactatgaa aatactgtgt ttgagcgtat gggctacatt
    13561 gagtattacg atactaaaga gttgcaagaa aaggcaagta gcatggattc ttctgtaaca
    13621 gtagaagcaa atgcgaccaa taaagctatt tatgaaaagt acatcaatca attaggtcat
    13681 ggttggactt tgggagaatt tactgaaagt ggtcaattct atgctactcg tgaaattcca
    13741 atttttgaac gtgtttttca cttctatgct aacttgattg acattgacca tacaaataaa
    13801 atccaagacc ctgaaaatcc agacttgaaa cgctaccttc gttttgaaaa tgatccagct
    13861 atcggatggt cattggtcgg ttcaggaact aaacataaat atctcttgta ctttaacagt
    13921 cagttcccat ttgttcatca aaactttgtg aacttgaatt taggtgactc ttacccaacc
    13981 tatgctaata caccagttct tcaggttatt actcaaggtc aaggacaaac caaaactgcc
    14041 caagttcagt tcccaacagg taagaaaacg tcttctgtaa atatttactc aagaacctac
    14101 aagtcaccta gtcaggctga ctctcgtgaa gtagctagct atgggaaaga tgatccttat
    14161 acagcgactg aaagtaatta ccaatatcca tctatgattg tcagctctgc tattactggt
    14221 ttgattggtt tggttcttgc ctatgctctt gccgtgccac ttggttcagc catggctcgt
    14281 ttcaagaaca cttggattga tagcctctca acaggggctt tgaccttctt gcttgctctt
    14341 ccaacgattg ccttggttta catcgttcga ttgattggat catctattgc ccttccagat
    14401 tcattcccta tcttgggagc tggagattgg cgttcttacg ttttaccagc agtcatcctt
    14461 ggtttgttgg gtgctcctgg tacagccatt tggattcgtc gttacatgat tgacttgcaa
    14521 tctcaagact ttgttcgttt cgctcgtgca aaaggtttgt ctgaaaaaga aatttcaaac
    14581 aaacacatct ttaaaaatgc catggttccg ctggtttcag gaattcctgg tgccatcatt
    14641 ggggttatcg gtggtgcaac ccttactgaa acagtcttcg ccttcccagg tatgggtaaa
    14701 atgttgattg actctgtaaa agcatctaat aactctatgg tcgttggtct tgtcttcatc
    14761 tttacatgta tttctatctt ctcacgtctt ttgggagata tttggatgac tattattgac
    14821 ccacgtatta aattgactga gaaaggaggc aaataatgtc tacaatcgat aaagaaaaat
    14881 ttcagtttgt aaaacgtgac gattttgcct ctgaaactat tgatgcgcca gcatattctt
    14941 actggaaatc agtgtttaaa caatttatga agaaaaaatc aactgtagtc atgttgggaa
    15001 tcttggtagc catcattttg ataagtttca tctacccaat gttttctaag tttgatttca
    15061 atgatgtcag caaggtaaac gactttagta ttcgttatat caagccaaat gcggagcatt
    15121 ggttcggtac tgacagtaac ggtaaatcgc tctttgacgg tgtctggttc ggagctcgta
    15181 actccatcct catttctgtg attgcgacag tgattaactt ggttatcggt gtttttgtcg
    15241 gtggtatttg gggtatttca aaatcagttg accgtgtcat gatggaagtt tacaacgtca
    15301 tctcaaacat cccacctctt ttgattgtta ttgtcttgac ttactcaatc ggagctggat
    15361 tctggaatct gatttttgcc atgagcgtaa caacatggat tggtatcgcc ttcatgatcc
    15421 gtgtgcaaat cttgcgctat cgtgacttgg aatacaactt ggcgtcacgt actttgggaa
    15481 caccaacctt gaagattgtt gccaaaaata tcatgcctca attggtatct gttattgtga
    15541 caaccatgac tcaaatgctt ccaagcttta tctcatacga agccttcttg tctttcttcg
    15601 gtcttggatt accgattaca gtgccaagtt tgggtcgttt gatttcggat tattcacaaa
    15661 acgtaacaac caatgcttac ttgttctgga ttccattgac aacccttgtc ttggtatcct
    15721 tgtccctttt cgtagttggt caaaacttag cggatgctag tgatccacgt acacatagat
    15781 aggagtagaa atgacaaaag aaaaaaatgt aattttgact gctcgcgata ttgtcgtgga
    15841 atttgacgtt cgtgacaaag tattgacagc cattcgcggc gtttcccttg aactagttga
    15901 aggagaagta ttagccttgg taggtgagtc aggatcaggt aaatctgttt tgacaaagac
    15961 cttcacaggt atgctcgaag aaaatggtcg cattgtccaa ggtagtattg actaccgtgg
    16021 tcaggatttg acagctttat cttctcacaa ggattgggaa caaattcgtg gtgctaagat
    16081 tgcgactatc ttccaggacc caatgactag tttggacccc attaaaacaa ttggtagtca
    16141 gattacagaa gttattgtaa aacaccaagg aaaaacagct aaagaagcga aagaattggc
    16201 cattgactac atgaataagg ttggcattcc agacgcagat agacgtttta atgaataccc
    16261 attccaatat tctggaggaa tgcgtcaacg tatcgttatt gctattgccc ttgcctgccg
    16321 acctgatgtc ttgatctgtg atgagccaac aactgccttg gatgtaacta ttcaagctca
    16381 gattattgat ttgctaaaat ctttacaaaa cgagtatcat ttcacaacaa tctttattac
    16441 ccacgacctt ggtgtggtgg caagtattgc ggataaggta gcggttatgt atgcaggaga
    16501 aatcgttgag tatggaacgg ttgaggaagt cttctatgac cctcgccatc catatacatg
    16561 gagtctcttg tctagcttgc ctcagcttgc tgatgataaa ggggatcttt actcaatccc
    16621 aggaacacct ccgtcacttt atactgacct gaaaggggat gcttttgcct tgcgttctga
    16681 ctacgcaatg cagattgact tcgaacaaaa agctcctcaa ttctcagtat cagagacaca
    16741 ttgggctaaa acttggcttc ttcatgagga tgctccaaaa gtagaaaaac cagctgtgat
    16801 tgcaaatctc catgataaga tccgtgaaaa aatgggattt gcccatctgg ctgactagga
    16861 ggaaggaaat gtctgaaaaa ttagtagaaa tcaaagattt agaaatttcc ttcggtgaag
    16921 gaagtaagaa gtttgtcgcg gttaaaaatg ctaacttctt tatcaacaag ggagaaactt
    16981 tctcgcttgt aggtgagtcc ggtagtggga aaacaactat tggtcgtgct atcatcggtc
    17041 taaatgatac aagtaatgga gatatcattt ttgatggtca aaagattaat ggtaagaaat
    17101 cgcgtgaaca agctgcggaa ttgattcgtc gaatccagat gattttccaa gaccctgccg
    17161 caagtttgaa tgaacgtgcg actgttgatt atattatttc tgaaggtctt tacaatcacc
    17221 gtttatttaa ggatgaagaa gaacgtaaag agaaagttca aaatattatc cgtgaagtag
    17281 gtcttcttgc tgagcacttg actcgttacc ctcatgaatt ctcaggcggt caacgtcaac
    17341 gtatcggtat tgcccgtgcc ttggtcatgc aaccagactt tgttattgca gatgagccaa
    17401 tttcagcctt ggacgtttct gtacgtgccc aagtcttgaa cttgctcaaa aaattccaaa
    17461 aagagctcgg cctgacctat ctcttcatcg cccatgactt gtcggttgtt cgctttattt
    17521 cagatcgtat cgcagttatt tacaagggtg ttattgtaga ggttgcagaa acagaagaat
    17581 tgtttaacaa tccaattcac ccatatactc aagccttgct ttcagcggta ccaatcccag
    17641 atccaatctt ggaacgtaag aaggtcttga aggtttacga tccaagtcaa cacgactatg
    17701 agactgataa gccatctatg gtagaaatcc gtccaggtca ctatgtttgg gcgaaccaag
    17761 ccgaattggc acgttatcaa aaaggactaa actagtaatg gttttataat ttccatgtca
    17821 atttttatgg aaattataaa actttttttg ttggactgat ttgaaaaact ttgaaagctt
    17881 cctgaaagaa tttttgaaaa attttaaaaa ttatgaaata ttattgacag gtgacgaaaa
    17941 aggtggtagg ataggaagca tcaaaaaaga aagcagaaaa agaaatgaat aagagacaag
    18001 ccgtaactat gaatcaaaac ttttacttta gctactttag atagtgtttg tagacatgtc
    18061 accatggatg caaacagttc aagcaatttg tttgtatcta tgtggctaag atttttgatt
    18121 gtggtccata tagatgaata tctaaatgga ctagctaagt tgtaacttgt taggttattt
    18181 caagtatccg tttagatagt atctaggcgg ttttttgttt tatcttttct gagaaggagt
    18241 ttcattatga aagttgttcg aaaatcacta gccccctctt ggtagtgggg atcctcttga
    18301 cttctctgat cagtttgcat cagttgaagg cagataagaa aagagatgtc tttcgtatcg
    18361 gtatttcgca gtttattacc caccagtcct tagacgctac tagagaagga tttgtggatg
    18421 agctggccaa acaaggctat gttgaggggg aaaatattga gattgatttg caaaatgcac
    18481 agggagaaca aagaaatcta aaaacgattt cccagcaact agcagaatcc agcgatgtcg
    18541 ttctagccat cgcaaggcct tctgctcaga gcttggccaa tacgacgcaa acgacaccag
    18601 ttatcttttc agctgtaaca gacccagtca gtgccaagtt ggttgagtca agagaacatc
    18661 ctgggggcaa tgtaactggg acaagcgatc agtcatcaga tgccatttca acccaaatca
    18721 atttgataaa gaaagtgttg ctaaaggcta aaacgattgg aatcctctat actcagagcg
    18781 agcccaattc ggttgtttaa aaggatgaag ctaagcgact tctgaaagaa aaaggcttta
    18841 ccgttgttga aaaaacaatc ttggacagta ataacatcaa ggcggcagca gagagtttga
    18901 tggcagaggt ggatatggtt tttgtcccaa ctgataatat catttcgtca accatggaaa
    18961 cagttaagca ggtttctatt aaacacaagg ttccagtatt cggtggttca acagaaatga
    19021 ttgctgttgg tgacttgtat aactacggaa ccaattatga agaattggga agacagacag
    19081 ctcgcatgct gattcgtgtt ttaaaaggtg agaaaccaga aaatatagca gttgagttgc
    19141 ctgaaaaact ggaattgcat actaatcaag aaatggcaga tgcattggga attgatatta
    19201 gtaagttaga aggcaaggaa taaggaggat taagatgaat tttgtgttat ctagtttatc
    19261 agaaggtttg ttgtggtcga ttgtggcgat tggggtctac ttgactttcc gtattttgga
    19321 tattgcggat atgactgctg agggagcctt tcctctgggg gcagcagtcg ttgtatcaca
    19381 gatacaggca ggggcaaatc cttggcttgc gattttactt gctttgctgg caggtatggt
    19441 agcaggtctt gtatcaggaa tgctccacac caagatgaaa atcccagctc tcttgacagg
    19501 gattgtgacc ttgacagggc tctattcaat caatattaaa atcatgggca gtgtactcaa
    19561 tctttccttg ggagattctg caaccgtctt taaacagttg gcgagcttgg gtctgacaaa
    19621 tgaaggagct gttttctcac ttagtttagt ctgtctctta cttgtttggt cttgaccctt
    19681 ttgatgaaaa cagagattgg tttggtcttg cgttcgactg gggataatat cccgatgagt
    19741 gaggccaatg gagtcaatgt agacaccatg aagattgttg gttacatgat ttcaaacggt
    19801 ttgattgccc tatgtggttc cttgtttgcc caaaatgatg gattttcaga tgtgacttct
    19861 gggacaggaa ccattgttgt tggtttgagt tcggtgatta ttgcggaagt cttgatacac
    19921 gacttgacca ttggaggccg cttattatcc atcggaatcg gtgctattgt ttaccgtttg
    19981 attattttaa atatctatga aattccaaat ctagatcaaa acttggtacg tctctttaat
    20041 gcaatcttgc tcgctttggt tttatttgca ccagaattgc aaaagagatt aaagattcgt
    20101 ggtctgaaat tgagaaatga ataggaggag aaagttatgg caagtttgtt aacacttgaa
    20161 aatattcaca agacatttga agcagggacg gtcaatgaga accatgtcct caaaggatta
    20221 gatttagagg ttgaagaggg agattttatc tctgtgattg gtggaaatgg agcaggaaaa
    20281 tccactttga tgaatatctt ggctggcaat ctatcgatgg acgaagggga ccttctactg
    20341 gcagggaaat ccattaaaaa tctgagtgtc agaaagagag ccaaggatat tgcccgtgtt
    20401 tttcaagctc ctaagatggg aacagcttct cgtttgacga ttgaggagaa tatggctatt
    20461 gccttgagac gtgggcaaaa gagagggctt ggttggggcg tgaaggagaa ggatagaatc
    20521 cagttccaag aggccttgaa ggagttgaat attggtcttg aaaaccgctt aaaagtagat
    20581 actcaatatc tctcaggagg acaaagacag gctttgaccc tagtcatggc agctctggtg
    20641 aaacccaaac ttttgctttt ggatgaacat actgcggcac ttgacccgaa aaccagtcaa
    20701 atggtgatgg acttgacgca aaagattgtg gagcaccatc agttgacgac tttgatgatt
    20761 acccatgata tgaatcatgc gattgagtac ggcaatcgtc tcattatgct ctatcaaggc
    20821 aagatagtgg tggatgtcaa gggagaagag aaaaagcatc tgacagttga agaccttatg
    20881 catctcttcc agaaaaatag tggccaaagt ctggtcagtg atgaattagt tttgagataa
    20941 agaaaaaggc tgagattggt gtctcagtct tttatttctt gcgttttgca aaatctacaa
    21001 atctaaattt ttctaactta tggcgacttt cggtaaactg aaattggcgt ccgtcttgga
    21061 gatagacttt tgatttaatc gaaacgacat aagggtcttt gccaatgtcc atgagaatct
    21121 tgtctcggtc gcttgagtgg tcaatggtga tttccttctg agcataatca ataaggagtt
    21181 tgaggccatt ttctatataa gaatagatag actgctcagc aatttggcga gtgagatttg
    21241 ggatgagttc catatccaga tagtctgtat ccagaacgga taccagatca tccaccacac
    21301 gctggcggac caccttccaa accatccgaa actctgggaa accggttatc agtgaggatt
    21361 ttttatcaat aataatcttg tccagactga ccacgttggt tttagagcgc agtccaagtt
    21421 ctttaactag ttcttggtag ctggttaggt tggatacagg gaaattgacg gtttcttctt
    21481 tgacgacttg agaaccttgc cctcttatct ttttgatcaa tccttcctct tggaggagag
    21541 acagggcctt tcggacggta tcacgactca cttgatattg ctccataagg tcgtgctcgc
    21601 taggaaggaa atctccgaca gcgtaagtct cgttttgaat ggtttcttgg atttgcttaa
    21661 ataattgttg gtatttcttc attttgcctg cttaaatagg tttttagtct agtttaatga
    21721 acacctgtat ctattttacc atacaagtgc tagaaaattt acaaaaaaac acccttttta
    21781 taccaaacaa gttgcagaca agtttggtat cgtttacaat atacttatca aatcaaactt
    21841 gctttgacaa gtataaggag aatcaaatgg gaaaatttga acaagaagcc aaagatctgc
    21901 ttcaggcaat tggaggcaaa gaaaatgtga ctgccgtcac ccactgtgcg acacggatgc
    21961 gctttgtttt aggagatgat aagaaggcta atgttaaagc tatcgagtca attccagctg
    22021 ttaaaggaac ttttacaaat gcaggtcaat ttcaggtaat cattggaaat gacgtgccca
    22081 tcttttataa tgattttaca gccgtttcag gtattgaggg tgtttccaaa gaagcagcca
    22141 agtctgcagc taagagtaat caaaacgtgg tccaacgtgt tatgaccact ctggcggaga
    22201 tttttactcc gattattcca gccttgatag tcggaggatt gatcctcggt ttccgtaatg
    22261 tcttggaagg tgtccattgg tcgatgttgg atggcaagac catcacagaa tcctctcagt
    22321 tttgggcagg tgtcaatcac ttcctctggt tgcctggtga agctatcttc cagttcttac
    22381 cagtagggat tacttggtct gtttctcgta agatgggaac cagccaaatt ttgggaattg
    22441 ttctcggaat ctgtttggta tcgcctcagt tgctcaatgc ctatgcggtt gcttcaacgc
    22501 cagcagctga tatcgcggca aactgggttt ggaattttgg ctattttact gttaatcgta
    22561 tcggttacca agcccaagtt atcccagcct tgcttgcagg tttgagtctg tcttatcttg
    22621 aaatcttctg gcgcaagcat atcccagaag tcatttctat gatttttgta cctttcttgt
    22681 cattgattcc agccttgatt ttggctcata ctgttttggg accaatcggt tggacaattg
    22741 gacaaggact ttcatcagtt gtcttggcag gtttaactgg tccagttaaa tggctcttcg
    22801 gtgcaatttt tggtgccctc tacgctccat ttgtcatcac aggtctgcac catatgacca
    22861 atgccattga tacacaattg attgcggatg ctggtggcac tgccctatgg ccaatgattg
    22921 ctctttctaa tattgctcaa ggctcagccg tgtttgccta ttatttcatg catcgccatg
    22981 atgagcgtga ggctcaggtt tcacttcctg caaccatttc agcctatctc ggtgttacag
    23041 aaccagctct ttttggggtt aacgtaaaat atatttatcc atttgttgct gggatgactg
    23101 gttcagccct tgcaggcatg ttatccgtta cttttaatgt aactgcggct tctattggta
    23161 tcggtggttt gccaggtatt ctctctattc aacctcaata catgctgcca tttgcaggaa
    23221 ctatgctagt tgcgattgtt gttccaatgc tcttgacttt cttcttccgc aaggctggtc
    23281 tctttacaaa aacagagggc gatacgaact tgcaggcaga attcgttgct caagaagaag
    23341 cagaatttgt gaaccatgaa ccagtagaac ttacttcggt agaaattatc agcccactaa
    23401 ctggccaagt gaaagaattg agtcaagcga cggatcctat ttttgcatca ggtgtcatgg
    23461 ggcaaggtct agtcattgaa ccaagccaag gtgagttgac ctctccagtt aatgggacag
    23521 tgacggttct tttccctacc aagcatgcca tcggcattgt ctctgacgag ggagttgaat
    23581 tgctcatcca catcggtatg gatacagtag gtcttgatgg caaaggtttt gaaagtcttg
    23641 tagtccaagg agatcacgtt acagttggtc agcaactgat tcgttttgat atggatgtca
    23701 ttaaggctgc aggtctggtg acagaaactc ctgttatcat caccaaccaa gatgcttata
    23761 cagcgactat tcccggaact tatccgacaa cgatccaagc tggagcatct ctcatggtcg
    23821 ctacacgaat ctaatactct tcgaaaatct cttcaaacca cgtcagctct atctgcaacc
    23881 tcaaaatagt gttttgagca acctgtggct agcttcctag tttgttcttt gattttcatt
    23941 gagtataatt gaaatagcac aaatagggac ggaagactgc ttcctccctt ttatcagaaa
    24001 aggagaaaca gatgacactt gataaaggaa aagtagtcta tcaaatctat ccaaaatctt
    24061 acaaagacac cactgaaaac ggtattgggg atttccgtgg gattatcgaa aaaattccct
    24121 atttagccaa actaggtgtg gatatggtct ggctcaatcc attctatcca agccctcaac
    24181 gggataatgg ttacgatatt tcagattata tggcagtgga tcctcttttt ggtgatatgg
    24241 ctgattttga ggaaatggtg tgtgtcggta aagagcacaa gattgacttt atgctggaca
    24301 tggtacttaa tcattgttcg acagagcatg aatggtttca gaaagcccta gctggtgata
    24361 agtattatca agactttttc ttcatccaag accaaccaac agattggcag tctaagtttg
    24421 gtggttctgc atgggcgcct ttcggggata ctgggaaata ctatcttcac ctatttgatg
    24481 agacccaggc tgaccttaac tggcgcaatt ccaatgtccg taaggagctt ttcaaggttg
    24541 ttaatttctg gcgcgacaag ggtgtcaaag gtttccgatt tgatgtgatc aatttgatcg
    24601 gtaaggacga ggtttcagtg gactgtcctg aaaatgaagg gaagccagct tatacagaca
    24661 aacccatcgt tcataactat ttgcgtatga tgaaccaagc cacttttgga tctgacgata
    24721 gctttatgac agttggggaa atgtcttcta ccaccatgga aaactgtgtc ctctattcgt
    24781 cgcctgatcg tcaggaatta tccatgacct ttaattttca tcacctcaag gtggactata
    24841 aggatggaca aaagtggacc ttggctccct ttgattttga agagttgaag agtctttacc
    24901 atagttgggg taaggaaatg agtgataaag acggttggag tgccctcttt tggaacaatc
    24961 acgatcaacc acgtgccttg aaccgttttg tcgatattca aaacttccgc aaggaaggag
    25021 ctaccatgct agcagccagc attcacctgt cacgtgggac accttatatc tacatgggtg
    25081 aggaaatcgg gatgattgac ccagactatg attctatggc tgattatgtg gatgtcgaat
    25141 cgcttaatgc ctatcagatg ctcttagaag aaggaaagag tcagcaagaa gccttccaga
    25201 ttattcaagc taagtcgcgt gataattcac gtattcccat gcagtgggat acttctgaaa
    25261 atgcaggatt ttcaacaggc actccatggt tgaaagttgg taaatcctat aaagatatca
    25321 atgtagaaaa tgaaatcaaa ggtctgattt tcaccttcta tcaagacttg attcgactgc
    25381 gtaaggaaat gccaatcatt tcagaaggaa attacaaacc agcctttgaa gatagcaaac
    25441 aagtctacgc ttttgaacgc cagtttgagg atcaaaagtt actagtgctc aataactttt
    25501 atgccaaaga agtggaaatc gacttgccag cagtctacca aaatggacag attttgattt
    25561 caaactatga agatgcagaa gtgtctgaga aaattctact caaaccctat caaacactgg
    25621 ctatttatgt aaattaatac tcttcgaaaa tctcttcaaa ccgtgtcagt tttatctgta
    25681 acctcaaagc ggtgctttga gcaacctgtg gctagcttcc tagtttgctc tttgattttc
    25741 attgagtata aacttagcaa ggagacctct ttttcagaaa agcagggttc tttttgctgt
    25801 ctattccatc cttgaaagtg tagaacaaac tggtcagggt ggctagtttg tggtataatg
    25861 aaagggactc aaaaagaaac aggagaaaaa tgatggattt acttttagca attgtattga
    25921 ttgtgctagc ttttctagga ggagctcttg gaggaatgta cttggttcgt aagcaaatcg
    25981 aaaaagaatt tgctgacaac ccacgtttga atgctgaagc agttcgtact cttttgagtg
    26041 caaatggtca aaaaccaagc gaagctaagg tacaacaagt ttaccaccaa atcatccgcc
    26101 aacaaaaggc agcccttgct aacaataaaa agaaaaaata aataaggaaa agtctgggat
    26161 gaaagttcca gacttctcac tatgttggtt atggtttagg gatgagactt tttccttgca
    26221 ttctattgat atttgattat gattaagaga gaggtagttg acattctatc aagctgtcgg
    26281 tcagttcgtt cagtacaagg aatcataatg aacgatcaat cagaaaaaag actagaaaga
    26341 agactgtatg gataatcgac caattggttt tttggattcg ggtgtcgggg gcttgaccgt
    26401 tgtgcgcgag ctcatgcgcc agcttcccca tgaagaaatc gtctatattg gagattcggc
    26461 gcgggcgccc tatggccccc gtcctgctga gcaaattcgt gaatatactt ggcagctggt
    26521 caactttctc ttgaccaagg atgtcaaaat gattgtcatt gcttgtaaca ctgcgactgc
    26581 ggtcgtctgg gaagaaatca aggctcaact agatattcct gtcttgggtg taattttgcc
    26641 aggagcttcg gcagccatca agtccagtca aggtgggaaa atcggagtga ttggaacgcc
    26701 catgacggta caatcagaca tataccgtca gaaaatccat gatctggatc ccgacttaca
    26761 ggtggagagc ttggcctgtc ccaagtttgc tcccttggtt gagtcaggtg ccctgtcaac
    26821 cagtgttacc aagaaggtgg tctatgaaac cctgcgtccc ttggttggaa aggtggatag
    26881 cctgattttg ggctgtactc attatccact ccttcgccct attatccaaa atgtgatggg
    26941 gccaaaggtt cagctcatcg atagtggggc agagtgcgta cgggatatct cagtcttact
    27001 caattatttt gaaatcaatc gtggtcgcga tgctggacca ctccatcacc gtttttacac
    27061 aacagccagt agccaaagtt ttgcacaaat tggtgaagaa tggctggaaa aagagattca
    27121 tgtggagcat gtagaattat gacaaataaa atttatgaat ataaggatga ccaggactgg
    27181 tatgttgggt cttatagtat ttttggtggc gttaacagtt tgagcgacta taagacagat
    27241 tttcctctgt ttgaattctc caaaatattt ggagatgaag agtatggttt cccgctttca
    27301 gttactgttt tacgctatgg ttctacctac cgtttgttct cctttgtggt agacatgctt
    27361 aatcaagaaa tgggacgaaa cttggaagtt attcaacgtc atggggccct gctcttggtt
    27421 gaaaatgggc aactcttgta tgtagaattg cctaaagaag gggtcaatgt tcatgatttc
    27481 tttgagacaa gcaaggtcag agaaaccttg ttgattgcga ctcgtaacga aggtaaaacc
    27541 aaggaattcc gagctatctt tgataagtta ggctacgatg tggaaaatct taatgactac
    27601 cctgacctgc ctgaagtagc agaaacaggt atgacctttg aagaaaatgc ccgccttaag
    27661 gcagaaacca tttctcaatt aacgggcaag atggttttgg cagatgattc tggtctcaaa
    27721 gtcgatgtcc ttggtggctt accaggcgtc tggtcagctc gtttcgcagg tgtgggagca
    27781 actgaccgtg aaaataatgc caaactcttg cacgaattgg ccatggtctt tgaactcaag
    27841 gaccgctcgg ctcagttcca cacaacccta gtcgtagcca gcccaaataa ggaaagttta
    27901 gttgttgaag cagactggtc aggttatatt aactttgaac ctaagggtga aaatggcttt
    27961 ggctatgatc ccctcttcct tgtaggagag acaggtgagt catcagctga attaaccctg
    28021 gaagaaaaaa atagtcaatc tcaccgtgcc ttagccgtta agaaactttt ggaggtattt
    28081 ccatcatggc aaagcaaacc atcattgtaa tgagcgattc ccatggcgat agcttgattg
    28141 tggaagaagt ccgtgatcgc tatgtgggca aagtcgatgc cgtttttcat aacggcgatt
    28201 ctgaactacg tccggattct ccactttggg agggcatccg cgttgttaaa gggaacatgg
    28261 acttctacgc cggctaccca gaacgtctgg tgactgagct tggttcgacc aagattatcc
    28321 aaactcatgg tcacttgttt gacatcaatt tcaactttca aaagttggac tactgggctc
    28381 aggaggaaga ggccgctatc tgcctctatg gtcacttgca tgtgccaagt gcttggatgg
    28441 aaggcaagat cctctttcta aatccaggtt ctatcagcca accacgaggt accatcagag
    28501 aatgtctcta tgctcgtgtg gagattgatg atagttactt caaagtggac tttttgacac
    28561 gagatcacga ggtgtatcca ggtttgtcca aggagtttag ccgatgattg ccaaggagtt
    28621 tgagactttc ttgttggggc aggaggaaac ttttttgacc cctgctaaaa atctagctgt
    28681 gttgattgat acccacaatg cggatcatgc gaccctcttg ctcagtcaga tgacctatac
    28741 ccgtgttccc gttgtgacag atgaaaaaca gtttgttggg acgattggac tcagagatat
    28801 tatggcttat cagatggagc atgacttgag ccaagaaatc atggcggata cggatatcgt
    28861 tcatatgaca aaaacggacg tagcggttgt ttcgcctgat ttcaccatta cggaggtctt
    28921 gcacaagcta gtagatgagt ccttcttacc ggttgtggat gcagagggta ttttccaagg
    28981 gattattacg cgcaagtcca tcctcaaggc cgttaatgcc ctcttgcatg actttagtaa
    29041 ggaatatgag attcgatgcc aatgagagac aggatttcag cctttttaga ggaaaagcag
    29101 ggcttgtctg tcaattccaa gcagtcctat aagtatgatt tggagcaatt tttagacatg
    29161 gtaggtgagc ggatttctga gaccagtctc aagatttacc aagcccagct agccaatcta
    29221 aaaatcagcg cccagaagcg aaagatttcg gcctgtaacc aatttctata ctttctctat
    29281 caaaaaggag aggtggacag cttttaccgc ttggaattag ccaaacaagc tgaaaagaag
    29341 acggaaaagc cagagattct atacctagac tctttttggc aggaaagcga ccatccagag
    29401 ggccgcttgc tagcgctctt aatcctagaa atggggctct tgcccagtga gattttagcc
    29461 atcaaggttg cggacatcaa tctggatttt caggtgttgc gaatcagcaa ggcttcccaa
    29521 cagaggattg tcaccattcc cacggccttg ctttcagaat tggaaccctt gatggggcag
    29581 acctatcttt ttgaaagagg agagaaaccc tattctcgtc agtgggcctt tcgtcagtta
    29641 gaatcttttg tcaaggagaa aggttttcca tccttatcag ctcaagtctt acgtgaacag
    29701 tttattctaa gacaaataga aaacaaggtc gatttgtacg aaattgcaaa aaaattagga
    29761 ttaaaaacag tcctgacctt agaaaaatat agataatgga tattaaatta aaagattttg
    29821 aaggacccct ggacttgctc ttgcatctgg tttctaagta ccagatggat atctacgatg
    29881 tgcccattac ggaagtcatc gaacagtatc tagcctatgt ctcaaccctg caggccatgc
    29941 gtctggaagt gacgggtgag tacatggtca tggctagtca gctcatgctg attaagagtc
    30001 gtaaactcct tccgaaggta gcagaagtga cagacttggg ggatgacctg gagcaggacc
    30061 tcctctctca aatcgaagaa tatcgcaagt tcaagctctt gggtgagcac ttggaagcca
    30121 agcaccaaga acgggcccag tattattcca aagcgccgac agagttgatt tacgaagatg
    30181 cggagcttgt gcatgacaag acgaccattg acctcttttt ggctttttca aatatcctag
    30241 ccaagaaaaa agaggagttt gcacaaaatc acacgacgat cttgcgggat gagtataaga
    30301 ttgaggacat gatgattatc gtgaaagagt ccttgattgg acgagatcaa ttgcgcttgc
    30361 aggatttgtt caaggaagcc cagaatgtcc aagaggtcat caccctcttt ttggcaaccc
    30421 tagagttaat caaaacccag gagctgatcc tcgtgcaaga ggagagtttt ggagatatct
    30481 atctcatgga aaagaaggaa gaaagtcaag tgcctcaaag ctagacttga tagagaggaa
    30541 agatgagtac tttagcaaaa atagaagcgc tcttgtttgt agcgggtgaa gatgggattc
    30601 gggtccgcca gttagctgaa ctcctctctc tgccaccgac aggcatccag caaagtttag
    30661 gaaaattagc ccagaagtat gaaaaggacc cagattccag tttggctttg attgagacaa
    30721 gtggtgctta tagattggtg accaagcctc aatttgcaga gattttgaag gaatactcta
    30781 aggcgcctat caaccagagc ttgtctcggg ctgcccttga gaccttgtcc attattgcct
    30841 acaaacagcc gattacgcgg atagaaattg atgccatccg tggagttaac tcgagtggag
    30901 ccttggcaaa gttgcaggct tttgacctga taaaggaaga cgggaaaaag gaagtattgg
    30961 ggcgccccaa cctctatgtg actacagatt atttcctaga ttacatgggg ataaaccatt
    31021 tagaagaatt accagtgatt gatgagcttg agattcaagc ccaagaaagc caattatttg
    31081 gtgaaaggat agaagaagat gagaatcaat aagtatattg cccacgcagg tgtggccagt
    31141 aggagaaaag cagaagagct gattaagcaa ggcttggtga cggttaacgg tcaagtggtg
    31201 cgtgaactag caaccactat caagtcaggc gacaaggtcg aagttgaagg tcaacctatc
    31261 tacaacgaag aaaaggtcta ctatctgctt aacaaaccac gcggtgtcat ttccagtgtg
    31321 acagatgata agggtcgcaa gacggttgtc gacctcttgc ccaatgtcaa agagcgtatt
    31381 taccctgtgg gtcgtttgga ctgggataca tcaggagtct tgattttgac caatgatggg
    31441 gactttacag acgagatgat tcaccctcgt aatgagattg acaaggttta tgtcgcgcgt
    31501 gttaaaggtg tggccaataa ggacaatctt cgccccttga cccgtggtct tgagattgat
    31561 ggtaagaaaa ccaagccagc tgtttatgaa attctcaaag tggacccagt caaaaatcgc
    31621 tctgtggtgc agttgaccat ccatgaaggg cgtaaccatc aggttaaaaa gatgtttgaa
    31681 gctgttggtc tccaagtaga taagttgtct cggactcgtt tcggacacct agacttgaca
    31741 ggactccgtc caggagaatc ccgtcgtctt aataaaaaag aaatcagcca actacacacc
    31801 atggctgtaa ctaagaaata atgaaacgaa ttttaatagc gcttgtgcgc ttttaccaac
    31861 gttttatctc accagtcttt ccaccctctt gtcgctttga gctgacttgt tccaactaca
    31921 tgattcaggc tattgaaaaa catggtttta agggggtatt gatgggcttg gctcggattt
    31981 tacgttgtca tccctggtcg aaaacaggta aggaccccat tccagaccac ttttccctta
    32041 aacgaaatca agaaggggaa tgaggtgggg taaatagatt tcaaaatgat aaaaacgcat
    32101 cctatcaggt ttgagtaaac ttgataggat gcgttttaga atgtcaaaat tttatactct
    32161 tcgaaaatct cttcaaaccg cgtcagcttt catctgcaac ctcaaaacag tgttttgagc
    32221 aacctgcggc tagtttccta gtttgctctt tgattttcat tgagtattaa attgagtttg
    32281 aagtggctta tttcaaagct ttttgtatgt cttcaatcat gagttttgtt gattcaagtc
    32341 cgcctccgct tagataccag aggtctggtg ttagttggat aatcttacca tttttagcag
    32401 caggtgtttc agcgataagg gcattttcta ggacaccgtc gttgctagag ttgtccccac
    32461 cgatggcaag ggtacggttg atgacaaaga ggatgtcagg gttgatttct ttgacacttt
    32521 caaagctgac ttcttgtccg tggcgtgagt cttcaaattt tgtatcagtt ggtttgaatt
    32581 tcaaggtttg gtacaagaaa gagaaacgag atttggcacc aaaggctgcc atttttcctt
    32641 cattaaggag gatcgcaagg gcttttttgt cagagctttc atttttagta gcgacttctt
    32701 ggatgctctt gtctagcttg gccaattctt ccttggcttt ttgtgtacta gtttcgccga
    32761 aggcacttgc taaggattcg atattagcct tggtagaagt ccagtagtca tccttgcttg
    32821 cttggaagag aacggttggg gcgatttctt tgaatttgtc tacgaatttt tgtgtacgtg
    32881 gtgaagcgat aatcaaatca ggctcaaggg cggcgatagc ttctaaatca ggttctttca
    32941 tagaaccaac atttttgaca gttcccacta ggtcttttag ataagtcgga acagtttttg
    33001 taggcattcc gacgatattt ttttcaaatc ctaaagcgcg aatagtatcc gcagcgccga
    33061 ggtcaaaggt cacaatcttt tcaggaactt tggaaagttt gacctcgtcc agtgaacttt
    33121 taatggttat ctctgttgga gcagagctac tggtctctgt ctgactagtg cttgagtttg
    33181 tactacatgc accaagtagg agcaagaagc tggccactag ggcagtgaaa taaagtttaa
    33241 gggatgtttt cataatttct cctttttaaa atgtgataac gatttaggga gtctcttaat
    33301 cttattgact aagagactga aggttctcta acttgagctt ttatgttact agctatagat
    33361 acagatcttt ttgttattga tatcagctag cgtgatggga atctcataaa gttgactgag
    33421 caggtcagcc tgcatgattt gatcggttct tcccttgcta aagacctggc cgtccttgaa
    33481 ggcgacaatt tcatctgcat actgactggc catgttgata tcgtggagga cgatgataat
    33541 ggtcttgccg agttcctcca ccagtcgtcg aagaatctgc atcatgctga cgctttgctt
    33601 gatatcgaga ttgttgagtg gttcgtccag caagataaag tccgtatcct gggccagtac
    33661 catagcgata aagacgcgct ggagttgccc ccctgacagg ctattgatgt agcggtcttt
    33721 taagttggtc agttccaaat agttcagagt ttctcggatt ttttcccagt cttctgatct
    33781 aagtcgacct cggctgtagg gaaaacgtcc aaaactgacc agttcttcaa cagtcaattt
    33841 ggcttggtaa ttgattttct gttttaggat ggttagttct tgagccagtt cttgcgaatt
    33901 ccagctctcg atttcacgtc ctttgatact gagaactccc tgatctttct tggttagtct
    33961 gctcatgatg gagaggagag tcgattttcc agcaccattt ggaccaataa aggctgtcag
    34021 tttttgagga ctgacttcaa gcgaaatgcc ttgcaaaata tcctgttttt gaatggattt
    34081 gtcaatgttt tccagtttca ctgacgagcc ctcctatata gtaagataaa gaataagaag
    34141 ccacccacac tctcaatgat catactgata cgaatttcca gtgcaaagac tcgttcaatt
    34201 aaggcttgcc ccaaggttaa gctaataaat ccaaccagaa tggccactat aaagagtaac
    34261 ttgtgctgat agtctttgac aatcaggtag gtgaggttgg ccagcataaa gctgaagaag
    34321 gccataggtc ctaccaaggc agtggccgtt gaggtcaaaa gcacgattcc ccagagtaac
    34381 tctttctgtt ctttttcaac atcgagtccc aatatctgag ccgtttctct ttgcaggtgc
    34441 aagacatcta gaacgactgc ttttcgaaag aaaaagattg tcaaagcgag gatgatcaga
    34501 gaaccgatgg ctaggatgga agtgttgaga tgttgaaagg aggcaaaaag actattttgc
    34561 agtttatcgt attcgtttgg atccattagg acttgaagga aggtgctgat atttcgaaag
    34621 agacttctga gcgctagaca gatcagcagg acgaagacca ggtcttgctt catcagtgtc
    34681 ttcaagtaac cttgtaaggc gagaaagaag agggactgga caagaagtaa gactaggaat
    34741 tctaagatag gggatttgcc aagttgaaga aacttgcttt caaaaaccag tagtagggtt
    34801 tgtagtagga cgtagaagga ttcaattccc aaaatactag gcgtcaggaa gcgattttcc
    34861 gtcagggttt gaaaactaat ggtcgaaatc ccagtcgcga tggctaccaa gagataaacg
    34921 atgatctttt gggaacgcaa cttccaagca aaggctgaca agtgagtgat gggccaaaag
    34981 tagagaagac aagctccgat ggcaagaata atgagaatcc agaagagctt ggtatgtttg
    35041 cttttagtct gcatcttttc gtccccctct ccagagaagt aggataaaga cgagactacc
    35101 gatgattcct agcaagagac tgacagacaa ctcatagggc ctaatcagaa ctcgggatag
    35161 gatatcgcaa gccagaacta gattggcacc aaccagtgcg accatgagtt tggtttgact
    35221 tagattatct ccatagcgct tgcgaacaag attgggaacg ataactccga gaaatggtag
    35281 gtcacccacg gtaatcatgg tgacgcttgt cgttagcgcc accagaaaga gggccagttt
    35341 ttcaagtagg gagtaggaaa tccccaaact ctcgctggtt tctttcccta gattcatgat
    35401 ggtgaaggtt tgggataatt tccaaacggt tatcaggatg atgaggccta agaagagcca
    35461 ctcatactga tgggtctgaa tcatggagaa ggagccctgg gtccaggcag tcatactctg
    35521 aaccagattg aaacgatagg cgataacttc tgtgactgag ccgataatcc cgctatagat
    35581 gatcccaatc agaggcaaca tccacctttc ctttacagta aaaatggtca taaaggctag
    35641 gaagaagagg gtgaatacga tggatgaaac aaaagcgaag agcatctttt gggtcagact
    35701 agccgatgga aagacaaaaa ggctcagcac cattcccagt ttggcggctt cagtcgttcc
    35761 aactgtactc ggtgcagcaa actgattttg ggtaatagtc tgcatgagaa ggcctgccat
    35821 actcatacta gaggcagtca ggagaatact gatagttctt gggagacggg actcttgaaa
    35881 gaggagccag gtctgctggt cgaaatcaaa tagctttccc catgaaaaat cactggtccc
    35941 aatgctaata gagagaaaga ctaggagtag aagtaagcca attaaataat gagaaagttt
    36001 cataccccgt cctttcatgt agatttggta tcgaaagata tctgcggata taaatgtaac
    36061 attatttttc taatctgtca ataaaatttc tgacaattta ataaatacaa caaggagaga
    36121 gcaacaagac tttctccttt gttatcctat tctaaaatgt ttttacctta atctgataaa
    36181 ataatatctt cgagggagta gctagccgtc caatcaagat attgtttagc ttttgaagca
    36241 tctgctagga cactggctgg gtcactagca cgtcgagcaa caatctcgtg tgggattttt
    36301 taatttagta attcttcagc agttttaaag atttctttga tagtatagcc ttttttagtt
    36361 cctaagttaa agatttgaga agaactgtct tcttgaaata ggtagttcat tcctttaaca
    36421 tgagcctatg caaggtccaa gacataaatg taatctcgaa tacatgaacc gtcacgtgta
    36481 tcgtagtcat ctccaaatat ttttaagcta tcatgttgtc ccaatgcggt cttgttgata
    36541 tttggaatga tgtgagttgg atttttcaca cgcagaccgt ttgaagcatc catttcagcc
    36601 ccagcaacat taaagtaacg gaaaataaca tatttccagt cgtagcgatt ggccatccag
    36661 taaatcattc gttcgcccat cagttttgtc tctgcataag ggttgacagg gtcgagcagg
    36721 gtatcttcag tcaccggctt gtcaatacag ttatttccac agagagaagc agtcgaagag
    36781 aacatgattt tttgaatgcc aacttcagat aagactttga gaacttggtt cataccagca
    36841 acgttggtag tgaagtattt acttggattt tcaatacttt cgctcacaac aatttcacct
    36901 gcacaatgga ggacagcatc aatctgattt tcttctaagt aagcctttaa ggcgctagca
    36961 tcataaacat ccagttcttt aaagctagca tgactatcca cagccgctcg atttcctgtg
    37021 gagagattat cgaggacatg cacctgatag ccagcattta aaagagcttt aacggtatgg
    37081 gagccaatgt agctagtccc acctgtaaca agaattgttt tggtcatgat tttttccttt
    37141 tctagttttg tactatagta aattgaaata agatatgaac aactctatta ggaaagtcaa
    37201 attaatttct agaaatgttt cagcagctac agcgtactat tccaaactca accaactata
    37261 tatttaaaga aagaagaaag ggaagtcaac tattttctgt aaatttcatg aaaaatccaa
    37321 acaactttga tggtgtattg tttttttgtt tggaaataaa tattcgagtt aattttggaa
    37381 tgtttactag attttgcact acatgcaaga gaatactatc cttttctaag atagagcagg
    37441 actaagatac taacttagaa atccaccttc ccactatcct tctcctataa aaagtggtaa
    37501 aatggatgaa agaaagaagg aactgaaatg acaacattat tttcaaaaat taaagaagta
    37561 acagaacttg ctgcagtctc aggtcatgaa gcgcctgtcc gtgcttatct tcgtgaaaag
    37621 ttgacaccgc atgtggatga agtggtgaca gatggcttgg gtggtatttt tggtatcaaa
    37681 cattcagaag ctgtggatgc accgcgcgtc ttggtcgctt ctcatatgga cgaagttggt
    37741 tttatggtca gcgaaatcaa gccagatggt accttccgtg tcgtagaaat cggtggctgg
    37801 aaccccatgg tggttagcag ccaacgtttc aaactcttga ctcgtgatgg tcatgaaatt
    37861 cctgtgattt caggttctgt tcctccgcat ttgactcgtg gaaagggggg accaaccatg
    37921 ccagccattg ccgatatcgt ttttgatggt ggttttgcgg acaaggctga ggcagaaagt
    37981 tttggcatcc gtcctggtga taccatcgta ccagatagtt ctgcaatttt gacagccaat
    38041 gaaaaaaata tcatctcaaa agcttgggat aaccgctacg gtgtcctcat ggtaagcgag
    38101 ctagctgaag ctttatcagg tcaaaaactc ggcaatgaac tctatctggg ttctaacgtc
    38161 caagaagaag ttggtctgcg tggcgctcat acctctacaa ccaagtttga cccagaagtc
    38221 ttcctcgcag ttgattgctc accagcaggt gatgtctacg gtggtcaagg caagattgga
    38281 gatggaacct tgattcgttt ctatgatcca ggtcacttgc ttctcccagg gatgaaggat
    38341 ttccttttga caacggctga agaagctggt atcaagtacc aatactactg tggtaaaggc
    38401 ggaacagatg caggtgcagc tcatctgaaa aatggtggtg tcccatcaac aactatcggt
    38461 gtctgcgctc gttatatcca ttctcaccaa accctctatg caatggatga cttcctagaa
    38521 gcgcaagctt tcttacaagc cttggtgaag aaattggatc gttcaacggt tgatttgatt
    38581 aaacattatt aaaccataag ggaggtggta gggatggcag aaccaaacct agaaagcctt
    38641 ataaaagatc tttacaatca tgctcgacat gatttgagtg aagatttagt tgctgctctc
    38701 ctagagacta ctaaaaaact acctactaca aatgagcaat tgcaggcagt tcgtctctca
    38761 ggcctggtca atcgtgaatt gctcctaaat cccaaacatc cagcacctga gttgctcaac
    38821 ttggctcgct ttatcaaaag agaagaagcc aagtacagag gaactgcgac ttctgcgctt
    38881 atgtatgagg aactctttaa aatgctttga ttccattgtg gatcaaagca ttttttgtaa
    38941 gatctatctc gtgagcgttc aaatagtagt aacaaggaat catgagaagt cagccgagcc
    39001 catagtagtg aagaaacttc tgtaatggaa gtggagcgaa gtgaggaatc gtcaaacggt
    39061 aggggatagg ctgtttgaag ggtgctacga aaaagatagg gtaaggtgaa attatagcgg
    39121 aatgaaataa gatatgaaca aattgattga ggaaattaaa tgaatttata gaaatctttt
    39181 agcagtcatg gtgtcctatt ccagtttcga aatgctataa atacgaacaa attgattggg
    39241 aaattcaaat cgctttctat caatgtttta gaagatacag tgctctagtc taacttcaat
    39301 atactataaa agaacagatg gaagcaatta tgatttactt ctatctttaa aataaatggt
    39361 ctgataggaa aaatgtgtcc cctcataaaa tataggatag tacgaatgga aggcttttgt
    39421 agactggagg acgaaggagt ttagaaactc tcgttaaaag ttagttgagc cggagtatgg
    39481 tggtgtggat aattatcaaa aattatttct aaatcgaaat agttgacagt tagaacgatg
    39541 agtgttacaa ttgttttatt catttcgata tcgaaataaa ttggaggtgt tatgaaagat
    39601 ggtcatttgc tagcccatca tattcgtttg ttgaatgggc ggatttttca aaagttactg
    39661 agtcaagatc ctgaggctct ttataggggt gaacagggca agattttagc ggttttatgg
    39721 aatagtgaaa ctggctgcgc aactgcgaca gatatcgcgc ttgcgactgg acttgcgaat
    39781 aatacgctga cgactatgat aaaaaagcta gaggaacaaa agcttgtaat tgttagtccg
    39841 tgtggaaaag acaagcgtaa gaagtattta gttttaacgg agttaggcaa gtcccagaaa
    39901 gaagtggggc atcgtgtcag tcagaaattg gatactatct tttacaaagg attttcagag
    39961 gaagaaattc accaatttga aggttttcaa gaaagaattt tggcgaatct gaaagagaag
    40021 ggaaatgagg tttagaatat gtcacaacaa gtgaaaaatg ctcacaacct atacatccat
    40081 gccattcaag acggacgagt tgctgaggct caagcccagt ctgtagggga tacctatatc
    40141 caacattcga caggtgttcc tgacgggaaa gaaggatttg cagccttctt tgcagatttc
    40201 tttgagcgtc atccagagcg tcagattaag attgtccgca ccattgagga tggcaatctg
    40261 gtctttgttc atgttcatca atatctgaat ggtggagaag ctcaatgggt gacgacggat
    40321 actttccgtg cggatgagaa tggtcgtatt gttgagcatt gggatgtcat tgactactat
    40381 cgaacacctg aaaatgacca actagatcaa atttttggag attttgaaat caaggatttg
    40441 gacaagaaag cagaaaataa aaagctggtt cgccgtttct tgacagaaat tttccaaaat
    40501 ggggagctag agcagtggag tgattatgtg gcagacgatt tgattcagca taatcatgat
    40561 attggacaag gaagtgctgc ttataaaaac tatgtggctg aatatagtgt cacttttgac
    40621 tttgttttcc aactcttagg acaaggaaac tatgtggtta gctatggtca gactcagatt
    40681 gatggcgttg cttatgccca gtacgatatc ttccgtttag agaacgggaa aattgtggag
    40741 cattgggata ataaggaagt catgcctaag gtagaagact tgaccaatcg agggaagttt
    40801 taaattgagg acaaagaatg attgaataca aaaatgtagc actgcgctac acagaaaagg
    40861 atgtcttgag agatgtcaac ttacagattg aggatgggga atttatggtt ttagtagggc
    40921 cttctgggtc aggtaagacg accatgctca agatgattaa ccgtcttttg gaaccaactg
    40981 atggaaatat ttatatggat gggaagcgca tcaaagacta tgatgagcgt gaacttcgtc
    41041 tttctactgg ttatgtttta caggctattg ctctttttcc aaatctaaca gttgcggaaa
    41101 atattgctct cattcctgaa atgaaggggt ggagcaagga agaaattacg aagaaaacag
    41161 aagagctttt ggctaaggtt ggtttaccag tagccgagta tgggcatcgc ttacctagtg
    41221 aattatctgg tggagaacag caacgggtcg gtattgtccg agctatgatt ggtcagccca
    41281 agattttcct catggatgaa cccttttcgg ccttggatgc tatttcgaga aaacagttgc
    41341 aggttctgac aaaagaattg cataaagagt ttgggatgac aacgattttt gtaacccatg
    41401 atacggatga agccttgaag ttggcggacc gtattgctgt cttgcaggat ggagaaattc
    41461 gccaggtagc gaatcccgag acaattttaa aagcgcctgc aacagacttt gtagcagact
    41521 tgtttggagg tagtgttcat gactaattta attgcaactt ttcaggatcg ttttagtgat
    41581 tggttgacag ctctatctca acatttgcag ttgtcacttt tgaccttgtt actagctatt
    41641 ttgcttgcga ttcccttggc tgtttttctt cgctatcatg agaagctggc cgactgggtc
    41701 ttgcagattg caggtatttt ccagaccatc ccgtctctgg ccttgttggg actctttatt
    41761 cccttgatgg gaattgggac tttaccggca ttgacagctc tagtgattta tgcgattttt
    41821 ccgattttac aaaatactat tactgggctg aagggaattg atccgagtct tcaagaggct
    41881 gggattgcct ttgggatgac cagatgggag cgtctcaaga agtttgaaat tccacttgcc
    41941 atgcctgtta tcatgtctgg aattcggacg gcagcggtct tgattatcgg tacggctacc
    42001 ttggcgacct tgattggggc agggggactg ggttccttta tcctgttggg aattgaccgt
    42061 aataatgcca gtttgatttt gattggggcc ctttcttctg cagtgctagc tattgccttt
    42121 aacttcctac taaaagtaat ggaaaaagcg aaattgcgga cgattttctc tggttttgcc
    42181 ttggtggctt tattactggg tctgtcttat agtccagccc ttttggctca aaaagagaag
    42241 gaaaacgtga ttattgctgg gaaaataggc ccagaaccag aaattttggc taatatgtat
    42301 aaattgctga ttgaagaaaa taccagcatg actgcgactg ttaaaccgaa ttttgggacg
    42361 acaagtttcc tttatgaagc tctgaaaaaa ggtgatattg acatttatcc tgaatttacc
    42421 ggtacggtga ctgaaagttt gcttcaacca tcacccaagg tgagtcatga gccagagcag
    42481 gtttatcaag tggcgcgtga tggcattgcc aagcaggatc atctagccta tctcaaacct
    42541 atgtcttatc aaaataccta tgctgtagct gttccgaaaa agattgctca agaatatggc
    42601 ttgaagacca tttcggattt gaaaaaagtg gaagggcagc tgaaggcagg ctttacgctt
    42661 gagtttaacg accgtgaaga tggaaataag ggcttgcaat caatgtatgg tctcaatctc
    42721 aatgtggcga ctatgcagcc agctcttcgt tatcaggcaa ttcagtcagg ggatattcaa
    42781 atcacggatg cctattcgac tgatgcggaa ttggagcgtt atgatttaca ggtcttggaa
    42841 gatgacaagc aactcttccc accttatcaa ggggctccac tcatgaaaga agctcttctc
    42901 aagaaacacc cagagttgga aagagttctt aatacattgg ctggtaagat tacagaaagc
    42961 cagatgagcc agctcaacta ccaagtcggt gttgaaggca agtcagcaaa gcaagtagcc
    43021 aaggagtttc tccaagaaca aggtttgttg aagaaatgat gggacagaga ctttaaacat
    43081 actgaactca acttccttaa acgactagat aaaagaatgc tcagacaatt tcgtctgggc
    43141 ttt
//
LOCUS       DBERXF010000016        39915 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.16, whole genome shotgun sequence.
ACCESSION   DBERXF010000016 DBERXF010000000
VERSION     DBERXF010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 39915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39915
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.16"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..2465)
                     /gene="pbp1b"
                     /locus_tag="ACL8JK_000958"
     CDS             complement(<1..2465)
                     /gene="pbp1b"
                     /locus_tag="ACL8JK_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HGS1785859.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVSPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            2607..3863
                     /gene="tyrS"
                     /locus_tag="ACL8JK_000959"
     CDS             2607..3863
                     /gene="tyrS"
                     /locus_tag="ACL8JK_000959"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGS1785860.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(3941..6004)
                     /locus_tag="ACL8JK_000960"
     CDS             complement(3941..6004)
                     /locus_tag="ACL8JK_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGS1785861.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTTTDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(6006..6284)
                     /locus_tag="ACL8JK_000961"
     CDS             complement(6006..6284)
                     /locus_tag="ACL8JK_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HGS1785862.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            6436..7284
                     /locus_tag="ACL8JK_000962"
     CDS             6436..7284
                     /locus_tag="ACL8JK_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HGS1785863.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTESHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            7907..8479
                     /locus_tag="ACL8JK_000963"
     CDS             7907..8479
                     /locus_tag="ACL8JK_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785864.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(9524..11782)
                     /gene="glgP"
                     /locus_tag="ACL8JK_000964"
     CDS             complement(9524..11782)
                     /gene="glgP"
                     /locus_tag="ACL8JK_000964"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HGS1785865.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGENSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11808..13340)
                     /gene="malQ"
                     /locus_tag="ACL8JK_000965"
                     /pseudo
     CDS             complement(11808..13340)
                     /gene="malQ"
                     /locus_tag="ACL8JK_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
     gene            13875..15146
                     /locus_tag="ACL8JK_000966"
     CDS             13875..15146
                     /locus_tag="ACL8JK_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS1785866.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            15257..16549
                     /locus_tag="ACL8JK_000967"
     CDS             15257..16549
                     /locus_tag="ACL8JK_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGS1785867.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            16551..17393
                     /locus_tag="ACL8JK_000968"
     CDS             16551..17393
                     /locus_tag="ACL8JK_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGS1785868.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            17646..18446
                     /locus_tag="ACL8JK_000969"
     CDS             17646..18446
                     /locus_tag="ACL8JK_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGS1785869.1"
                     /translation="MLPYPFSFFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTVSQASSIVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            18456..19442
                     /locus_tag="ACL8JK_000970"
     CDS             18456..19442
                     /locus_tag="ACL8JK_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1785870.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            19584..19736
                     /locus_tag="ACL8JK_000971"
     CDS             19584..19736
                     /locus_tag="ACL8JK_000971"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785871.1"
                     /translation="MKIKVQTRKLAAGCSKHCFEVVDETDEVSSKHGFEVADRTDEVS
                     NIYTAR"
     gene            complement(19778..20719)
                     /locus_tag="ACL8JK_000972"
     CDS             complement(19778..20719)
                     /locus_tag="ACL8JK_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGS1785872.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(20697..22460)
                     /gene="aspS"
                     /locus_tag="ACL8JK_000973"
     CDS             complement(20697..22460)
                     /gene="aspS"
                     /locus_tag="ACL8JK_000973"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGS1785873.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
     gene            complement(22611..22814)
                     /locus_tag="ACL8JK_000974"
     CDS             complement(22611..22814)
                     /locus_tag="ACL8JK_000974"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785874.1"
                     /translation="MKIKEQTRKLTAGCSKHCFEVVDETDEVSSKHGFEIVDETDEVS
                     SKHGFEVVDETDEVSNRTTVRRR"
     gene            complement(22856..23086)
                     /locus_tag="ACL8JK_000975"
     CDS             complement(22856..23086)
                     /locus_tag="ACL8JK_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785875.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(23104..23745)
                     /locus_tag="ACL8JK_000976"
     CDS             complement(23104..23745)
                     /locus_tag="ACL8JK_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS1785876.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRPLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(23757..24491)
                     /locus_tag="ACL8JK_000977"
     CDS             complement(23757..24491)
                     /locus_tag="ACL8JK_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HGS1785877.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIILSFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(24494..24691)
                     /locus_tag="ACL8JK_000978"
     CDS             complement(24494..24691)
                     /locus_tag="ACL8JK_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785878.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(24691..24897)
                     /locus_tag="ACL8JK_000979"
     CDS             complement(24691..24897)
                     /locus_tag="ACL8JK_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1785879.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(24907..25374)
                     /locus_tag="ACL8JK_000980"
     CDS             complement(24907..25374)
                     /locus_tag="ACL8JK_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785880.1"
                     /translation="MIDKVVRNLLLTFFFCKMTKIINFLTTIIVKKKKMCYNEFKLRN
                     RKQKGVIMWVLVFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRLLQEMIGK
                     EPIITGVYIGPDNWEVVDVDEEWVKLRSVDKKGKEKFKLQRIEDIQTVEFDGE"
     gene            complement(25374..25610)
                     /locus_tag="ACL8JK_000981"
     CDS             complement(25374..25610)
                     /locus_tag="ACL8JK_000981"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785881.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSSKHGFEVVDETDEVS
                     SKYCFEVVDRTDEVSNHTYGKVKLTWFEEILEEY"
     gene            complement(25607..26896)
                     /gene="hisS"
                     /locus_tag="ACL8JK_000982"
     CDS             complement(25607..26896)
                     /gene="hisS"
                     /locus_tag="ACL8JK_000982"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGS1785882.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(26974..28221)
                     /locus_tag="ACL8JK_000983"
     CDS             complement(26974..28221)
                     /locus_tag="ACL8JK_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HGS1785883.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKFSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLDLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(28412..29263)
                     /gene="rgg"
                     /locus_tag="ACL8JK_000984"
     CDS             complement(28412..29263)
                     /gene="rgg"
                     /locus_tag="ACL8JK_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HGS1785884.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            29387..29728
                     /locus_tag="ACL8JK_000985"
     CDS             29387..29728
                     /locus_tag="ACL8JK_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGS1785885.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            29792..29956
                     /locus_tag="ACL8JK_000986"
     CDS             29792..29956
                     /locus_tag="ACL8JK_000986"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785886.1"
                     /translation="MKIKGQTRKLAAGCSKHCFEVMDRTDEVSPKHCFEVVDRTDEVS
                     NHTYGKATLT"
     gene            complement(29982..31685)
                     /gene="ilvD"
                     /locus_tag="ACL8JK_000987"
     CDS             complement(29982..31685)
                     /gene="ilvD"
                     /locus_tag="ACL8JK_000987"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HGS1785887.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIIDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(31918..32850)
                     /locus_tag="ACL8JK_000988"
     CDS             complement(31918..32850)
                     /locus_tag="ACL8JK_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HGS1785888.1"
                     /translation="MMRSTKELRYVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFSSRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPEAVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(32847..33704)
                     /locus_tag="ACL8JK_000989"
     CDS             complement(32847..33704)
                     /locus_tag="ACL8JK_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGS1785889.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(33708..35054)
                     /locus_tag="ACL8JK_000990"
     CDS             complement(33708..35054)
                     /locus_tag="ACL8JK_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS1785890.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(35067..35351)
                     /locus_tag="ACL8JK_000991"
     CDS             complement(35067..35351)
                     /locus_tag="ACL8JK_000991"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1785891.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(35355..37385)
                     /locus_tag="ACL8JK_000992"
     CDS             complement(35355..37385)
                     /locus_tag="ACL8JK_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS1785892.1"
                     /translation="MFDYRALVILMTLMDHCEVSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYNDIKMIIKQED"
     gene            37577..38584
                     /locus_tag="ACL8JK_000993"
     CDS             37577..38584
                     /locus_tag="ACL8JK_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGS1785893.1"
                     /translation="MTEKLINSKPNGVFALILIELTLVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            38587..38787
                     /locus_tag="ACL8JK_000994"
     CDS             38587..38787
                     /locus_tag="ACL8JK_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS1785894.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            38939..39121
                     /gene="rpmF"
                     /locus_tag="ACL8JK_000995"
     CDS             38939..39121
                     /gene="rpmF"
                     /locus_tag="ACL8JK_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGS1785895.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            39137..39286
                     /gene="rpmG"
                     /locus_tag="ACL8JK_000996"
     CDS             39137..39286
                     /gene="rpmG"
                     /locus_tag="ACL8JK_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS1785896.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(39778..>39915)
                     /locus_tag="ACL8JK_000997"
     CDS             complement(39778..>39915)
                     /locus_tag="ACL8JK_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785897.1"
                     /translation="ESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV
                     G"
BASE COUNT        12403 a         8589 c         7090 g        11833 t
ORIGIN      
        1 tatcgtctcg cccttgaaga agaaggtcgt gtagtacttg agttactgct atcgctagaa
       61 ctactacttg aactgctgga gctggatgga gttggtagac tccccacaat actagaccaa
      121 gcattctgat aatccgcatc acttccgcca atagcaaagc gataacttgt cgctggcgct
      181 cctgacttat tagcccaata gctggtaaca gtcgaacctg tgacctctac ttcttttcct
      241 tcaacagaaa ccttccctgg tttttgacct gttgatttca agacttccga tttcactaca
      301 ctaggatcta aagcaaagcg ctcgttcccc caaatgcttg gggaagcttg ctgaatcgca
      361 tttaccagat gagccatgta attagagtta ttagaataac ctgctctacg tgacaatgaa
      421 tgattatcat catgcccaat ccagccacct agggttaatc taggtgtcga aagcatgagc
      481 cacatatttt cgtcttggtt ggttgtacca gtcttcccaa tccaatctgc attagccaga
      541 gtaggattta aagaagtcag gttagacttg aaggttgttg tcacacgaga ggatagaact
      601 tctcgtagca atccctgcat aatcgtcgca gtagcttttg aatagacttg aaccggttta
      661 tcctgatact catacaccac tctaccatct gctgcttcaa tctttgaaat cacatgcttc
      721 tgatgataaa ctccattatt agctaaggtc tgatagccat tggtatgctg ggcaactgtg
      781 acttcaatac caccacccat tggcaagctc tcaataccgt actcaggaat ctcgtaaccc
      841 atcttttcca tataaccctt gacatcaaca cccttttcac ggagcatacg ataggtccag
      901 taagcaggga tattccatga atagttcaga gcttctccca aggtcatcat tcctgttccc
      961 ttgctattag catacataat cggattgcca ttagcaaagt ttgttggata gttagataga
     1021 atcgtttcac ttcccatcaa gccctggtca atagcaatac cgtaggccag caagggcttg
     1081 gtagtagaag ctggcgaacg tttggtatca aaggcatgat tattttgatt ttcttgataa
     1141 ttacgaccac ctacaaagcc tagaatagca cctgtttggt tatccatcaa gacattccct
     1201 acttctacac gacctgttcc atcgtctaaa agatagccat aatcagcaac cgcactttgc
     1261 atggcagaat gaattttctg atctatggta gtagtaatct tataaccacc attttcaatt
     1321 tccttggctg ccaaatctcg ataaaacttc tgagttgcct catttttcaa ctccttagcg
     1381 gagacattgt ctctctgagc tagatagtca tacatacgtt cttgagcttc tgccaaagtt
     1441 gtaaagtata aatagtctcg tgaaattcct gtaaccgtgc ccgatggtaa aaagtcctgt
     1501 ttaaggtcat aatccttgta ctgagaatac tcgtctttgc ttaatgcacc tgtacgatac
     1561 atactgtaaa gaactgcctt agcccgtctt aagccaattt ctaggtcttc atcactcttc
     1621 aactccccag tattttcata aggagagtaa gtaatgggac tctgtggaag tcctgctaaa
     1681 aatgctgctt gaggaacagt caactgactg gcatctacac cgaaaattcc ctcagctgct
     1741 tgccgagccc ctgcaatatt ctgtccctta ttatttcggc caaagggaga cacattgaga
     1801 taggtcgtta aaatctcatc tttattcatg gcgcgttcca aggcaagagc atccacaatc
     1861 tctgccgcct tacgagccaa ggtcggcgca tccccaacca cctgctgttt aattagttgc
     1921 tgggtcaagg ttgaaccccc actagaggaa cccaaaccta caaatttccc caaggtcgca
     1981 cgaatcaccg ccttgggtac tacaccctta tgttctttaa agtgttcatc ttctgtcgca
     2041 atgatagcct tcttcagatt ttccgaaatt tgctcagatg agatagaagt gcgcaacaaa
     2101 tcactctcta tggaagcaat caccgtcccg tccgaatagg taatctctga aatagaagag
     2161 atgtccttga cctgattcac caattcttct gtctgaggca cccgaacctt gtcaaataag
     2221 gccactccgt accccaaagc aatcccaact cccaacattc ctcctagaaa accgagtaca
     2281 aagagtaagt taaataaggc ttttatactc agtaaaatag ctgggaaaat ggctgactta
     2341 tctaaggttt tagatttttt ggtacttgaa cctttcttgc caggtctagc tgatttttta
     2401 tttttttgtt tttgctggaa aaattccagc atttttcgtt ttaattcatt taattgattt
     2461 tgcatggatt tcctcactct atctattata ccacaaaagg gaaattttca ataaaatagc
     2521 cactttcttc cctattctgc taggctattg cccaagtttg tgatacaata ggtagaaaca
     2581 ataattttaa aaaggagaaa agacacatgc acatttttga tgagctaaaa gagcgtggtt
     2641 tgatatttca aacgactgat gaagaagctt tgcgtaaagc cctagaagaa ggtcaagttt
     2701 cttattatac tggctacgat ccaactgctg acagccttca cctaggccac cttgtcgcaa
     2761 tcttgacaag tcgtcgcttg caactagcag gtcacaaacc ttatgcgctc gttggcggtg
     2821 ctacaggtct catcggagat ccgtccttca aagatgctga acgtagtctc caaacaaaag
     2881 acacagtaga tggctgggtc aagtctatcc aaggacaact ttctcgtttt cttgactttg
     2941 aaaatggcga aaacaaggct gtcatggtca acaactacga ctggtttggc agcatcagct
     3001 tcattgactt cctccgtgat attggaaaat acttcacggt caactacatg atgagtaagg
     3061 aatctgttaa aaaacggatc gaaacaggaa tttcttacac tgagttcgct taccaaatca
     3121 tgcaagggta cgacttcttc gtccttaacc aagaccataa tgtcactctt caaatcggtg
     3181 gttctgacca gtggggaaat atgacagctg gtaccgaatt gcttcgtcgt aaggcggaca
     3241 agactggtca cgttatcact gttccactaa tcacagatgc aactggtaag aaatttggta
     3301 aatcagaagg aaatgccgta tggctcaatc ccgaaaagac ttctccatac gaaatgtacc
     3361 aattctggat gaacgtgatg gacgctgacg ctgttcgctt cttgaaaatc tttactttct
     3421 tgtcacttga tgagattgaa gatattcgta aacaatttga agcagcgcca cacgaacgct
     3481 tggctcaaaa agtcttggct cgtgaagttg ttacacttgt tcacggagaa gaagcctaca
     3541 aagaagcact taacatcact gagcaactct ttgcaggaaa catcaaaaac ctttctgtca
     3601 aagagctcaa acaaggactt cgtggtgtgc caaactacca agtacaggca gacgaacata
     3661 acaatatcgt ggaactgctc gtctcatctg gtatagttaa ctcaaaacgc caagcccgtg
     3721 aagacgtcca aaacggagcc atctacgtaa acggcgaccg catccaagac cttgactatg
     3781 tcttgagtga cgctgataag ttagaaaatg aactgactgt tatccgtcgt gggaagaaaa
     3841 aatactttgt attgacttac taaactattc aacatttatc tataaacaaa ggagttaacc
     3901 tcgagaaagg taactccttt ttgctgttaa taactctcat ctatctattt ttaatagaca
     3961 agctacgcaa gacaatgcgc aaggttgtta gattatgtaa gatagagaga tttgaaggac
     4021 tgaaccaatt aaataagcca aagccaatca aactactatt tacgacaacg gtatcttgaa
     4081 tatttttctt gatgagtgtt tgcaaagatg atgataacga atccaactct tggaagaaat
     4141 ccaaacgatt atctaacaat aagatatcac tcatctgctt agaaatatct gcactctcat
     4201 tcatcaccac accgatatct gatagagtta aagccgctga gtcattcaat ccatctccaa
     4261 ccatcaaaat agtgtgacct gctttctgca gtttctctac taactcaaat ttcccatcag
     4321 gtttcaagtc tgtatagacc tgatcaaagg gcaaatcttt gactaattcc tctgtcctaa
     4381 tcaaggtgtc tcctgttgcc agaattaatt ttttcccctg tgccttaagt ttatccaagg
     4441 ctgtttttgc ttcttttctc aaaggagtat gaatgcagaa cattccaatc aattcatttt
     4501 gataagccaa gaataagaga ttgtagtgac tcttgtactc ttcaattaaa gcattttgtt
     4561 ctgaactgat atgaatctgc tcatcctgca tcaagacata attcccaata agaactggtt
     4621 ggccatctat atgagatttg atccccttgc ttgcgatata ttggagtttc ccatgcattt
     4681 cctcatgttc aattccctct atctcagctt gcttgacgat ggcattagca ataggatgat
     4741 aaatgtgttc ctcaagacag gcactgattc tgagaatatc ttcctcacta tagtctccaa
     4801 aaggtaacac cttttcaact ataggataac tagttgtgat tgttcctgtc ttatcaaaca
     4861 agaaagtatc aacttccaga tatttctcca gaacatctcc atccttaatc accatttcac
     4921 ggttcaaccc ttccttgata actgtcaaat aagctacagg agtagagatt ttcaaagcgc
     4981 aggagaaatc gaccaatagg aaagaaatag ccttagaaaa agaacctgtc aataggtaag
     5041 tcagcccagc ccccaagaaa ttatatttga cgactttatc cgccatcttg atgaaatagc
     5101 gttgtttcgt tttcttgttt tcttcagatt tcttcatcaa ctcaatcagc tgtaaaatac
     5161 ggctgttcat ctgattatct gttacacgaa tgcgtaactc tccagtttct aatactgtat
     5221 ttgcacaaac caaatcagac tctctttttt caactggaaa actctctcct gtcaaggaac
     5281 tttcgttgac catacctaaa cctgaaacta cttgcccatc aaacagaatt tcatttcctt
     5341 gagataagat caagacatct cctatttgaa catcggaact ctttatacta acaaccgtat
     5401 cgccctgtac taggaataca tcgctctctt ttgcaagaag actctgttct aaatctgttg
     5461 tagttttttt caaggaccac tgatctaaat gattccccaa atcaagcata aacatgatat
     5521 tgctagctgt cttggattgg ttcataaaca aggacaataa aatagccgaa cagtccaaga
     5581 cttccatcgt tagttcctta cgcgctagtg tttgataggc ttctctaata taacccaaag
     5641 cctgataaca agtccatata tagcgaatag gatacggcac aaaactacga aaaagtacac
     5701 gcttaaccgc tgcacctgaa acaatagaat aagcactctc ttctctacga atgggaagag
     5761 tcatcaactc agaaactttc cctttatcaa ttctttttaa aaaggcttct gcattatcta
     5821 atacagaaaa gccttctttt atgcgtagag taaagtgctg ttgatccatg taaaactgga
     5881 tagactcaat ccccttttca tctctcgcca aggaacgaag atagtcttga atatccaagg
     5941 taagtgaaaa agaagatgat agtcggatat gttggtatcc tctatgtagc actttaaaag
     6001 acatattatt cacctataag gctatctaat tgctcttctt ttttctcttg ctcgtacaaa
     6061 tatttggcat cttgcaagac atcgtctcca tgttgcttca caacagaaac agatgcatct
     6121 agctcgtctt tcaacttgta agccttagcc aaagctttag aataaccttt tttagcttcc
     6181 ttacttgcta agattttcaa accaagggta ccaaatgcga caccacccaa aaataatgaa
     6241 gattttttcg caacttttgc aacggttaat acttctttta acatacttat ttcctcctta
     6301 tcattattat atagcaattt agatataaaa gcaatttcat tctataaatt ggagaattag
     6361 ttttatttct actgaatctc ccatctactt attcctaaag ttgctttcat ttgcctcttt
     6421 tgatacactt aaactatgaa tacaaatctc aagcccaaac ttcagcgttt tgcttctgcg
     6481 actgcctttg cctgtcctat ctgtcaagaa aatctgactc tgttagagac taatttcaag
     6541 tgctgcaacc gtcattcttt tgacttggcg aaatttggct atgtcaatct agcacctcaa
     6601 atcaagcaat ctgctaacta tgacaaagaa aattttcaaa accgtcaaca aatcctagaa
     6661 gccggctttt accaagctat cttagatgct gtatctgact tgcttgcaag ctcaaaaact
     6721 accacaacaa ttttggatat cggttgtggt gaaggattct attctcgcaa actacaagaa
     6781 agtcactctg aaaaaacttt ctatgccttt gacatctcca aagattcagt ccaaatcgct
     6841 gctaaaagtg aacccaactg ggcagtcaat tggttcgttg gcgacttggc acgacttcct
     6901 ataaaagacg ctaacatgga tattctgctt gatatcttct cacctgccaa ctatggagaa
     6961 tttcgtcgcg ttttatccaa agacggtatc ttgataaagg ttatcccaac tgaaagtcac
     7021 ctcaaagaaa tccgtcaaag agtacaggac cagctgacaa acaaggagta ttctaaccaa
     7081 gatatcaagg agcatttcca ggaacacttt accatcctat ctagtcaaac tgcctctctg
     7141 actaagacta tcacagcaga acaactccaa gccctactca gtatgactcc tctcctcttt
     7201 cacgttgacc agagcaagat tgactggagc caactgacag agattaccat cgaagcagag
     7261 attttggttg ggaaagcatt ctaaactaga cttcccaaag gtataaaact taccgaaaat
     7321 cttcaatatt acaaaaacgc ataagaacag gtacacaaac cttaatctta tgcgttttgt
     7381 tatagtttcc atacacatta aggggaaata gttgaaatca gttctcttaa taaccattga
     7441 ataccatata ctacatttac cccaaatatg atataggccg tataaatcaa gtatttcgat
     7501 ttctcccgtc tcaaagaata gatcttgtac aaaatagata aatttaaaat aataaataat
     7561 agagacaaaa tcttcctcca aaatcaatat taaaagtagc cagtcaatca tagttctaat
     7621 ctttattttc gattcgaaat tacaaactta tcaatgaaca ataagtgata taaggccagt
     7681 accagacccc aaacgctacc acgaaaagag aattcttgat gattgaaagt aaacaaatca
     7741 tggttaccaa tatagaggca ggtcaaaata acaaataaaa tccaaaataa atccgtccat
     7801 ttatattttt aaaaatattt ttttaacata atagcatatt tttcttgact ataataacag
     7861 tatataataa aatgtaagca gatacaaata aaaaggagaa aagctcatga acaaattaat
     7921 gaaatttatt tcggtttttt tgacgtcaat tgtgttaatt gtatcagcga ttccaagtgt
     7981 ttcagctgta tacgcttctg aacaagtatc acaaattgaa acaaatatgg aacttcaacc
     8041 tgtcacttct ctaacagaag aacaaatcaa tacacttgca aacgaaatcc aatcttttca
     8101 tccagacgtc tcacaacaat ggatcaaaga agtaattaac cgacaattac aaggcgatta
     8161 tacaatccca cctacatact ctccatttag agcagcttgg caaggtatta cagttaatca
     8221 aatgggtgct ctattagata ctgcaatagc tttagcatta ggaggaacta ctgcaggcct
     8281 tgcaaatcta attaaagtaa aaggaaaaca tgcagcaaaa agtgctattc gttcagcaat
     8341 ttctagatat ctaggtagtt ggtttgtaaa tgatgttgct ttagaatccg ctatgaattt
     8401 attatcaccg gggacttatt tagcacaatt atgggataaa aatgatgcca ttcctaacaa
     8461 cggaaggatt aacttttaat catgagatat acaataaaat taattgggta taacgtattt
     8521 tcgttgttta tattctttat cttatcaatg ttgtttaaag ttccctttag gtggtggatc
     8581 agcattgcaa tgacgacttc gtcgtacatt gtatataatt acttaaagaa aaagagagaa
     8641 aaggaatgat cttataccag atcattcctt ttctgctttc tgtaaatccc tcggagtgtg
     8701 tttggcgctt tgatacgaag tgtcaaagct gtataaacgt tactatttcc aaaaaagtaa
     8761 cagaaaattc ctgctttgta ggactgcttt gggtgagtaa tagacatgtc gactcaccct
     8821 atctcctgat ggcgaaaaga atttagcaat ggtgcaagtt gttctgaact cgagaaaaaa
     8881 catgccgaaa tcgaagaaaa gcatgcagaa cttgaagcga agaagcaaga aatgttgaag
     8941 cgcttggata aatagaattt agaaaacaga aaaaactaaa aagaatgtag ggtttatttc
     9001 cctacattct taaaataact tagtacataa atgacaatgc tgccactgcc gtcaatattg
     9061 caaaaactat tttccaaatt tttttatttt ttccaaaaat cttatcaggt aacaagctta
     9121 ttacaagaaa ggtaataaac aacaccaatt taagtgtgta tatcataaaa acaccttctt
     9181 tcctacaatt atattataat actttatgta agcgaataca agagatatga ggtaaccaac
     9241 tacgaaaaaa tataaggctg aagacagtaa aaaccagcat ttaaaacctt cactgtatct
     9301 aggatttccc tatttttaga caagattgac ccaaatccac agcatttaaa aaagcgaatt
     9361 tcaatcgaaa ctcgcttttt tacaaaatgt attagtataa atttgtatct tatactcaat
     9421 gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc tcaaagcacc gctttgaggt
     9481 tgcagataaa gctgacgtgg tttgaagaga ttttcgaaga gtattagttc aagtgccaga
     9541 tgtcttcgtt atactgagcg attgtacggt cagatgagaa gaatcctgct ttagaaatgt
     9601 taacgatgac tttatccaac catgcgtcac ggtcttcgta gtcagcaagc atttgctctt
     9661 tgactttgat gtagtcttcc aaatcaagaa gagtcatgaa ccagtctttg ttgatcaatt
     9721 cattgtaaag acgttccaag cgctctttgt ttccagctgc aagaactgca tcactaacga
     9781 tgaagtcaac caatggtttg atagcttcac gagcgtagaa ttcgcttgat ttgtaagctg
     9841 cttttgcgta aaggtcgata acagtttctg aattttcacc gaagatgtag atgttttctt
     9901 ctccaaccaa ctcagcgatt tccacgttag caccgtccat agtaccaagt gtcaaagctc
     9961 cgttcaacat gaatttcatg ttaccagtac ctgaagcttc tttagaagca agtgagattt
    10021 gttctgagat atcacatgct gggataagga aacttgctgc agtaacgttg tagttttcaa
    10081 ccataactac ttgcaagtgt ggagctactg ctggatcgtt agcaataact tctgacatgc
    10141 aaaggattaa atggataatg tcttgagcga ttgtgtaggc tggagctgct ttaccaccaa
    10201 agaagattgt gattggacga gcagggatgt taccagcttt gatgtcaagg tatttgtgga
    10261 tcacgtacaa agcgttcatt tgttggcgtt tgtactcgtg aagacgtttg atttggatat
    10321 caaagataga atttgaattg atttccacac cttggtgttc tttcaagtga cgagccaatt
    10381 tacgtttgtt gtgagccttg atgctttcca atttttcttt gacagctgct ttgtcttcat
    10441 aagacaacag tttttcaagc tcatctgctt catggtgcca accatctcca agaatctcat
    10501 ccaagtagtg agacaatctt gggttagcat gcataagcca acgacggaaa gtgataccgt
    10561 ttgttttgtt gttgaacttt tctgggtaaa ggtcgtagaa ggctttcaac tcagaatttt
    10621 tcaagatttc agtatgaagt gctgcaaccc cgttaacact gtatccgtag tggatatcca
    10681 tgtgagccat gtgaacacgt ccgctctcat cgatgatttg aacagctgga tctttgtact
    10741 ctgccttcac acgacggtcc aattcttcga tgattggtac caagtgagga accacttctt
    10801 gcaagaattc aagaggccat ttttcaagcg cctcagcaag gattgtgtgg ttagtgtagg
    10861 cagtcatgct acgaacaatt gagattgctt cgtcaagctc gataccacgt gcagtcaaaa
    10921 gacgaatcaa ttcaggaatc accattgatg ggtgagtatc gttgatttgg acaactgcgt
    10981 agtcagcaag gtcatgcaag ttgcttcctt tttcgattgc ttcgtcgatg atcaattgcg
    11041 caccgtttga aaccatgaag tattgttgga agatacggag caattcacct tgacggtcac
    11101 tatcatctgg gtaaaggaag agagtcaagt tgcgagcgat atctgtcttg tcaaagttga
    11161 taccatcttt aataatagaa gaatcaactg aatccaagtc aaacaaacgc aagcggtttt
    11221 tagtcgctgt ttcataacca gtaacatcaa tatcgtaaag agttgatgtc aaagtaaagt
    11281 ctgcaaatgg tacttggtag ctacggcttg agcgaaccaa ccagttttgc tctgtcaacc
    11341 atgcatttgg aattgtttct tgttggttgt ttttaagaac ttgttggaaa agaccaaagt
    11401 ggtagttaag accaacaccg tcaccattca aaccaagagt agcaattgag tcgataaagc
    11461 aggcagccaa acgtcccaaa ccaccattac caagagatgg ttccaattca acttcttcaa
    11521 cttcgatcaa gtctttacct gcagctgcaa gttctttttt aacatcgtcg taaagaccaa
    11581 ggttaatcaa gttgtttgac aagagtttac caatcaagaa ctcagctgag atgtagtaaa
    11641 cttttttctt accagtgttg actggttttt ggctgcttgc aagcttgctg tagttaagaa
    11701 gagcaaggta aagctcttca ttgctacatt ctgcaatggt tttattgtaa cgattttgta
    11761 caaattcttg tagtgataac atgtttagtt gtctcctgat tattgtctta tttctttaaa
    11821 tctaccaaat tttcattaat tcggcgataa attgttgtca agtcaagcaa accttcctcg
    11881 acagctggtg tcaattgatc ttcagtcata cgccaagacc agtttccacc aagggtagat
    11941 gggaagttca tacgagctgc ctcatccaat tctagtaaat cttgcatagt tgcaattgcc
    12001 ataaagctaa ctgatgaaaa tactgtacga agcatagcgt gtaccactgt ttcgtattct
    12061 ttacggttcg tgtaacgagc catgtactca cgagtcgcat catcaatctc attacggtac
    12121 caaccaagaa ccgtattgtt atcgtgtgtt cctgtgtaca taactgagtt agcaggtgcc
    12181 aagtgtgggc tatcaatgct ttcgtcttct gggttgaagg caaattgaag aatcttcatt
    12241 cctgggaagc cagtacgttc acgcaattcg atcacttcat ctgtcatgaa gccaaggtct
    12301 tctgcgatga tgtttagctc accaagttct tccttaacgg ctgcaaaaag cttgtagcct
    12361 ggacctttca cccactcacc aggtgctgct gtatcggaac cagcagggat ttcccagtaa
    12421 gattcgaagc cacggaagtg gtcgatacga acgatatcgt agattttgaa gctttcacgc
    12481 aagcgttcaa tccaccattt gtagccgtct ttgtccattg cttcccagtc atagattggg
    12541 ttaccccaaa gctgaccagt tacagaaaac tcatctggtg ggcatcctgc gatacaagta
    12601 gccttaccat tgacatctgt tttgaagaga tgtggatttg cccacatatc acttgaatct
    12661 tccgctacgt agattggcat gtccccaacg atttcgatgt ggttgtcgtt agcgtaagct
    12721 ttcaatttca accattgttg gaagaagaag tattgagtca cacggtggta aaccaacttg
    12781 tctgccaatt gctcacgata gctttcaagt gctgaagctt tacgagcacg agcatctgca
    12841 tctggccatt cagtccaagc aagattgtca aaatactctt tgatagccat atactcagca
    12901 aagagctcaa gccatgattg gttgtcttga gcaaatttct caaaatcttt aacatctccg
    12961 acttcaaaga aacgtttcac cgctttttct aaaagaggac gacgtgcata gtagatttta
    13021 gcatagtcaa cttcagacgc atcgctacca aagtcaactc cttcaaggtc acttgcttcc
    13081 aacaaacctt gctccaccaa gatatctaaa tcgataaaat gagtgtttcc tgcgaaggct
    13141 gagaaagatt ggtaaggaga atccccgtaa ctagttgctc ctaatggaag gatttgccag
    13201 taacgttgtt ttgtacggac caagaaatca acgaagtcgt aagcactttg accaaatgat
    13261 ccgattccgt aagctcctgg aagagaagag atgtgcatca acacaccact ttgacgtttt
    13321 ttcataatag cacctcgtgt gttaaaataa tggaacgttg cgtattttgc agacgcaaac
    13381 gtttgcgtta cttataagta tactcctttt caagcataat tgcaagcgtt tttaaaaaac
    13441 ttttttgatt atttttaagg agactaactc attttagcaa agataactta aaactatcta
    13501 atcctaaagt ttgactctca cgagacagtc tacaaagtac aaaacctcct tagggagctt
    13561 gaatttatat gcaacaaagc acaaacgtct atagaaaata gatagggatt agaaacaggg
    13621 aggtagcccc tcctgatttc cctctttaga cagattccat atatttttat taaaaatact
    13681 gtattcttat ctatttcata cttttcttct attaaaatgc aaaattatgc tatcaaatca
    13741 agcttaaaaa ttttttaaaa tttttacaaa aaatacttgc aaccgttttc tatttgtgct
    13801 atactaagct cataaaggaa aacgtttgcg tttccttatc aataaaactt gctattcttt
    13861 gggaggaata cactatgtca tctaaattta tgaagagcac tgcggtgctt ggaactgcta
    13921 cacttgctag cttgcttttg gtagcttgcg gaagcaaaac tgctgataag cctgctgatt
    13981 ctggttcatc tgaagtcaaa gaactcactg tatatgtaga cgagggatat aagagctata
    14041 ttgaagaggt tgctaaagct tatgaaaaag aagctggagt aaaagtcact cttaaaactg
    14101 gtgatgctct aggaggtctt gataaacttt ctcttgacaa ccaatctggt aatgtccctg
    14161 atgttatgat ggctccatac gaccgtgtag gtagccttgg ttctgacgga caactttcag
    14221 aagtgaaatt gagcgatggt gctaaaacag acgacacaac taaatctctt gtaacagctg
    14281 ctaatggtaa agtttacggt gctcctgccg ttatcgagtc acttgttatg tactacaaca
    14341 aagacttggt gaaagatgct ccaaaaacat ttgctgactt ggaaaacctt gctaaagata
    14401 gcaaatacgc attcgctggt gaagatggta aaactactgc cttcctagct gactggacaa
    14461 acttctacta tacatatgga cttcttgccg gtaacggtgc ttacgtcttt ggccaaaacg
    14521 gtaaagacgc taaagacatc ggtcttgcaa acgacggttc tatcgcaggt atcaactacg
    14581 ctaaatcttg gtacgaaaaa tggcctaaag gtatgcaaga tacagaaggt gctggaaact
    14641 taatccaaac tcaattccaa gaaggtaaaa cagctgctat catcgacgga ccttggaaag
    14701 ctcaagcctt taaagatgct aaagtaaact acggagttgc aactatccca actcttccaa
    14761 atggaaaaga atatgctgca ttcggtggtg gtaaagcttg ggtcattcct caagccgtta
    14821 agaaccttga agcttctcaa aaatttgtag acttccttgt tgcaactgaa caacaaaaag
    14881 tattatatga taagactaac gaaatcccag ctaatactga ggctcgttca tacgctgaag
    14941 gtaaaaacga tgagttgaca acagctgtta tcaaacagtt caagaacact caaccactgc
    15001 caaacatctc tcaaatgtct gcagtttggg atccagcgaa aaatatgctc tttgatgctg
    15061 taagtggtca aaaagatgct aaaacagctg ctaacgatgc tgtaacattg atcaaagaaa
    15121 caatcaaaca aaaatttggt gaataaaaaa tttgttcaag gggggtggaa atcaaatccc
    15181 cctttgaatt tatcaataga gacacaaata atttagcttt cttataaaaa agtagtatcc
    15241 tatgaaagga gttaatatgg aaaagcaaca acctagtaaa gcagccctgc tgtctatcat
    15301 tcctgggtta ggacagattt acaataaaca aaaagccaaa ggttttatct tccttggtgt
    15361 aactatcgta tttgtccttt acttcctagc acttgcaacc cctgaattga gcaacctcat
    15421 cactcttggt gacaaaccag gtcgtgataa ttccctcttt atgctgattc gtggtgcctt
    15481 ccatctaatc tttgtaatcg tttatgtact cttttatttc tcaaatatca aagatgcaca
    15541 tacgattgca aaacgcatta acaatggaat tccagttcca cgcacactca aagacatgat
    15601 caaagggatt tatgaaaatg gcttccctta cctcttgatc attccatctt atgttgccat
    15661 gaccttcgcg attatcttcc cagttatcgt aaccttgatg atcgccttta ccaactacga
    15721 cttccaacac ttgccaccaa acaagttgtt ggactgggtt ggtttgacca actttacaaa
    15781 catttggagc ttgagtacct tccgttctgc ctttggttct gttctttctt ggactatcat
    15841 ttgggctttg gcagcttcta ctttacaaat cgtaattggt atcttcacag ctatcattgc
    15901 caaccaacca tttatcaaag gaaaacgtat ctttggtgtt attttccttc ttccttgggc
    15961 tgtcccagcc ttcatcacta tcttgacatt ctcaaatatg tttaacgata gtgtcggtgc
    16021 tatcaacact caagtattgc caatcttggc taaattcctt cctttccttg atggagctct
    16081 tattccttgg aaaacagacc caacttggac taagattgcc ttgattatga tgcaaggttg
    16141 gctcggattc ccatacatct acgttttgac tttgggtatc ttgcaatcta ttcctaacga
    16201 cctttacgaa gcagcttata ttgacggtgc caacgcttgg caaaaattcc gcaacatcac
    16261 tttcccaatg attttggctg ttgcggcacc tactttgatt agccaataca ccttcaactt
    16321 taacaacttc tctatcatgt acctcttcaa tggtggagga cctggtagtg tcggaggtgg
    16381 agctggttca accgatatct tgatctcatg gatctaccgt ttgacaacag gtacatctcc
    16441 tcaatactca atggcggcag ctgttacctt gattatctct atcattgtca tctcaatctc
    16501 tatgatcgca ttcaagaaac tacacgcatt tgatatggag gacgtctaag atgaataact
    16561 caattaaact caaacgtaga ctgactcaaa gccttactta cctttacctg attggtctat
    16621 caattgtaat tatctatcca ctgttgatta ccattatgtc agcctttaaa gcaggtaacg
    16681 tctcagcctt taaactagat actaatatcg acctcaattt tgataacttt aaaggcctct
    16741 tcactgaaac cttgtacggt acttggtacc tcaacacttt gattatcgcc ttaattacca
    16801 tggctgttca aacaagtatc atcgtacttg ctggttatgc ttacagccgt tacaacttct
    16861 tggctcgtaa acaaagtttg gtcttcttct tgatcatcca aatggtgcca actatggccg
    16921 ctttgacagc cttcttcgtt atggcgctta tgttgaacgc ccttaaccac aactggttcc
    16981 tcatcttcct ctacgttggt ggtggtatcc cgatgaatgc ttggctcatg aaaggctact
    17041 tcgatacagt gccaatgtct ttagacgaat ctgcaaaact agacggtgca ggacacttcc
    17101 gccgcttctg gcaaattgtt ctaccacttg ttcgcccaat ggttgccgta caagctctct
    17161 gggccttcat gggacctttc ggggactaca tcctctctag tttcttgctt cgtgagaaag
    17221 aatactttac tgttgccgta ggtctccaaa ccttcgttaa caatgcgaaa aacttgaaga
    17281 ttgcctactt ctcagcaggt gctatcctca tcgcccttcc aatctgtatt ctcttcttct
    17341 tcctacaaaa gaactttgtt tcaggactta caagtggtgg cgacaaggga taatttatcc
    17401 ccgccaccct ttttcatttt atactcttcg aaaatctctt caaaccacgt cagctttatc
    17461 tccaacctca aagttgtgct ttgagcaacc tgtggctagt ttgcactttg attttcattg
    17521 attattagca attgtcactg taaataatat ccttgtagca agcaattttt ctcctagact
    17581 tgaaataaag cgcatttctc tatataataa tacttatata gaaaacacct tttagaaaga
    17641 tacctatgct tccatatcca ttttcctttt tttcaagtat ttgggggttt cgtaagcccc
    17701 tgtccaaacg tttcgagctc aactggtttc aacttctctt taccagtatc ttccttatca
    17761 gcttgtctat ggtacccatt gctatccaaa acagctccca ggagacctat ccgctagaaa
    17821 cttttatcga taatgtctat gaacctctga cagataaggt tgtccaggat ctctctgaac
    17881 atgctacaat tgtcgatggc acattaactt atactggaac agttagtcaa gcctcttcta
    17941 ttgtgattgg tccaagtcaa atcaaggaat tacctaagga cttgcaactg catttcgata
    18001 caaatgagct agtcatcagc aaggaaagca aggaactgac ccgcatctct taccgagcca
    18061 ttcagactga gagtttcaaa agcaaagaca gcttgaccca agcaatttct aaagactggt
    18121 accaacaaaa tcgtgtctat atcagcctct tcctagttct cggtgcgagc ttcctctttg
    18181 gtttgaattt ctttatcgtc tctctaggag ctagtcttct cctttatatc actaagaaat
    18241 cacgcctctt ttcatttaga acctttaaag agtgctatca ctttatcttg aactgtttag
    18301 gattgccgac tctgattaca cttattttgg gattatttgg ccaaaatatg acaaccctga
    18361 ttactgtaca aaatattctt tttgttctgt atctggtcac tatcttttat aaaacacatt
    18421 tccgtgatcc aaattaccat aaataggaga tttttatgcc cgttacgatt aaagacgtgg
    18481 ccaaggctgc tggtgtttcg ccttcaaccg taacccgtgt tattcaaaat aaatcaacca
    18541 ttagcgacga aacaaaaaaa cgcgttcgca aagctatgaa ggaactcaac taccacccaa
    18601 acctcaacgc tcgtagcttg gtaagcagct atactcaggt tatcggatta gttcttcctg
    18661 atgactcaga cgccttctac cagaatcctt tctttccatc ggttctacgt ggcatctctc
    18721 aagtcgcatc tgaaaaccac tatgccattc agatagcaac agggaaagat gagaaggagc
    18781 gtctcaacgc tatttcacaa atggtctacg gcaagcgtgt agatgggcta atctttctct
    18841 atgcccaaga agaagaccct ctcgtaaaac tcgtcgcaga agaacagttc cccttcctta
    18901 tcttaggtaa atctctatct cctttcatcc cacttgtcga caacgacaat gttcaagctg
    18961 gttttgatgc gactgaatat ttcatcaaaa aaggctgcaa acgcattgcc tttatcggag
    19021 gaagtaaaaa gctcttcgtg accaaagacc gtttaacagg ctatgaacag gcgcttaaac
    19081 attacaaact taccactgac aacaatcgca tctactttgc cgacgagttt ctggaagaaa
    19141 agggctataa atttagcaag cgattattca agcacgatcc acaaattgat gctatcatca
    19201 caaccgatag cctcctagct gaaggtgttt gtaactatat tgccaaacac cagctggatg
    19261 tccctgttct cagctttgac tcggttaatc ccaagctcaa cttggcagcc tatgtcgata
    19321 tcaatagttt agagcttggt cgtgtttccc ttgaaactat tctccagatt attaatgata
    19381 ataaaaacaa taaacaaatt tgttaccgtc aattgatcgc ccacaaaatt atcgaaaaat
    19441 aagagactgg gcaaaaagtc gttaaaagca aaaacgcata ctatcaggta ttgaaaaaac
    19501 ttgatactat gcgttttatt gtgggaagat ttacttcctt ttctactgaa attgagtctt
    19561 ttcccaagat ctttttatac tcaatgaaaa tcaaagtgca aactaggaag ctagccgcag
    19621 gttgctcaaa acactgtttt gaggttgtag atgaaactga cgaagtcagc tcaaaacatg
    19681 gttttgaggt tgcagataga actgacgaag tcagtaacat atatacggca aggtgaagct
    19741 gacgaggttt gaagagattt tcgaagagta ttaatcacta attatctatc tcaacaaatc
    19801 ttcctagaat atgaacattt tccgagacag agacaaagga gcttggatcc acttgtgtca
    19861 taatctgttt aaattcatta aactctgcac gtgtaatgac agtgattaaa actgcctttc
    19921 tctcgtgatt ataggttcct tctgcatcgt ggatcatggt tgctccgcgg tgcaattttt
    19981 tatggatttt ttcaattacc ttctctggat gatttgtcac aatcatggcc tgcatacgct
    20041 tttgcttagt aaagactgcg tctgtcacac gactagagac aaagatggta atcatagaat
    20101 aaagagcgta tttccaacca aaggtcaaac ctgctatcag catgatagtt ccatttacca
    20161 agaaagaaat actaccgaca ttcttacccg ttttcttgcg aatagtcagg ctgacgatat
    20221 ccgtcccacc actggagata ttgtttcgaa gagcaaaacc aatccccaaa cccataacaa
    20281 cacccccaaa aagggcattg ataatgggat cctccgtcaa ggttgccaca gggacaaact
    20341 ggataaagaa ggaactcata gataccgtga taaaggtaaa gacggtgaac ttatggccaa
    20401 tctgatacca agctaagacc atcaaaggga agttaatggc gtagaagctt agcgaaatcg
    20461 gaatatgaaa accaaaccag tgattactca aggcagagat aatctgtgcc agacctgttg
    20521 caccactcga atacacatgc cctggttgga aaaagaaatt aactgctact gctgataaaa
    20581 aaccatagac cagagaggcc gaaatcttct catcatactt ttctcgagag atactttgta
    20641 agacacgtaa aatttttatc tgataagcaa agcggcgcag ataatagcgc caccgcttaa
    20701 ttcgttttgc ttgtttcatc ttcttctact tgtaagctga gttcctctag ttgtttgaga
    20761 gcgactgttg atggagcttg tgtcattggg tcagttgcct tgttgttctt aggaaaggca
    20821 atgacttcac ggatattttc ttctccagca agcaacatga caaaacggtc aagcccgata
    20881 gccaaaccac cgtgtggtgg gaaaccatag tccatggctt caagaaggaa accaaactgg
    20941 tcattggctt cttcagctga gaaaccaaga gccttgaaca tgcgttcttg aaggtctttt
    21001 tggttgatac gaaggctacc accaccaagc tcataaccgt tcaagacgat atcgtaagca
    21061 atggcacgaa ccttagccaa atcaccttct aattcgtgag cagtctcttc ctgtggaagt
    21121 gtgaatggat ggtgggcgct catgtagcgg ccttcttctt cagaccattc aaacatcggc
    21181 cagtcaacca cccaaaggaa gttgaactta tcattatcaa tcaagccaag ctctttagca
    21241 atacgtccac gaagggcacc cagtgttgca ttagccactt caagcgtatc cgccacaaag
    21301 agaaccaagt ccttatcttc aagagcaagc gctgttgtca attcttcttg gataccagtc
    21361 aagaacttgg caactggtcc gtttaattct ccatcaacca ccttgaccca agcaagacct
    21421 ttggcaccat actgtttggc tacttccgtc atcttgtcga tgtctttacg tgaatagttg
    21481 tccgcagctc ctttgaccac aatcgctttt acagcaggtg cttctgaaaa gactttaaag
    21541 tctacacctt tgaccacttc tgtcaagtcc tgaagcaaca tgtcaaaacg agtatctggc
    21601 ttgtcagaac cgtaaagagc catagcatca tcgtatttca tacgagggaa cggtagcgtt
    21661 acttcgatgc cttttgtttc cttcatcacg cgcgcgatca agccttctgt aatatcttgg
    21721 atttctttct cagtaaggaa ggacgtttcc aagtcgacct gagtaaattc aggctggcgg
    21781 tctccacgca agtcctcgtc acggaaacat ttaacgattt ggtagtaacg gtcaaaacca
    21841 gcattcatca agagctgttt cgtgatttgt ggactttgag gaagagcgta aaaatgcccc
    21901 ttattaacac gagacggcac taaataatca cgcgcccctt caggcgttga cttagaaagg
    21961 aatggtgtct ccacgtcgat aaactccaac tcatccaagt agttgcggat agagtgggtc
    22021 accttggcac gaagtttaag attttccaac atttctggac gacgaaggtc aaggtaacgg
    22081 taacgcaaac gtgtatcgtc atttgcctca atgccatcct taatctcaaa tggtgttgtc
    22141 ttagctgtgt taagcacaat aagagctgtc acgtttaact caaccgcacc agttggcaac
    22201 ttatcattgg cttgctcacg cgcagcgacc tgaccagtca cctcaataac aaattcgcta
    22261 cgaaggcttt cagctgttgc cataacctct gcagatactt tttcagggtt gataaccaac
    22321 tgcatgattc cttcacggtc acgaagatcg ataaagatca aaccaccaag gtcacgacga
    22381 cggccaaccc atcctttcaa ggttatttct tgtccgatgt gttcctcacg aacacgacca
    22441 gcatacatac tacgtttcat tatttctctc ctcttttatt ctgttactat tttaccataa
    22501 aagcgcaggc tcttcatgaa aatcatcaga aaagtttgcc agtctttaaa agtcaggtga
    22561 aagccctaaa aattagcgct aatactcttc gaaaatctct tcaaaccacg tcagcgtcgc
    22621 cttaccgtag tacggttact gacttcgtca gtttcatcta caacctcaaa accatgtttt
    22681 gagctgactt cgtcagtttc atctacaatc tcaaaaccat gttttgagct gacttcgtca
    22741 gtttcatcca caacctcaaa acagtgtttt gagcaacctg cggttagctt cctagtttgc
    22801 tctttgattt tcattgagta taatacaaaa atccgatgaa cttcaccgga ctcttttatt
    22861 ttgaattttt gcctgcttta cgcttttcag cgatttcggc tgcctttcga ggcaagacaa
    22921 tttccgttat gtaagccgtc ccaaaacgca gtacacctgc aataggagca aagacaactg
    22981 ctagatagtt atagaagaaa tcgcctttga aggcataagc tagcgctcca atgatgaaaa
    23041 atagaacgac tgcctgaatc actgctaata aaattactcg tttcatgtga cctcctgact
    23101 ctattatagc atgagaatca tcaaaaagcc gactaaatta ttcaaagcgt gaagagaaat
    23161 actgtagacc agaccttttc tgctaatgta agccaaaccc aaactaaaac caaggctaaa
    23221 atagacaaaa aattgttgca catcacctgg aaaatgaatc aaggcaaata gaagactaga
    23281 taccagaaga aaaatcaggg gtcgtttact attgtcctgc ttaggaaaga gatagcgtgc
    23341 taacatccct ctaaaaacaa tctcttccgt caaaggagca aaaataacca cagcaaagaa
    23401 tgagaaaagt ggttgagaca aggtcaagtc tgtcgctatt tgctgattta ctgaaggatc
    23461 atctggcaag aagaattgaa cgaccagaga taagaaccaa accaaggcag gaagccaaat
    23521 aaatcggtta aagccgctct tctcaatata aacaggagct ttctgatacc atttgtaaat
    23581 gccgtacaca tatactccag ccaagaccac atagagtaga gtaacagcat agggtgaagc
    23641 gcctaaagca agcgacgcag tcgcgagccc ctgaataaag ccatagataa agaaaaagga
    23701 tagaagggct agaagaaacc agccaaggtt tttaagtaat ttcatagata actcctttat
    23761 ttgaaataac gttttaccat aggtaactgc atcacattga tataaacatg gatggctcct
    23821 acaagcaaga aagctagtaa ctgaatctct cctgtcaaga aagaaaggat aataagaaaa
    23881 atatataagg ctggtaagac atattggtgt aattggaata aaattcgaaa actctgttcc
    23941 aaattagcct gacgctcccc ttcatcataa gaatttatat agttcaagac atcctttggt
    24001 gtagcgaaaa attccaaatc aaactgacga acaatcgcaa tggttttaaa aagagatttt
    24061 tgagcgacta agaataccac aaagagtaag aaagaaagga aaaatgtttg agggtttgta
    24121 tgcaatataa tcacctcact taatgaaata aaaatagcca atggaatcgc tacacctgta
    24181 atattaaaag caatggttcc aaactcaaga ttccgataca tttgcacata ataggtttca
    24241 ttcagatcgt catccatttc ctcttgatac aaggaatgaa attttctgct tttctttaag
    24301 aaattgaaag tcaaaaacat actaatgaaa cctatcagta aacaaatagc tgatatccat
    24361 ggcatcaagg cttttacatc taaaataatt tcgtgggatt cgacacgtgc cttaaacatc
    24421 cctacaaaca tgcccaagaa cccccccaag acaatagaca tcaaaaataa caatctacgt
    24481 ttctttttca tattcattct cctttttcac ttgctagatt tttggatttc ttttcaatcc
    24541 attcagttac tgggatgaga gcaaagtaga cccaaacaaa ttggtcgctt tgataaggat
    24601 taaaccagct taggtccatc ccaatcagta gaaatacgct gactaataaa gctatgacca
    24661 ctacataata aatcacttta tacttgttca tcactcgtcc tcctccaaac gaaataccga
    24721 ttcgactgtt tcgttgaaaa tttgagatat tttcagggca atgataatgg atggggtgta
    24781 ctcatcccgt tctagtaggc taatggtctg tctggaaacc cctgccagtt tggctaggtc
    24841 ggtttgattg agaccatcgc gagctcgaag ctcttttaga cgatttttta gttgcatgtt
    24901 acacacctac tctccgtcaa attcaacggt ttggatatct tcaatacgtt gcaacttgaa
    24961 tttttctttc ccctttttat caacactacg tagtttgacc cattcctcgt caacatccac
    25021 aacttcccag ttatctggcc caatatacac tcccgttata attggttcct ttccaatcat
    25081 ttcttgcaat aatctcgaca tttctgcgtt tcctttctct tttcgctcaa gttttttgat
    25141 tttattctct agtttcttga tttttttaga attattagaa taaaagaaaa tcataaatag
    25201 tataaatact agtacccaca ttataactcc tttctgcttc ctatttctta acttgaattc
    25261 attgtaacac atctttttct ttttgacaat tatagttgtc aaaaagttta tgatttttgt
    25321 cattttgcaa aagaaaaagg tcaggagtaa gttcctgacc actttatcta tcattaatac
    25381 tcttctaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtaggtatg gttactgact
    25441 tcgtcagttc tatctacaac ctcaaaacag tattttgagc tgacttcgtc agtttcatct
    25501 acaacctcaa aaccatgttt tgagctgact tcgtcagttc tatccacaac ctcaaaacag
    25561 tgttttgagc aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtataaa
    25621 atcctagttt ttcaaagatt tctgagaagt tttggctgat tgtctcaagt gacacttgca
    25681 cttcttctcg ggtttggttg ttcttgaccg tcacttgtcc gctttcgact tcgctctctc
    25741 ctagggtgat gagggtctta gccgcaaaga catctgctga cttgaactga gctttgagct
    25801 tacggttgag gtaatcacgc tctgctttga aaccttgttg gcgaagagct tggactagtt
    25861 ctagggcttt gacatttgct ccatcaccca agactgcgat atagacatct agggcgtttt
    25921 cgatagggag ggccacgcct tgtttttcaa ggatgagaag caggcgctct acaccaagcc
    25981 caaaaccaaa tccagcagtt tcagggcctc caaagtaagc aaccaaacca tcgtagcgac
    26041 cacccgcaca gactgtcaag tcattgccct caatctctgt gataaactcg aaaatggtgt
    26101 ggttgtagta gtccagacca cgcaccatat tggtatcgat gatgtaatct actccaagat
    26161 tttccaacat ctgacgcaca gcatcaaaat gagcttggct ttcttcatca agaaagtcca
    26221 agatagacgg cgcattctct actgctacct tgtcttcttt ttccttagag tccaagacac
    26281 gaagaggatt ttcctccaag cgacgttggc tatccttaga caaggtctcc ttgagcggtg
    26341 tcaaatagtc aatcaaggct tggcggtagg ctgcacggct ctcaggattt ccaagagtgt
    26401 tgaggtgcaa tttgacacct tgaataccga tttccttcaa aaaatgggct gccatagcga
    26461 ttgtttccac atcggtagct ggattgctag agccaaaaca ctcaacacca atctggtgga
    26521 attggcgcaa gcgccctgcc tgtggacgct cataacggaa cataggtccc atgtagtaga
    26581 acttgcttgg cttttgcact tctggggcga agagtttatt ttccacatag gaacggacaa
    26641 cgggcgcagt tccttctgga cgaagggtaa tatggcggtc acccttgtca tagaaatcgt
    26701 acatttcctt ggttacaata tctgttgtat ctccgacaga gcggctgata acctcgtaat
    26761 gctcgaaaat aggcgtacgc acttctgcgt agttgtagcg tttgaaaatt tcacgggcaa
    26821 agccctcaac gtactgccac ttggcagatt cagcaggtaa aatatcctgc gttccttttg
    26881 gtttttgtaa tttcataggg aatcctcttt aaacttaata gtcttatttt accataaata
    26941 gagggattaa aacagtgaga aaaaaattag gatttagata tcatttttga gattaagaat
    27001 tgttaaaaaa atagctagca aggaaagacc aacaaatagc atccaagtca actgcatgtt
    27061 ccatacggct actagtgaaa aacaagctgt tcccacaggt atggataagg taaacaatag
    27121 atctaaaaaa ttactagtac gagctagaac ctctggagct agatttttca tgagcatggc
    27181 actaatcttt ggttgaactt taccagacac atacagagta aagaagagaa atagcaaacc
    27241 aagcacgact tgattgaata aattagccaa accaactaga ctaagtccta cggtcgccca
    27301 catcatcaat ctaggcaagg actgcttccc aaaataatca ttgcccgtaa ggctactgat
    27361 gatgattgct actaaaacac agaattgatt gataaatagt gcctctgtat aagaaaaatt
    27421 caagagagaa tggctcaaaa agaagatatt ataaattcca cccaaagcgc cacccaagga
    27481 attaataagc aagacagcaa agagcataaa accaaagttt ttctgtccac ttttaagaaa
    27541 aacgagacgt aaatttcggt aaattgttag gaactggtct ttgatagaaa acttctcatt
    27601 ttttaagttt tcaccatcag cagatgacat tgacaggctc aatttgcttt ttcctaaaaa
    27661 gaggatagtg gctgatacta ggaaaaagca ggcattgatt cccgcaacga gagaaaaatt
    27721 gttgaccgat agagctaaga gccagactcc gaaagcttga ccaccaatag ctgaaatata
    27781 ggtgatgaac tgtgaaaaag aataagcctc catcagatca tcttcagcta ctttttcctt
    27841 aataagaggc atacgcaggc cacctgcaaa atcactgatg atatcactaa tgacattgat
    27901 caaacacagg ctagaaaagg caaagagact agcttgctga acaactaggg ctgctagaaa
    27961 aaatagaacc gcctgaaaca aaccgctata gaccatccat ttgaccttgt ccctcgtgta
    28021 atctgcccga atccctgcaa aaactgtaaa gaaggtcgga agaatcatga caatattcgc
    28081 catagcaaca gcaaaagatg cttgtgacaa ggtcgatgca tagacgataa agaccaggtt
    28141 gaaaatcgaa gcaccaaaag cattgaagaa gcgtgataaa gtcaaaattc tataagctgg
    28201 atttctaaac aatagtttca tagataatct ccctccttgt tctaagttct acatcaagaa
    28261 tagctttagt atagcactta tgaatttgcg aaacgattct tttgaatata tgcaacaaac
    28321 aaaatgagca aaaaaacgat agaacttttg taatgacctg agagagggca acagttctat
    28381 cgcttcaaat tttttcttgg tttgcagata ctcaacattc ggtcgtattt ctatagtatt
    28441 cggcagattt attacagcca agcatctcaa aaatacggac agcatcctcc atctttttct
    28501 gaccttcctt gactctacct tgcttgctat caaggagacc ttctgcccac agataaacaa
    28561 ttcggaaata ggtctcattt tccttgtaga aatgctcttc gataacacgt ttaaaataat
    28621 aggcattggt aaattcttca cactcaatac tagctaaaaa gccattcaat agtatagtat
    28681 gaaaaaggtt tcgattgcca gacatttcca ttagaaaatc agatttacgt accatttctc
    28741 gtacatatct agtaaaaaga gaaacagata aaaatggaga actgactgaa aataaattga
    28801 gttcatagat tccccagatc tcggtagaaa acaaataatc atgaaggact tttccttcct
    28861 ctgctgttaa ctctaccctt tcatctatgc tcttcatata agacttgata ataatggcat
    28921 ttagaatatg tttctgtttg ttgtgagaat gggcatgctt ttgatactcc ctgcgatata
    28981 agtcctcaag aggtgctata ttctttggtt ccaagacatc tgtaatttct tttctcaact
    29041 cagaatctgt atcatactgg aaacctctcg ccagaaagag gatctcctcc acactggcag
    29101 atatattttc cagagcaaat agaaactttt ccaccgaaag ctcactctga cctgtttcaa
    29161 aacgggacaa catagacggc gaaaattgtc ctccggttgc ttgtctcagt gagatatttc
    29221 ttgactctcg taattgtcta aagacttttc caatctgctc catagacttc cccttgattc
    29281 cgtattttct tcattttatc atatttttca gaaaattcat caaaaacttg ccaaattgtc
    29341 agaattatga gaaaatagag gatatttatc acgtggaggg actgctatga gagacgatat
    29401 caaaatcaat gaccgtgctt tggccttgca agaccaaatc atcgaaaaac tagagaaagt
    29461 ttttgataca gatgtggaat tggatgttta caatctaggt ctgatttatg aaatcaatct
    29521 ggatgaaacg gggctctgca agattgtcat gaccttcacc gatactgcct gtgattgcgc
    29581 cgaaagcctg cctattgaaa tcgtggcagg tctgaaacaa atcgagggta tcaaagatat
    29641 caaggttgaa gttacctggt cgcctgcttg gaaaatcaca cgaatcagtc gctatggccg
    29701 tattgccctt ggactaccac ctcgttaagc aggccaatca tttttaaaga tgaaaaaagc
    29761 aagccaaaaa tggcttgctt tttgatactc aatgaaaatc aaagggcaaa ctagaaaact
    29821 agccgcaggt tgctcaaaac actgttttga agttatggat agaactgacg aagtcagccc
    29881 aaaacactgt tttgaggttg tggatagaac tgacgaagtc agtaaccata cctacggcaa
    29941 ggcgacgttg acgtgatttg aagagatttt caagtatgag tttatttttt acctgacttg
    30001 tccatattcc agaagtctgt cacggctccg cgtgaagcag atgatacgat atgggcatat
    30061 ttaccgagga caccacggct gtaaagtggt ggcaaggttg tttctgcctt gcgtttttca
    30121 agttcttctt cggatacggc catggaaatt tctttggtat cttggtcaac cgtaacgata
    30181 tcgccggtac ggagataggc aattggtcca ccatcctgag cttcaggagc gatatgtcca
    30241 acaaccagac cataagtacc accagagaaa cgtccgtccg tcaagagggc caccttatct
    30301 ccctgacctt taccaacaat cattgaagaa agtgacagca tctcaggcat accaggacca
    30361 cctttaggtc caacaaaacg aacaacgact acatcgccat caatgatttc atctgtcagg
    30421 acggcctgaa tcgcatcttc ttctgagtca aagaccttag ctggcccaac gtgacgacgc
    30481 actttaacac ctgatacctt ggcaactgca ccgtcaggag caaggttccc gttcaagatg
    30541 ataagcggac catccgcacg ttttggattt tcaagtggca tgataacttt ttggcctgga
    30601 gtcaagtctg caaagtcagc caagttttca gctacagtct taccagtaca tgtgatgcga
    30661 tctccgtgaa ggaaaccatt tgccaacaag tacttcataa ccgcagggac accaccgact
    30721 tcgtagaggt cttggaagac atactgacca gatggtttca agtcggccaa gtgaggcaca
    30781 cgttcttgaa tcgtattgaa gtcctcaagt gacaagtcaa catttgcggc atgggcaatg
    30841 gcgagcaagt gaagagtggc gtttgtagaa ccaccgagag ccatcgttac agtaatagca
    30901 tcttcaaagg cttcacgagt caagatatct gatggtttga gaccaagttc caacatctta
    30961 acaacagcac gtcctgctgc ttcgatatct tctttcttat cagctgattc agctgggtga
    31021 gaggatgacc ctggcaaact catccctaga acttcgatag cagttgccat ggtattagca
    31081 gtatacatac caccacaacc accagggcca gggcaggcat tacattcaag acgtttcacg
    31141 tcctcagctg tcatgtcacc gtggttccat tttccgatac cttcaaagac agaaaccaag
    31201 tcgatatctt taccatcaag atttcccggt gcaatagttc caccataggc gaaaatagct
    31261 gggatatcca tattagcaat agcaatcata gatccaggca tgttcttgtc acagccaccg
    31321 atagcgacga aggcatccac gttgtgacca ctcatagccg cctcgatgga gtccgcgatg
    31381 atgtcacgag atgttagaga gaaacgcata ccaggcgttc ccatagcgat cccgtccgct
    31441 acggtaatgg ttccaaactg tacaggccaa gcgcctgcag atttgacacc ttctttagcc
    31501 agtttcccga aatcatgcaa gtgaatgtta catggtgtat tttccgccca agtcgaaatc
    31561 actcccacaa tcgatgtttc aaagtcctta tctgtcatac cagtcgcacg aagcatagca
    31621 cggttaggtg atttaaccat gctgtcatag atgctactgc ggtgacgttt atctaattca
    31681 gtcatcttat ccctcccatt tcagttttta ctattatagc acaatttaaa ggcaatgaac
    31741 agaataaaat tcttgaattt tcagaaaatt ctatacgaat gtgaaatatt taaaattaaa
    31801 aacaacaaag cggattagtg cactttctga tgaccagaat atgcttttta atccgctttc
    31861 tttaaataac gtaatgtaat ttttacagaa attctttcag ataagtgtat ttaacatcta
    31921 tcttgcatta taaatttcta gaaccttctc ttttatattc gattcactca aaccatactc
    31981 attaagaaga taatccattt tccctacttg accaaatctt tcttgaacac ccatccgatg
    32041 aatttttgtt attccatcat cagagaataa ttcacataaa gcactgccaa ttccacctat
    32101 ctgattgtgg ttttctacag taaatatagt ttttccactt aacattgttt ttatctgttc
    32161 tggtatcggt ttgattctaa ataaatctat cacacctact gaataaccta atttagacag
    32221 ttcatctgca actcgaatac ttggagcaac cattatacca gaagcaacga ttacaagatc
    32281 ttcaccatgc cttaactcaa tgtagccttt agaaaaatct tctccacctt gatatacagc
    32341 ctctggagct tttctaattg ttcgaatata ttttagtcct tttaagtcta atgtctggtt
    32401 caatatttca cgaaattgga tatcatcagt tgcttcaaaa atgatcgatt taggaattaa
    32461 acgtaacaat ccaatttctt caaatggcat atgtgtccca ccattcattt ctgcagttac
    32521 tcctgcatct gatccaatca cagtggcatc caattgtgcg tatccaagag aaataaataa
    32581 ttgatcaaat acccttcgtg aagaaaaagg accaaatgta tgaagataag gtctaaaccc
    32641 ctgaatagac aagcctgctg caaggccgac catttctgct tccataatcc caacattcac
    32701 ataacggtct ccaaagtcct tttcaagatt atgagtagcc atcgaacttg acaaatcggc
    32761 ttctaagact actatatcag aataactttg attagcctct aaaaggaagt ctctatatac
    32821 ataccgtaat tctttcgtac ttctcatcat tctgtttcct ccaattcctg acttaatctt
    32881 tctacaactg aagttaacat ttgtctctcc tctacagtag ggcgaagatg atgattggat
    32941 ttcatttctt ccagctcttg aaccccttga cctttaatag tatctaatac aatgcactta
    33001 ggtgatgaat tatttgactg ttttaattgg acaatccctt cataaatttc tctaatatct
    33061 gaacccttga ccctaatgga ttcaaatcca aatgctgaaa atttttctac gaaatcacct
    33121 ggattacaaa tatcctttgt aaaaccatct aattgttttt tgttatcatc aacaaataca
    33181 attaagttgg ataactgttg atgagaagca aactgtatag cctcccaaca ttgtccctca
    33241 tttaactcac catctccaac aatagcataa gtataaaagg gactctttct tattctctga
    33301 ccatatgcaa gtccagttgc aacactaatt ccttgtccta aagagcccgt tgtcatatct
    33361 atgcctggcg ttagatttct atcaggatga gacggtaatt tggttccatt tgtatttaaa
    33421 gaatataaga attctttgtc aaagaaacca ttcaaataga gtgtactgta tagagctggt
    33481 cctccatgac cttttgataa tatgaaataa tctctatctc gtgctgcaaa tatttctgga
    33541 gtcattggca ttatttcacc ataaagcact gctaaaactt ctacgataga cagacttcct
    33601 ccgtaatgtc cgaatccaag atgattcaat gttctaagag tatttaatcg gatgttggtc
    33661 gcaaattttc ttaactcatc ttctctattt ttacttaaaa tcatccctta ttcctccttt
    33721 gcagatggct ttttaataaa ggatactcca aacataactg ctaaaataag aacaagacca
    33781 atcacaatgc ctgcttgtga gccaaattga tttaacattc ctaaaataat tcctgataga
    33841 ccaaaatctg catctgagaa agttgatcct tggaaaccga gtcctcccaa aactggcatt
    33901 aaaaagactg ggagaaaact gattaaaata ccttgtaaaa atgctccaat agtggctcca
    33961 cgaacaccac cagatgcatt cccaataaca cctgcagtcg ctccacagaa gaaatgaggc
    34021 acaacgcctg gtaagataac aaccgttcct gaagcaatca taattaccat acttactaaa
    34081 ccaccaataa aactagagat aaatccaatt agaactgcat taggtgcata agtataaaca
    34141 atcggacaat ccaaagcagg ttttgaatta ggtacaagac gctctgaaat acctttaaag
    34201 gctggaacaa tttcgcccaa aataaggcga acacctgcta aaataacaaa tacccctgct
    34261 gcaaattgac ctgctaattg taaagcataa actagaccac ttgtaccact actgatttct
    34321 ttttctatat attctgaccc tgcaaagata gctacaataa tgtaaataac tgccatagat
    34381 aaagtgatac taacagtact atcacgtaaa aaagctaaac tctttggaaa tttaatgtcc
    34441 tctgttgatt ttgatttgtc accgataagg ctaccagtaa aaccactcaa ccaatatccc
    34501 aaagaactga aatgacctaa agccaccttg tcatttccag ttaattgaac catatatttt
    34561 tgcacaaatg ctggggaaat actcataata ataccgagtg ctaatcctcc tagtaagatg
    34621 agaggcaagc tagtaaagcc agcaactgat aaaatgaccg caatcataca tgccatatat
    34681 agagtgtggt gccctgttaa aaaaatatat ttaaatcgag taaaacgagc gattaagata
    34741 ttgaacacca ttcctgcaaa cataatcatt gcagtagctg agccatatgt tgttaaagct
    34801 acagctacaa ttgcttcatt attcggcaca acgccagata aatgaaaagc atgctcaaac
    34861 atggtaccaa atggatttaa agaattttgt acaattcctg caccaccaga tacaactaag
    34921 aaaccaacaa aggtcttaat tccaccttta ataatatcag gtaatttctt cttctgaaga
    34981 actaatccta aaattgcaat taaagctact aaaatagctg gtgtactaac aatatccaat
    35041 atgaacttca tcatgacgct agcctcctat ataagtcctt tttcttcaca aagtttagta
    35101 attaattctc gtagttcatc catatcaata atactattta agatacgaac atctccaaga
    35161 tgactagctg aatcagctag atcacgacca acaatccaaa tatcagctgc atttggatct
    35221 gctccaccta aatcataatg ttcaacttct acatccgaaa cattcaaatc actcaataca
    35281 gattcaatat tcatctgtac cataaaactt gaacctaatc ctgaaccaca agctgtacca
    35341 atttttaaca ttatctaatc ctcctgttta attatcattt taatatcatt atagtttttt
    35401 gatgatatta aagtttgaac atgattttta tctcttaaaa ttgttgttaa atgtgacaaa
    35461 gcctttaaat gactctcatt atcaatggct gcaatacaaa tcaacaatct tacctcttgt
    35521 tctggattat ccaataaata aatcggttct tccaaaacta acattgacat tcctatttca
    35581 ttcacacctt catctggccg agcgtgagga attgctactc ccttccctaa attaataaaa
    35641 ggtccaaact cttctacttt ttgaatcatt gcctcagggt agttctcagt tatcttatct
    35701 tgatccaaaa gcggtttagc tgctaaacga atcgcctcct tccatcctaa tttttgcgaa
    35761 ctaacctgat aggtttcttt ggtaatgagt tgttctagca ctggtacaat ttcctttcta
    35821 tcattttttt ggtaaagata attctttaac gccaatctta attccaattc ttgtgtaata
    35881 attccatatc ttttgacaat attcaggatt tgttcaatct caaaatcccc atactctaaa
    35941 ttcggaaaat cttttaacac tagttctact agttgtattg cttgctcttc agtcatcata
    36001 accgaaacta gataatttgg cttttctgtc tccaccttta tggtagaaaa aaccatatca
    36061 tagtcactac tagctttcac ctgtaaatca tcaatctttg aggttcctat aaactcaatt
    36121 tgaggaaata atgctaatag attctctttt aacatcaatg aagaactaac accattagga
    36181 caaatgattg ctgctttata gcatttttga ggcaaagtat ctgctttctt taaataacct
    36241 ccgaaatgga taacaaaata tgctgtttca ctatcaggta tgggattgtc aatagcgtcc
    36301 atcaagggca tcaaagaatc tttgactaat tcaaataaat caggataatg ttctttaaca
    36361 tgcaatacat attcatttga actaggtagg ccgaacttta atctatagta agccggtata
    36421 aggtggcggc gaagattttc tctcaatcct tccctttgtt taaaatgtaa caaagaaata
    36481 tcttccattc tacttataat agcctctgtt aattgattaa agtaaaccgg agcaacatct
    36541 acttcacctt caaagcaact tgataataaa acggtgatat agcgataatc atcctcagaa
    36601 aacaccgtat ctataattcc caaatcaacc actgtatcca ataaaatagt cgttatatct
    36661 tgaataacag gagatactaa tgtctctgaa agacatactc tttcaacatc cctttgatac
    36721 ctacacagaa tgaatactaa accgaaaagg taaactttta attgattaac aataggtact
    36781 agctgtagct tctcataata atctttaact acctgatcaa tcaaatcata agttaatgaa
    36841 tacccccaac tggataaaac ataatccaaa ccccaaatcc ctatggagga ttccagcaac
    36901 tcactaacca tttgaaaagc taaacggtgc ttattccact ctgaaccgtg taaagtataa
    36961 ccttttgctc tactgtaccc tagctccaaa tcattatcta acataatctt tcttaatgat
    37021 tgaatatcag ataaggttgt attcttactt actttcaaaa agtcttggta atgattattc
    37081 gatataaaat ctaatcggca aaaagtgtaa agatagatta aagctaagcg agtcgacttt
    37141 ggtaaaacca attcatccga cttaataata tctgtcaaag actgcttcgt acgatttgat
    37201 aaactatagc gaccttgctt tttatccagc actatccctt tattagctaa ataaggcact
    37261 aaataatcta ttccttcttt gacttccttt ataggtaagc tcaccttaac agataactca
    37321 tataatgata cctcacaatg atccatcaaa gtcatcaaaa taactagtgc tctataatca
    37381 aacatttctc ttcctttcta actacaatta tagtgtaaaa gttataagaa taaaagagta
    37441 tttgagcaca atataatctc accttttaaa agaaattatt gggctgaaag tttttagtga
    37501 ttatttttca actttctatt gacttttaaa aacaaagtga tatcatttag atatcaaata
    37561 atgggaggtc attcttatga ctgaaaaact aatcaattca aaaccaaatg gtgtattcgc
    37621 attgattctc attgaattga cgctcgtact tggtatcttt atatttataa tgggtgttgg
    37681 ttcggaaaac atttttggaa ttattatcgg acctttacta atcgtaattg caggtctagc
    37741 tcatgctggt ttaaaagttg tcaaacctca ggaagctctg gttctgacac tctttggtaa
    37801 ttatacaggt accatcaaag aacctggttt ttactttgtc aatcccttca gcgtagcagt
    37861 caaccctgca aaccacactc gacttggaca aagtggtgat gttagcacaa aatctccttt
    37921 tttaggtgct aaatcatcaa atgacaatga tgtaaatctg gaaattggca agaaacacat
    37981 ttccctcaaa gtcatgacct tgagcaattc tcgtcaaaaa atcaatgatt gcttaggaaa
    38041 ccctgtagaa atcggtatcg cggtaacttg gagagttgtc gataccgcta aggcagtctt
    38101 caacgttgat aactacaaag aatatctttc attgcaatgt gatagcgccc tccgtaatat
    38161 tgtccgcatc tatccttacg atgtgtctcc taatgtggat actacgggtg acgggcaagc
    38221 agatgaaggt agtctccgtg gctctagcga aattgttgct aaccgtattc gtgaagaaat
    38281 ccaaagtcgt gttgaggatg ctggcttgga aatccttgaa gcacgtatca cttacctagc
    38341 ttatgctcca gaaattgctg ccgttatgct tcaacgccaa caagcatctg ccattattga
    38401 tgcacggaag atgattgtag atggtgctgt aggaatggtt gaaatggcac tagaacggct
    38461 caatgaaggg gaattggtag aacttgacga agaacgaaaa gctgccatgg tttcaaatct
    38521 ccttgtcgtt ctttgtggca atcatgatgc acaaccaatt gtcaacacag gaagtcttta
    38581 ctaaagatgg ctgaagctaa aaaaaagcag atcccccttc gactctcaac aaagttatac
    38641 gctgcactcg catcatgggc agaagacgac tttcgttcag tcaatgggca aatcgaatat
    38701 ctcctcacag agtgtgtcaa gcaacggaag aaagacggaa aatacgtatc agaaaccatt
    38761 gacgaaccat ttgagattga tatttaacac cttctcctgt ctgccgtgtc ggataggaga
    38821 attttttcat ctttttttgt caagtaactt tactttacaa aaaaaatgtg ttatcctagt
    38881 atggttgatg aagatcagta gattgaatcg aatataaata cctaaaggag aaatcaaaat
    38941 ggcagtacct gcacgtcgca cttcaaaagc gaagaaaaac aaacgtcgta cacactacaa
    39001 agtaacagct ccatctgtaa actttgacga aactactgga gattactcac gttctcaccg
    39061 tgtatcactt aaaggatact acaaaggacg taaaatcact aaagctgcat cagctgaata
    39121 atagaaggga gataccatgc gcgtaaatat tacacttgaa cacaaagaat ctggtgaacg
    39181 cttgtacctt acttctaaaa acaaacgtaa cactccagac cgccttcaat tgaagaaata
    39241 ctcaccaaaa cttcgcaaac acgttgtgtt tacagaagtt aagtaagcat tcaatacgaa
    39301 tcaatacaga agaaaaacgc ttgatcagcg ttttttcttt ttgttaattt cactatattg
    39361 caagggaaat cattcgaatg actacctttt tcactacctt ttttgaaata agaatacgga
    39421 ttcggacaat taaaagcaag aggaactcaa atgtaagttg gggttccttt tttgtatatt
    39481 tttcaaataa cgcctctaca ctatttgtag caaattcacc aactacagtt gtatcttagt
    39541 taaaataagt tagaatatgt aagtgagtac cagatatacc aagacatcgt caccatctaa
    39601 ggtatattca aaatacaaaa gttgaccaac tagatttctg aatatcctta tatatccatt
    39661 cttaaaattg gtttaaatag cgtagtcttt taaactagtt ttgagaatcc aaaaaatctt
    39721 cctacatatg taagaagatt ttttagttca gaatgattag atttagctaa tggataccta
    39781 tcctacccac tcaccgttag cattgactcg atagccatcg ggtgtagtcg tgtttactaa
    39841 taaatctcct gaattatagg tatagtacca tttaccagaa actgtaaacc aaccagtagc
    39901 cattgaacct gattc
//
LOCUS       DBERXF010000017        39321 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.17, whole genome shotgun sequence.
ACCESSION   DBERXF010000017 DBERXF010000000
VERSION     DBERXF010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 39321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39321
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.17"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            307..2460
                     /gene="comA"
                     /locus_tag="ACL8JK_000998"
     CDS             307..2460
                     /gene="comA"
                     /locus_tag="ACL8JK_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="HGS1785898.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2473..3822
                     /gene="comB"
                     /locus_tag="ACL8JK_000999"
     CDS             2473..3822
                     /gene="comB"
                     /locus_tag="ACL8JK_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence pheromone export protein ComB"
                     /protein_id="HGS1785899.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGTSLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            3992..4699
                     /gene="purC"
                     /locus_tag="ACL8JK_001000"
     CDS             3992..4699
                     /gene="purC"
                     /locus_tag="ACL8JK_001000"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGS1785900.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            4756..8481
                     /locus_tag="ACL8JK_001001"
     CDS             4756..8481
                     /locus_tag="ACL8JK_001001"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HGS1785901.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITIGIAKQEFS
                     ESDKTIPKLPFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTATHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDINGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAVGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANNTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            8574..10016
                     /gene="purF"
                     /locus_tag="ACL8JK_001002"
     CDS             8574..10016
                     /gene="purF"
                     /locus_tag="ACL8JK_001002"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGS1785902.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGTGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAVCSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSMTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10053..11075
                     /gene="purM"
                     /locus_tag="ACL8JK_001003"
     CDS             10053..11075
                     /gene="purM"
                     /locus_tag="ACL8JK_001003"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGS1785903.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLVSSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11072..11617
                     /gene="purN"
                     /locus_tag="ACL8JK_001004"
     CDS             11072..11617
                     /gene="purN"
                     /locus_tag="ACL8JK_001004"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGS1785904.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            11701..12210
                     /locus_tag="ACL8JK_001005"
     CDS             11701..12210
                     /locus_tag="ACL8JK_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGS1785905.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12235..13782
                     /gene="purH"
                     /locus_tag="ACL8JK_001006"
     CDS             12235..13782
                     /gene="purH"
                     /locus_tag="ACL8JK_001006"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGS1785906.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAANENQIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYTVVLDELSAN
                     GETTYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIAVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYDLTMVFT
                     GVRHFRH"
     gene            13904..15166
                     /gene="purD"
                     /locus_tag="ACL8JK_001007"
     CDS             13904..15166
                     /gene="purD"
                     /locus_tag="ACL8JK_001007"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGS1785907.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTATYGTFSDFEEAKAYIENHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPMAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIKGLFYRTDIGSKAIK"
     gene            15423..15539
                     /locus_tag="ACL8JK_001008"
     CDS             15423..15539
                     /locus_tag="ACL8JK_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGS1785908.1"
                     /translation="MKERLDDNPIVQGNWKTLGFQFRHETPLVAAAVPHKLR"
     gene            15569..16057
                     /gene="purE"
                     /locus_tag="ACL8JK_001009"
     CDS             15569..16057
                     /gene="purE"
                     /locus_tag="ACL8JK_001009"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGS1785909.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVISAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDRSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16044..17135
                     /gene="purK"
                     /locus_tag="ACL8JK_001010"
     CDS             16044..17135
                     /gene="purK"
                     /locus_tag="ACL8JK_001010"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGS1785910.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            17145..17372
                     /locus_tag="ACL8JK_001011"
     CDS             17145..17372
                     /locus_tag="ACL8JK_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGS1785911.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            17435..18733
                     /gene="purB"
                     /locus_tag="ACL8JK_001012"
     CDS             17435..18733
                     /gene="purB"
                     /locus_tag="ACL8JK_001012"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGS1785912.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(18788..22672)
                     /gene="strH"
                     /locus_tag="ACL8JK_001013"
     CDS             complement(18788..22672)
                     /gene="strH"
                     /locus_tag="ACL8JK_001013"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored beta-N-acetylhexosaminidase StrH"
                     /protein_id="HGS1785913.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKDKPAKKDEAKAEADKPATEAGKERAA
                     TVSEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDLHLLVGNDGLRFMLDDMS
                     ITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDLINYAKDKGIGLIPTVNS
                     PGHMDAILNAMKELGIQNPNFSYFGKESARTVDLDNEQAVAFTKALIDKYAAYFAKKT
                     EIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEKFIAYANDLARIVKSHGL
                     KPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASSKLLAEKGHQILNTNDAW
                     YYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPIIGGMVAAWADTPSARYS
                     PSHLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYTAESVAAVKEAEKAIRSL
                     DSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKREVEKLAKNKVISIDAGRK
                     YFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTITANGKTYASDDVKKAIIE
                     GTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPGHMDAMLVAMEKLGIKNP
                     QAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIFNFGTDEYANDATSAQGW
                     YYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYEDKDDVQFDKDVLISYWSK
                     GWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGFLKKAIENTGKTPFNQLA
                     STKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFADHNKDYFRANYNALREEL
                     AKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLVANLKAALQGLKPAATHS
                     GSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQENIITAGVKGERTHYIS
                     VLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGLAPTTEVKPRLDIQKEEI
                     PFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGKEVKTLVNSVVAQEAVTQ
                     IVEVGTMVTHVGDENGQAAIAEEKPKLEIPRQPAPSTAPAEESKALPQDPAPVVTEKK
                     LPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(22987..23703)
                     /locus_tag="ACL8JK_001014"
     CDS             complement(22987..23703)
                     /locus_tag="ACL8JK_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS1785914.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            24051..25838
                     /locus_tag="ACL8JK_001015"
     CDS             24051..25838
                     /locus_tag="ACL8JK_001015"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HGS1785915.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKWLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            25835..26311
                     /locus_tag="ACL8JK_001016"
     CDS             25835..26311
                     /locus_tag="ACL8JK_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1785916.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            26339..27244
                     /locus_tag="ACL8JK_001017"
     CDS             26339..27244
                     /locus_tag="ACL8JK_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS1785917.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            27231..28046
                     /locus_tag="ACL8JK_001018"
     CDS             27231..28046
                     /locus_tag="ACL8JK_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS1785918.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28053..28457
                     /locus_tag="ACL8JK_001019"
     CDS             28053..28457
                     /locus_tag="ACL8JK_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1785919.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            28756..29922
                     /locus_tag="ACL8JK_001020"
     CDS             28756..29922
                     /locus_tag="ACL8JK_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGS1785920.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKV
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTAYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            30038..31075
                     /locus_tag="ACL8JK_001021"
     CDS             30038..31075
                     /locus_tag="ACL8JK_001021"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGS1785921.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     IYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            31283..32137
                     /locus_tag="ACL8JK_001022"
     CDS             31283..32137
                     /locus_tag="ACL8JK_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS1785922.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWNIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            32287..32544
                     /locus_tag="ACL8JK_001023"
     CDS             32287..32544
                     /locus_tag="ACL8JK_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
                     /protein_id="HGS1785923.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDCDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(32586..32948)
                     /locus_tag="ACL8JK_001024"
     CDS             complement(32586..32948)
                     /locus_tag="ACL8JK_001024"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785924.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDGTDEVSSKHCFEVVDRTDEVS
                     NHIYGKVKLTWFEEIFEEYKSLHNKTHITKVLMNCTPKVRQKKSNFLGSVHSTPDTMR
                     FFNFKDFLQLLLTHIKLF"
     gene            complement(33002..33298)
                     /locus_tag="ACL8JK_001025"
     CDS             complement(33002..33298)
                     /locus_tag="ACL8JK_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGS1785925.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
     gene            complement(33288..33470)
                     /locus_tag="ACL8JK_001026"
                     /pseudo
     CDS             complement(33288..33470)
                     /locus_tag="ACL8JK_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691454.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
     gene            33519..34283
                     /locus_tag="ACL8JK_001027"
     CDS             33519..34283
                     /locus_tag="ACL8JK_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HGS1785926.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(34523..34675)
                     /locus_tag="ACL8JK_001028"
     CDS             complement(34523..34675)
                     /locus_tag="ACL8JK_001028"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785927.1"
                     /translation="MRTKASLRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTAR"
     gene            34893..36272
                     /locus_tag="ACL8JK_001029"
     CDS             34893..36272
                     /locus_tag="ACL8JK_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGS1785928.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            36286..36951
                     /locus_tag="ACL8JK_001030"
     CDS             36286..36951
                     /locus_tag="ACL8JK_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGS1785929.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            37261..37800
                     /locus_tag="ACL8JK_001031"
     CDS             37261..37800
                     /locus_tag="ACL8JK_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1785930.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            37867..38277
                     /locus_tag="ACL8JK_001032"
     CDS             37867..38277
                     /locus_tag="ACL8JK_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HGS1785931.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            38393..>39321
                     /gene="pavB"
                     /locus_tag="ACL8JK_001033"
     CDS             38393..>39321
                     /gene="pavB"
                     /locus_tag="ACL8JK_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HGS1785932.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKLEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNV"
BASE COUNT        10799 a         7665 c         9220 g        11637 t
ORIGIN      
        1 attttctagg tagaacgttt gttctgccta tttttttatc caaaaagtgc agttgggagg
       61 gagataggct catttgggaa ggaagtccag tttttgttta gtgattgggg taagatagtt
      121 gttatcagat gagtttatac tcttcgaaaa tcaaattcaa accacgtcaa cgtcgccttg
      181 ccgtatatat gtgactgact tcgtcagtcc tatctacaac ctcaaaacag tgttttgagc
      241 agcctgcggc tagtttccta gtttgctctt tgattttcat tgagtattag ggaaaaggag
      301 atgaatatga aatttgggaa acgtcactat cgtccgcaag tggatcagat ggactgcggt
      361 gtagcttcat tagccatggt ttttggctac tatggtagtt attatttttt ggctcacttg
      421 cgagaattgg ctaagacgac catggatggg acgacggctt tgggcttggt caaggtggca
      481 gaggagattg gttttgagac gcgagccatt aaggcggata tgacgctttt tgacttgccg
      541 gatttgactt ttccttttgt tgcccatgtg cttaaggaag ggaaattgct ccactactat
      601 gtggtgactg ggcaggataa ggatagcatt catattgccg atccagatcc cggggtgaag
      661 ttgactaaac tgccacgtga gcgttttgag gaagaatgga caggagtgac tctttttatg
      721 gcacctagtc cagactataa gcctcataag gaacaaaaaa atggtctgct ctcttttatc
      781 cctatattag tgaagcagcg tggcttgatt gccaatatcg ttttggcaac actcttggta
      841 accgtgatta acattgtggg ttcttattat ctgcagtcta tcattgatac ctatgtgcca
      901 gatcagatgc gttcgacact agggattatt tctattgggc tagtcatcgt ctacatcctc
      961 cagcaaatct tgtcttacgc tcaggagtat ctcttgcttg ttttggggca acgcttgtcg
     1021 attgacgtga ttttgtccta tatcaagcat gtttttcacc tccctatgtc cttctttgcg
     1081 acacgcagga caggggagat cgtgtctcgt tttacagatg ctaacagtat catcgatgcg
     1141 ctggcttcga ccatcctttc gattttccta gatgtgtcaa cggttgtcat tatttccctt
     1201 gttctatttt cacaaaatac caatctcttt ttcatgactt tattggcgct tcctatctac
     1261 acagtgatta tctttgcctt tatgaagccg tttgaaaaga tgaatcggga taccatggaa
     1321 gccaatgcgg ttctgtcttc ttctatcatt gaggacatca acggtattga gactatcaag
     1381 tccttgacca gtgaaagtca gcgttaccaa aaaattgaca aggaatttgt ggattatctg
     1441 aagaaatcct ttacctatag tcgagcagag agtcagcaaa aggctctgaa aaaggttgcc
     1501 catctcttgc ttaatgtcgg cattctctgg atgggggctg ttctggtcat ggatggcaag
     1561 atgagtttgg ggcagttgat tacctataat accttgctgg tttactttac caatcctttg
     1621 gaaaatatca tcaatctgca aaccaagctt cagacagcgc aggttgccaa taaccgtcta
     1681 aatgaagtgt atctagtagc ttctgagttt gaggagaaga aaacagttga ggatttgagc
     1741 ttgatgaagg gagatatgac cttcaagcag gttcattaca agtatggcta tggtcgagac
     1801 gtcttgtcgg atatcaattt aaccgttccc caagggtcta aggtggcttt tgtggggatt
     1861 tcagggtcag gtaagacgac tttggccaag atgatggtta atttttacga cccaagtcaa
     1921 ggggagatta gtctgggtgg tgtcaatctc aatcagattg ataaaaaagc cctgcgccag
     1981 tacatcaact atctgcctca acagccctat gtctttaacg gaacgatttt ggagaatctt
     2041 cttttgggag ccaaggaggg gacgacacag gaagatatct tacgggcggt cgaattggca
     2101 gagattcgag aggatatcga gcgcatgcca ctgaattatc agacagaatt gacttcggat
     2161 ggggcaggga tttcaggtgg tcaacgtcag agaatcgctt tggcgcgtgc tctcttgaca
     2221 gatgcgccgg tcttgatttt ggatgaggcg actagcagtt tggatatttt gacagagaag
     2281 cggattgtcg ataatctcat tgctttggac aagaccttga ttttcattgc tcaccgcttg
     2341 actattgctg agcggacaga gaaggtggtt gtcttggatc agggcaagat tgtcgaagaa
     2401 ggaaagcatg ctgatttgct tgcacaggga ggcttttacg cccatttggt caatagctag
     2461 aaagaggaga ggatgaaacc agaattttta gaaagtgcgg agttttataa tcgtcgttac
     2521 cataattttt ccagtagtgt gattgtaccc atggcccttc tgctcgtgtt tttacttggc
     2581 tttgcaactg ttgcagagaa ggagatgagt ttgtccacta gagctactgt cgaacccagt
     2641 cgtatccttg caaatatcca gtcaactagc aacaatcgta ttcttgtcaa tcatttggaa
     2701 gaaaataagc tggttaagaa gggggatctt ttggttcaat accaagaagg ggcagagggt
     2761 gtccaagcgg agtcctatgc cagtcagttg gacatgctaa aggatcaaaa aaagcaattg
     2821 gagtatctgc aaaagagcct gcaagaaggg gagaaccact ttccagagga ggataagttt
     2881 ggctaccaag ccacctttcg cgactacatc agtcaagcag gcagtcttag ggctagtaca
     2941 tcgcaacaaa atgagaccat cgcgtcccag aatgcagcag ctagccaaac ccaagccgaa
     3001 atcggcaacc tcatcagtca aacagaggct aaaattcgcg attaccagac agctaagtca
     3061 gctattgaaa caggtacttc cttggccggt cagaatctag cctactctct ttaccagtcc
     3121 tacaagtctc agggcgagga aaatccccaa actaaggttc aggcagttgc acaggttgaa
     3181 gcacagattt ctcagttaga atctagtctt gctacttacc gtgtccagta tgcaggttca
     3241 ggtacccagc aagcctatgc gtcagggtta agcagtcaat tggaatccct taaatcccaa
     3301 cacttggcaa aggttggtca ggaattgacc cttctagccc agaaaatctt ggaggcagag
     3361 tcaggtaaga aggtacaggg aaatctttta gacaagggga aaattacggc aagtgaggat
     3421 ggggtgcttc atcttaatcc tgagaccagt gattctagca tggttgcaga aggtgcccta
     3481 ctagcccaac tttatccatc tttggaaaga gaagggaaag ccaaactcac agcctatcta
     3541 agttcaaaag atgtagcaag aatcaaggtc ggtgattctg ttcgctatac tacgactcat
     3601 gatgccggga atcaactttt tctagattct actattacaa gtattgatgc gacagctact
     3661 aagactgaga aagggaattt ctttaaaatc gaggcggaga ctaatctaac ttcggagcag
     3721 gctgaaaaac ttaggtacgg ggtggaaggc cgtctacaga tgattacggg caagaaaagt
     3781 tatctacgtt attatttgga tcaatttttg aacaaagagt aatgttcgtg tttttagagt
     3841 taaataattt ttaaactgtg agaaagattc ttcttgcagt tttttcttta caatttttga
     3901 aaaacatctg ctatttattc ggttaaattc ttgtgttttt tggttttttg tggtaaaatg
     3961 tgctcaagta atacgaaagg cgaactttaa aatgtcaaaa caattgatct attcgggaaa
     4021 agctaaagat atctatacaa ctgaggatga aaatcttatt atttcaactt acaaggacca
     4081 ggcgactgct ttcaatggtg tcaagaagga gcagattgca ggtaagggag tcttgaataa
     4141 tcagatttca tcttttattt ttgagaaatt aaatgcggct ggtgtggcga ctcactttgt
     4201 ggagaaactt tcagacacgg aacaactcaa taaaaaggtt aagattattc ctttggaagt
     4261 cgtgctccgc aactatactg ctggttcctt ttcaaaacgt tttggtgtgg atgagggaat
     4321 cgccttggag actccgattg tcgaatttta ctacaaaaat gatgatttgg atgatccatt
     4381 tatcaatgat gagcatgtga aattcctaca gattgcggat gaccagcaga ttgcctactt
     4441 gaaggaagaa acgcgtcgta tcaatgaact attgaaagtc tggtttgctg agattgggct
     4501 taaattgatt gactttaagc tagagttcgg ttttgacaag gatggcaaga ttatcttggc
     4561 agacgaattt tcaccagata actgccgctt gtgggatgct gatggcaacc acatggataa
     4621 ggatgttttc cgtagaggat tgggagaact aaccgacgtt tatgagattg tttgggaaaa
     4681 gttgcagggt ttaaaataac aacctcaagg ctgtttggga atattgcaag agctgaaata
     4741 aaggaataag aattgatgga taaacgtatt tttgttgaaa aaaaggctga ttttcaggtc
     4801 aagtcagaga gtttggttag agagctccag cacaacttgg gactgtcaag cttgaaaagt
     4861 attcgtattg tgcaagtata tgatgtattt gacttggttg aggacttgtt tgcacctgca
     4921 gagaagcaca ttttctctga gcaggtaacc gaccatgttt tagatgaagt atctgtgcag
     4981 gcggatcttg ctaactatgc tttctttgcc attgaaagtc taccagggca gtttgaccag
     5041 cgtgcagctt cgtcacagga agccttgctt ttgttgggaa gttcgagtga cgtgacagtc
     5101 aacacagccc aactttactt ggtgaataaa gatattgatg cgactgagtt ggaagctgtc
     5161 aaaaactacc tgctcaatcc agttgattct cgtttcaagg atatcacgat agggattgcc
     5221 aagcaggagt tttcagagtc agacaagacc attccaaaat tgcctttctt tgaaagctat
     5281 acagcagaag actttgctcg ctacaaggcc gaacaaggga tggccatgga agtggatgat
     5341 ttgctcttta tccaagacta ctttaagtca atcgggcgcg tgccaactga gactgaactc
     5401 aaggttttgg acacttactg gtctgaccac tgccgtcata cgacttttga gacagagttg
     5461 aaacacatcg acttttcagc ttctaaattt caaaagcaat tgcagtcaac ctatgacaag
     5521 tatattgcca tgcgcgagga attaggtcgg tctgaaaaac cacaaacctt gatggatatg
     5581 gcgactattt tcggtcgtta tgagcgtgct aatggacgat tggatgatat ggaagtctct
     5641 gacgaaatca atgcctgctc agttgaaatt gaagtggacg ttgatggtgt caaggaacct
     5701 tggctcctca tgtttaaaaa cgaaactcac aaccatccaa cagaaattga gccatttggt
     5761 ggagcggcta cctgtatcgg tggagctatt cgtgatccgt tgtcaggccg ttcctatgtt
     5821 taccaagcca tgcgtatttc aggtgctggt gatattacag caccgatttc ggaaactcgt
     5881 gctgggaaat tgccacaaca agtcatttct aaaacagcaa ctcatggtta ttcttcatat
     5941 ggtaaccaga ttgggcttgc cacaacctac gttcgtgaat acttccaccc aggctttgta
     6001 gctaaacgta tggaacttgg tgccgttgtt ggtgcggctc ccaagggcaa tgttgtccgt
     6061 gaaaaacctg aagcaggtga tgtgatcatc cttctcggag gtaaaacagg tcgtgatggt
     6121 gtcggtggtg cgacgggctc ttctaaggtt caaacagttg agtctgtaga gactgctggt
     6181 gctgaggttc aaaaaggaaa tgccatcgaa gaacgcaaga ttcagcgcct cttccgtaat
     6241 ggcaatgtca ctcgtctgat caagaagtcc aatgactttg gggcaggcgg tgtctgtgtg
     6301 gctatcggtg aattggcaga cggtcttgaa atcgacctca acaaggtgcc tcttaaatac
     6361 cagggcttga atggtacaga aattgccatc tctgaatcac aagaacggat ggcggtcgtg
     6421 gttcgtcctg aagatgtgga taccttcgtt gccgaatgta acaaagaaaa tattgatgct
     6481 gttgtggtgg cgacagtaac tgaaaaacca aatcttgtca tgcactggaa tggtgagaca
     6541 atcgttgact tggagcgtcg tttccttgac atcaatggtg tgcgcgtggt tgtcgatgcc
     6601 aaagttgtgg acaaggatgt caaactccca gaagagcgtc aaacatctgc tgaaacactg
     6661 gaatcagata cccttacggt tctatctgac ctcaaccatg caagtcaaaa aggattacag
     6721 actatctttg actgctctgt tggacgctca acggttaatc acccacttgg tggtcgttac
     6781 caactcacac caactgaggc atctgtgcag aaattgccag ttcaacacgg tgtgactcat
     6841 actgcgtcgg tcattgctca aggtttcaac ccatatgtag ctgaatggtc tccataccac
     6901 ggtgctgctt atgcggttat cgaagcaact gctcgtttgg tggctgttgg tgccaactgg
     6961 tccaaggctc gtttctctta ccaagaatat ttcgagcgta tggacaagca agcagagcgt
     7021 tttggtcagc cagtagccgc tcttctaggc tctattgaag ctcagattca acttggcttg
     7081 ccatctatcg gtggtaagga ctccatgtct ggtacctttg aagaattgac cgttccgcca
     7141 accttggttg cctttggggt gacgacggca gatagccgta aggtgctctc tccagaattt
     7201 aaagctgttg gggaaaatat ctactacatc ccaggtcaag ccctctctgc agagattgat
     7261 tttgacttga ttaagaaaaa ttttgctcag tttgaagcaa gccaagctga ccataaagtg
     7321 acatctgcat cagctgtcaa atacggtggt gtagttgaaa gtttggctct tgctaccttt
     7381 ggaaactata ttggtgcaga ggtgaccttg cctgaactta aaacagcttt gacagctcaa
     7441 ttaggcggct ttgtcttcac atctcctgaa gaaattgctg gagtagagaa gattggacaa
     7501 acgaaagcag actttacact gactgtcaac ggtgtgaagc tagatggaca caagcttgac
     7561 agtgcatttc aagggacatt ggaagaagtt tacccaacag aatttaccca agcgaaagaa
     7621 ctagaagaag taccagctgt ggcatcagat gttgtgatta aagccaaaga aaaggttgaa
     7681 aaacctgtgg tttacatccc agtctttcca ggaaccaact cagaatatga ttcagctaag
     7741 gccttcgaaa aagaaggtgc agaggtcaat ttggtgccat tcgtgacctt gaatgaagaa
     7801 gctattgtca agtcagttga aactatggtt gacaatatcg acaagactaa tattctcttc
     7861 tttgctggtg gattctcggc tgcggatgaa ccagatggtt cagctaagtt tatcgtcaat
     7921 atcctgctta atgaaaaagt gcgtgtggct attgatagct ttatcgcccg tggtggtttg
     7981 attatcggta tttgtaatgg attccaagcc ttagtcaaat cgggtctcct accctacgga
     8041 aactttgaag atgctaacaa tactagccca accctcttct acaatgatgc caaccaacac
     8101 gtggccaaga tggtggaaac tcgcattgcc aataccaact caccatggtt ggctggtgtg
     8161 caagtgggcg atatccacgc tattcctgtt tcgcacggtg aagggaagtt tgtcgtgacg
     8221 gctgaggaat ttgcagagct ccgtgacaat ggacaaattt tcagccaata cgttgacttt
     8281 aacggtaaac caagtatgga ttctaagtac aatccgaatg gttctgtcca tgccatcgaa
     8341 ggaattacca gcaagaatgg tcaaatcatc ggtaagatgg gccattcaga acgttatgag
     8401 gacggtcttt tccaaaatat cccaggcaat aaagaccagc acctgttcgc gtcagcggtt
     8461 aaacatttca ctggaaaata agacttacag attttctaat agatagtatc agtaatgtaa
     8521 aagtcatgta aatctagctc ttgatgatta caaatgaaaa ttaggtataa aaaatgacat
     8581 acgaagtaaa atctcttaat gaagaatgtg gtgttttcgg tatttgggga catccagatg
     8641 ctgctaagtt gacctatttt ggactccaca gtcttcaaca ccgtggtcag gagggggcag
     8701 gaatcctctc caatgatcaa ggacaactga agcggcatcg cgatatgggt cttctatcag
     8761 aagtcttcag aaatcctgct aacttagata aattgacggg aactggtgcg attgggcatg
     8821 tgcgttacgc gactgctggc gaagcttctg tagataatat ccagcccttc ctcttccgtt
     8881 ttcacgatat gcagtttggc ttggctcata atggaaatct gaccaatgca gcctctctca
     8941 agaaagaact ggaacaaaga ggagcaattt tcagcgcgac ttcggactct gaaatcttgg
     9001 ctcacctcat tcgtcgcagt cataatccta gcctgatggg caaaatcaag gaagcgctca
     9061 gccttgtcaa aggtggtttt gcctatatct tgctgtttga ggacaagttg attgcggctc
     9121 ttgacccaaa tggattccga ccgctttcga ttggtaaaat ggctaatgga gcagttgttg
     9181 tatcttctga aacctgtgct tttgaggtca ttggtgccga gtggattcgt gatttgaagc
     9241 caggtgagat tgtgatcatt gatgacgagg gcattcagta tgacagctat acagatgata
     9301 cccagttggc ggtttgttct atggagtata tctactttgc tcgccctgat tctaatatcc
     9361 acggtgtcaa tgtccatacg gcacgtaaga gaatgggagc gcaattggcg cgagaattta
     9421 agcatgaggc agatattgta gttggtgtgc ccaattcttc cctaagcgcg gctatgggat
     9481 ttgcggaaga atcaggctta ccaaatgaaa tgggtctgat caaaaaccaa tacacccagc
     9541 gaacttttat ccaaccgact caagaattgc gggagcaagg agtgcggatg aaactgtctg
     9601 ctgtttcggg tgttgtcaaa ggcaaacgtg tggtcatggt ggatgattcc attgtacgtg
     9661 gaacaacctc tcgtcgtatc gttcagctct tgaaagaagc gggtgcgact gaggttcacg
     9721 ttgccattgg aagtcctgca ctagcgtatc catgtttcta cgggattgat atccagaccc
     9781 gtcaggagct gattgcagcc aatcatacgg tcgaagaaac tcgccaaatc attggtgcgg
     9841 acagtatgac ttatctttca attgatggct tgattgagtc gattggtatc gaaacagatg
     9901 cgccgaacgg tggtctctgt gtcgcttact ttgacggtga ctacccaacg cctctctatg
     9961 actacgaaga agactatcgt agaagtttgg aagaaaagac cagtttttac aagtaggcga
    10021 cagattctcc attaaagaaa aggaaaaaac aaatgacaaa taaaaatgca tatgcccagt
    10081 cgggtgtgga tgttgaagcg ggttatgaag ttgttgaacg gattaaaaag cacgtggccc
    10141 gtacggagcg tgcaggtgtc atgggagctc ttggtggctt tggtggtatg tttgaccttt
    10201 ccaagactgg ggttaaagaa cccgtcttga tttcagggac tgacggtgtc ggaaccaagc
    10261 tcatgttggc tatcaagtac gacaagcacg ataccatcgg gcaggactgt gtggccatgt
    10321 gtgtcaacga catcattgct gcaggtgcgg aacccctcta ttttctcgac tacgtagcga
    10381 cagggaagaa tgaaccagct aagctagaac aagtggttgc tggtgtggca gaaggttgtg
    10441 tgcaggctgg tgctgccctc atcggtgggg aaacggctga aatgccgggc atgtacggcg
    10501 aagacgacta tgacttggct ggttttgcgg tcggtgtggc tgaaaaatct caaatcattg
    10561 acggttcaaa ggtggtagag ggagatgttc ttctcggact tgtttcaagt gggattcact
    10621 caaatggtta ctctttggtt cgtcgtgtct ttgcggatta cacaggtgag gaagtcctac
    10681 cagaattgga aggcaagaaa cttaaggaag ttctacttga gccgactcgt atctatgtca
    10741 aggctgtctt gccgctcatc aaagaagagt tggtcaacgg cattgcccac atcacaggtg
    10801 gtggctttat cgaaaatgtc cctcgtatgt ttgcagatga cctagctgct gaaattgatg
    10861 aaagcaaagt tccagtgctt ccaattttca aagcccttga aaaatatggt cagattaaac
    10921 acgaagaaat gtttgaaatc ttcaatatgg gtgtgggact tatgttggcg gtcagccctg
    10981 aaaatgtaga gcgtgtaaaa gaattgttgg atgaagcagt ctatgaaatt ggtcgcatcg
    11041 tcaagaaaga aaacgaaagt gtcattatca aatgaaaaaa atagcggttt ttgcctctgg
    11101 taatggctca aattttcagg tgattgccga agaatttcca gtggagtttg tcttttcaga
    11161 ccatcgtgat gcctatgtgc ttgagcgtgc aaagcagctc ggcgttctgt cctatgcttt
    11221 tgaactcaag gagtttgaga gcaagacaga ctacgaagca gcccttgtcg aactcttgga
    11281 agaacaccag attgacttgg tttgcctagc aggctacatg aaaatcgttg gaccaacctt
    11341 attgtcggct tatgaaggtc ggattgtcaa cattcatcca gcctatttgc cagaatttcc
    11401 aggagctcat gggattgagg atgcttggaa tgctggcgtg ggtcagtctg gtgtgaccat
    11461 tcactgggtg gattcgggtg tggatacagg ccaggtcatc aaacaggttc gtgtgccacg
    11521 actagctgat gataccattg acagatttga agctcgcatc catgaagcag agtacaggtt
    11581 gtatccggaa gtagtgaagg ctctatttac agattgactt tttgatgatt catatgatat
    11641 ctttgatttt aaattggagt cagtgtttgt tgaagacggc ttcaaacgga ggtatttgta
    11701 atgttagaat ctaaaaaaac aactcgatat gtattttatg tctatctgat gttattaact
    11761 tggggaatct tatttaagtt tgaaacaaat cctgaattta tagcattttt cttagctcca
    11821 aggtatatca attggattcc attttcagaa ccactaatag tcgatggaaa aattgttttt
    11881 gctgaaatgt tatttaatct gatttccttt attccattag gtgtttgttt ccctttgata
    11941 aaaactaatt tatctagttt aagaatagtc gggacaggtt tcttgattag tttattgttt
    12001 gagtgcttac agtatatttt agcaataggt ataacagata taacggattt gactttaaat
    12061 acgctaggtg tctgtgtagg cttactgatt tatcaaattt ttataagagt gttcaaatca
    12121 cagactagaa aatggatcaa tatcttaggt atgcttagcc ttggttttgc ttatcttgtt
    12181 ttactgttac tgcatttaat tggtgtttaa ctaatgatta aaaaggagaa tataatgact
    12241 aaacgcgtct taatcagcgt ctcagacaaa gcgggcattg ttgaatttgc ccaagaacta
    12301 aaaaaacttg gttgggagat tatctcgaca ggtggaacta aggttgccct tgataatgct
    12361 ggggtggaga ccattgcgat cgatgatgtg acgggcttcc cagagatgat ggatggccgt
    12421 gttaagactc ttcatccaaa tatccacggg ggtcttctcg ctcgtcgtga tttggatagc
    12481 cacttggaag cagccaatga gaaccaaatt gagcttattg accttgtagt ggtcaacctt
    12541 tatcctttca aggaaacgat tctcaaacca gacgtgacgt acgctgatgc tgtggagaat
    12601 attgatattg gtgggccatc tatgcttcgt tcagcagcga agaatcatgc cagcgtgacg
    12661 gttgtggtag accctgctga ctatacagtg gttttggacg agttgtcagc caatggtgaa
    12721 acgacttacg aaacgcgtca acgtttggca gccaaggttt tccgtcacac agcggcttat
    12781 gacgctttga ttgcagaata cttcacagct caagtgggcg aaagcaaacc tgaaaagttg
    12841 accttgacct atgacctaaa acaagctatg cgttatgggg aaaatcccca gcaggatgcg
    12901 gacttctacc agaaagcttt gccgactgat tactccattg catcagccaa acagcttaac
    12961 ggtaaggaat tgtcattcaa caatatccgc gatgcagatg ctgccattcg tattatccgt
    13021 gacttcaaag accgtccaac cgttgtggct ctcaagcata tgaatccatg tggtatcggc
    13081 caggcggatg acatcgagac ggcttgggat tatgcttatg agtctgaccc agtgtctatc
    13141 tttggtggta tcgctgttct taaccgtgag gtggatgctg cgacagctga gaagatgcac
    13201 ggcgttttcc tcgaaatcat cattgcacca agctatacgg atgaagcgct agccattttg
    13261 atcaataaaa agaaaaactt gcgtatcctt gccttgccat ttaatgctca agaggctagc
    13321 gaagtggaag cagaatacac aggtgtagtc ggtggacttc tcgtgcaaaa tcaagacgtg
    13381 gtcaaggaaa gcccagctga ctggcaagtg gtgaccaaac gtcagccaac cgagacagaa
    13441 gcgactgctc ttgagttcgc ttggaaggct atcaagtacg tcaaatcaaa tggtattatc
    13501 gtgaccaacg accacatgac acttggtgtt ggtccaggtc aaaccaaccg tgtggcttct
    13561 gttcgccttg ccattgacca agccaaagat cgtctggacg gggcggtcct tgcttcagat
    13621 gccttcttcc catttgcgga taacgtggaa gaaatcgcca aagcaggaat taaggccatc
    13681 atccagcccg gtggctctgt ccgtgaccaa gaatccatcg aagcagcgga taaatacgac
    13741 ttgactatgg tctttacagg tgtgagacat tttagacatt aagaagataa aagggaagaa
    13801 aacagtttct ttcctttttt ggcttaaaat gctaactgaa acaagattaa aacgaacttt
    13861 tttgatataa tgttggtaaa taattcgcaa aagaggttga ggaatgaaac tacttgttgt
    13921 cggttctggt ggtcgtgagc atgcgattgc taaaaagtta cttgaatcaa aagacgtgga
    13981 aaaagtcttt gtagctcctg ggaatgatgg gatgactctg gatggtttgg aattggtaaa
    14041 tatctctatt tccgaacatt ctaaattgat tgacttcgca aagaccaatg atgttgcttg
    14101 gacctttatc ggtccagatg atgcccttgc tgctggtatc gtggatgatt ttaaccaagc
    14161 tggacttaag gcctttggtc cgactagggc tgcagcggag ctggagtggt ccaaggattt
    14221 cgccaaggaa atcatggtca aatacggcgt tccgacagca acatatggca cattttcaga
    14281 tttcgaggaa gccaaggcct atatcgaaaa tcatggtgcg cctatcgtag tcaaggcgga
    14341 tggcttggca cttgggaagg gtgtcgtcgt tgctgagacg gttgagcaag cggtcgaagc
    14401 cgctcatgag atgcttttgg acaataaatt tggtgactca ggtgcgcgcg tggttattga
    14461 ggaattcctt gaaggagagg aattttcact ctttgccttt gtaaatggtg ataagttcta
    14521 catcatgcca atggctcagg accacaaacg tgcctatgat ggcgacaaag ggcctaacac
    14581 gggtggtatg ggtgcctatg cgccagtccc acacttacca cagagtgtag ttgatacagc
    14641 ggttgacacc attgtcaagc cagttctaga aggggtgatt aaagaaggtc gcccttatct
    14701 gggagttctt tacgcagggc ttatcctgac agctgatgga ccgaaagtca ttgagttcaa
    14761 cgctcggttc ggagatccag aaactcagat tatcttgcct cgcttgacct ctgactttgc
    14821 tcaaaatatc acagatatcc tggatagcaa ggagccaaat atcatgtgga cggacaaggg
    14881 tgtgactctg ggtgtggttg tcgcatccaa gggctacccg ctagactatg aaaggggcgt
    14941 tgagttgcca gcaaagacag aaggcgatgt catcacctac tatgcagggg ctaagtttgc
    15001 ggaaaatagc agagcactgc tctcaaacgg cggacgagtt tatatgctcg ttaccacagc
    15061 agataccgtc aaagaagccc aagccagcat ctaccaagaa ctatcccaac aaaaaataaa
    15121 aggactcttc taccgaacag atatcggaag caaggcaatt aagtaaagat ataagaataa
    15181 cgcgccgtag tcgccaaaca cgataatggt cgtcgtggtg aaaagaccag aacagtgaat
    15241 gttctggtca gggggaaact tggagacctt aggctcaaag tttaggaatg aaaccgaagg
    15301 tttgcttccg cctccatcac ctaagaccat tatcaaaaag aaaaataaaa attcacaaaa
    15361 tacgttaatg atcgtatggt ttgcgagcgt tagcgagcta atatagaaca atcaccgccg
    15421 ttgtgaaaga acgattggat gataatccaa tcgttcaggg aaattggaag accttgggtt
    15481 tccaatttag gcatgagaca cctttggtgg ctgctgccgt ccctcacaag ctaaggtgat
    15541 tgttgaaaaa gaggaaaaag gagaagaaat gaaaccagta atttccatca tcatgggctc
    15601 aaaatccgac tgggcaacca tgcaaaaaac agcagaagtc ctagaccgct tcggtgtagc
    15661 ctacgaaaag aaagttattt ccgcacaccg tacaccagac ctcatgttca aacatgcaga
    15721 agaagcccgt agtcgtggca tcaagatcat catcgcaggt gctggtggcg cagcgcattt
    15781 gccaggcatg gtagctgcca aaacaaccct tccagtcatt ggtgtgccag tcaagtctcg
    15841 tgctcttagt ggagtggatt cactctattc tatcgttcag atgccgggtg gggtgcctgt
    15901 tgcgaccatg gctatcggtg aagctggagc gactaacgca gctctctttg ccctccgtct
    15961 cctctctgta gaagataggt ccattgcgga tgcacttgcc aactttgctg aagaacaagg
    16021 aaaaatcgca gaggagtcgt caaatgagct catctaaaac aatcggaatt atcggtggcg
    16081 gtcaactggg tcagatgatg gccatttctg ctatctacat gggccacaag gttatcgcgc
    16141 tggatcctgc ggcggattgc ccggcctctc gcgtggcgga aatcattgtg gcaccttata
    16201 acgatgtgga cgccctccgt cagttggcag accgttgcga tgtcctcact tacgagtttg
    16261 aaaatgtcga cgctgacggt ttggatgccg ttatcaagga tggacaactc cctcaaggaa
    16321 cagatctgct ccgcatttcg caaaatcgta tttttgaaaa ggactttttg tcaaacaagg
    16381 ctcaagtcac tgtggcaccc tacaaggtcg tgacttctag cctagacttg gcagatatcg
    16441 acttgtcgaa aaactatgtc ctcaagactg cgactggtgg ctacgatggt catggacaaa
    16501 aggttattcg ttcagaagca gacttggaag cagcctatgc gctagcagac tcagcagact
    16561 gcgtcttgga agaatttgtc aactttgacc ttgagatttc tgtcatcgtg tcaggaaatg
    16621 gcaaggaggt gacgtttttc ccagttcagg aaaatatcca ccgcaacaat atcctgtcta
    16681 agaccatcgt accagcccgc atttctgaaa gtctagcaga caaggctaaa gctatggcag
    16741 tgcgaatcgc agaacaactc aacttgtctg gaactctctg tgtggaaatg tttgcgactg
    16801 atgatgacgt tattgtcaat gaaatcgccc cacgaccaca taactctggg cactattcta
    16861 ttgaagcctg tgatttctct cagtttgaca cccatattct gggtgttctc ggagcaccat
    16921 taccagtcat caaactccat gcgccagccg ttatgcttaa tgtcctcggt cagcatgtcg
    16981 aggctgctga gcaatatgtg acagaaaatt caagcgccca cctccacatg tatggtaaaa
    17041 tagaagcgaa gcacaaccgc aagatgggac atgtgacctt gtttagtgat gtaccggata
    17101 gtgtggatga gcttggggaa gggattgatt tttaggacaa gtctatgata caaattatcg
    17161 ttaatacatt tattgaaaag gataagactg gagcagttgt tgaagtgttg tatgccagtg
    17221 ctgaccaaga taaggtacaa gctaaatatg aagaactagc tgcacaatac cccgaaaatt
    17281 atttagctat ctatgatgta ccgctggata cggatttgaa tacactagat cattacccgt
    17341 ctgtgtttat tgaaaaagag gagtttgagt agaaatcttg gtttacctag atagcttatt
    17401 cccaacagct taagaagaaa ggaaaaatta acacatgatc aaccgttact ctcgccctga
    17461 gatggcgaat atttggagtg aagaaaataa ataccgtgct tggcttgagg tggaaatcct
    17521 ctctgacgag gcatgggctg agttggggga aatccctaag gaagatgtgg ctttgattcg
    17581 caagaaggcg gactttgaca tcgaccgtat tttggaaatt gagcaggaga cgcgccacga
    17641 tgtggtggct ttcacgcgtg cggtttctga gactcttggt gaagagcgca agtgggttca
    17701 ctatgggtta acttctaccg acgtggtgga tactgcttat ggttacctct acaagcaggc
    17761 caacgacatc atccgtcgtg accttgaaaa cttcactaat atcatcgctg acaaggccaa
    17821 ggagcacaag ttcaccatca tgatggggcg tactcatggt gtgcacgctg agccgacaac
    17881 ctttggtctt aaattggcaa cttggtacag cgaaatgaaa cgcaatatcg agcgtttcga
    17941 gcatgcagct gctggtgtag aagctggtaa gatttctggt gcggttggga actttgccaa
    18001 tataccacca tttgtagagg agtatgtctg cgataaactt ggcatccgtg cccaagaaat
    18061 ctctacacaa gtccttcctc gtgaccttca cgctgagtac tttgcggttc ttgccagcat
    18121 tgcgacttca atcgaacgta tggcgactga gattcgtggt ctacaaaaat ctgagcaacg
    18181 cgaagtagaa gagttctttg ctaaagggca aaaagggtct tcagcaatgc ctcacaaacg
    18241 caacccaatc ggttctgaaa atatgactgg tctggcgcgt gtcattcgtg gtcacatgat
    18301 tacggcttat gaaaacgtcg ctctctggca cgaacgcgat atttctcact catcagctga
    18361 gcgtatcatc acaccagata cgaccatttt gattgactac atgctcaacc gttttggaaa
    18421 tatcgtcaag aacttgacag tcttcccaga aaatatgatc cgaaacatga actcgacttt
    18481 tggtcttatc tttagccaac gggctatgtt gacattgatt gaaaaaggca tgacccgtga
    18541 gcaagcctat gacttggtgc aaccaaaaac agcctactct tgggacaacc aagtagactt
    18601 taaaccactt cttgaggcag attcagaagt aacatcacgt ctcactcaag aagaaatcga
    18661 tgaaatcttc aacccagttt attacaccaa acgagtggat gatatctttg aacgtcttgg
    18721 actaggtgat taattaaaaa ataaacagcg agcttcaatc tcgctgttta ttttttatcg
    18781 aaaagactta gtcttctttt cttttagtga gtccataggc tgctagtgtg gacatgagtc
    18841 ctgcgactac tagtcctgca gaatcgtgag ttcctgtttc aggaagtttt ttctctgtta
    18901 ccacaggagc tggatcttga ggaagagctt tgctttcctc agcaggagca gttgatggag
    18961 ctggttgtct tgggatttct agttttggtt tttcttcagc aatagcggct tgtccgtttt
    19021 catcgcctac atgtgttacc atagttccga cttcgactat ttgagtaacg gcttcctgtg
    19081 ctacgacact atttacaagt gttttcactt ccttaccatc ggcagaagtg ctcacagagt
    19141 agaagttgct acgatgtcca ttgacgccct tagtaatgac ttgtgttttt cctttgagta
    19201 agagtggatt ttcacgagtc actgtggtaa atggaatttc ttctttttgg atatccagtc
    19261 taggttttac ctcagtagtt ggtgcaagac cactttcatc acccttgtga gttacaggag
    19321 cgccaacttc aaccacttgg tttataactt ctttggttac ctggctatca aggactgttt
    19381 ctgttgtttt tccattttca gtgagtacag agatgtaatg agttcgttca cctttgactc
    19441 ctgctgtgat aatattttcc tgaccagctg ggaggttagg attttctttc ttgataactt
    19501 caaatggaat ttcttcagtt cttgtgatga gttctggtct ggtttcaaca ttggcagcca
    19561 cttcattttc atctaggctt cctgaatgag ttgcagctgg tttgaggcct tgaagagcgg
    19621 cttttaggtt ggctacaagt gtgtcaagct cagcttgttt attacggttg aggttgtaat
    19681 ttagagctgt tttagctgcg tcaagggcct caagactttc tttactatat ccttctaagt
    19741 ttgtaggaat tttagctaat tcttcgcgga gagcattata attagcacgg aagtagtctt
    19801 tgttgtggtc tgcaaaggca gtcatgagtt caaagatttc ctcttccttg tattcagcgc
    19861 ttggtctatc tgcccagatt gaaagcatac ttccgactgt tggaagatct acttcaggat
    19921 atttggtaga agctagttga ttgaatggtg tttttccagt attctcaata gctttcttga
    19981 ggaaaccacc accatcttct ggtttttgac caagaatgta gtaccagtca ccgttggtat
    20041 tcaagaattt atagcctttg cttgctaggt attgaggtga tgcgaggtta tatccccacc
    20101 agcctttaga ccagtaagaa atcaagacat ctttgtcaaa ctgaacatcg tccttgtctt
    20161 catagtagaa gccatcgttg aaggccattg gttgaagccc tctttctttg gccatagctg
    20221 cgagggtgtt ggcatattcg gcaaatttgc catagagttg ataccacttg aggtagtacc
    20281 agccttgggc actagtcgca tcgttggcgt attcgtcagt accaaagttg aaaatctttg
    20341 ttttacctgc aaagaagtcc atgtatttac cgatgagggc ttttacaaag ttcatcgctt
    20401 cttcgttttt caagtccata gttgtttttg aaactttatc aaagtgggct tgaggatttt
    20461 taatacctaa tttttccatg gcaaccagca tagcatccat gtgacctgga ctgttaatag
    20521 ctgggatgag accaatgtcc ttagatttag cgtattcaat tagctctgtc acttctgcct
    20581 gtgttagtgc agtaccgttt ggatcgtcgt agtaagcttt agttccttcg ataatagctt
    20641 ttttaacgtc atcactagca taggtttttc cgttggcagt aatggtcata tcattgagta
    20701 gaaagcgaag tccgtcattt cctagaagga gatggacatc agaatatccg agctcactgg
    20761 ccttgtctac gatgcgtttg agctggtcca gagtaaagta tttgcgtcca gcatcgattg
    20821 agattacctt gtttttggca agtttttcaa cctcacgttt agcttcttct tctttttgag
    20881 cttcaggcgt gagggtcaag ttgttgacag tttcttgaag tttagcaatg gcttgatcaa
    20941 tcgtatcttg ttgggcacgg ctaaggttgc tatcgagaga gcgaatagct ttttcagctt
    21001 cttttacggc cgcgacgctt tctgcagtat aacggttcag gtcttttggt acctcgttaa
    21061 gtgcttgctc tgcagattca taatcagctg cgaagtattc agcgttggca tttgcaaaat
    21121 gacgcatgag tttgaagagg tgtgatggtg aataacgtgc agatggagtg tcagcccaag
    21181 cagctaccat accaccgatg attgggatat cagctccttc tgtttttggt acagaagtga
    21241 ttggtgtgtt tttaatacca ttgagcccct gatcgagatt gtaccagcct tggccatcag
    21301 cgtttcgtcc aagaacgtag taccaagcat cattggtatt aaggatttgg tgaccttttt
    21361 cagctagtag tttagaagaa gcgacatcgt agcctcccca accaccagtc cacatagaaa
    21421 cgatgatgtc tttgtcaaaa ctaccaaagc ttgtgtcgct attgtagtag ataccgtcgt
    21481 taaaggccat tggtttgaga ccgtgcgatt ttacaatacg agcgaggtca ttggcgtagg
    21541 caataaattt ttcatagcct tttacagggt agccttcgtt tggatagtat ttatcagctt
    21601 gaagcacact ccaaccttta gcatctgtcg catcattggc atattcatca agtccgatgt
    21661 tgaagatttc agtctttttc gcgaaataag cagcatactt gtcgataagg gcttttgtaa
    21721 aagcgacagc ttgttcgttg tcaagatcga cagtacgggc tgattccttc ccaaaatagc
    21781 taaagttagg gttttggatt cccaattctt tcatggcatt gagaatcgca tccatgtgac
    21841 caggactatt tactgtcgga atgagaccga tacctttatc ttttgcatag ttaatcagat
    21901 ctgtcatttg actttctgtt aagtgattgc cgtttggatc gttgtaataa tcatttgtac
    21961 ctttttcaat ggcgcgtttg acatcgtcac tggcataggt cttgccgtta gctgtgatgc
    22021 tcatatcgtc caacatgaaa cggagtccat catttccgac taataggtgt aaatcagtgt
    22081 agccataatg tttcgcttta tcgatgattt ccttgagctg ttctggtgag aaatatttac
    22141 gtccagcatc aatagaaaca attttctttt tcgctagttt ttcacttaca gttgcagcac
    22201 gttcctttcc tgcctctgtt gccggtttgt cagcctctgc tttcgcttca tcttttttag
    22261 ctggtttatc ctttttaggg ctagcttctt ctgccttttt attagcagtt tctttttcag
    22321 cagaagttgg agttaccact tctgctttat cactaggagt tgaactaact tcctcttgtg
    22381 gtttttcttc tgtttttgga agactagcta ccttatcagt agctggagtt tctgtttcta
    22441 cagtttttgg agcttctggt tgaagctctg ctttaggtgt ttcctcagtc cgattttcgg
    22501 atgattgagg ggaatcagaa accgtatgga tggtcggttg gttttctgta gtagtaggag
    22561 taactccatc ggctgcaaca gtctgtgctt ggaaggcaaa tccaattaga acagaagctg
    22621 ctcctacagc gtatttacga atagaaaaac gctgttgttt ttcatgtttc attgcaaaac
    22681 ctcctgattg cattgttata ttgatagcga ttatataaat caacgccttt attttatttc
    22741 ttgttttaac gagagtcaag aggagatgac aaaaaactat aataagtata aaaaaatata
    22801 aaatttaaac ttaagatttc agattggtcg aaaaaataca tatatatatc tagtataatt
    22861 tttggttcta tttctataaa atattccaca aattatagaa tcttccaaaa ataggtaagc
    22921 gctacctttt tggtgtggta taataagcat agaaaaagcc cgagcgatta ggctcaggct
    22981 ttcttcttag tgatcacggt cacatgagat gaatttaatc ttgtagtaat cagatcgttt
    23041 gtaagtttca ctgtattcta aaacttggcc agttgattcg agtttggtga ttttagtttg
    23101 taggacagta gggaattgtt catcgactcc gaggactgaa gccgcatgtt ctggagttgg
    23161 aaagactatt tcgttgattt cttcaaagtg ttcatcattc atgtgaatgt ggtagtctaa
    23221 cttgaaacga ttatagatag aactatagta ttcaaggttt ggataatttg cgttgatata
    23281 ttgttctggg atgtaggatg tatggtagat ataaacgaca ccgtttgatt cgcggatacg
    23341 ttcaatcttg tagtagaatt gatcgccgcg tagacccaat ttttccaagt aaacaagctt
    23401 gtttccgcgt tcaattgaaa gaacagttac cttatcatct ttagcattga agagttcaat
    23461 atctgaaaac tctacaagct tgtgtttgcg tgcacgtgaa acgaaggttc cttttccttg
    23521 ttggcggaca atatagccat ctttggcaag gtcgtttaag gcgcgaacaa ctgtgataga
    23581 gctgacatcg tacattgaaa tgagttctgc ttcagtgtaa aatttatctc cactgctaaa
    23641 ctgcccagag atgattttat tttttaattc gtcttttatg tattgatatt tgggaattgc
    23701 catattttta cctctatttt ccttctccat agaaaatttt accataaaag cgaaaaaaat
    23761 agtagtcttt tgaataaaaa attagaataa tagtttgaaa aattaagcga tatagggatt
    23821 gctcatattt tatcaatgta ttctatacaa aattatttta gatcctatat tccgaattta
    23881 aagagcgttt gaaatgggtc taaaaatgtt tgaaactaat tgaatgtgtg tataatagta
    23941 aaaatgcagt aaatatcccg acaatttcta ttgacaattc aaacagattg gtttatgatt
    24001 aatataacaa caaatgaaat cgcaaacttt cgcggtcgga aggtagtttt atgacacgat
    24061 ttgagatacg agatgatttc tatctcgatg gaaaatcatt taagatttta tctggtgcca
    24121 ttcattattt tagggttcct ccagaggatt ggtatcattc gctctataac ttgaaggctc
    24181 ttggttttaa tacggtagag acttatgttg cttggaattt acacgagcct cgtgaaggtg
    24241 agtttcattt tgaaggtgat ctggatttag agaaatttct ccaaatagcg caggatttgg
    24301 gtctctacgc aattgtgcgt ccgtctccat ttatctgtgc ggaatgggaa ttcggtggct
    24361 taccagcttg gctcttgacc aagaacatgc gaattcgctc atccgaccca gcatatatcg
    24421 aggcagttgg tcgctactat gatcagttat tgccaagact ggtgcctcgt ttgttggaca
    24481 atggtggcaa tattctcatg atgcaggttg aaaatgagta tggttcttac ggagaagata
    24541 aggcttacct gagagcgatt cgacagctaa tggaagagtg tggcgtaacc tgtcccctct
    24601 ttacatcaga tggtccatgg cgagctactc tgaaagctgg aaccttaatt gaagaggacc
    24661 tctttgtaac aggaaacttt ggttctaagg caccttacaa cttttcgcag atgcaggaat
    24721 tctttgatga acatggtaag aaatggccac tcatgtgtat ggagttctgg gatggttggt
    24781 tcaatcgctg gaaagaaccg attatcacac gggatcctaa ggaattggca gatgcagttc
    24841 gagaggtttt ggaacaaggc tctatcaatc tttacatgtt ccacggtggt acaaactttg
    24901 gtttcatgaa tggttgctca gctcgaggaa ctttggacct gccacaagtt acgtcttatg
    24961 attacgatgc ccttctggat gaagaaggaa atccaactgc taaatatctt gcagtcaaga
    25021 agatgatggc aacacatttt tcagagtatc cgcagttgga accactctac aaagagagta
    25081 tggagttgga tgctattcca ctagttgaaa aagtttcttt gtttgaaacc ttagatagct
    25141 tgtcaagtcc tgtagaaagt ctctatcctc aaaagatgga ggagctggga caaagttatg
    25201 gctacctact ttatcgaaca gaaacaaact gggatgcaga agaagaaaga cttcgtatca
    25261 ttgatggtcg agatagggcc cagctgtatg tcgatggtca gtgggttaaa actcaatatc
    25321 agacagagat tggggaagat attttttatc aaggtaaaaa gaaatggcta tctaggttag
    25381 atatcttgat agaaaatatg gggcgtgtca actatgggca taagttctta gcggatacgc
    25441 aacgtaaggg aattcggaca ggggtctgta aggatctgca tttcttacta aactggaaac
    25501 actatccact cccactagac aatcctgaga aaattgattt ttcaaaagga tggactcaag
    25561 gacaaccagc cttttacgct tatgacttta cagtcgaaga gccaaaagat acttacctag
    25621 acttgtctga gtttggtaag ggggttgcct ttgtcaatgg gcagaatcta ggacgttttt
    25681 ggaacgttgg cccaactctc tcactttata tccctcatag ctatctcaag gaaggtgcca
    25741 accgcatcat tatctttgaa acagaaggtc aatataaaga agagattcat ttaactcgta
    25801 aacctacact aaaacatata aagggggaaa acttatgaca attgtaggat gccgtattga
    25861 tggacgtttg atccacggac aagtagccaa tctttgggct ggaaaactaa atgtttcacg
    25921 cattatggtt gtagacgacg aagttgtcaa caacgatatt gaaaagagtg gtttgaaact
    25981 tgcgacacca ccaggtgtga aattgagtat tttgccagtt gagaaagctg cagccaatat
    26041 tcttgctggc aaatacgata gccaacgtct ctttatcgtg gctcgtaaac cagaccgctt
    26101 ccttggtttg gtagaagcag gtgtaccact tgaaaccctt aatgttggga atatgtctca
    26161 aacaccagaa actcgttcta ttacacgttc tatcaacgta gtagacaagg atgtggaaga
    26221 cttccacaaa ctggcagaaa aaggtgttaa acttactgct cagatggttc caaatgatcc
    26281 aatttcagac tttttgagct tattaaaata ggaaaaaatt ttttaggagg tcattgttat
    26341 gatacaatgg tggcaaattt tacttctcac tttgtactca gcttatcaaa tctgtgatga
    26401 gttgacgatc gtttcatctg caggttcccc tgtatttgct ggtttcatta ctggtttaat
    26461 catgggagat gtgactactg gtttacttat cggtggtaac ttgcaactgt tcgttcttgg
    26521 ggttggtacc ttcggtggtg cttctcgtat cgacgcaact tctggtgcgg ttcttgcgac
    26581 agccttctct gtttcacaag gaattgatgc accgcttgca attactacaa tcgctgtacc
    26641 agtagcagct ctcttgactt acttcgacgt tcttggtcgt atgactacta ccttcttcgc
    26701 tcaccgtgtg gatgctgcaa tcgaacgctt tgactataaa ggtattgaac gcaactactt
    26761 gcttggtgcg attccgtggg ctctatctcg tgcccttcca gtcttctttg cccttgcttt
    26821 tggtggtgcc tttgtacaat cagtagtaga cttcgttgaa gcctacaaat gggttgcaga
    26881 tggcttgaca cttgcaggac gtatgcttcc aggtcttgga tttgcaatct tgcttcgtta
    26941 ccttccagtt aaacgtaacc ttcactacct tgctatggga tttggtttga cagctatgtt
    27001 gactgttctt tactcatatg taacaggtct tggtggcgct gttgctggta tcgtaggtac
    27061 tcttcctgct gaagttgctg aaaaaattgg tttcgtgaac aacttcaaag gtttgtctat
    27121 gattggtatt tctatcgtag gtattttcct tgcagtgctt cacttcaaaa atagccaaaa
    27181 agtagctgta gcagcacctt ctacaccatc agaaagtggg gaaatcgaag atgacgaatt
    27241 ctaattacaa acttacaaaa gaagatttta atcaaatcaa caaacgtagc ttgtttactt
    27301 tccaattagg ttggaactac gaacgtatgc aagcttctgg ttacctttac atgatcttgc
    27361 ctcagttgcg taaaatgtat ggtgatggaa ctcctgaatt gaaagaaatg atgaaagttc
    27421 atactcaatt cttcaatact tcaccattct tccataccat tatcgctggt tttgaccttg
    27481 ccatggaaga aaaagatggt gtaggttcaa aagacgctgt taacggtatc aagacaggtt
    27541 tgatgggacc attcgctcct cttggggata caatctttgg ttcacttgta cctgctatca
    27601 tggggtcagt cgcagcaact atggctatcg ctggccaacc ttgggggatc ttcctttgga
    27661 ttgcagttgc agtagcgtat gacatcttcc gttggaaaca gttggaattt gcttacaaag
    27721 aaggggttaa ccttatcaac aacatgcaaa gtaccttgac agctttgatt gacgctgcat
    27781 ctgtacttgg tgtcttcatg atgggtgctc ttgtagcaac agtgattaac tttgaaattt
    27841 cttacaagtt gccaatcggt gaaaagatga ttgatttcca agacatcttg aaccaaatct
    27901 tcccacgttt gcttccagca atctttactg cctttatctt ctggttgctt ggtaaaaaag
    27961 gtatgaactc tactaaagct atcggtatta ttatcgtact tgctttggct ctttctgccc
    28021 ttggtcactt tgcacttgga atgtaattcc ttatgactaa atcattaatt ttggtgagcc
    28081 atggtcgctt ctgtgaggag cttagaggta gcacagaaat gattatgggc ccacaagaca
    28141 acatttacac agtagctctt cttccagaag atggcccaga agaatttact gctaaatttg
    28201 aagctgttat tgaaggattg gatgatttcc tagtctttgc ggatcttctc ggtgggacac
    28261 cttgtaatgt ggtgagtcgc ttgatcatgg aaggtcgtga tattgacctt tacgcaggga
    28321 tgaatcttcc aatggtgatt gaatttatca atgcgagcct tacaggcgca gatgcggact
    28381 acaagagccg tgctgcagaa agcattgtga aagttaatga cctgttagcg ggcttcgatg
    28441 atgacgaaga tgaataatac tcttcgaaaa tctcttcaaa ctacgtcaac gtcgccttgc
    28501 cgtaggtata tgttactgac ttcgtcagtc ttatccggca acctcaaaac ggtgttttga
    28561 gctgacttcg tcagtcttat ccggcaacct caaagcagtg ctttgagcag cctgcggcta
    28621 gtttcctaca gattttagtt ggaactcgat tcaattcatg tgacaacgtg aaaatcgtta
    28681 gagcatttta tatagaatat acatgggaat ggagcttact cccattccca tatttaatag
    28741 aaaaagagga actcaatgct acattataca aaagaagact tgctcgaatt gggtgcagaa
    28801 atcactacgc gtgaaatcta ccaacagcct gatgtatgga gagaagcttt tgaattttat
    28861 caagcaaaac gtgaagaaat tgcagccttt ctacaagaaa tcgctgataa acatgactat
    28921 attaaggtta tcttgacagg tgctgggact tctgcttatg tgggagatac cttgctacct
    28981 tactttaagg aagtctatga cgaacgcaaa tggaatttca atgctattgc gacaacagat
    29041 atcgttgcca aaccagcaac ctatttgaaa aaagatgtgg caactgtcct tgtgtctttt
    29101 gctcgtagtg ggaactcgcc tgaaagtgtg gcgactgttg atttggccaa atccttggtg
    29161 gatgagcttt atcaagtgac gattacttgt gcagcagatg gtaaattggc tcttcaagct
    29221 cacggtgatg accgtaatct cttgctcttg caaccagctg tctctaatga tgctggattt
    29281 gccatgactt ctagctttac gtctatgatg ttgacagctc tcttggtctt tgatcctaca
    29341 gaatttgctg ttaagtctga acgttttgaa gttgtatcta gtcttgcccg taaagtttta
    29401 gacaaggtag aagatgtcaa agagctcgtt gatttagact ttaaccgtgt catctatcta
    29461 ggcgctggtc ctttctttgg acttgctcat gaagctcagc tcaagatttt ggaattaact
    29521 gctggtcaag ttgcgaccat gtatgaaagc ccagttggct tccgtcacgg tccaaaatct
    29581 cttatcaacg acaatacagt tgttttggtc tttggtacaa cgacagccta cactcgtaag
    29641 tacgacttgg acttggttcg tgaagttgct ggtgaccaga ttgctcgtcg tgttgtgctt
    29701 ttgagtgatc aagcttttgg tcttgaaaat gtcaaagaag tggcccttgg ttgtggcggt
    29761 gtcttgaatg atatttaccg tgtcttccct tacatcgttt atgcccaact ctttgcccta
    29821 ttgacttcac tcaaggtaga aaataaacca gatacaccgt ctcctacagg tacagtaaac
    29881 cgtgtagtac aaggtgtcat aattcacgaa tatcaaaagt aagacagtgt ttatgaattc
    29941 ttgacaagag gatttgtaaa ttatcagata aaccatagat tgtcagtacg ctttctatgg
    30001 tttgtttgct tgagagaaat agtaaaagga gaacagaatg aaagcataca cagagcgtgt
    30061 atttggaaat gttgagggcg aggatgtctt ggcctatcga tttgagacag acggtggcta
    30121 ccaacttgag gttatgactt atggcgcgac catcttgcgc tatgtcgcac ctgacaaggc
    30181 tggaaatttt gccaatgtta tcttgggatt tgatgacttt gatagttatg taggcaatag
    30241 tcccaagcat ggagcaagtg taggtcctgt agcgggtcgt attgcaggtg cgacctttga
    30301 gctcaatggt aagacctatg accttgaggt taataatgct agcaactgta atcacagtgg
    30361 ttcaactggt tgggattcca gcttgtttga agttgaagaa gtaagcgatc atggcttgac
    30421 tctctacaca gagcgtacag atgggacagg agggttccct ggaaatctca agatttggat
    30481 cagttatcac ttggaagaaa ctggtgccta tgaaatcatc tacaaggtaa cgaccgatca
    30541 ggatacgctg gtcaatccaa ccaaccacag ctatttcaac ttgtctggtg atttcacgca
    30601 gacgattgac cgtcatgtct tccaactaaa cacagagggc atttactcaa tcgctcctga
    30661 cggtgttcct gccaaaactc cagaagccaa ccgtgatgtg gtcaaacaca tctacaatgg
    30721 taccttgttg aaggatatct ttgcagaaga agatgagcaa atccagctgg catcaggttt
    30781 ggatcaccca tttgcccttc ctgcaggcca tgacaatgct ggattccttt atgaccaaaa
    30841 ttcaggtcgc ttcctgcttt tcaagacaga agctccttgc tttgtggtct acacagcaaa
    30901 ctttgtggat gaaagtgtca tcataggagg tcagccaatg ctacagcaca atgggattgc
    30961 tcttgaagcg caagctttac cagatgccat tcacagtgac cttaaaggcc aagtcattct
    31021 taaagctggt caaaccttca ccagtaagac acgttatgaa cttgttgtga aataaaaaaa
    31081 gctggtcaaa aagtctttaa aattaaaata acgcatattg tcaggtgatg aaaagtttga
    31141 taatatgcgt tttattatga aatgatttac tttatcttat cctgaaatgg tgttattttt
    31201 gagttatctg gcttgacttt cttgatggaa attatataat agttgtaata acaataatta
    31261 caacgagaaa agaggaccat ttatgaccta tgaatacaag agtcacattt atttggcaga
    31321 gacagtttta aatgtaaagg atttggccag tcaaacagcc ttttatcagc aagttattgg
    31381 tttagaaatc ttatctcaaa ctgagacaga gtccattcta ggccttggtg gaaaagtctt
    31441 ggtacagctg attcaagcac aagagagcgg agaagtgagg gaacattatg gtctttacca
    31501 tttggccatt ctcttgccca cacgcaaggc tttggctgat gtcttgaaac acctgacaga
    31561 tttgcaaatt cctcttgtcg gcggtgcaga ccatggttac agtgaagcta tttacttgga
    31621 agatttggag ggaaatggca ttgaactcta tcgagataag ccagtttcca catggaatat
    31681 tcgagaagat ggacgcatta tcggagtgac ggaggctctt gcggcgcagg acatttatga
    31741 gttgggggaa agagtagagc cctttatcct ggcagaaggt acaagaatgg ggcatattca
    31801 tctttccgtc aaggatagtc gaaagtccag ccagttttat caaaaggtgt tagggctaga
    31861 gaataaattc agtgtgcctg gcgctagttg gattgcggct ggagattacc atcatcattt
    31921 agcagttaac gaatggggag gaaaaggtct ggcttcgcgt aagcaaggct taccaggttt
    31981 agcctactat gtcatcgaag tcgcacacaa aaaagaacta ttaacgattg cccaacgagc
    32041 acaagaagtt gacgcaccaa tcaaatggat gacatcgagc caattggaaa tcacagactc
    32101 agatggcatc gtgacccgta ttcgtttagc aaggtaaaat taggaatttt taataagtta
    32161 taagtattgc tagtttgctt tttgaacggt ctttggtaac agaactgcgt gagctggatg
    32221 ggtgagaatt ttgacaaaga agctgattag agatataatg aagaaaaatc gagcaaggaa
    32281 aaagaaatga caaattcaaa gtatattact tgtttgaaac gttcagaggg ccagttgtgt
    32341 gggattcaaa agatgattga aggagattgt gactgtgctg atattgtgac gcaactgaca
    32401 gcagtgagat ctagtgtaga gcgcgtgatt gagatgataa ttaccgaaaa tcttactgaa
    32461 tgtatcaatc agcccctaga tgattctgaa gctcaaaagg aacgcctaga aaaggctatc
    32521 cgatacttga ttaaacggaa ataaatgaat gttttgagac gatatgtgca aaggtctatt
    32581 aactattaga atagtttaat gtgagtcaaa agaagttgta aaaaatcttt aaaattaaaa
    32641 aaacgcatag tatcaggtgt tgaatgtact gaccccaaaa agttagattt tttctgtcta
    32701 acttttgggg tgcagttcat aagaaccttg gtaatatgcg ttttattatg tagagactta
    32761 tactcttcga aaatctcttc aaaccacgtc agtttcacct tgccgtagat atggttactg
    32821 acttcgtcag ttctatctac aacctcaaaa cagtgttttg agctgacttc gtcagttcca
    32881 tccacaacct taaaacagtg ttttgagcag cctgcggcta acttcctagt ttgcacttta
    32941 attttcattg agtattactt catcttctcc tgaaattgag tttttgccca gctcctcttg
    33001 attattctac ttgaccgggc caagcattca taccaccttc tacgttggta acggtgaggc
    33061 cttgggagct gagaaattgg caggtagatg cagagcggac tcctccttga caaataacat
    33121 agtattcatg gtcaggtttg agttctttgt agccttgctc taaggtactt aatggaagat
    33181 ttttggcacc tggtgcatgt cctgcttgga attcatgtgc ttcacggaca tcgataagtt
    33241 ctagattttc attttggtat tttccataaa agtcagccat gctgatacta gtttccatat
    33301 tctactcctt ctgggttaac cattttgtat agtgaataag cgccgtcaag gttttgggcg
    33361 gtaaatcctg cttgcttgag gataggctct gcgatatagc tgcgcaaacc actgtggcag
    33421 ctgacgatgt aggcttgttt tttgtccagt tcatcagctt cctccttgac actttgtcag
    33481 tttttgatac aatagtacaa aattagagga ggcaggctat gattcagaaa catgcgattc
    33541 ctattttaga gtttgatgac aatcctcagg cggttatcat gcccaatcac gaggggttgg
    33601 acttgcagtt gccaaagaag tgtgtctatg cttttttagg tgaggagatt gaccgctatg
    33661 cgagggaagt aggggcgaac tgtgttggcg aattcgtttc tgctaccaag acctatccag
    33721 tctatgtcat caactacaag ggtgaggagg tctgtctggc tcaggctcct gttggctccg
    33781 ctccagcagc ccagtttatg gattggttga ttggctatgg tgtggagcag attatctcta
    33841 ctgggacctg tggtgtccta gctgatatag aggaaaatgc ctttctagtc cctgttcgcg
    33901 ctttgcgaga tgagggagcc agttaccact atgtggcacc ttgtcgttat atggaaatgc
    33961 agccagaggc tattgctgct attgaggaag ttttggaaga cagagggatt ccttatgaag
    34021 aagtcatgac ctggacgaca gacggttttt accgagaaac ggctgaaaag gtggcttatc
    34081 gtaaggaaga aggctgtgct gttgtggaga tggagtgttc tgctcttgcg gcagtagctc
    34141 aattgcgtgg ggttctctgg ggtgaattgt tgttcacagc agattctcta gcggacttgg
    34201 accagtacga cagtcgtgac tggggctcgg aagcttttaa taaggcgcta gaactgagtt
    34261 tagcaagtgt tcaccacctt tagttgtaca ggcaaaggat ttgttttatc ataaaatgtc
    34321 tagatcatac ttttcaaaaa tatgtttaaa cgaggtcacc ttcctcttgt cctaggcatg
    34381 ttgaggttgg gaaaaatctt taaaatcaga aaaacgtatc atatcaggtg atgaaaattt
    34441 tgatactatg cgttttatgt tggtaagatt tagagtgaga tgaaatgata ctcttcgaaa
    34501 atctcttcaa accaggtcag cttcaccttg ccgtatagat gttactgact tcgtcagttc
    34561 tatctgcaac ctcaaaacag tgttttgagc tgacttcgtc agttctatcc acaacctcaa
    34621 aacagtgttt tgagcaacct gtgactagct ttctaagcga tgccttggtt ctcattgcct
    34681 ataatcaaaa agagaaattt tctcctgaaa agcatataga gtagctggcg ttaaaagctc
    34741 ctgtcttgct tttttgatct atagtcacat ctatcaagta ttgttcttgc ctaagctatc
    34801 aataaaaagg tggcattttt taggcttggt gttagtgaat tttgccttat cctatctaag
    34861 tcatttcgag ctttttatgg tacaatggaa acatgttatt caaattatct aaggaaaaaa
    34921 tagagctagg cttatctcgt ttatcgccag cccgtcgtat ttttttgagt tttgccttgg
    34981 tcattttact aggctctctt cttttgagct tgccctttgt ccaagttgaa agctcacgag
    35041 cgacttattt tgatcatctt ttcactgctg tctctgcagt ctgtgtgaca ggtctctcaa
    35101 cccttccagt agctcacacc tataatatct ggggccaaat aatctgtttg ctcttgattc
    35161 agatcggtgg tctagggctc atgactttta ttggggtttt ctatatccag agcaagcaga
    35221 aacttagtct tcgtagccgt gcaactattc aggatagttt tagttatgga gaaactcgat
    35281 ctttgagaaa gtttgtctat tctatttttc tcacgacctt tttggttgag agcttgggag
    35341 ctattttgct tagttttcgc cttattcctc aacttggctg gggacgtggt ctttttagtt
    35401 ccatttttct agcgatctca gccttctgta atgccggttt tgataattta gggagcacca
    35461 gtttatttgc ttttcagacc gatttactgg tcaatctggt gattgcaggc ttgattatta
    35521 caggcggcct tggttttatg gtctggtttg atttggctgg tcatgtagga agaaagaaaa
    35581 aaggacgtct gcactttcat acgaagcttg tactattatt gactataggt ttgttgttat
    35641 ttggaacagc aactactctc tttcttgagt ggaacaatgc tggaacgatt ggcaatctcc
    35701 ctgttgccga taaggtttta gttagctttt ttcaaacagt gacgatgcga acagctggct
    35761 tttctacgat agattatact caggctcatc ctgtgactct tttgatttat atcttacaga
    35821 tgtttctagg tggggcacct ggaggaacag ctgggggact caagattacg acattttttg
    35881 tcctcttggt ctttgcacga agtgagcttc taggcttgcc tcatgccaat gttgcgagac
    35941 gaacgatcgc gccgcgaacg gttcaaaaat cctttagtgt ctttattatc tttttgatga
    36001 gcttcttgat aggattgatt ctgctaggga taacagccaa aggcaatcct ccctttatcc
    36061 acctcgtatt tgaaaccatt tcagctctta gtacagttgg tgtaacggca aatctgactc
    36121 ctgaccttgg gaaattggct ctcagtgtta tcatgccact tatgtttatg ggacgaattg
    36181 gtcccttgac cttgtttgtt agcttggcag attaccatcc agaaaagaaa gatatgattc
    36241 actatatgaa agcagatatt agtattggtt aagaaaggaa agagcatgtc agatcgtacg
    36301 attggaattt tgggcttggg aatttttggg agcagtgtcc tagctgccct agccaagcag
    36361 gatatgaata ttatcgctat tgatgaccac gcagagcgca tcaatcagtt tgagccagtt
    36421 ttggcgcgtg gagtgattgg tgacatcaca gatgaagaat tattgagatc agcagggatt
    36481 gatacctgcg ataccgttgt agtcgcgaca ggtgaaaatc tggagtcgag tgtgcttgcg
    36541 gttatgcact gtaagagttt gggggtaccg actgttattg ctaaggtcaa aagtcagacc
    36601 gctaagaaag tgctagaaaa gattggagct gactcggtta tctcgccaga gtatgaaatg
    36661 gggcagtctc tagcacagac cattcttttc cataatagtg ttgatgtctt tcagttggat
    36721 aaaaatgtgt ctatcgtgga gatgaaaatt cctcagtctt gggcaggtca aagtctgagt
    36781 aaattagacc tccgtggcaa atacaatctg aatattttgg gtttccgaga gcaggaaaat
    36841 tccccattgg atgttgaatt tggaccagat gacctcttga aagcagatac ctatattttg
    36901 gcagtcatca acaaccagta tttggatacc ctagtagcat tgaattcgta aagagggatg
    36961 acccctcttt tttgatgcct aagatggcaa atagagacag aagccccttg tcttctagta
    37021 aaagttcttc aaaggctgga ctttatggta aaatagaaag aagtgacaag agagagtaat
    37081 actcaatgaa aatcaaagat caaactagga aactagctac gggctgctca aaacactgtt
    37141 ttgaggttgc agatagaact gacgaagtca gtaacatcta tacggcaagg cgacgttgac
    37201 gcggtttgaa gagattttcg aagagtataa gaaaaaatca gtcccctaaa ggagtagatt
    37261 atgaagttat tgtctatcgc aatttctagc tataatgcag cagcctatct tcattactgt
    37321 gtggagtcgc tagtgattgg tggtgagcaa gttgggattt tgattatcaa tgacgggtct
    37381 caggatcaga ctcaggaaat cgctgagtgt ttagctagca agtatcctaa tatcgttaga
    37441 gccatctatc aggaaaataa atgccatggc ggtgcggtca atcgtggctt ggcagaggct
    37501 tctgggcgct attttaaagt agttgacagt gatgactggg tggatcctcg tgcctacttg
    37561 aaaattcttg aaaccttgca ggaacttgag agcaaaggtc aagaggtgga tgtctttgtg
    37621 accaattttg tctatgaaaa ggaagggcag tctcgtaaga agagtatgag ttacgattca
    37681 gtcttgcctg ttcggcagat ttttggctgg gaccaggtcg gaaatttctc caaaggccag
    37741 tataccatga tgcactcgct gatttatcgg acagatttgt tgcgtgctag ccagttctaa
    37801 ctgcctgaac atacttttta tgtcgataat ctctttgtct ttacgcccct tcagcaggtc
    37861 aagaccatgt actatctgcc tgtcgatttc tatcgttatt tgattgggcg tgaggaccag
    37921 tctgtcaatg agcaagtgat gattaagtgc attgaccagc aactcaaggt caatcgactc
    37981 ttgatagacc aacttgattt gtcccaagtg agtcatccca aaatgcgaga atatctgctg
    38041 aatcatattg aactcacgac ggtgatttcc agtaccctgc tcaaccgatc tggaacagcg
    38101 gagcatctgg caaaaaaacg ccaattgtgg acctatattc agcagaaaaa tccagaagtc
    38161 tttcaggcta ttcgtaagac catgttgagc cgtttgacca aacattctgt cttgccagat
    38221 cgcaaactgt ccaatgtcgt ctatcaaatc accaaatctg tttatggatt taattaatat
    38281 aagtgtttta taagagggat ttaagaaaaa ttttaacttt ttcttagtcc tttttaattt
    38341 caggagatta tactagagtc atcaaataaa gaaagactct aaggagaatc ctatgaaatt
    38401 caatccaaat caaagatata ctcgttggtc tattcgccgt ctcagtgtcg gtgttgcctc
    38461 agttgttgtg gctagtggct tctttgtcct agttggtcag ccaagttctg tacgtgccga
    38521 tgtggtcaat ccgaccccag gtcaagtctt acctgaagag acatcgggaa cgaaagaggg
    38581 tgacttatca gaaaaaccag gagacaccgt tctcactcaa gcgaaacttg agggcgttac
    38641 tggaaatacg aattcacttc cgacacctac agaaagaact gaagtgagcg aggaaacaaa
    38701 ctcttctagt ctggatacac tttttgaaaa agatgaagaa gctcaaaaaa atccagagct
    38761 aacagatgtc ttaaaagaaa ctgtagatac agctgatgtg gatgggacac aagcaagtcc
    38821 agcagaaact actcctgaac aagtaaaagg tggagtgaaa gaaaatacaa aagacagcat
    38881 cgatgttcct gctgcttatc ttgaaaaagc tgaagggaaa ggtcctttca ctgccggtgt
    38941 aaaccaagta attccttatg aactattcgc tggtgatggt atgttaactc gtctattact
    39001 aaaagcttcg gataatgctc cttggtctga caatggtact gctaaaaatc ctgctttacc
    39061 tcctcttgaa ggattaacaa aagggaaata cttctatgaa gtagacttaa atggcaatac
    39121 tgttggtaaa caaggtcaag ctttaattga tcaacttcgc gctaatggta ctcaaactta
    39181 taaagctact gttaaagttt acggaaataa agacggtaaa gctgacttga ctaatctagt
    39241 tgctactaaa aatgtagaca tcaacatcaa tggattagtt gctaaagaaa ctgtcgaaaa
    39301 agctgttaaa gataacgtta a
//
LOCUS       DBERXF010000018        38485 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.18, whole genome shotgun sequence.
ACCESSION   DBERXF010000018 DBERXF010000000
VERSION     DBERXF010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 38485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38485
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.18"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(38..1522)
                     /locus_tag="ACL8JK_001034"
     CDS             complement(38..1522)
                     /locus_tag="ACL8JK_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator PRD
                     domain-containing protein"
                     /protein_id="HGS1785933.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILEGLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYIPGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            1738..8568
                     /locus_tag="ACL8JK_001035"
     CDS             1738..8568
                     /locus_tag="ACL8JK_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGS1785934.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAASVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTEEV
                     TKPAEKVEEAKDKKEEVTHQDAVDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADATEAELSAAESSIQSFIIGLELRSNSNKETVSETPVAKKADAVESKEGAK
                     PAATTERSAVDSAILPTSTADKVETTSAPASINEILKLGLSLSDARQNPAIRKEDVNR
                     GYSGFRAASNPANPIVSGSGNTVAFADISQGGRSYSFRGYGNSRGGNSIHYDVTTVRS
                     GNSVNFTISYSAPGDSREFVNNNFILDKGDGFGNPSNATITSSNPIVREQSKSISQGA
                     NYVSHSGYSMTSAISTNTEQTIRFSLPIINLNGDLSVRLKPVTFNVDQGGGGAATSND
                     PYSNSNYYYRANPLYLDANPYGGTNNKTVSEDIDFQTVDLPTSKLPEGQTRLVREGEK
                     GQRQITYKVHRFGNETLLGLPISNSVTKEAKPRIMQIGVAKDLIDTVKPRVDQNKVGD
                     TNNLTFYLDNDGNGVYTEGVDELVQKIAIKDGAKGEKGAQGERGLTGAKGEKGDRGER
                     GLTGAQGAKGEKGAQGERGLTGAQGAKGEKGDQGERGLTGAQGAKGEKGAQGERGLTG
                     TQGAKGEKGDRGERGLTGTQGAKGEKGDRGERGLTGAQGAKGEKGARGERGLTGAQGE
                     KGDRGERGLTGAKGEKGAQGQAGRDGVTPTVTVKDNKNDGTHTITINDGRGNVTSTVV
                     RDGFDGASPLVATQRNDADKTTTVIFYYDKNGNNELDASDKKLKEVVIADGAKGEKGD
                     KGEQGLQGRDGEQGPKGEDGKTPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFDGA
                     SPLVSTHRNEADKTTTVIFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNGKD
                     GFTPEVTVTDNNNGTHTITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTTLT
                     FYIDKDGDGSYTAGKDELVQTTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDGDT
                     FVNTQTGDVFVKKGNTWEPAGNIKGPKGDKGADGAKGEKGAQGERGLTGAQGVKGEKG
                     DQGERGLTGSKGEKGAQGERGLTGAQGAKGDKGEQGLQGRDGAQGPKGADGQRGPAGP
                     QGPKGEQGNPGTPGKDGKSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNG
                     TNGQSPTITATRSVQNGKNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQN
                     GTHTLTVHNPGSPDVTTTIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETG
                     DVYVKNNGNWDKEGNIKGPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGR
                     DGKDVLNGKANPEAHQGKDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGED
                     GKTPEVTVTPGKDGHSTDITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGN
                     PSHTIVTFYTDENNDGKYTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVY
                     QEDPANPGQPLNPEKPLAVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTT
                     VFVQDGAKGETGATGQDGQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKD
                     GRAPKIKVEDITSPSRIRRDTDAAATPTRNGIRVTVYDDVNDNGVYDEGVDKVLNSKD
                     IYNGIDGRDGSAPTITTKDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENP
                     DGSHTITVTNPDGSTKETVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIK
                     DGKDGKAATATTTENPDGSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDG
                     SHTIVITNPEGVTTETTVRDGKSPKVTITDEQNGTHKISVLNGDGTTTTTTVRDGREP
                     KLEVIDNNDGSHTIKVTGADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREY
                     KSIIKDGKDGKDSVSPTVTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVE
                     DNGDGSHTITIINSDGTVTKTVIKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSND
                     KPVPPTPNVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVAPTTGKENRGDKLPE
                     TGSQSDYISVLLGSGILLSLYVGRRKEA"
     gene            complement(8805..9353)
                     /locus_tag="ACL8JK_001036"
     CDS             complement(8805..9353)
                     /locus_tag="ACL8JK_001036"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGS1785935.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            9674..10162
                     /locus_tag="ACL8JK_001037"
     CDS             9674..10162
                     /locus_tag="ACL8JK_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGS1785936.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            10159..11346
                     /locus_tag="ACL8JK_001038"
     CDS             10159..11346
                     /locus_tag="ACL8JK_001038"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS1785937.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            11339..11704
                     /locus_tag="ACL8JK_001039"
     CDS             11339..11704
                     /locus_tag="ACL8JK_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS1785938.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            11720..13066
                     /gene="asnS"
                     /locus_tag="ACL8JK_001040"
     CDS             11720..13066
                     /gene="asnS"
                     /locus_tag="ACL8JK_001040"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGS1785939.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            13219..13509
                     /gene="rpsF"
                     /locus_tag="ACL8JK_001041"
     CDS             13219..13509
                     /gene="rpsF"
                     /locus_tag="ACL8JK_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGS1785940.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            13521..13991
                     /gene="ssbA"
                     /locus_tag="ACL8JK_001042"
     CDS             13521..13991
                     /gene="ssbA"
                     /locus_tag="ACL8JK_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HGS1785941.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            14023..14262
                     /gene="rpsR"
                     /locus_tag="ACL8JK_001043"
     CDS             14023..14262
                     /gene="rpsR"
                     /locus_tag="ACL8JK_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGS1785942.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            14557..15957
                     /locus_tag="ACL8JK_001044"
     CDS             14557..15957
                     /locus_tag="ACL8JK_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HGS1785943.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFAALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVYLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            15959..16318
                     /locus_tag="ACL8JK_001045"
     CDS             15959..16318
                     /locus_tag="ACL8JK_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HGS1785944.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            16372..17121
                     /locus_tag="ACL8JK_001046"
     CDS             16372..17121
                     /locus_tag="ACL8JK_001046"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGS1785945.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPHSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            17111..17410
                     /locus_tag="ACL8JK_001047"
     CDS             17111..17410
                     /locus_tag="ACL8JK_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGS1785946.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            17481..18416
                     /locus_tag="ACL8JK_001048"
     CDS             17481..18416
                     /locus_tag="ACL8JK_001048"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGS1785947.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            18503..19015
                     /locus_tag="ACL8JK_001049"
     CDS             18503..19015
                     /locus_tag="ACL8JK_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="HGS1785948.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            18999..19647
                     /locus_tag="ACL8JK_001050"
                     /pseudo
     CDS             18999..19647
                     /locus_tag="ACL8JK_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614493.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            19748..19942
                     /locus_tag="ACL8JK_001051"
     CDS             19748..19942
                     /locus_tag="ACL8JK_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGS1785949.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(19988..21433)
                     /locus_tag="ACL8JK_001052"
     CDS             complement(19988..21433)
                     /locus_tag="ACL8JK_001052"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGS1785950.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGTTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            21539..23161
                     /locus_tag="ACL8JK_001053"
     CDS             21539..23161
                     /locus_tag="ACL8JK_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGS1785951.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLAMGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKVQADRLRAKFKLS"
     gene            23366..25324
                     /locus_tag="ACL8JK_001054"
     CDS             23366..25324
                     /locus_tag="ACL8JK_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1785952.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRATTNDIVTNLVDGLMENDQYGNYVPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGI
                     KALDDQTVQYTLARPEPYWNSKTTSTILFPVNADFLKSKGDDFGKVDPANILYSGPFL
                     MKAFVSKSVIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTKMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            25535..26269
                     /locus_tag="ACL8JK_001055"
                     /pseudo
     CDS             25535..26269
                     /locus_tag="ACL8JK_001055"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            26456..27178
                     /locus_tag="ACL8JK_001056"
     CDS             26456..27178
                     /locus_tag="ACL8JK_001056"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785953.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLEQFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGRSQRLQIARAYLKDAEIL
                     IFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            27336..28430
                     /locus_tag="ACL8JK_001057"
     CDS             27336..28430
                     /locus_tag="ACL8JK_001057"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGS1785954.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            28438..29604
                     /locus_tag="ACL8JK_001058"
     CDS             28438..29604
                     /locus_tag="ACL8JK_001058"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGS1785955.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IHQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            29697..32795
                     /locus_tag="ACL8JK_001059"
     CDS             29697..32795
                     /locus_tag="ACL8JK_001059"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS1785956.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLIFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGPVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVTVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            32843..33460
                     /locus_tag="ACL8JK_001060"
     CDS             32843..33460
                     /locus_tag="ACL8JK_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGS1785957.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTAPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            33471..34805
                     /gene="murC"
                     /locus_tag="ACL8JK_001061"
     CDS             33471..34805
                     /gene="murC"
                     /locus_tag="ACL8JK_001061"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGS1785958.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            34815..35279
                     /locus_tag="ACL8JK_001062"
     CDS             34815..35279
                     /locus_tag="ACL8JK_001062"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1785959.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            35276..35770
                     /locus_tag="ACL8JK_001063"
     CDS             35276..35770
                     /locus_tag="ACL8JK_001063"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1785960.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            35851..37506
                     /gene="mltG"
                     /locus_tag="ACL8JK_001064"
     CDS             35851..37506
                     /gene="mltG"
                     /locus_tag="ACL8JK_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGS1785961.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSTEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            37577..38059
                     /gene="greA"
                     /locus_tag="ACL8JK_001065"
     CDS             37577..38059
                     /gene="greA"
                     /locus_tag="ACL8JK_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGS1785962.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        12114 a         7065 c         8634 g        10672 t
ORIGIN      
        1 gaaaagtcag cacgattatg ctgacttttt tgataactta taaagtattg gacaaatgaa
       61 tctcatttga taaggtgtta agatgattaa ccaaattcat gattgacaga tgatttcggc
      121 aaataaactt cttggtaatc cctggaatat agaaattaga cacgatgata tcgtaatctg
      181 tctgatttaa aatctcagga cttgttttta attcatccca aatatcgaag gtaaagcggt
      241 tattacagta ataggaaagc atatcaacaa aggtaaggga tatagcatgg tcaaagttac
      301 tgataatcaa aaccttgata ggtggtcgat tttctaacaa ctgagtagag aggttttcag
      361 catgggttaa gatggtgtac atcaagtgtt ccaactgttc aggatggtca tgctgtccaa
      421 ttgcctgacg gtattgagcc aattcttgac gcgcacttcc cataaagtct gggaagtaaa
      481 cttcaaattt tttaatcgtc aatgcttttt gttcaaataa gattggggta gaaaagattt
      541 cctgtctttc aaagaaagca gtgttgtgta aatgccaaat cagctcatcg tggttagtaa
      601 aagtaatctt atattgtttt gataggcctt ctaatatttg actaagtaat tggtaagagt
      661 atcttgcttg actgttatct tctaaagagt tgaagaattc ttgaggatct aggaaaatat
      721 cattctgaag aaaagaaata aaaatttgag cgattgtatc tggagtcatt tcaagcccaa
      781 aatgtttaga gaaataagca agtgtctcct ggaaattcgg aatgctcttt aaaagaggat
      841 aatattcttt gtaaaagtgg ttggggaggt caatgaagtg accattttta accctgtgga
      901 tactgatagc tatcatcagt ttgtacattc tataaattga aaatcgcatt ggataatttg
      961 tgattttata gaagaagtca gcaaactctg ttaaatcttc ctcaggaagg tcaggaaaag
     1021 gccaatctag gaaataatag cgctcagaaa agtattgggc aaaaaagtaa cgaatatcga
     1081 tctcatttcc acgtatctcg gatggagtaa aagataattc aatttgaaac tgagatgaaa
     1141 gaacctttgt aatatttctg cccagtcgat agaggttggc actactaaag taaagatttt
     1201 ctattgttcg ataaataggt agcccctcat tgaagaacat atactctagt aattgaaaag
     1261 attgagaatt agcaagaaag tattgataaa tatcttctac actagtgtta acttctaaat
     1321 ctatcatgat tccgttaaca gaagattgga tgttaataga tggaaaggca atacgtaatt
     1381 catttaaatc actttttaag attcgttctg tacatcctaa tttttcggct agttcatgta
     1441 atttcatcca attacgattc tgaattaggg tttccattaa gcgtaattgt ctttgaactt
     1501 ttgtggataa aaggtttctc atacgggtat ttcctccata attcattata tctttttttg
     1561 tctaagtagt ataaaaaaat tagagcaaga aaattgtcgt tagtaatcgg aaaaattaga
     1621 ataatataag tggcttttaa gtgcaaaaac agaatatatt aattgttcag aaaatattga
     1681 ttaatgcctc aaatagttgt acattgtaaa ctataaaata ctatctagga gtttaaaatg
     1741 aaacattcac ataaaaaatc atttgactgg tatagcatgc aacaacgtta ttctattcgt
     1801 aagtattact ttggtgcagc tagtgtcttg ctcggtaccg ctttggtatt aggtgcagca
     1861 gctagtgtcc aaacagtaca agcggaagaa aacaaacaag aaactaccaa tagtatttct
     1921 gttggtaggg gagaagcagc tactaaacca gcagaggttt ctgcgtctaa taaagagaaa
     1981 acctatgcag ctccaactgt agctaatcca gtagaaacga ctccagttaa aactgaagaa
     2041 gttactaaac cagcagaaaa agttgaagaa gcaaaagaca aaaaagagga agtaacgcat
     2101 caagatgccg ttgacaagtc aaaattatta acggctcttt cgcgtgctaa aaaattagaa
     2161 agcaagttat atacagaagc aagtgctgct aacttgcaaa caagtatcca agctggtcaa
     2221 agcttgcttg gaaaagcaga tgcaactgaa gctgaattat cagcagcaga gtcatctatt
     2281 caatcattta ttattggtct agaacttcgt tctaactcta ataaagaaac tgtatcagaa
     2341 acgcctgtag cgaagaaagc tgatgcagtt gaatcaaaag aaggggctaa accagctgca
     2401 acaactgaac gttcagctgt tgatagcgct attttgccaa ctagcacagc tgacaaagta
     2461 gaaacaactt cagctccagc atctattaat gaaatcttga aactaggttt gagcctttct
     2521 gatgctcgcc aaaatccagc tatccgtaag gaagatgtta atagagggta tagtggtttt
     2581 agagcggcta gcaatccagc caacccaatt gtctcaggtt ctggaaatac agttgcattt
     2641 gcagatatta gccaaggtgg tcgtagctat agtttccgtg gctacgggaa ctcacgtggt
     2701 ggaaattcta ttcattacga tgtaacaaca gtacgtagtg gtaatagtgt taactttaca
     2761 attagttatt ctgcgccagg agattctaga gagtttgtta ataataattt tatcttggat
     2821 aaaggggatg gatttggaaa tccttcaaat gcaacgatca caagttcaaa tccaatagta
     2881 agggagcaat caaaatctat tagtcagggt gccaactacg tatctcactc aggatacagt
     2941 atgacctctg ctatttcaac aaatacggaa caaactatca gatttagttt gcctatcatt
     3001 aatctaaatg gtgatttgtc tgttcgtttg aaacctgtta cttttaacgt ggaccaaggt
     3061 ggtggtggtg ccgctactag caatgaccca tacagtaact ctaactatta ttatagagca
     3121 aacccactat acttggatgc aaacccttat ggtggtacta ataataagac tgtttcagaa
     3181 gacattgact tccaaactgt cgatcttcca actagtaagt taccagaagg tcaaactaga
     3241 ttagttcgag aaggtgaaaa aggacaacgt caaattacct ataaagttca tcgatttggt
     3301 aacgaaacac ttttaggatt gccgattagt aatagtgtta ctaaagaagc taagccacgt
     3361 attatgcaaa ttggtgtggc taaagatcta atcgatacag taaaaccacg tgttgatcaa
     3421 aataaagtcg gtgatacaaa taacctcact ttctatcttg ataacgatgg aaacggtgtt
     3481 tatactgaag gtgtagacga acttgttcaa aaaattgcta ttaaagatgg agctaaaggt
     3541 gaaaaaggag cccaaggtga acgcggtcta actggagcta aaggtgaaaa aggagaccga
     3601 ggcgaacgcg gtctaactgg agctcaagga gctaaaggtg aaaaaggagc ccaaggtgaa
     3661 cgcggtctaa ccggagcaca aggtgccaaa ggtgaaaaag gggaccaagg tgaacgcggt
     3721 ctaaccggag cacaaggtgc taaaggtgaa aaaggagccc aaggtgaacg cggtctaact
     3781 ggaactcaag gagctaaagg tgaaaaagga gaccgaggcg aacgcggtct gactggaact
     3841 caaggagcta aaggtgaaaa aggagaccga ggcgaacgcg gtctgactgg agcccaaggt
     3901 gctaaaggtg aaaaaggagc ccgaggcgaa cgcggtctga ctggagccca aggtgaaaaa
     3961 ggagaccgag gcgaacgtgg tttaactgga gctaaaggtg aaaaaggagc ccaaggtcag
     4021 gcaggtcgtg acggtgtaac tccaaccgta accgttaaag ataataaaaa tgacggcact
     4081 catactatca ctattaacga cggtagaggt aatgttacaa gtactgttgt aagagatggt
     4141 ttcgatggcg caagtccatt agttgcgact caacgaaatg acgcagataa gacaacaact
     4201 gttatcttct attacgataa aaatggaaac aatgaattag atgcttctga taagaaatta
     4261 aaagaagttg taattgcaga tggtgctaaa ggtgaaaaag gggacaaagg tgaacaaggt
     4321 cttcaagggc gtgatggtga acaaggacca aaaggagaag atgggaaaac cccaacagtt
     4381 aaagtaactg atggtcaaga tggaacgcat acaattacaa ttaacgatgg taaaggtggt
     4441 ataactacta cagtagtaag agatggattt gatggtgcaa gccctcttgt ttctactcat
     4501 agaaatgaag cagataaaac aacaactgtt attttctatt atgatctaaa tgataataat
     4561 caatttgatg aaggagatac aaaacttaaa gaagttgtta tcgcagatgg aaaacaagga
     4621 ccaaaaggtg acaaaggtga taacggaaaa gatggattca caccagaagt aacagttaca
     4681 gataacaata acggaacaca caccatcaca atcacacaac cagacaacag accatcatta
     4741 acaacaatcg ttaaaaacgg tgaagatgga aaaacaccaa aagtcaaagc agaacgagat
     4801 gatgcgaaga aacaaacaac attaacattc tacattgaca aagatggaga tggaagttac
     4861 acagcaggaa aagacgagtt agttcaaaca acagtagtta aagacggaca agacggagct
     4921 gcaggagcat ctggacgtga tggaaaagaa gtattaaacg gaaaagtaga cccaacaaca
     4981 gaaggtaaag atggagacac attcgtaaat acacaaacag gagatgtatt cgttaagaaa
     5041 ggtaacactt gggaaccagc aggaaacatc aaaggaccga aaggtgacaa aggtgcagat
     5101 ggtgccaagg gtgaaaaagg agcccaagga gaacgcggcc tgactggagc gcaaggtgtc
     5161 aagggtgaaa agggagatca gggtgaacgc ggtctaactg gatctaaagg tgaaaaagga
     5221 gcccaaggtg aacgcggttt aactggagcg caaggtgcca aaggtgacaa aggtgaacaa
     5281 ggtcttcaag gtcgtgatgg agctcaagga ccaaaaggcg cagatggaca aagaggacca
     5341 gcgggaccac aaggaccaaa aggagaacaa ggtaatccag gaactccagg taaagatgga
     5401 aaatctctaa ttgctgttaa aaatggaact gaaacaaaag tctatgtaga ggatccggct
     5461 agaccaggac aaccacttaa tccaaaccaa ccattagcaa ctatcactga tggaagaaac
     5521 ggtactaatg gacaatcacc aacaattaca gcgacacgaa gtgtgcaaaa tggcaaaaat
     5581 ggtgtattag taacaattac accagtagga ggtcgtccac aaacaacatt tgtagaggat
     5641 ggacaaaagg gtgctgatgg gaaaacccca acagtaacaa taactgaggg gcaaaacggc
     5701 acacatacat taacggttca taatccagga agtccagatg tgacaactac gatccgtgat
     5761 ggagctacag gacaagcagg tcgtgatggt aaagatgtat taaacggaaa agtaaatcca
     5821 caaccaaacc aaggtaaaaa tggagataaa tatattaata ccgaaaccgg tgatgtctat
     5881 gttaaaaaca atggaaactg ggataaagaa ggcaacatca aaggccctaa aggggacaaa
     5941 ggtgcagatg gtgctaaagg cgaaaaagga gaccaaggcg aacgcggcct aactggagcg
     6001 caaggagcta aaggtgcgga tggcgcagta ggtcgtgatg gacgtgacgg taaagacgtg
     6061 ttgaacggca aagctaaccc agaagcacat caaggtaaag acggcgataa atacgttaat
     6121 acagaaacag gcgacgtctt cgttaagaat aacggcaact gggataaaga gggcaacatc
     6181 aaaggcccta agggtgacaa aggtgaacgc ggagaagatg gtaagactcc agaagtaact
     6241 gtaactccag gtaaagatgg ccatagtact gacattacat tcactgttcc aggtaaagat
     6301 ccagttacag taaatgttaa ggacggagaa aatggtctga acggtaaaac tccaaaagtt
     6361 gatttacttc gtgtccaagg aaaaaacgga aatccatctc atacaattgt gacattctat
     6421 acagatgaaa acaatgacgg caaatataca ccaggaactg atgaacttct aggttcagaa
     6481 atgattaaag atggtgctaa aggcgcggac ggacgagatg gtaaatcatt gcttactgtc
     6541 aaggatggta aagaaactaa agtttaccaa gaagatccag ctaacccagg acaaccatta
     6601 aatccagaaa aaccacttgc ggtaattaga gatggagtag atggaaaatc acctacagtt
     6661 acagctgttc gtaaagatga agcagggcat aaaggtgtag aaatcactgt tgataaccat
     6721 gatggttcac aaccaactac agtctttgtt caagatggtg ctaagggaga aactggtgca
     6781 accggtcagg atggacaaac tcctacaatc actactcaac gtggacaaga tggccaaagc
     6841 actgttgtaa ctatcacaac atcaggtaaa gatccagtaa ccttcactgt aaaagatggt
     6901 aagaatggta aagatggccg tgcaccgaaa atcaaagtag aagatattac ttcaccttca
     6961 agaattagac gcgatacaga tgctgctgca actccaacgc gtaacggtat ccgtgttaca
     7021 gtttatgatg atgttaatga caatggggta tacgacgaag gtgtcgataa agtattaaat
     7081 agtaaagata tttataacgg tatagatgga cgtgatggtt cagctccaac tattactaca
     7141 aaagataatg gagatggaac tcacactatc acagttcaaa acccagatgg ttctgaatca
     7201 acaacagttg ttaaagatgg taaagacggt aaaactgcga atatcactac aacagaaaac
     7261 ccagatggaa gccacacaat tacggtgaca aatccagatg gttcaactaa agaaactgtt
     7321 gttaaaaacg gtaaagacgg taagactcct aaagttgaag taacggataa caacgatgga
     7381 actcatactg ttaaagttac agatggagac ggcaatgtta ccaacgctat catcaaagat
     7441 ggtaaagacg gtaaagctgc aacagcaaca actactgaaa atccagatgg aagccacaca
     7501 gtaacaatca ctaacccaga cggaactaag aatgagtttg ttgttaagaa tggacgtgac
     7561 ggtgttgacg gacgtactcc aaccgcatct gttcgtgata atggagacgg aagtcataca
     7621 atcgttatta caaatccaga aggtgtgaca actgaaacca cagttcgtga tggtaaatca
     7681 ccaaaagtga ctataactga tgaacaaaat ggaactcata agatctctgt tctaaatggt
     7741 gacggaacaa ctacaacaac tacagttcgt gatggtagag aaccaaaact tgaagttatt
     7801 gataacaacg atggttcaca cactattaaa gtgacaggtg ctgatggtaa aggaacgaca
     7861 actacaatct ttgatggtaa atcaccaaaa gcgaacatcg ttgataacgg agatggaact
     7921 catacattaa caatcgtaga ttctgatggt cgtgaataca aatctattat caaagatggt
     7981 aaagacggca aagatagcgt ttcaccaact gtaactgtta aaaataataa cgatggaact
     8041 cacgttgtta caatcactaa tccagatgga agtaagacag aaatggtgat taaagacggt
     8101 aaagatggta aatcaccaaa agtttctgtt gaagataatg gtgatggtag tcatacaatc
     8161 acaatcatca attctgatgg aactgtgaca aaaacagtta ttaaagatgg tagagatgga
     8221 cgtgatggtc gagacggcaa agacggtaaa gacggtaaag atggaaaatg tggatgccaa
     8281 gacaaaccag taacaccatc aaatgacaaa ccagttcctc caacaccaaa tgtgccgaca
     8341 ccagaagtac cggttaaacc tgtgccagcg gttccagaac aaccagtagt accaacaccg
     8401 gctcaaccag caactccagt aaatgctaac ccagtagcac caactacagg taaagaaaac
     8461 cgtggggaca aattacctga aactggaagc caatctgatt atatctctgt tcttttaggt
     8521 agcggtattc tattgagcct atatgtagga cgaagaaaag aagcttaatc agccaaaagc
     8581 agtcactaat ttctcgaaag aagatgataa gtgatagatc tcgaatgaaa gaatattctt
     8641 agaatgattt tcctatgatg gaaaagactg ctaaaaacct tgagtggtaa cgctcaaggt
     8701 ttttttggat ggctgatgtt tgtctgaaaa tcttgattga gaaataaaaa gccaccctat
     8761 taggtggcta taattgattt agactttcta aaattttcta ttttttactg aatcgcttcg
     8821 accaagtctt gagcttgttt ttcaagtgag tttaggactg tttcttcaag aaccaatttt
     8881 ccgtctgccc aggcagagtc attaacacgt gcagcagtga aatcaccaac gccttgtgta
     8941 cggataaatg gcaagaggtc tttgtagata gcgaaaagtt gatcgtgccc tgcattggct
     9001 acagatgata ctgtgacaaa cttgtcttga agggcagaaa cgccacgtgt atcagacaag
     9061 tcaagggcac gagatagcca gtcaagcaag tttttcactg taccagggat agagaagttg
     9121 tagactggag agaaaatcca gatagcatcc gcaacgagaa ctgcttcacg agcagcagct
     9181 acagctggat gtgttggaac ttccaaatct tggctgaaga gaggaagggc tgaataatca
     9241 aggtagctaa cttccgcttt accagcaagt gctttctcag cttcgagcgc catttggtgg
     9301 ttgaaagaac cttgacgtag tgatccgacg ataaataata cttttttaga catgatgtgt
     9361 ctcctttttc ttaaaatttc gagaactctc tcgttgttat aaaatatatt acaacaaaac
     9421 aaaagaactt gcaagaaatt tgctcagagt ttatttgaaa attgtaaaat ttcggaaact
     9481 ctaatcattt gtgactgaaa aagtaagaac tgtttcactt tcaaaatcgg ttttgtttga
     9541 agggagaaat agaattggtt gctcaaagca cagctttgag gttgcagata aagctgacgt
     9601 ggtttgaaga gattttcgaa gagtattctt atattcactt gtaataaagc ttaatagatg
     9661 gtaaaataga cgagtgaaaa aaagacaaaa caaagcaaaa aataatctac tgtggcagta
     9721 tggtctaggg atgacgattt tgtttgtggt tatcagtggt tcctttctgt atatggtttc
     9781 tcttagcatg aaaccctatc aaacagctaa aagtgaagga gaaaaattag ctcagcagta
     9841 tgcaggatta gagcaggctg atcaggttga tttatacaat ggcttggaat cttattacag
     9901 cgttcttggt cgtaacaaac agcaagaagc gcttgctgtc ctgattggta aagatgacca
     9961 taagatttac gtttatcagc taaatcaggg tgtttcacaa gaaaaagcag aaacggtttc
    10021 taaggaaaag ggagctggcg agattgacaa gataaccttt ggccgttatc aagataagcc
    10081 aatctgggaa gttaagtcag gatctgattt ttatctagta gattttgaaa caggagcatt
    10141 ggtcaacaag gagggcctat gaaactatcc aaccgtgttt tagaaatgga agaaagtgtg
    10201 actttggctg ctggagcccg tgccaaagca ctgaaggctg agggtagaga tattttgtct
    10261 ctaaccttgg gtgagccaga tttcactact cccaaaaata tccaagatgc cgccattgca
    10321 tcgattcgag atgggcgtgc ttctttttat acagtaacct caggtctgcc agagcttaag
    10381 gcggcggtca atagctactt tgagcgcttt tacggctatt ctgtagcgtc aaatcaagtg
    10441 acagtcgctg cgggagccaa atattctctc tataccttct ttatggctgt ggtcaatcca
    10501 ggtgatgaag tcatcatccc aaccccatac tgggttagct atggagatca ggtcaagatg
    10561 gcagaaggcg ttcccgtctt tgtttctgct aaggaagaca atcactttaa ggtgaccgta
    10621 gagcagttag aagcagctcg cactgacaag accaaggttt tggtgctgaa ttcgccatct
    10681 aatcccacag gtatgattta cacccgtgag gaactcttgg caattggaaa ctgggctgta
    10741 gaaaatgata ttctcatcct agcagacgat atctatggcc gcttggttta taatggtcat
    10801 gagttcacac cgatttctag cctatcggaa gcgattcgca agcaaacagt ggtcatcaat
    10861 ggtgtgtcta aaacttatgc catgactggt tggcggattg gttatgccgt tggagaagca
    10921 gacattatcg ctgccatgtc caagattgca ggtcaaacaa cttcgaatcc gtcagcagta
    10981 gcccaatatg cagcagttga ggctctatca ggtgagcaag atactgtaga aagcatgcgt
    11041 caggcctttg aggaacgtct taataccatc tatcccctcc ttgcagaggt accaggattt
    11101 gaagtggtca aaccgcaagg ggccttctat ctcttcccaa atgtcaaaaa ggccatggag
    11161 atgaaaggct acacggatgt gacagacttt acaactgtta tcttagaaga agccgaagtg
    11221 gccttggtaa caggagctgg atttggagca ccagaaaatg tccgcctcag ctatgcgaca
    11281 gacctagaca cgcttaaaga agcagtcgaa cgcttgaaag catttatggg tagtgagaat
    11341 gattgatcat tttgagatta aggtaaagga tttacaaatt tcagaaggat tttataggag
    11401 ttttctcgct cctttggact ataaattggc ttttaagact agttctctaa ttagttttct
    11461 atccccgaac agccctcatc ctggtggtga tttttggctg actcagggaa cacaagatcc
    11521 tgttcatttt gcttttttag cagaaaataa ggaagaagtt caggcttgtt atgaggctgg
    11581 cttagaggca ggtgggcgag acaatggggc tcctggttat cgaagtgagc atccgattta
    11641 ctatgctgct tttatgattg acctggatgg gaacaatata gaggtggttt gccataaaga
    11701 ataaaaaaga aaaggaaaaa taatgacaaa acgtgtaacg attattgacg taaaagacta
    11761 tgttggtcag gaagtgacga ttggcgcttg ggttgccaac aaatcaggaa aaggaaaaat
    11821 cgctttctta caattgcgtg atggaacagc cttctttcaa ggtgtggctt ttaaaccaaa
    11881 ctttgtcgaa aaatttggtg aagaagtggg acttgagaag tttgatgtta tcaaacgctt
    11941 gagccaagaa acgtctgttt atgtgacagg tattgtcaaa gaggacgaac gttctaaatt
    12001 tggctatgag ttggacatca cagacatcga agtgatcggt gaatctcaag actacccaat
    12061 cacaccaaaa gaacacggaa cagacttttt gatggataac cgtcacttgt ggctacgctc
    12121 tcgtaagcaa gtagctgtgt tgcaaatccg taacgctatt atctatgcaa cttatgagtt
    12181 ctttgacaag aacggtttta tgaagtttga cagcccaatt ctttcaggaa atgcggcaga
    12241 agattctaca gaactctttg aaactgacta cttcggaacg ccagcctact tgagccaatc
    12301 aggtcagctt tacctagaag caggggctat ggctcttggt cgtgtctttg actttggtcc
    12361 agttttccgt gctgaaaaat caaaaacacg ccgtcacttg actgagttct ggatgatgga
    12421 tgctgagtac tcatacttga cacatgatga gtcgcttgac ttgcaagaag cttatgtgaa
    12481 agctcttcta caaggcgttc ttgaccgcgc gcctcaagcc ttggaaacct tggaacgtga
    12541 tacagaactc ttgaaacgct acattgcaga gccattcaaa cgtatcactt acgatcaagc
    12601 cattgacctc ttgcaagagc atgaaaatga tgaagatgct gactacgagc atcttgagca
    12661 tggtgatgac tttgggtcac cacacgaaac ttggatttca aaccactttg gtgtgccaac
    12721 atttgtcatg aactatccag cagccatcaa ggccttctac atgaaaccag ttcctggaaa
    12781 tccagagcgc gtgctttgtg cagacttgct tgctccagaa ggctatggag aaattatcgg
    12841 tgggtctatg cgtgaggaag attacgatgc ccttgtcgct aagatggatg aacttggcat
    12901 ggatcgtaca gaatatgaat tctaccttga ccttcgtaaa tacggtacag ttccacacgg
    12961 aggatttggt atcggtatcg aacgtatggt aaccttcgca gcaggaacaa aacatatccg
    13021 tgaagctatt ccattcccac gtatgttgca ccgtatcaaa ccataagaac aggaaaacgc
    13081 ccatgtggcg ttttttcgaa ttctagtgtt tttacttgcg taaaaaaatt ttttctagta
    13141 taatagttta ttgtgagcga acctcactta ccccttgcaa agtcttgggg tcattagacc
    13201 aaaaggagga acatatcaat ggctaaatac gaaattcttt atatcattcg tccaaacatt
    13261 gaagaagaag ctaaaaacgc tttggtagca cgttttgact ctattttgac tgacaacggt
    13321 gcaactgttg ttgaatcaaa aacttgggaa aaacgtcgtc ttgcatacga aatccaagat
    13381 ttccgtgaag gactttacca catcgttaac gttgaagcaa atgacgatgc agctcttaaa
    13441 gagtttgacc gtctttcaaa aatcaacgct gacattcttc gtcacatgat cgtcaaaatt
    13501 gacgcgtaag aaggtaaact atgattaaca atgttgtact tgtagggcgt atgacacgtg
    13561 acgctgagtt gcgttatacc ccatcaaatg tagcagttgc gacttttact cttgcagtaa
    13621 accgtacatt taagagtcaa aatggtgaac gtgaggctga ttttatcaat gtcgttatgt
    13681 ggcgccaaca ggctgaaaat cttgctaact gggctaaaaa aggctcactt atcggggtga
    13741 caggtcgtat ccagactcgt agttacgata accagcaagg acaacgtgtc tacgtgacag
    13801 aggtcgtggc tgagaatttc caaatgttgg aaagccgtag tgtgcgtgag ggtcacacag
    13861 gtggagctta ctctgcacca actgcaaact attcagcacc tacaaattca gtaccagact
    13921 tttcacgtaa tgaaaatcca tttggagcaa caaacccatt ggatatttca gatgatgatt
    13981 taccattcta atggacaact aaacttataa aggagaaaaa acatggctca acaacgtcgt
    14041 ggcggattca aacgccgtaa aaaagttgat tacatcgcag caaacaaaat tgaatatgtt
    14101 gattacaaag atactgagct tcttagccgt ttcgtttcag aacgtgggaa aatccttcct
    14161 cgtcgtgtaa caggaacttc agctaaaaac caacgtaaag taacaacagc tatcaaacgc
    14221 gctcgcgtaa tggctttgat gcctttcgta aacgaagatt aaagaaaaga cccagttggg
    14281 tctctttttc atgagcttga aaacaagaaa gcgaattaag accccaacgg gtcttttttc
    14341 acaagctttg aaatgagaga gcgagttagg ctcagtggct ccctttttac gagtttgaaa
    14401 acaagagaac acattaaaag cacgatggag ctttttcata aatatgtctc ttttctcatc
    14461 caagaaatta aaataaaaat gataaacttt ttgaaaatag gggatttgcc tactttatga
    14521 tataatggaa agagttagat tgaaagaggt agtgagatgg acgcgaaatt aagatacaag
    14581 gcaaagaaga tcaagattgt cttttttgat attgatgata cattgcggaa ttcaaagaca
    14641 gggtttattc caactacaat tcccactgtt tttaaacagt tgcgtgaaaa aggaatttta
    14701 acaggaatcg cctctggacg tggcattttt ggtgttgttc cagagattcg tgatctcaag
    14761 cctgactttt ttgtaacttt gaatggggct tatatcgaag ataaaaaagg tcaggtcatt
    14821 tatcagcatc agattgaaaa gtcagatgtt gaggagtata tctcttgggc taagcaagaa
    14881 ggaattgagt atggcttggt tgggagtcat gatgccaagt tgtcgactcg caccgatatg
    14941 atgagtgaag ctatcaatcc aatttatccc gacttagatg tagatcccga tttccatgaa
    15001 aaagaagata tctatcagat gtggactttt gaagataagg gagatgactt gcacttgcct
    15061 gacagtctct cagacaaact tcgcatggtt cgttggcatc aacattcgtc tgatattgtg
    15121 ccgatttcag gctccaaagc gacgggggtg gaaaaggttg tggaacacct tggcttgaaa
    15181 ccagagaagg tcatggtttt tggagatggt ctcaacgact tggaactctt tgattatgct
    15241 ggaatcagcg ttgccatggg aatttctcat gataaaatca aagaaaaagc agattatatt
    15301 acaaaaacat tagaagaaga tggcattttt gctgccttag aagtatttgg tatggtagaa
    15361 aaagaattgc attttccaca agtagacatt gaaacagtag aaggtcctct tgcgactatt
    15421 aagaccaatc acggagactt acgtatcaag cttttccctg aacatgctcc taaaacagtg
    15481 gctaactttg tatatctttc aaaagatggc tactatgatg gtgtcatttt ccaccgtatt
    15541 atcaaggact ttatgatcca aggtggagac ccaactggaa ctggtatggg tggcgagtca
    15601 atctacggcg aatcttttga ggatgaattc tcagaagagc tttacaatat ccgtggtgct
    15661 ctttccatgg caaatgctgg tccaaatacc aacggcagcc agttctttat cgtgcaaaac
    15721 caacacctac cttattctaa gaaagaaatt actcgtggtg gttggccaga accgattgca
    15781 gaaatctatg ccaatcaagg tgggacacct cacctagacc gccgtcacac ggtttttggt
    15841 cagttagctg atgaagcatc ttacgctgtc ttggatgcca ttgctgctgt tgagacagga
    15901 gctatggaca agccagttga agatgttgta attgaaacta ttgaaatcga ggactaagat
    15961 gaaaatcggt gataagctaa aggggcgtat tacagggatt cagccctacg gtgcctttgt
    16021 tgagttagag acgggtgata cggggctgat tcacatttca gagattcgga caggatttat
    16081 tgaaaatatt catgaaacct tgaaagtcga tgaagaggtt caagttcagg tagtggattt
    16141 agatgaattt acagggaaag ccagtctttc tatccgcact ttggaggaag aaaagtacca
    16201 gtttcctaga cggagacgct tttcaagcga ccgctttaac tacggctttg ctccctttcg
    16261 acgaatgcta ccaatctgga ctggagaagc cctgcaccat ttaaaaaaga agaagtagtt
    16321 tagagtttta tattttttgt aatgttaata taaatttgct ataataggac catggaagaa
    16381 gaacaattat taaaatcagg agagcgcatt aaccagctct tttcgacaga tatcaaaatc
    16441 attcaaaata gagaggtttt tagttattcg gtggatagtg ttctcttatc acgatttcca
    16501 cgttttccta agaaggggtt gattgtggat ttttgtgctg ggaatggagc agtggggctt
    16561 tttgctagca ctcgtactca agcacagata ttgtctgttg agattcagga gcgtttggcg
    16621 gatatggctg aacgctctgt ccgtttgaat ggattagagg aacaaatgca ggtcatctgc
    16681 gatgatttga aaaatatgcc tgctcacatt caggggagta aggtggatat gattttgtgt
    16741 aatccaccct atttcaaggt ggatcctcat tctaatctga acgagagtga acattatctc
    16801 ttggctcgac acgaaatcac gactaatttg gaagaaatct gtcatagtgc ccagagtatt
    16861 ctcaagtcta atgggcgttt ggccatggtt catcgtcctg atcgacttct ggatattttg
    16921 gatacgttaa aacgacataa tctagcccct aagcgcctgc agtttgttta tccaaaaaga
    16981 gaaaaggaag ccaatatgct tttgattgag gcgatcaagg atggctcaac aagtggcttt
    17041 aaggtcttac ctcctttgat tgtccacaat gatgatggct cttatacgcc cgaaatcgaa
    17101 gagatttatt atggatcata aggcttatat gtacgttctg gagtgtcgtg atggatccta
    17161 ctatataggc tatacgactg atgtgagaag acgcctcgct atccacaata gtgggaaggg
    17221 agccaaatat acacgagcac gcttgccagt caaacttatc tatgctcaag gttttgccag
    17281 taaggaagaa gccatgtcgg ctgaagctct tctcaagcgt aagaagaggc cacagaagga
    17341 agaattttta tctgaaaatc aagatagaaa tttactcagt tattttgaag aatcgtgggg
    17401 agtcctttga ctcctcttac ctttgtcaaa aagcgaaaaa aatgctacaa taaagaaaat
    17461 aaacaaaatg aggtattatc atgtccaaga ttctagtatt tggtcaccaa aatccagact
    17521 cagatgccat cggatcatct gtagcttttg cctaccttgc aaaagaagct tacggtttgg
    17581 atacggaagc tgttgccctt ggaactccaa atgaagaaac agcctttgtc ttgaactatt
    17641 ttggtgtgga agcaccacgt gttatcactt ctgccaaagc agagggggca gagcaagtta
    17701 tcttgactga ccacaatgaa ttccaacaat ctgtatcaga tatcgctgaa gtagaagttt
    17761 acggtgttgt agaccaccac cgtgtggcta actttgaaac tgcaagccca ctttacatgc
    17821 gtttggagcc agttggatca gcgtcttcaa tcgtttaccg tatgttcaaa gaacatggtg
    17881 tagctgtgcc taaagagatt gcaggtttga tgctttcagg tttgatttca gatacccttc
    17941 ttttgaaatc accaacaaca cacccaacag ataaaatcat tgctcctgaa ttggctgaat
    18001 tggctggtgt gaacttggaa gaatatggtt tggcaatgtt gaaagctggt accaacttgg
    18061 ctagcaaatc tgctgaagaa ttgattgaca tcgatgctaa gacttttgaa ctcaacggaa
    18121 ataatgtccg tgttgcccaa gtgaacacag ttgacatcgc tgaagttttg gaacgccaag
    18181 cagaaattga agctgcaatg caagctgcca acgaatcaaa cggctactct gactttgtct
    18241 tgatgattac agatatcgtc aactcaaact cagaaatatt ggctcttggt gccaatatgg
    18301 acaaggtcga agcggctttc aatttcaaac ttgaaaacaa tcatgccttc cttgctggtg
    18361 ccgtttcacg taagaaacaa gtggtacctc aattaactga aagctttaat gcgtaagatt
    18421 ttgggtgtca gctcaaaatc ggaaagtcta gtttgcctta tatcgaaagg agtttcggct
    18481 cctttttttc taggagtgaa gtatgttaga aaatggcgat ttgatttttg tgagagatgg
    18541 gtcagacatg ggacaggcca tccagacttc cacaggtaac tatagccatg ttgccattta
    18601 tttggatggg atgatttatc atgctagtgg acaggctggt gttgtctgtc aagaaccggc
    18661 agacttcttt gagtccaatc atttgtacga cctctatgtt tacccagaaa tggatatcca
    18721 gtcggtgaag gaaagagctt gcagacatct tggagcaccc tacaatgctt ctttctatcc
    18781 agatgcagct ggtttctact gctcccagta tatagcagaa atcctaccta tttttgaaac
    18841 tattcctatg aaatttggag atggggaaca ggagattagt gatttttgga gggagtatta
    18901 catagaacta ggtctgcctg ttcctctgaa ccaagctggg accaatccta gtcagttggc
    18961 agcatcgcct ctgttacaat gtaaagaaag gaatcttcat gattcagatt tttaatccat
    19021 ctcgtttgac gagacagcca tttttggaga attgatccgc tatctggacc agtatgagga
    19081 tgtgattcta cgggaaatta aggctcaatt tccagatgtt gcagttgata aactcatgga
    19141 agagtatata aaggcaagct tgattctacg tgaaaataag cgctattacc tcaattttcc
    19201 tacgcttgaa tcacttgata gtcttgaact ggatcaagag atttttgtca gagaagctag
    19261 tccggtctat caagccttgt tggagtagag ttttgagacg gaattgcgca atcaaatcaa
    19321 tgcagctatt ttagttgaaa gacggacttt gcgcgcatta aaatgaccct gtccaattat
    19381 ttttacaagg tcaaacagca gtatcctttg acagaaaaac agcaggagct ctatgacatt
    19441 ttaggagatg ttaatcctga gtatgcactc aagtatatga cggctttttt gttgaaattt
    19501 ctcaaaaaag accagcttat gcagaaatgc cgtgatatct ttgtggacag tttggttgtc
    19561 ttaggctata ttgtgcaaaa tgaagataga aagtatgagt tggctatcga ttttgataag
    19621 gagagattaa ctttctactt agcgtgattt cttgtttctg agcacattgt ttgactttcc
    19681 ttagtattcg gtataaacta tatgtaaccg gtaacacata tcggaataaa ctaaaggaga
    19741 caatcatatg tcacttgaaa acaaattgga acaagcaaca ggcgctgtca aagaaggttt
    19801 tggtaaagtt actggagaca gcaagacaga acttgaagga gctgttgaaa aaacagttgc
    19861 taaggcaaaa gacgttgtag aagacgcaaa aggtgctgta gaaggtgccg ttgaaggttt
    19921 gaaaaacgtt tttactaaat aataggaaaa aatcaagggt ttcattttcc cttgattttt
    19981 tctattctta taaataattt tctgcgacgg ctgtatctcc tgggtaggat tctttcttgc
    20041 cctggatgat ttggtaacaa tcggctccct tacccgcaat aataactgca tctaattcgt
    20101 gatttgtgat agccattgcc gccttgatgg cttcttggcg atccgcaatc ttttcaacag
    20161 gatgattgat gtagctacta atttcatctg caatggccat tgggtcttca tagttagggt
    20221 catcagcagt cagaaagact tgaatctcag ggtgttgatt gaggaggagg ccgaagtcct
    20281 tacgacgact ttctcccttg tttcctgttg ttcccagaac cagagcaatc tttccggttt
    20341 gatgagtttc aaccacattg atgagttttt tcagactatc cccattgtgg gcatagtcga
    20401 tgaagacctt ggctccattt ttctgagtga ggacttccat acgaccagga acgcgggttg
    20461 cagcgatgcc ttttttgatg tcctcaagac ttgctccgag acggagacaa gcaagtccag
    20521 cagcaactgc attttcttgg ttgaagttgc caatgagttg gatatcataa tctccagcga
    20581 gtttacccgt agctgaaaag ctaaaggctt tggaattctc gatttggtta tcaaattggc
    20641 taccatagaa atcatggtct tgatcttcaa cctgttcttt caagactgag aagtggtcca
    20701 tgtcactgtt aatgatgact gctcggctat tttccatcaa gagacgcttg tggtagaaat
    20761 agtcttcaaa gctagggtgt tcaatcgggc cgatatggtc aggagtgatg ttaagaaaga
    20821 ctcctacatc aaaggtcagt ccatagactc gatggactag ataggcttga ctggagactt
    20881 ccatgatgag gtgggtacgg tcattttgca cagcctgatt catcatgtca aagaggtcaa
    20941 tactctcagg ggttgtcaac gctgacttaa agaaagtctc gccatcaaga gttgtgttca
    21001 tggtcgacaa catagcaggt ctatgccctt gagataagat gttataggcg aaataggttg
    21061 ctgttgtctt acccttagta ccagtaaagg caaggagttt gagtttctct tgtggattac
    21121 catagaactc catggcaatc aaactcatgg ctttctttat atcgttcaca atgatgacag
    21181 ggataccgac ttcgtagtcc ttttcagcta cataccaagc taaaccttgt gttatagcag
    21241 aaagaaggta ttctttttta aaggcagcgc cttttgcaaa aaaaagagtg tcttctgtta
    21301 cttttcggct gtcgtagctg atgctatcaa aaataacttt gctgtagttg tagtggtaat
    21361 gaccttggtc aataatttcg cgaaaaaggc catctttctt taaaatatct aatacggttt
    21421 caatcttaat catactttct attgtaaacc gaaagtcgta aatttacaag taacaaggaa
    21481 aagtttataa tggaagataa ggagtttttc ctagttatca aaattgaatg aggaatctat
    21541 gtcgcacgaa aacaatcacc agcaggccca gatgttacgg gggactgctt ggctaacggc
    21601 tagtaacttt atcagtcgcc tactcggggc tgtttacatt atcccttggt acatctggat
    21661 gggggcttat gcagctaagg caaatggtct ctttaccatg ggttacaata tctatgcttg
    21721 gttcttgttg gtttcaacag cggggattcc agttgcggtg gccaagcaag ttgccaagta
    21781 taataccatg cgagaagaag agcatagctt tgccctgatt cggagcttct taggctttat
    21841 gacaggacta ggcctggttt ttgctttagt cttgtatgtc tttgctcctt ggctagcaga
    21901 cttgtctggc gtgggcaaag acttgatccc aatcatgcaa agcttggctt ggggagtctt
    21961 gattttcccg tctatgagtg ttatccgagg atttttccaa gggatgaata acctcaaacc
    22021 ctatgccatg agccaaattg ctgagcaggt cattcgtgtt atctggatgc tcctagcaac
    22081 ctttatcatt atgaagctcg gttcaggaga ttatctagca gccgttaccc aatcaacctt
    22141 tgctgccttt gtcggtatgg tagccagttt tgcagtcttg atttatttcc ttgcccaaga
    22201 aggttcactc aaaagagtct ttgaaacagg agataagatt aacagtaagc gtctcttggt
    22261 tgataccatt aaggaagcca ttccttttat cctgacaggg tctgccatcc agctcttcca
    22321 gattttggat cagctgacct ttatcaatag tatgagctgg tttaccaact acagcaatga
    22381 ggacttggtt gtcatgtttt cttatttctc agccaatcct aataaaatca cgatgatttt
    22441 gatttctgta ggggtttcga ttgggagtgt tggtttgcca cttttgacgg aaaactatgt
    22501 caagggggac ttgaaagcag cttctcgtct ggttcaggac agtctcaccc tactctttat
    22561 gttcttgcta ccagcaacgg ttggagtggt tatggtagga gaacctcttt atacggtctt
    22621 ctatggtaag ccagatagtt tggctatggg cttatttgtc tttgcagttt tgcagtctat
    22681 tattttaggt ttgtacatgg tcttgtctcc aatgcttcag gccatgttcc gcaaccgcaa
    22741 ggccgttctc tattttatct atggttctat tgccaagcta gtcttgcaac tacctaccat
    22801 cgccctcttc cacagttatg gtcctttgat ttcaacaacc attgctctca tcattcctaa
    22861 cgtcttgatg tatcgggata tttgtaaagt aactggtgtc aagcgcaagg tgattttgaa
    22921 gcgaaccatt ttaatcagtt tgctgaccct agtcatgttt ctgttaatag gaaccatcca
    22981 gtggctgtta ggatttttct tccaaccaag tggacgtttg tggagcttct tttatgtagc
    23041 tcttgtcggt gccatggggg gtggacttta tatggttatg agtctgcgta cctatttatt
    23101 agataaggta ataggaaaag tccaagcaga tcgcctgcga gcaaaattta agctttcgta
    23161 aggtggcatt tataaataaa aggaataagt tgaacaatct tttaggagaa cttgaaactt
    23221 attccttttt ttagcgtcaa aatagctaaa attatctttc aaaaatagaa aatgaggttt
    23281 ttttcgattt tttggaaaaa acaattgact aaacaaacaa agagttgtat aataaaacaa
    23341 atatttaaag caggaggttc tggaaatgaa aaagtctaag agcaaatatc taaccttggc
    23401 aggtcttgtc ctgggtacag gagttttatt gagcgcgtgt ggaaattcta gcactgcatc
    23461 aaaaacctat aactatgttt attcaagtga tccatctagt ttgaactatc tagcagaaaa
    23521 ccgcgcaaca accaatgata ttgtgaccaa tctggtagat ggtctcatgg aaaatgacca
    23581 atatgggaac tatgtgccat ccttggcaga agattggact gtttctcagg atggtttgac
    23641 ctatacctac aaacttcgta aggatgccaa gtggtttact tctgagggag aagaatatgc
    23701 acctgtaact gcccaggatt ttgtgacagg attgcaatat gcagctgata aaaaatcaga
    23761 agccttgtat ctagtgcagg actctgttgc aggtttggat gactatatca ctggtaaaac
    23821 aagcgacttt tcaactgtcg gtatcaaggc tcttgatgat caaaccgttc aatacacctt
    23881 ggctcgacca gaaccttact ggaactcaaa aacaacctca accattcttt tcccagtcaa
    23941 tgcagatttc ttgaaatcaa aaggggatga ttttggcaag gtagaccctg ctaatatttt
    24001 gtacagtgga cctttcttga tgaaagcttt tgtttcaaaa tctgtcatcg aatacaagaa
    24061 aaatcctaac tactgggatg ctaaaaatgt ctttgtagac gatgtgaaat tgacctacta
    24121 tgatggtagc gaccaagaat cactggaacg taattttaca gctggtgctt atactacggc
    24181 tcgtcttttt cctaacagct ccagctatga agggattaaa gaaaaataca aaaacaatat
    24241 catctatagt atgcaaaatt caacttcata tttctttaat tttaacctag ataggaagtc
    24301 ttacaattat acttctaaaa caagtgacat tgaaaagaaa tcgactcagg aagcagttct
    24361 caataaaaat ttccgtcagg ctatcaattt tgcttttgac agaacatctt atggggctca
    24421 gtctgaaggg aaagaaggtg caacaaagat tttgcgtaac ctagtggttc ctccaaactt
    24481 tgtcagtatc aagggaaaag actttggtga agttgtagcc tctaagatgg tcaactatgg
    24541 taaggaatgg caaggtatca actttgcgga tggtcaagac ccttactaca atcctgagaa
    24601 agccaaggct aagtttgcgg aagctaagaa agaactcgaa gcaaagggtg ttcaattccc
    24661 aatccacttg gataagactg tggaagtaac agataaagta ggcatacaag gagttagttc
    24721 tatcaaacaa tcaattgaat ctgttttagg ttctgataat gtagtgattg acattcagca
    24781 attaacatca gatgagtttg acagttcagg ctactttgct caaacagctg ctcagaaaga
    24841 ctatgattta tatcatggcg gttggggacc tgattatcaa gacccgtcaa cctatctcga
    24901 tatttttaat actaatagtg gaggagttct acaaaatctt ggactagagc ctggagaagc
    24961 caatgacaag gctaaggcag ttggactgga tgtctatact aaaatgttgg aagaagctaa
    25021 taaagagcaa gatccagcca aacgttatga gaaatatgct gatattcaag cttggttgat
    25081 tgatagttct ttagttcttc caagtgtttc gcgtggggga acaccatcat tgagaagaac
    25141 cgtaccattt gctgctgcct atggtttaac cggtacaaaa ggggttgaat catataaata
    25201 cctcaaagta caagataaga ttgtcacaac agacgaatat gcaaaagcca gagaaaaatg
    25261 gttgaaagaa aaagaagaat ccaataaaaa agcccaagaa gaattggcaa aacatgtcaa
    25321 ataaaatcta attgtagata agtttgtgta agaagtcttt gtgcttaaaa acgcataata
    25381 tcaggtatat aaaatcctag atgttatgcg ttttgttata ggaagattta ttagatttta
    25441 tcctcaaatt gagttattcc cgactttatc cgttgaaata ttataaggag tatttatgaa
    25501 attaaaatta ttaagagtag atactaaggt gattatgggg agtttcttac ttgttctgtc
    25561 tagtctactt gctttgttgc ttccccttat cttaaagggt ttaatagatg ggagttctat
    25621 tgaaaatata ggttccaaag tatttcaatc gtttttgatt tttattggtc aagccttgtt
    25681 ttcttctatt ggttactatc tgtttagtca atcgggtgaa aaaaagatag caaaaatcag
    25741 gaaaaaagtg acagaggggt tgatttatgc agagaaatcc ttctttgata agagccaaag
    25801 tggggagttg acttctgcca ttgtcaatga cacgagtgtc attcgtgagt ttttaattac
    25861 gactttccca aatattattc tgagtttagt tatggtactt ggttccattg tagtcttatt
    25921 tagtcttgat tggaatcttt ctctactttt attcatcact cttccttgta tgatgtttat
    25981 tatcttgccc ctttccaata tcagtgaaaa gtatagtcgt cgtttacagg aggaaatcgg
    26041 atttttaaca gggcaattga ctgaaaagat tcaagaacat gaattaatta agactaacca
    26101 agcagagaaa agtgtacagg atgttttgga taattgtatt gaaagggtac aaaacaattc
    26161 actgaaatca gatagggtta cttcttttga gaccccgttt gctctcttat ttatctttgc
    26221 gactatagct gtgatgctaa cctatggggg ttatcgggtc agcgcaggat atatatctgt
    26281 gggaaccttg gtttcgtttt tgatttacct ctttcaatta cttaatccta ttagtaatat
    26341 agctaatttt gtaactgttt attctaggag caagggatct tcagttgcac tggagaactt
    26401 gcttgcagtt cctaaagaaa aatttgaggg aggaaaatcg gtatcaggac aagggttgaa
    26461 ttttaaccat gtctattttg gttatgatga aaatcgacct gtcttaaagg atattacttg
    26521 ttcaattttc aaggggcaaa aaattgcttt tgttggacca tctggatcag gaaaatcaac
    26581 gattgtgcgt ttgttagagc agttttataa accgctttca ggagatattc taatggagca
    26641 atcaagtata tatgatttta acttaaaaga atggagaagt aaaatcgctt gggtttcaca
    26701 aaataatgca gtcttatctg gcagtattcg tgacaatctt tgtctcggtt tgaatcgctt
    26761 agtaactgat gatgaattga tgaaagtgct agacttagta tcactaggtg atgagattcg
    26821 ctccatgaaa gagggactag atactgaagt tggtgaacgc ggacgactct tgtcaggggg
    26881 gcgaagccaa agacttcaaa tagctagagc ctacttaaaa gatgctgaaa ttcttatatt
    26941 tgatgaagcc actgctaatc ttgatgcgga ttctgagtat gcgattatca gtagcctcta
    27001 ttctgtacta aaggagaaga cggttgtgat tatagcgcat cgtttgtcaa cggtaaaaga
    27061 tgtggattgt attttcttct tagaggaggg gaaaatcact ggctcaggaa ctcataagga
    27121 actactggaa aatcatgagc gttatgctcg ttttgtgcag gagcaaatga tagagtgaag
    27181 gtgtcttttg agattcacca ttttatagtc tattaaaggg agcaggaaaa actccctttt
    27241 tatatagttt gaaactataa ctagctcttg aaaagaagaa aatgagttga tgaaaataag
    27301 tggtacaata gttactatag atttggagga attgtatgag caaggaatta cacattaaca
    27361 caattttagc acaagcaggg atcaagtctg atgaggcaac aggtgctttg gtgacaccac
    27421 ttcatttttc aacgacctat cagcatccag agtttggtcg atctactggg tttgactata
    27481 cgcgcactaa aaatccaact cgtagtaagg ctgaggaagt cttggcggct attgagtcag
    27541 cagactatgc cctagcgact agctcaggga tgtcagctat tgtactggcc tttagcgtct
    27601 ttccagtagg aagtaaggtc ttggcagtgc gtgatcttta cggtggttct tttcgctggt
    27661 ttaaccaagt ggagcaggaa ggtcatttcc attttaccta tgccaataca gaagaagagt
    27721 tgattgccga gttagaaaag gatgtggatg ttctctatat cgaaacccca accaatccct
    27781 tgatgttgga atttgatatc gaaaaactag caaaattggc tcatgctaag ggtgccaaag
    27841 tggtggtgga caataccttc tatagcccta tctaccaacg tccgattgaa gatggagcag
    27901 atatcgttct ccattcagca accaagtatc tagcaggcca caatgatgtc ttggctggag
    27961 tggttgtgac caatagttta gaactatacg agaagctttt ttacaatctt aatacaacag
    28021 gggcagtctt gtctccattt gacagctacc agttgcttcg tggtctcaag accttgtctc
    28081 ttcgtatgga gcgctcaaca gctaacgccc aagaagtggt tgcctttttg aaggattctc
    28141 cagcagttaa ggaagttctc tacactggtc gtggaggcat gatttccttt aaagtagccg
    28201 atgaaacacg cattcctcat attttgaaca gtctcaaggt cttctctttt gcggaaagtt
    28261 tgggtggagt ggaaagtctt attacttatc caacgactca aactcatgct gatattccag
    28321 cagaagtacg ccattcttat ggtttgacag atgacctctt gcgtttgtct attgggattg
    28381 aggatgctag agatttgatt gcagatttgc gccaagcctt agaaggataa gacaaagatg
    28441 ggaaaatatg attttacaag cctgcccaac cgtttagggc accataccta taaatggaaa
    28501 gaaacagaaa cggatagtga agttctacca gcttggatag cggatatgga ctttgtagtc
    28561 ttgcctgaaa tccaccaagc cgtgcaaact tacgcagacc aactggttta tggttatacc
    28621 tatgccagtg aagacttaat taaggaagtt caaaagtggg aagctacaca atacggttac
    28681 aactttgaca aagaggctct tgtctttatc gagggtgtgg taccagccat ctcaacagct
    28741 attcaaacct ttacaaaaga aggcgaggcg gttttaatta acacgcctgt ctacccaccc
    28801 tttgctcgca gtgtcaagtt gaataatcgt agattgatta ctaattcctt agtggaaaag
    28861 gatagtctgt ttgagattga ctttgaccaa cttgaaaagg atttggtgga agaggaggtt
    28921 aaactctatg ttctttgcaa ccctcacaat cctggtggac gtgtttggga aaaagaagtg
    28981 ttggagaaga ttggccaact ctgccaaaaa cacggtgttt tgttagtttc ggatgagatt
    29041 caccaagatt tgaccctctt tggtcacaaa caccagtctt tcaataccat caatcctgcc
    29101 ttcaaaaatt ttgctatcgt cttgagcagt gccactaaaa catttaatat tgctggaaca
    29161 aaaaattcct atgcagtcat tgaaaatcct aagttgagac tggctttcca gaaacgcctg
    29221 ttggccaata atcagcatga aatttcaggc ttgggttatt tggcgacaga agctgcctat
    29281 cgatacggta aagattggct agaggaactc aagcaagtct ttgaagacca catcaattat
    29341 gtggtggatc tatttggaaa agagactaaa atcaaggtca tgaaaccgca aggtacctac
    29401 ttgatttggc ttgacttttc agcttatgac ctgactgatg aaacattgca agagttgttg
    29461 agaaatgaag ccaaggttat cctcaaccgt ggtttggatt ttggagagga aggaagtctc
    29521 catgcccgca tcaatatagc tatgcccaaa tctctgttgc aagaagtctg tcagcggatt
    29581 gtggctactt ttgccaaatg ttaaaaatcc agccttctag gagaaaagtc ttcctagaag
    29641 gctattttca taggcgaaaa tatggtataa taaaaagata aggtaaaggt gaaaatatgg
    29701 ctaaattgat tccggggaaa attcgtatcg aaggtgttgc cctttatgaa actggtaagg
    29761 ttgatatcat caaggaaaag aacaatcggc tctacgctcg cgttgcagaa gaagaactgc
    29821 gctatagttt agaggatgat ttgatttttt gtgcctgtga tttttttcaa aagaggggct
    29881 actgtgtgca tttggcagcg ctagagcatt ttctgaaaaa tgatgagcgt ggtcaggaaa
    29941 tcttgtggag tctggaagaa ggtcatgaag aaaaagaggc cgttgaaacc aaggtgacct
    30001 tgggtggcaa gtttttggat cgaattttat ctccaaaatc agaatgcgcc tatgagttat
    30061 cagctgtggg tcaggtggaa gcaggaacca atcatatctt gtggactctg agaatcggcc
    30121 aaatcaatag ccaaaaatac tatgtcattc gggatattcc acttttttta aggattgtcg
    30181 agcagagaaa gtcgtatatg attggcaaga tttatgagga gtctctttct tgggaagcct
    30241 ttgatgatgc cagccaagaa cttttgactt tcttgcacgg actaacggag gaagggctgg
    30301 ttccagacct ctttttccaa aaccaaggtc ggcacctctt tttccctctg accttttttg
    30361 agcagggtgt gaatttactg atggccttgc cccattttca atttgaccat caagtggata
    30421 gctaccaaac cctgcttttt caggatatgc atgctgatgc caatctattt gcctttacag
    30481 taacagaata ttcggactat tttgaaatgg aaatcagtga gagtcctagg gtcaatgtct
    30541 tttatcaagg agcagtactt ttccataaag gtcaggttta ttttttaaca gaccagcaga
    30601 tgcgtcttct caaggaaatt aaagcgttac ctgtgggtca acaaggaaag aaatacctgc
    30661 aatttgatag cagtgatcga gacaaattgg cctcctgtct gactcttttt atccagatgg
    30721 gccccgtttc agctccagaa cgtctacaaa tcaaaacttt tgcgccctct ttttactttg
    30781 acagggaaga agataatcgg attcgtttag aaattcagtt tgattatgga aatagacagg
    30841 tatctagccg acaagagcta gaagaattac cattttcaag tgacgcggac ttagaagaaa
    30901 gaattttcca agtctgtttg gctgcgggct ttgaagccga ttttcaatct tggcgtcagg
    30961 ccttaaaagc ggagtctgtc tatcattttt ttcatgatat cattccagtc tttgaaaaac
    31021 tcgggcatgt tgacctatca gataaactag aagagcttta tagcctagcg agtcctcagg
    31081 tgcaaattgc ctccaaggga ggtctcttgg aaatccagtt tgattttcaa gatattgccc
    31141 aggaggaaat cgaccaagcc atgcaggcct tggttgccaa tcaggatttt tatattgatt
    31201 cgtctaatca agtttacttt ttcgatgaag aaaccaagaa aattcgccaa aatctacagg
    31261 aactggggca atttgaatta aaagatggga ccttgcaggc tcggaaatcc ttggcctaca
    31321 gtttagctca tctctttgaa gggcgagacc gtgtttcttt ttcacaagaa ttccagaatc
    31381 tggcccagga tttgacgcat ccagaggact ttcctttgca agcaactcag gtcaaggctg
    31441 acttgcgaga ttatcaggaa aagggaattg gctggttgca gatgctccat cattatggtt
    31501 ttggtgggat tttggctgat gatatgggac ttgggaaaac ccttcagacc attgcttttt
    31561 tgactagtca agtgacaaaa gaaagtcggg ttttgattct cgctccgtcg ggtttgattt
    31621 acaactgggc agatgagttt cagaaatttg ctccacagtt ggatgtgact gttgttcatg
    31681 gtttgaaagc aagtcgtgag gagattcttg ccgagagcca tcaaatctat gtgactagct
    31741 atgccacctt ccgtcaggac agtgagtttt atcaagggat ggcctttgac ttccttttct
    31801 tagatgaggc tcaggtcatg aaaaatgccc agaccaagat tgcccagacc ttgagacaat
    31861 ttgtggtgcc gtcggtcttt gccttgtcag gaactccgat tgaaaaccat ctgggtgagt
    31921 tgtggtctat tttccaaatc gtcatgcccg gacttttgcc aagcaagaaa gaatttatga
    31981 aattgccagc agagcgagtg gctcagttta tcaagccttt cgtgatgcga cgcaagaaag
    32041 aagaagttct gactgaattg ccagacttga ttgaggtggt ttataaaaat gaactggaag
    32101 accagcaaaa ggctatttac cttgcccagt tacaacagat gcgagaccat ctggctcaag
    32161 tgtcagaaca ggaatttcag cgaagtcgtg tggaaatttt atctggtttg atgcgcttgc
    32221 gtcaaatatg tgacactcct gccctgttta tggaagatta tcagggagcc agcggcaaac
    32281 tagatagtct ccgagaccta ttggtacagg tggcagacgg cggacaccgt gtcttgattt
    32341 tctctcagtt caagggaatg ttggaaaaaa ttgaacaaga actgccagac ttgggcctga
    32401 cttcctttaa aattacgggt tcaaccccag ccaaggaaag acaagacatg accaaggcct
    32461 ttaaccaagg agaaagagat gcctttctga tttccctcaa ggctggtggg gtcggtctga
    32521 acctgacagg tgcagataca gtgatcttgg ttgacctttg gtggaatcct gcggtggaag
    32581 cgcaagccat tggccgtgcc catcggatgg gtcaggaaga aacggttgag gtctatcgct
    32641 tggtgaccaa gggaaccatt gaagaaaaaa ttcaggaact ccaagaacaa aagaaacatc
    32701 tggtgtcaca agtattggac ggcacagagt cacgtggtag tctgacccta gcagaaatta
    32761 gagaaatttt gggaatttct gaagccagca cttgaaaaat caagacaata cgctataatg
    32821 aagtgttgaa aggaaataga aaatgaaaca agaacgattt ccattggtgt cagatgacga
    32881 ggtcatgttg actgaaatgc cagtcatgaa tctctatgat gagtctgatc tgatcagtaa
    32941 tatcaagggt gagtatcgag ataaaaatta tttagaatgg gctcctattg ctgaagaaaa
    33001 accagtaaaa ccgattgaaa agcaagtcga aaaacctaaa aaggctcctt taggggttaa
    33061 aaaagaagga aagagctatg cggaggtggc gcgtgaagaa gcgcgtgcgg acttgaaaaa
    33121 gaaacgctct gctaactacc taactcagga tttcagcctt gcgagacgtc attctcagcc
    33181 cagtctagtt agacagggca atcaaccgac agctcctttc caaaaggaaa atcctggtga
    33241 atttgtcaaa tatagccaaa aattgaccca gtctcattat atcttggcgg aagaagttca
    33301 ttctatccct accaagaatg aagaagtgtc agcacctgct ccaaagaaaa acaattatga
    33361 ttttctaaag aagagccaaa tctacaataa aaaaagtaaa caaacagaac aagaacgtcg
    33421 ggttgcccaa gagttgaatc tgaccagaat gacagaatag gggagaaaac atgtcaaaga
    33481 catatcattt tatcggaatt aagggatcag ggatgagtgc cttggccttg atgttgcacc
    33541 agatggggca caaggttcag ggatcagatg ttgaaaagta ctactttacc caacgcggtc
    33601 ttgagcaggc aggaattacc attcttcctt ttgatgaaaa aaatctagac ggtgatatgg
    33661 aaattatcgc tggaaatgcc tttcgtccag ataacaacgt cgaaattgcc tatgcggacc
    33721 aaaatggtat cagctacaaa cgttaccatg agtttctagg tagctttatg cgtgactttg
    33781 ttagcatggg agtagcagga gcacatggaa aaacttcaac gacaggtatg ttgtctcatg
    33841 tcttgtctca cattacagat accagcttct tgattggaga tgggacaggt cgtggttcgg
    33901 ccaatgccaa atattttgtc tttgaatctg acgaatatga gcgtcacttc atgccttacc
    33961 acccagaata ctctattatc accaacattg actttgacca tccagattat ttcacaagtc
    34021 tcgaggatgt ttttaatgcc tttaacgact atgccaaaca aatcaccaag ggtctttttg
    34081 tctatggtga agatgctgaa ttgcgtaaga ttacgtctga tgcaccaatt tattattatg
    34141 gttttgaagc tgaaggcaat gactttgtag ctagtgatct tcttcgttca ataactggtt
    34201 caaccttcac cgttcatttc cgtggacaaa acttggggca attccacatt ccaacctttg
    34261 gtcgtcacaa tatcatgaat gcgacagccg ttattggtct tctttacaca gcaggatttg
    34321 atttgaactt ggtgcgtgag cacttgaaaa catttgccgg tgttaaacgt cgtttcactg
    34381 agaaaattgt caatgataca gtgattatcg atgactttgc ccaccatcca acagaaatta
    34441 ttgcgacctt ggatgcggct cgtcagaaat acccaagcaa ggaaattgta gcagtctttc
    34501 aaccgcatac ctttacaaga accattgcct tgttggacga ctttgcccat gctttaaacc
    34561 aagcagatgc tgtttatcta gcgcaaattt atggctcggc tcgtgaagta gatcatggtg
    34621 acgttaaggt agaagaccta gccaacaaaa tcaacaaaaa acaccaagtg attactgttg
    34681 aaaatgtttc tccactccta gaccatgaca atgctgttta cgtctttatg ggagcaggag
    34741 acatccaaac ctatgaatac tcatttgagc gtctcttgtc taacttgaca agcaatgttc
    34801 aataggatgt tcccatggaa attccaatta agatcattca ggcaagcaag tctgatttgc
    34861 ctgagatagg ggcacttcag acctcgtctt ttccagctga aaagcagcaa ctttcccata
    34921 ttttagaaga aagtatccgt aagtgtgcgg atacctttct tctagctagg gatgaaaatc
    34981 aacttttagg ctatatttta tcaagtcccc agtcagacaa tccgcaatgt ctaaaagtac
    35041 attctttagt catcgagtct gaccatcaga gacagggcct gggaacactt cttcttgcag
    35101 ccttgaaaga ggtggcagtt gagctggatt acaaagggat tcgtttggag agtcctgatg
    35161 agctgctttc ctattttgaa atgaacggtt ttgttgatga agaagcaact ttgctctatg
    35221 caactagcca gggctatagt atgatttggt ttaatccctt ttatctggag gaacaatgaa
    35281 aatcagacaa gcaagattag aagatttgga tcggattgtt gaacttgaat ttgaaaattt
    35341 ttcggtcgaa gaagccattc ctccttctgt ctttgaagca catttgagag aaattcagac
    35401 ctcttttctg gttgctgaaa aagaaggaag aatcatgggt tatatcgaag gaccagttgg
    35461 cctgcaccgc catctgcaag accagtcttt tacagaagaa ataaaagact atagtcatga
    35521 gcctggtggt tatatctctg tgacctgtct gtctattgcc aaggaggcac agggactcgg
    35581 actgggtcag aaattgctga cagccttgaa agaagttgct cttgaagatg agagagatgg
    35641 cattaatcta acctgtcatg actatctcat cgcctactat gaaaaacatg gatttgtcaa
    35701 cgaaggccag tcccagtcaa cctttgcagg ggaaacatgg tatgatatgg tctgggaaat
    35761 gaaaaaataa gttaggaaaa gtatcataga ttgctttttt tggactttta agatataata
    35821 ttatggatta tcaacaagga ggaaaaactt ttgagtgaaa agtcaagaga agaagagaaa
    35881 ttaagcttta aagagcagat tctgagagat ttagaaaaag taaaaggcta tgatgaagtt
    35941 ctgaaagaag atgaggcagt agttcgcact cctgcaaatg aaccttcaac tgaagaactc
    36001 atggctgatt ccttgtcaac ggtagaggag attatgagaa aagctcctac cgtgcctact
    36061 cacccaagtc aaggtgtacc agcttctcca gcagatgaga ttcaaagaga aactcctggt
    36121 gttccaagtc atccaagtca agatgtacct tcttctccag cggaagaaag tggatcaaga
    36181 ccaggtccag gtcctgttag acctaagaaa cttgaaagag aatacaatga aaccccaaca
    36241 agggtagctg tttcctatac gacggcagag aaaaaagcag aacaagcagg tccagaaaca
    36301 cctacgcctg ctacagaaac agtggatatc atcagagata catcacgtcg tagccgtaga
    36361 gaaggagcaa aacccgttaa gcctaagaaa gagaagaagt cacatgtgaa agcttttgtg
    36421 atttcattcc ttgtattcct tgccttgctc tcagcaggtg gttactttgg ttaccagtac
    36481 gtgctagatt ccttattacc tatcgatgct aattctaaga aatatgtgac ggttggaatt
    36541 ccagaaggtt caaacgttca agaaatcggt acgacgcttg aaaaagctgg tttggtaaag
    36601 catggtctga tttttagttt ttatgccaag tataaaaatt ataccgactt gaaagcaggt
    36661 tactacaatt tgcaaaagag tatgagtaca gaagacttac tcaaagagtt gcaaaaaggt
    36721 ggaacagatg aaccgcaaga acctgtactt gcgactttga caattccaga aggttatacc
    36781 ttggatcaga ttgctcaaac tgtgggtcaa ttgcaaggtg acttcaaaga gtctttgaca
    36841 gcggaggctt tcttggctaa agttcaagat gagacgttta tcagtcaagc agtagcgaaa
    36901 tatcctactt tactggaaag tttgcctgta aaagacagcg gtgcgcgtta tcgtttggaa
    36961 ggataccttt tcccagctac atactctatc aaggaaagca caactattga gagcttgatt
    37021 gatgagatgt tagctgctat ggataagaac ctatctcctt actatagtac tatcaaatct
    37081 aaaaacttga ctgtcaatga gttgttgacc attgcttcct tggtcgaaaa agaaggtgcc
    37141 aagacagaag atcgtaagct cattgcaggt gtattttaca atcgtttgaa tcgtgatatg
    37201 ccacttcaaa gtaatattgc aatcttgtat gcccaaggaa aactggggca aaatatcagt
    37261 ctagctgagg atgttgcgat tgataccaac attgattcac cttataatgt ttataaaaat
    37321 gtaggtctca tgcctggtcc agtcgatagt ccaagtctgg atgcgattga gtcaagcatc
    37381 aatcaaacta agagcgataa cctctacttt gtagcagatg tcacagaagg caaggtctac
    37441 tatgctaaca atcaagaaga ccacgaccgc aatgtcgctg aacatgtcaa cagcaaatta
    37501 aactaaacaa actaaaatta tgtgatactt cacataattt tctttagaaa atattatcag
    37561 aagaaagttg agaaaaatgg cagaaaaaac atatcctatg acccttgagg aaaaggagaa
    37621 acttgaaaaa gaattagaag aattgaaatt ggttcgtcga ccagaagtgg tagaacgcat
    37681 taagattgcc cgttcatacg gtgatctttc agaaaacagt gagtacgaag cagctaagga
    37741 tgaacaagcc tttgtcgaag gacaaatctc tagcttagaa acaaaaatcc gctatgctga
    37801 aatcgtcaat agcgacgcag ttgcccagga cgaagtagcg attggtaaaa cagtcaccat
    37861 ccaagaaatt ggtgaggacg aagaagaagt ttatattatc gtaggttcag ctggtgcgga
    37921 tgcctttgca ggtaaggttt caaatgaaag cccaattggg caggccttga ttggcaagaa
    37981 aacaggtgac acagcaacca ttgaaacgcc tgttggtagc tatgatgtaa aaatcttgaa
    38041 ggttgaaaaa acagcctaaa aacagaaaaa ggagtgggga ggcgatgtgc ttcactcact
    38101 cctttttcca ttttgctatt cttcgaaaat ctcttcaaac cacgtcagcg tcgccttgcc
    38161 gtatgtatgg ttactgactt cgtcagtttc atctacaacc tcaaaacagt gttttgagct
    38221 aacttcgtca gtttcatcta caacctcaaa accatgtttt gagccgactt cgtcagtttc
    38281 atctacaacc tcaaaaccat gctttgagct gacttcgtca gtttcatcta caacctcaaa
    38341 accatgcttt gagctgactt cgtcagttct atctacaacc tcaaaacagt gttttgagca
    38401 acctgcggct agtttcctag tttgctcttt gatttttatt gagtattaga tgtatagtgc
    38461 attgaagtta aaaatagtac acttt
//
LOCUS       DBERXF010000019        36944 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.19, whole genome shotgun sequence.
ACCESSION   DBERXF010000019 DBERXF010000000
VERSION     DBERXF010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 36944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36944
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.19"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            80..460
                     /locus_tag="ACL8JK_001066"
     CDS             80..460
                     /locus_tag="ACL8JK_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785963.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTAATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGGVSLIPFLGW
                     VGGILAIIGGSLFLATLKKFKSEE"
     gene            995..1687
                     /locus_tag="ACL8JK_001067"
     CDS             995..1687
                     /locus_tag="ACL8JK_001067"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HGS1785964.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1740..4151
                     /locus_tag="ACL8JK_001068"
     CDS             1740..4151
                     /locus_tag="ACL8JK_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGS1785965.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASNGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAALKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLQNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4401..5102
                     /locus_tag="ACL8JK_001069"
     CDS             4401..5102
                     /locus_tag="ACL8JK_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1785966.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANCDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5104..7812
                     /locus_tag="ACL8JK_001070"
     CDS             5104..7812
                     /locus_tag="ACL8JK_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGS1785967.1"
                     /translation="MIKRKTYWKDLVQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAS
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIITKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSLLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTTKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7908..8399)
                     /gene="tpx"
                     /locus_tag="ACL8JK_001071"
     CDS             complement(7908..8399)
                     /gene="tpx"
                     /locus_tag="ACL8JK_001071"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HGS1785968.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEDLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8522..9451)
                     /gene="psaA"
                     /locus_tag="ACL8JK_001072"
     CDS             complement(8522..9451)
                     /gene="psaA"
                     /locus_tag="ACL8JK_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HGS1785969.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9483..10331)
                     /locus_tag="ACL8JK_001073"
     CDS             complement(9483..10331)
                     /locus_tag="ACL8JK_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGS1785970.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10328..11050)
                     /locus_tag="ACL8JK_001074"
     CDS             complement(10328..11050)
                     /locus_tag="ACL8JK_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGS1785971.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11350..13242
                     /gene="pepO"
                     /locus_tag="ACL8JK_001075"
     CDS             11350..13242
                     /gene="pepO"
                     /locus_tag="ACL8JK_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HGS1785972.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPILSLLKEFQELETFADF
                     IAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13365..13994)
                     /locus_tag="ACL8JK_001076"
     CDS             complement(13365..13994)
                     /locus_tag="ACL8JK_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGS1785973.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            14988..17210
                     /locus_tag="ACL8JK_001077"
     CDS             14988..17210
                     /locus_tag="ACL8JK_001077"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HGS1785974.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLGDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17240..17683
                     /gene="dtd"
                     /locus_tag="ACL8JK_001078"
     CDS             17240..17683
                     /gene="dtd"
                     /locus_tag="ACL8JK_001078"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGS1785975.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKLDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(18155..18568)
                     /locus_tag="ACL8JK_001079"
     CDS             complement(18155..18568)
                     /locus_tag="ACL8JK_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785976.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFIIRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(18699..19406)
                     /locus_tag="ACL8JK_001080"
     CDS             complement(18699..19406)
                     /locus_tag="ACL8JK_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0034257 - nicotinamide riboside
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter family
                     protein"
                     /protein_id="HGS1785977.1"
                     /translation="MKKSLKIFATSKWFDLFGVALVVGIAIASGYLNSRLDKFVDWGP
                     WTALVPFGLISVTNVGISMLSTRFTGKLSKWGNYFSIVNTILSGAIDYILGNKAAIIT
                     YPVTFLIYTFAIKKWKASQEGRPNQMSQKQVKLTVIIISIIAFLFAFVTNYIGYEGKM
                     NLLAYVTTIAFALSLIANALNALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFY
                     ILNAIGALFVWNDEEVR"
     gene            complement(19526..20176)
                     /locus_tag="ACL8JK_001081"
     CDS             complement(19526..20176)
                     /locus_tag="ACL8JK_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGS1785978.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     NFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            20288..21130
                     /locus_tag="ACL8JK_001082"
     CDS             20288..21130
                     /locus_tag="ACL8JK_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS1785979.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            21206..21643
                     /locus_tag="ACL8JK_001083"
     CDS             21206..21643
                     /locus_tag="ACL8JK_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGS1785980.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            21711..22013
                     /locus_tag="ACL8JK_001084"
     CDS             21711..22013
                     /locus_tag="ACL8JK_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785981.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(22104..23177)
                     /locus_tag="ACL8JK_001085"
     CDS             complement(22104..23177)
                     /locus_tag="ACL8JK_001085"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HGS1785982.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            23333..24010
                     /locus_tag="ACL8JK_001086"
     CDS             23333..24010
                     /locus_tag="ACL8JK_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1785983.1"
                     /translation="MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            24003..24977
                     /locus_tag="ACL8JK_001087"
     CDS             24003..24977
                     /locus_tag="ACL8JK_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HGS1785984.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(25026..26969)
                     /gene="thrS"
                     /locus_tag="ACL8JK_001088"
     CDS             complement(25026..26969)
                     /gene="thrS"
                     /locus_tag="ACL8JK_001088"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGS1785985.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(27027..27203)
                     /locus_tag="ACL8JK_001089"
     CDS             complement(27027..27203)
                     /locus_tag="ACL8JK_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGS1785986.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            complement(27210..27350)
                     /locus_tag="ACL8JK_001090"
     CDS             complement(27210..27350)
                     /locus_tag="ACL8JK_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGS1785987.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(27781..27981)
                     /locus_tag="ACL8JK_001091"
     CDS             complement(27781..27981)
                     /locus_tag="ACL8JK_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1785988.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKELYINNLL
                     FFTPLVILIISLLYSYRFRFSL"
     gene            28220..28849
                     /locus_tag="ACL8JK_001092"
     CDS             28220..28849
                     /locus_tag="ACL8JK_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS1785989.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKDQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            28990..29259
                     /gene="rpsO"
                     /locus_tag="ACL8JK_001093"
     CDS             28990..29259
                     /gene="rpsO"
                     /locus_tag="ACL8JK_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGS1785990.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            30075..30689
                     /locus_tag="ACL8JK_001094"
     CDS             30075..30689
                     /locus_tag="ACL8JK_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HGS1785991.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(30981..31730)
                     /locus_tag="ACL8JK_001095"
     CDS             complement(30981..31730)
                     /locus_tag="ACL8JK_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGS1785992.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            31863..34199
                     /locus_tag="ACL8JK_001096"
     CDS             31863..34199
                     /locus_tag="ACL8JK_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGS1785993.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            34300..34977
                     /locus_tag="ACL8JK_001097"
     CDS             34300..34977
                     /locus_tag="ACL8JK_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGS1785994.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            34964..35761
                     /locus_tag="ACL8JK_001098"
     CDS             34964..35761
                     /locus_tag="ACL8JK_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGS1785995.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQEDDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIATLLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            35778..36881
                     /locus_tag="ACL8JK_001099"
     CDS             35778..36881
                     /locus_tag="ACL8JK_001099"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS1785996.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
BASE COUNT        10777 a         6932 c         8480 g        10755 t
ORIGIN      
        1 tataatatca gaaaatactt tttttaaaag caaatatgat acaattttat ttgaaaaaaa
       61 taaaaaagga gattttatta tgaaattaaa aacacttgct ttaattagtg gtatcgtcgg
      121 tcttgtggga ggaattttac ttcttattgg tccttttgtc ttgttgggaa cagcggtaaa
      181 cacagctgct acaactctta atggaggagc tactgcaggg gctttttcag gtgttgcctt
      241 actcttgaat gccttgaaga ttgcaaatct tgttcttggt atcattgcta ttgtttacta
      301 taaaggagat aagcgtgtag gtgcagctcc gtctgtacta atgattgttt ctggtggagt
      361 tagtctcatt ccattcttag gatgggttgg ggggattctt gctattatcg gaggatctct
      421 attccttgca acattgaaga aattcaaatc agaagaataa aaggtatttt agcatgaaaa
      481 gaacaaaaaa gtttatcggt ataggagtag ctctattatc tctttctttt ctagttgcat
      541 gtggaacata aagttcaaag aatacttcaa caagtaatga tgagaagaca gtagcaacat
      601 ccaatagttc aaaagaaaca atcactttcg atacaccggt tgtaacagac aatgcgattg
      661 aatcaatacg cacttatgca gattatatag atctttataa aaatattttt gatgattatt
      721 ttactaaagc tgaggaaggt ttcaaaggca cagctatgga aaataatgac tcgtttacta
      781 aactaaaaga gtcaactcaa aaattattcg atgcgcagaa aaaaaggtta aataatgaag
      841 atagaataga aacaaccaaa aacaatgtga ttgccaaaca ttgtcaaaca gtcctttcct
      901 ttttggtttt gactagcttt tttgtgaaaa attgtgtaaa atagaataga taaacgaggg
      961 gaaacctcgg aaaatttaaa ggagaatcca tctaatggta aaattggttt ttgctcgcca
     1021 cggtgagtct gaatggaaca aagctaacct tttcactggt tgggctgatg ttgatttgtc
     1081 tgaaaaaggt acacaacaag cgattgacgc tggtaaattg atcaaagaag ctggtatcga
     1141 atttgaccaa gcttacactt cagtattgaa acgtgctatc aaaacaacta acttggctct
     1201 tgaagcttct gaccaattgt gggttccagt tgaaaaatca tggcgcttga acgaacgtca
     1261 ctacggtggt ttgactggta aaaacaaagc tgaagctgct gaacaatttg gtgatgagca
     1321 agttcacatc tggcgtcgtt catacgatgt attgcctcca aacatggacc gtgatgatga
     1381 gcactcagct cacacagacc gtcgttacgc ttcacttgac gactcagtta tcccagatgc
     1441 tgaaaacttg aaagtgactt tggaacgtgc tcttccattc tgggaagata aaatcgctcc
     1501 agctcttaaa gatggtaaaa acgtattcgt aggagctcac ggtaactcaa tccgtgccct
     1561 tgtaaaacac atcaaaggtt tgtcagatga tgagatcatg gacgtggaaa tccctaactt
     1621 cccaccattg gtattcgaat tcgacgaaaa attgaacgtt gtttctgaat actaccttgg
     1681 aaaataaaaa attgtaagcc taggattgat ttctaggctt tttatgttag tatggaagta
     1741 tgataaggaa taaaaaacaa gattatgtac tggcctacaa gcaaccagtt tcaaccactt
     1801 acatgggttg ggaagaagaa gctttaccga taggtaatgg ttctttagga gcaaaagtat
     1861 ttggccttat aggggctgaa cggattcaat ttaatgaaaa aagtctctgg tctggaggtc
     1921 cacttcctga tagttcagat tatcagggtg gaaatcttca ggatcagtat gtttttttag
     1981 ctgagattcg gcaggctttg gagaagagag attacaatct ggctaaggaa ctggctgagc
     2041 agcacctaat tgggccaaaa acgagtcaat atgggaccta tctgtctttt ggggatattc
     2101 acattgagtt cagccagcaa ggtacgactt tgtctcaggt gacggactat cagagacagt
     2161 tgaatattag taaggcactt gcgacgactt cttatgtcta taagggaacg cgatttgaac
     2221 gtgaagcttt tgcgagtttt ccagatgatc tcttggttca atgttttact aaggaagggt
     2281 tggaaactct agattttact atagaactat ccttgacctg tgatttggct tctaatggaa
     2341 agtatgagca ggaaaaatct gattacaagg agtgtaagtt ggatattact gattctcata
     2401 tcttgatgaa gggaagagtt aaggataatg atctgcggtt tgctagttat ctagcttggg
     2461 aaacggatgg agatattaga gtttggtcag atagggttca gatatcagga gccagttatg
     2521 ccaatctctt cttggccgct aagacggatt ttgcccaaaa tcctgctagc aattatcgca
     2581 agaaactaga tttagagcaa caggtgatag acttggtgga cacagctaaa gaaaagggct
     2641 atacccaatt gaaatcaagg catatcgagg actaccaagc cttattccag cgtgttcaat
     2701 tggatttgga agctgatgtt gacgcatcca ctacagatga tttgttaaaa aattataagc
     2761 cacaagaagg gcaggctttg gaggagctgt tcttccagta tggacggtat ttattgatta
     2821 gttcgtccag agactgccca gatgctctac cagctaacct acagggagtc tggaatgcgg
     2881 tcgacaatcc tccttggaat tcggactatc acttaaatgt caatctgcag atgaattatt
     2941 ggccagccta tgttaccaat cttctagaga cggtctttcc agtcatcaac tatgtagatg
     3001 atttgcgtgt ctatggtcgt ctagcggctt taaagtatgc aggaatcgtc tctcagaaag
     3061 gtgaggaaaa tggttggttg gttcatactc aagcgactcc ctttggttgg acggcacctg
     3121 gttgggatta ctattggggt tggtcaccag ctgccaatgc gtggatgatg caaaccgttt
     3181 atgaagccta ttcattttat agggaccaag actatcttag ggagaaaatt tatcccatgt
     3241 tgagggaaac ggttcgtttt tggaatgcct ttttacataa ggatcagcag gcgcagcgtt
     3301 gggtgtcttc tccgtcttat tccccagaac atgggccgat ttcgattggc aatacctatg
     3361 accaatctct gatttggcag ttatttcatg attttattca ggctgctcag gaattgggac
     3421 tggatgagga cttgttgact gaggttaagg agaagtctga tttactaaat cctttgcaaa
     3481 tcactcaatc tggtcgaatc agggagtggt atgaggagga agagcagtat tttcaaaatg
     3541 agaaagtgga ggcccagcat cggcacgctt cccatctagt gggactctat cctggcaatc
     3601 tctttagcta caagggacaa gagtatattg aagcggcgcg tgctagcctc aatgatcgtg
     3661 gagatggcgg cacaggctgg tccaaggcta ataagatcaa tctctgggcg cgtttgggag
     3721 atggcaatcg agcccataaa ttattggcag agcagttaaa gacatccacc ttgcaaaatc
     3781 tttggtgtag ccatcctcct tttcagatag atggtaattt tggtgctact agtggcatgg
     3841 cagaaatgtt actccagtct catgcagctt atctggtacc tctagctgcc ctacctgatg
     3901 cttggtcaac aggttctgtt tcaggcttaa tggcacgtgg acattttgaa gtgagcatga
     3961 gctgggaaga taaaaaactc ttacagttga ccattttatc aaggagtgga ggagatttgc
     4021 gagtttctta tccagatatt gagaagagtg tgattaaaat gaatcaagaa aaaataaaag
     4081 cgaaatgcat ggggaaagat tgtatttcgg tggcaacagc agaaggtgat cttgttcaat
     4141 tttattttta agaagatgtt ataaggcagt aatttgaaac tgccttttaa taaggattta
     4201 agaatataag cagttttcaa ctagttgaaa aaacgttata atgataatag gaagtaatac
     4261 tcaatgaaaa tcaaagagca caaactagga agctagccgc aggttgctca aaacagtgtt
     4321 ttgaggttgc agatggaagc tgacgtggtt tgaagagaga ttttcgagga gtataatttg
     4381 tttgatagag ggtgggtctg atggcttata ttgagatgaa acactgttac aagcgttatc
     4441 aggttgggga cacggagatt gtggccaatt gtgatgtgaa ttttgagatt gaaaaggggg
     4501 agctggttat tatccttggt gcttcaggtg caggcaagtc aacagttctt aaccttcttg
     4561 ggggaatgga taccaatgat gaaggggaaa tctggattga tggtgttaat attgcggatt
     4621 atagttccca ccagcgcacc aattaccgta gaaatgatgt ggggtttgtt tttcagtttt
     4681 ataatctagt ttctaatctg acagctaagg aaaatgtgga actggcttct gaaattgtga
     4741 cagatgcctt gaatcctgat caagtcttga cagatgtagg tctggctcat cgtctcaata
     4801 actttccagc ccagctttct ggaggggagc aacagcgagt ctccattgca cgcgcggtag
     4861 ccaaaaatcc taaaattctc ctttgtgatg aaccgactgg agccttggat tatcagacgg
     4921 gcaagcaggt tttgaaaatt ctccaagaca tgtctcgtca aaagggagcg acggtgatca
     4981 tcgtgactca taatggagct ttggcgccca ttgctgatcg cgtgattcaa atgcacgatg
     5041 ccagtgtcaa ggatgtggtg ctcaaccagc atcctcagga tattgacagt ttggagtact
     5101 agcatgatca agcgaaaaac ttattggaag gacttagttc agtccttcac aggctccaag
     5161 gggcgttttt tatccatctt gatcctgatg atgttgggat ctctagcctt agtaggcctc
     5221 aaagtaacca gtcccaacat ggaggcgaca gctaatgctt atttaacaac tgctcaaacc
     5281 ttggatttgg cagtcatgtc taactatggc ttggatcaag cagaccaaga agaactaaaa
     5341 cagacggagg gcgcagaggt cgagtttggc tatttgacag atgtgactat ggataatggg
     5401 caggatgcca ttcggctgta ctccaaacca gagcgaattt caacctttca gctaagaaag
     5461 ggacgacttc ctcagtcaga caaggaaatc gctttggcca ctcatttgca aggccaatac
     5521 agcgtgggac aggagattag ttttaaagaa aaagaagagg gtcattcctc tttaaaagac
     5581 catacttata ccattactgg ttttgtggat tcggctgaaa tcctctccca gcgagatatg
     5641 ggctacgcag gaagtggaag tgggactctg acagcctatg gggtgatttt acctagtcag
     5701 tttgatcaga aagtctacaa tatagctcgt ttgaaatatc aagatttagc aggtttaaat
     5761 gccttttcat cagcttatga agaaaaatcc aagcaacatc aggaagacct tgaacaaact
     5821 ttatcagata atggcaaggt acgtctgcaa cttttgaaaa aagaaggaca agagtctcta
     5881 gacaaggggc aagagaccct tgacaaggct cagactaatt tgcaggaagg caagcgtcgt
     5941 ttagcagctg ctcaagctcg tatacaggct caagaaagtc aactagcctt gtttcctcaa
     6001 gttcagagag agcaggctag tgctcaactt acccaagcca agcaggaatt gggcaaggaa
     6061 gaggataaac taaagcaagc tgaacaaaat ctagcccaag aaaaggaaaa attagaaaaa
     6121 catcagcaag tcttggacga tttggcggag ccaaggtatc aggtctataa tcgtcagacc
     6181 atgccaggtg gtcagggcta tcttatgtat agcaatgctt catccagtat tcgagcagtg
     6241 ggcaatatct ttcctgtggt actttatgcc gtagcatcca tggtgacctt tacgaccatg
     6301 actcgctttg tagacgaaga gcgaactcat gcagggattt ttaaggcctt gggttaccgt
     6361 agtaaggata ttatcaccaa gtttctcctt tatggactag tagctgggac tgtcggaacg
     6421 gctctaggta gtatacttgg tcattatttg ctagccagtg taatttcaag tgtcattaca
     6481 aaaggcatgg tggtgggaga aacccagatt cagttctatt ggacctatag cttactagct
     6541 cttgtcttga gcttgttggc gagtgtgtta ccagcctatc tggtggcttg gagggaactt
     6601 catgccgaag cagcccagct tctacttcct aaacctcctg tcaaaggagc taaaatctta
     6661 ttggagcgta tcggttttat ctggcgtcgt ctcagtttta ctcataaggt aacagcccgc
     6721 aacatctttc gttataagca gagaatgttg atgacaatct ttggtgtggc aggttctgta
     6781 gctctgctct ttgcaggttt gggaatccaa tcttctgtag caggagttcc gtctaaacag
     6841 tttcaacaaa tccaacagta tcagatgctt gtctctgaaa atcctagtgc gaccaatcag
     6901 gacaaggtag agctagcaga agtattgaaa gggcaggaga tactagccta ccagaaaatc
     6961 tattctaaaa cgctagacaa ggatttcaaa ggcaaggctg gtcttcaaaa cattactctt
     7021 atgatgatag agaaggaaga tttgactccc tttatccatc ttcaacatca tcagcaggag
     7081 ctgacattaa aagatggcat cgttattaca gctaaactcg cccagctggc aggtgtcaag
     7141 gttgggcaga ctttagaaat tgaaggtaag gaactaaagg tcgctgctat tactgagaac
     7201 tacgttggtc actttattta tatgagtcag gctagctatg agcaacttta cggacagcta
     7261 ccccaagcca acacttatct ggtctcatta agggatacca gtgcaactag tatcgaaagt
     7321 caggcgggct tgcttatgaa tcaatctgcg gtgtccagcg ttgtccaaaa tgcttcagcc
     7381 attcgactct tcgactctat cgctagctca ctcaatcaga ccatgaccat cttggtcatc
     7441 gtatcggttc tattagctat tgtcatcctt tacaatctga ccaatatcaa cgtagctgag
     7501 agaatccgtg aactctccac taccaaggtt ctcggttttc ataataatga agtcacactc
     7561 tacatttacc gtgagacgat tgtgctatcc cttgtgggaa tcgtacttgg tctggtagct
     7621 ggtttctatt tacaccaatt tttgattcaa atgatttcgc ctgcgactat tctcttttat
     7681 ccgcaggtag gctgggaagt ctatgtaatc ccagtggcag cagtaagcat cattttgacc
     7741 ttgcttggtt tcttcgtcaa ttattatctg agaaaggttg atatgttaga agccctgaaa
     7801 tctgtagagt aaggtagtta tttttagctg attgaacttc tatttactaa tattcaaaaa
     7861 tcctccgttt caaagagcag ggaactcttt gtgacagagg attttttcta tagggcttta
     7921 gcagctgcaa ttgcggcttc gaagtttggc tcagaattga tattatccac gtattcaacg
     7981 tagcgaatcg tattgtcagt atcgaggaca aagactgcgc gtgctaatag gtgccattcg
     8041 ttgatcaaga gggcataatc gcgcccgaaa gaatggtcaa agtagtctga aagcataatg
     8101 gcattgtcaa ggtcttcagc accgcaccaa cgtttttgag caaaaggtag gtccattgaa
     8161 acagtcaata cgaccgtgtt gtccagtcca gccaattctt cattaaaacg acgtgtttga
     8221 gttgagcaga tgcctgtatc gatagaagga acgacactca agactttttt cttgccatca
     8281 aaatcagcca gagatttttt agaaagatct gttgtagtaa gagaaaaatc aagcgccttg
     8341 tcgccgactt gtagttgttt acctgtaaag ctcacaggat ttccgagaaa agttaccata
     8401 ggatactcca atcttttttc ttccattgta tctgaaacag tcagaatttt ccaatgattt
     8461 gaccggaaat gtgggcatag aaaaaacgcc agctcacatg agaatgacgt ttttcagagg
     8521 cttattttgc caatccttca gcaatcttgt caaggttgta tttcatcatg ctgtagtagc
     8581 tgtcgccttc tttaccttgt tctgcgatag agtcagtaaa gatttgtgcg tagattggga
     8641 tgtttgtgtc ttgagaaaca gttttcattg gacggtcatc cacacttgat tctacaaaga
     8701 gtgatggaac ttttgtttgg cgaagttttt caaccaaggt cttgatttgt tcaggagttc
     8761 cttcttcttc agtattgatt tcccagatgt aggcacttgg aacaccatag gctttagaga
     8821 agtatttgaa tgctccttcg ctggttacaa tgagtttctt ttcagcaggg atcttattaa
     8881 atttatcctt actttcttta tcaagtttgt ctaacttatc agtatattct ttgagatttt
     8941 tttcatagaa ttctttattg ttagggtctt tggcgctcaa ttgtttggcg atatttttag
     9001 caaaaataat accgttttca aggttaagcc aagcgtgtgg gtcttctttt cctttttcat
     9061 tttgaccttc aaggtagata acatcaacgc cgtcgctgac tgcgaagtag tctttgtttt
     9121 cagttttctt ggcattttct accaattttg taaaccaagc attgccacct gtttcaaggt
     9181 tgataccgtt atagaaaatc aaatcagcct cagaagtttt cttaacgtct tcaggaagtg
     9241 gttcgtattc gtgtgggtct tgcccaatcg gaacgatact atgaaggtca attttgtcac
     9301 cagcaatatt tttagtaata tcagcgatga ttgagtttgt agcaacaact tttagttttt
     9361 gaccagaagt tgtatctttt tttccgctag cacatgctac aagaatgatt gcagaaagaa
     9421 agagaacgag taatgtacct aattttttca ttagatcctc caatttatta gggctttgcc
     9481 ccttatttta acaaatgttt atttttcagt ttcaaatatc gttgtttggg agcgataaag
     9541 aagctaatga gaaagaaact agcagctgta agcacgatac tagaacctgc cgcaacatta
     9601 aaactatagc caataaagag tcccaaaact gaagcagtag ctccgaaggt tgaggaaagg
     9661 aaaatcatac ttttcagact attagcatac agataagcag ttgcagctgg ggtaatcagc
     9721 atggctacaa tcaggatagt tccgacactt tgcatggctg tcacagacac gagagtcagg
     9781 agtaccatga gaaggtagtg atagaaattg acaggcattc ccatggcttt agccaagagt
     9841 tcatcaaagg aagttatcaa gagttgcttg aagaaaatcc agattaacaa gaggatggct
     9901 gcccccacac ccatagtaat aaacatatcc gtatcttgga cggccaggat attaccaaaa
     9961 aggatatgga aaaggtcagt tgaactttta gcgacaccaa tcaagatgat accgagggct
    10021 aagaaagaag aaaaggtaat gccgatggcg gtatcgcttt tgataatcga gtttcctttg
    10081 atgtaggtaa tgatgatggc agctagcaat ccaaagacaa tggctccgat aaagaagtca
    10141 aggcccaaga tgaaggagag ggctacacct ggtaagacag catgtgaaat ggcatctccc
    10201 atgagtgaca tcccgcgtag aataatgaaa catcccacag ctccagctac aatcccgacg
    10261 acaatagctg ttatcaaggc attttgtagg aaatggaatt tttgcaatcc atcgataaat
    10321 tctgcaatca taggtcacct ccattgaaaa agagttgatt accgtaagct tcttttagat
    10381 tggtttcggt aaaagtttct tttgttggac caaaggcaat cacttctcga ttgacaagta
    10441 agacttgatc gaagtagtgg ggaatcttgc tgaggtcgtg gtgaacgatg agaaccgtct
    10501 tcccagcttt tttcaaatct ctcagcgtat tcatgatgat ttcctcactg acagagtcaa
    10561 tcccagcaaa gggttcatcc aagaggatat agtcggcttc ctgcaccaaa catctggcaa
    10621 tcaagacccg ctggaattga cctccagaca gttgactaat ttgacgttca gcgtagtcag
    10681 ctaggccgac gatttcaagg gcctcttgca ctttcttcca atgtttagcc tttaaacttc
    10741 gaaagagagg aatagaggga aatagtccta acgagacgca ttccttgacc ttgatgggaa
    10801 agttgtagtc gatattgatt ttttgttcga cataggcaat tcggtgtaag gattttttaa
    10861 cttccttgtc atcgagaaat gcctgacctt gatgtgggat aattcccagc atacctttta
    10921 atagtgttga tttcccagcg ccgtttggac caatgatgcc ggtaattgtt ggtccatgga
    10981 gcactagtga aatatcctta agtgccaacg tttctttgta ggagacactg aggttttcga
    11041 tacgtatcat aaacttgtat tcctcctgtc tcttaatata cattaaaaaa aaaattaagt
    11101 caagttaatt tttgaaaaaa ttaaaataat aactgaaaaa tagattctaa agataacttt
    11161 caggataaat ttctaaatta taaaacgcat agtatgcata gtatcaagtg taaaaaactt
    11221 ggaattatgc gttttatcat ggaaagattc tttataatag ctaaaaaata atagttaaat
    11281 ggttactaat tgcattccct agtgattttt gttaagataa aggcaaatac aaatgaaagc
    11341 gagaacaaga tgacacgtta tcaagatgat ttttatgatg ctatcaatgg agaatggcaa
    11401 cagacagctg aaatcccagc agataagtct caaacaggag gttttgttga tttagaccag
    11461 gaaattgaag acttgatgct ggcgacaaca gacaagtggt tagcaggtga agaagtgcct
    11521 gaggatgcta tcttggaaaa ctttgtcaaa taccaccgcc tagttcgtga ttttgacaag
    11581 agagaagctg acggtatcac acctatctta tcactcctta aagaatttca agaattggag
    11641 acttttgcgg attttatagc taaactagca gagtttgagc ttgcaggaaa accaaacttc
    11701 cttccttttg gtgtatcgcc agactttatg gatgctagaa tcaatgttct atgggctagc
    11761 gctccaagca caatcttgcc agatacgacc tactatgcag aagaacatcc tcagcgcgaa
    11821 gagctcttga ctctttggaa agaaagcagc gcaaatctcc tcaaggctta tgatttctct
    11881 gatgaagaaa ttgaagactt gctagaaaaa agacttgaat tggaccgccg agttgcggca
    11941 gtggtgctct ctaatgaaga aagttcagaa tatgctaaac tctatcatcc atattcttac
    12001 gaagatttca agaaattcgc gcctgcccta cctttggatg acttcttcaa agcagttatt
    12061 gggcaattac cagacaaggt tattgtagac gaggaacgtt tctggcaagc agcagagcaa
    12121 ttctacagtg aggaagcctg gtctctcctt aaagcaacct tgattttgag tgttgtcaat
    12181 ctttcaacca gctatttaac agaggatatc cgtgttttgt ctggtgccta cagccgtgcc
    12241 ctttctggag ttccagaggc aaaagataag gtcaaagcag cttatcatct agcacaagaa
    12301 cctttcaagc aagccctggg tctttggtac gcccgtgaga agttctctcc agaagccaag
    12361 gcggatgtgg agaaaaaagt ggcaaccatg attgatgtct ataaggagcg tctgcttaag
    12421 aatgactggc tcactccaga aacctgtaaa caggctatcg tgaagctcaa tgtgatcaaa
    12481 ccttatattg gctatccaga agaattgcct gcacgttaca aggataaggt agtgaatgaa
    12541 actgccagtc tttttgagaa tgctctagcc tttgcgcgtg tggaaatcaa gcacagttgg
    12601 agtaagtgga accagcctgt agattataag gaatggggca tgcctgctca tatggtcaat
    12661 gcctactaca atcctcagaa gaacctgatt gtctttccag cggccatttt acaggcgcct
    12721 ttctatgact tgcatcagtc atcttctgct aactacggtg gtattggggc agtgattgcc
    12781 catgaaattt cccacgcctt tgatactaac ggggcttcct ttgacgaaaa tggtagcctc
    12841 aaggattggt ggacagagag cgactatgct gccttcaagg agaaaacaca aaaagtcatt
    12901 gaccaatttg atggacagga ttcttatgga gcaaccatta acggtaaatt gactgtatca
    12961 gaaaacgtgg ctgacttggg aggaatcgca gcagcgcttg aagcagctaa gagagaagca
    13021 gacttctcag cagaagagtt cttctacaac ttcggtcgca tctggcgcat gaaaggtcga
    13081 ccagaattta tgaaactttt ggctagcgtc gatgtgcacg caccagccaa actccgtgtc
    13141 aatgtgcaag taccaaactt cgacgatttc tttacaacct atgatgtcaa agaaggagac
    13201 ggaatgtggc gttcaccaga ggagcgcgtg attatttggt aatacaaaaa atctagtcat
    13261 cagaaaaaag gcatccaatc acgtgtgaaa accttgatag gatgcctttt gtaatagaaa
    13321 gatttgctgg atagtttact taaatttcga ttgtcatcat cttgctagaa aaagggattg
    13381 aaggcctttt cgtgagcgat agtagtagct ggaccatgtc ctggatagac atcgtagttt
    13441 ggtagggtga agagttgggt ctggatacta tgaaggagtt gctccatgct accagtcgga
    13501 aggtcggtcc gtccgatagt ttcgcggaat agagcatctc ccgtcaagac taggtgagca
    13561 tcaggaaaga ctagggaaac accaccgata gagtgccctg gggtcggtag aaccttaaaa
    13621 cgaaattcct ctagttggta ttcttcgtga aagacaaagg tgtgttctgc aggttttgtg
    13681 accacatctg ccatatcatc gtggcgaggg agaccggaga gattatcgac aggagtgtag
    13741 agccagctgg cttcgctctc tgcgatatag acaggaggat tgccaaacgt ctcgcgaacc
    13801 aagtccagac tcatgatatg gtcataatgg gcgtgggtca agagaatagc acagatcggt
    13861 ttgttgatct tctcgattgt ctgacgaatg gcttcccaat gactaccagg atcgacgacg
    13921 atgaggtgct tttcgccttc tagataatag gtattttcat aggcaacagg attcacggtt
    13981 ttatggattt tcatactagc tccaatctca aagaatgtac taatactctt cgaaaatctc
    14041 ttcaaaccgc gtcaacttta tctgcaacct caaagcagtg ctttgaacag cctgcggcta
    14101 gctttctagt ttgctctttg attttcattg agtataaatt aagtatagca cagttaggga
    14161 gaataggtaa ggatttaaaa tgaacttaaa aaccagcatg actagatgaa gacaggctgg
    14221 ttatcaattt atcaatattg gaaaggtgtc aattgccctt cataggttgc ataaactccg
    14281 tcattagctt gtttgataga cgtgatgttt agagtgctac cgtagttggc ttctcatttg
    14341 tcgctatatt cactataagt tatcctactg ggcaggttct ggtcgttagc atagtattga
    14401 acgagttttt tatagctttg ctggctgaat aggaacaggc agcaaactcc taacattagg
    14461 agagcaaaga tagaaatagc agtttttttc ataggtattc tccttataaa ctaaaggata
    14521 gaagaaagta tcttgaggat ttttatactc ttcaaaaatc tcttcaaacc gcgtcaacgt
    14581 cgccttgccg tatatatgtg actgactttg tcagtcttat ctacaacctc aaagcagtgc
    14641 tttgagcaac ctgcggctag tttcctagtt tgctctttga ttttcattga gtattaattc
    14701 caaaatccag tcaaggtacc agtgtatgtg atacgagttc caccgtttat ctttcgtatc
    14761 ttcaatggaa ttggggaaat cagaaagtct ttgggttaca atatggtttc cgttcttcta
    14821 tctctccttc tatcacctaa gtttaaaatc taacttcgta gtatattatg ggccaataat
    14881 tcagaattat caagcaattt tgaattattt ttttcttatt ctgttccaat ctagttttca
    14941 tattcttaaa aaagtgataa aatggtagga agaattggag agtagagatg ccgaaagaag
    15001 tgaatttaac aggcgaagaa gttgtcgctt taaccaaaga atatttaacg gaagaggatg
    15061 ttcattttgt ccataaggcc ttggtctatg ctgttgaatg ccacagtggt caatatcgca
    15121 aatcaggcga gccttatatc attcacccta tccaagtggc aggtatttta gctaagctaa
    15181 agctggatgc tgtaacagta gcttgtggat tcttgcatga tgtggtggaa gatacagatg
    15241 cgaccttggg cgatttggaa agagagtttg gtcctgatgt gcgggtgatt gttgacggag
    15301 ttaccaagct tggcaaggtc gagtacaaat cgatcgagga gcaattagcg gaaaatcatc
    15361 gcaagatgct catggccatg tctgaggaca tccgcgttat tttggtcaaa ctgtctgacc
    15421 gcttgcacaa tatgcggacc ctgaaacatc ttcgaaaaga caagcaggag cgtatttcca
    15481 aagaaaccat ggaaatctat gccccacttg cccatcgttt ggggatttcc agtgtcaaat
    15541 gggaattaga agacttgtct ttccgttatc tcaatccaac ggagttttac aagattaccc
    15601 atatgatgaa ggaaaagcgc agggagcgtg aggccttggt ggatgaggta gtcacaaaat
    15661 tagaggagta cacgacagaa cgtcacttga aagggaagat ttatggtcgt cccaagcata
    15721 tttactcaat tttccgcaaa atgcaggaca agagaaaacg gtttgaggaa atctatgatc
    15781 tgattgctat tcgttgtatt ttagataccc aaagtgatgt ttatgccatg cttggttacg
    15841 tgcatgaatt ttggaaaccg atgccaggtc gcttcaaaga ctatattgcc aaccgcaagg
    15901 ccaatggtta tcagtctatc catacgactg tttatggacc aaaagggccg attgaattcc
    15961 agattcgaac caaggaaatg cacgaggtgg ctgagtacgg ggttgcggct cactgggctt
    16021 ataagaaagg tataaagggg caagttaaca gcaaggaatc agctattgga atgaactgga
    16081 tcaaggagat gatggagctc caagaccagg ctgatgatgc taaggaattt gtggactctg
    16141 ttaaggaaaa ctatttggct gaggagattt acgtttttac cccagatgga gctgtccgtt
    16201 cccttcccaa agattcagga ccgattgatt ttgcctacga aatccatacc aaggtcggtg
    16261 aaaaagcaac tggtgccaag gtcaatggcc gcatggttcc actgacaacc aagttaaaga
    16321 caggggatca ggttgaaatt atcgccaacc cgaactcctt tggacctagc cgtgactggc
    16381 tcaatatggt caagactagc aaggcgcgca ataagattcg ccagttcttt aaaaaccaag
    16441 ataaggaatt gtctgtcaac aagggtcgtg agatgctgat ggctcagttc caagaaaatg
    16501 gctatgtggc aaataaattt atggacaagc gccacatgga tcaagttctg caaaagacca
    16561 gttacaagac agaagactcc ctctttgcgg ccattggttt tggggaaatc ggtgcgatta
    16621 ccgtctttaa ccgtctgact gaaaaggaac gccgtgagga agagcgtgcc aaggccaagg
    16681 ctgaggcaga ggagcttgtc aaaggtggcg aggtcaaggt tgaaaataaa gaaactctca
    16741 aggtcaagca tgagggggga gtggttattg aaggtgcttc tggtctccta gtgcggattg
    16801 ctaagtgttg taaccccgtg cctggtgacg atattgttgg ctacattacc aagggtcgtg
    16861 gtgtggctat tcaccgtgtg gactgtatga acctgcgtgc ccaagaaaac tacgagcaac
    16921 gtctccttga tgtggaatgg gaagaccagt actctagctc aaataaggag tatatggccc
    16981 atatcgatat ctacggtctc aaccgtacag gactgttgaa cgatgtactg caagttcttt
    17041 caaatacaac caagaatatt tcaacggtca atgcccaacc aaccaaggat atgaagtttg
    17101 ctaatatcca tgtgtccttc ggtattgcca acctctctac actgaccacg gttgtcgata
    17161 aaattaagag tgtgccagaa gtttactctg tcaaacggac caacggctag ttgtcctagc
    17221 tcttactaga aaggctatta tgaaaatcat tatccaacgg gttaaaaaag cccaagtgag
    17281 tatagaaggc cagattcagg gaaaaatcaa tcagggactt ttattgctgg ttggtgttgg
    17341 accagaggac caagaggaag atttggacta tgctgtgaga aaactggtca atatgcggat
    17401 tttttcagac gcagaaggca agatgaacct gtctgtcaaa gatattgaag gagaaatcct
    17461 ctctatttct cagtttaccc tctttgcgga tactaagaaa ggcaatcgtc cagcctttac
    17521 aggggcagct aaacttgata tggcatcaga cttctatgat gctttcaatc aaaaattagc
    17581 gcaagaagtg cccgttcaga caggcatctt tggagcagat atgcaggttg agctggttaa
    17641 taacggacct gttaccatta tcctagatac taaaaagaga taagaaagac caagcccagt
    17701 cggcttggtc tttctcatct atcataaaat actccaaaaa gaaatcggtt cttgatatgc
    17761 ttgggggaag tctcttttca ggctttggca gatgcgatag gaagggatga gatgtcctag
    17821 gatgaggaga gttccctgaa ggaaaagtgg aatatcactt aaagacacca aggagagaat
    17881 catcaggcta tcccatagga gaatttgtaa agcaaaacgc cagaatctcg gtctaatctg
    17941 ggaatagagt taactaaagt ggtcacaaag ttggtttgaa agataggtca atagcacagg
    18001 atgaaagaaa atgagccaac cgctataaat caaaatccag tcccaagtaa gccccccttt
    18061 taaatgtcaa aaatgctagc atgattccat caatgacaag gagttgaatg gttttgatga
    18121 agatgatttt tttcatgcta aaacctcctt ttccttagag acactcccat aaagagatgt
    18181 gtttgtcgta aaagtctgga tagttttctc ttaggtagtc agctgtcata taataaaaag
    18241 tagaatggca agcagtgatg attggcataa gagatgaaaa acgctgagaa ctaatgaagg
    18301 ctaagagaac aaaaaataga aaatcaatgg tgagaacccc taaatagtag aagcgaatct
    18361 ttttattgat ttgaggataa atctcagcga attgatgttt gagtcggacg atcaagagaa
    18421 atagcaggag tccttgagca aggaagaaaa ttaaaccaga gagcaagagc cactcaaaag
    18481 atgtctcgag tctaatgata aaaaatgcaa atagtagcaa atcaataact gcaattgcta
    18541 taaaatggat tctatagagt tttttcatga caagacctcc ctcttttatc taacttcatt
    18601 ctactccaaa agaatgggag ttacaactaa aatgataaaa atagcagaag ggagattctc
    18661 ttaagttggc tagtattctt tatttgagtt tccttctatt atctaacttc ttcatcattc
    18721 cagacaaata aagctccgat tgcattgagg atataaaaga tgtatttacc gatattggcg
    18781 aagtttcctt gaataccagc ttttgtcagc tgaacgaaat tgtaaatcaa ccaaaagccc
    18841 cactgagttg ttagttttaa tgcattcaaa gcattggcaa tgagggatag tgcaaaggca
    18901 atagttgtta cgtaggcaag gagattcatc ttgccctcat atccgatata gttggtcaca
    18961 aaggcaaaga ggaaggcgat gatggaaatg atgatgaccg tcaattttac ctgtttttgg
    19021 ctcatttggt tgggtctgcc ttcttgcgaa gctttccatt tctttatagc aaaggtataa
    19081 atgaggaagg tgacgggata ggtaatgatg gccgccttat ttccaaggat ataatcaata
    19141 gcaccggaca aaatggtatt aacaatacta aagtaatttc cccatttgct taatttcccc
    19201 gtgaaacgag tggacaacat ggaaatccca acgttggtta cggaaatcaa tccaaagggt
    19261 acaagagctg tccatggtcc ccagtctaca aatttatcga ggcgtgagtt gaggtaacca
    19321 gatgcaatcg caatcccaac gaccaaagca accccgaaga ggtcaaacca tttagatgta
    19381 gcaaaaattt ttagtgattt tttcataggt taaactacct ttcttttttt tttcaaatat
    19441 tctaccacca aatgaaagta aaataaaatg atagaaataa aaccctgaaa ataaaacttt
    19501 cagggttggt aggggacttg agaaattagt tgattttctc gacatagagt tgttttgcaa
    19561 tgtccatatt cacttgtaaa tcctcgtcgt tactgaggat agtgaaggta ttgctgaagc
    19621 catcaaactg cttgacttgg agctggtcac cgatgtgaag tgagtgcttg tccagataat
    19681 ggagaatgtc aaaattatcg tgcacccgag tcaggcggta ggcgccagct tccttgatat
    19741 cagctagtgg gaggttattg atttcaacga ggagttctcc cttggcagga atagttcctc
    19801 cgtgggggca ggttttaggg aaacctagca gtttatctag tctttccacg aacaggtcag
    19861 agacagtgtg ttccaagacc tcagcttcct cgtgaatctg gtcacttgta tagtctaaat
    19921 gatgaactag aaaaacttca atcaagcggt gcttacgata gagctcagag accagtttga
    19981 gaccgaggtc agtcagtaga tagccacatt ccttgtcctt taggatgaga ttttcacttt
    20041 tcattcgttt gatcatttca gttacggcag ggggagagac ttgcatgcga gccgcaattt
    20101 ccttgttggt aatcttatgc aggtctatgc caatttcata aatacatttt agatagtctt
    20161 ctttgtttgg ggtcattcgt ttcctcttgt ctaatatctt tatctagtat atcaaaaaaa
    20221 gctagatttc tctagctgtg actttttatg ttatacttat tgcaagagaa aaaacgagga
    20281 gatggatatg acgaaaatag ctcttctttc agatattcat ggaaatacca ccgccttgga
    20341 ggctgttttg gcagatgctc agcagctagg agtggatgaa tactggcttt tgggagatat
    20401 tctcatgcca gggacaggac gtagaaggat tttggacttg ttggatcaac taccgattac
    20461 ggctagagtt ttgggaaact gggaagacag tctttggcat ggtgtccgta aggaattgga
    20521 cagtactcgc cccagtcaac gctatctctt gcgccagtgc cagtatgttt tagaggaaat
    20581 ttccctagaa gaaattgaag tgctccacaa tcaacctctt caaattcatc gtcagtttgg
    20641 ggatttgacg gtgggaatta gccatcatct gcctgataag aactgggggc gagagttgat
    20701 tcatactggc aaacaagagg agtttgaccg cttggtgact catcctccct gtgatattgc
    20761 tgtttatgga catattcacc agcagttgct tcgttacggg actggtgggc aattgattgt
    20821 caatccgggt tcgattggcc aacctttctt tttggacgct cagctacgga aggacttgcg
    20881 ggcccagtat atgattttgg agtttgatga caagggcctg gtagatatgg acttccgacg
    20941 ggtagattac gatgtggcag ctgaattgca gctggctaaa gacctgagac ttccctattt
    21001 tgaggtttac tatgaaagtc tggtcaatgg gatccaccat actcatcatc aggaattttt
    21061 gagagaattg gctcagaaag agggctgcga tcgggagtta gacgactggt tgaaaagtgg
    21121 taacgattga cattacaact aaaaagggta taataataga aaaagaagag tagaggcagg
    21181 gtagcctcgt aaaaaggaga agaggatgca aattccaagt agatttacca ttgcgactca
    21241 tatgctgata atcattgccc tcgaggggaa ggaaagcaag gtgaccagtg attttctggc
    21301 tgctagtgtc ggggtcaatc ctgtcattat cagaaagatc ttgtcccagt tgaagaaggc
    21361 agagctgatt tcagtagcgc gtggaacggg cggaacagag attgtcaagg accttaagga
    21421 tattagtctt ttagatgttt atcaggcggt cgaatgtctt ggtaagacag gtcaactctt
    21481 cagtttccat gacaatccga atccaaattg ccctgtagga gctcatattc atgatgtttt
    21541 ggatcaaaaa ttggagagaa ttcagttgac tatggaggca gaacttggtc aaaccagtct
    21601 agaaaaagtc gtggccgatg cagagagtca gatgaaggat taagagggat aaatgccctc
    21661 ttttttcttt ggataattat gataaaatgt agctattaaa ggagtaagaa atgtatctcg
    21721 ttataggaat tgtattagcc tttatagtgt cattttggaa ggataataga agtttgtgga
    21781 atccagtatt atttttatta tccctcattt caagttattt ttatctatcc tacctttttt
    21841 ataaaaatgg atacgagaat gttcagttag ctttttatgt atttgccttt gtcttacttc
    21901 cttttttgct ttttctaagt ggcatctttt taatctataa tggggtcatt ttgttgaagc
    21961 gagagggacg ttccaagccc cattatctct caatgctctt tgatttttat tgactattag
    22021 attctattta aaaagactta gaatgcacat gaaagtatgt attctaggtc ttttgttttg
    22081 tatacattta attgtcaaga gtattatcta tttttccatg cctggtaacg agtatcaatc
    22141 aataactggg taaggcgacc caaggtttct ctttcttctg gagtgaggga ttgagcttgg
    22201 acaaagagat gatgaatgta ttcaagcgcc tttaaggaag ccaagtcatt gatagagcta
    22261 ataccagcct caagaatagt gccaaagaag aggtcgaagt agagctgaag ttcttcgtca
    22321 gggactgtgg ccacccattc tttaaaggtt gtgtctactt gctggctatc actgttggtc
    22381 ttatccagtt ggacgaagtg cttgtcctca atctgccaac taaaggtatc gtgctgggcg
    22441 atgccaccca gggcagtact ctgaacgatg atttggtgag caggaatttc cagcatcata
    22501 ccgataatgg aaccttgtgg aatgaatatc ttgcttctat ccattatcct ttgataaccc
    22561 gcagtctgtg tcaattcttg atggagacca ggtgcatcaa atgtataaac tgctgtgatc
    22621 tgattttgca aactttgctc aatttggcta gcagcataga tagcgagatt tcctcccttg
    22681 gaatgcccag ctagaataac cttttgctta ggatgatggg caaaaaagtt ctttaaatag
    22741 cgaagggcgt gcttttgagc aggaatttcc ttcatatagg tcaggtggaa atcttccttc
    22801 cagccaatga tactgtcatc tgtcccacga aagacaatca gataggtatc gaggctgaca
    22861 cgataagtca tagccgcaaa ttgcttttgc agttcagggt cgatgtcgtt gataaaatgg
    22921 gagagtttgc aatttttgaa gcgcttgtgt tgagccaatt catctaataa ttgaaggcga
    22981 tttttgctag taagcatggt gggatctctt ggaacctgag gtgctagatc taaaagacgt
    23041 tgaggaagtg tggagaccag attatcaaag gagaggtagg tgatttctat taaggttaga
    23101 atgtctaact cattcaaggg aaggtcgtaa taagaatcat atgcgacatc tttcagatag
    23161 tcaaaaatat tggccataag agctcctttc tttttattta tcttagcaaa tttccctcaa
    23221 attagctagt agcattgcct gtttgtactg gctaaaaaca ggctatttca aattcagttt
    23281 cagaccatct ggcatggaaa aatctgttat aataatagaa aaggagaagc gcatgcacaa
    23341 gattttatta atagaagatg atcaggtcat tcgtcaacag gtcgggaaaa tgctctctga
    23401 atggggattt gaagtggtcc tggtagaaga ctttatggaa gttttgagtc tatttgttca
    23461 gtcggaacct catctggtcc tcatggatat tggtttgccc ttgtttaatg gttatcactg
    23521 gtgtcaggaa atccgcaaga tttccaaggt acctatcatg tttctttctt cgagagacca
    23581 ggctatggat attgtcatgg caatcaatat gggggcggat gactttgtga ccaagccttt
    23641 tgaccagcag gttcttttag ctaaggttca gggcttgttg cgtcgttcct atgagtttgg
    23701 gcgtgatgag agtttgctgg aatatgctgg tgttatcctc aataccaaat ccatggattt
    23761 acattatcaa gggcaagtct tgaatttgac caagaatgaa ttccagattt tacgcgtgtt
    23821 atttgagcat gcaggcaaca tcgtagcacg tgacgacctg atgcgggaac tttggaacag
    23881 tgactttttc attgatgata ataccctctc tgtcaatgtg gctcgtttgc gtaaaaagtt
    23941 ggaggagcag ggattggtag gatttatcga gaccaagaaa ggaatagggt acggattgaa
    24001 gcatgcttga ttggaaacaa ttttttctag cctatctgcg ctcccgtagt cgtcttttta
    24061 tctatctgct ttctttggca tttcttgtct tactctttca gtttttattt gccagtctag
    24121 gaatttactt cctctacttt ttcttcttgt gttgctttgt aaccatctta tttttcactt
    24181 gggacatatt ggtggaaacg caggtctatc gccaggaact tctctatgga gagagggaag
    24241 ccaagtctcc tttggaaata gctttagcag aaaaattaga agcgcgtgag atggaactct
    24301 atcagcagag gtcaaaagca gaaagaaaac tgacggattt gctggattac tataccttgt
    24361 gggtccatca gataaagacc cccattgcag ccagtcaact cttagttgca gaagtggtcg
    24421 accgccaact gaagcagcag ctagaacagg aaattttcaa aatcgactcc tataccaacc
    24481 tagttttaca gtacctgcgt ttagaaagtt tccatgatga tttggtctta aagcaggttc
    24541 aaattgagga cttggtcaag gaaataattc gtaaatatgc tcttttcttt attcaaaaag
    24601 gcttaaatgt caatctacat gaccttgata aagaaatcgt gacggataaa aagtggctgc
    24661 tagtggttat tgagcaaatc atctcaaaca gtctcaagta caccaaggaa ggtggtctgg
    24721 agatttatat ggatgaccaa gagctttgta tcaaagatac gggaatcggg ataaaaaaca
    24781 gtgatgtcct ccgagtattt gaacgtggct tttcaggata caatggccgt ttgacccagc
    24841 agtcctctgg acttggcctt tatctatcta agaaaatttc tgaagaactg gggcaccaga
    24901 ttcgtatcga gtctgaggtc ggaaaaggaa cgacagtgcg gattcagttt gctcaagtga
    24961 acttagtcct tgagtaaaaa tagatgagaa aaagcctcca gattggaggc ttttatgcta
    25021 gacacttatt tctcaacgcg tgatttgttg gcgatatcag ctaggatagc ttgaacaaaa
    25081 ttatcaactg agacagtttg tgtttctttt tggccgtagc gacgaacgtt gactgtttcg
    25141 tcttccattt ctttgtctcc aacaattaat tggtaaggaa tcttgctggt ttgtgaagca
    25201 cggatcttga actgcatttt ttcattgcgc tcatctacgt ctgcacggac accgcggtca
    25261 cggagtttct tggccacttc ccaagcgtag tccacgtgtt tttcgttaga tactgggatg
    25321 agggttactt ggtgtggtgc cagccatgtt gggaaggccc ccttgtagtt ctcaatcaag
    25381 atagctgtga agcgttccat agttgagata accccacggt ggatcatgac tggacggtga
    25441 tcttcgccat cagctccgat gtatttgagg tcgaagcgtt ctggcaacaa gaaatcaagt
    25501 tggatagtag aaagggtttc ttcttttcca agggcagttt taatctggat atccaatttt
    25561 ggtccgtaga aggctgcttc accttcggct tcaaagtagt ccacgcccat ttcatcaaga
    25621 gctgcacgaa gcatagtttg ggcattttcc cacatctcat cgttatcaaa gtacttatga
    25681 gtatcttgag ggtcacgaag agagaggcgg aagcggtagt cagtcaagtt gaagtcttca
    25741 taaacatcga taatcaactg aagggcacgt tggaattctt cttggatttg ttctggagta
    25801 acgaataggt gaccgtcgtt gagtgacatt tcacgtacac gttgaaggcc agtgagggca
    25861 ccagattttt cgtaacggtg catcataccg atttcagcga tacggattgg caattcacgg
    25921 taagagtgaa catggtgttt aaaaacttgg atgtggtgcg gacagttcat tggacgaagg
    25981 acaaattctt ccccgtcacc catgtccatg gttgggaaca tgtcttcttg gtaatgatcc
    26041 cagtgaccag aagtcttgta aagctcaaca gaagcaagtg gtggagtgta gacgtgttgg
    26101 tagccagaag ccaactcttt gtttacgatg tagcgttcca attcacgacg gatagtcgca
    26161 ccatttggca accagaatgg caaaccttgt cccacttctt gtgaaatcat aaagaggtca
    26221 agctctttac caagtttacg gtggtcacgt tccttagctt cttcacgcat ttgaaggtag
    26281 tttttcaagt ctttcttgtc aaaccaagct gtaccgtaga tacgttgcat catagcgttg
    26341 tcgctgtttc cacgccagta cgcaccagct acatggagaa ggtggaagat ttggatacga
    26401 cctgttgatg gaacgtgagg tccacggcag aggtctacat attcaccctg acgatagata
    26461 gtcaaaccgc cttcgtcttc tgagtgttct tcaatcaatt ccaacttgta agggtcattt
    26521 ttgaagattt cacgtgcctc gtctttagtc acttcttcac gaatagatgg gaagttttct
    26581 ttgacgattt tttgcatttc ttcttcgata cgaggaaggt cttcgttaga gatttgacca
    26641 gctgtgttgt cagtatcgta gtagaaacca tcttcgatgg ctggaccaac tcccaagtga
    26701 atgtctggga aaagacgacg agctgcttgg gcgaacaagt gagctgctga gtgacgcaag
    26761 attggaaggg catcttcgtg atcaggtgtc acaatttcga tgcttccatc ttcagtgata
    26821 gcgcgagtag tgtcgatgag tttgccgttg aatttaccag ccaaggcttt tttagctagg
    26881 gaattgctga tagattgggc aatttcaaaa gttgttacgc cagattcgaa ttcacgaaca
    26941 gcgccatctg ggaaagtaat gttaatcatg atgttctcct tttttattat ttcatagttt
    27001 ctaagcattg attttttatc agcagactac ttccgagtcc taacgttcaa ttgcttttct
    27061 ttatcagaga ggaagttttc catttccgtc agaatgtcta tatccaaacg ttgagaaagt
    27121 tctaatagcc accagatatt ttctgaaagt ttttgttcca gtgtgtaggg tgtttcatca
    27181 tagtagcgtc cttgctttgt catcaccagt cattggaaat ttccaatatc attagataaa
    27241 gccaagaggt cttcttctac cgtccacttg aaatcatgat gcttaacttc cagttcgtga
    27301 taagcttgtc ggattgccca actgcgctcc actaattctt gcaactccat aattagtatc
    27361 ctaataaaaa aatgcgacat cctcgaaagg acgtcgcaac gtggttccac cttcatttat
    27421 gtacctcaaa agagagggac acctctgatc ggctctaacg tggccaccgt tttatgtttt
    27481 cataaaaaac tcaagagtag tatcagttta gacttcctat gcgtttccag caaccacgca
    27541 ctctctagta gaaagggact aagtgacttg tctctatgga ttattatagc atgattgtga
    27601 gatttttcaa ggattttgtg aaagtttttt gtttttcatt ttttgtagaa tatgcttgat
    27661 gctaatacca gaatccatgc cgaccagagc aactgtttca tagattagca agtaaattag
    27721 tataaactca ccaaaggtta tgatagtaaa gtaaaagagc agtccgttac caactaacca
    27781 tcaaagtgag aaacggaaac ggtagctata gagtaacgat ataatcaaga ttaccagagg
    27841 tgtaaagaag agaagattgt ttatatagag ttccttgagt gtaagggggt cagaaacaac
    27901 tagtaagaac aactcataaa gtggccaata aaagaataat atgaccagat agtaggggag
    27961 atgggaatag aatctacgca tgataatcac ctcgttttaa aaaaacagac aacttagatc
    28021 tcttgctatg attattatag catgtttaaa acaagaaagt aaatttgttg acaaagaaga
    28081 tttttctttt cactagaatc atagttagtt ttcttggtag aaatattttg ataataatta
    28141 agcaagacta ttgacattga ttattaagag tgtcacaatt attgtaacta aaataattac
    28201 aacaagagag gtataaaaaa tgaaactagc agttattgca gcaaatggac aagcggggaa
    28261 agcaattgtt gaagaagcag tcaaacgagg acatgaagta acggctattg ttcgttctga
    28321 aaacaaaagt caagctgagt ctattattaa aaaagattta tttgagttga caaaagatga
    28381 tcttactgga tttgatgctg ttatttcagc gtttggtgct tatacaccag atacgctacc
    28441 gctccacagc aaatcaatcg aactatttaa tcagcttctt gctggaacac agacacgttt
    28501 tctagttgta gggggagcag gaagtcttta tatagatgaa acaaaaacga cacgactttt
    28561 agatacgtct gattttcctg aagaatttaa gtcactagca aaagatcaag cggatgaatt
    28621 ggatcttctt cgtacaaaaa ataatctcaa ctggactttt gtcagtcctg ctgtagattt
    28681 tattcccgat ggtgaaaaaa caggaaacta cattctagca ggagaaattt ttactactaa
    28741 tgaaaaagga ataagccaga ttagttatgc agattatgct attggattgg tagatgaact
    28801 tgaaaaaggt catcatataa aagaacgtat ctctttactt gaaaaataat aactatgaga
    28861 gtattaatgt ttgacagaaa atttaaatct tggtaaaata gggattgtcg taaagacaaa
    28921 taacttcttc ttggttacag gcatgccaac ctgtcactcg gatgaagcca aataaaaagg
    28981 agaaacatca tggcaatctc aaaagagaaa aaaaatgaaa tcattgcaca atatgcacgt
    29041 cacgaaggtg atacaggttc agtagaggtt caagttgctg tccttacttg ggaaatcaac
    29101 caccttaacg aacacatcaa acaacacaaa aaagaccacg ctacttaccg tggattgatg
    29161 aaaaaaatcg gtcgccgtcg taacttgctt gcatacttgc gtaaaaacga cgttaaccgt
    29221 taccgtgagt tgatcaactc tctaggactt cgtcgctaat tcaagataca aatgctgtca
    29281 aaagcacaaa gcaaaaatag gaaaattgac gaagaaactt cagtttctag gagattttat
    29341 cttttttgcc aagtgcttag gccgtgttca attgagcata tcttgataat gaagctactc
    29401 taaattgggt agcttttttg cgttgtcacc ttacctcgat atactcaagt ataatctttg
    29461 gttacggttc ctagcactgt aaggtaaaat aaaccagctt ttctcccttc ggggagattt
    29521 tttttgtttc actgaaagtt tcgtacgatc ttcgcctcgt cgcctagtct ataaacgatt
    29581 tatctagcaa gaatcatgat gctaagggcg tcaaaaatcc gtatgaaaat agggaaatga
    29641 cacagtgttc gatgagcaca aggagtttca tctttttcac taggatttta gcccgggctc
    29701 aaatcagctc tctgacttca gagggctttt ttattgaggt tttatcggta acaattttgg
    29761 agactacaaa aacctcaaac ggtatcagct aattacacca taaaggtgcg cagttactcg
    29821 gcttttcaag ccgagtagct gtatgcaagc cccctagaag agcccactct ttacaaagta
    29881 aagtatagta tgttatactt tacatggaag tagtcactga attccagtta gaaattactt
    29941 tgtaactacg ttttgaggag gagtaaaatg ctttcctacg ttcgacatta cccactagcg
    30001 atagctaaat taatgtgtct gtgctctcct aaaatctgct gatttattac tgactaatac
    30061 aggaggtttt ttttatggga cagacaatca tatctgctat tggtgtttat atttccacca
    30121 gtatcgatta tttaattatt ttaattattt tatttgcaca gctatcacag aataaacaga
    30181 aatggcatat ttatgcgggg caatatctag gcacaggctt acttgtaggg gcgagtttag
    30241 ttgctgctta tgtcgttaat ttcgtgcctg aagaatggat ggttggattg cttggtttaa
    30301 tccctatcta tttagggatt cgctttgcaa ttgttggaga agatgcggaa gaagaagagg
    30361 aagaaattat tgaaagatta gaacaaagca aggcaaatca actgttttgg acagttacat
    30421 tgctgacaat tgcgtctggc ggagataatt taggtatcta tataccttat tttgcttcgt
    30481 tagattggtc acagaccctc gtggccttgc ttgtgtttgt aatcggcata attatctttt
    30541 gcgagattag tagggtgtta tcctctattc cgttaatatt cgagacaatt gaaaaatacg
    30601 agcgaatcat tgtgccctta gtattcattc tacttggact atacatcatg tatgaaaatg
    30661 gcacgataga gacttttctg atcgtgtaga tttttttgtt tcactaggat tttagcccga
    30721 gctcaaatca gctctctgat tttcagaggg ctttttcatt gagtataaat ggacaatctt
    30781 aaagttactc tattgtagag tggcttttga tttgattagg agattcttat aaatatagta
    30841 aaatgaaata agaataggac aaatcgatca ggacagtcaa atcgatttct aaaaatgttt
    30901 tagaagtaga ggtgtactat tctagttcca atctactata taaatgaaaa ccttagctgt
    30961 ttggccaagg ttcatttctt ctatgcaagt tcttctcttt tcttatctgg gttccagatg
    31021 aagcttgcga taaagctaaa gatgatggtt aggatagcga ggataatagc aaggatgagg
    31081 gcagggatgc ggataaacca ccagagtgga tttggttttt tatcattgtg ccattgtttc
    31141 gtttcttcgt ccagacgttg gaattctgtt tgaatacgat tggcgactgt ttcaatgcct
    31201 tcatcattca ttttcttgat atctgagata tcgattggat ttccaaagtt catatcgaca
    31261 cgttcacggc taatcaagcc cttcaaagtc atgggaccgg tgtaggtaac cggcatgata
    31321 cggaccttgg ccattttggc aatcagtgct gcgcccccct tgacatcgtt tgagtggcgg
    31381 ctaccacttg gaaacatgat gagagagcgg tcactttttt tgagaacgtt gataggatat
    31441 ttgatggctg aggcgctggg attttcacgg tcgatgggaa aggcgccaca catacgaatc
    31501 caccaaccaa agatacggtt ggtaaagagt tctttttttg ccataaagat gaactgtttt
    31561 ggcttggtcg caaaggccat ataaacagga tcccaccagg tacggtgagg cgcaactaaa
    31621 atataatttt catcttgatt aggaatttta tcagtattat gatagtgagc attgccattg
    31681 atggaccata agagcaatac aactaatcca cgcaaataag tataaaacat gcgatctcct
    31741 tcgattgttt tcttgttatt attatacctt atcaaaggag ggctggcaaa cttttccctt
    31801 gactagatac atatttagga tgaaattaga attctgttaa aaaaaatgat ataatagaat
    31861 ttatggataa aaataagatt atgggattaa cccaaagaga agtcaaggaa agacaggctg
    31921 agggtttggt caatgacttt accgcatcag ccagtaccag cacttggcaa atcgttaaac
    31981 gaaatgtctt tacccttttt aacgctttga actttgccat tgctttggct cttgcctttg
    32041 tgcaggcttg gagcaatctg gtcttctttg ctgttatctg ctttaacgct ttttctggga
    32101 ttgtgaccga gctacgagcc aaacacatgg tggacaagct caatctcatg accaaggaaa
    32161 aggtcaaaac catccgtgat ggtcaggaag ttgctcttaa tcctgaagaa ttagtgctag
    32221 gagatgtcat tcgtttgtct gcaggagagc agattcctag tgatgccttg gttttggaag
    32281 gctttgcgga agtcaatgaa gccatgttaa cgggagaaag tgatttggtg caaaaggaag
    32341 ttgacggctt acttttgtca ggaagtttcc tagccagtgg gtcagtttta tctcaagttc
    32401 accatgtcgg agcagacaac tatgctgcca aactcatgct tgaggctaag accgttaaac
    32461 ccatcaactc ccgtatcatg aaatcgctgg acaagttggc tggttttact gggaagatta
    32521 tcattccctt tggtctggct ctcttgctgg aagccttgct tttaaaaggc ctgcctctca
    32581 agtcatccgt tgtaaactcg tcgacagctc ttttgggaat gttgcctaag ggaattgccc
    32641 ttttgaccat tacttcgctt ttgactgcag tgattaagct aggtttgaaa aaggtcttgg
    32701 tgcaggagat gtactctgtt gagaccttgg cgcgcgtgga tatgctctgt ctggacaaga
    32761 cgggcaccat cacccaagga aagatgcagg tggaggctgt tcttccactg acggaaactt
    32821 acggtgaaga ggctattgcc agcatcttga ctagctacat ggcccatagt gaggataaaa
    32881 atccaacagc tcaagccatt cgccagagat tccaaggtca agtagtctat cctatgctct
    32941 ctaatcttcc cttctccagc gaccgcaagt ggggagccat ggagttagaa ggtttgggaa
    33001 tagttttctt aggggcacct gagatgttgc tggattctga ggtcccagaa gccagagagg
    33061 ccttggagag aggttcacgt gtcttggtct tagctctcag tcaggagaaa ttagaccatc
    33121 acaaaccaca gaaaccatct gatattcagg ctctagcctt gctggaaatc ttggatccta
    33181 ttcgagaggg agcggcagag acgctgaact atctccgttc tcaggaagtg gggctcaaga
    33241 ttatctctgg tgacaatcca gttacggtat ccagcattgc ccagaaggct ggttttgcgg
    33301 actatcacag ctatgtcgat tgttcaaaaa tcacggatga ggaattgatt gctctggcgg
    33361 aggagacagc gattttcgga cgtgtttccc ctcatcaaaa gaaactcatt atccaaacgc
    33421 tgaaaaaagc gggtcataca acggctatga caggggacgg ggttaatgat atcttggccc
    33481 ttcgtgaggc ggattgttct atcgtaatgg cggagggaga cccggcaacc cgtcagattg
    33541 ccaacctggt tctcttgaac tcagacttta atgatgttcc tgagattctt tttgaaggtc
    33601 gtcgtgtggt caataacatt gcccacatcg ctccgatttt cttgataaag accatctact
    33661 cattcttgct cgcagttatc tgtatcgcca gtgctttact aggtcggtct gaatggatct
    33721 tgattttccc cttcattcca atccagatta ccatgattga ccagtttgtg gaaggtttcc
    33781 caccattcgt tctgactttt gagcgaaata tcaaacctgt tgagccaaat ttcctcagaa
    33841 aatccatgct tcgtgcccta ccaagcgctc tcatggtcgt gtttagcgtc ctgtttgtga
    33901 aaatatttgg gagtagccaa ggttggtctg agttagaaat ctcaactctc ctctattatc
    33961 tcttggggtc aattggtttc ttatccgtat ttagagcctg catgccattt accctatggc
    34021 gagtcctatt gattgtctgg tcagtaggag gcttcctagc cacagctctc ttcccaagaa
    34081 ttcaaaaact gcttgaaatt gcaaccttaa caggacaaac attacctgtt tatggtgtca
    34141 tgatgttggt ctttaccgtg attttcatcc tgaccagtcg ctatcaagcc agaaaataaa
    34201 gaaaggctgc aatctgtgga ttgcagtttt ttaggtacaa gattgccagt cgaaatgtgg
    34261 tataataaga ggtaatagag ttttggaaag tgagagaaga tgatttcaaa gagattagaa
    34321 ttggtagctt cctttgtgtc acagggggct attttactag atgtgggaag tgaccatgct
    34381 tatctgccta tcgagttggt tgagagaggc caaatcaaaa gcgctattgc aggtgaggtg
    34441 gtggaaggtc cctatcagtc tgcggttaaa aatgttgagg ctcacggcct aaaggagaaa
    34501 atccaagtcc gtttagccaa tggcttggca gcttttgaag agactgacca agtgtctgtc
    34561 attaccattg ctggcatggg tggtcgtttg attgctagga ttttagaaga aggtttgggg
    34621 aagttagcta atgtagagcg tttgatcctc cagcccaata atcgtgaaga cgacttgcgt
    34681 atctggctac aggatcatgg attccagatt gtagcagaaa gcatcttaga agaagctgga
    34741 aagttttatg agattttggt ggtggaagca ggacaaatga agctatcagc cagtgatgtt
    34801 cgctttggtc ccttcttgtc caaagaagtc agtccagtat ttgtccaaaa atggcaaaaa
    34861 gaagctgaga agctagagtt cgccctcgga caaatcccag aaaaaaatct ggaagaacgt
    34921 caagttctag tagataagat tcaagctatc aaggaggtgc tccatgttag caagtgaagt
    34981 gatccaagct tatgaagcct tttgccctca ggaattttct atggagggag acagccgtgg
    35041 tctgcaaatt ggcactttag acaagggtat ccaaagggtc atggttgccc tcgatattcg
    35101 tgaagagaca gtggcagagg ccattgaaaa gggtgtggac ttgattatcg tcaagcacgc
    35161 gcctatcttt cgtcctatca aggacttgct tgccagccgt ccgcaaaatc agatttacat
    35221 cgacctgatt aagcatgata tcgcagttta tgtcagccat accaatattg atatcgttga
    35281 aaatgggctc aatgactggt tttgtcagat gctaggaatc gaggagacga cttatctgca
    35341 ggaaacaggt ccagaacgtg gaattggacg tattgggaat attcagcctc agacattttg
    35401 ggaattggcc caacaggtca agcaagtctt tgacctagat agccttcgaa tggtgcatta
    35461 tcaagaggat gatttgcaga agcctatttc aagagtagca atttgtggtg gaagcggaca
    35521 gtctttctat aaggatgctt tggcaaaggg ggcagatgtc tatatcactg gtgatatcta
    35581 ctaccatact gctcaggata tgctgtctga tggcttgtta gcattggatc caggtcacta
    35641 tatcgaagtg ctttttgtgg aaaaaatcgc aacactcctt actcaatgga aagagaaaaa
    35701 aggctgggaa ctagagattt tacctagtca agcatcgacc aatcctttcc gtcatatcta
    35761 gttagaaagt gaagacaatg aaaaaagttg ccattattgg agcaggaatt gtgggagcaa
    35821 cagctgccta ctacctctcg agagaaagtg acctagaggt gaccgttttt gaccatgagc
    35881 aaggtcaagc caccaaggct gcagcaggaa ttatcagtcc ttggttttcc aaacgccgta
    35941 ataaagcctg gtacaagatg gcgcgcttgg gggctgattt ttatgtggat ttattagctg
    36001 atttagagaa atcaggacaa aaaatcgact tttaccagcg ttcgggagtc tttctcttga
    36061 aaaaggatga atccaagttg gaagaacttt atcaactggc cctccagcgc agagaagaat
    36121 ctcccttgat agggcaatta gccattctgg accaagcctc agctaatgaa ttattccctg
    36181 gtttgcaggg atttgaccgc ctgctctatg cttctggtgg agcgagagta gatggccacc
    36241 tcttagtgac tcgtttgctg gaagccagtc aggtcaagct ggtcaaagaa aaagtgactc
    36301 tgacaccgtt agcatcaggc taccagattg gtgaagagga gtttgagcag gttattttgg
    36361 cgacgggagc ttggttgggg gacatgttag aacccttggg ttatgaagta gatgttcgtc
    36421 ctcaaaaagg acaactacga gattatcagc tggtccaaga catggaagct taccctgttg
    36481 tcatgccaga aggggagtgg gatttgattc cttttgcagg tgggaaattg tccttaggcg
    36541 ctacccacga aaatgacatg ggatttgatt tgacggtaga tgaaaccttg ctccaacaaa
    36601 tggaggaggc caccttgact cactatctga ttttggctga agctacttca aaatctgagc
    36661 gtgtgggaat ccgtgcctat accagtgatt tctctccctt ctttgggcag gtgccagaat
    36721 tggcaggtgt ctatgcagcc agtggactag gttcatcagg cctcacaact ggtcctatca
    36781 ttggttacca tctagcccaa ctgatccaag acaaggagtt gaccttggac cctctaaatt
    36841 acccaattga aaactatgtc aaacgagtaa aaagcgaata atactcaatg aaaatcaaag
    36901 aacaaactag gtaactagcc gcgggttact caaagcactg cttt
//
LOCUS       DBERXF010000020        36082 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.20, whole genome shotgun sequence.
ACCESSION   DBERXF010000020 DBERXF010000000
VERSION     DBERXF010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 36082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36082
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.20"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            265..1071
                     /gene="pnuC"
                     /locus_tag="ACL8JK_001100"
     CDS             265..1071
                     /gene="pnuC"
                     /locus_tag="ACL8JK_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGS1785997.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(1237..1773)
                     /gene="sczA"
                     /locus_tag="ACL8JK_001101"
     CDS             complement(1237..1773)
                     /gene="sczA"
                     /locus_tag="ACL8JK_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator SczA"
                     /protein_id="HGS1785998.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKDYETTTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLQRELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            1906..2796
                     /gene="czcD"
                     /locus_tag="ACL8JK_001102"
     CDS             1906..2796
                     /gene="czcD"
                     /locus_tag="ACL8JK_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter
                     CzcD"
                     /protein_id="HGS1785999.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            3040..3393
                     /gene="nmlR"
                     /locus_tag="ACL8JK_001103"
     CDS             3040..3393
                     /gene="nmlR"
                     /locus_tag="ACL8JK_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HGS1786000.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            3394..4431
                     /locus_tag="ACL8JK_001104"
     CDS             3394..4431
                     /locus_tag="ACL8JK_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HGS1786001.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(4477..5484)
                     /gene="galR"
                     /locus_tag="ACL8JK_001105"
     CDS             complement(4477..5484)
                     /gene="galR"
                     /locus_tag="ACL8JK_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HGS1786002.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAI
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQAKGIYHDELIFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            5648..6826
                     /locus_tag="ACL8JK_001106"
     CDS             5648..6826
                     /locus_tag="ACL8JK_001106"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGS1786003.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGSGLSSSASLEILTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            6845..8326
                     /locus_tag="ACL8JK_001107"
     CDS             6845..8326
                     /locus_tag="ACL8JK_001107"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGS1786004.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLSRVGEGVLEVETNL
                     DKLIDLKDQLVEETVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIARNIAYRVPSDYGELEITINLSKPEKDPKEIVAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVDQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKAFRFAGFEQVKAGIVKWPMSVLRLTSDSKEDLINLADKILQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            8396..8800
                     /locus_tag="ACL8JK_001108"
     CDS             8396..8800
                     /locus_tag="ACL8JK_001108"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HGS1786005.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            8981..9745
                     /locus_tag="ACL8JK_001109"
     CDS             8981..9745
                     /locus_tag="ACL8JK_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HGS1786006.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            9742..10203
                     /locus_tag="ACL8JK_001110"
     CDS             9742..10203
                     /locus_tag="ACL8JK_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HGS1786007.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(10254..11516)
                     /locus_tag="ACL8JK_001111"
     CDS             complement(10254..11516)
                     /locus_tag="ACL8JK_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGS1786008.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(11516..12097)
                     /locus_tag="ACL8JK_001112"
     CDS             complement(11516..12097)
                     /locus_tag="ACL8JK_001112"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGS1786009.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(12497..12592)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(12975..13214)
                     /locus_tag="ACL8JK_001113"
     CDS             complement(12975..13214)
                     /locus_tag="ACL8JK_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HGS1786010.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     gene            complement(13214..13357)
                     /locus_tag="ACL8JK_001114"
     CDS             complement(13214..13357)
                     /locus_tag="ACL8JK_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HGS1786011.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            complement(13369..14196)
                     /locus_tag="ACL8JK_001115"
     CDS             complement(13369..14196)
                     /locus_tag="ACL8JK_001115"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGS1786012.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            14330..14785
                     /locus_tag="ACL8JK_001116"
                     /pseudo
     CDS             14330..14785
                     /locus_tag="ACL8JK_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            14938..15234
                     /locus_tag="ACL8JK_001117"
     CDS             14938..15234
                     /locus_tag="ACL8JK_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGS1786013.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            15440..17185
                     /locus_tag="ACL8JK_001118"
     CDS             15440..17185
                     /locus_tag="ACL8JK_001118"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1786014.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQTAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            17175..18926
                     /locus_tag="ACL8JK_001119"
     CDS             17175..18926
                     /locus_tag="ACL8JK_001119"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1786015.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            19099..19791
                     /locus_tag="ACL8JK_001120"
     CDS             19099..19791
                     /locus_tag="ACL8JK_001120"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGS1786016.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            19834..21060
                     /locus_tag="ACL8JK_001121"
     CDS             19834..21060
                     /locus_tag="ACL8JK_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HGS1786017.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            22191..24350
                     /gene="pfbA"
                     /locus_tag="ACL8JK_001122"
     CDS             22191..24350
                     /gene="pfbA"
                     /locus_tag="ACL8JK_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HGS1786018.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            24334..24630
                     /locus_tag="ACL8JK_001123"
     CDS             24334..24630
                     /locus_tag="ACL8JK_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786019.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            24802..25185
                     /locus_tag="ACL8JK_001124"
     CDS             24802..25185
                     /locus_tag="ACL8JK_001124"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786020.1"
                     /translation="MLVNEMEITDHRVDNLFEKGKNEIKDPIGTNSVLNKKIILQKIR
                     KLSNQPSGYWIGSLDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELIK
                     MRFNSSAIDPIYGKKDDASIVVIDV"
     gene            25243..25884
                     /locus_tag="ACL8JK_001125"
     CDS             25243..25884
                     /locus_tag="ACL8JK_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HGS1786021.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERIELI
                     KEDLIINESVLNVDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QILQNNEILKKIISEIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELST
                     NIEKKIMNYIFEDDGNVSEVIGALDIIHHLDKIAHTTQSIYKWIMYRKYGNIN"
     gene            25897..27372
                     /gene="galT"
                     /locus_tag="ACL8JK_001126"
     CDS             25897..27372
                     /gene="galT"
                     /locus_tag="ACL8JK_001126"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGS1786022.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            27385..28364
                     /gene="galE"
                     /locus_tag="ACL8JK_001127"
                     /pseudo
     CDS             27385..28364
                     /gene="galE"
                     /locus_tag="ACL8JK_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996558.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
     gene            28574..29233
                     /locus_tag="ACL8JK_001128"
     CDS             28574..29233
                     /locus_tag="ACL8JK_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HGS1786023.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTIVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            29258..30325
                     /locus_tag="ACL8JK_001129"
     CDS             29258..30325
                     /locus_tag="ACL8JK_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS1786024.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            30428..31438
                     /locus_tag="ACL8JK_001130"
     CDS             30428..31438
                     /locus_tag="ACL8JK_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1786025.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            31450..33141
                     /locus_tag="ACL8JK_001131"
     CDS             31450..33141
                     /locus_tag="ACL8JK_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1786026.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            33144..33854
                     /locus_tag="ACL8JK_001132"
     CDS             33144..33854
                     /locus_tag="ACL8JK_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGS1786027.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            33950..34318
                     /locus_tag="ACL8JK_001133"
     CDS             33950..34318
                     /locus_tag="ACL8JK_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786028.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            34426..35427
                     /locus_tag="ACL8JK_001134"
     CDS             34426..35427
                     /locus_tag="ACL8JK_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1786029.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     misc_binding    35639..35868
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT        11308 a         5978 c         7704 g        11092 t
ORIGIN      
        1 cttttttgat gtgagaatga ctgaatgtca cttaaaatgg aaagaaagag aaaattttca
       61 tgattttcta aaattttact gtaaagacag ttgactattc ataaaatagg tgtataatat
      121 tttgtgaact acttaacaaa taagaggttt cagctcatgt cgactaaggt tagaaatctt
      181 gtgtataggc agttcattat ctaatagagc gttgcgtccg aaagtctatc cagacacggc
      241 tctttaaaaa caaaaggaga aatgatgcat acttatttgc aaaagaaaat tgaaaatatc
      301 aaaacaaccc taggtgaaat gtcaggtggt taccgtcgta tggttgcggc tatggctgat
      361 ttaggatttt caggaactat gaaggctatc tgggatgacc tctttgccca tcgtagtttt
      421 gcccagtgga tttatttgct ggttttagga agttttcctc tctggctgga gttggtttac
      481 gaacatcgta ttgttgactg gattgggatg atttgtagct tgacagggat tatctgtgta
      541 atctttgtat cggaaggtcg agcaagtaat tatctttttg gcttgattaa ctctgttatt
      601 taccttattt tggccctaca gaaaggcttt tatggtgagg tgctgacgac actttacttc
      661 acagtcatgc agccaattgg acttctagtt tggatttatc aggcacagtt taagaaggaa
      721 aagcaggagt ttgtcgcgcg taaactggac ggaaagggct ggacaaagta tctttccatt
      781 agtgtgcttt ggtggttggc ctttggcttc atttatcagt ctattggtgc caatcgtccc
      841 tatcgtgatt caatcacaga tgcaaccaat ggggtagggc aaatcctcat gacagctgtt
      901 taccgtgaac agtggatatt ctgggcggct accaatgttt tttcaatcta tctctggtgg
      961 ggagaaagcc tgcaaattca agggaaatat ctaatttatc tcattaacag tctagttggt
     1021 tggtatcaat ggagcaaggc agctaagcag aatactgatt tacttaacta ggaaaagatg
     1081 tttgaaagtg ctgttttgag atttcgatta aaacagatat agttgataat caaggattta
     1141 tagtatgaaa aagaggatcg gcgggtcctc ttttgttgtt gaaaagataa aaaactcagt
     1201 aacctagaaa taagacaact gagctttact ctatattcaa tttttaggaa tgagaaggtc
     1261 tagataaaat tggacaactt cctggtctgt gaaatcttga ccttttttga gccaccaggt
     1321 caatgtctcg ataaagttgg acatgaccaa gtgttggagg taagaagtag gcagattagg
     1381 gtgggcttct tttaaattat cagctagcac ggaatagacg tggtgctcaa gctctctctg
     1441 gagttgacgg aggaagtagt catttttgga aaatagcaga ctggtgatat ggtcttggtt
     1501 tttatgaaaa tggagaaaga ggtgggcgag gtagtcctca gttgaaatgg cttgctctct
     1561 ttcaaaaaga tgatggaaga ggtagcggca gagctgatcc agaagaagct ctttactctc
     1621 atagtgacag taaaaggtgg atcgtcccac atctgcgaga tcaatgatat cctgaacagt
     1681 agtggtctcg tagtccttag cattcaaaag ttgtataaaa gcttgataga tggctttttt
     1741 ggttttgctg atacggcggt caatgttagt catatggaca cttgaggcaa attgttcaga
     1801 actgaataaa gctgacgttt tgcttctatc ctttctttga gttttagtgg ataatgataa
     1861 tgaacaaggt gttcataaat ctattataac aaaggaatga gaaatatgaa ggcaaaatat
     1921 gctgtttggg tggctttttt cttaaatttg acttatgcca ttgttgagtt tattgcaggt
     1981 ggagtatttg gttctagcgc tgttcttgct gactctgtgc atgacttggg agatgcgatt
     2041 gcaattggaa tatcagcttt tctagaaaca atctccaatc gtgaagaaga caatcagtac
     2101 accttgggct ataagcggtt tagcctgcta ggagccttgg taacagctgt gattctcgta
     2161 acgggctctg ttctagtcat tttggaaaat gtcacgaaga ttttgcatcc gcaaccagtc
     2221 aatgatgagg ggattctctg gttaggaatt attgcgatta ctatcaatct gttagcgagt
     2281 ctggtggttg gtaagggaaa gacaaagaat gagtctattc tgagtttgca ttttctggaa
     2341 gatacgctag ggtgggtagc tgttatcctg atggcgattg ttcttcgatt tacggactgg
     2401 tatatcctag atcctctttt gtcccttgtc atttctttct ttattctttc aaaagccctt
     2461 ccacgttttt ggtctacact caagattttc ttggatgctg tgccagaagg tcttgatatc
     2521 aagcaagtaa agagtggcct ggagcgattg gacaatgtgg ccagccttaa tcagcttaat
     2581 ctctggacta tggatgcttt ggaaaaaaat gccattgtac atgtttgtct aaaagaaatg
     2641 gaacatatgg aaacttgtaa agagtctatt cgaattttcc taaaagattg tggttttcaa
     2701 aatattacca ttgaaattga tgctgaccta gaaactcacc aaacccataa gcgaaaggtg
     2761 tgtgacttgg aacggagtta tgagcatcaa cattagaaaa aagtgaaaaa tacttgggta
     2821 ctatcttatt tggaatagag taatttcttt attatttaaa tatttcaaaa attggtaaga
     2881 gaagagcatt gtataaactc cagatatatg attgttaatg ataaaaattt ttcgattaga
     2941 tacaaaatgc ttgacttgga gtcaactcaa agttatataa taagataagt gagttagaat
     3001 agcgtgaatt cagtgaatga aatgagagga ggttagcgtg tgaatattaa atctgccagt
     3061 gatttgttgg gaatttcagc ggatacgatt cggtattatg aacgggttgg tcttgtgcca
     3121 ccgattactc gtactgctac tgggattcgt gattttcaag atcaggatat cgaagcgctg
     3181 gaatttatta agtgttttcg ttcggcgggt gtctctgtag atagtttagt tgactatatg
     3241 tcgctctacc aaaagggaga tgaaacgaga gaggagaggc ttggtatttt agaagaggaa
     3301 aagcaaaaat tagaggagcg cttgtctcag ctacagacag ctttaaatcg tttaaatctc
     3361 aaaattaaac tttataagga aggaaaattt taaatgaaat cagcagtata tacaaaggca
     3421 ggtcaggttg gacttgctag cattgaacgt ccgcaaataa tagaagcgga tgatgtgatt
     3481 attcgtgtgg ttcgtgcgtg cgtttgtggt tcagatttat ggaggtaccg taatccagaa
     3541 acgaaagctg gacacaaaaa tagtggacac gaagcgattg ggattgttga agaagctggg
     3601 gaagccatta cgacggtgaa accaggtgat tttgtgattg tcccttttac acatggatgt
     3661 ggtgagtgtg atgcctgtct tgctggattt gacggttctt gcgacaatca tattggcaat
     3721 aatttggggg gtgattttca ggcagaatat attcgcttcc actatgcaaa ctgggcgctg
     3781 gttaaaatcc ctggtcaacc ttctgactat acagaaggga tgctcaagtc ccttttgact
     3841 cttgcagatg tcatgccgac aggctatcat gcggcgcgtg ttgcaaatgt tcaaaaaggg
     3901 gacaaggttg ttgttatcgg tgatggggct gttggtcaat gtgctgtcat cgcggctaag
     3961 atgcgtggag catcacaaat tatccttatg agccgtcatg aagaccgtca aaagatggct
     4021 atggagtcag gtgcgacagc tgttgttgca gaacgtggtc aagaaggaat taccaaggtg
     4081 cgtgaaatcc tcggtggagg agcagatgca gcacttgaat gtgttggtac ggaggctgct
     4141 atagaacagg cgctaggtgt tcttcataat ggagggcgta tgggctttgt aggagtccca
     4201 cactataata atcgtgctct tggttcgaca tttatgcaaa atatctctgt agcaggtggg
     4261 gcagcttctg ctacaacata cgataagcaa tttttactaa aagccgtcct tgatggtgat
     4321 atcaatccag gtcgcgtctt tacttcaagt tataaactgg aagatatcga ccaagcctat
     4381 aaagatatgg atgaacgtaa gacaattaag tctatgattg taatcgaata aaaaacgaat
     4441 aggagtttta gaactctatt cgttttttat gttatcctat tcttgattta gggtactttc
     4501 tcttaatgtc agtctggttc ccagcatggt caggctaggg attttccgac cgtggaggac
     4561 ttccttgtta agaatatcca tacctgctcg ccccatttct tcagtataaa ctgtgatgct
     4621 ggagagggga ggataaacct gcttggtcag gctggtgtcg ttaaaggaaa tgaggctgac
     4681 acggtctggt aggctgattc cagcttcttg gagcgcacga agggcaccga tggctaaact
     4741 atcgctggct gcgaaaaatg ctggtgggag ttggtctccc aagttctgaa tggcttcctt
     4801 catcaagtca tagccagact gggcagtaaa gtttccttga aagatcagtt catcatgata
     4861 gattcctttt gcttgactgt agtttctgaa attttccagc cgcttatcct caatgatttc
     4921 ttcttggtca gttgtttctt caaggcctgt tagaatcccg atacggtcca ttccttggct
     4981 gaggaaataa tcgacaacct gttttatggc agtgtaaaag tccgtaataa tgcaggtatg
     5041 tcccagggaa agtgtatcac tgtctagaaa gaccaggggt ttttggtatt cttcaaaggc
     5101 agaaatctga gctcggctaa attttccgat gcagagaatc ccaatcactt cctcgcttaa
     5161 ggtaaaagga tggtcattaa aatagcgcaa gatatcatag tccaactctt gggctctttt
     5221 ttctattcct aggcgaatct ggtagtagta gaggtcgtcc agctcccctt gttcgctgac
     5281 ccattgaata atggcaatct tttgcttggg tttatgggac tcgcctgtct tgaggtgctt
     5341 ggtgtagccc agctcttcag caacggttaa aatacggtgt ctggtttctt ctgtaacaga
     5401 taggctctgg tcgcggttga ggacgcggga tacggtcgcg atagagacag aggctagctg
     5461 tgcaatgtct tttaaggtag ccataaatcc tccttgatta ggttagtata tcatattttt
     5521 ctgcttttta ctgatagttt agtaaaattt tagtaaaaag gattgacctt gggaaatccc
     5581 ttggatacaa tagaagaaaa cgattacacg ttaaggtggc ttaacggaca gtcaaaggag
     5641 aaatcatatg acacaacatc ttactgctga aactcttcgc aaagactttc ttgctgtttt
     5701 tggtcaagaa gcagaccaaa ctttcttttc accaggccgt attaatttga ttggtgaaca
     5761 cacagactac aacggtgggc acgtttttcc agctgctatt tccttaggaa cttatggtgc
     5821 agctcgcaag cgtgatgacc aagtcttgcg tttctactca gctaactttg aggacaaggg
     5881 cataattgaa gtgcctctcg ctgacctcaa gtttgaaaaa gagcacaact ggaccaacta
     5941 tccaaaaggg gttcttcatt tcttgcaaga agctgggcac gtgattgaca aaggttttga
     6001 tttttatgtt tatgggaata tcccaaatgg ttctggcttg tcttcttcag catccttgga
     6061 gatcttgaca ggagtcgtgg cagagcatct ctttgattta aaactagagc gtctcgattt
     6121 ggttaaaatc ggaaaacaaa cagaaaataa ctttatcgga gtcaactctg gtatcatgga
     6181 ccagtttgct attggtatgg gggctgatca acgtgctatt taccttgata ccaacacctt
     6241 agagtatgat ttggtgccac ttgatttgaa ggacaatgtc gttgttatca tgaacaccaa
     6301 caaacgccgt gaattggcgg actctaaata caatgaacgt cgtgctgagt gtgaaaaagc
     6361 agtggaagaa ttgcaagttg ccttggatat tcagaccctg ggtgaattgg acgagtgggc
     6421 cgttgaccaa tatagctatc tgattaaaga tgaaaatcgt ttgaaacgtg ctcgccatgc
     6481 tgtgcttgaa aaccaacgta cccttaaagc tcaagcagcc cttcaagcag gtgatttgga
     6541 aacatttggt cgtttgatga atgcgtcaca cgtttctctg gagcatgatt atgaagtaac
     6601 tggtttggaa ttagataccc ttgttcacac agcttgggca caagaaggag ttctcggtgc
     6661 tcgtatgaca ggggctggtt ttggtggctg tgccattgcc ttggttcaaa aagatactgt
     6721 tgaggccttt aaggaagctg taggcaaaca ctacgaggaa gtagttggat acgctccaag
     6781 cttctatatc gctgaagttg caggtggcac tcgcgtcctt gactagtcaa aaggaggctc
     6841 tatagtgacc ttagtagata aatttgtaac acatgtcatt tctgaaagtt catttgagga
     6901 aatggatcga atctacctga ccaaccgtgt tttgtcacga gtgggagaag gtgttttgga
     6961 agttgagacc aatctggata aattgattga cctcaaggac cagctagttg aggaaaccgt
     7021 tcgattagag acgattgagg atagtcagac tgcgcgtgaa atccttggta ctgaattgat
     7081 ggacttggtg actccttgtc cgagtcaggt caatcgtgac ttctgggaag cctatgccta
     7141 ctctcctgag caagcgatag aggattttta tcaactcagt cagaaaaatg actacatcaa
     7201 actcaaggcc attgctagaa atatcgctta tcgtgttcca tctgactacg gagaacttga
     7261 aattaccatc aatctctcta agcctgaaaa agatcccaaa gagattgtgg cagccaagtt
     7321 ggtgcaagct agtaattatc ctcagtgtca gctttgtcta gagaatgagg gctaccatgg
     7381 tcgagttaac cacccagctc gtagcaatca ccgtattatc cgttttgaaa tggttggtca
     7441 ggaatggggt ttccagtatt cgccctatgc ttactttaat gagcattgta tctttttaga
     7501 tggccagcat cgtcccatgg ccattagtcg tcagagtttt gaacgtctgt tggctatcgt
     7561 agaccagttt ccaggatatt ttgctggatc taatgccgac ctgccgattg tggggggctc
     7621 tattctaact catgatcatt atcagggagg ccgtcacgta tttcctatgg aattggctcc
     7681 cttgcaaaag gccttccgat ttgctggttt tgagcaggtc aaggctggaa ttgtcaagtg
     7741 gcccatgtct gtcctacgtt tgacttcgga ttccaaagag gatttgatca atttggctga
     7801 taagattttg caggaatggc gtcagtattc agattctagt gtgcagattt tagcagagac
     7861 agacgggaca ccgcatcaca ccatcacacc aatagcgcgt aagcgtgatg gacagtttga
     7921 gttggacttg gtcttgcgag acaatcagac ttcagcagag catcctgatg gcatctatca
     7981 tccccacaag gatgtccaac atatcaagaa ggaaaatatc ggcttgattg aggtcatggg
     8041 cttggcaatc ttgccaccac gtctgaaaga agaagtagag caagtcgcta gctatcttgt
     8101 aggagaagct gttacagttg ccgattatca tcaggagtgg gcagaccaac tcaaatccca
     8161 acatccagac ctaacggata aagaaaaagc ccttgcaatc gtcaaggact ctgtgggtgc
     8221 tatctttgtg cgtgtacttg aggatgcagg agtctacaag cagacagaac aagggcagac
     8281 agcctttatg cgctttgtgg aacaggtcgg aattttacta gactaggagc tttctccttg
     8341 cacagtccta taaaaagtag tatcatagtg tcgtttgaaa tatcaggagg aaacgatgaa
     8401 agactttcat tttgacgcta tatctgcctt tgaaaattac gaaattgaaa aaatgagaga
     8461 tggtcacgtt gtggtgacga ccaaagtagt gaactcatcg ctcaactact atggcaatgc
     8521 ccatggtggc tatctattca cgctatgtga ccaaatcagt ggtttggtgg ttatctcgct
     8581 gggacttgat ggggtgacac tccaatcctc tatcaactac cttaaggcag gaaaactcga
     8641 cgatgtattg accattaaag gagaatgtgt ccatcaaggt cgtacaacct gtgtgatgga
     8701 tgtggatatc accaatcaag agggcagaaa tgtctgtaag gcaaccttta ccatgtttgt
     8761 cacaggccaa aggtctgagg aaagacgggt aagtatataa agaaaggtga gtgggataaa
     8821 tttatctcac tcatttttaa tttatgagat atgttagaag gaaatataaa agagagtgat
     8881 gaaatacaaa tgtaataggt acatatatgt ggtatactag ttatagtaga ttttaattgc
     8941 ttatatcgag tgagttctca tattagtgag gaatttttaa atggaattac actttaattt
     9001 agaattagta gaaacctata aaagtaatag ccaaaaggca cgtatcttaa cggaggattg
     9061 ggtttatcgt cagtcttatt gccctaattg tgggaacaat cccttaaatc attttgaaaa
     9121 taatcggcct gtagcagatt tttactgtaa tcattgtagt gaggagtttg aactaaagag
     9181 caaaaaagga aatttttcat caacaatcaa tgatggtgct tatgcaacga tgatgaagcg
     9241 tgtgcaggca gataataatc ctaatttctt ttttttaact tacacaaaaa attttgaggt
     9301 aaataacttt cttgtccttc cgaagcaatt tgttacaccg aaatcgatta ttcaaagaaa
     9361 accacttgca ccaactgcta gacgagcagg ttggattggt tgtaacattg atttatcaca
     9421 agtaccttct aaaggaagga tatttcttgt gcaagatgga caagttagag atccagaaaa
     9481 agttacaaaa gaatttaagc aaggtttatt tttaaggaag agctctctgt catcaagagg
     9541 ttggacaata gaaattctaa attgtataga taagatagag ggttcagaat ttacccttga
     9601 agatatgtat cgttttgaaa gtgacctaaa aaatatcttt gttaagaaca atcatatcaa
     9661 agaaaagatt aggcaacagc ttcaaatatt aagagacaaa gaaataatag aatttaaagg
     9721 tagaggaaag tatcggaaat tatgaaaacg aaacaacttg ttgcatcaga agaggtgtat
     9781 gatttcttaa aagtcatctg gcctgattat gaaactgaaa gccgttacga taacctaagt
     9841 ttaatcgtct gtaccttatc agatcccgat tgtgtgagat ggttatctga aaatatgaaa
     9901 tttggtgacg aaaaacaact agctttgatg aaggaaaaat atgggtggga agtaggagat
     9961 aaattgccag agtggctaca tagctcctat catagattat tgttaatagg tgaattattg
    10021 gaaagcaatc taaaactgaa aaagtataca gtagaaatta cagaaacttt atcacgttta
    10081 gtaagtatag aggctgaaaa tccagatgaa gccgaacgac ttgtaagaga aaagtataag
    10141 agttgtgaaa ttgttcttga tgcagatgat tttcaggact atgacactag catatatgaa
    10201 taggtagatg tttttatttt gtcacacaaa aaagaggctc gcacctcttt ttcttatttc
    10261 tttttatgat ttaatacggc attgaggaca atagcgagta ggctggctac gacgattccg
    10321 tttgagaaga acatttggaa ggctgtcggc atgctgacaa agagattact gttgttgaga
    10381 ccgacacctg cagcgattga aacagctgcg ataaggaagt tgtgttcatt gttagcaaag
    10441 tcaactcggg cgaggatttg catcccttga atagatacaa aaccaaacat caccagcatg
    10501 gcaccgccga ggacggagct tggaatgatt tgggcaaggg caccaaactt aggaagcagt
    10561 ccaaggagaa ccaggaaacc agctgcgtag tagattggca ggcgtttttt gatgcctgac
    10621 aatttaacca aaccaacgtt ttgtgaaaat ccggtgtaag ggaaggtgtt aaagattcct
    10681 ccgagaagta ccgccaaacc ttctgcgcgg taaccgttgc gaaggcgcgt gctgtcgatt
    10741 ggatcttttg tgatatcaga caaggctaga taaacaccag ttgactcaac catagacacc
    10801 gttgcgatga tacacatcat gacaatagat gagatttcaa aggttggcat cccaaagtag
    10861 agtggagttg ggacatggac aagtggagct accgcaacag gagagaagtc caccaagccc
    10921 atagtagcag caatggcagt tccaacaacc agaccaatca aaatagagat agacttgata
    10981 aatcctttgg taaagatgtt gatcaagagg ataatcagaa cagtaatagc tgcaagcaag
    11041 agactttgac cagttggctc tggaacgtta tttcccatat ttccaatagc gacagggatc
    11101 aaggttaaac caatcgtggt aataacagat cctgttacga tagatgggaa gagattggct
    11161 acttttgaga agatgcctga aacaagaacc acgtaaatcc cagatgcgat aagggcacca
    11221 aacatagcgc cactaccatg gctttgccca atcataatca agggagcgac cgactggaat
    11281 gcaactccaa gaacgactgg gagtccaatc ccaaagtatt tgttgagttg gagttggagg
    11341 aaggttgcca ccccacacat gaagatatct gtagaaatca ggtaggtcaa ctgctcagct
    11401 gaatagccaa gggctgtcgc aatcatgatg ggaaccagga tagatcctga gtacatggct
    11461 agtaagtgct gcaagcccag aacggctgct tgcgagtgtt tttcttgagt ttgcattaga
    11521 gatctgcctc cttaaatacg acctgaccat tttcaaaacg atccaagcga gcaagtgata
    11581 ggacagggta gcctgctttt tcaagcaaat cacgaccatc ttggaaggat ttctcaatca
    11641 cgataccgat agcttggact gtggcaccgg cctgttcgat gatttgaatc aagcctttag
    11701 cagcttggcc attagcaagg aaatcgtcga taatcaaaac cttgtcctct ggtgagagga
    11761 attttccagc gatagaaaca gtgctggtca cctgcttggt aaaggagtag acttgagcag
    11821 ttaagatgcc ttcgttcatg gtgatgttct tagctttttt ggcgaaaatc atgggaacgt
    11881 ttaaggcttc agctgtaaaa acggctgggg caatacccga cgcttcaatg gttacgacct
    11941 tggtaatgcc agtagcagca aatttttccg caaaaacctt accaatctct cgcatcaagc
    12001 taaagtcaac ttggtgggtt aaaaaggaat ctaccttgag gatgttatca cccaagatat
    12061 gcccatcctt gaggatgcgc tcttctaata atttcataag acctcctaaa gtctaaaagt
    12121 taatttactt gttgtttaaa tatttctata gtgatccctt ttgctaatac tatatatttg
    12181 ataaaactat tacgagcgaa gcgagtctta tcaaatattt cccgttgtag tggtatcata
    12241 gacaataatc ttgttattgt ctatgacggg atttttgaga gtaaaatagt tcggggaact
    12301 attttagcct aagcctagaa atgaaagagc taggggctca aaaattaggg atgaaattcc
    12361 ctggattcct gaaattattc acaggataat ttcacctccc gtccgcacta attaagggaa
    12421 atattaaaaa tattcaaaaa agacctactt aatctctaag taagtcccct aaatagacat
    12481 ggcaaaaacg gccatatctc actgctgact tacttattgt taggtgttcc ggcaccttgt
    12541 agaaacgtcg tgccaattca cgacataaac aagtaaaacg atattcaatt ttaaataggc
    12601 ttgagccaat gtttttattt tacactaaat aactttagaa atcaactatt ttgttagtat
    12661 tttggtttaa aaagcgaaca aaaagaagag agggtgaaca aaaactccat tgtaagctaa
    12721 catttatact aaatgaaaat caaagagcaa actaggaagc tatccacaac ctcaaaacac
    12781 tgttttgagg ttgtggatag aattgacaga gtcagtatca tatacctacg gtaaggcgac
    12841 gttgacgtgg cttgaagaga ttttcgaaga gtattagaag atttttccat cataaaaggc
    12901 atactatcaa gtttttaaac acctgacaat atgccttttt ctaactttaa agacttttcc
    12961 caatttttat tattctactc gctaaatctt aaaaaatagc catctggatc caaaactgca
    13021 aatttatgag gatagatata gggatcactg acacgaaact ttcttttggt caagggacga
    13081 taaataggat agtttgcctc catcactttt tgatagagtt ttggaacatc ctttatgcca
    13141 aaggagagat tgactccacg accaaagggg taggtcagtt cagctagttg atcctttgtt
    13201 ccctcctcta acattagttg acactcttca agagaaagag aaagttttct tctggacgtt
    13261 ggtattcaat cctaaaaccc agtaaaccac agtagaagga ccgggactgt tcgatattcg
    13321 atacaagaaa ctcgggaatg accgcattgt agtccatata gaaaatcctt acaagtcaat
    13381 ttccaagaca atcggtgtat ggtcttggcg agcacctgag tcaatcatat cagatttagt
    13441 gaccttgtca gcgatacggt tacttgtgag ccagtagtcg attctccagc ctgtattgtt
    13501 gattttagaa gttttgctgc gttgtgccca ccaagtgtag cgttcaggaa catcgccatg
    13561 aacatggcgg aaggtatcag taaatccagt tgccaatagg ttggtaaatc cagcacgttc
    13621 ctcgtcagta aatccaggtg aacggcggtt gctagcagga tttgcaaggt cgatttcatt
    13681 gtgggctacg ttgtagtcac cggtcgcaag gactggtttt tctttgtcta gttcagccaa
    13741 atactccgca tatttgacat cccagacttg gcgttcttcc aagcgtttaa gaccatcgcc
    13801 agcatttggt gtgtaaactt gggtcacgaa aaatgcatca aattctagag tgatgatgcg
    13861 gccttccaag tccatggtag aaggggcacc gatttctggg aaagtgacag tgggtgtaag
    13921 ttctttctta taaaggaaca tggttccagc atagccttta cgggcaggct cttgggaaga
    13981 gcgccacgtg ttttcgtagc ctgggaagag ttcttctaaa atttccacgt gtttctttgt
    14041 aggtcctttg gcagaaagct tggtttcttg gatagcaatg atatcagcat tttcagcgac
    14101 caaggtttgt aggacttctt gggacaattt ggcacgagct gagtcactag ttagggcagc
    14161 gtttagggaa tcaatattcc atgagataag tttcataaag ttaccttttt cattcagatt
    14221 atagatttta ttataccaaa aaaagatcta tttccccaac gtatggtttg aaaaattact
    14281 ctctttcgtt tataattaag aatgatttta tgaaagggag tgaaaataca tgaaattcta
    14341 ctcttatgac tatgtactca gccaaatcgg tcagcaaaat ggtatcatgg ttggctttgg
    14401 gattgttcta ttagctgtga cagttttttt gcttttaagg cataccatga taaaaaggga
    14461 accgaatttc gtgagttggt catgatttca gctctggcct tatttagctc tgcttttggt
    14521 cagcatcacg acttatcaaa acaatcaagt ttctaacaat aaatttcaaa cttcacttca
    14581 tttcatcgag gttgtttcca aagatttggg agtagacaag tcagaagtct atgttaatac
    14641 ttccacaaac acagatggcg cacttatcaa ggtgggagat cgctattatc gtgccctaaa
    14701 cggaagtgag ccagacaagt acctgttaga gaaagtcgaa ttgtataaga cagacgcaat
    14761 tgaactggtg gatgtgaaca aatgacactt aattatatcg aaattttaat caaactggtc
    14821 ttgactctca aatagttcaa caacaatgtt cactttatga aacgtttgat tgatggtaag
    14881 ccaactctcc ttatcaaaaa tgggaatatt gacccataag cctgtcgttc agttggtttg
    14941 tctgcatcgg atgtagccct caaacttcgt agccaaggga ttttccagat gaagcaagtc
    15001 aaacgagctg tgcaagagca aaatgggcaa ctcatcgttg tgcaaatggg agatgaaaat
    15061 cctaagtatc cagttgtgac tgacggtgtg attcaagtag atgtcttgga atcgattggt
    15121 cgtagcgaag agtggttgct tgataacctc agcaaacaag ggcatgacaa tgtagccaat
    15181 atctttattg ctgaatatga caagggtgct gttacagtcg taacttatga ataagaaaaa
    15241 cctggggtct tgtactcttc gaaaatctct tcaaaccgcg tcaacgtcgc cttgccgtat
    15301 gtaggttact gacttcgtca gttctatcta caacctcaaa gcagtgcttt gagcagcctg
    15361 cggctagttt cctagtttgc tctttgattt tcattgagta ttggcctcag gcttccattt
    15421 gcaatcagaa agggatttta tgtccattat tcaaaaactt tggtggtttt tcaagttaga
    15481 aaaacgccgt tatctagtcg ggattgtggc cctggtcttg gtttccgtcc tcaatctcat
    15541 tcctcctatg gttatggggc gggtcattga tgccatcaca tcggggcaat taacccagca
    15601 ggacctcctt cttagcctat tttacttgct acttgcagcc tttggtatgt actatttgcg
    15661 ctatgtgtgg cgtatgtata tccttgggac ctcttattgc ttgggacaga tcatgcggtc
    15721 tcgcttgttt aagcatttca caaaaatgtc gtcagccttt tatcaaacct atcggacggg
    15781 tgatctgatg gcacacgcaa ccaatgatat caatgccttg actcgtttag caggtggcgg
    15841 tgtcatgtct gcggtggatg cctctatcac ggctctggtg actttgttga ccatgctctt
    15901 tagcatctca tggcagatga ctcttgttgc cattctcccc ctacctttca tggcctatgc
    15961 gactagtcgc ctagggagaa agactcataa ggcctttggc gaatcccaaa ctgctttttc
    16021 tgaactcaat aacaaggtac aggagtccgt atcaggtatc aaagtgacca agtctttcgg
    16081 ttatcaggca gacgagttga agtcttttca ggcagtcaat gaattaacct tccaaaagaa
    16141 cctgcaaacc atgaaatatg atagtctctt tgaccctatg gttctcttgt ttgttggttc
    16201 gtcctatgtt ttaacgcttt tggttggctc cttgatggtt caggaagggc agattacagt
    16261 tgggaatcta gtcaccttta tcagctattt ggatatgctg gtctggcctc ttatggccat
    16321 cggcttcctc tttaatacta ctcagcgagg gaaggtttct taccagcgga ttgaaaatct
    16381 tttgtctcag gaatctcctg tacaagaccc ggagtttcct ctggatggta ttgaaaatgg
    16441 gcgtttggag tatgccattg acagctttgc ttttgaaaat gaggaaacac tgacggatat
    16501 tcactttagt ttggcaaaag ggcaaacact gggcttggtt gggcagacag gctctgggaa
    16561 aacgtcctta atcaagctcc tcttgcgtga atacgatgtg gataagggcg ccatttatct
    16621 aaacggtcac gatattcggg actatcgtct gacagacctt cgcagtctca tgggctatgt
    16681 tcctcaggac cagtttcttt ttgcgacttc aatcctagac aatatccgct ttggcaatcc
    16741 taacttgccc ctttcagcgg tcgaggaagc tactaagcta gcccgagttt accaagatat
    16801 tgtagacatg cctcaaggat ttgatacgct gattggtgaa aaaggagtca gtctttctgg
    16861 tggtcaaaag caacggttgg ctatgagtcg ggctatgatt ttagaccctg atatcttgat
    16921 tttggatgat tccttatccg ccgtagatgc caagacagag tatgcgatta tcgacaacct
    16981 caaggagacg cgaaaggaca agacaaccat tatcactgcc catcgcctga gtgcagttgt
    17041 ccatgcagat ttgattttag tcctgcaaaa tggtcaaatt atcgaacgag gcaggcacga
    17101 agacttgcta gctttggatg gctggtatgc ccaaacctac cagtctcagc agctggaaat
    17161 gaagggagaa gaagatgcag aataaacaag aacaatggac tgtattgaag cgcttgatgt
    17221 cctatctcaa gccttatgga ctccttacct ttttggcact cagttttctc ctagcgacga
    17281 cggtcattaa aagtgtcatt ccccttgtgg cttcccactt tatcgaccag tatctcagca
    17341 atcttaacca actagccgtg accgttttgc tggtctacta tggtctctac atcctacaaa
    17401 ctgtagttca gtatgtcggc aatcttctct ttgcgcgcgt gtcttacagt attgttaggg
    17461 atattcgtcg ggatgccttt gccaatatgg agaaactggg catgtcttac tttgacaaga
    17521 cgccagcagg ttctatcgtt tctcgtttga ccaacgatac cgagacgatt agtgatatgt
    17581 tttctgggat tttatccagc tttatctcag cagtttttat ctttctgaca accctttata
    17641 ccatgttggt gctggatttt cgtttgacag cattagtctt gctctttctc cccttgattt
    17701 tccttttggt caatctctat cgaaaaaagt cagtgaaaat catcgagaaa accagaagtc
    17761 tcttgtcaga tatcaatagt aagctggcag agaatatcga gggaatcagg attattcagg
    17821 cttttaatca agagaagcgc ctgcaggcag aatttgatga aatcaaccaa gagcacttgg
    17881 cctatgccaa ccgttctgta gccttggatg ccctcttttt gagacctgcc atgagtttgt
    17941 tgaaacttct aggttatgct gtcttgatga cctattttgg ctatcgtggt ctttctatcg
    18001 ggataacggc cgggaccatg tatgctttta tccagtacat caaccgcctc tttgaccctt
    18061 tgattgaggt gacgcaaaac ttttcaacac tgcaaacgtc tatggtttct gcaggccgtg
    18121 tctttgcctt aatcgatgag aggacctatg agccccttca agaaaatggg caagccaaag
    18181 tcaaagaagg caatatccgt tttgaacatg tgtgtttctc gtatgacggt aaacatccga
    18241 ttctggatga catttctttc tctgttaata agggtgaaac cattgccttt gtaggtcata
    18301 caggttcagg gaaatcgtct attatcaatg tcctcatgcg cttttatgaa ttccagtcag
    18361 ggagagttct cttggatgat gtggatatca gggatttcag tcaagaagag ctgagaaaaa
    18421 acatcggttt ggttttacag gaacccttcc tctatcatgg aactattaag tccaatatcg
    18481 ccatgtacca agaaatcagt gatgagcagg ttcaggctgc ggcagccttt gtggatgcag
    18541 attcctttat tcaagaactt cctcaggggt acgactcccc tgtttccgag cgtggttcga
    18601 gcttctctac tgggcagcgc cagcttcttg cctttgctag aacagtcgcc agccagccta
    18661 aaatcctgat tttggatgaa gcgacagcca atattgactc tgaaacagaa agtttggttc
    18721 aagcttctct ggcgaagatg agacagggcc gaacaactat tgctatcgct caccgccttt
    18781 ctactattca agacgccaac tgcatctatg tcttggataa gggacgcatt atcgagagtg
    18841 gaacccatga ggaactcttg actctgggag gaacctatca caagatgtat agtttgcagg
    18901 caggggccat ggcctatact ctttgaaaat ctctttaaac catgtcagct ttatctgcaa
    18961 tctcaaagct gtactttgat tttcattgag tactagaagg aaatccttca aattacagat
    19021 ttctttcacc gccttttcca ttttgtggta taatgaaaaa tgttgacaaa tagtataata
    19081 aaaacaaagg agaacagcat gctgaaatgg gaagacttgc ctgtggaaat gaaatcaagc
    19141 gaggttgagt cttactacca gcttgtctct aaaaggaagg gttcgctgat tttcaagcgt
    19201 tgcttggact gggttttggc cttggtctta ctggttctaa cttctcccat ctttctcatc
    19261 ttgagcattt ggatcaagtt ggatagcaag gggccagtga tttacaagca agagcgtgtg
    19321 acccagtaca accgtcggtt caagatttgg aagttccgta ccatggtgac ggatgcggat
    19381 aaaaaaggaa gtctggtgac ttctgctaac gatagccgta ttaccaaggt tggaaatttc
    19441 atccgacgtg tccgtttgga cgaactgcct cagttggtca atgtccttaa aggtgagatg
    19501 tcctttgtcg gtacacgacc tgaagtgcca cgttatacag agcagtatag ccctgaaatg
    19561 atggcaacct tgctcttgca agcaggaatt acctctccag ccagcatcaa ctacaaggat
    19621 gaggacacca tcatcagtca aatgacggag aaaggtctgt cagttgatca ggcctatgtg
    19681 gagcatgttc ttcctgaaaa gatgcgctat aacctcgcct atctccgaga gtttagtttc
    19741 tttggggaca tcaaaatcat gtttcaaacc gtgtttgagg tactaaaata aagtagtcat
    19801 aagaaaatga gtacagataa aaggagcaaa tcaatgccaa attacaatat tccattttca
    19861 ccgcctgata tcacagaagc agaaattgct gaagtagcgg ataccctgcg ttctggttgg
    19921 atcacaacag gtcctaaaac aaaagaactg gagcgccgct tgtctcttta cacacagaca
    19981 cctaagactg tttgtctcaa ctctgcgaca gccgctctgg agttgatttt acgcgttttg
    20041 gaagtgggac ctggtgatga agtcatcgtt ccagccatga cctatacggc ttcatgtagt
    20101 gtcattacgc acgtgggagc aacccctgtc atggtggata tccaagcaga tacgtttgag
    20161 atggactatg acctgcttga gcaagctatc actgagaaaa ctaaggtgat tatcccagta
    20221 gagctcgcag ggattgtttg cgattatgac cgtttgttcc aagtcgtgga gaaaaaacgt
    20281 gacttcttta ccgcttcaag caagtggcaa aaggccttta accgtattgt cattgtctct
    20341 gatagtgccc acgctttggg atctacttat aaaggacaac cttctggttc tatcgctgat
    20401 tttacttcct tctcattcca tgctgttaag aactttacaa cggcagaagg tggaagtgcg
    20461 acttggaaag ccaatccagt gattgatgac gaagagatgt acaaggaatt ccaaatcctt
    20521 tcccttcacg ggcaaactaa ggatgctctt gccaagatgc aactggggtc atgggaatac
    20581 gatatcgtta caccagccta taagtgcaac atgaccgata tcatggcttc acttggtttg
    20641 gtacaattgg accgctatcc aagtttgttg caacgccgta aggacattgt ggaccgctat
    20701 gatagtggtt ttgcaggttc tcgcatccat cctttggcac acaagactga aactgtcgaa
    20761 tcttcacgcc acctctacat cacccgtgta gaaggagcaa gcctagaaga acgcaacctc
    20821 atcatccaag aattggctaa agcaggaatt gcaagtaatg ttcactacaa accgcttcct
    20881 ctcttgacag cctataagaa tcttggattt gatatgacga actatcctaa ggcctatgcc
    20941 ttctttgaga atgaaattac cctccctctt catactaaat taagcgatga agaagtagac
    21001 tatatcattg agactttcaa aacagtttct gaaaaagtgc taactttatc aaaaaaatga
    21061 caaactacag tcaagcgaaa gtgatcctgt ccctaaaaag tctaattgag tgtaaaaact
    21121 gttgttttca attgataata gtttacacct gtagttgagg cctctttctc ctcagagaga
    21181 gaatttttat aggattttcc tttcttgtgg gagtcccgtg gtttgaaata agatgtgagc
    21241 aatttggtat agcatttaga atccttacta gacatcattt agaaaatcta gtgtcttgtt
    21301 ctagttttca attcacccta ttttttgaaa gacgtgagtt tccatgagtg agattgtgga
    21361 aactagcgtc ttttttttgt tttcagaata ttgttcaaag ttttgtgcct gtctttcatg
    21421 ttctagtcat tcttttgcat gatagaattt atagcatgtt gatattataa taacgcaaat
    21481 atcccatatg tttagtgatg cttgctatac atcattagat ctcctgcgag acaatctata
    21541 aaacacttgt ctacgattac ctatatgccc tattccagta ttttagaagc actgcatcta
    21601 tttttatcga ggttaaatct agcttttata gaaggtctat ttaagaaata tattgtagtg
    21661 ttttagtttc aatccgccat atgagcgata ttcaggtaaa tatccctggc gaatgcttgt
    21721 atgacaaggt atttgttctt tcatttataa tttacaacat atcaacaaat ttaaatatag
    21781 taaatgggat attttatatt caagctaaga aagatagcat cacttttgaa tggaaggcta
    21841 aagagcaaac taggaagttg gccatagata gctcaaaacc ctgctttgag gttgtagata
    21901 tagtaaaatg aaacaagaat aggacaaatt gatcgggaca gttaaatcga tttctaacaa
    21961 tgttttagaa gtagaggtgt actattatag tttcagtcta ctatagaact gaccaagtca
    22021 gtaacctaga cttagggcaa ggcggcactg acctagtttg aagagatttc cgaagagtat
    22081 aaattttaat attttcttgt gttattcctt gacaattcaa tttggaaaat atatgataaa
    22141 aataatgaca gcggtgtcat tctatctatt ttaagaaaag taataatcaa ttgttaaaaa
    22201 tagtaaaaaa attggaggtt ctgatgaaat attttgttcc taatgaggta ttcagtattc
    22261 gtaaattaaa ggtggggact tgctcggtac tattggcaat ttcaattttg ggaagccaag
    22321 gtattttatc ggatgaagtt gttactagtt cttcaccgat ggctacaaaa gagtcttcta
    22381 atgcaattac taatgattta gataattcac caactgttaa tcagaatcgt tctgctgaaa
    22441 tgattgcctc taattcaacc actaatggtt tagataattc gttaagtgtt aatagtatca
    22501 gctctaatgg tactattcgt tccaattcac aattagacaa cagaacagtt gaatctacag
    22561 taacatctac taatgaaaat aagagttata aggaagatgt tataagtgac agaattatca
    22621 aaaaagaatt tgaagatact gctttaagtg taaaagatta tggtgcggta ggtgatggga
    22681 ttcatgatga tcgacaagca attcaagatg caatagatgc tgcagctcaa gggctaggtg
    22741 gaggaaatgt atattttcct gaaggaactt atttagtaaa agaaattgtt tttttaaaaa
    22801 gtcatacaca cttagaattg aatgagaaag ctacaattct aaatggtata aatattaaga
    22861 atcacccttc cattgttttt atgacaggtt tatttacgga tgatggtgcg caagtagaat
    22921 ggggcccaac agaagatatt agttattctg gtggtacgat tgatatgaac ggtgctttga
    22981 atgaagaagg aactaaagca aaaaatctac cacttataaa ttcttcaggt gcatttgcta
    23041 ttgggaattc aaataacgta actataaaaa atgtaacatt caaggatagt tatcaagggc
    23101 atgctattca aattgcaggt tcgaaaaatg tattagttga taattctcgt tttcttgggc
    23161 aagccttacc caaaacgatg aaggatgggc aaatcataag taaggagagc attcagattg
    23221 aaccattaac tagaaaaggt tttccttatg ccttgaatga tgatgggaaa aaatctgaaa
    23281 atgtgactat tcaaaattcc tattttggca aaagtgataa atctggggaa ttagtaacag
    23341 caattggcac acactatcaa acattgtcga cacagaaccc ctctaatatt aaaattttaa
    23401 ataatcattt tgataacatg atgtatgcag gtgtacgttt tacaggattc actgatgtat
    23461 taatcaaagg aaatcgcttt gataagaaag ttaaaggaga gagtgtacat tatcgagaaa
    23521 gcggagcagc tttagtaaat gcttatagct ataaaaacac taaagaccta ttagatttaa
    23581 ataaacaggt ggttatcgcc gaaaatatat ttaatattgc cgatcctaaa acaaaagcga
    23641 tacgagttgc aaaagatagt gcagaatatt taggaaaagt atcagatatt actgtaacaa
    23701 aaaatgtaat taataataat tctaaggaaa cagaacaacc aaatattgaa ttattacgag
    23761 ttagtgataa tttagtagtg tcagagaata gtatattcgg tggtaaagaa ggaattgtta
    23821 ttgaggattc aaagggtaaa ataaccgttt taaataacca attttataat ttatccggta
    23881 agtatatatc attcatcaaa tctaatgcaa acgggaaaga acctgttata cgtgatagcg
    23941 atggtaattt caatattgta acggagaatg ggctttacaa aattgtaaca aataatttaa
    24001 gtgataaaaa cgaaaaagaa aaaaacaaag aggaaaaaca atctaattca aataatgtaa
    24061 ttgatagtaa ccagaagaac ggagagttta actcaagtaa agataataga caaatgaatg
    24121 acaagatcga caataaacaa gataataaga cagaagaagt aaactataaa atagttggag
    24181 atggcagaga aactgaaaat catattaata aatctaaaga aatagtagat gtaaaacaaa
    24241 aattaccaaa gactggttcg aacaagatta tggaactatt cttaacagtg acaggaattg
    24301 gtttactttt gacactaaaa gggttgaagt attatggtaa agataaataa aatttgttcg
    24361 atacaaggaa gttccgtaga aaatgaggat attgtaggtt cacaaaatca gtatttttgg
    24421 attattggtg gagctacaga tttatataat tctaaagagg agataggtta ttcagtctca
    24481 gaagttgtac atattttatc agaaagtttg tcggttaatt gtaaagaatc aaaaactctt
    24541 aaacaaatat ttgaaactgc tttactcgag gttaaagatg aaatcggttt aaactcatat
    24601 gaattaacag agtataataa aatgaaataa taataggaca aatcaatcag gacagtcaaa
    24661 tcgatttcta acaatgtttt agaagtagag gtgtactatt ctagtttcaa tatactatat
    24721 tatcgcttac caacatttgc ttttatattt gctaaacttt cagaaaaaaa gttggagtat
    24781 atgatgctag gtgactgcgt catgttagta aacgaaatgg aaataacgga tcatagagta
    24841 gataacttat ttgaaaaagg gaaaaatgag ataaaagatc caattggtac aaatagtgtt
    24901 ttaaataaaa aaattatttt acaaaaaatc agaaaattat ctaatcaacc gagtgggtac
    24961 tggataggtt cgttggatga gagattttta gaccatgcta ttattaatca aatagatgtt
    25021 actagtgaac aaattgtttt aatgagcgat ggcttttatg aattctatca aaataatcaa
    25081 aataaaactt ttgaagagtt aattaagatg agatttaatt cttctgctat tgatccaatc
    25141 tatggaaaga aagatgatgc aagtattgta gttattgatg tttgatatat tgtttaaaat
    25201 attaattgtt actattgaac tttgttaaga agaggtacct aaatgttaag gttatattta
    25261 gaaaatgaaa ttatagaatt atcaaataat ttagagacca tttgggtatc tgtgcttgat
    25321 aaatatgaga agttatttga atatttatca aatgaagaac gaatagaatt gattaaagaa
    25381 gatttaatca taaatgagtc agttctaaat gttgataaaa aaggatatga gttaatttgt
    25441 ttacaacatc ccgtttcata tgacttaaga agaattatta gtgtaataaa aatatcaact
    25501 gacattgaac gtattgggga tagaattgtt gaaattttaa aaaatctaca gattcttcaa
    25561 aataatgaaa ttttgaagaa aattatttca gaaataaaaa tacttcatga agttatcgga
    25621 ctgcatatga atagggctat atcttgttat agagaggaac aatctggatg tttagatatg
    25681 gttgttatac aaaaacagaa tgagatagaa gagcttagta caaatattga aaagaaaata
    25741 atgaattaca tatttgaaga tgatgggaat gtttctgaag taattggtgc tttagatatt
    25801 attcatcacc ttgataaaat tgctcatact acgcaatcaa tttataaatg gataatgtat
    25861 agaaaatatg ggaacataaa ttagaaagaa aaatatatga aaacaattat tgataatttt
    25921 gttgatagag taattgaata cggaatgtat aatgaaattg acaaaatata tgtgaaaaat
    25981 agagtactag cgttaatagg tgaggaggga actgatcgca tttccgatga aaatgacctg
    26041 aaacaaataa aagattactt agtggaaatc gccttaaaaa acggtaaaat taaagattta
    26101 atcgaggaaa aggaatgttt aggagcagag ttaatgaatt tcatagttcc tttacctagt
    26161 cgattaaatg atattttttg gagttcatat gatatatcac ctcaagaagc agttgaagag
    26221 ttttataagt taagtaaaga tagtgattat attaaaactt ctgctattgc taagaatatt
    26281 gagtttcgag catcaactaa atacggagag ctagagatta cgataaattt gtcaaaaccc
    26341 gaaaaagatc caaaaacaat tgctgctgaa aaattagtaa aagccactaa ttatcccaaa
    26401 tgtttactat gtatggaaaa tgaaggatat caggggcgaa taaattatcc agcacgttcg
    26461 aatcatagaa ttattcgatt gaaacttggt gacgaagtat ggggattcca atattctccc
    26521 tacttatact ttaatgagca tgcgatattt ttaaatagtc aacatgtacc aatggctatt
    26581 acctctaaaa catttgaaca attattggag attgttgata ttttgccagg atattttgct
    26641 ggttcaaatt ctgatcttcc tatctcagga ggctccattc ttagtcataa ccactaccag
    26701 ggagggaaac atattttccc aatggaaaaa gcaaaatttg agagtgaatt tcgttttaaa
    26761 gactttgagg atgttaatgc tggtattgta aaatggccaa tgtcagtaat taggttacaa
    26821 agtgaaaata aaaatcgctt gttagattta gctactaaaa ttctaaataa gtggagagaa
    26881 tattcagatt tagaagtaga catcattgct atgactgaag atgtcccaca ccatacggtg
    26941 actcctattg ctcgtaaagt ggacgggaga tatgaattag atattgttct aagagataat
    27001 catactactg aacagtaccc agatggtgtt ttccatcctc atcaagatgt acaacatatt
    27061 aaaaaggaaa atatcgggtt aatcgaagtg atgggacttg cgatattacc acctcgtttg
    27121 aaaccagagt tagaagaagt tggaaaatat cttttaggag aggataacgc aattgcggat
    27181 tatcatttag aatgggccga ccaattgaaa gaaaaatatc ctcgcattaa taaagaagag
    27241 gttaatagcg tagttcaaca cgaagcagga caagtgtttg cgagagttct ggaagatgca
    27301 ggagtttata agaatacacc gtctgggcat gaagcgttta tgagatttgt taagtcggtt
    27361 ggaattaatt aggaggaaac aaaaatggca atattggtaa caggcggagc tggttatatt
    27421 ggtagccata ccgtagtaga attactaaat ttaggaaagg aagtcatcat tgtcgacaac
    27481 ctttcgaact ctagcatctt ggtgctagac cgtattgaag caattacagg aatacgtccc
    27541 gtgttttacg aattagatgt ttgtgataaa ccagcattga gaaaggtatt tgaacaagaa
    27601 tcgattgatg ctgcaattca ttttgcaggt tataaagctg tcggagaatc cgtgcaaaag
    27661 cctgtgatgt actacaaaat aatattatga gtacattggc acttgttgaa gtgatgtcag
    27721 aatttaatgt taaaaagatt gtcttttctt caagtgcgac tgtatatgga attaacaatc
    27781 agtcacctct aattgagact atgcaaacaa gtgcgacaaa tccttatggg tatacgaaag
    27841 tgatgcttga gcaaatttta aaagatgttc atgtggcaga ttcagaatgg agtattgcgt
    27901 tgcttcgtta tttcaatcca attggtgctc atgagtctgg tttgattggg gaagatccct
    27961 caggaattcc taacaacttg atgccctata ttgcacaagt agcggtaggt aagctgtcag
    28021 aactaagtgt gttcggaaat gattatgata cgcttgacgg tactggtgtg cgcgattata
    28081 tccatgtagt agatttagca ataggacata taaaagcttt agaaaaagta tctgaaaaaa
    28141 cagatgttta tatctataac ctaggctcgg gagaaggcac tagtgtatta caacttgtaa
    28201 atacatttga aagtgttaat aagatcccta ttccttataa aatagttcca agacgttcag
    28261 gagacgttgc aacttgttat gcaaatgcag acaaagcata taaggaatta aattggagga
    28321 caacaaaatc gattgaagac atgtgtagag atacatggaa ttagcaatca aaaaatccca
    28381 atggctataa ttgatgatac tgtctatatg agtgctgtat tttggaaaaa ttacttaacc
    28441 ttttaatgaa atgcatattt aatgaaagat aaattaaaaa aaatgtttga cagcgcttga
    28501 caaaggaaac ggtttcattg tataatgtaa acatagtgac accgatgtca aatataaaaa
    28561 agaaggtctt tatatgaaaa acttaacaaa aattaagttc aaagagaatg gggaatttaa
    28621 tcatttccct gggaatacaa ttgtagcaaa tctttatact aaacaagatt tgatggaagt
    28681 tgttgatatt attcaatcac gttatagaga attaccattt atcgataagt ttactttaac
    28741 tccaaggaat tctattcaca tgactgtaat tgaattgttg tgccatgaaa atcgtgaaac
    28801 ggagttttgg agcagtaatc ttcctctaga tacaccttta caggaaatac atgattactt
    28861 tgctaaacaa cttgaaattt ttccattgtt ggatgaagaa attcatatgc gtataactga
    28921 aatgggaaaa caaaacatac tagttgaacc tgcagatgaa gcttctgcaa agagattaga
    28981 agaaattcgt acttatgtct cagaaaaagc aggtgtttgt ttccctaatc atgatagata
    29041 tcaattccat atttcaattg ggtatcttcg gattcctcta accgaagagg aggaagaaga
    29101 gtttactaaa gtcagagcag aattaactga aattttatta gagaagattc caactattac
    29161 tgtaaaccgt attgactata ctgtatttga agatatgaga caatttgttc catatcacga
    29221 aaaatttaaa taaaataata aaaaaggaga acttatcatg aaaaaaatga aagtttggtc
    29281 tactgtactt gcaacgggag ttgctcttac tacacttgct gcttgctctg gaggttcaaa
    29341 ttctacgact gcttcttcat ctgaagaaaa agctgataaa agtcaagaat tagtaatcta
    29401 ttcgaactca gtctcaaatg gtcgtggtga ttggttaact gctaaagcaa aagaagctgg
    29461 ttttaatata aaaatggttg atattgctgg cgctcaatta gcagaccgtg ttattgctga
    29521 gaagaataat gcagttgcag atatggtatt tggaattggt gctgttgact caaataaaat
    29581 tagagatcaa aaattactag tacagtacaa gcctaaatgg ttagataaaa ttgatcaatc
    29641 tttatcagat aaagataatt attataatcc tgtgattgtt caaccattag ttttaattgg
    29701 ggcgcctgat gtaaaagaaa tgcctaaaga ttggactgaa ttaggtagta agtataaagg
    29761 taaatattca atttatggtc ttcaaggtgg tacaggacgg gcaattctag caagtatctt
    29821 agttcgttac cttgatgaaa aaggagattt aggcgtatca gaaaaaggat gggaagttgc
    29881 aaaagaatac tttgcaaatg cctatactct tcaaaaaggt gaaagctcag ttgttaaagc
    29941 gttagataaa gaaagcccaa ttcaatacgg tatgatctgg ggttctggag cgttaatcgg
    30001 acaaaaagaa caaaatgttg aattcaaagt tatgactcct gagattggtg taccatttgt
    30061 aactgaacaa actatggttt taagcactag taaaaaacaa gcgttagcta aagaatttat
    30121 tgattggttt ggtcaatcag aaattcaagt agaatatagt aaaaaatttg gatctattcc
    30181 tgcaaataaa gatgccctaa aagagttacc tgaagatacg aaaaaatttg ttgatcaagt
    30241 gaaaccacaa aatattgact gggaagctgt tggaaagcat ttggatgaat gggtagaaaa
    30301 agctgaatta gaatacgtaa aataagaaat aagagttatt ttttatgtcc aagtctctct
    30361 attatttcta aatttaagga agaaataaag agaggctttt ggtttagtaa tagagggagt
    30421 tagtgagatg attaaatttg ataatattca aattaaatat ggtgattttg ttgcaattga
    30481 taatctgaat ttagatatac atgaagggga attctttaca tttcttgggc cttcaggatg
    30541 tggtaaatca actactttga gagcattggt aggtttttta gatccatcat caggaagtat
    30601 tgaagttaat ggaacagatg tcactcattt ggaacctgaa aagcgtggaa ttggtattgt
    30661 atttcaatct tatgcgctat ttccaactat gactgttttt gataatattg catttggttt
    30721 aaaagttaag aaggtagctc cagatgttat taaagctaaa gtatcagcag tggcagcaaa
    30781 aattaagatc tctgatcaac agttacagcg taatgtatca gaattatctg ggggtcaaca
    30841 acaaagggta gcattggctc gtgctctggt tcttgaacct aaaattcttt gtctagatga
    30901 accattgtca aaccttgacg caaaattacg tgtagatttg agaaaagagt tgaaaagact
    30961 tcaaaaagag ttaggtatta ctactttata tgttactcat gatcaagagg aagccttgac
    31021 tttatctgat agaattgcag tctttaacaa tggatacatc gaacaggtcg gtacaccagt
    31081 agagatttat cataattctc aaactgaatt tgtatgtgat tttattggag atattaatgt
    31141 tttgaccgat gaaacagtcc acgaagtatt actgaaaaat acaagcgttt tcttagaaga
    31201 taaaaaagga tacattcgat tagagaaagt tcgattcaat cgtgaaactg aacaagattt
    31261 cattctaaaa gggacaatta ttgatgttga gttttctgga gttacaattc actatacaat
    31321 aaaagtttct gaaagtcaga ttcttaatgt aacaagtatt gatagtcagg ctgctattag
    31381 atctgtcgga gaaagtgtgg aattatttat cacaccatca gacgttctgc aattttaagg
    31441 aggtgcagta tgcgtcataa attaaattta aaagattggc ttattcgttt agggttaatc
    31501 tggttcttag taacatttat tatttatcca aactttgatc tagtagtgaa tgtatttgta
    31561 aaaggaggag aattttccct tgatgctgta catcgtgttc taaaatctca gagggcactt
    31621 cagagtatta tgaacagttt taagttagca ttttcactca ttattacagt taatgtcgta
    31681 ggtattcttt gtgttctatt tacagagtac tttgatatta aaggtgctaa aattttaaaa
    31741 ttaggttata tgacctcttt aatttatgga ggagtggttt tagcgactgg atataaattt
    31801 gtctatggtc catatggatt gattacaaaa tttttacaaa atgttatccc ttctttagac
    31861 cctaactggt ttattgggta tggtgcagtc ttattcatta tgacattttc aggaactgct
    31921 aatcatacat tgtttttaac aaatacaatt cgaagcgttg actatcacac tattgaggct
    31981 gctcgaaata tgggagcaaa accatttact gttttccgaa aagtagtgtt accaacctta
    32041 attccaactc tatttgcact tactattatg gtttttctta gtggtttatc tgcagtagca
    32101 gcacccatga ttgttggtgg taaagaattt caaactataa atccaatgat tattacattt
    32161 gcagggatgg ggaattctcg tgatttagct gccttacttg caattatttt aggtattgca
    32221 actacaattt tgcttactat catgaataag atagaaaaag gtggaaatta tatttctatc
    32281 tctaagacta aagcgcctct taaaaaacaa aaaattgcgt ctaagccttg gaatatcatt
    32341 gctcacattg tagcatatgg attgttcaca gttttcatgc ttccactaat ttttatagta
    32401 ttatactcat ttacagatcc agttgcaatt caaacaggta acttaacatt atcaaacttt
    32461 actttagaaa attatcgctt attctttagt aatagtgcgg cattctctcc attcttggtc
    32521 agctttattt attctattat tgctgcgaca acagcaacaa ttctcgcagt tgtatttgct
    32581 cgtgttgtca gaaaacataa atctcgtttt gatttcttat ttgaatatgg tgctctactt
    32641 ccttggttat taccaagtac gcttttagca gtaagtttat tatttacttt taatcagcca
    32701 caatttcttg tcttgaatca gattttggta ggtagtttgg taattctact tattgcatat
    32761 atagttgtaa aaatcccatt ttcttataga atggtacgtg ctattttatt tagtgttgat
    32821 gatgagatgg aagatgcagc aagaagtatg ggtgcttcac ctttttatac tatgatgaag
    32881 gttatcattc catttatttt accggttgtt ctctctgtta ttgctttaaa ctttaactct
    32941 ttattaactg acttcgactt atctgtattc ctttaccatc ccctagctca accattaggt
    33001 attacgattc gatctgcagg tgatgaaaca gcaacatcta atgcacaagc tctggtattt
    33061 gtttatacaa ttgttctgat gattatttct ggaacggtat tatacttcac acaaagaccg
    33121 gggcgtaaag taaggaaata atcatgacag ccactagtct tgggttatca aatattgaaa
    33181 tagttgtcag gattgtttta tcagtagtca ttggtagtat aattggttta gagagaggga
    33241 gcaaatccca gcctgcaggc atccgaactt atagtattgt ttgtctagct gcatgtttga
    33301 ttatgatgac gaatgaatac gtatcttata aatttgggac aggagatcct acacgattag
    33361 gagctcaagt tatatcaggt gtgggttttc taggcgctgg aacgattctt attacagata
    33421 aaaagaaaat tacaggtctg acaactgcag caggcatttg ggcttcggca ggaattggat
    33481 tagctattgg agtaggtttt tatgagggag ctcttttagt agccatttct gtttggggtg
    33541 tgatatccat gttccaacca ctaaaaaaat atctacaaaa tcgttctaaa atgattgaat
    33601 tgtatatagt ggttaaatct acagaagcct ataatcgtgt attggtttat tgtgcagaaa
    33661 atggtatcag aatgaccgat tcaagaacag cgtttggaga tgttaattct gacagaattg
    33721 aatactttga tgttccagat aaaaaaatag cgtcatttat tactctggaa ttatcaggta
    33781 gatttgaaca tcttcgactg atggaagaaa ttgctaatat tgtaggtgtt atttatgtcg
    33841 aagaaattag ctgaaattta gtaaacaaag ggacagatgt ttttgtcctt ttgtttttta
    33901 gatgttttaa tcatctaatt tttgagtaga tttttgctca gaggttttta tgaaagatta
    33961 taaaatcaat tttgatttag gtaaaataga atattttgat aataattgtt tgatacaagt
    34021 atacaaattt atttcttttt atgatatttg tgaaatggtg tttgcctttc atttacctcc
    34081 tgatgagttg ataacaaatg ttatctttaa agaaaaaatt aactctatgt taaaatgtta
    34141 cattgacagg ctattatatg tttttataaa tcctacacat tttactgaaa aagttaatct
    34201 acaattttat ggcagttttt tctcatatga atttatttgt cgtgaagttg gaaacattct
    34261 taaaaataaa ggtgtgaaat gcaatttaaa tttttttgaa ggggaagaat atttgtaaaa
    34321 ttaattttgt gaatttgtgg atcttaaata atttactaaa ttctcttgtt aaaaaaaatt
    34381 aaatattgta tagtaatatt agaatgttcg taatggagga ctgaaatgaa aaatataaat
    34441 gggaaaaagg taactattta tgatattgca cgtttatcag gtttttctcc aaaaacagtt
    34501 tcacgagtta ttaatggtgg agtaaatgtt aaagaagaaa cttatcaagc gattcaaaaa
    34561 gttatagagg aattgtcgta tattccaaat gcgtatgcaa aaaatttaac taaaaaagaa
    34621 gctataaata tattgatttc tgtaaaaaaa atcgactctt ttcctttaat ttggtttcat
    34681 acgctgttag ataaagtgtt acggacgtgt aaagaatttg gtgttaatgc tatagttgag
    34741 tactttggag aggaggatac aattagtaat tcaattatat caagcacagg tagcctagta
    34801 gatggtgtta ttgtttttta tgaaagtgta gatgatatca gaattcagta tttaaagaag
    34861 aaccatatgc cttttcttgt tttcggtgaa tctcaaacgt ctggagtagt ctatgtatct
    34921 aataataatt ttcaagctac ttatgatatg atgaaagctg taactgaaga aaaatttaaa
    34981 aatatgtggt tgcttatggg aggagaatcc catgttaata aggatcgtga aagaggtgtg
    35041 cgttcttttc tgaatgataa aaattacttt atggatttaa aagtcattta tggcttatct
    35101 acaattgatt cagtttattc ttatgcaatg cagcacttga ctacccaaaa ttatccggac
    35161 attatttttg tttcaggaga tgaaaaggtt cagggcttga ttcgtgcgtg ctatgagaaa
    35221 ggaattctta ttccagatga tatttctatc attggatttg ataatattcc tatttctcag
    35281 tattatactc cagctttgtc tacaattgct cccaattatg ttaaattggc taaagaaatg
    35341 atagaaggtg ttttagcaat tattaaaggg gaaagtgtca catctgttga agtttctcct
    35401 aaatttgtta ggagacagag tttctagtat tgtttaattc ttgaaaatcc tagtggaaaa
    35461 gatggagtgt tctaaaataa gttctgttta gcctccattc agtttctatt gagttggatc
    35521 caatttctaa caagtgggac atgttcatgt tcgatctaag gaagacatgg tcacattcga
    35581 atgatatttt caaaaaaatc gtaaaaaagt cttgacaaag aaaaaacaaa gtattaaaat
    35641 aagttcaaca aatcagaaaa gtaactattt ttgatcttca gggagcctgt ggtggttgtg
    35701 aataggtggt tggaagtagt gaaagtgggc tgattttgaa aatgaatttg aaacaatgaa
    35761 aattcggtgc gcacacctta cagtgcagct tgttgttaaa caaggcagag atgtaaaggg
    35821 atagtccctt tataattgag gtggcaccgc gttaccaacg ccctcacacg gaagtatatt
    35881 ctgtgtgtgg gcttttttct atccgtcgtt tggtttatct tttattaggg ccttaagtcg
    35941 ctttgatgaa cttgagttct atctacagct ccttgcctac tactaaaagc aaacaaaaag
    36001 gctggactaa tacgaaaaaa gctagtaata ctcaatgaaa atcaaagagc aaactaggaa
    36061 actagccgca ggctgctcaa aa
//
LOCUS       DBERXF010000021        33208 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.21, whole genome shotgun sequence.
ACCESSION   DBERXF010000021 DBERXF010000000
VERSION     DBERXF010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.21"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(372..521)
                     /locus_tag="ACL8JK_001135"
     CDS             complement(372..521)
                     /locus_tag="ACL8JK_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
                     /protein_id="HGS1786030.1"
                     /translation="MEKFNFKNNIGQENKLLQIEIYKFTNFCKLQNYTSVNIFSKDIF
                     EAIVN"
     gene            486..605
                     /locus_tag="ACL8JK_001136"
     CDS             486..605
                     /locus_tag="ACL8JK_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HGS1786031.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(701..2047)
                     /gene="glnA"
                     /locus_tag="ACL8JK_001137"
     CDS             complement(701..2047)
                     /gene="glnA"
                     /locus_tag="ACL8JK_001137"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGS1786032.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTVIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="ACL8JK_001138"
     CDS             complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="ACL8JK_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HGS1786033.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYENQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(2517..3044)
                     /locus_tag="ACL8JK_001139"
     CDS             complement(2517..3044)
                     /locus_tag="ACL8JK_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGS1786034.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(3180..4376)
                     /gene="pgk"
                     /locus_tag="ACL8JK_001140"
     CDS             complement(3180..4376)
                     /gene="pgk"
                     /locus_tag="ACL8JK_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGS1786035.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(4466..9484)
                     /locus_tag="ACL8JK_001141"
                     /pseudo
     CDS             complement(4466..9484)
                     /locus_tag="ACL8JK_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
     gene            9777..11408
                     /locus_tag="ACL8JK_001142"
     CDS             9777..11408
                     /locus_tag="ACL8JK_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HGS1786036.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(11841..13448)
                     /locus_tag="ACL8JK_001143"
     CDS             complement(11841..13448)
                     /locus_tag="ACL8JK_001143"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGS1786037.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(13838..14425)
                     /gene="rpoE"
                     /locus_tag="ACL8JK_001144"
     CDS             complement(13838..14425)
                     /gene="rpoE"
                     /locus_tag="ACL8JK_001144"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGS1786038.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(14553..15002)
                     /locus_tag="ACL8JK_001145"
     CDS             complement(14553..15002)
                     /locus_tag="ACL8JK_001145"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1786039.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNYASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(15007..15396)
                     /locus_tag="ACL8JK_001146"
     CDS             complement(15007..15396)
                     /locus_tag="ACL8JK_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HGS1786040.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(15424..16074)
                     /locus_tag="ACL8JK_001147"
     CDS             complement(15424..16074)
                     /locus_tag="ACL8JK_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGS1786041.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIR
                     GDLPDYLTILFRSLTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKTPVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(16064..16627)
                     /locus_tag="ACL8JK_001148"
     CDS             complement(16064..16627)
                     /locus_tag="ACL8JK_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS1786042.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGPVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(16792..17026)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(17080..17583)
                     /locus_tag="ACL8JK_001149"
     CDS             complement(17080..17583)
                     /locus_tag="ACL8JK_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HGS1786043.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALHQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(17776..18606)
                     /locus_tag="ACL8JK_001150"
     CDS             complement(17776..18606)
                     /locus_tag="ACL8JK_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS1786044.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATIFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(18591..20273)
                     /locus_tag="ACL8JK_001151"
     CDS             complement(18591..20273)
                     /locus_tag="ACL8JK_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1786045.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLISLLNQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHCPVDRIV
                     LINDGRILFNGSTDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLYIS
                     KGQVQLRTELVKETPELQSLFRLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKALSSFIQTEGRYLWEGQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEQEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQQGHTIVMITHDMQLMLDYSDRALVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(20375..20632)
                     /locus_tag="ACL8JK_001152"
     CDS             complement(20375..20632)
                     /locus_tag="ACL8JK_001152"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786046.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(20639..21187)
                     /locus_tag="ACL8JK_001153"
     CDS             complement(20639..21187)
                     /locus_tag="ACL8JK_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HGS1786047.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(21202..22050)
                     /locus_tag="ACL8JK_001154"
     CDS             complement(21202..22050)
                     /locus_tag="ACL8JK_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HGS1786048.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     DQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            22238..23587
                     /gene="trkA"
                     /locus_tag="ACL8JK_001155"
     CDS             22238..23587
                     /gene="trkA"
                     /locus_tag="ACL8JK_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HGS1786049.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            23591..25030
                     /locus_tag="ACL8JK_001156"
     CDS             23591..25030
                     /locus_tag="ACL8JK_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGS1786050.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKMVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(25155..25556)
                     /locus_tag="ACL8JK_001157"
                     /pseudo
     CDS             complement(25155..25556)
                     /locus_tag="ACL8JK_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS alpha-glucoside transporter subunit IIB"
     gene            26964..27248
                     /locus_tag="ACL8JK_001158"
     CDS             26964..27248
                     /locus_tag="ACL8JK_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786051.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            27241..27489
                     /locus_tag="ACL8JK_001159"
     CDS             27241..27489
                     /locus_tag="ACL8JK_001159"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786052.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            27585..27803
                     /locus_tag="ACL8JK_001160"
     CDS             27585..27803
                     /locus_tag="ACL8JK_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786053.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(28171..30495)
                     /gene="pflB"
                     /locus_tag="ACL8JK_001161"
     CDS             complement(28171..30495)
                     /gene="pflB"
                     /locus_tag="ACL8JK_001161"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGS1786054.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            30844..31905
                     /gene="dinB"
                     /locus_tag="ACL8JK_001162"
     CDS             30844..31905
                     /gene="dinB"
                     /locus_tag="ACL8JK_001162"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGS1786055.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAENFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            complement(32052..32897)
                     /locus_tag="ACL8JK_001163"
     CDS             complement(32052..32897)
                     /locus_tag="ACL8JK_001163"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGS1786056.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
BASE COUNT         9833 a         7129 c         6155 g        10091 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 aacctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt caggattttc
      181 cccttgacaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattaa tttctagaaa tttttagcag atgtagtgta
      361 ctattctagt ctcaatttac tatggcttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagta aacttgtaga tttcgatttg aagtaacttg
      481 ttttcttgcc cgatattgtt tttgaaattg aatttttcca tagtgactcc ttgattttct
      541 tctacacgtc tgatgataaa tctaattcgc aaaagagtca agaggatttt tcgaaaaata
      601 aatagcgacc gaaatcgcta ttttaagggt tataggtatt tgatggctta gactgctgtg
      661 tgactgttta cccacaggca atctttcttc tatattagta ttagtaaagg tctaaataat
      721 tatcaatttc ccattgtgaa acgaaggttg cataacttgc ccattcgatt cgtttggctt
      781 caaggaagct agtgtagatg tgatctccga gagcagcttt aaccacttca tcttctgtca
      841 aagctttcaa agcgttgtga agagttgatg gaaggtctgt aataccagct tccttgcgct
      901 cttctgctgt catgatgtag atattttctt cgataggagc tggtgcttcg attttatttt
      961 caataccata caaaccaact tccaaaagaa cagccatagc aatgtaaggg ttcgccattg
     1021 gatccactga acgcaactca agacgagttc ccataccacg tgaagcaggt acgcgcacaa
     1081 gtggcgaacg gttacgacca gcccaagcaa tgtaaacagg cgcttcataa cctggaacca
     1141 aacgtttgta tgagttaact gttgggttca tgatgacagt atagttgtaa gcatgcttga
     1201 tcaaaccgcc taggaaatgg taagctgttt ctgacaactg cattcctttt ggatcatttg
     1261 gatcaaagaa ggcgttattt ccttctgcat caaacaagga catattacag tgcatacctg
     1321 agccagcaat accaaatttt ggcttcgcca taaatgttgc gtaaagtccg tgtttgcgag
     1381 caatggtttt aacaacaagt ttaaagattt gaatcttatc acaagcacgg agaacttcat
     1441 cgtacttaaa gtcaatctca tgctgtccaa ccgcaacctc gtggtgactc gcttctactt
     1501 caaatcccat tttggtcaag acattcacaa tctcacgacg tgtgttgtcc gcaaggtcag
     1561 taggtgccaa atcaaagtag ccacccttgt cattcacttc aagtgttggg tccccatttt
     1621 catccaactt aaataggaag aattctggct ctggaccaag gttgaaggat ttgaatccaa
     1681 cttcttccat gtgacgaaga gctcgtttca aattaccacg agggtcaccc gcaaatggtt
     1741 caccttctgt tgtataaaca tcacagatca gacctgcaac acttccattt tcatctcccc
     1801 aagggaagac tgtccatgta tccaagtccg ggtacaagta catatccgac tcattgatac
     1861 gtacaaaacc ttcaatagaa gatccatcaa acataacctt gttcgacaag accttatcta
     1921 actgttcatc tgtagcagga atttcgacgt ttttcatggt tcccaaaata tctgagaaca
     1981 taagacgaat aaaggtaaca tttttttcct tgacttcacg acgaatatct gcagctgtga
     2041 ttggcataag ttttctcctt aatctatgac tacttgcggt tgcctaaccg cgaccaaaag
     2101 gtgactgtac tgaagcaaaa cgcccctgtt ggaggagttc attgtgaagt gcacgacgta
     2161 cttcagtctg actaaccgct ttcttggatt tcgcttcacg ttcagcatat tttttcttaa
     2221 tggcagcgat attataacct tcagagatat aatctttgat ttcaagcaga cgatccatgt
     2281 cattcaagga atacatgcga cgatttcctt cgtttcgatc gggcttgatc aactcttgat
     2341 tttcataata acgaatctga cgcgccgata gatcggtcaa cttcataaca ctgccgatag
     2401 gaaaaacagc catatttcgg cgaaattctt tttccttcat ttacaatttc cttctttctg
     2461 tctattatag tctaaaaaaa gacaaacgtc aattaataat gttataaaat gtaacattat
     2521 ttttcttttt tctctaaaaa gagacgaata cgatcaatat cgtaatttac gataattgcg
     2581 acaaaaactc ccataaatgt ttctaataca cgcacaaaca cgtacaaaat tgtctcacca
     2641 cttggaattg atagggtaat aattaacata gctgctacac caccaataac ccctgctttg
     2701 ttattcatgg ctacatttgt cataatggtt aacatggtgc agattggaac aactaccaag
     2761 gtcacccaaa aggcttcgtg gaaaaaggta tttaataaga agaagaccaa ggcatagagt
     2821 ccaccgatac tatttcctag aatacgcgaa gtcccaaaat gaacactctc atcaaaactc
     2881 tccctcaggc taaaaacggc tgtcaaagca ccaatttgaa gacctttcca gccaaaaaag
     2941 ccaaaaatca agagaactag aaaaacagca atacctgttt taaaggttcg cataccaagt
     3001 ttgaactggg atttatcgaa tttatatttt ttaaaataac tcataatctc aactttctat
     3061 ttccatttta tcataaatcg gtgattttta tgagtaatag ttgagaggaa gcgtttttat
     3121 tttaagcaaa agaaaagagg aactttcatc cctctcttct ttgatttatt tataaaatct
     3181 tatttttctg tcaaggctgc aagtcctgga agaaccttac cttcaagaag ttccattgat
     3241 gctccaccac ccgtactaat ccatgagaac ttgtctgcac ggccaaggtt aatcgctgcg
     3301 gcagctgagt caccaccacc gatgattgat ttaactcctg gttgtttcac gatagcgtcc
     3361 atcacaccga ttgtaccagc ttggaaatct gggttttcaa atacacccat aggtccgttc
     3421 catacaactg ttttggcacc agtcaaagct tcgtcaaatt tggcgataga ttttggaccg
     3481 atgtcaagac caaggaagcc ttcagaaact gcttcacctt cagtgtcacg cacttcagtg
     3541 taaccagcaa atgcgttagc ttcttttgag tcaactggca agatcaattt accatttgct
     3601 ttttcaagaa gagctttcgc aacatccaat ttgtcttctt ctacaagtga gttaccgatt
     3661 tcgatacctt gtgctttgta gaatgtgtaa gtcatcccac caccgataag gactttatca
     3721 gctttttcaa gcaagttttc gataacaccg atcttgtctg aaacttttga accaccaagg
     3781 atagccacga atggacgttc tggagtttca actgcttctt ggatgtaggc aatttcgttt
     3841 tcaagaagga aaccagcaac tgctttttca acgtttgctg agataccaac gttagatgcg
     3901 tgtgcacggt gagctgtacc gaatgcatcg tttacgaaga taccatctcc aagtgatgcc
     3961 cagtatttac caagttcagg atcgttttta gattctttct tgccgtcaac atcttcgtaa
     4021 cgagtgtttt caaccaagag aacttgtcca tcttcaagag cgttgattgc cgcttccaat
     4081 tcagcaccac gagtgacacc tgggaaaaca acatcttgac caagttttgc tgccaagtca
     4141 gctgctacag gagcaagtga tttaccagct ttatcagctt cttctttcac acgtccaagg
     4201 tgagagaaaa gaattgcacg tccaccttgt tcgatgatgt acttaatagt tggaagagct
     4261 gctgtgatac ggttatcgtt agtgattacg ccatctttca atggtacgtt gaagtcaaca
     4321 cgaacgagga cttttttacc tttcaagtca acgtctttaa cagtaagttt tgccatgtta
     4381 caaaaactcc tttatttatt ttattagaaa ctattatatc acactttgga aatataagga
     4441 aagatttcac aagatttttc gatatttaat ctttatcttc tcttttccgt ctcaaggtca
     4501 aggctaaact agcaagacca aggctggcta agcctgctat tagggcttca ttagcatcag
     4561 ctgttcctgt atttggcaat tgtttgcttg cttcttctga tttaactgct gtattttgag
     4621 ctggtttttc ctgtgtagct actactgctg gtactgtttt tacttttgtt ccaatttcaa
     4681 caatttctgg aatcgcttct tggatgactt ctgttgaacg aagacgacgc tgaccgtttt
     4741 cataaacttc aaagacatgt cttaacagtc catctcgtcc ctgtatgatg actcattgtt
     4801 ccccaactag catctcagca ttttcatgct cttgacgatg aaaggcaacc ttttcctctt
     4861 gaacttccaa tttaggagcc ttttgttgat cagaagccgg ttgataagta ggttttggaa
     4921 ggactttgtt ttgtggtgct ggtttagcag gttgtggttt ttcagcagat tcataaacaa
     4981 aggcataatg agtaaagtga ggtgctgtaa agataacatg actatccgtt tgttcaaaag
     5041 tcaattctac tgcctctttg ccttcaggta agaaaaatac tttcttaact ttcttatctt
     5101 tttcaattgg gattttcaca atagaagcat aagagagatc aacatcttga cctttttcat
     5161 ccaaaccttc tatttcaaag acatgagcat cttctccagc aaagtatttc ttctcttcag
     5221 cacttgcttg aacacgctct actttcaaac ccttgatgac agtcttctct ttatttgaga
     5281 agtgtacttc aacacctgtt ttactatcag aaaagactgc tggcttgtct tctttcaata
     5341 aagcaaccag atcttttaga ctctgtttcg ctgttgtaag cccttctgga ctcaaatcta
     5401 ctttttcaac caaggccttg tttttctcaa gaagcggagc tagagcagaa cctgaaggat
     5461 ggtttggttt ggcagccaag agttcttgaa cctcacctgt taaacgatca agctctgtct
     5521 tttcttccgt aaatttctct tgaccattca gagctttatg agcttctgtc aatttattaa
     5581 gtcggtcatt gacttgatct tgggtgctag tttcatggtc tttcaacact tgttcggccg
     5641 cttcaattgc tttcaagaaa gcttctttta cttctggtga agcaaagtta tagaccacct
     5701 tgttcttagc agcttcaact tctgctaatt tctgtttgag gtactcatcg ttcaatgctg
     5761 cttttggaga taccaaaaca tcaaagttga cttcatgacc ttggtaacga agcgtcaagg
     5821 tttgacgacc agtcttttga gcatcataac cagaaatttc aactccctta tcagtaaagg
     5881 aatgttcttc catggtgtca ttgctataag ccactgcaaa gcgtccttca gacaagtcta
     5941 agctatcacc aactaggtaa tcttttttcg gttcctgact tacttcaatt cccaaaatag
     6001 ttttcggact tgcttcgtct tggccagtga cagtcactga caaattagca tttaccggtt
     6061 gtcccaaata ttggagagta agattctgtt ctcccttatg atgcgtatca aaacctgata
     6121 ctgatacacc tgcgtgagtt aggcgaatga gttcgtcctc agttcctcct tcatactgaa
     6181 ctcgaagaac accacctcta aggtccaaat cctccccttc ggcgtagctt gttttcttag
     6241 gtcctgtttc taggctgact gacttgattc ttctgtcatc ttttggaacg gaaactgcta
     6301 ggacattact aatttccttg cctggcaact gggtacgata ataaagaaga ccagattgat
     6361 ttgtcaaatc caatggtgca cttgctaggt ctcctccaac ttcgctcttc aaggttgcga
     6421 gtggagtttg agaatttgga ttatcataaa cggtaatagt tgctccagcc ggtacatctg
     6481 caaagccaac ttgtaccttg ttattgccta gagaacgggc tgcagccttg gccatcggaa
     6541 tattgacact ctcagtatca agcttttcat acattttcca gttatagata cgaatagcct
     6601 tccatggagt tccattgtca gaagtgacaa cattcaagcg ccagtcttga gcagtgattg
     6661 gtttatcaag agtgatatct gtcacgtgtg ctttgttgcc acggacttcc ttggctagct
     6721 tccactcacc atctgcatct ttataataaa ggtcaaagtc tttggtgttc atcaagccat
     6781 cgttaacaga ctcaccacca gcccctgcat gatccatgac ccatctaaca acggtacgtg
     6841 gcttggtcaa acgaatatcc acactaccac tcaactgagc tgaagaccat ttatctgaca
     6901 agctagtaat ggtaccgttc aacatacctt caataccttc tccaccttca gtcttaggga
     6961 aagtactatc aataactgtt gcacctggaa cgatattttc agctagtggt tttggtaggc
     7021 tggtatcttt tacagtcata ccccaatcaa aggttgtggt tgcagcttct gaacgaactc
     7081 catttttacc gactgctaca accttcagtt cttgagttgt accctgagca cttgctgagc
     7141 ggctaacttt tggtagataa atagttgtag aagatgagcc agttaataat ttccagctgt
     7201 ctccatcttt ttcataaact tcatagaaat ctgcatcctt gttgccttta aattgcacaa
     7261 ctgcttccgc ttcttgggca tttttaagag attgtttcac tacagaaaag cttgtcggcg
     7321 attgtggctc ttggtgattg tccgagatag ttaattgtcc gaggttgaac tgataatctt
     7381 ttacagcacc ttcatgctcg aaaaatagtt tgactgcata gatggtttta cccgctagtg
     7441 agctgagatc aaattcttca tttgtccagt tgtcagaaag ggttagctct ttccatgcat
     7501 ctgcatcatc gaatttgtag tctgaagttg tagagaatgc catataaact ttagaacctt
     7561 ttcctccctt gtgggcaaca cgaagtttgg tcttctcagt tacttctaac ttagtagaat
     7621 aaagtctcac atcctgaact gtcttaccgg ctacatcacc agagaattta agggaatttc
     7681 cgccattata ggcatctgta aaatcatatt ctgcacgaag tttttcccct gttgaagtct
     7741 gccaccagcg ccatgttgga agaacacctg atactgaacg ataattccac tcagaatcct
     7801 tagaaacctt accatctacg aaccattttt taccatgacc tgtattaaaa gaagtagtaa
     7861 aagtattacc taccgctggc gtacggtccg caactaggtt agcaatacca taccaatctt
     7921 tgtcacctgg tttttggcca gtggggtctc cttgataacc tgtaaagaag atatcttcat
     7981 ttttatgata atcttcacca gtttttccta aacttgtaat ggtatctggg gcaaataaac
     8041 caagagaaag gcgcaatttc ccattttcgt ctaaaatgtc attccactta acctttgtct
     8101 tgtaggaacc accctgttgc aattccaaac ctgcaaatac atcataagga ttacgaccaa
     8161 tccagttggc agttgcaata gtgtaatcat ttttagcctt atcccagtta aagttagcaa
     8221 agaagttatc tgccggaacc ttatctcctt ctggttgcat gaattggtag ttgtattctc
     8281 ccaaaccatc ttgatggtaa cgtccatagt tataggtcat ggcatcatac caagaatact
     8341 tgattggatg gtttacctta gcagcatatt ccttgctata gagcataaac tggcgcatct
     8401 tttctccaag aggtttaacc aaatctccag ttgtttcttg gttgatgaaa tagccatcat
     8461 agccataata ctttgccatg tctaccaatt tacgagcaat tgggaagcta ccatctgcgt
     8521 cttgcttcaa agcttcagca aatctttctt gatctgcaat actattagac cagttgaaga
     8581 agagtgtacc gtatacagga accccgttac ggtgacctgc atcaataacg tcaggagttg
     8641 gtacgagacc ttcccagaag accattgaat ctagatattg ccaatagtca aaagcatagg
     8701 ccttgaactc ttctccacca acagaagcat ggtcttttgc tttagaatta gtgtttgata
     8761 aggcttgaac ttttgcttcc ttgctagctt tttcattgac taaatgacct gtccgacgtg
     8821 aagcgaggac aacagatccg cggttaatag catcatcttc acgagcacct ggttcccatt
     8881 ttaacaattc ttcccaagaa ttaaatttga tttcctttgg ttttaatgtt ttttctgtat
     8941 ttttagggac atctggctgg acttcttttt cagtcttatt agcttcttct gctggtttag
     9001 actcatcccc ttggttagtt gcttcgggct ttgcttctgt ttccttgtca gacttaggtt
     9061 ttgcttctgc agatggtgtt tctgcaacca cctcacttgc tttttcctct ggtttagctg
     9121 cgctagctgc ttctgcagtt tcagtagttg cagcttcatt gcttgctggc gaagcagttt
     9181 cagtagttgc agcttcattg cttgctggcg aagcagtttc agatgctatc gctactcctt
     9241 ctgccttttc tagcttgttt tctctagcat gttccccttc attctgctta tcagcttcat
     9301 tggtcgaatg ctcactctct cctgaaacaa gctctgtatt agctccgcta ttttcaggaa
     9361 ctgcagtttc ttcagccaag gctggaccag caaataaaac agcaccaatc atcagcgagc
     9421 aggctcctac tgataactta cgaatactgt aacgacaacg tctttcaaaa aatggattct
     9481 tcattttctc ctcctaaaag attgattttg ttgttttcaa gaaagcgctt tgtattctgt
     9541 ggttttttat caaactctag aaccatgata atcacatttt tatcctaaaa catttttaga
     9601 caaaaaacaa tagctgtttt cacaaatcta aaataaggtt aaaaactctt aaaaataata
     9661 cacttatcaa ttataatttt cttttacaaa cttgacatta acacttgtta gatttacttt
     9721 tatcctttaa aatagaatag gagatattcc gcgattattt ttcggaggaa aaagaaatgt
     9781 ccattaattg gcaggaaatt ttatttcact ttttaggtgg cctggggcta ttcttatata
     9841 gtatcaagac catgggagac ggtttgcaac aagctgctgg agatcgcctt cgtttttaca
     9901 ttgacaaata tactagtaat cctttctttg gagttctggt tggtattggg atgactgctc
     9961 taattcagtc tagttctggt gtaacagtta ttacagtcgg cctggtcagt gccggtctct
    10021 taaccttacg tcaggctatc gggattgtca tgggtgctaa tattgggaca actgtcacat
    10081 cctttctcat cggttttaaa ttaggtaact atgccctacc tatgctcttt atcggtgccg
    10141 tctgtctctt ttttacgaaa aatcggacag tcaataatat cggacgcatc ctctttggtg
    10201 tcggtggtat cttttttgcc ctcaatctca tgagcggcgc aatggctcca ctcaaggatt
    10261 tacaggtctt taaggactat atgattgagc taagtaagaa tcctgttttg ggtgtctttg
    10321 tcggtactgg cttgaccttg ctaattcaag cttcttcggc taccattggg attttacaaa
    10381 acctctacgc cggcaatcta attgacctac agggagcttt gccagttcta tttggtgaca
    10441 atatcgggac aaccattaca gccatcattg cctctttagg ggctaatatt gcagctaaac
    10501 gggtagcagg agctcatgtt gccttcaacg ttatcggaac agtcgtctgc gttatttttc
    10561 tagttccttt tactgtcctg attcattggt ttgaagctac gctaaatcta gcaccggaaa
    10621 tgaccatcgc ctttgctcac ggaaccttta atattaccaa caccattgtc caatttccat
    10681 ttatcggagc tctggcttac tttgtaacca agattattcc tggagaggac gaggttgtca
    10741 aatacgaacc cttatatctt gatgaacatt tcatcaaaca ggccccatct atcgctctag
    10801 gaaatgctaa gaaagagctc ttgcacttag gaaactacgc tgctaaagcc tttgaccttt
    10861 cctataagta catcattgac ttggatgaaa aagttgctga aaaagggcat aaaaccgaag
    10921 aagcaattaa caccatcgat gagcaattaa cacgttatct cattgccctt tcaagcgaag
    10981 ctctcagcca aaaagaaagt gaagtgctta ccaatatcct tgattcctcc cgtgatttgg
    11041 aacggattgg agaccacacg gaggctctac tcaatctgac tgactatctt caacggaaaa
    11101 atgttgaatt ttctgatgcc gccttgaaag aattagagga agtttaccgc caaactagtg
    11161 actttatcaa agatgctctg gatagtgtgg aaaacaatga tattgaaaaa gcacgcagtc
    11221 ttgtagaacg tcatgaagca atcaataaga tagaacgtgt tctcagaaaa acccacatca
    11281 aacgtctcaa caaaggcgaa tgttcaacac aagctggggt caactttatc gacatcatct
    11341 cacactacac tcgtgtatca gaccacgcta tgaaccttgc tgaaaaggtt tttgcagaac
    11401 aaatctaaga accaagaagc tatccatcat aattggatgg ctttttactt tttcctaagc
    11461 aagactaggc tgaatgaaac tgaaagagta ttctgtagat atatagtata ttgaaactag
    11521 aatagtacac ctctatttct aaaacattct tagaaatcga tttgactgtc ctgatagaga
    11581 tgttcacatc ttatttcaat tcactataca atccagttcc taaaactttg ctagaaattg
    11641 atttggcttt ccgaattaat ttgttcaaat tttatttcat ttcaatatac tgataaatcc
    11701 attcactagc acagggcaag agggagtcgc tatttatttc aacggtagca ggtacataca
    11761 gaggactcct atctcagata tactgcaata tcatcgtatg caaaaaacct ctgagatttt
    11821 tctcaaaggt tctgattttg ctaattgctg ttctcaaccg ctgcagtaac aaaggcagtg
    11881 tagagttctt ctggtcggtt tggacggctt gacagttcag ggtgatactg acaagctaca
    11941 aagaatttat tttcaggaat ttccacgatt tctaccaaac gattgtctgg agaaactcct
    12001 gaaaagacaa aacctgctgc ctcaaactgc tcacggaagg cattattaaa ctcataacgg
    12061 tgacggtgac ggcgttgcac cacttcttga ttgtgataag cagcagcagc cttagagcca
    12121 cgtttcaact tagacggata aagtcccaaa cgaagggttc cacccatatc ctcaatatca
    12181 atctgatcac gcatgatatc aatgataggg tattttgttt ctggtgcaag ctctgcagaa
    12241 ttggcacctt caagacctaa aacgtgacga gcaaactcga tacatgtcaa ctgcattccc
    12301 aagcagactc ccaacattgg aacatcattt tcacgcgcat agcggatggc ttggattttc
    12361 ccttctgtac cacgttgacc aaaaccacct ggtacgatga tcccgtccgc atcagacaag
    12421 agttctgcta cattctctgc tgtcacatca ttggcattga cccaattgat tttaacttct
    12481 acatcattga catagccaga gtgtttcaag gcttcgacca ctgagatata ggcatcttgc
    12541 aactccacat acttaccaac aagggaaatc ttaacttgtt tcttgaggtt catgaccttg
    12601 tccaccatgg ctgaccattc tgtcatatcc gctgctggtg cgtctaattt caaatgatca
    12661 caaacaattt ggtccatccc ttgtgcctgc aagttcagtg gaatttggta aaggtgttca
    12721 acatccaacg attcgataac ggcttctggt gccacatcac agaactgggc cagtttattt
    12781 ttaattcctt gaccagctgg ctcttctgta cgaataacca acatatttgg ttggattccc
    12841 aagccacgca attctttgac agagtgttgg gttggtttgg ttttcatttc accagcagcc
    12901 ttgaggtaag gaagcaaggt tgtatggata tacatgacat tatccgcacc cacatctgcc
    12961 ttcatctgac gaagagcctc taggaatggc aaggactcga tatctcctac tgttccacca
    13021 acctctgtga taatgacatc agagtcggtc gttagagcgg cacgcttgat tttttctttc
    13081 aaagcatctg tgatatgagg aatgacttga acagttgccc caaggtattc tccacggcgt
    13141 tctttacgaa gaacttcact gtaaattttc ccagttgtca cgttggaata tttgttgaga
    13201 ttgatatcga tgaaacgttc atagtgaccc aagtccaaat ctgtctcagc tccgtcatct
    13261 gtcacaaaaa cttccccgtg ctggtaagga ctcatggttc ccggatcaat attgatataa
    13321 gggtcaaact tttgaatggt tactttgaga ccacgatttt tcaagagacg gcctagactc
    13381 gctgccacaa tccctttccc aatggacgat accacaccac cagttacaaa aatatatttc
    13441 gtagacatag attcctcttt ctaaaatgct caaggtcttg ttaactacga ggggatatag
    13501 aaaacaagac cctactaata agaataatct gggacgactg caccagattc acaactaata
    13561 ctcttcgaaa atctcttcaa accgcgtcaa cgtcgccttg ccgtagatat gtgttcctga
    13621 ctttgtcagt cttatctaca acctcaaaac agtgttttga gcagcctacg gctagtttcc
    13681 tagcttgctc tttgattttc attgagtata aaatacaaga agataacttc ttgaaaaaac
    13741 aaaaatagct ccctaagaac tagggagccc cgacctctaa aagaggtgcc caaacaatat
    13801 gatacctaaa aataggataa ttgtcaatag ctaactctta ttcctcgctg gtttcagcgt
    13861 cgtcatctga aaactcgtcg tcgtcttcgt tgagatccac atcttctccc aagtcatctg
    13921 gagcgatttc gttgatttct gcatcataag cttccacttc atttttttca tcatctggat
    13981 tttcatcatc gtatgaaaga gctggatctg cttcgtatgc atcttcgtct tctggatcat
    14041 ctgcattgta gtcaatggca tctgaatcac catccataaa ggcattgaca cgttttttct
    14101 tagcttttgg tgctacttca tcgtcgtcat tttcttcaag agcgatgatt tcttcgtcga
    14161 tttcgtccac accataccat gaacgaagac cccatttgtt gtccccaagt gagatgaagc
    14221 taccgtcaaa gttcaactct gtgtagaaca aaggcaaagc ttcgcggata tcgctgtttg
    14281 atgttccaag gtagttttga atttcgttta caagatcgct aaaatgcatc tcatgatcgc
    14341 gaccacgaag ttccaagata gcacgcgcta cctcaatcat agatagttca cttttttctt
    14401 gcccagcaaa tacttctaat tccaaagcgt ttctcctcat ttatactact atcgccagag
    14461 cgaacagact ctgacctcat tttatcattt actctttatt ttacgataat tttgcggaat
    14521 agtcaaaggt taagggggag aaagtggcag gattagacta attccaatat aaaactcctt
    14581 cctttttctg ttgctccatt ttccacaaat ccaagcgact tgaaacacct cctagaagca
    14641 taattgtagg tgtagatttc cttgactctc aattctttcc atccttttac tcgagccaat
    14701 tcaatcaaag cacttagaat cttttttcca agtcctcgat gttggtaagc ggaattccca
    14761 atcacaatgg ggagattatc ctgagatagt gtaatatccc caattggaaa ccattctccc
    14821 ttctccttga cttcaatcca aaaaagctca ccatgccgat ccaaatagga atacatggct
    14881 tccaaggtcg cttgactgta aggaagcttc accccatcta cgaggtaaac caagttcaca
    14941 tcctgatacc aagcaaaagc ttcctcacaa tgattgacct tataataagg aacaaaacac
    15001 aatgcactac cttttcaaca aaagagttgc tgcttgatta aaaccatcac accagttata
    15061 ccattttgct tcatacccat cttgagctag gatacgatct tctaaatcaa aaacagagta
    15121 aatctttctt tcctcgcaag cttgcgcata gagatgatat agttcatcac caccatctct
    15181 atcccactca gcagaaatcg tatcccgacc tgccaataaa gcctgataag ccctgtgatg
    15241 cccatctgta atcagcaaac aatctccaaa ggcaagaata ctgattggat cgacttggat
    15301 tgtttctgcc gactggtaaa gcatctgaat atcttgcaac ttcttttctg ataaatatag
    15361 ttgagtcgga tgaagatctg ctatattgac tttcatttct ttctcctcaa gggaattcga
    15421 tactcacttc tgtttgcctt taaatcgcca ttggaagcgg agcttgtcat agaagggaaa
    15481 ctcgataaac aggactccca agcccacaca gagactggca aggacgtctg atgggtaatg
    15541 aactcccaga tagactcttg ataccagcac actgactagg tagaggccaa ggacgatttg
    15601 tacgattttt ctccagactg gagttttaat tcgttgactg agaatgacaa tcagagtacc
    15661 taccatcaaa gttacagcca gagaatgccc acttgggaag gaaaatccct tctcttccac
    15721 cagatgtaag atagctggtc gtgggcgctg gtagatattt ttaaaggtca cgattaaaag
    15781 acctgccaaa gccagatttc ccagcatgaa gaaactttct atcttccatc gcttacgata
    15841 aaagacaaaa gctgtaatga caacccaagt gataatcact gggatatcaa tcagacgtgt
    15901 gagggatcga aaaagaatag tcaaataatc tggtaagtct cctcgaatgg cagtctgaat
    15961 cgattggtca aaattgacca acatttcagg gtaaaatttg accatatagc caagaataac
    16021 gaaaagtaaa agggcaaaac tgcccttcat taaaaatgtt tgtttatctt tcatagtgtt
    16081 ttaaggttgg tttcaaaagg acgtacaaca accagaatga aacggaaaag attacaccct
    16141 caatcaagtt aaaaggtaat accatggtca ttaggtagtt ggaaagtccc aaaatttttc
    16201 caatatcaaa gttagcaaac ttagcgtaca aaggaacagc ataaacatag ttgagaacca
    16261 acatggccaa ggttaaacca acagttccag ctagagagcc tagtaggaaa cgaagggttg
    16321 tccgttcctt tttccaaatc aaagcaaata cgatgacaaa aactcccaaa gctacgatat
    16381 tcatcggcaa accaatgtaa gtattcactc cttggctgtt aagaagcaat ttcaagagtg
    16441 agcgaagcaa gagcactcct agagcagcag gcaaatccat gaccaccgga cccacaagga
    16501 ctggcaagat actaaattcg atcttgagga aagatgccgc tggtaaaagc ggaaagtcaa
    16561 agtacatcag cacaaatgag atggctgata aaattgcaat ggtcgaaagt cgacgtgtgt
    16621 ttgtcataac aggttcctcc aattttctat aaaatcagaa gaagttggaa aggattcctc
    16681 tatctattct cactttttat atcccaaaag ttccctctta ctctattaaa gaaaaacaaa
    16741 gcaagtggtt acaatccggc tataaatcta tcaaaacaga caaagctatt ctttcgtctt
    16801 ctcccatcca gactatactg tcggttgtgg aatctcacca catcagcttg cgctcgcgga
    16861 cttctttaaa gagaaggaaa tagagatttt tcttttagac taggcgacaa gctgtaggca
    16921 taacttctgg ttaggcaaag cttgtcaaca aagtataaaa ggaaaagatc atttcctagt
    16981 taaagtcacc gccggtcggg aatcacaccc tgccctgaag actcttttat cataacaaaa
    17041 aacgcttgca agcgcaagca ttttgttcat tttcattttt tatttcaatt tatccacttc
    17101 ataggtatgg acgagctcaa gacctgcaaa gttctgctgg tgaagagcct catagacaat
    17161 catgcagacg gtattagaca cattgagact gcggacatgt tcatcattca tgggaatacg
    17221 gagagccttc tcaggatgtt ctcgcataaa atcttcaggt aagcccttgt cttcacgtcc
    17281 aaagagaaaa taatggtcct cgtcagtcga taaatccacc tcagaataga ctttttccgc
    17341 gaatttcgaa atcagataga gttttccctt catctgagat atgaaatctt ccaaactctc
    17401 gtaaaaataa atctctagct tatcccagta atccaatcca gcccgcttca tcttgcggtc
    17461 atcaatagga aagcccatag gcttgatgat gtggagggga gaattggtcg cagcgcaagt
    17521 acgcgcgata ttgcccgtat tttgtggaat ttgaggttca aataatacaa tgtgatttgt
    17581 catgacttgc ttcctttcac cattgcaaaa aaatagccac actgcccgga gtcaagctca
    17641 gcaaacagcg tggttaaggc atcgttaact tacctcacaa caggtttgaa gtaaatcagc
    17701 gaaactactt tcttagtata acactttcag aatcattgtc aatagaaatg acttgatttt
    17761 ttcaattttt tcaagctatt tccaagggtt gtaaaatcgt ccctgattct gcaagataag
    17821 tagtaaacta actactaaaa acaaggttgc caagagcaag gtaatatagt ctcctttttt
    17881 caaggcctga taactatacc atgtgcgttt tttctctttc ccaaagcggc gaagctccat
    17941 ggcagtcgca atggtatcaa tgcgttctag cgagctaaaa atcaagggcg taataatgag
    18001 cagattgcct ttgattcgtt gcataagaga agctttcttg gataattcca tcccacgcgc
    18061 ctcctgagac atcttgatag taaagaattc ttcctgcaaa tctggaatat agcgcaaggt
    18121 caggctgaca gaataagcaa tcttataggg cacaccaatt tgatttaaac tggaagcaaa
    18181 ctgactagga tgggttgtca tcaaaaagat aatagccaga ggaatggtgc aaagatactt
    18241 aatggccaaa tttagcagat aaaagagctc ctggctggtt agagtgtaga caccgattcc
    18301 ctgccaaatc acacttctct ctccataaag tccaacccca tactcgggag aaaagagata
    18361 gaccatcaaa acgtttaaaa cggcaaatat cgtcgcaaaa acggctacaa aggaaacatc
    18421 tttaaagcga atttctgata aatagaggag aaagactgaa aagatggcaa tcagcaagag
    18481 cattctggta tcatagctaa tcatggccgc caatgatacc agaatgaaaa agagaagttt
    18541 cccagctcct gacaagcgat gaatcacagt atctctatgc tggtaaccga ttaatttagc
    18601 ttgcatccct ctctcctttc tttgtaaaat gccgttaaat ccagtggatc cacatctagt
    18661 ttcttagcca agttaaagat ggaggtttct tttagattgg cttttactaa cagctcagga
    18721 tcgctcaaca gactggctgg aacagtatcg gcaatcaatt ctccatccac catgacaagg
    18781 gctcgatctg aataatccag catcaattgc atatcatggg taatcatgac aatggtatgc
    18841 ccttgttgat gcagttcttc gagaaattcc ataatctcag tatagttctt ctggtcttga
    18901 cccgcagtcg gttcatctag gaggataatt tcagcgccta agaccaaaat tgaggcaata
    18961 gtcacacgtt ttttctgacc aaatgacagg gcagaaatgg gccaattacg gaattcatag
    19021 agaccacaga ttttcaaggt ttcatagact ctcgtttcaa tttcctgctc gtccacacct
    19081 cgcaaacgga gtcccagagc cacctcatca aaaatcatat tggttgaaat catttgattg
    19141 ggattttgca gcacatagcc tactcgttcc gcccgctctg caacagaatc tccttttata
    19201 tcctgtcctt cccaaagata gcggccttca gtctggataa agctactcaa ggccttggct
    19261 agagttgact tccctgctcc attttttccg acaatggcaa tcttttcacc ctttttaata
    19321 tctaaatgaa gagattttaa aatcggtcta tcatcataag aaaacgacac gtcctctagt
    19381 ctaaagagtg actgcaattc tggggtttct tttaccagtt ccgtccgcaa ctgaacctga
    19441 ccttttgaga tatacaagtt atccagatct gctaattgtt cttccttgac taaatccaca
    19501 cccaattgac ggagagtggt gagataaagg ggttcgcgaa ttccattttg ggtcaacaaa
    19561 tcagtcgcca gtaactggtc agtgctccca ttaaaaagga tacgaccatc gtttatcaag
    19621 acaatccgat ccacagggca atgcagaaca tcctccaaac ggtgctcgat aataagggtc
    19681 gtcgtcccct cctccttatg aatctggtca atcaattcga taatatcctg acctgacttg
    19741 ggatcaagat tggcgagtgg ctcatcaaac aagagaatcg gactctcatc aatcaagaca
    19801 ccagccagac tgactcgctg cttttgccca ccagacaaat cctgaggacg ctgattcagt
    19861 aaagaaataa ggtccagctt ttcagcccat ttataaacac gacctttcat ctcatctagg
    19921 gctgtcacat cattttccag agcaaacgcc aaatcttctg ccacagacaa gccaataaac
    19981 tgcccatctg tatcctgcaa aactgtgcta accagatgag acttatcata gatgctcata
    20041 tcaaaggcta cttgaccctt tatcaaaaat tctccatatg tctgaccctt gtaaatattg
    20101 ggaataatcc cattcaaaca ctgacccaag gtagatttac ctgacccaga tggtccaaca
    20161 attaagactt tctctccctt gtaaatggtc aagtctatcc cttgcaaggt cggttcttgt
    20221 tgtgtttcat accggaaaga gaaatccttc cactcaatta tagcttcttt catcttactc
    20281 tcttcattcg cttcttagac ttctatttta tcataaatca agcccttctt gcagtctctc
    20341 ctcttaaaat cttagcgcca aaaagattcc tatcctagct tacttgccta actaatctat
    20401 aaacatcgaa aaagactagt tgcccagcct tccccatcat tttatactct tcgaaaatct
    20461 cttcaaacca cgtcagcttc gccttgccgt aggtatggtt actgacttcg tcagtttcat
    20521 ctacaacctc aaaaccatgt tttgagctga cttcgtcagt tctatccaca atctcaaaac
    20581 actgttttga gcaacctgcg gctaacttcc tagtttgctc tttgattttc attgagtatt
    20641 agtccttttt caaacttcct gcacgagttt gagttcctgc ataggcaagt aagagaagag
    20701 ttcctgcaat agctacagat acaccattgg caattcccgc aacaatccct tgtgcaaata
    20761 ctttttctgc cgcttcttga taaatcacaa catctccaag tggtgccaag acaccccaaa
    20821 caagggcatt tgcaagtagt tgaatgaggt taaaaataag aatatctttc cagtcaaaaa
    20881 caccattgat cactcgaacg tactttctaa aaagtcccac aactaaacca aagagtccgc
    20941 tagcgataat ccaagtccac catagaccat aaccagcaag agagtccttg attgcatgac
    21001 caatcaaccc gacaagcaaa ccgataatcg gtccaaaaat aatagaaagt agcgcttgta
    21061 ccgcatactg aagctggatg cttgtatttg gaacaggggt tggaatgttg atcatcccga
    21121 tgacgacaaa gagggcagcg ccaattccga cagcaacaac ttgtttaatt gtaaatttga
    21181 tttccatact attctcctat tttatccttc tattttcttt atttcaatgg tccaagatga
    21241 accgacacct acattatagg ccttggcaaa ggaaccttgg ttgatagcca aacctaaacg
    21301 atagagagag ttgatgtaaa ggatgggttg cccaattctc acatctgcaa atgatttgcc
    21361 atagacaacc tgattttgat agaccagcat atcagcatga tagatggtca cttcaaaacg
    21421 atcaccaaat tctggttcca gcttgtaaaa ttcttcccgt gtgatagagg tccaaagcga
    21481 accgaaacgc acatccagaa tatcaatggc tcccttcacc agatgatctt ctatgatggt
    21541 cgctacgact ggaagctcta caatctggtc cacactgagc tctggcccta cttcctcaaa
    21601 agtaatgtga ccactggcca gtttagcacc agtataggca tagacatcac gaccgtggaa
    21661 ggtataagaa tgctctgtgt tttgacgcct attggccacc tcagaaatct cacgaatggc
    21721 tacaatgcca acgtgtttct tgataaagga aagcgtccca ttatctggcg tgacaatgta
    21781 ttgatttttt gcagtcttgg caactacact cttacgtttc gaaccgacac ctggatcgac
    21841 aaccgataca aacgtcgttc cctcaggcca gtaatccacc gtctgaaaga gacgatagct
    21901 cccctcaaaa atattataag gcgtgatatc gtgcgtcaag tgatggattt ttaaggttgg
    21961 agactcttct aaagccactc caatcatagc cgataccgca ccatcaacca gaccaaagtc
    22021 tgattgtaat accagtaaat tattattcat tttatctcct tgtatatcct ttatcatacc
    22081 atatttcaga gaaagtcgct aatagctatt tcaattggtt agggtatagt tttaccttat
    22141 agcgaatttt cactaaaagc tcttgttatt agctagtagg tgcatttttt cttgaaaaag
    22201 ggtatgatag ttacatcatg aaaaagtagg ttttattatg aaaattatcc ttgtcggagg
    22261 gggaaaagtt ggttttgccc tctgtcgctc cttggttgca gaaaagcatg atgttttgct
    22321 gattgagcaa gacgaagctg ttctcaatca tattgtcagt cgctttgata tcattggtat
    22381 ccttggtaac ggggccgatt ttgccattct tgagcaagcc agcgtccaag attgtgatat
    22441 ctttatcgcc ctgactgagc acgatgaagt caacatgatt gcagcagttc tagccaagaa
    22501 aatgggagct aaagaaacta tcgttcgggt gaggaaccct gaatattcta actcttattt
    22561 caaggaaaag aatattctcg gtttttctct tatcgttaat cctgagctct tggctgcccg
    22621 cgctatcgcg aatatcattg acttccccaa cgccctgtct gtcgaacgct ttgctggtgg
    22681 acgcgttagc ctcatggaat ttgtcgtcaa gtccaccagc ggtctttgcc aaatgcccat
    22741 ttctgatttt cgtaaaaaat ttggtaatgt cattgtctgt gcgatagaga gggatcatca
    22801 aattatcatt ccaagcggtg acatgactgt acaggataaa gatagaatct ttgtcactgg
    22861 taaccgtgtc gatatgatac tcttccataa ttattttaaa tcacgcgccg tgaagagcct
    22921 tctcatcgtt ggagcaggta gaattgccta ttatctactt ggtattctca aagatagtcg
    22981 tatcgataca aaagtcattg aaatcaatcc tgaaatcgcc agcttcttta gcgagaaatt
    23041 cccaaatctc tacatcgttc aaggagatgg aaccgcaaaa gatatcctgc tggaagaaag
    23101 tgctcaacac tatgatgccg ttgcgactct aacaggagtc gatgaggaaa atctgattac
    23161 atctatgttc cttgacaggg taggtgtaca gaaaaatatt actaaggtca atcgtaccag
    23221 tctcctcgag attatcaatg cgcctgattt ttcaagtatc atcacaccta aaagcatcgc
    23281 tgtagatacg attatgcact ttattcgtgg tcgagttaat gcccagtatt cagaccttca
    23341 agccatgcac catctagcca atggccaaat cgaaaccctg caattccata tcaaggaagc
    23401 caataaaatg actgccaaac ctctttctca actgaaattg aaaaaagggg ttcttattgc
    23461 agccattatt cgaaagggca agactatttt cccaactggg gaggatatgt tggaagttgg
    23521 agacaagctc ctagtaacaa ccttgttgcc aaacatcacc aagatttatg acttgattgc
    23581 gaggtaagaa atgaataaaa gtatgattcg ttacctcctt tcaaagttac ttttgattga
    23641 agctgttctc ctcttggttc ctgtggctat cgctgtctat taccgtgaat cgagccaagt
    23701 ctttacagcc ctcttttcga ccatagggat tctcgtattg ttaggcggtt cagggagttt
    23761 acagaagcca aaaaatcaac ggatttatgc caaggaggga gtcttgatcg ttgccctctg
    23821 ttggatcctt tggtctttct ttggtggtct cccctttgtc ttttctgggc aaatccctag
    23881 ccttattgat gccttttttg aaattagttc tgggtttaca actactggag caagtatttt
    23941 gaacgacatt tcggttctca gccgttccct cctcttctgg cgaagtttta cccacttgat
    24001 tggagggatg ggagtgcttg tttttgcact tgctattatg gacaatgcca aaaatagtca
    24061 cctagaagta atgaaggctg aggttcctgg tcctgtcttt ggtaaggttg tatccaaatt
    24121 aaaaaacact gcccagatcc tctatctcct ttacatagcc ctcttttccc tctttgtcat
    24181 catctattat ctagccggta tgcctctcta cgatagtttt gtcattgcta tggggacagc
    24241 gggaactgga ggatttaccg tctataacga tggaattgcc cactatggta gctcactgat
    24301 tacctatctg gttagtatag gagttttggt ttttggggta aatttcaatc tctactacta
    24361 ccttatgctc cgtcgggtta aggccttctt tggagatgaa gagcttcggg cttacttggt
    24421 catcgtgctg gtttctacag gcttgattag cctcaatact ctctacctct acccagggtt
    24481 ttcaaagagc tttgaaatga ccttcttcca ggtttccaac atcattacaa caactggttt
    24541 tggatatgga gatattacca actggcccct cttctcccag tttatcctcc ttttcctcat
    24601 ggcaatcggt ggctctgctg gatcaactgc aggtggactc aagattattc gaggcctcat
    24661 cctttcaaaa attgccaaaa accaaatttt gtcaatccta tcgccccacc gtgttttgac
    24721 cctccatgtt aataaaatgg tgattgacaa agatacccag cataagattc tcaagtactt
    24781 tgtcatctat gctatgattt tgctagcgct tatctttatt gtcagcctag atagcaatga
    24841 ttttctggtc gtgaccagcg ctgtctttag ctgtttcaat aatatcgggc ctattctagg
    24901 aaccacttct agtttctcaa tctttagtcc catctcaaaa attctcctct cctttgcaat
    24961 gattgcaggg cgcttggaga tttacccaat cctccttctc tttatgaaaa gaacttggtc
    25021 taagagataa aatacaaaat ccctcttttt acaattgtga aagagggatt tttatattaa
    25081 aaagggggaa cgtttttaaa tccaagcctg tctgtaagca aagttcttac tcaaataaaa
    25141 gatggaaaaa cttactacac agcttggtaa tgctccaata caaattgtaa ggctttactt
    25201 ggattctttg ttaaatgaat atattccatt cctctggtag caactatctg aatacctaat
    25261 ctttctgcat ccaccttcat ctctctataa taactccgaa cttgtggagc cagaataatt
    25321 aaatcataaa cacccataat atcataatga gctccgtacg ctcctgaatt cgcaatcact
    25381 ctaacttctg ctaattgagc gccctcgtta attgcattgg ctaattacgc acttgttcca
    25441 gaccctgcac aaagaaccag tactttcaac tccttacttt ttattacatc tatctcacca
    25501 ggcattattt cacttgtatc ctcctctaaa ataatatcat ttgagcttgc aatatctata
    25561 acctgtagta aatatctcgt atttagacaa tatgaaaaca agacgacttc catataggaa
    25621 accgccttct cgctatgttg agtgatttat attaaaataa cttttcttct agctgcattt
    25681 tattattata aaaacattca tcataacccc cagaacttaa ataacaattt ttattcaaga
    25741 tacatactcc tagaataaac tttatatgaa attctcattt ttgtttttac aattctcctt
    25801 agttaaatct tgtttaatat atgttttaca tatagtattt agcgcgacat aatactgaag
    25861 tctctctcca aaaaacggtt atgcttcttt gaataggacg ttctcacaag aaaagcatct
    25921 tcacgtttca acttcatatg gctcaaaaac aatcaattga tgctaaaacc tgtacctaga
    25981 tgtttcggtt cataaaacca tgaaactgta aaagtggatg aaattgatag cgatagtcaa
    26041 atcaagaggc atcataactc taaaaagtca caatatataa gttcatcctc ggaaaaatat
    26101 cattctaatt gttgaaatgg atatataaac aggggtatta acattaaatg ctcatgaaac
    26161 aacgaataca ggtatcaaaa ctatgacaaa acaagtccct aaatttacta aagacactgc
    26221 tcaactttac acctgtaaat ggttgttgta taataaagtt acaaagatgt acgaccacac
    26281 tgttgtaaat catagtgttc gcgaatatat tactgatagc atttctacaa atacaattga
    26341 agaggctgga taggctttaa acgaaatatg tcagtgtttt ggcattccta gccttaatat
    26401 catttaaaga attgtataga taaaattttt tccaatacag agactcgtaa caactgcttc
    26461 atttttctac caacatattt aggaacagga taagatacaa gaggattaat ccataaatca
    26521 gttctatacc aatctaagat aaataagcta aaaaacaatt gataataagc aaatagattc
    26581 caaattttct ctatctgctc attttaataa acaatactag tgtaactatc cttccagtca
    26641 gaagcttgtc aaatcacacc gaaaattctt ctaaaattta tctcgttagg caatcaagca
    26701 aaaactcgac gatagtacaa acattatcat acaggattga cttcctaaat tatatacttt
    26761 agtaaggttt tcgtataaga aaaaagattc attttacatt tctaaacatt cttttctaag
    26821 atgaaaaaca gaatttttcg attgtgattt aaagcaacaa gaagattttc agtatcatcc
    26881 tatagatacg agctaattaa gaaaaactac attttcgaat ataaactaca ataatataaa
    26941 ctaaatttta taggaggaag acaatggatt ggtacgatta tatgatacag gcatccaaac
    27001 aatcacaatt caacgcaagc cattggtttc gctatttgcg aaaagttatt tttgaagact
    27061 attcttattt aacaaaccaa gatgtagaaa agttgctaga ctccaaagaa ctaacccgtt
    27121 ttcaaaaaat tagcttgaag tatgcctttc aagagcatac tccaactcat aaatatgtga
    27181 tttcattaaa taaacctgct aagttaacca atgttcaaaa attgatggag aaatacaaac
    27241 atggataaaa tgaaaccggt cttccaagcc ctaaataagg aattaattca ggaaaatctg
    27301 actttaacaa ttatctgtgt cgatggttat gtcttagaat atcatggttt acgtgccaca
    27361 caagatgttg atgcttttta tgaccaaaat cagaaaatca atgaaattat tgctcgtgta
    27421 ggaaaacagt ttaatcttaa catccacgaa gagttatggc tcaacaatca tgttgcaaag
    27481 caaatatgaa caaacaacct cccttaagtt tatgcgaatc cttgtactca tttgagaatc
    27541 tgaccgtttt agtagtccct attgagtatg tgttaggaat gaagatgatg agtatcagag
    27601 agcaggattt gcaagatatt ggtgcaatta ttaaatacaa aaactttcat tcaccattcg
    27661 atacctttaa atatttaaaa gacatgggat ttgatactat tgacctctct gttctattag
    27721 aaggttttag ttatgcttat ggtatggatt ggttagaaaa attttttaaa gaaaatcaag
    27781 ataaacttcg cgaattttat taacagtatc aaacaagatg attgtcaatt agccagtcgt
    27841 cttgtttttt atgatgaaat gaaataaaat ctgaacaaat cgcttagaga attccagtca
    27901 atttctagcg ctgtttgaga cgtttcagtg gactatagta aaatgaaata agaataggac
    27961 aaatcgatca ggacagtcaa atcgatttct aagaatgttt tagaaataaa ggtgtactat
    28021 tctagtttca atctattata tttcagattc ggtccactat tccttcccaa aaacattgca
    28081 tattgcgccg aaggaattgc tcatactatc ccaagcacaa aaccctcagt cgtttgaccg
    28141 agggttcctt tttattattc aagaacttga ttagctcaat gcatccaagg cgtcatccat
    28201 tgaaagaact tcgtggaaga cacgttgtgt caattcagtt ttttgttctg gagtgaggta
    28261 tttagtgttt acacagtatc cagagatacg tacgataacg tcttcgcctg acatgatttt
    28321 ttcgtaaaca tcgttcaagt ccataacgtt caagttaacg tgttgtccac cgttttcgaa
    28381 gtaaccatca aggattgtta ccaagttatc aacttgttca tcacgagtct taccaagagc
    28441 gcgaggtgat acttgtgtag tcaatgagat accgtcagct gcataactaa agtcaaggct
    28501 agaaagtgag ttcaagtttt gcaaccaacc acctttagct ttgttagatg ggttagcacc
    28561 tggtgagaag aattcaagtt tagacaagtt cacagaacca tcttcgttga ggtatacacc
    28621 tttgtgaact ggtgagttac cagtttgttt agagtaagca acgttagatg tgattgtcaa
    28681 aagtgatact gtagcttctg cgtctttgta tagtttgtgg ctacgtagac gagttgtgta
    28741 agcttcgatc aaccattctg ccaattcgtt tgaacgtggg tcatcttcac cccagcgtgg
    28801 gtagtcaccg attgtttcgt aatcgtagat gtagccatct tcgtcacgga ttggtttaac
    28861 tgtagcgtat ttgatagctg acaatgtatc aacagtgtta gcaaatccac agataccgaa
    28921 tcccatgttg gcacgttgtt tagttggcaa gaaggccatt tgaacagctt cgtagttgta
    28981 cctatcagtc atgtagtgga tgatgttcaa ggcatctacg taagtgtcag tcaaccagtc
    29041 aagagatttt tcaaagttcg ctttaactga ttcgaattca agaacttcgt cacggattgg
    29101 ttcgatatca aatactttgt agtctttgtg aacatcgtcg taaccaccat tcaaaccagt
    29161 aagaagggct ttaagaacgt ttacacgagc accgaagtac tggatgttgt ggcgttgttc
    29221 ttcattttct ggatcaagtg gagacacaca gcatgagata cagctcattt caccatatcc
    29281 gtctttagcc attgttgtta caccttcgta ttggatagaa gagtgtttgt ggctcatgtg
    29341 catacagtag cgacggaagt tgtatggcaa tttgtcagtc caaagaactg tcaagtttgg
    29401 ttctggtgag ttaccgatgt tgtcaagagt gttcaagaaa cggtagtcca tcttagtaac
    29461 acggtgacga ccgtcgttac ccataccagc catagaagtt gtgataaagg ttgggtcacc
    29521 tgagtacaat tggtcataag cttttgtacg agcaaattta actgtacgaa gtttcataac
    29581 gaaatcatca acgaattctt ggatttctga ttcagtaaat gtaccacgag caaggtcacg
    29641 ttctgcaaag atgtccaata cgattggtac acgacctaga gatgtagcag caccgttaat
    29701 cacacggcag acagccatga aagcaatgtt aacccattgg attgcttctt tcacgttcat
    29761 cgctggtttg cgaacatcaa ccccgtaaag gtcacccagg cgaacaactt gttgcaatgc
    29821 ttggtattga aggtttactt cttcacgaag acggattgtt tcttcatcga tttctttgat
    29881 tgcattccag tcgtttactt tttcttgcat caagtagtct gcaccgtaaa gagcaagacg
    29941 tgcgtaaaca ccgatgatac gtccgcgtga gtatgcatct ggaagaccag ttacagtgtg
    30001 tgcatgacga gcgcgacgaa tatttgaagt gtaggcacgg aaaataccgt cgttaactgt
    30061 tgttacatat ttagtgaaga tttcgtgaac agctgggtct ggttcgtatc cattttcttt
    30121 taaagtagtt tcagccatac ggataccacc ttttggcatg aagttcaatt tgaagagttc
    30181 atcattttgg ataccaaaga taacttcatt ttctttgtcg ataaatccag cagggatatc
    30241 agcgatagat gttggacgag tgtccattgg gaaacgagtt tcttcgtagt gtgctttagt
    30301 ttcttctaca attttcttga tgtgaagtga acgctctgtt ggtcctgcaa ggaagctttc
    30361 gtctccatca taaggtgtgt agttagcttg tacaaagcgt gatacacttg ctttttcttt
    30421 ccaatctacg cctttgaagc cttcccaagc tttgtcaaaa atatcttgtg cttcaacaac
    30481 tgtcttaaca accatattaa tgtcctcttt tttctagtaa cagtcatctg ttacattcat
    30541 aagacaagta taccataaag taaccgattt caacaagtgc aaaatcccta tttttacact
    30601 ttcttttcta aaacagtcta tattttattt caaactgtat tatatttttg aaaaaaataa
    30661 agtccttttt tctttttttc agaaaaaagg gtataataaa agaaaataag cagtaacact
    30721 caatggaaat cgaaaagcaa actaggaagc tagccgcaga ttgctcaaaa cactgttttg
    30781 aggttgcaga tagagctgac gtggtttgaa gagattttcg aagagtataa aaaggtgcta
    30841 ggcatgttga tttttccttt gttaaatgat ttgtcaagaa aaatcatcca tattgacatg
    30901 gatgcctttt ttgctgcggt ggaaatcaag gataatccta aactcagagg aaaacctgtc
    30961 attattggaa gcgaccctcg gcaaacaggt ggacggggag tcgtttctac ctgtagctat
    31021 gaggctcgag cttttggtgt ccattctgcc atgagttcca aggaagctta tgaacgttgt
    31081 ccccaggccg tctttatctc aggaaattat gagaaataca aagctgtggg actccagatt
    31141 cgagctattt ttaagcgcta tacagatttg attgaaccca tgagcattga cgaagcctat
    31201 ttggatgtga cagaaaataa actcggtatc aagtcagcgg tcaaaattgc tcgcctcatt
    31261 caaaaagata tctggcaaga actccatcta actgcttctg ccggtatttc ctacaacaag
    31321 ttcttagcta aaatggcgag tgattatcaa aaacctcatg gtttgacagt gattctacct
    31381 gaacaggctg agaattttct caaacaaatg gatatttcca aatttcatgg agtaggaaaa
    31441 aagacagtag aacgtcttca tcaaatgggc gtttttactg gtgctgattt acttgaagtt
    31501 cctgaggtga ccctaataga ccgttttggt agactaggct atgatctgta tcgaaaggct
    31561 cgtggcattc acaactctcc agtcaaatcc aatcgcatcc gtaaatcaat cggcaaggag
    31621 aaaacctacg ggaagattct ccgtgctgag gaagatatca aaaaagagct gactcttcta
    31681 tcagaaaaag tcgctctcaa tctacatcaa caagaaaaag ctggaaaaat tgtcattttg
    31741 aaaatccgct acgaggactt ttcaactctt accaaacgaa aaagtcttgc tcaaaaaaca
    31801 caagatgcta gtcagataag ccaaatagcc ctgcaactct atgaagaatt aagcgagaaa
    31861 gaaagaggtg tccgcctatt ggggattacc ctgactggat tttaaagctc aatgaaaatc
    31921 aaagagcaaa ctaggaagct agccgcaggc tgctcaaaac actgttttga ggttgcagat
    31981 aaagctgacg cggtttgaag agattttcta agagtataaa accttgaaga gttgcccctt
    32041 caaggttttt cttatacaaa taaacggaca aaactgtaaa gtagcaaaac actaccaagt
    32101 acgatacggt atttaccaaa aagggtgaag tcgtgttttt tcacatagct ggtcaagaag
    32161 cgaatagcca ccatgctgac cgcaaaagct actcccatcg cgaccaagag caaaaacaat
    32221 tgcccaaagc tcaagagttc tccggctttc acaaatttga aaatctttaa ggcactagct
    32281 ccaaacataa cgggaatccc aagatagaag gtaaattctg tcacaactga acgactggtt
    32341 ccatttaaca aaccaccgac aatcgttgca cctgaacggc tagtccctgg taaaagagca
    32401 agaacttgga agagtccgat atagaaagcg gtcgtataag gaagcttgtc caactctgtt
    32461 acacttggct cgatagcacg cgctttattg cgcttttcca aatagatgaa ggcaaccccg
    32521 tagataatca acatgagagc aactgaaacc atgttatgga agtgggtatc aaaccaatca
    32581 tcaaatttaa agacaccaag taaaggtaaa gtagcaatca agaccttcaa ccatagtctc
    32641 caagtcttac gaacttcctg tttgtcctta gtcggtttaa aaggattgag cttgttaaaa
    32701 taaatcacca taactgctaa aatagcacca agctgaatca cgacattaaa catggacata
    32761 aaggcttcat tttgattttg gtattggatg aattcctctg ctaaaatcaa gtgacctgta
    32821 ctggaaatcg gcaaccattc cgtaattcct tcaacaatcc cgaagaagat agattttaaa
    32881 atttcaataa gatacataga ttactcccta tattataatt agcgcagtta gctactgcca
    32941 aagcccaagt ggtatacttg gaataagcca ctgtggatta gttcatttcc tccaatcgct
    33001 tgacgatttc cgaaaggatc taaccacagc ttttgtttca attggtaatg agtttgataa
    33061 cgcatagacg ttttatctcg tctaaggtaa caaggcaaaa agttcgtgga taaccaagta
    33121 gacttgaaat actatatctg gaggtactcc catgctttat gtgggcattg atatcgctaa
    33181 aaataaacac gatgttacag ccttgaat
//
LOCUS       DBERXF010000022        32794 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.22, whole genome shotgun sequence.
ACCESSION   DBERXF010000022 DBERXF010000000
VERSION     DBERXF010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32794
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.22"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            485..1846
                     /gene="trpE"
                     /locus_tag="ACL8JK_001164"
     CDS             485..1846
                     /gene="trpE"
                     /locus_tag="ACL8JK_001164"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HGS1786057.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESISRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            1843..2409
                     /locus_tag="ACL8JK_001165"
     CDS             1843..2409
                     /locus_tag="ACL8JK_001165"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HGS1786058.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEEGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            2420..3424
                     /gene="trpD"
                     /locus_tag="ACL8JK_001166"
     CDS             2420..3424
                     /gene="trpD"
                     /locus_tag="ACL8JK_001166"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HGS1786059.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            3421..4188
                     /gene="trpC"
                     /locus_tag="ACL8JK_001167"
     CDS             3421..4188
                     /gene="trpC"
                     /locus_tag="ACL8JK_001167"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HGS1786060.1"
                     /translation="MSQEFLARILEQKVREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINHDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            4175..4774
                     /locus_tag="ACL8JK_001168"
     CDS             4175..4774
                     /locus_tag="ACL8JK_001168"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HGS1786061.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRAELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGEGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            4752..5975
                     /gene="trpB"
                     /locus_tag="ACL8JK_001169"
     CDS             4752..5975
                     /gene="trpB"
                     /locus_tag="ACL8JK_001169"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HGS1786062.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGSPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            5968..6744
                     /gene="trpA"
                     /locus_tag="ACL8JK_001170"
     CDS             5968..6744
                     /gene="trpA"
                     /locus_tag="ACL8JK_001170"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HGS1786063.1"
                     /translation="MPKTLTEKLNAIKATGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFIYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(6716..6817)
                     /locus_tag="ACL8JK_001171"
                     /pseudo
     CDS             complement(6716..6817)
                     /locus_tag="ACL8JK_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            7046..7777
                     /locus_tag="ACL8JK_001172"
     CDS             7046..7777
                     /locus_tag="ACL8JK_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786064.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDENSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            7792..8943
                     /locus_tag="ACL8JK_001173"
     CDS             7792..8943
                     /locus_tag="ACL8JK_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1786065.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKKEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(8995..9654)
                     /locus_tag="ACL8JK_001174"
     CDS             complement(8995..9654)
                     /locus_tag="ACL8JK_001174"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGS1786066.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLL
                     V"
     gene            9724..10170
                     /locus_tag="ACL8JK_001175"
     CDS             9724..10170
                     /locus_tag="ACL8JK_001175"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1786067.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGSRIPFLLTLQ
                     ALEEVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            complement(10398..11576)
                     /locus_tag="ACL8JK_001176"
     CDS             complement(10398..11576)
                     /locus_tag="ACL8JK_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGS1786068.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NELIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            11856..13118
                     /locus_tag="ACL8JK_001177"
     CDS             11856..13118
                     /locus_tag="ACL8JK_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS1786069.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFI
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            13121..14017
                     /locus_tag="ACL8JK_001178"
     CDS             13121..14017
                     /locus_tag="ACL8JK_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HGS1786070.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNQEIIKAVQSAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            14032..14349
                     /locus_tag="ACL8JK_001179"
     CDS             14032..14349
                     /locus_tag="ACL8JK_001179"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1786071.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            14366..14683
                     /locus_tag="ACL8JK_001180"
     CDS             14366..14683
                     /locus_tag="ACL8JK_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS1786072.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            14693..16048
                     /locus_tag="ACL8JK_001181"
     CDS             14693..16048
                     /locus_tag="ACL8JK_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS1786073.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGCFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            16372..17847
                     /locus_tag="ACL8JK_001182"
     CDS             16372..17847
                     /locus_tag="ACL8JK_001182"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HGS1786074.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            17844..18692
                     /locus_tag="ACL8JK_001183"
     CDS             17844..18692
                     /locus_tag="ACL8JK_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HGS1786075.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVSNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            18707..19477
                     /locus_tag="ACL8JK_001184"
     CDS             18707..19477
                     /locus_tag="ACL8JK_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGS1786076.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(19755..20000)
                     /locus_tag="ACL8JK_001185"
     CDS             complement(19755..20000)
                     /locus_tag="ACL8JK_001185"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGS1786077.1"
                     /translation="MAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDISNHHDSESFF
                     ANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            20279..20518
                     /locus_tag="ACL8JK_001186"
     CDS             20279..20518
                     /locus_tag="ACL8JK_001186"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1786078.1"
                     /translation="MNERYQCLKTKEYQALLSSKGRQIFAKRKIDMKSVFGQIKVCLG
                     YKRCHLRGKRQVRIDMGFILMANNLLKYNKRKRQN"
     gene            complement(20613..20816)
                     /locus_tag="ACL8JK_001187"
     CDS             complement(20613..20816)
                     /locus_tag="ACL8JK_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGS1786079.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(20847..21455)
                     /locus_tag="ACL8JK_001188"
     CDS             complement(20847..21455)
                     /locus_tag="ACL8JK_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS1786080.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(21494..21664)
                     /locus_tag="ACL8JK_001189"
     CDS             complement(21494..21664)
                     /locus_tag="ACL8JK_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGS1786081.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(21676..22242)
                     /gene="amaP"
                     /locus_tag="ACL8JK_001190"
     CDS             complement(21676..22242)
                     /gene="amaP"
                     /locus_tag="ACL8JK_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGS1786082.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(22326..22550)
                     /locus_tag="ACL8JK_001191"
     CDS             complement(22326..22550)
                     /locus_tag="ACL8JK_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000269692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGS1786083.1"
                     /translation="MIAGGLIGLLAGKITKKSSSMGIIANVFAGLVGASAGQSLLGSW
                     GSSIAGMALLPSIVGAAIVITVVSFFTGRK"
     gene            22934..24424
                     /gene="mgaSpn"
                     /locus_tag="ACL8JK_001192"
                     /gene_synonym="mgrA"
     CDS             22934..24424
                     /gene="mgaSpn"
                     /locus_tag="ACL8JK_001192"
                     /gene_synonym="mgrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator
                     MgaSpn"
                     /protein_id="HGS1786084.1"
                     /translation="MRDLLSKKSHRQLELLELLELLFEHKRWFHRSELAELLNCTERA
                     VKDDLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNE
                     GCQAESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQY
                     FSEKYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGH
                     FMEIDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFID
                     ESLFMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELF
                     TEFILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHT
                     KHLVINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLE
                     DSSYDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            24786..25781
                     /locus_tag="ACL8JK_001193"
     CDS             24786..25781
                     /locus_tag="ACL8JK_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1786085.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            25908..27212
                     /locus_tag="ACL8JK_001194"
     CDS             25908..27212
                     /locus_tag="ACL8JK_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HGS1786086.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGGGYEDKVNAAITTNSLPDVITLDG
                     PNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYNKK
                     MFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYMPL
                     IWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYPML
                     LSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASEFV
                     KFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVAYP
                     QVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            27308..28210
                     /locus_tag="ACL8JK_001195"
     CDS             27308..28210
                     /locus_tag="ACL8JK_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1786087.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMISLVQRRVLKEDD"
     gene            28212..29057
                     /locus_tag="ACL8JK_001196"
     CDS             28212..29057
                     /locus_tag="ACL8JK_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1786088.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            29067..30386
                     /locus_tag="ACL8JK_001197"
     CDS             29067..30386
                     /locus_tag="ACL8JK_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGS1786089.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKIEQNPVATGADLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNVQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(30596..30668)
                     /locus_tag="ACL8JK_001198"
     tRNA            complement(30596..30668)
                     /locus_tag="ACL8JK_001198"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30633..30635),aa:Lys,seq:ctt)
     gene            complement(30933..32204)
                     /locus_tag="ACL8JK_001199"
     CDS             complement(30933..32204)
                     /locus_tag="ACL8JK_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGS1786090.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            32474..32713
                     /locus_tag="ACL8JK_001200"
     CDS             32474..32713
                     /locus_tag="ACL8JK_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786091.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
BASE COUNT        10261 a         5334 c         6857 g        10342 t
ORIGIN      
        1 actgttttga ggttgcagat agaactgacg aagtcagtaa ccatacctac gataaggcga
       61 cgttgacgcg gtttgaagag attttcgaag agtataaagg tgtaccgaga tgaacatctc
      121 ttcatcaatg tctctggtcg tggaggcaag gacctagctg cgattgcaga ttactagaag
      181 ctaaaaaata atagatggaa aaattacagt tctttctctc acagagagct tgtggttgct
      241 gaaaacaagc agagaaagct gtaaagttgg gttcatctga aacgagagaa gaaaacatca
      301 ttctcaaggg agtgcccttt atcgcacagc ctgttacagg agatatctga gacaggaatg
      361 agagatagga gaaatcctat aattgaggtg gcaccgcgaa tttcgtcctc acgcaagtta
      421 ttttgcgtgg ggatttttca tacagtcacc acggactaga agtagaactg aaagggaaat
      481 tacaatggaa cgaatcattc atggagatgt cttatcacca atcttggctt atatgcgctt
      541 aaaggggcaa cataaggtta ttttagagag tatttcgaga gacaaggaaa cagctcgttt
      601 ttctatccta gcctataatc cagtttttga gattaagttt gaaaatgggg ttctctatca
      661 aaatggtcaa gtgattgatc gggatccctt ggatttcctt tatgaagtga ttcataagag
      721 tcagcaccac tcagagctac cttttggtgg tggagccatt ggttttgtgg gttacgatat
      781 gatttcgctt tatgaagaaa ttggtcaaat ccctgaggat acaattggga cgccagacat
      841 gcatttcttt gtctatgaga gctatatggt ctttgaccac aagaaggaga agatacatgt
      901 catagaggat gcactttata gtgagcgcag tcaagaggcc ttggaaaaat ccttgaacca
      961 agtgcttgag gaattacgca ttcctgctcc aaatgaattt gaagatttgg atctatctcc
     1021 gttagacttc aaaccgcata tcgctccaca taagtttgag ggaatggtag aaacagctcg
     1081 tgacttgatt cgtaacggag atatgttcca atgtgtactc agccagcgtt tttcagcaga
     1141 agttactgga aatccatttg acttctacag aaatctccgc gtgactaatc cttctaatta
     1201 cctttatttc tatgattttg gggattatca aatcatcgga gctagtccag aaagtttagt
     1261 ttctgtcaaa aatggcatcg tgacaaccaa tccgattgca gggacgcgac caagaggggc
     1321 tacggatgaa gaagacaaga ccttggcgac tgacctcctc tctgatgaga aggaaacagc
     1381 agaacatcga atgttggtag acttggggcg taacgatatt ggccgcatct ctgaaacggc
     1441 cagtgtccaa gttactaagt atatgaaggt ggagctcttc cgctacgtca tgcatttgac
     1501 cagcgtggtc aaggggcgtt tgcttccaga actcacggcc atggatgcct tgaaagctac
     1561 acttcctgct ggaaccgttt ctggagcacc aaagattcgg gcgatgagac gcatctatga
     1621 actggaaacg gaaaaacggg gcgtatatgc aggagcaatc ggctacttgt ctgcgacggg
     1681 tgatatggat ttggccattg ccatccgaac catgattctc aaaaatcaaa gagcctatgt
     1741 gcaggctggg gcagggattg tctacgactc tatcgcccaa aacgaatacc aagaaaccat
     1801 taacaaagca aaatctatga ctagaattgg agaactaaga ccatgatttt attgattgac
     1861 aactatgatt cttttaccta taacttggcc caatacattg ggaattttgc agaagttcag
     1921 gttctgagaa atgatgattc caagctgtat gaagaagctg aaaaagcaga tggtctggtc
     1981 ttttctcctg gtcctggttg gccagttgat gctggaaaga tggaagacat gattcgtgat
     2041 tttgcaggca agaagccgat tcttgggatt tgtttgggcc accaagccat tgcagaagtc
     2101 tttggtggta agctaggttt ggctccaaaa gtcatgcatg ggaaacagag caatatcaac
     2161 tttgaagcgc catctgtttt gtatcaaggt attgaggaag gacgtgcggt catgcgttat
     2221 cacagtattt tgattgagga aatgccagaa gactttgaag tgacagctcg ttcgactgat
     2281 gaccaagcca tcatggggat tcaacataaa aacctaccga tttatggctt ccagtaccat
     2341 ccagagagca ttggaacgcc agacggcttg tcttctattc ggaattttat cgagaaggtt
     2401 gtaaagtgag gaaactagga tgaaagagat tattgaaaaa ctagcaaaat ttgaaaattt
     2461 atcaggtgtg gaaatgacgg atgtcattga gcgtatcgta actgggcgtg taactgaagc
     2521 gcagattgct tctctcctct tagctcttaa gatgaagggg gaaacacctg aagaacgcac
     2581 agccattgcc caagtcatga gaggacatgc ccagcatatt ccaactgaga ttcatgatgc
     2641 catggacaac tgtggtacag gtggggacaa gtctttcagt tttaatattt ccacaactgc
     2701 agcctttgtc ttggctggtg gcggtattca catggccaag catggtaacc gctcgatttc
     2761 ttctaaatct ggttccgcag atgtcctcga agccttggga atcaatcttg acctcaaacc
     2821 agctgaacta ggtaaggtct ttgataaaac tggaatcgtc tttctcttcg ctaaaaatat
     2881 gcacccagct atgaaataca tcatgccagc tcgtttggaa ttgggaattc caacgattat
     2941 gaacttgact ggtccactga ttcatccaat ggctttagaa acacagcttc ttggaattag
     3001 tcgtccagaa ctcctagaaa gtacagctca ggttttgaaa aatatgggtc gcaaacgtgc
     3061 catcgtggtt gctggaccag aagggttgga tgaagctggc ttgaacggaa caaccaagat
     3121 tgcacttctt gaaaatggcg aaatcagctt gtcaagcttt actccagagg atttgggaat
     3181 ggaaggctat gctatggaag atattcgtgg tgggaatgct caggaaaatg cagaaatttt
     3241 gcttagcgtt ctgaaaaacg aagcaagtcc attcttggaa acgacagtct tgaatgctgg
     3301 tcttggtttc tatgctaatg gtaagattga tagcatcaag gaaggagttg ccttggcccg
     3361 tcaagtgatt gctagaggca aggcccttga aaaactcaga ctgttacagg agtaccaaaa
     3421 atgagtcagg aatttttagc acgaatctta gagcagaagg tgcgtgaggt ggagcagatg
     3481 aagctggagc aaatccagcc tctgcgccag acctatcgct tggcagagtt tttgaagaat
     3541 catcaggacc gcttgcaggt aatcgctgag gtcaagaaag ctagccctag tttgggagat
     3601 atcaatcacg atgtggatat tgtgcaacag gcccagactt atgaagaaaa cggagcagtg
     3661 atgatttcgg tgttgacaga tgaggttttc tttaaagggc atttggatta tctacgggaa
     3721 atttccagtc aggtagagat tccgacgctc aacaaagact ttatcatcga tgaaaagcaa
     3781 atcatccgcg ctcgcaatgc aggtgcgaca gttatcttgc tcattgtggc agccttgtcc
     3841 gaagaacgcc tcaaggaact gtatgactac gcgacagagc ttggtctgga agtcttagtg
     3901 gagactcaca atctagctga actagaggta gcccacagac ttggtgctga gattatcggg
     3961 gtcaacaacc gcaacttgac tacctttgag gtcgacttgc agaccagtgt agatttagcc
     4021 ccttactttg aggaaggtcg ctattacatt tctgaatctg ccattttcac agggcaggat
     4081 gcggaacgac tagccccata ctttaacgga attttggtag ggacagctct tatgcaggca
     4141 gaaaatgtgg cccagagaat caaggagttg cagattgaca aaggttaaaa tttgtggact
     4201 atcgaccaaa gaagcggtgg aaacagccgt ttcagcagga gccgactata tcggttttgt
     4261 ctttgcacct agtaaaagac aggtgacttt agaagaggca gctgagttgg caaagcttat
     4321 tcctgcagat gtcaaaaagg ttggtgtatt tgtttcacca agtcgggcag aactgctgga
     4381 agcgattgac aaagttggct tggacttggt tcaagttcac ggtcaggtgg cagatgattt
     4441 atttgagaat ttgccttgtg ctagcattca ggctgtgcag gtagatggag agggtcatgt
     4501 gcccaattct caggcagact atctactctt tgatgcccct gtggctggga gtggccagcc
     4561 ctttgattgg ggtcaactgg atacgactgg actagcacag cccttcttta tcgcaggtgg
     4621 ccttaatgaa gataatgtag taaaagcaat tcaacacttt actccctatg cagtagatgt
     4681 atcaagcgga gtggagacag atggacaaaa agatcatgaa aagattagaa gatttataga
     4741 gagggtaaag aatggcatat caagaaccaa ataaagatgg attttacgga aaatttggcg
     4801 gacgttttgt cccagaaaca ttgatgacag cagttttgga gttggagaag gcctaccgtg
     4861 aaagtcaggc agacccaagt ttccaagagg aattaaacca gcttttgcgc cagtatgtgg
     4921 gacgtgaaac tcccctttac tacgcaaaaa acttgaccca gcatatcggc ggagccaaga
     4981 tttatctcaa acgggaagac cttaaccata caggagccca caagattaac aatgccttag
     5041 gacaagtttg gcttgccaaa cgcatgggta aaaagaaaat tatcgcagaa actggtgctg
     5101 gtcagcacgg tgtggcaact gcaactgctg cggccctctt taacatggaa tgtaccatct
     5161 acatgggtga ggaagatgtc aaacgccaag ccctcaatgt cttccgtatg gagcttttgg
     5221 gagctaaggt cgaggccgtg acagatggtt cgcgcgtgct caaggatgcg gtcaatgcag
     5281 cccttcgttc atgggtggct aatatcgacg atacccacta tatccttggt tctgccttgg
     5341 ggcctcatcc atttccagaa atcgttcgtg acttccaaag tgtcatcggt cgagaggcta
     5401 aacaacagta ccgtgacttg acaggtcgag atctgccaga tgccctagta gcctgtgttg
     5461 gtggtgggtc gaatgctatc gggctcttcc atccctttgt agaagatgag tcagtagcta
     5521 tgtatggaac tgaagcagca gggcttggtg tggatacaga gcaccacgct gctaccttga
     5581 ccaagggtag tccgggtgtt cttcacggtt ctctcatgga tgtgctccaa gatgcccatg
     5641 gtcaaattct tgaagccttc tctatctcag caggtttgga ctatcctggt atcggtccag
     5701 agcattctca ctaccacgat atcaaacgtg ccagctatgt ccctgtgaca gacgaagaag
     5761 ctttggaagg atttcaactc ttgtctcgtg tggaagggat tatcccagcc ttggaatcta
     5821 gccatgctat cgcttttgcg gtgaaattgg ccaaagaact tggaccagaa aagtctatga
     5881 ttgtatgcct atcaggtcgt ggggacaagg atgtggttca agtcaaagac cgcttggaag
     5941 cagatgcagc aaagaaggga gaagctcatg cctaagacac taacagaaaa attgaatgct
     6001 ataaaagcaa ctggaaaagg aatttttgtt ccctatatca tggctggtga ccacgagaaa
     6061 ggtttggacg gtcttgctga aacaattcac tttttagaag atttgggtgt ctctgcaatt
     6121 gaagtgggta ttcccttttc agaccctgtt gcagatggac ctgttatcga agaagctggc
     6181 ttgcgcagtt tagcccacgg gacctctacc caggctttag ttgaaacctt gaaaaccatt
     6241 gaaacagaga ttccactggt catcatgacc tacttcaacc ccctctttca gtacggtgtg
     6301 gagaactttg tcaaagatct ggctgataca gctgtgaagg gcttgattat cccagacctg
     6361 cctcatgaac atgccaactt tgtagaacca tttttggcag atacagatat cgccttgatt
     6421 cctttagtaa gcttgaccac aggaattgag cgtcagaaag agttgattga aggggcggag
     6481 ggattcatct atgccgttgc catcaatgga gtgacaggga aatcaggcaa ttaccgtgca
     6541 gatttggaca agcacttggc gcaacttcat caagtggccg acatcccagt cttgacaggt
     6601 tttggtgtat ctagtcaagc cgatctggaa cgcttcaatg cggtgtcaga tggtgttatc
     6661 gtcggttcaa aaatagtaaa agctctccac caaggagagc cgattcagga ttttatcaga
     6721 caagcagtag cttaccaaaa ataatcaaac aagtagcaag taagaggaaa ggcacgaaag
     6781 gaagtctttc ctttttcttt tgcaggagaa aggtcagttt tatagtgaat tgaatctgga
     6841 atattacact acggttccta aaatattttc agaaagcgat ttgaatttcc caataaattt
     6901 gttcagtttt taattgattt tactatagaa gatataattt tctaaattac tctgacacag
     6961 aactttaaga aaaagataat tattgtagta atttctttaa gaaaatggta taattcatta
     7021 aaaagtattt ggaggaggaa gaattatgtt gaatcaggat ctctttgatt cgcttgaggc
     7081 acaaaaaatt gtagatactt tgatgaaagg gcaaaaagat tatgtagatg aacgtctaga
     7141 aaaaagagag acaatgatag tgtcgaatgg ttatgcatgg acgcgaccta atcatattga
     7201 tactgcattt gcatcagcag atttgtttga gtataaatta caattagcag gacagacttg
     7261 gggatattta gaatttgaaa caaatacaga aaaatatggg aaagtattgt taattataaa
     7321 gggtaagaag cgacttacga accaatttcc tttggtacaa aaaaataaga gtggctactt
     7381 atttgaatat gctcagatga atacacttta tcttaatcaa cattcttcct acaaaaatga
     7441 tgaaaatagt cattcctttc caattcagat ggagttagtt tctgatgaaa tgattcaaga
     7501 aattgaacaa gctactaaaa attcgaatat cgaaaaattt atgattttaa cttatgaggc
     7561 ggactcagaa aacaatatta tatctgtaga tgttgttatg cctgatgcac gaactggtca
     7621 gttacacttg attcaagatt tgtctgagta tattcaatca agttcgtacc atttcgaaga
     7681 agctaaatat caagatattc ctaatttttc agaattatcg gaaacagaag attttgaaat
     7741 tattccaaga atagaaaaac aagaaggtca aaagtagtaa ggagtatgta aatgtttaat
     7801 ggtcgggtat tgaaagaatt acggctgtta aatggtttaa gtagagcaga attagctcag
     7861 agaattaatt taacggaaca agccatttgg cagtttgagt ccaacgaaac gaaacctaaa
     7921 ttatcaacca aaatgcattt ggccaaccaa tttcatgttg atttaactta ttttgaacag
     7981 gaagaagaga gcattcgatt tgattcttct gtaattgcct ttagaaatgc agacctagca
     8041 acacggaaaa caatagatat tcaaactatg tatttacata aggtagatag tttgattgat
     8101 tattttgaaa gttttgtaat tatacctaat attataattc atgacctaag taatgtagtg
     8161 agtgaatctt atcataaggg agaatccatt gaggaattgg ctctttatgc cagggaaaaa
     8221 ttaggtattt caaaagataa tcatgatttg ctttataaat tagaacgttc aggcatctat
     8281 atcgtggaac gattaattaa tggccaagct gatgcttata gcgcatggtc aaaattggga
     8341 agaccttata ttgtgttagg aacgaataaa tcatctgtac gtcgaaattt tgacttagct
     8401 catgagctag gacatattct tttacataaa tataaagata tgaatgaaga tggcgatcgt
     8461 ttggagcaag aagcaaatta ttttgcatca tgttttttat tgccaaaaaa agagttttta
     8521 gtcaaatttg aagagagggt tggcaagcgt gtcagcaatc ctgatagtta tattttattg
     8581 aagtcggatt tgaatgtttc gatacaggct ttagagtatc gagcttttaa gttaggatta
     8641 ttgactccaa agcaacattc ttacttttat cgtcaaattg cgcaaaaagg ttacaaaatg
     8701 attgaacctt tggatgatca aatttttgtt aaaaaaccaa gcaaagtaaa gagtattctg
     8761 gacgtcgttt tgagtaatca tctagtcagt ctagcgacta taatgtctaa acaaagtatt
     8821 cgtttacagt ttataagcga aatattttca gtcgaaatga aattttttga tcagtatcaa
     8881 gaagatagaa gaacagatcg atttgataac atcatccctt tgtacaaaag aaataattta
     8941 taatttaact gtgaaataat ttcatgaagg acatatggca gaaattggat tttatcagac
     9001 aagcagtagc ttaccaaaaa taatcacaca agtagcaagt aagaggaaag gtacgaaagg
     9061 aagtctttcc tttttctttt gcaggagaaa ggctaggata cccgtcgcag aagcaaactg
     9121 aatcaagatc agtaactccg ttatgctaaa gacgagagca caagaagcta aaaagaggaa
     9181 atcccctgcg cccatgcgga tatcgataaa atgagccaaa attccaagag caaggaagga
     9241 gaccatgacc agattccagc cagaggaagc tattaggatt aggtggaaag tcatccagac
     9301 cagtaaggga tattcctgat ggcgaaagtc atagatgctc aaggtcaaac cagcggtgat
     9361 taggacgact tgccccaagg aaagcaattc ccaagagtaa agcagaaaga ggagtcctaa
     9421 gcctagttca aagagggcat accagacagg atagcggacc ttgcagtagc gacagcgaaa
     9481 gcgattgaag acctgtgaga gaatcggaat caaatctaag ggacgcaagg gagtctgaca
     9541 ggaatcgcag tgactggctg aactgataat ggattgctct ggaaaacggt caatgaccaa
     9601 accaagaaag gaagcgagaa tgctcccgac gagaaaaaaa taaaaatcaa tcatacttat
     9661 ctattcgtaa aaaatgggag aaatagtata atggagaaac atagataaga tggtgaggaa
     9721 aagatgacaa ttcgttttga agaaaaggtg agtatagaaa acgctcaatt tgtatgccaa
     9781 tggtccaact ccctaggcaa atcctttcaa gaacaatgga tgggatcaag gattcctttt
     9841 ctactgaccc ttcaagcctt ggaagaagtc ttttcaatct ttgatgaaca agagtttgtg
     9901 ggacttatcc agaaaatcag gctagaagac agcaatcttc atatcgggag attttttatc
     9961 aacccccaga aacaggggca aggcttaggt agccaggctt taaggaaatt tgttagtttg
    10021 gcctttgaaa atgaagatat agatagtatt tctctaaatg tcttcgaggc aaatcaaaga
    10081 gctcagaatc tttaccaaaa agaaggattt gaaatcgttc aaatggttga agcacctgta
    10141 cgaaaatata gtagattgaa actagaatag tacacctcta cttctaaaac attgttagaa
    10201 atcgatttga ctgtcccgat cgattcgtcc tgttattatt tcatttcact atacattatg
    10261 aaaaagggga gataggagta taattccaaa tataaagaaa gcgaacaaaa cagaattctg
    10321 attttcagaa aacaggttta ttcgcttttt atgatatact ccctcttttt agcctattta
    10381 ttaaatgtaa tagaaaatta agaatgtaga attgtatgat acaaacaaag tgcaatagct
    10441 gagtgtgcgg ctgtaaaatc attgtaaggt tcaataatga cttcaggtag gcgattatag
    10501 agcagtttgg gtttgtagtt catttcacta tatagttttt ggatgatgtg ttgatttgtt
    10561 agtaaaggac tatgtaggta gattttttga gagtcaatca tcatactgat atttaaaatg
    10621 gtttgactaa gatagagtaa ggcttgatgg ataagtgtga ttattccagt gtcacctaat
    10681 tgataagcgg ttaaaataac ttggatatca atatcatcgg catttttgac taaactagga
    10741 agtagagaat agggagattg atgatataga atttttgatt ttttgattaa ccaagattct
    10801 ccagcaaaag tttgtaagca tcccttgcgc ccgcagctac attcttctcc ctcagatgaa
    10861 acaactgtat gccctatttc tccaatcatt agatttcctt tcccataaat gtttccgtcg
    10921 tagatataag aacagtgcat acctctagca aaatgaaaat aagcaaaatt agggtcattc
    10981 tgttggcgac taaataggcg tttacctata gccatacagt taacattgtt agagaaaaac
    11041 aaaggcttat caaagtggga ttgaatcatt tctaagtcga tatgttgcca taaaggattg
    11101 tttgttgtta ttttataatc atctaaatag cgaccaggta gcgcgattcc aattgcttct
    11161 atttcataat cagagcagtt atttaagaat tgctttagtg tctggttaat gagttgattt
    11221 cccttttctt ggattaactg tttagtaaca atttctttct cttcctttaa gatatttcct
    11281 agattatctc ctaaagcaaa agtgaaatgt ttttcagata gttcacaacc aatgtagtaa
    11341 aatcgtttag cttgaatgtc tagcaggatt ttttttctcc ctacgcttgt atcgtgttcg
    11401 tcttcaccaa gttctaagag aatgttttct ttaatcagct catttgtgat actgctagtt
    11461 gttgcaggtg ttattcctgt tttagtagcg atttcaattc gtgaaatggg acctaatgtg
    11521 taaactgttt ccagtatttt agctcgtagt tgtaattgtt tcttagataa ggtcatatta
    11581 gttttcttcc tagttgtcag attcttaaaa tcctatgatt ttttgctatg gataaatgta
    11641 gatgttaatc tttttaagct tttcattgct tactggtctc tttttattat atattgataa
    11701 taaaaaataa tcaaatattt acacaaatcc ttgacaaggc tttcttatag ttgtaaaata
    11761 taaataacaa aagataatca aataacaact tgacgtcaaa aaataaagat aattgataac
    11821 ttttgataat aaaatatatt taagaggaaa aggttatgga aaaattatta caagaaaagt
    11881 tacttccagt agcggctaga ttgggtaata ataaagcgtt ggtttctatt cgagacggta
    11941 ttactctaac tataccttta ttgttgatag gttcattact aatggttatt gcaagttttc
    12001 ctattccagg atgggaaaaa tatctgggtg atattggtgt tgctgattat ttatggaagg
    12061 gtgttgatag tagttttgga ttacttggtc ttgtagctag ttttggtatc gcttacttta
    12121 tggctagaca atacaaagtt gatggtattc ctgctggtat tgtgtcatta tcatctttta
    12181 ttacagttac gcctttcatt acaggagagg ctggagcagg aatgcctacc gctttcatgg
    12241 catcaaaagg tttatttgtt gctatgattt taggattgat taatggctat atctaccaat
    12301 ggtttataaa tcataatata cagataaaaa tgccggatgg tgttccacca gcagtatcta
    12361 aaagctttag tgccattatt cctggtgcag tgactattgt tggttggttg attgtttatg
    12421 caactttaga taaattaagt ttacctaatc ttcatgaaat tgctcaagta gctttgggag
    12481 gtccacttgg acttttagga aataatgtta ttggtcttct tatcttaatt ttccttaata
    12541 gtagtttttg gtttgtagga ttacacggag gaaatgttgt taatgcagtt atgaaaccgt
    12601 tatggttagc taatctagat gcaaataaag tagcttatca aactggagaa actcttccaa
    12661 atatttttac tagcgtattt atcgataatt ttgtattcat aggtggcggt ggtgcaacca
    12721 taggtttagt tcttgcgtta ggatatttag cacataagaa gaaagctagt aaacaactaa
    12781 aaactttggc acctataact gttatacctg gattatttaa tataaatgaa ccagcaatgt
    12841 ttggcgttcc tattgttttg aacattttgt tactagttcc atttatctta gctccaatgt
    12901 ttaacttact agtagcgtgg ggagcaatgg catcaggttt ggttccgcta acttatacag
    12961 atccaggttg gactatgcca cctgttataa gtggtttact tgctacagga agtatttctg
    13021 gttcattatt acaaattgta ttgattgttt tggatgtctt actttattta ccatttgtaa
    13081 tagctattga aaaacggttt aagttattgg aggattgaga atgaaacgtt taattagtgc
    13141 aaatccatct gagatattac agatgaatgc tgaagaatta aaacaaagta ttttagcaag
    13201 tgaaggtaga gttgttctat ctgaaaatgt agttactcgt gagacatttg ttggggatat
    13261 aactaattct gaaattgcta gagcttttgg agctgatatg attttattga attgtgttga
    13321 tgtttttgag cctaaaattt atgctttgga tagttcaggt gatgatgtta ttcatcgctt
    13381 acaccagctt gttgcttgtc caattggtgt aaatttggaa ccgattgacc catctgcaaa
    13441 gatgctagag gaaacacagg aaattgttgc aggtcgtgtt gctagtgttg aaacattgaa
    13501 gcgaatagag gagttaggtt ttgactttgt ctgtttgact ggaaatcctg gaacaggagt
    13561 tagcaatcaa gagattatca aagcagttca atctgctaaa gagaatttct caggtttgat
    13621 tatagctggt aaaatgcacg gggcaggagt gaatgagcct gtggcagagc tttctgtcgc
    13681 agagcaattg ttggaagcag gtgcggatgt gatacttgtt ccagcagttg gaaccgttcc
    13741 agcctttcat gaccaagagt tgcgtgaagt cgttgatctc gttcatagta agggtggtct
    13801 tgtattgagt gctattggta ctagccaaga aacatctgat acagatacta tcaaggaaat
    13861 tgcacttaga aataaaattt gtggagttga tattcaacat ataggtgacg caggatatgg
    13921 gggactggca acagtcgata atatttatgc attgagcaag gcaattagag gagtgagaca
    13981 tacagtatct cgcttggcta ggtcagtaaa taggtgataa aggagtaagc tatggctaaa
    14041 gtaacaatta tgttagcatg tgcagcaggt atgagtacaa gtctgctagt gacaaagatg
    14101 caaaaggcag cagaagataa ggggttggat gcagaaattt ttgcagttcc agctcctgaa
    14161 gcagaagaaa ttgtagcaac aaaggaagta aatgtgttgc ttttaggccc tcaagttcgc
    14221 tatttactag gggactttca agaaaaacta aaagatagac agattcctgt ggcggttatt
    14281 ccgatgacag attatggaat gatgaatggt tctaaagtct tagatttagc tgaaagttta
    14341 ttagactaag attgaggaga atgctatgaa tgaaagtaat ttagaatctg caatggggct
    14401 aattatgtat ggtggggaag ccaaaagtaa tgctatggag gctattcagg cagcaaaaaa
    14461 aggggatttc tctaaagcca atcgaagatt agctgatgcg aatgctgcct tattacaggc
    14521 gcataaggct caaacagaaa tgttgacaag agaggcacag ggggaagaaa catcaattag
    14581 cctcttgatg gtacacgcgc aagatcattt aatgacgagt ctgacttttg ttgacttggc
    14641 gaaagaagtg gtagaagtat acgaacgatt tgaaaaaaat taggagttta gtatgaatac
    14701 aatgttggat aaaatgcaag aaaaactttc tccaattgca atgaaagttg ggaatcagaa
    14761 gtttttagtt gctttacgtg attcatttgt ggggactatg cctgttatta tgacaggttc
    14821 cattgctttg ttattaaatg cttttctagt ggatttacca caacaatttc acctagaaag
    14881 tattacgaaa acctttcagt ggcttgttga catcaataat ttggtattca agggaagtat
    14941 accaattgtt tccttgttgt tcatctattg cttgggagtg aatatcgcta agatttacaa
    15001 ggttgataca gtttctgctg gtttggtatc acttgcttcg tttgtcattt cgattggaag
    15061 tacagttaca aagagtttcc ctttggcaaa tgtaggagat gtgaaattag atcagatctt
    15121 acaaggaatt gataatctag catttgatgg taaaaatctg atggtaacta ttgggaatgt
    15181 gattccagga aaccatatta atgccagagg ctactttaca gccatgatga ttggattttt
    15241 agcctctatt attttctgta aagtaatgaa aaagaactgg gtaatcaagt taccagattc
    15301 agttccccct gcgattgcta agccgttcac ttctatcatt ccaggattta tggcgatgta
    15361 tatagtagcc atcttgactt atgttttcca tttacttagc aatgacttat tgattgattg
    15421 ggtttacaag gtgttacaaa cgccattact aggtttgtct caaagtttct ttgcagttat
    15481 tctgatgatc tttttaaata agttattctg gttttttggt ctccatggag gaaatgtatt
    15541 ggctcccatc atggaagggc tgtttggagt tgctatgtta gcgaatctgg atgctttcca
    15601 aaaaggtgaa ccgattcctt atatatggac aagtgggtct tttggggcgt ttgtctggtt
    15661 tggaggatta ggattggtac ttgctatttt aattttttca agaaacagtc attatcgaaa
    15721 agttgctaaa cttggtctag caccagttct gtttaatatt ggtgagccgg taaattatgg
    15781 tttaccagtt gtcttgaatc ctttgctatt tataccattt gtacttagcc cggttttcat
    15841 ggcaacggta gcttactggg caacaagctg gggtcttgtt tcacctgtta cacaaaatgt
    15901 tacttgggta atgcctccaa ttttatatgg ttgcttctct acagcatttg attggcgtgc
    15961 catcatctta tcagttgttt gtttgattat tagtgtcttg acttatttcc catttgtgaa
    16021 aatggcagat aaaactgaat tgagttaatg gtcttacttg cgttttttgt gataaaatag
    16081 aaatagatta cgtgtaagat tgagttaggt gtaggatttc ttatctccac taaaattgtt
    16141 attagacaaa ggtttatagt ttattgaagt tggaatagta cactgtaact tctaaaatag
    16201 tactagaaaa tgatttgaat ttcctaatcg atttagtcat attttagttc atttttctat
    16261 aaaacataac aagaatgtta ttgttttata tagagagatt gatatagaaa ggggtgcagt
    16321 aaaggtagat atcttcttgt gcctcttttg ccatattaga aaggagattt tatggttcag
    16381 acaaaacagc caaatattat tttgattgtt gtagatcaaa tgagagcaga cgccttatcc
    16441 ttgaatagta aggataagct agttagcact ccaacattag atatgatggc tagtgtaggt
    16501 tataattttg aaaatgccta ttctccagtt ccttcttgcg ttcctgctag ggcagcttta
    16561 ttgactggct tagaccaaga taaaagtgga cgagttggtt atcaagatga ggtgccttgg
    16621 aattttacta atactcttcc aaaagtcttt aaagatatgg gttatcaaac agagtgtatt
    16681 ggtaagatgc atgtttttcc ttccagacag agacttgggt ttgatcatgt cttacttcac
    16741 gatgggtatc tacatgttga tagaaagtat gataaggctt atggaagtca atttgattat
    16801 gctagtgact atctagcctt tttaaagggt aaagttggtt atgatgttga tttgattgat
    16861 gacggaatgg attgtaattc ttgggaagct agaccttggg ataaagatga gaagttacat
    16921 ccaacaaact gggttgtgag tgagtccatt tcatttttac aaagaagaga tccaacggtt
    16981 cctttttttc tcaaaatgtc ttttgaaaaa ccacatgctc cattaaatcc cccaaaatac
    17041 tattttgata tgtatatgga acgcttgcct caatttctcg atttgcatat cgggaattgg
    17101 gaagtattag aaaagcaaat tccgtctatt tatgctttaa gagggaaatt aaaggaagat
    17161 gatcaaagaa gaatggttgc tgcttatttt ggattgatta ctcatataga ccatcaaatt
    17221 agtcgctttt tgactgccct aaaagaattt cgtcatgata aagatacgat tatctggttt
    17281 gtttcggatc atggagatca gcttggtgaa cattatctgt ttagaaaggg atatccttat
    17341 cagggaagta tccacattcc ttcgtttatt tacgatccgg ctggattgat agctggtaat
    17401 aggggaacaa tcaagcaatt agtgaaaatt caagatattt ttccttcact cgtggatttg
    17461 gcaggaggaa ctactacaga tgaactagat ggacggagtg ttaagaattt attatttgga
    17521 cagtacgagg ggtggcgaac agaatttcat ggtgaacatg ctttaggaaa agattctagt
    17581 caatatatct tgacagacca gtggaaattt atctggtttc ctgttttaaa tcattatcag
    17641 ttatttgata tgaaaaaaga tccgcatgaa atgaatgatt tgtatccaag tgaaaaatac
    17701 caacctattg ttcgtcagat gaagaaaaaa ttagtagact ttcttagata tagagaagaa
    17761 ggttttgttg tggatgaaga gttagttcct gttgaacttt ctaaaataac gccaactcta
    17821 acgaaaacgg gggatagtca atcatgaaaa tgaaaaaaat caagggtggg acatttatga
    17881 tgggaacaaa ttctgaagag ggctttttag atgattttga aggtcctcaa gtcgctgtta
    17941 gtgtaaagga tttttccatt gcggatactc cagttacgaa tcaagaattt gctcaatttg
    18001 tgaaagaaac aggctataaa acactagctg agcgacaaga gtggtctttt gtttttatat
    18061 tgttcgttcc ggaggcagaa agggagggat atcctcatcc tgctggggct ccgtggtggt
    18121 tacaagtttc gaacgcttgc tggaaacatc cctacggtga gaacagtaat ctagtgggtt
    18181 tagaagacca tccagtagtt catgttgctt tagaagatgc attggctttc tgtaattgga
    18241 gcggaatgtc tttaccgact gaagcacagt gggaatatgc tgctagagga ggaagacaat
    18301 ctgaatatcc ttggggagat actcttttag aaggtggata ttatcatgcc aatacttggc
    18361 aaggaagatt tccttatgaa aatactgcct tagatggatt tataggaacg gctcctgtct
    18421 atgaattttt acctaatgat tttggtctat atcaaatgat tgggaatgtt tgggaatggt
    18481 gtcgcaatcc gagatatacc ttattagcta gttttaatga agatgactat gagttaccaa
    18541 aatatgggat acaagatgag gagtatgcta tcagaggagg ttccttttta tgtcattgtt
    18601 cttattgtaa tcgataccga gtagctgcta gaaatggatg tatttctact tccactagta
    18661 gccatctagg ttttagatgt ttgaaagaat aggatggact taaaaagtgg ttgagattat
    18721 ttattttcta atcattataa tagctagtgg attgggttct atatcaggca tgggtggtgg
    18781 aattataatt aagccactta tggatagttt tggataccat tcggtcagtg atattgcttt
    18841 ttattctagt ttctctgttt ttataatggc gattatttca acaatcaaaa gattttcaca
    18901 aagtaaagag ataaaatgga gattgatttt tacggtatcc ttttcttctg ttttaggagg
    18961 gtttctaggt catcttattt ttcaagtttt gttatctcaa ttatcagtac ggctagtatc
    19021 tattgttcaa atgattttac tatttgtgat gttacttgta tcatttgttt taacagattt
    19081 taaaaaaact tatcaatttg ataagatagg attctatatg atttgtggtc ttctattggg
    19141 cttgatttct agttttttag ggattggtgg tggtccgctc aatgtatctt tattgatggt
    19201 gtttttttct atttcgataa aagaagcaac gatgtattct cttgcaatta ttttcttttc
    19261 ccagttgtct catttggcta caattgttgt ggttacaggt ttaaatcagt atcatttagc
    19321 acctgttcca gttatttttc ttgcttctat atgcggaggg gtattgggga cggttgtatc
    19381 aaaagtctta cctgaaaatt gggtaagata ctgttttaaa gggatgttat tctttgtcat
    19441 gggaatgact ttatataatt tatttcatat tttgtaaggt cagtgtgaaa atatttaaat
    19501 agacttcctg taaaaactgg atttaacgcc ctccatttgt caaattaagc tagacagtct
    19561 taccaactca gaaaatacct gatgaggtat ttggtatcca aaggatttag gtgggatgtg
    19621 atttcttgag gctgggaaaa agtctttaaa attaaaaaat gtataatatc aggtgttgga
    19681 aaaactttga tactatgcgt tttattgtgg gaatatttat ttcattttct cctgaaattg
    19741 agtttttacc cagcctaaaa ttcttgactg acttcgttga aatctgtctg ctttggcaag
    19801 tcatgacacc ttaaaagtct atttgaatgt tcgttgagac accgctgtct tggacatcct
    19861 agattcgcaa aaaagctctc actatcgtga tgattggaaa tatctttcca ttttgaaaac
    19921 tcttttccac agtcaaacgt aatagattta aagaggttca ctagaaattg tgccagccac
    19981 ccttggatgg attctgccat atcctttgcc ttacgactct tggtcttcaa actgacaatc
    20041 aattgactat acctgttcgc tcacaaatag gagagaactg tttacgaaaa tctaatgaat
    20101 atgccacaag aacattatac cgcaacgtgt actatttttg gttcatttta ctatagaaac
    20161 tattgaagca cctgtacgaa aatatatcat gaaaaagggg agatagaaag caaacagcct
    20221 tgaaatcaat gttgactgcg attatgaacc tgaatcagcc cctcaaaaga gactgtatat
    20281 gaatgaacgt taccagtgtt taaaaactaa agaatatcag gcacttttat cttccaaggg
    20341 tagacaaatt ttcgctaaac gtaagattga tatgaaatct gtctttgggc agataaaggt
    20401 ttgtttgggt tataagagat gtcatctgag agggaagcgt caagtgagaa ttgacatggg
    20461 attcatactc atggccaaca acctgctgaa atataataag agaaagaggc aaaattaaaa
    20521 agctagagtt ccgcaattgg gaatctctag ctttttgttt tctgagaatc atcttgacta
    20581 atgttaccaa aaagataaag taacttttaa ccttatttat cgtcgccact caacatgttt
    20641 ttaacacctt ctacagcacc ttctacagcg tctttggcat cttcggcgac ttcttttact
    20701 ttagaaacaa ctttttcagc cgctccttct ttttccattt tttcatcacc gatggctttc
    20761 ccaacacctt ctttaataga acctttagct tgatttaatt tttcttctac tgacatgata
    20821 atttctcctg ttatatttat tttatcttag tttacacgag tgttttcgtg agatactaca
    20881 ccatttgctg cacctttaac agcttctaca ccttcgctaa ctttttcttg aacagttgag
    20941 aaaccagatc caagaccaga tttagctttt tcgaattgtt ctgaagtgaa ttctcctgtt
    21001 gattcagcaa cgtcagatac gcgatcttga aggcttactg agtctgcttc atgctgttct
    21061 ttagttttga tgtcgacaac gtttacgttg atttcaacaa tttccaagtc agtcatttta
    21121 gcaacttctg aagatacgat ttctctgatt tctgaatata aagctggaac atttttttgg
    21181 tactcaacaa taacgtttaa gtcaactgca acttgtgttt taccaacttc tacgttaaca
    21241 ccacttgtta cgtcatcgct gttaacgatt ttttctttaa gatttgagaa gaaaccacca
    21301 tcgattccca aaagacctga aacgttttct agtgaaagac caatgatttt ttggataact
    21361 ttatcttcgt aagtaagttc ccctttgatt tcgtgagcta caacagtagc atctttcttt
    21421 tctacgttag tgtttgtgtt tttttcgttt gacatatgaa actcctttaa ttaaattagt
    21481 aatttttatt tttttattta tctatatagt ttttttcgat atataatcca gctgcaactc
    21541 ccagtgctcc taaaatcaat acaaatattg ttttgaagaa gccaaaggag acaatcaaac
    21601 aagccagaaa tacgcctatg agaccagcga taattggata tcgatattgt ttaagccatt
    21661 ccatttttta cttccttact tcacacgact aacagtcttt ttgttttgag gttttggttg
    21721 gtaatttttt actgcaactt caagttttac ttgacgctca ataccaaaaa actgcttcaa
    21781 tccattagtt atttcatttt gaattatttg gcatctgtca gcgatgttgt ctgaaggaag
    21841 aattttacct tctacatgaa cgaaacattt attttttcgt aaatttacat gaacagttgg
    21901 gttcttgatc aatctatgat cactcaccaa acttctaaca aaaccttcga ttgccgaatt
    21961 ctttaatttt aatgtatcgt ttttagtttc aagttggatt tccaagtaac gtttaggata
    22021 aaacatcaca actaaaatgg ataataaaac taaagttgat agaaccactg tcccccaaaa
    22081 gacatatcta gcaagataga attcaactac ggagttctgt ctccagctaa gtagatgaat
    22141 acctagatca ctaacttgat gataatctat caaaacagga aggaaaattg tcaagattaa
    22201 aatacagaaa ataatgaaac atattttctt tgcttttgac atatacaatc ctttcgattt
    22261 aacatttaaa ctatttttcc cgtcattgat ttaaaaatag tttgctaact ttactggcga
    22321 aaagtttact ttctacctgt aaagaatgac actacagtaa tcacaatcgc tgcacctaca
    22381 atagatggga gcaaagccat tccagcgatt gatgaacccc aactacctaa aagagattgt
    22441 cctgcagatg ccccgactaa accagcgaat acatttgcga tgattcccat agaactactt
    22501 tttttagtga ttttacctgc caagagacca ataagacctc cagcaataat tgatcacaac
    22561 actgcctacc ctcctttttt attttaatat caaaaaatca atttctttga ttattactat
    22621 tatataactt taatatagaa aagtcaatta tttcgattgt tattattata taattttaaa
    22681 aaatcaaatt ctttaattgt tgctattata taatttttaa aattaaaaat ataatcttta
    22741 gacttgaatt tgattctgta ttcacgccct caatagacgg taaaataaga aaattgttta
    22801 tatattgtct ccgtagtgtt attatacgaa ataaaagatt ttaggaaaag tcgttatatc
    22861 atgctatacc tattctttgt ggtataattg caagaggttt aatccgataa tttataaaga
    22921 gagaaagata ttcatgagag atttattatc taaaaaaagt cataggcaat tagaattatt
    22981 agaattatta gaattattat ttgaacataa acgttggttt catcgttctg aactagcaga
    23041 gttattaaat tgtacagaac gtgcagtcaa agatgatcta tcccatgtta aatctgcttt
    23101 tcctgacttg atttttcatt cttctactaa tggtatacgc attattaata ccgatgatag
    23161 tgatattgaa atggtttacc atcatttctt taaacattca actcattttt cgattttaga
    23221 attcatcttc tttaatgaag gttgtcaagc tgagagtatt tgtaaagaat tttatatcag
    23281 ttcatcttcg ctctatcgta ttattagcca aatcaataaa gtgattaaaa ggcaatttca
    23341 atttgaagtc agtctgaccc ctgttcaaat cattggaaat gagagagaca ttcgttactt
    23401 ttttgcacaa tatttttcag aaaaatatta tttcctagaa tggccatttg aaaatttttc
    23461 atcagagcca ctatctcaat tgttagaatt ggtttataag gaaacaagct ttccaatgaa
    23521 tttgtcaacg catagaatgc taaagttgct cctagttacg aacctatata gaataaagtt
    23581 tggtcatttt atggaaatag ataaagattc ttttaacgac caaagtttgg attttttaat
    23641 gcaggcagaa ggaatagaag gtgttgctca gagttttgaa tcagaataca atatctcttt
    23701 agatgaagaa gttgtttgcc aattatttgt gtcttacttt caaaaaatgt ttttcataga
    23761 tgaaagtctc tttatgaaat gcgtaaaaaa ggatagttat gttgaaaaat cttaccatct
    23821 attgagtgat tttattgatc agatttcagt caagtatcag attgaaatgg agaataagga
    23881 taatctgatt tggcatctgc ataataccgc acatctgtat cgtcaagagt tgtttactga
    23941 gtttatttta tttgatcaaa aagggaatac aatcaggaac tttcaaaata tttttccaaa
    24001 atttgtttca gatataaaaa aagagctttc tcactattta gagactcttg aggtttgttc
    24061 tagttcaatg atggtaaatc atctatctta taccttcatc actcatacca aacatttggt
    24121 gattaatttg ctacaaaatc agcctaaact aaaggtttta gttatgagta attttgatca
    24181 gtatcatgca aaattcgttg cagagacact ttcttattac tgtagcaata attttgaact
    24241 ggaagtttgg actgaattag aattatcaaa ggaatcttta gaagattcat cttatgatat
    24301 cattatttct aattttatta ttcctcctat tgaaaataag agactcatct attcaaataa
    24361 tataaacacg gtctcactca tatatttgtt aaatgccatg atgtttattc gattagatga
    24421 gtaaccaaaa ataacaaaaa aacgctattt cgcgtttgaa ctgtacctca aaagttagac
    24481 agaaaaaatc taatttttgg ggtgtttttg ttaagaaaag accttcaatc atttaagcaa
    24541 aatgtacatc tagatttata gccctctaaa actcttgctt tttttgtaga agatacgaaa
    24601 aaagccataa aaccaaggct tttcctgttt tatgtagatg tttacacatg aaaattgaag
    24661 tattttcaaa agctaattgg agtgatttta ttcatgatgg gataaatgat ctggccaaaa
    24721 atgattgaga aatagttgct taaaaagcat ttgcatgata ctatatattg aaaggaggtg
    24781 ataatatggt agaacaaaga aaatcaatta ccatgaaaga tgttgcttta gaagcaggag
    24841 ttagtgttgg aactgtttca cgtgtaatta ataaagaaaa aggcattaaa gaagtaactt
    24901 taaggaaagt tcaaagggct ataaaaacat tggactatat ccctgataat tatgctcgag
    24961 gtatgaaaaa gaatagaaca gaaactatcg ctttgattat tccgagcata tggcatccat
    25021 ttttttcgga gtttgcctat catgttgaga aagagttatt aaaatataat tataaattat
    25081 ttatttgtaa cgctgatagc gattcacaaa atgaaatcga atatatcgaa atgttgaaac
    25141 aaaataaagt ggatggaatt attggtatta catattctga tattgacaaa tatattttat
    25201 ctgatttacc gtttgtaagt atagatagac atttttcgga aaatgtatgc tatgttactt
    25261 cagcaaatta caaaggagga caaactgcag cagaggaact ggttagaagg gataataagc
    25321 accttgcttt tattggttca attaatatgt atgagaatga gactatactc agaagtaaag
    25381 gattcagaga aaaagctaag gaattaggag tagatgtcta taattttgaa atgaaagaac
    25441 ctttaataaa tcctgaagat cagataagaa tttttttgca atctcataaa gaaattgatg
    25501 gtatatttac aataaatgat atgatggctc tgagagttat tagtgttatg aaagaactgg
    25561 ggaaaatagc acctgatgat taccagataa ttgggtttga tggtttaaaa acttctgtcg
    25621 atcaatctta tctagtgtct acaatagttc aagatattgg tatgatggca aaagaatctg
    25681 ttgcaatgat actgaaaatg attaagcgag aagagattct agaaaaacga atcgtaattc
    25741 ccacatattt ttggggagat aaaacaacaa aaaaaattta aaaagcgctt gacaattaat
    25801 gaaagcgctg ttataatata atcaacaaat gaaacgtttc aaaaataggc tagaagcttg
    25861 tttaaaaaat aaataaaaaa tgaaacgttt caaaaaggag gaaaatgatg cgtaaaggta
    25921 caatgttatc tgttgttgcg gggctatcgt tagctatact tgcaggttgt agtggaggaa
    25981 ctaactcaaa acaagcgagt tcttcaaatg atattaaagt ctgggtacaa ttctctgacg
    26041 aaacaaatga aggaaaagct tggcaaaaag ttgttgataa ctttaatcaa tcaggaaaaa
    26101 gtaagtacaa ggttgtaact gagtatattc ctcgtagtgg tggaggatat gaagacaagg
    26161 ttaatgctgc tattacgact aatagtcttc cagatgttat tacccttgat ggaccaaata
    26221 cggcagctta tgcaaaatct aaagtaatta ctccgctaga tgattatcta aaagataata
    26281 atatggatga tgttttggac agtattaaac aacagggaac ttataatggg aaattctatg
    26341 catttggatt ttctgaatcg aatgttggtg tttattacaa taaaaaaatg ttcaaagagg
    26401 ccggaattgc ggaatcagag cttccaacgc tagaaaagcc atggacatgg gacgaattta
    26461 atacgattgc taaaaaattg aaagatcatt ataacaaacc agcaattgat tttcgtatta
    26521 attcaaacga tgaaatgttg ccatatgctt atatgccgtt gatttggtca aataatggtt
    26581 ctgtcgtaaa cgaagatgga acaaaggcag aaggatactt caactccaaa gagagtgtag
    26641 aagcagttca attcattcaa aatcttgtaa aagaaggcta tacaactgtt agtccagtcg
    26701 aaaaaggttt tgaaacagga gagtatccaa tgcttttgag tggttcttgg acgattgctg
    26761 acatgaatac aaactacaaa gatattgatt ttggtatcct tccttaccca gtatctagta
    26821 agacgaaaaa attagtatcc ccttcaggta gttggcaatt agctgtgacg acaaaatctg
    26881 ataaaaaaga ggccgcatct gaatttgtta aatttgctac aaatacagaa tcaagtgaaa
    26941 ttattagctt ggggaattcg gtccttccaa ttcgtaaatc tacaattgaa aatatcaaag
    27001 ataaagtatc cgaaccaatg cgtttcttga tggaacaaaa ttcaaaaaca gctcatgctc
    27061 gcccagttgt tgtagcatat cctcaggttt ctcgagcttt tcaacaagca atgcaagata
    27121 ttagctatta tgaagaaaat ccaaatgtgc aaaaagtctt ggatactcgt acaaaagaaa
    27181 tgcaaactgc tattgatcag tcactcaaat aatctgtaaa aaagaaggtg gaaggaaaat
    27241 gtttggaact accttcccct ttcttgttaa tagcctagtt tgatatatat gattaaagga
    27301 gatggatatg agtaaagaaa ctgttgtgga tacaaaaaga cgtgaaaaaa taaaggataa
    27361 catattaggt tatagttttt tagctccagc tttaatttta ttaggtatct ttttagtaat
    27421 tccagttgga atggtcattt attacgcttt tacagattat tatttgttga caccagatga
    27481 aagaaaattt gttggacttg aaaattttat tcgattaaca aaagatccga ttttcttaaa
    27541 gagcttcttg aatactttga aatttgttgt ttggattatt ccagttcaat tgggagcggc
    27601 cttaggaatg gctttgattg tcaataaaaa gcgaaaagga aatatgtttt ttaaagtggc
    27661 tttttttgct ccagttgtca tgtccttggt agttatttct attctttggc tttatctttt
    27721 aaatccaaat agtggcttat taaatgctat tttaaataag gtaggtattg cttctcaacc
    27781 tttcttgact agtcctaaac aagctatgta tgcaattgtt tttgtttctg cttggcaggg
    27841 tgcaggttat cagatgcttt tatttttagg aggaatgcag aatattccac aagatgtcta
    27901 tgaagctgct gaattagatg gattctcaaa atgggctcag tttcgttata tcacgatgcc
    27961 cctactaaaa ccaacagccc tgtttgtatt gttaacaact ttaatttctg cttttaagct
    28021 gattgtacaa ccaatggtta tgacgcaagg tgggccatta aactcaacaa ttactatggt
    28081 gtactatatt tatcaacaag gttttactga tcgtcttgta ggatattcta gctcaatcgc
    28141 tttagtattt acaacgttaa ttggtatgat tagcttagta caacgtcgcg ttctgaagga
    28201 ggatgactaa gatgaaacga tttaaaccaa caacaatctt agaatatatt ctgttaactt
    28261 tattggcagg actcttcctt tttcctatgg tttggatggt agtttcagct atgaagccag
    28321 aagcagatgt ttataaaaat ttgactagtt ggcaagcctt cttaccaagt ttaaatcccg
    28381 ctgattggtt taaaccttat caggaagtat ttgagcgctt tagtattttt acatatctag
    28441 ggaacagcat tttttatgct ggaacgtttg ctattggttc tattattgtc aatgcactgg
    28501 ccggtttcgc ttttgcaaaa gtcaattttt caggtaagaa aattttattt ggtttcttac
    28561 ttgctttact tattattcca gtggaaactg tgttaattcc acaatttacc attatcaatt
    28621 ccttaggttt ggtcaataat cgtcttgcag ttattattcc aggattggcg agtgtattta
    28681 atatttactt atttaggaat ttctttattg caattccaga agagattctt gagtctgcaa
    28741 agatggacgg agcaagtatc gttagaattt tctttagaat tatgcttcca atgtctaaac
    28801 ctgcagttgc tacagttggt gttttatcat ttatttcaag ctggaatgat tatatctggc
    28861 cattgatggt tttgacagat tcttctaaat tttcaatgca ggttgcaatt acaactatta
    28921 atacaactca accagtttat atcaatcagg taatggctgt attaactatt tcaacgattc
    28981 cgttgatttt ggtctatgta gtcgctcaga aatatattgt tcaaggtctg ggtggttccg
    29041 gaactggaat aaaataggat atacttatga taaataaaac atttacagta gaaaaagcca
    29101 atcgttttat agcagaaaat aaacatctcg ttaatactca atataagcct gaagaacatt
    29161 tttcagctga gattggttgg atcaatgatc caaatggatt tgtttatttt cgtggagaat
    29221 accatctctt ttatcaattc tatccatatg atagtgtttg gggacctatg cactggggac
    29281 atgctaaaag taaggacttg gtgacttggg agcacttgcc agtggcactt gctcctgatc
    29341 aagattatga ccgaaatggt tgtttctcag gctctgccat tgtcaaggat gatcgcctct
    29401 ggctcatgta cactgggcat atcgaagaaa aaaccggtgt ccgccaagtg caaaatatgg
    29461 cattttcaga cgacgggatt cactttgaaa agattgaaca aaatccagtt gcaacaggag
    29521 cagacttgcc agatgagttg attgctgctg atttccgtga tccaaaactc tttgaaaaag
    29581 atggacgcta ttactccgta gtagctgcca aacacaagga taatgtgggc tgtatcgttc
    29641 tactagggtc cgataaccta gtagaatggc agttcgaatc catcttttta aaagggggag
    29701 aacaccaagg ctttatgtgg gaatgcccag attacttcga gttagatggg aaagattgcc
    29761 ttattatgtc acccatgcgt tatcagcgtg agggagactc atatcataac atcaactcat
    29821 cgcttttgtt cacgggtaag gtagattggg gagaaaaacg ttttatccca gaatcagttc
    29881 aagaaattga tcatggccaa gacttctatg cgcctcaaac attgttggac gatcaaaatc
    29941 gtcgtatcct gattgcttgg atgcagacat gggggcgtac ccttccaact catgaccaag
    30001 aacacaagtg ggcatgtgcc atgactttac ctagaattct aagattggaa gatggcaaac
    30061 taagacaatt ccctgttaaa aaaggccaat atcaaatcca aatagataaa gattgtcatt
    30121 accacttagg aaatgataca gattatcttg aatttggtta tgacagtaat gtgcagcaag
    30181 tttacattga tcgtagccat cttattcaaa aaattctagg tgaagaagaa caggacacta
    30241 gtcgacggta tgtagatatt gaagctaaag aattggaagt tgttctagat aaaaattcca
    30301 tcgagatttt tgtcaatcaa ggtgaagcaa gcttgactgc aacttattac ttaacggtgc
    30361 cagctgagct atcacgaatt gattaaaaat taagttattt ctcctaaaga aaaagttctc
    30421 tttctaaaat agtggaaaga ggactttttg tgttttgggt atataagctt agtttatggt
    30481 atttgtaaaa ttggtgttgg attatgattt aaactagttt tctaaagaat ttgaaaaaaa
    30541 ttttatttaa gcaaaaaaag ccctatatta taagactttt cctgttgtat ttatatgccc
    30601 cctacaggga tcgaacctgt gacccacgga ttaagagtcc gctgctctgc cagctgagct
    30661 aaggaggcaa agaaaaaagc tgtattggtg ccgaaacttc acggtttgta ttgaacccgc
    30721 gcaattaagc aggtgggcaa ctcgctctaa ctgaagctgt ttccgtgtga gacggcctac
    30781 atgctgttag aagacttttg tttccctaat aatacaaaaa atagtcggtc aacacttaag
    30841 tgtgaagtcg tacaccacag cgtttctata cttatatgat accacttttt caaaaaaaat
    30901 caagaggaaa gtgcaatttt ttgaaaagga tttcagattt ttcgcaaacg atcgatagct
    30961 tcctttcttt gagccaaagc ccgttcatat ttaccagtat cttctgcttg gaaatagtga
    31021 tgattacgaa ttttttctgg cagatagtct tgcttgatcc aatttccagg atagttgtgt
    31081 ggatagagat agtcttgggc attccccagt tccttgcttc cactgtagtg cccatcacgc
    31141 aggtgtcgcg gaataggcaa gtgccctgat gttttgaggt cagcaagtgc cttatccata
    31201 gctacatagg ctgagttgga ttttggagaa agggccaaat caatcacgac attggcaatg
    31261 agaatgcggg cttctgggaa cccaatcttc tgggcagcat ccagagcagt cacggtatga
    31321 atctgggcct caggattggc taagccgata tcttcatagg cgataacagt caagcgacga
    31381 gcgagactag gcagatcccc agcctcaatc aagcgggcag tatagtggag actggcatcc
    31441 acatctgagc cacgaataga cttttgcagg gcagatagaa catcatagtg accgtctcca
    31501 tccttgtcca tagtgatgta gcttctctga agactatttt ccatgatgtc taaggtgatg
    31561 tggcgaatgc cctcgtcatt ctcaggggta gagagaacag ccaagtccag tgagttaaag
    31621 gcagagcgaa ggtctccgtt tgtagaggtt gcgatgaaat ccagcgcatc ctcatctagt
    31681 tctattggaa aatcaaaacc acgttcaggg ttacttagag ctatctgcag ggcctctttg
    31741 acgtcttggt tagacagagg ttccaactcg aaaatttgaa cacggctacg aatggcagga
    31801 gtgacagaga agaaaggatt ttcagtcgtt gctccaatca tgatgaccag tccactttcc
    31861 aagagaggca agaggaagtc ttgcttggtc ttatctagtc gatgaatttc gtctagcaat
    31921 aggacgagac caccagaaaa tttagcttct tccgagattt cttgcagtcg ctttttacta
    31981 tcaactgtcg cattgaaagt tcgaaaggca tacttggtcg ttccagcgat ggcagaggca
    32041 atactggttt tgccgattcc cggagggcca tatagaatca tggaggacag gcggttggct
    32101 tccaccatgc ggcggatgat ttttccaggt ccgaccagat gctcctgacc gatgacctgg
    32161 tcgatggttt tagggcgcat gcgaagcgcg agattgtctg gcatagcagt cctttctaac
    32221 gtggatttga gtagaatgac tcatctacta tatcttacta tgtccattct agcctattag
    32281 ttgtgatatt tcaatggttt tgtaataatc agggagtgag atagaatctt ttttactatt
    32341 taatttaatg aggagaggta tcagcatgag agatttgatt ttccttaaag ctcaaaatag
    32401 gatagttgag cctaaagaag tggaagtgct gacttgagaa ataatattgc tgaatgtcat
    32461 tgtatgaact ataatgaaaa gagaggtgat aagcaatgga aatgatggac caagtcagga
    32521 aattttgatt tttacaaaac aaattcgtca ttggattctt agtgatcaag ttatttcagg
    32581 gaaaagaaaa cttttcttcc gggaagatac tccaaaagag attttagatt tgtacgaaaa
    32641 cattaaatct aaacttgatt ttgcttacca agaagttcat tctaataatg ggttgaaaaa
    32701 atatgaaaaa tagaataatt gatgttttga agtagtaaat cgcctccttg tactaactgt
    32761 tgaaaatcct gatttcgaag acttgagagt taat
//
LOCUS       DBERXF010000023        32133 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.23, whole genome shotgun sequence.
ACCESSION   DBERXF010000023 DBERXF010000000
VERSION     DBERXF010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32133
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.23"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            198..2180
                     /locus_tag="ACL8JK_001201"
     CDS             198..2180
                     /locus_tag="ACL8JK_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1786092.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSAKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEEFNKKAQEDLAKHVK"
     gene            2481..7784
                     /locus_tag="ACL8JK_001202"
     CDS             2481..7784
                     /locus_tag="ACL8JK_001202"
                     /EC_number="3.2.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033926 -
                     endo-alpha-N-acetylgalactosaminidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpGH101 family
                     endo-alpha-N-acetylgalactosaminidase"
                     /protein_id="HGS1786093.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPVAAKPETPKTVTPEWQTVEKKEQQGTVAIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDEAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKVTFLVTGAETGD
                     TWVGIYSTGNASNTRSDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKSKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(7951..10110)
                     /gene="pbp1a"
                     /locus_tag="ACL8JK_001203"
     CDS             complement(7951..10110)
                     /gene="pbp1a"
                     /locus_tag="ACL8JK_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HGS1786094.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(10107..10703)
                     /gene="recU"
                     /locus_tag="ACL8JK_001204"
     CDS             complement(10107..10703)
                     /gene="recU"
                     /locus_tag="ACL8JK_001204"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGS1786095.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10769..11296
                     /locus_tag="ACL8JK_001205"
     CDS             10769..11296
                     /locus_tag="ACL8JK_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGS1786096.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            11366..11695
                     /gene="gpsB"
                     /locus_tag="ACL8JK_001206"
     CDS             11366..11695
                     /gene="gpsB"
                     /locus_tag="ACL8JK_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGS1786097.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11716..12096
                     /gene="rnpB"
                     /locus_tag="ACL8JK_001207"
     ncRNA           11716..12096
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACL8JK_001207"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12181..13338
                     /locus_tag="ACL8JK_001208"
     CDS             12181..13338
                     /locus_tag="ACL8JK_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGS1786098.1"
                     /translation="MKKEFNLIATAAAGLEAVVGREVRELGYDCQIENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13351..14721
                     /gene="mapZ"
                     /locus_tag="ACL8JK_001209"
     CDS             13351..14721
                     /gene="mapZ"
                     /locus_tag="ACL8JK_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HGS1786099.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDANAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQASSNTTS
                     EPKPSSSNETRSSRSEVNMGLSSEGVAVQRSASRVAYNQSAIDDSNNSAWDFADGVLE
                     QILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGYFVGNGAGH
                     ADDLDY"
     gene            14797..16221
                     /gene="gndA"
                     /locus_tag="ACL8JK_001210"
     CDS             14797..16221
                     /gene="gndA"
                     /locus_tag="ACL8JK_001210"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGS1786100.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16233..16922
                     /locus_tag="ACL8JK_001211"
     CDS             16233..16922
                     /locus_tag="ACL8JK_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1786101.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            17020..17985
                     /gene="cbpC"
                     /locus_tag="ACL8JK_001212"
     CDS             17020..17985
                     /gene="cbpC"
                     /locus_tag="ACL8JK_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HGS1786102.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKLAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWKYVRGKWYYLDNKNGDMKTGWYQDGSTWYYLDPS
                     NGDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            18004..19002
                     /gene="cbpJ"
                     /locus_tag="ACL8JK_001213"
     CDS             18004..19002
                     /gene="cbpJ"
                     /locus_tag="ACL8JK_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HGS1786103.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKELEIKTQDSVGRKYGEKRENSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYIGGERRAGWINDASAWYYLDPATGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNMTVDGYSVNYNGEWVR"
     gene            complement(19120..20352)
                     /locus_tag="ACL8JK_001214"
     CDS             complement(19120..20352)
                     /locus_tag="ACL8JK_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS1786104.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEVVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFSLLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(20363..20815)
                     /locus_tag="ACL8JK_001215"
     CDS             complement(20363..20815)
                     /locus_tag="ACL8JK_001215"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786105.1"
                     /translation="MFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKGISGIILY
                     LCMYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVI
                     LACSERDDHGLLMFQGDSGKADLFDFGIGSMGVYWCLLNNKFPFDVQT"
     gene            complement(20883..21271)
                     /locus_tag="ACL8JK_001216"
                     /pseudo
     CDS             complement(20883..21271)
                     /locus_tag="ACL8JK_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
     gene            21882..22211
                     /locus_tag="ACL8JK_001217"
     CDS             21882..22211
                     /locus_tag="ACL8JK_001217"
                     /inference="COORDINATES: protein motif:HMM:NF024736.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1786106.1"
                     /translation="MTRKVYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
     gene            22333..23211
                     /gene="mvk"
                     /locus_tag="ACL8JK_001218"
     CDS             22333..23211
                     /gene="mvk"
                     /locus_tag="ACL8JK_001218"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGS1786107.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            23193..24146
                     /gene="mvaD"
                     /locus_tag="ACL8JK_001219"
     CDS             23193..24146
                     /gene="mvaD"
                     /locus_tag="ACL8JK_001219"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGS1786108.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEVVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            24133..25140
                     /locus_tag="ACL8JK_001220"
     CDS             24133..25140
                     /locus_tag="ACL8JK_001220"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGS1786109.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            25124..26134
                     /gene="fni"
                     /locus_tag="ACL8JK_001221"
     CDS             25124..26134
                     /gene="fni"
                     /locus_tag="ACL8JK_001221"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGS1786110.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SSQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            26212..26910
                     /gene="liaF"
                     /locus_tag="ACL8JK_001222"
     CDS             26212..26910
                     /gene="liaF"
                     /locus_tag="ACL8JK_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGS1786111.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAVTILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            26907..27902
                     /locus_tag="ACL8JK_001223"
     CDS             26907..27902
                     /locus_tag="ACL8JK_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS1786112.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDQDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            27916..28548
                     /locus_tag="ACL8JK_001224"
     CDS             27916..28548
                     /locus_tag="ACL8JK_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS1786113.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF"
     gene            28549..28790
                     /locus_tag="ACL8JK_001225"
                     /pseudo
     CDS             28549..28790
                     /locus_tag="ACL8JK_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            28772..29317
                     /locus_tag="ACL8JK_001226"
                     /pseudo
     CDS             28772..29317
                     /locus_tag="ACL8JK_001226"
                     /inference="COORDINATES: protein motif:HMM:NF020296.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            29467..29706
                     /locus_tag="ACL8JK_001227"
     CDS             29467..29706
                     /locus_tag="ACL8JK_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786114.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            29787..30608
                     /gene="cbpG"
                     /locus_tag="ACL8JK_001228"
     CDS             29787..30608
                     /gene="cbpG"
                     /locus_tag="ACL8JK_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HGS1786115.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKNAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSAVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYYYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNRAMVTGSQTIDGKVYNFASSGEWI"
     gene            30627..31649
                     /gene="cbpF"
                     /locus_tag="ACL8JK_001229"
     CDS             30627..31649
                     /gene="cbpF"
                     /locus_tag="ACL8JK_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HGS1786116.1"
                     /translation="MKLLKKMMQVVLATFFFGLLGTSTVFADDSVGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEISLRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPATGI
                     MQTGWQYLGNKWYYLHSSGAMATGWYKEGSTWYYLDAENGDMRTGWQNLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(31777..32133)
                     /locus_tag="ACL8JK_001230"
                     /pseudo
     CDS             complement(31777..32133)
                     /locus_tag="ACL8JK_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         9902 a         5722 c         7288 g         9221 t
ORIGIN      
        1 aaatctccag attaggaact atccgtgagt tctctagtct ggagattttt caatatactt
       61 cgttattgga cggttacgat attcatattt tttgcaaaga tgttgtttga aaaataattt
      121 tcaaaaattc tgaaaattct gttgacaact ttctgaaaag agtctataat ggagagaaag
      181 ttttaaagga gaaaatgatg aaaagttcaa aactacttgc ccttgcgggc gtgacattat
      241 tggcggcgac tactttagct gcatgctctg gatcaggttc aagcgctaaa ggtgagaaga
      301 cattctcata catttatgag acagaccctg ataacctcaa ctatttgaca actgctaagg
      361 ctgcgacagc aaatattacc agtaacgtgg ttgatggttt gctagaaaat gatcgctacg
      421 ggaactttgt gccgtctatg gctgaggatt ggtctgtatc caaggatgga ttgacttaca
      481 cttatactat ccgtaaggat gcaaaatggt atacttctga aggtgaagaa tacgcggcag
      541 tcaaagctca agactttgta acaggactaa aatatgctgc tgataaaaaa tcagatgctc
      601 tttaccttgt tcaagaatca atcaaagggt tggatgccta tgtaaaaggg gaaatcaaag
      661 atttctcaca agtaggaatt aaggctctgg atgaacagac agttcagtac actttgaaca
      721 aaccagaaag cttctggaat tctaagacaa ccatgggtgt gcttgcgcca gttaatgaag
      781 agtttttgaa ttcaaaaggg gatgattttg ccaaagctac ggatccaagt agtctcttgt
      841 ataacggtcc ttatttgttg aaatccattg tgaccaaatc ttctgttgaa tttgcgaaaa
      901 atccgaacta ctgggataag gacaatgtgc atattgacaa agttaaattg tcattctggg
      961 atggtcaaga taccagcaaa cctgcagaaa actttaaaga tggtagcctt acagcagctc
     1021 gtctctatcc aacaagtgca agtttcgcag agcttgagaa gagtatgaag gacaatattg
     1081 tctatactca acaagactct attacgtatc tagttggtac aaatattgac cgtcagtcct
     1141 ataaatacac atctaagacc agcgacgaac aaaaggcatc gactaaaaag gctctcttaa
     1201 acaaggattt ccgtcaggct attgcctttg gttttgatcg tacagcctat gcctctcagt
     1261 tgaatggaca aactggagca agcaaaatct tgcgtaatct ctttgtgcca ccaacatttg
     1321 ttcaagcaga tggtaaaaac tttggcgata tggtcaaaga gaaattggtc acttatgggg
     1381 atgaatggaa ggatgttaat cttgcagatt ctcaggatgg tctttacaat ccagaaaaag
     1441 ccaaggctga atttgctaaa gctaaatcag ccttacaagc agaaggtgtg acattcccaa
     1501 ttcatttgga tatgccagtt gaccaaacag caactacaaa agttcagcgc gtccaatcta
     1561 tgaaacaatc cttggaagca actttaggag ctgataatgt cattattgat atccaacaac
     1621 tacaaaaaga cgaagtaaac aatattacat attttgctga aaatgctgct ggcgaagact
     1681 gggatttatc agataatgtc ggttggggtc cagactttgc cgatccatca acctaccttg
     1741 atatcatcaa accatctgta ggagaaagta ctaaaacata tttagggttt gactcagggg
     1801 aagataatgt agctgctaaa aaagtaggtc tatatgacta cgaaaaattg gttactgagg
     1861 ctggtgatga ggctacagat gttgctaaac gctatgataa atacgctgca gcccaagctt
     1921 ggttgacaga tagtgctttg attattccaa ctacatctcg tacagggcgt ccaatcttgt
     1981 ctaagatggt accatttaca ataccatttg cattgtcagg aaataaaggt acaagtgaac
     2041 caatcttata taaatacttg gaacttcaag acaaggcagt cactgtagat gaataccaaa
     2101 aagctcagga aaaatggatg aaagaaaaag aagagtttaa taaaaaggct caagaagatc
     2161 tcgcaaaaca tgtgaaataa ctgttgcaaa atataagaaa ggatttagta tttctcttga
     2221 atgctgaatc cttttttaca tttgtaaaga aagattctaa atgtactgac ccccaaaagt
     2281 tggagcctct ttttgtcaga atagagaaaa tttttgttaa ttttacttgt ttcctattgc
     2341 tttctcagct attatttgtt atattaaaag cataattatt ttttatttat cagggttaag
     2401 cattgcactt tcagaggaag gagtattttt taaaaagaaa atgtaaacgc ttgctcaaaa
     2461 atgaaaggat ttagaagttt atgaataaag gattatttga aaaacgttgt aaatatagta
     2521 ttcggaaatt ttcattaggt gttgcttctg ttatgattgg agctgcattc tttgggacaa
     2581 gtccggttct tgcagatagc gtgcagtctg gttccacggc gaacttacca gctgatttag
     2641 ctactgctct tgcaacagca aaagagaatg atgggcgtga ttttgaagcg cctaaggtgg
     2701 gagaagacca aggttctcca gaagttacag atggacctaa gacagaagaa gaactattag
     2761 cacttgaaaa agaaaaaccg gctgaagaaa aaccaaaaga ggataaacct gtagctgcta
     2821 aacctgaaac acctaagacg gtaacccctg aatggcaaac ggtagagaaa aaagaacaac
     2881 agggaacagt cgctatccga gaagaaaaag gtgtccgcta caaccaacta tcctcaactg
     2941 ctcaaaatga taacgcaggc aaaccagccc tgtttgaaaa gaagggcttg accgttgatg
     3001 ccaatggaaa tgcaactgtt gatttaacct tcaaagaaga ttctgaaaag ggcaaatcac
     3061 gctttggtgt cttcttgaaa tttaaagata ccaataataa tgtttttgtc ggttatgaca
     3121 aggatggctg gttctgggag tataaatctc caacaactag cacttggtat agaggtagtc
     3181 gtgttgctgc tcctgaaaca ggatcaacaa accgtctctc tatcactctc aagtcagacg
     3241 gtcagctaaa tgccagcaat aacgatgtca atctctttga cacagtgact ctaccagctg
     3301 cggtcaatga ccatcttaaa aatgagaaga agattcttct caaggcgggc tcttatgacg
     3361 atgagcgaac agttgttagc gttaaaacgg ataaccaaga gggggtaaaa acagaggata
     3421 cccctgctga aaaagaaaca ggtccggttg ttgacgatag caaggtgact tatgacacga
     3481 ttcagtctaa ggtcctcaaa gcagtgattg accaagcctt ccctcgtgtc aaggaataca
     3541 gcttgaatgg acatactttg ccaggacagg tgcaacagtt caaccaagtc tttatcaata
     3601 accaccgaat cacccctgaa gtcacttata agaaaatcaa tgagacaaca gcagagtact
     3661 tgatgaagct tcgcgatgat gctcacttaa tcaatgcgga aatgacagta cgcttgcaag
     3721 ttgtggacaa tcaattgcac tttgatgtga ccaagattgt caaccacaat caagtcactc
     3781 caggtcaaaa gattgatgac gaaagaaaac tactttcttc tattagtttc ctcggcaatg
     3841 ctttagtctc tgtttctagt gatcaaactg gtgctaagtt tgatggggca actatgtcaa
     3901 acaatacgca tgtcagtgga gatgatcata tcgatgtaac caatccaatg aaagacctag
     3961 ccaagggtta catgtatgga tttgtttcta cagataagct tgctgctggt gtttggagta
     4021 actctcaaaa cagctatggt ggtggttcga atgactggac tcgtttgaca gcttataaag
     4081 aaacagtcgg aaatgccaac tatgtaggaa tccacagctc tgaatggcaa tgggaaaaag
     4141 cttataaggg cattgttttc ccagaataca cgaaggaact tccgagtgct aaggttgtta
     4201 tcactgaaga tgccaatgca gacaagaaag ttgattggca agatggtgcc attgcttatc
     4261 gtagcattat gaacaaccct caaggttggg aaaaagttaa ggatatcaca gcttaccgta
     4321 tcgcgatgaa ctttggttct caagcacaaa atccattcct tatgaccttg gatggtatca
     4381 agaaaatcaa tctccacaca gatggtcttg ggcaaggtgt tctccttaaa ggatatggta
     4441 gcgaaggcca tgactctggt cacttgaact atgctgatat tggtaagcgt atcggtggtg
     4501 tcgaagactt caagactcta attgagaagg ctaagaaata tggagctcat ctaggtatcc
     4561 acgttaacgc ttcagaaact tatcctgagt ctaaatactt caatgaaaaa attctccgta
     4621 agaatccaga tggaagctat agctatggtt ggaactggct agatcaaggt atcaacattg
     4681 atgctgccta tgacctagct catggtcgtt tggcacgttg ggaagatttg aagaaaaaac
     4741 ttggtgacgg tctcgacttt atctatgtgg acgtttgggg taatggtcaa tcaggtgata
     4801 acggtgcctg ggctacccac gttcttgcta aagaaattaa caaacaaggc tggcgctttg
     4861 cgatcgagtg gggccatggt ggtgagtacg actctacctt ccatcactgg gcagctgact
     4921 tgacctacgg tggctacacc aataaaggta tcaacagtgc catcacccgc tttatccgta
     4981 accaccaaaa agatgcttgg gttggggact acagaagtta tggtggtgca gccaactatc
     5041 cactgctagg tggctacagc atgaaagact ttgaaggctg gcaaggaaga agtgactaca
     5101 atggctacgt gactaacctc tttgctcatg acgtcatgac taagtacttc caacacttca
     5161 ctgtaagtaa atgggaaaat ggtacaccgg tgactatgac cgataacggt agcacctata
     5221 aatggactcc agaaatgcga gtggagttgg tagatgctga caataataaa gtagttgtaa
     5281 ctcgtaagtc aaatgatgtc aatagcccac aatatcgcga acgtacagta acgctcaacg
     5341 gacgtgtcat acaagatggt tcagcttact tgactccttg gaactgggat gcaaatggta
     5401 agaaactttc tactgagaag gaaaagatgt actacttcaa tacgcaggcc ggtacaacaa
     5461 cttggaccct tccaagcgat tgggcaaaga gcaaggttta cctttacaag ctaactgacc
     5521 aaggtaagac agaagagcaa gaactaactg taaaagatgg taaaattacc ctagatcttc
     5581 tagcaaatca accatacgtt ctctatcgtt cgaaacaaac caatcctgaa atgtcatgga
     5641 gtgaaggcat gcacatctat gaccaaggat ttaatagcgg taccttgaaa cattggacca
     5701 tttcaggcga tgcttctaag gcagaaattg tcaagtctca aggggcaaac gatatgcttc
     5761 gtattcaagg aaacaaagaa aaagttagtc tcactcagaa attaactggc ttgaaaccaa
     5821 ataccaagta tgccgtttat gtcggtgtcg ataaccgtag taatgccaag gcgagcatca
     5881 ctgtaaacac tggtgaaaaa gaagtgacta cttataccaa taagtctctc gccctcaact
     5941 atgttaaggc ctacgcccac aatacacgtc gtaacaatgc tacagttgac gatacaagtt
     6001 acttccaaaa catgtacgcc ttctttacaa ctggatcgga cgtatcaaat gttactctga
     6061 cattgagtcg tgaagctggt gatgaagcaa cttactttga tgaaattcgt acctttgaaa
     6121 acaattcaag catgtacgga gacaagcatg atacaggtaa aggcaccttc aagcaagact
     6181 ttgaaaatgt tgctcagggt atcttcccat ttgtagtggg tggtgtcgaa ggtgtcgaag
     6241 acaaccgcac tcacttgtct gaaaaacacg atccatatac acaacgtggt tggaatggta
     6301 agaaagtcga tgatgttatc gaaggaaatt ggtcactcaa gacaaatgga ctagtgagtc
     6361 gtcgtaactt ggtttaccaa accatcccac aaaacttccg ctttgaagct ggtaagacct
     6421 accgtgtaac ctttgaatac gaagcaggtt cagacaatac ctatgctttt gtagtcggta
     6481 agggagaatt ccaatcaggt cgtcgtggta ctcaagcaag caacttggaa atgcatgaat
     6541 tgccaaatac ttggacagat tctaagaaag ccaagaaggt aaccttcctt gtgacaggtg
     6601 cagaaacagg ggatacttgg gtaggtatct actcaactgg caatgcaagt aatactcgta
     6661 gtgattctgg tggaaatgcc aacttccgtg gttataacga cttcatgatg gataatcttc
     6721 aaatcgaaga aattacccta acaggtaaga tgttgacaga aaatgctctg aagaactact
     6781 tgccaacggt tgccatgact aactacacca aagagtctat ggatgctttg aaagaggcgg
     6841 tctttaacct cagtcaggcc gatgatgata tcagtgtgga agaagcgcgt gcagagattg
     6901 ccaagattga agccttgaag aatgctttgg ttcagaagaa aacggctttg gtagcagatg
     6961 actttgcaag tcttacagct cctgctcagg ctcaagaagg tcttgcaaat gcctttgatg
     7021 gaaacttatc tagtttatgg catacatcat ggggcggagg agatgtaggc aagcctgcaa
     7081 ccatggtctt gaaagaacca actgaaataa ctggacttcg ttatgttcca cgtggatcag
     7141 gttcaaatgg taacttgcgt gatgtgaaac ttgttgtgac agatgagtct ggcaaggagc
     7201 atacctttac tgcaactgat tggccagata acaataagtc aaaagatatt gactttggta
     7261 agacaatcaa ggctaagaaa attgtcctta ctggtaccaa gacttacgga gatggtggcg
     7321 ataaatacca atctgcagcg gaactcatct ttactcgtcc acaggtagca gaaacacctc
     7381 ttgacttgtc aggctatgaa gcagctttgg ctaaggctca gaaattaaca gacaaagaca
     7441 atcaagagga agtagctagc gttcaggcaa gcatgaaata tgcgacggat aaccatctct
     7501 tgacggaaag aatggtggaa tactttgcag attatctcaa ccaattaaaa gattctgcta
     7561 cgaaaccaga tgctccaact gtagagaaac ctgagtttaa acttagctct ttagcttccg
     7621 atcaaggtaa gacgccagat tataagcaag aaatagctag accagaaaca cctgaacaaa
     7681 tcttgccagc aacaggtgag agtcaatctg acacagccct cttcctagca ggtgttagcc
     7741 tagccctatc tgctctcttt gtagtaaaaa cgaagaaaga ctagtattta gtaaaacctc
     7801 ttaacaagat tacggaagca gtctctatct tttccaatga ggtttatagt acagaaaaag
     7861 cctgagaaga tgtcttctca ggcttttgtt aagcacataa atacaatagt gctatgacaa
     7921 aatcacctag aaaaatctgg gtgataaatg ttatggttgt gctggttgag gattctgatt
     7981 ttgttgatca ggggttgtat ttgattgttg cgtattattg ttaggattgg tagtcgtact
     8041 attatttgtg cttggagtgg ttgagctaga ctgtgaagtt gaactatctg atgatgagct
     8101 tgaactttca gttgatgggg gttgttgtgg agcaggtgag ttccacgtag aacgagcacc
     8161 atttttaaat acgaattctc catttctgta gagcccctct ggtatattcc aatcttctgg
     8221 attgcttcct tcagacaggt aggtcatcat agagcggtaa actttggcag cgaccgtaag
     8281 gccattgcct acaagtggtg tcagacggtt agaatagcct gtccatacag ccattgaata
     8341 tttacgcgta tagccagcaa atagttcatc aggtgctaca aattgagagg tcttgatgtg
     8401 gttttcaatt tcctcgtctg tatagttaga ggttcctgtt ttaccagcct gaggaagcca
     8461 agcaagatag gcatttcgtc cagttccata agtcaagact gttttcatca tgtcggtcat
     8521 catataggct gtcgtttctt tcatggcacg agttccgaca ttagagaact ctttttcact
     8581 cccatcacta aagacgactt tatggatata cattggttta tagtaagttc caccatttgc
     8641 aaaggcagcg taagcagcag ccatcttttc actacttgct ccatattttt tgtctgattc
     8701 ggttgtgtta cttgaaatgg catttgagta gtgaatactt gggtagtcga ttccgagacc
     8761 atttaggaaa gtcttggcgc ggttgagtcc gaccttgttt agagtttcca cggctgggac
     8821 gtttcgcgat tgttgcaggg cgtattgcaa ggtgatgttg ccaaagtagc ccctatccca
     8881 gttataaaca ggagtatttg tcccagggta attatagggc tcatcgtgaa cgatagtagc
     8941 agttgaatcg tagacaccgt actccaaggc aggagcatag tctgtgatcg gtttcatagt
     9001 tgatccccag tcgcggtttg tttctactgc ttggttaatt ccgaaggaaa cattacttga
     9061 ctgatggcgt gctcctagct gggcaatgac tttaccgtta gaaacatcaa caatggtaga
     9121 agcgacttgc aattcatcgt ctggataggc aacgtattcg tctgtattgt aaatatccca
     9181 cagatgtttt tgagcttctt ggtctacatt tgtgtagaca tccatcccag ttgtgagcag
     9241 gttatagcct gtttcttctt caacttgatt gatgacttcc ttgaggtaat tatccatgta
     9301 agcagggtaa ttacttgctg atttgagact ttgtagtcca tcagtaattg gtgtattgac
     9361 tgctttctca tactgttcag cagagatgta gccttgattt ttcatttcag ataagaccaa
     9421 gtttcggcgg tcttgggctg cttctggatg tgaatagggg tcatattggt ttggtgcctg
     9481 aggcattcca gccagcaagg ctaactgagg taaacttaaa ttattgaggt ctttaccata
     9541 gtagttttga gctgctgtct gcattccata gttcccatta gacatgtaga ccttatttat
     9601 atagtaggtc aagatttctt gcttggttgc tttttgttct aactgaatcg ctaaccaagc
     9661 ttcctgagcc ttacgagaaa tagtctggtc ggaagtcgaa gttgaaaagt aagtcaactt
     9721 aatcaactgt tgggtgagag ttgatccacc ttggagggaa ttgctttgca gattgcgcaa
     9781 gaaagctccc aggatacgga tggtatcaat ccccctgtgg tcgaagaagc gatggtcttc
     9841 gatagaaacg attgccttaa ccaaatctgt gggaatatca ttagcttggg cattgacgcg
     9901 gcgttcagaa cccaagtcag caatgagttg atttttattg tcgtagattt tactagaagt
     9961 tgttgcaact agtttactct cggataggct aggagccttg ctaacgtagt agaaaaaaac
    10021 tcctccgcct aagacaatgg ctgcgataac caagcttaag aagctaatgc tcagatactt
    10081 gattaggcgc agaatcgttg gtttgttcat cttgttttac cacctaataa atgttctttg
    10141 ataacattga gataaggaat ttgagggaag gcaccagcct tgatttcata tccatattct
    10201 cgaatatatt caagtggcat tgatttttgt cccttatctt gatgatagaa gcgaatcaaa
    10261 tcgaatgccg gcaataagta ggtttcttgc tgagaagaaa agtgaagaag gacaaagcag
    10321 attccttgtt gggcaaggac ttgttccata tgctgaatct gatgtggatg aaaatttttc
    10381 atcggaatcg cacgtttttg ttttgtttcc ttgacttcaa agtcgatgta atatccatta
    10441 taaacgccag aatagtccgt cgttgaagct tgtcgaaaat aggcttcaac aatcttggca
    10501 cgacttcgtt gtggatagtc cacttgtacg atttgaatag gagttggttt cttatgtata
    10561 acagccaagc cctgagacaa atagtagtcg ttggtagcat tgatcatctt ttcaaaagac
    10621 attcctcgat ttgcgaaatt tttgggttga gaaagagatg tttgtctttt ttgtgatgaa
    10681 actttatgtg gatagttgac cataattctc cttattggta caataacatc actttattat
    10741 accataattt gcacagaaag ggttaaaaat ggctacagct ttggttttag gctattctgc
    10801 ttttgatttg ggtttatttt ctgataagga tcctcgtctt aaattgatta aaaaagcgat
    10861 acgtaaagat ttagaggcta tggcagcaga tggggtgtct tggcttgtgt ttacaggaag
    10921 tttgggtttt gaatattggg ttttagaggt tgctcaggag atgaaaaccg aatacggttt
    10981 ccagttggcc accatttttg cttttgaaac ccatggggaa aattggaatg aaggcaatca
    11041 gatgaaactg agtcgcttta agcaggtaga ctttgtcaaa tatgcttatc ctcgctatga
    11101 acacaagggg cagttaagag attaccagca gtttttgctg gaaaacacga ctagttccta
    11161 tcttttttat gatgaagaaa atgaaacaaa actagcttat ttttaccaaa agatgaaaaa
    11221 tcaagaggac tattttataa agagattaac atttgatcaa ttaaatgaac ttgctgaaaa
    11281 tttttccgaa aattgaagct ttgaccttga tttttgtttg ccttttttta tataataata
    11341 ctagcaagcg agaatggaga gagacatggc aagtattatt ttttcagcga aagatatttt
    11401 tgaacaagag tttggacgtg aagtccgtgg ctataataaa gtagaagttg acgagttttt
    11461 agacgatgtc atcaaggact atgaaaccta tgctgccttg gtcaagtcac ttcgtcagga
    11521 aattgcggat ttgaaggaag aattaactcg taaaccgaaa ccttcaccag ttcaagcaga
    11581 accccttgaa gcggcaatta caagttctat gacgaatttt gatattttga aacgcctgaa
    11641 tagattggaa aaagaagttt ttggtaaaca aattttagat aactcagatt tttaagtagt
    11701 tatttgagat gtgcaatttt tggataatcg cgtgaggaga attgcttctc atgaggaaag
    11761 tccatgctag cacaggctgt gatgcctgta gtgtttgtgc taggcgaaac cataagccta
    11821 gggacgagga atcgttacgg cagttgaaat ggctaagtcc ttggataggc cagagtaggc
    11881 ttgaaagtgc cacagtgacg aagtctttct ggaaacagag agagtggaac gcggtaaacc
    11941 cctcaagcta gcaacccaaa ttttggtcgg ggcatggagt acgcggaaac gaacgtagta
    12001 ttctgactgc tatcagctag agctgttagt ggtagacaga tgattatcga aggaagtggt
    12061 cctagtcact tctggaacaa aacatggctt atagaaaatt gcatataggt tggggctgag
    12121 aaattttctc aacctcattt tttaaagtgg acatatagaa aggtcttgca agactgtaac
    12181 atgaaaaaag aatttaattt aattgcaact gcggcagcag ggcttgaggc tgtcgttggt
    12241 cgtgaagtgc gagagttggg ctacgattgt cagattgaaa atggacgtgt tcgttttcaa
    12301 ggagacgtga gagctattat cgaaaccaac ctttggctgc gggcagcaga tcgtatcaaa
    12361 attatcgtag gaacgttccc tgctaagact tttgaagagc tatttcaggg agttttcgct
    12421 ttagattggg aaaattattt accacttgga gctcggttcc cgatttcaaa agctaaatgt
    12481 gttaagtcca aacttcacaa tgagcccagt gttcaggcta tttctaagaa agctgttgtc
    12541 aagaaattgc agaaacacta tgctcgccca gaaggggttc ctctgatgga gaatggccca
    12601 gagtttaaga ttgaggtctc tattctcaaa gatgtggcaa ctgtcatgat tgatacgacc
    12661 gggtctagcc tctttaaacg tggttatcgt accgaaaaag gtggcgctcc tatcaaggaa
    12721 aatatggcag cagccatttt acaactttct aactggtatc cagacaagcc tttgattgat
    12781 ccgacctgtg gttcggggac tttctgtatt gaggcagtta tgattgctag aaagatggcg
    12841 ccaggtcttc gtcgctcttt tgcatttgag gaatggaact ggatcagcga tcgcttgatt
    12901 caagaagtgc gcacagaagc ggctaaaaaa gtagaccgtg agcttgagct ggatatcatg
    12961 ggctgtgata ttgatgctcg catggtggaa attgctaagg ccaatgctca ggcagctggt
    13021 gttgcaggag acattacttt taagcagatg cgcgtgcagg atttacgttc cgataaaatc
    13081 aatggagtaa tcatttccaa tccgccttat ggtgaacgtt tgtcagatga tgcaggggtg
    13141 accaagctct atgctgagat ggggcaagta tttgcaccgc tgaaaacttg gagcaaattt
    13201 atcctgacta gtgatgaagc ttttgaaagc aagtatggta gccaagcaga taagaagcgt
    13261 aagttataca acggaacctt gaaagtggat ctgtatcaat attttggtca gcgtgtcaaa
    13321 cggcaagagg taaaatagaa agggatactc atgagtaaaa aaagacgaaa tcgtcaaaaa
    13381 aaagaaggtc aagaaccgca atttgatttt gatgaagcaa aagagctaac agttggtcaa
    13441 gctattcgta aaaatgaaga agtggaagca ggagtcttgc ctgaggattc cattttggac
    13501 aagtatgtta agcaacacag agatgaaatt gaggcggata agtttgcgac tcgtcaatac
    13561 aaaaaagagg agttcgttga aactcagagt ctggatgatt taattcaaga gatgcgtgag
    13621 gctgtagaga agtcagaagc ttcttcggag gaagttccat cttctgaaga catcttacta
    13681 cccttgcctc tggacgatga ggagcaaggc ttggatcctc tattgctaga tgatgaaaat
    13741 ccaacagaaa tgactgaaga agtggaagag gagcaaaacc tttctcgtct ggatcaagag
    13801 gactcagaaa agaaaagtaa aaaaggcttt attttgaccg ttttggcgct tgtatcagta
    13861 attatttgtg tcagtgctta ttatgtctac cgtcaagtgg ctcgttcgac caaggaaatt
    13921 gaaacttctc aatcaactac agccaatcaa tcggatgtgg atgattttaa tacactttat
    13981 gacgcctttt acacagatag caataaaacg gctttgaaaa atagccagtt tgataaactg
    14041 aatcaactca agactttact tgataagctg gaaggtagtc gtgaacatac gcttgccaaa
    14101 tctaaatatg atagtctagt aacgcaaatc aaggctattc aagatgtcaa tgctcaattt
    14161 gagaaaccag ctattgtgga tggtgtgttg gatgccaatg ccaaagccaa atcggatgct
    14221 aaatttacgg atattaaaac tggaaatacg gagcttgata aagtgctaga taaggctatc
    14281 agtcttggta agagccagca aacaagtact tctagctcaa gttcaagtca agcaagctca
    14341 aatacgacaa gtgagccaaa accaagtagt tcaaatgaga ctagaagtag tcgcagtgaa
    14401 gtcaatatgg gtctctcgag tgaaggggtt gctgttcaaa gaagtgccag tcgtgttgcc
    14461 tataatcagt ctgctattga tgatagtaat aactctgcct gggattttgc ggatggtgtc
    14521 ttggaacaaa ttctagcgac ttcacgttca cgtggctata tcactggaga ccaatatatc
    14581 cttgaacgtg tcaatatcgt taacggcaat ggttattaca acctctataa gccagatgga
    14641 acctatctct ttacccttaa ctgtaagaca ggctactttg tcggaaatgg cgctggtcat
    14701 gcagatgact tggactacta agcagtcgtt acaaaattct ttcttttcaa aagtaaaaat
    14761 gataaaataa aacaaatgaa acaagaggag tgtcaaatga caaaagctaa ctttggtgtc
    14821 gtaggtatgg ccgtaatggg tcgtaacctt gcccttaata ttgaatcacg tggttacaca
    14881 gttgctatct acaaccgtag taaagaaaaa acggaagatg tgattgcttg ccatcctgaa
    14941 aagaattttg taccaagcta tgacgttgaa agttttgtaa actcaatcga aaaacctcgt
    15001 cgtatcatgc tgatggttca agctggacct ggtacagatg ctactatcca agcccttctt
    15061 ccacaccttg acaagggtga tatcttgatt gacggaggaa acactttcta caaagatacc
    15121 atccgtcgta atgaagaatt ggcaaactca ggtatcaact ttatcggtac tggagtttct
    15181 ggtggtgaaa aaggtgccct tgaaggtcct tctatcatgc ctggtggaca aaaagaggcc
    15241 tacgaattgg tttcggatgt tcttgaagaa atctcagcta aagcaccaga agatggcaaa
    15301 ccatgtgtga cttatatcgg tcctgatgga gctggtcact atgtgaaaat ggttcacaac
    15361 ggtatcgagt acggtgatat gcaattgatc gcagaaagct atgacttgat gcaacacttg
    15421 ctaggccttt ctgcagagga tatggctgaa atctttactg agtggaacaa gggtgaattg
    15481 gatagctact tgatcgaaat cacagctgat atcttgagcc gtaaagacga tgaagaccaa
    15541 gatggaccaa tcgtagacta catccttgat gctgcaggta acaagggaac tggtaaatgg
    15601 acgagccaat catctcttga ccttggtgta ccattgtcac tgattactga gtcagtgttt
    15661 gcacgctaca tttcaactta caaagaagaa cgtgtacatg ctagcaaggt gcttccaaaa
    15721 ccagctgcct tcaactttga aggagacaag gctgaattga ttgaaaaaat ccgtcaagcc
    15781 ctttacttct caaaaatcat ttcatacgca caaggatttg ctcaattgcg tgtagcctct
    15841 aaagaaaaca actggaactt gccatttgca gatatcgcat ctatctggcg tgatggctgt
    15901 atcatccgtt ctcgtttctt gcaaaagatt acagatgctt acaaccgcga tgcagatctt
    15961 gccaaccttc ttttggacga gtacttcttg gatgttactg ctaagtatca acaagcagtg
    16021 cgtgatatcg tagctcttgc ggttcaagct ggtgtgccag tgccaacttt ctcagcagct
    16081 attacttact ttgatagcta ccgttcagct gaccttccgg ctaacttgat ccaagcacaa
    16141 cgtgactact ttggtgctca cacttaccaa cgtaaagaca aagaaggaac cttccactac
    16201 tcttggtatg acgaaaaata agtaggtcag ccatggggaa acggatttta ttacttgaga
    16261 aagaacgaaa tctagctcat tttttaagtt tggaactcca gaaagagcag tatcgggttg
    16321 atctggtaga ggaggggcaa aaagcccttt ccatggctct tcagacagac tatgatttga
    16381 ttttattgaa cgttaatctg ggagatatga tggctcagga ttttgcagaa aaattgagtc
    16441 gaactaaacc tgcctcagtc atcatgattt tagatcattg ggaagacttg caagaagagc
    16501 tggaagttgt tcagcgtttt gcagtttcat acatctataa gccagtcttt atcgaaaatc
    16561 tggtagcgcg tatttcggcg atcttccgag gtcgggactt cattgatcaa cactgcagtc
    16621 tgatgaaagt tccaaggacc taccgcaatc ttaggataga tgttgaacat cacacggttt
    16681 atcgtggtga agagatgatt gctctgaccc gccgtgagta tgaccttttg gcgacactta
    16741 tgggaagcaa gaaagtattg actcgtgagc aactgttgga aagtgtttgg aagtatgaaa
    16801 gtgcgaccga gacaaatatc gtagatgtct atatccgcta tctacggagc aagcttgatg
    16861 ttaaaggtca aaaaagctac attaaaaccg tgcgtggtgt tggttacacc atgcaagaat
    16921 agaaaagcag ttgcagttgt gtaactgctt ttttgaggag tttttatata ttgacatgca
    16981 gtcgggtctt tgctacaatc gttttaggag gatatataga tgaaactttt gaaaaaaatg
    17041 atgcaagttc tactagcagt ctttttcttt ggtttgctag ctacaaatac ggtatttgcg
    17101 aataccacag gtggccgatt tgttgataag gataatagaa aatattatgt aaaagatgat
    17161 cataaagcaa tctattggca taaaatagac ggtaaaactt actattttgg tgatattgga
    17221 gagatggttg tcggttggca atacttagaa attcctggaa caggttatcg tgataattta
    17281 ttcgataacc aaccagttaa tgaaattggc cttcaggaga agtggtacta ttttggacaa
    17341 gatggtgctt tgctagaaca aacagataaa caagtactag aggcaaaaac gtctgaaaat
    17401 acaggaaaag tatacggtga acaatatcct ctatctgctg aaaagagaac ttattatttt
    17461 gataataatt atgctgtaaa gacaggctgg atttatgaag acggcaattg gtattattta
    17521 aataagctag gaaattttgg cgatgattct tacaatccac taccaattgg tgaagttgct
    17581 aagggttgga ctcaagattt tcatgttact attgacattg atagaagcaa acttgctcca
    17641 tggtactacc tagacccaga aactggcatt atgcgaacag gatggcaata tctaggtaat
    17701 aactggtact acctccgttc atcaggagca atggcaacag gttggaaata tgtacgaggc
    17761 aaatggtatt acttagataa taaaaatggt gatatgaaga ctggttggta tcaagatggt
    17821 tcaacttggt actatttaga tccttctaat ggagatatga aaataggttg gacaaaagta
    17881 aatggaaaat ggtattatct caattcaaat ggagcaatgg ttacaggtag tcaaactatc
    17941 gatggtaaag tttataactt cgcttcatct ggtgagtgga tttaatgttg gaggatatat
    18001 aaaatgaagc ttttgaaaaa aactatgcaa gctggactaa cagtaatttt ctttggtttg
    18061 ctagctacga atacagtatt tgcagataac tctgaaggat ggcagtttgt ccaagaaaac
    18121 ggtagaacct attacaaaaa gggggacctc aaagaaacct actggcgagt gattgatggt
    18181 aagtactatt attttgattc tctatctgga gagatggttg tcggctggca atatatcccg
    18241 tttccatcta aaggtagtac aattggtcct tacccaaatg gtatcagatt agaaggtttt
    18301 ccaaagtcag agtggtacta ctttgataaa aatggagtgc tacaagagtt tgttggttgg
    18361 aaagaattag agattaaaac tcaagacagt gttggaagaa agtatgggga aaaacgtgaa
    18421 aattcagaag ataaagaaga gaagcgttat tacacgaact attactttaa tcaaaatcat
    18481 tctttagaga caggttggct ttatgatcag tctaactggt attatctagc taaaacagaa
    18541 attaatggag aaaactatat tggtggtgaa agacgtgcag gttggataaa tgatgcttca
    18601 gcttggtact acctagatcc agcaactggt attatgcaaa caggttggca atatctaggt
    18661 aataagtggt actacctccg ttcctcagga gcaatggcca ctggctggta tcaggaaggt
    18721 accacttggt attatttaga ccacccaaat ggcgatatga aaacaggttg gcaaaacctt
    18781 gggaacaaat ggtactatct ccgttcctca ggagctatgg caactggttg gtatcaagat
    18841 ggttcaactt ggtactacct aaatgcaggt aatggagaca tgaagacagg ttggttccag
    18901 gtcaatggca actggtacta tgcttatagc tcaggtgctt tggcagtgaa tatgaccgta
    18961 gatggctatt ctgtcaacta taatggcgaa tgggttcggt aatgacaggg cgcttataat
    19021 tatattagaa cactcgctta atcaaagaag tgactttgtt gtacttgacc tgacgattgg
    19081 ggagattaaa agcatgtgaa atctacacat gctttttcgt tagttatgag tgttgaactt
    19141 gactaaccat tgacaaaaga taagagcaat caaaataaga tacaaaaata tcaatgctaa
    19201 ctgcaccgaa acgcccgatg ctatggatag ggctaatagg gagagcaggg acggggcgag
    19261 aatgtctact gtgctcagag cagagcccac cgtccccatc ttgtcactgg ggatatgggc
    19321 aaagacagct gcttgtaggc gagggctgag aatgccgata atcgtagaac tgatgaaact
    19381 ggtcacgaaa attacgatat aggcttgaca aaggatacta gttattagag ccaataggga
    19441 aatctcacag aaaaccaaga ggtgcgtgaa acggatattt ttaaatagat tactgctggt
    19501 catattgcca aggatagctc cacaagacat gatgatggag agcagggaga agagttgccc
    19561 aatgctcagt tgtgctagtg tctgttggat gaagcggagg gcaatcagcc gaggggacac
    19621 atccaagatg gcaatcatac tggtcgtcag aaacagtagt atgacggtat cttttaacct
    19681 caggagcaca gccagcgact gtttaagatg ttgaaaatat ttcttaaaac tcagtgctgt
    19741 atgtgacatt tcaatccttt tttcaacctc atacaaggta tgtcgaataa catacaggcc
    19801 caaaaaggca atgacaaaag tcagagtgtt gataagggaa atagtttgaa tactcataac
    19861 attgataagg aatgcgccag ctagattggc gacaatgcgg acaaccctca tcagagactg
    19921 cctgaacccc atggcatcat gcaggtcgtc cttaattaca ctgatgtaga gggcgttcat
    19981 catgtaggca gacaggtagc tcaaggtgtc agagatgagg ttgatgatga caatcataat
    20041 gactgaaact aatgaaaagg gcgacaagac gagaaatact gtcaaaatag cgtagagcag
    20101 gattttgatt ttggcaatcc agagtgcgtg tttgactcta ttttcttgaa aatctcctag
    20161 aattccgaga aagagttgcg atagtagggg aaccacctct gaaatggaaa tcagtaaaat
    20221 cgctagcgga gcgaaattgt actgagccac ataattgata atggcaaggt agaaaatact
    20281 gtcgccgaat gatgaaaaac agctgtttag caacaactgt ctatatatgt tgtttgtcca
    20341 aaataatttc atacatttct ccttatgtct gcacatcgaa tgggaattta ttatttaata
    20401 gacaccaata tacccccatg cttcctattc cgaagtcaaa caaatctgct ttaccactat
    20461 ctccttgaaa catcagtaaa ccgtgatcat ctcgttcaga acatgctaaa attacctgtt
    20521 ggattttttt catcagtaat ttgttttgat tgtagacagt ggtttgtagt aagctagtta
    20581 ttccgtggca atatcctgtc atcattttta gatgatggtt aaaaacaaat tcttgatatt
    20641 tactaataat atctttgttt ccgtcacaat cgtacataca aagatataag attattccgg
    20701 aaattccttt gcaccaagaa agttgtaaat ttcctaaatt ttcagtatta gaagtaactt
    20761 tttctaataa tttttttaat tcagtatgga atgtatggag atcattatag aacatagaag
    20821 gttctaagac tttagaatag gcaaataaag cctatgcaat tccacaatat ccatgagcaa
    20881 agctatagtc taaaatgctt tctttggcta tatctctttg taggaaataa tgctaaattt
    20941 cccctatact attgtggatg aaaattttaa gagtattgtc attggtaaat tgatagtatt
    21001 ttattaatga taataggaca ccagattttc ccaatgcaaa gtctatttcc tctagagtat
    21061 cataattctc tattaatttc ttagcggtga cgtttgctaa ttgtagatag tattgatttt
    21121 tactgataga aaataaatgt aggagtaacc atagataacc tgcatcacca aatagcagtg
    21181 agtattgata ttcatatgtg tgtgtcgttc taattgtcac tgccttcttg atgatagaga
    21241 gtattttaga atccagttct gggtggtaca atttatttag aggaaacagt agtccagcta
    21301 ttccgtgttg gaatgataaa ttacttacga aatttccaaa ttctgttgaa gaagtgatcc
    21361 ttccttcaga atttacagtt ttatctagta aaaatcgtag aacactgtta cattctgttt
    21421 tgtaatcata tttatgttcc tctatttttt taattttgac taaattattt gtttgactta
    21481 aatttagtag acattgtaac caaaatagtt gctcatctgt gagctgacct tgagtatgtg
    21541 atagttctag taattgaata ggatccttta gttagattca atcaatctat aacacaacaa
    21601 cataataata cttttaggat aacttatcaa atattatagt aaaatgagat aataacagga
    21661 taaatcgatc aggacagtca aatcgatttc taacaatatt ttagaagtag aggtgtacta
    21721 ttctagtttc aatctactat agtatatatt tttacatctt gaattgtcaa attaagtgca
    21781 taactttccc gtagcatact tcataaggcg ttttccactt aagaaatttt cgtggtcgat
    21841 tatttagaac ctgtattcac aaaaaatgtt aaactagagt tatgacacgc aaagtatatg
    21901 atactgattt aaacgatcaa gaatgggcta agattgaacc ctatttctcc aaacaccgca
    21961 cctataaatg gccgaaacga gtacttgtta atgagacttt gtacgtcact aaaacaggtt
    22021 gtcaatggcg catgctccct cacgactttc ctctttactt aatggtatgg agtttctttc
    22081 gtcgttctat gacgacaggt tggttccagg tcaatggcag atggtactac gcttatagct
    22141 caggtgcctt ggcagtgaat acgaccgtag atggctattc tgtcaactat aatggcgaat
    22201 gggttcaata atgaaagaag cgattgtgaa tggaaacaat cgcttttttt gtgaaaatat
    22261 aataaaatag ataggaaaga attaatactt gtatgaaaaa taagacgttt tttcgtctag
    22321 taaaaggaaa aaatgacaaa aaaagttggt gtcggtcagg cacatagtaa gataatttta
    22381 ataggggaac atgcggtcgt ttacggttat cctgccattt ccctgcctct tttggaggtg
    22441 gaggtgacct gtaaggtagt tcctgcagag agtccttggc gcctttatga ggaggatacc
    22501 ttgtccatgg cggtttatgc ctcactggag tatttgaata tcacagaagc ctgcattcgt
    22561 tgtgagattg actcggctat ccctgagaaa cgggggatgg gttcgtcagc ggctatcagc
    22621 atagcggcca ttcgtgcagt atttgactac tatcaggctg atctgcctca tgatgtacta
    22681 gaaatcttgg tcaatcgagc tgaaatgatt gcccatatga atcctagtgg tttggatgct
    22741 aagacctgtc ttagtgacca acctattcgc tttatcaaga acgtaggatt tacagaactt
    22801 gagatggatt tatccgccta tttggtgatt gccgatacgg gtgtttatgg tcatactcgt
    22861 gaagccatcc aagtggttca aaataagggc aaggatgccc taccgttttt gcatgccttg
    22921 ggagaattaa cccagcaagc agaagttgcg atttcacaaa aagatgctga aggactggga
    22981 caaatcctca gtcaagcgca tttacattta aaagaaattg gagtcagtag ccctgaggca
    23041 gactttttgg ttgaaacgac tcttagccat ggtgctctgg gtgccaagat gagcggtggt
    23101 gggctaggag gttgtatcat agccttggta accaatttga cacacgcaca agaactagca
    23161 gaaagattag aagagaaagg agctgttcag acatggatag agagcctgta acagtacgtt
    23221 cctacgcaaa tattgctatt atcaaatatt ggggaaagaa aaaagaaaaa gaggtggtgc
    23281 ctgctactag cagtatttct ctaactttgg aaaatatgta tacagagacg accttgtcgc
    23341 ctttaccagc caatgtaaca gctgacgaat tttacatcaa tggtcagcta caaaatgagg
    23401 tcgagcatgc caagatgagt aagattattg accgttatcg tccagctggt gagggctttg
    23461 tccgtatcga tactcaaaac aatatgccta cggcagcggg tctgtcctca agttctagtg
    23521 gtttgtccgc cctggtcaag gcttgtaatg cttatttcaa gcttggattg gatagaagtc
    23581 agttggcaca ggaagccaaa tttgcctcag gttcttcttc tcggagtttt tatggaccac
    23641 taggagcctg ggataaggat agtggagaaa tttaccctgt agagacagac ttgaaactag
    23701 ctatgattat gttggtgcta gaggacaaga aaaaaccaat ctctagccgt gacgggatga
    23761 aactttgtgt ggaaacctcg acgacttttg acgactgggt tcgtcagtct gagaaggact
    23821 atcaggatat gctgatttat ctcaaggaaa atgattttgc caagattgga gaattaacgg
    23881 agaaaaatgc cctggctatg catgctacga caaagactgc tagtccagcc ttttcttatc
    23941 tgacggatgc ctcttatgag gctatggact ttgttcgcca gcttcgtgag aaaggagagg
    24001 cctgctactt taccatggat gctggtccca atgttaaggt cttctgtcag gagaaagact
    24061 tggagcattt atcagaaatt ttcggtcatc gttatcgctt gattgtgtca aaaacaaagg
    24121 atttgagtca agatgattgc tgttaaaact tgcggaaaac tctattgggc aggtgaatat
    24181 gctattttag agccagggca gttagctttg ataaaggata ttcccatcta tatgagggct
    24241 gagattgctt tttctgacag ctaccgtatc tattcagata tgtttgattt cgcagtggac
    24301 ttaaggccta atcctgacta cagcttgatt caagaaacga ttgctttgat gggagacttc
    24361 ctcgctgttc gcggtcagaa tttaagacct ttttccctaa aaatctgtgg caaaatggaa
    24421 cgagaaggga aaaagtttgg tctaggttct agtggcagcg tcgttgtctt ggttgtcaag
    24481 gctttattgg ctctctataa tctttcggtt gatcagaatc tcttgttcaa gctgactagc
    24541 gctgtcttgc tcaagcgagg agacaatggt tccatgggcg accttgcctg tattgtggca
    24601 gaggatttgg ttctctacca gtcatttgat cgccagaagg cggctgcttg gttagaagaa
    24661 gaaaacttgg cgacagttct ggagcgtgat tggggatttt ttatctcaca agtgaaacca
    24721 actttagaat gtgatttctt agtgggatgg accaaggaag tggctgtatc gagtcacatg
    24781 gtccagcaaa tcaagcaaaa tatcaatcaa aattttttaa gttcctcaaa agaaacggtg
    24841 gtttctttgg tcgaagcctt ggagcagggg aaagccgaaa aagttatcga gcaagtagaa
    24901 gtagccagca agcttttaga aggcttgagt acagatattt acacgccttt gcttagacag
    24961 ttgaaagaag ccagtcaaga tttgcaggcc gttgccaaga gtagtggtgc tggtggtggt
    25021 gactgtggca tcgccctgag ttttgatgcg caatcaacca aaaccttaaa aaatcgttgg
    25081 gccgatctgg ggattgagct cttatatcaa gaaaggatag gacatgacga caaatcgtaa
    25141 ggacgagcat attctctatg cccttgagca gaaaagttcc tataatagct ttgatgaggt
    25201 ggagctgatt cattcttcct tgcctcttta caatctggat gaaatcgatc tttcgacaga
    25261 gtttgctggt cgaaagtggg actttccttt ttatatcaat gccatgactg gtggaagtaa
    25321 taagggaaga gaaatcaatc aaaagctggc tcaggtggcg gaatcctgtg gtattttatt
    25381 tgtaacgggt tcttatagcg cagccctcaa aaatccaacg gatgattctt tttctgtcaa
    25441 gtctagtcat cccaatctcc tccttggaac caatattgga ttggacaagc ctgtcgagtt
    25501 aggacttcag actgtagaag agatgaatcc tgtgctattg caagtgcatg tcaatgtcat
    25561 gcaggaatta ctcatgcccg agggagaaag gaagtttaga agctggcaat cgcatctagc
    25621 agattatagc aagcaaattc ccgttcctat tgtcctcaag gaagtgggct ttggaatgga
    25681 tgccaagaca atcgaaagag cctatgaatt cggtgttcgt acagtggacc tatcgggtcg
    25741 tggtggcacc agctttgcct atatcgaaaa ccgtcgtagt agccagcgtg attacctcaa
    25801 tcaatggggt cagtctacca tgcaggccct tctcaatgcc caagaatgga aagataaggt
    25861 cgaactcttg gttagtggag gggttcggaa tccgctggat atgattaagt gcttggtttt
    25921 tggtgctaag gctgtgggat tgtcacgaac cgttctggaa ttggttgaaa cctacacagt
    25981 tgaagaagtg attggcattg tccaaggctg gaaagcagat ctacgcttga ttatgtgttc
    26041 ccttaactgt gccaccatag cagatctaca aaaagtagac tatcttcttt atggaaaatt
    26101 aaaagaagca aatgatcaga tgaaaaaggc gtaaccagcg cctttttttc catcctcaga
    26161 ctgaggtgac ttttttgaat tgtgataaaa tagaagggag aggatgaacc tatgagaaaa
    26221 tttaaaatct ttttatttat cgaagcctgt cttctgacag gagctctgat tttgatggta
    26281 tcagagcatt tttcgcgttt tctgctgata ctattcctct ttttgctttt gattcgctac
    26341 tacactggta aagagggaaa taatcttctt ttagtagcgg taaccattct cttctttttc
    26401 atcgttatgc tcaatccttt tgtgattcta gctatttttg ttgcggttat ctatagcctc
    26461 tttcttcttt acccgatgat gaaccaggaa aaagagcaga ccaatttggt ttttgaagag
    26521 gttgtgacgg ttaagaagga gaaaaatcgt tggtttggaa atcttcatca tttttcaagc
    26581 taccagactt gccaattcga tgatatcaat ctctttcgct tcatgggcaa ggacactatt
    26641 catctggaga gggtcatctt aaccaatcat gacaatgtca ttatcctcag aaagatggta
    26701 ggaacgacca aaatcatcgt acctgtagat gtggaagtca gtctcagcgt taactgtctc
    26761 tatggggatt tgactttttt caaccagccc aagcgagccc tccgcaatga acactatcat
    26821 caagaaacaa aagactatct caagagtaac aagagtgtca agattttctt gaccactatg
    26881 attggtgatg tggaggtggt tagaggatga aaaaacaagc ctatgtcatt attgctctca
    26941 cctccttcct atttgtcttt tttttctccc acagcttgct ggaaatactt gattttgact
    27001 ggtctatctt tttgcacgat gtcgaaaaaa cagaaaaatt tgtcttttta ttgttggttt
    27061 tcagcatgtc catgacctgt ctcttagccc tgttttggcg agggatcgaa gagctttctc
    27121 taagaaaaat gcaggctaat ctcaagcgtt tattggcagg gcaagaagta gttcaggttg
    27181 tagatcaaga tttggatgcc agtttcaagt ccttatcagg taaacttaac cttttgacag
    27241 aggctcttca aaaagctgaa aatcatagcc ttgctcagga agaggaaatc atcgagaagg
    27301 aacggaagcg aattgctcgg gatttgcacg atacagtcag tcaggagttg tttgcggccc
    27361 acatgatttt atcgggtatc agtcagcagg ctttgaaatt ggatagagaa aagatgcaga
    27421 cccagttgca gagtgtcaca gctattttag aaacagccca gaaggatttg cgggttttgc
    27481 tcttgcattt gcgaccagtt gaactggagc agaagagctt gatagaaggg attcaaattc
    27541 tcttaaaaga gcttgaggac aagagtgatc ttagggttag tctcaagcag aatatgacga
    27601 aattgcctaa gaaaatcgag gagcatatct tccgtatcct gcaagagttg attagcaata
    27661 cgctccgcca tgcccaggca tcttgcctag atgtctacct ctatcagaca gatgttgaat
    27721 tgcaactgaa ggtggtggac aatgggattg gtttccagtt agggagctta gacgacttga
    27781 gttatggact gcgaaatatc aaggagcggg ttgaagatat ggcagggacg gttcagttat
    27841 taacagctcc caagcaaggg ctggcagttg atatccgtat tcccctgtta gataaggaat
    27901 gataaaggag taaagatgaa aattttacta gtagatgacc atgaaatggt ccgtttgggt
    27961 ttgaaaagct actttgacct ccaagacgat gtagaagttg tgggtgaggc gtccaacggg
    28021 tctcaaggga ttgacttggc cttggaactg cgtccagatg tcattgtcat ggatattgtc
    28081 atgcctgaga tgaatggaat tgacgcgacc ttagcaatcc ttaaagaatg gcctgaagcc
    28141 aagattttga ttgtgacctc ttatttggac aatgaaaaaa tcatgccagt cttagatgct
    28201 ggtgccaaag gctatatgct caagacttct agtgcagatg aattgcttca tgccgtcagt
    28261 aaggtagctg ctggcgagct ggccattgag caagaggtta gcaagaaggt tgaataccac
    28321 cgcaatcata tggaacttca tgaagaattg actgcgcgtg agcgagatgt tctccaactc
    28381 atcgccaagg gctacgaaaa tcagcgcatc gcagatgacc tctttatctc tctcaagacg
    28441 gtcaagaccc acgtgtccaa cattcttgcc aaacttgaag tcagcgatcg tacccaggcg
    28501 gctgtctacg cctttcagca ccatttggtg gggcatgagg agttttagat gagtttagca
    28561 gatttacttt aggagctaga agcagcaaaa gactctaaaa agcaaggccc atggaagcct
    28621 atatgcgcca tcaattttct tttctaggta ttgcggtgcc tgaaagaaat aaactctata
    28681 aaaatattta ccagaagcga aaaaaacaaa gattatcgat tgggattttg cagacacttg
    28741 ctgggaaaag gagcctagaa aataccaata tgtggctgct aactatttga aagcaatgca
    28801 gtcttatcta aaggaaaccg atttgcctaa gctagagcag ttagtcgtga caaaatcctg
    28861 gtgggacacg gtagatatcc tagatcgagt agtagggagt ttggtgtatg aacaccctga
    28921 actagaagaa ataatcttaa tactcttcga aaatctcttc aaaccacgtc agctctatct
    28981 gcaacctcaa aacagtgttt tgagcaacct gcagctagct tcctagtttg ctctttgatt
    29041 ttcattgagt ataaaatgga gcctatcaga taatatctgg ctgagacgtg tcgctattga
    29101 ccaccagttg ttaataaaag agaagaccaa tactcaatta atggaaaaga ttctacttca
    29161 taacttgaac caaacagaat tttttatcaa taaagccatt ggctggactc tgcgagacta
    29221 ctccaaaacg aatcccactt gggtaacatg ctttattgag aaaaacaagg aaagaatggc
    29281 tgaacttagt atcaaagaag caagtaagta cctctagcgt gattgaaaag cgcagtcatt
    29341 aattgaaaag tttacctgtt tatgtgataa tggagggtat ttaaagaagg tggtagattt
    29401 cttgattcta tagtagatta agaaatttag aatagtacgc tataattaca ttaggaggat
    29461 acaataatga agaaaactgt ttataaaaaa ttgggtattt caattattgc gagtacttta
    29521 ttggctagcc agttatcgac agtatctgct ttgagtgtta tttctagtac aggtgaagaa
    29581 tatgaggtaa gtgagacact agaaaaaggt ccagagtcta atgattcttc attatctgag
    29641 atttcaccaa cgtatggttc atactaccaa aagcaatcag aagtattatc ggtaatgatg
    29701 atttgattaa aattgataat actttacagt atccgtattc gacttcagct atggttttat
    29761 ctaagtatta tggagtagcc gatggaatga atgtagaagg gaggggaagt gcgaatttta
    29821 ttaaagataa tgtgttaatt acagcggctc acaactacta cagacatgac tatgggaaag
    29881 aagcggatga tatttatgtt cttccggctg ttagtccaag tcaagaacta tttggaaaga
    29941 tcaaagtaaa ggaagttcgt tatttgaagg aatttagaaa tttaaattct aagaatgcaa
    30001 gggaatatga cttggcttta ttaattctag aagagcccat tggtgcaaaa ttagggactt
    30061 tgggtcttcc tactagtcaa aaaaatttga caggaataac tgtgactatc acaggctatc
    30121 tatcatataa ttttaaaatt catcaaatgt atacagataa aaaacaagtt ttaagtgatg
    30181 atggcatgtt cttggattac caagttgata ctttagaggg gtctagtgga tctgcagttt
    30241 atgatgctag tcaccgcgta gtaggagtgc atactttagg agatggagct aatcaaatta
    30301 acagtgcagt taaattaaat gaacgaaatt tgccatttat ttattcggtt cttaaaggtt
    30361 actctcttga aggatggaag aaaataaatg gtagttggta ctattataga caacatgata
    30421 aacaaacggg ttggcaggag ataaatgata cttggtatta tttagacagt tccggtaaga
    30481 tgcttacaga ttggcaaaaa gtaaatggaa aatggtatta tctcaattca aatagagcaa
    30541 tggttacagg tagccaaact atcgatggta aagtttataa cttcgcttca tctggtgagt
    30601 ggatttaatg ttggaggata tataaaatga agcttttgaa aaaaatgatg caagtcgtac
    30661 tagccacatt tttcttcggt ttgctaggga ccagtacagt atttgcagat gattctgtag
    30721 gatggcagtt tgtccaagaa aatggtagaa cctactacaa aaagggggat ctaaaagaaa
    30781 cctactggcg agtgattgat ggtaagtact attattttga tcctttatcc ggagagatgg
    30841 ttgtcggctg gcaatatata cctgctccac acaagggggt tacgattggt ccttctccaa
    30901 gaatagagat ttctcttaga ccagattggt tttattttgg tcaagatggt gtattacaag
    30961 aatttgttgg caagcaagtt ttagaagcaa aaactgctac gaataccaac aaacatcatg
    31021 gggaagaata tgatagccca gcagagaaac gagtctatta ttttgaagat cagcgtagtt
    31081 atcatacttt aaaaactggt tggatttatg aagagggtca ttggtattat ttacagaagg
    31141 atggtggctt tgattcgcgc atcaacagat tgacggtggg agagctagca cgtggttggg
    31201 ttaaggatta ccctcttacc tatgatgaag agaagctaaa agcagctcca tggtactacc
    31261 tagatccagc aactggcatt atgcaaacag gttggcaata tctaggtaat aagtggtact
    31321 acctccattc gtcaggagct atggcaactg gctggtataa ggaaggctca acttggtact
    31381 atctagatgc tgaaaatggt gatatgagaa ctggctggca aaaccttggg aacaaatggt
    31441 actatctccg ttcatcagga gctatggcaa ctggttggta tcaggaaggt tcgacttggt
    31501 actatctaaa tgcaagtaat ggagatatga aaacaggctg gttccaagtc aatggtaact
    31561 ggtactatgc ctatgattca ggtgctttag ctgttaatac cacagtaggt ggttactact
    31621 taaactataa tggtgaatgg gttaagtaat gaaggctaat tgtaaactgt gatggatact
    31681 taactttgta taataggtgg ataaaagtct tcacaatcaa aaaacgcata gtatcaaggt
    31741 ttttctgtac tgccccccaa aagttagaca aataatttat ccaaaggatt tagttctgta
    31801 ctgcacagga ctaagtcctt ttagttttac cttaattctc ttgttgttgt aataatcaat
    31861 atagtctata atggcttgtt ccaattgatt aagtgattta aatgttttct catagccata
    31921 aaacatttcc gatttcagaa tcccaaagaa ggactccacc atagtgcttc tctgtgaatg
    31981 cctgttccaa cattgttttt acttgttcta agttgggtga agttgaaaga ttataggcga
    32041 taatttcgct gttaaagcca tctaaaactg gtgataagta aagcttttga gtacttgctg
    32101 gaatggaaaa ttcagtcaca tctgtgtagc act
//
LOCUS       DBERXF010000024        31697 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.24, whole genome shotgun sequence.
ACCESSION   DBERXF010000024 DBERXF010000000
VERSION     DBERXF010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 31697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31697
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.24"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(7..1395)
                     /gene="mobQ"
                     /locus_tag="ACL8JK_001231"
                     /pseudo
     CDS             complement(7..1395)
                     /gene="mobQ"
                     /locus_tag="ACL8JK_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000785367.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
     gene            complement(1709..2026)
                     /locus_tag="ACL8JK_001232"
     CDS             complement(1709..2026)
                     /locus_tag="ACL8JK_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HGS1786117.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKD
                     EIT"
     gene            complement(2082..2507)
                     /locus_tag="ACL8JK_001233"
     CDS             complement(2082..2507)
                     /locus_tag="ACL8JK_001233"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1786118.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            complement(2560..2744)
                     /locus_tag="ACL8JK_001234"
                     /pseudo
     CDS             complement(2560..2744)
                     /locus_tag="ACL8JK_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612340.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(2895..3689)
                     /locus_tag="ACL8JK_001235"
     CDS             complement(2895..3689)
                     /locus_tag="ACL8JK_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1786119.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHINS"
     gene            complement(3689..4696)
                     /locus_tag="ACL8JK_001236"
     CDS             complement(3689..4696)
                     /locus_tag="ACL8JK_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HGS1786120.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(4696..5703)
                     /locus_tag="ACL8JK_001237"
     CDS             complement(4696..5703)
                     /locus_tag="ACL8JK_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGS1786121.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(5693..6718)
                     /locus_tag="ACL8JK_001238"
     CDS             complement(5693..6718)
                     /locus_tag="ACL8JK_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HGS1786122.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(7111..7329)
                     /locus_tag="ACL8JK_001239"
     CDS             complement(7111..7329)
                     /locus_tag="ACL8JK_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1786123.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(7575..7853)
                     /locus_tag="ACL8JK_001240"
     CDS             complement(7575..7853)
                     /locus_tag="ACL8JK_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786124.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVFELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(8067..9689)
                     /gene="rlmD"
                     /locus_tag="ACL8JK_001241"
     CDS             complement(8067..9689)
                     /gene="rlmD"
                     /locus_tag="ACL8JK_001241"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGS1786125.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIELREH
                     YNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(9763..10737)
                     /locus_tag="ACL8JK_001242"
     CDS             complement(9763..10737)
                     /locus_tag="ACL8JK_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HGS1786126.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(10811..11425)
                     /gene="pmp23"
                     /locus_tag="ACL8JK_001243"
     CDS             complement(10811..11425)
                     /gene="pmp23"
                     /locus_tag="ACL8JK_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HGS1786127.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     QDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNRTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(11425..12399)
                     /locus_tag="ACL8JK_001244"
     CDS             complement(11425..12399)
                     /locus_tag="ACL8JK_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGS1786128.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(12407..13663)
                     /gene="glyA"
                     /locus_tag="ACL8JK_001245"
     CDS             complement(12407..13663)
                     /gene="glyA"
                     /locus_tag="ACL8JK_001245"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGS1786129.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAALIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(13725..14156)
                     /locus_tag="ACL8JK_001246"
     CDS             complement(13725..14156)
                     /locus_tag="ACL8JK_001246"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1786130.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIC"
     gene            complement(14158..14757)
                     /locus_tag="ACL8JK_001247"
     CDS             complement(14158..14757)
                     /locus_tag="ACL8JK_001247"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGS1786131.1"
                     /translation="MDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(14744..15583)
                     /gene="prmC"
                     /locus_tag="ACL8JK_001248"
     CDS             complement(14744..15583)
                     /gene="prmC"
                     /locus_tag="ACL8JK_001248"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGS1786132.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPAWSVTAADVSQEALELASENASNQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(15583..16662)
                     /gene="prfA"
                     /locus_tag="ACL8JK_001249"
     CDS             complement(15583..16662)
                     /gene="prfA"
                     /locus_tag="ACL8JK_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGS1786133.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(16659..17249)
                     /locus_tag="ACL8JK_001250"
     CDS             complement(16659..17249)
                     /locus_tag="ACL8JK_001250"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGS1786134.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            17372..17554
                     /locus_tag="ACL8JK_001251"
     CDS             17372..17554
                     /locus_tag="ACL8JK_001251"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HGS1786135.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            17690..19063
                     /gene="mnmE"
                     /locus_tag="ACL8JK_001252"
     CDS             17690..19063
                     /gene="mnmE"
                     /locus_tag="ACL8JK_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGS1786136.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     SQVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(19110..20045)
                     /gene="dapA"
                     /locus_tag="ACL8JK_001253"
     CDS             complement(19110..20045)
                     /gene="dapA"
                     /locus_tag="ACL8JK_001253"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGS1786137.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(20101..21177)
                     /locus_tag="ACL8JK_001254"
     CDS             complement(20101..21177)
                     /locus_tag="ACL8JK_001254"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGS1786138.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(21520..21592)
                     /locus_tag="ACL8JK_001255"
     tRNA            complement(21520..21592)
                     /locus_tag="ACL8JK_001255"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21557..21559),aa:Thr,seq:ggt)
     gene            complement(21692..22201)
                     /locus_tag="ACL8JK_001256"
     CDS             complement(21692..22201)
                     /locus_tag="ACL8JK_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGS1786139.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(22199..22295)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            22324..22755
                     /locus_tag="ACL8JK_001257"
     CDS             22324..22755
                     /locus_tag="ACL8JK_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGS1786140.1"
                     /translation="MKIPIQKFFNNEILAYLFFGIVTTLVAILLRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            22837..23214
                     /gene="mscL"
                     /locus_tag="ACL8JK_001258"
     CDS             22837..23214
                     /gene="mscL"
                     /locus_tag="ACL8JK_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGS1786141.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(23256..24350)
                     /gene="hemH"
                     /locus_tag="ACL8JK_001259"
     CDS             complement(23256..24350)
                     /gene="hemH"
                     /locus_tag="ACL8JK_001259"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HGS1786142.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGMRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESQDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            24505..25728
                     /gene="pepT"
                     /locus_tag="ACL8JK_001260"
     CDS             24505..25728
                     /gene="pepT"
                     /locus_tag="ACL8JK_001260"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGS1786143.1"
                     /translation="MTYPNLLDHFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(25764..26417)
                     /locus_tag="ACL8JK_001261"
                     /pseudo
     CDS             complement(25764..26417)
                     /locus_tag="ACL8JK_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
     gene            26415..26579
                     /locus_tag="ACL8JK_001262"
                     /pseudo
     CDS             26415..26579
                     /locus_tag="ACL8JK_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(26656..27299)
                     /locus_tag="ACL8JK_001263"
                     /pseudo
     CDS             complement(26656..27299)
                     /locus_tag="ACL8JK_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672611.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27406..27966)
                     /locus_tag="ACL8JK_001264"
                     /pseudo
     CDS             complement(27406..27966)
                     /locus_tag="ACL8JK_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672571.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(28192..31311)
                     /gene="phtE"
                     /locus_tag="ACL8JK_001265"
     CDS             complement(28192..31311)
                     /gene="phtE"
                     /locus_tag="ACL8JK_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HGS1786144.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNKKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         9148 a         6235 c         5444 g        10870 t
ORIGIN      
        1 aagattttac attaaaagaa ttttttcttc attccacttt ttaggactta gtttttcctt
       61 atctgatagg agttttttta atttcccgct tactacttta tattggtcta tatctttctt
      121 atgtttgtta taaaatgctt cttttgtgaa tatatttttc ttttgatatt cttcataaac
      181 ttcttttttg gctttgtaga tttcatagta tagaattttc ttttctacat cttccatttc
      241 tttatggatt gtctttgctt ttttatttag cctataacta ttagacttta aagtttctat
      301 ttttgtttgt aactgaccta tggtttctat gttgtttttt cttaaataac tatatgcact
      361 tgttagcttt ttgaagtcat atttttcttt attagttttt gcatatcctt ttagatattt
      421 acttttttct ttttgaattt ctgaataagt taatagataa tttgttagat taaaaagttt
      481 agggttgtct attaccttat ctctttcgat atccttaaat ttttcataag cagtagataa
      541 gttatctaat aaatttccta tccaaccctt taatgttttt atctcttctt ttattgtttt
      601 tacaagttga ttatattttc ttatttctct attatagttt cccttgtcag tttctattcc
      661 ctttctttcc attgcacttg ctgctgatcc taaatggatt gtcggtagat aatctgaatt
      721 ttatctttta aaactcctat ggtctactct tttttctgct cctgctcttt ctaaatattt
      781 gttacaaaga tctgaaaaat tttctctcca tttttctaca ttgcctgtat cgttccaggt
      841 tgttagttct acttttcttg tctttggttt tccatttttg tttaatactt tttctccttt
      901 ttcatctagg atatattctt tttttgactt ggctaagaac tctccttttt cgtttattgg
      961 tcgcattatg gtcattatat gacaatggat atttccattt ttatcttgac tctcatcatg
     1021 aattgcataa tctactatca ttccttgtga tgttaaattt tcttttatat atctttcaac
     1081 caggttttta ttttcactta aagataactc ttttggtagt cctattatga attgtcttgc
     1141 tagttgtgca ttagaatttt tttctgccat ttctacttta ttccataaga tagacctatc
     1201 attaaattct tttggtatat gatcaggcaa tattatattt tttactaata ttttttcttt
     1261 tcttgtgtag tcatgggtta ctccgtccca ttcatttttt attttttctc cacttatata
     1321 tgctgcactt gctactgcac ttttgccttt tcctcttgat attatgttta ctgaaaaatg
     1381 aaaactgtct gccattttta tcacttcctt tctttctttg ttgttttagg tggaggctta
     1441 atagtttttt tatatcctct ttgtgaatga gcgttttgaa atgatagaat taaaaaagcc
     1501 gactactgaa ttaatttttg ttgtttcagt atgtcggctt aattgttact ttcatttcaa
     1561 attttaaaag tcaagggcga gccttagcga gtttatttac ccttgacttt taaaaagcga
     1621 atggttgttg ctccctgcaa gggtttgact ccgcaggacg caagtaccct ttagggtgta
     1681 taattgcgcc cttgtaacca agggacaatt atgttatttc atctttagat gatttttcta
     1741 cattatcatc tattctttct tctaaaattt ccattatgtt taatcttatt tcttcatcat
     1801 ttaacgtttt tattaactta taaaattcat cttttgttaa atcaatactt tcttcaaaaa
     1861 tactttcaaa cactgcacct ttttctataa gtcttttgtt tcttgctttt ctttcttgtt
     1921 cattaagttt tttcttcaac tgtctttttt gattttgtaa ttgcttaatg ctttcttctt
     1981 tcttttcaat ctgttcttca atacttaatc ttttacttgc catcatgtat cctttcttaa
     2041 aataaaaaac gactagattt ttatttctaa tcgttcttgt tttaaatatt ataatttgct
     2101 atattgcatt ttaattttaa gtcttctata tatctttcca tgtaattcca atctggagta
     2161 cctctactgt ctatcggtaa tttaattttg atatctggca atactgtgct agatatttga
     2221 tctttatatt cagtattttt taaagcttgc ctaataattg aagttaaata gaatgctact
     2281 tctttattca attctttatt ttttaatttt aaacaatgaa ttttcatatc taggcttgct
     2341 ttatatttat gataaaagac tgctcctaaa aatgaaacag atataaaatt ttcaaagact
     2401 ctataatttt tatcatctat atcttcgtag taacctaaga taccattgtc aatatttgta
     2461 gcactaattc taggagtttt tccatcgagt aaatatcttt ttggaataga tgagcctgtt
     2521 ggtacttaac tcgatttccc ctttttttcg gtaataaata tttcttttta ttttgttgtc
     2581 tgatattttt cctacctgtc ctttgtagga tgagtatttt ctagattttc ttgaataact
     2641 ttttacttga agttttagct tttgaactag tcgttgtact ttctttttgt ttattatcag
     2701 tcctgatctt tttaatattg ctgttattct ctatatccta tttttcattc atgatattct
     2761 tttactaatt ttatcttaaa ttctgtgctg tatttgccat taaaaaactg acctccttta
     2821 gttagttttt tggcctaact tttgagggtc agttcaaaat ttgcgacttt taaatgaatt
     2881 ccaatattca attattaaga gttaatatgg tgcttgccaa taggaatcat tagaggcgaa
     2941 ttggaaatag ggtcacgtat aatttttgct tcaagattaa agatatcttt aactagttta
     3001 tcatttagta tatcttcagg ctttccctct gcaacaagtt taccttcttt aattgcaaat
     3061 aggtaatcag cgtatcttgc tgttagattt atatcgtgca aaatcatgca aatggttgtc
     3121 ttatattttt ggtttagatc agtcaagagg tctaatagtt ctatttgata tgagatatcc
     3181 aagtaagtag ttggctcatc taaaagtagg atacttgtat cttgggctag ggctagagct
     3241 atccatactc tttgcctttg acccccagaa agttcttcaa ctaggttatt tgctagatct
     3301 tcaacattgg ccttaaccat tgatctgttt attatttcaa ggtcatcttt tccaagactc
     3361 ttaaaaggct ttctgtaggg gaaacgacca cggcttacaa gatcagctac tgttattgat
     3421 tcagggatta ttggagattg aggtaatata gctatgtgtt ttgctaaatc tttttcttta
     3481 taagaattaa ttgatttatt atcaagcaat acttctccct ctaatggctt tataagtcga
     3541 gacaaggttt taatgagtgt tgatttccca caaccatttg acccaataat aactgatatt
     3601 ttttcttcag gtatttttat atttatattt tccaagatta ttttttcatc ataaccgcag
     3661 gtaagattat ttgaccacag acctttcatt atatattcct cctgttcatt tttattagta
     3721 agtatattaa atatggtgaa cctaacaagc cagttacaac acctactgga tatctagctg
     3781 gtaaaatatt ttgagagaat atgtctgata acaaaactag taaaattcca accaatccag
     3841 ctaatattgg gcttcttttc ttgccaatat ttaaggctat gggaccagct aaaaaagata
     3901 tacaagctat tggtcctgta attgaagtag aaaaagcagt taaagataca gcgcaaaaaa
     3961 ttaaaacaag ccttgaaagc tcgggatttg ctccaagtcc gattgctatt tcttcaccaa
     4021 gttcaataat ttctagtctt ttattaaaaa ataaaactaa tatagtagca ataatactta
     4081 ctattagaac aaggggtatg tcatctaact ttgtaaaaga taaagagcca ctgagccatc
     4141 tcataacttc ttgtaattca tatcttgcta ctttcaacaa taaaaatgag gtgcctgctc
     4201 ttgtgacagc ttgaaaacca atacctaata ttatcagtct tgctgctgaa aaaccatctt
     4261 ttttagctag taaaaataat attaaagatg atgttagtcc acaagttatt gaaataattc
     4321 cagtagttaa actatttgtt tttaatacca atatgcaaaa gaccgctgca atagatgaag
     4381 aacttgtgac accgattata tcaggacttg caagaggatt tcttaacata gtttgaaaga
     4441 taaatcctgc caatccaaaa gaccagccag ctataattcc tgctaataat tttggtaatc
     4501 taatttccat aatcgaaaaa ctagctccag gaacagtttc actatttaag actttaatca
     4561 aagttgaaaa agaataactt tcatctccga taagtaaaat gaaaaatgat agactgatta
     4621 ttattaataa aaatagtgag gaaaatagtg ttattctatt ttttcttttt tgaataccta
     4681 taattaaatt ttgcattagt tattaacccc tctatttttc atagttacat aaataagtac
     4741 tggacccccg attattgcag taattatccc tacttcaatt tcacctggtt tacctaacat
     4801 acggccgatt atatcacata taagcaagag ctctgcacct ataaaagatg aagaaatggt
     4861 cattgtgcgt atatctttgc ttataaataa gccacaaaag tgaggaacta taagacctac
     4921 gaagccaata ggtccaccaa ttgcagtaat acttgaacat aaaagcacac ttgcaattat
     4981 tgcaagtgat cttatcctat taacattaac tccaagacca acagccattt catcacccat
     5041 agctaaagcg tttaaatctg atgaaataaa tatagctatc aagtgaccta aaattataaa
     5101 aggtagtagt gtagatatag aagataatgt agctgctcca aggctaccta tttgccaaaa
     5161 tctaaatttg tctaagacgt tattattcgg taaaattaaa aaacttacaa aactgcttaa
     5221 agccatacta acacaagttc ctgataaggc aagttttata ggggtaaggc ctgcttttcc
     5281 gcttacagca atcgcgtata caaaaattgc acttactaag ccaccaatga ttgcaaaact
     5341 tatatggctt atgcttgatg aaattcctaa aaaagaaaga ccaattacta cactaagact
     5401 tgctcctgtg tttataccga gtatacctgg atcagctatt gggtttctag taactgattg
     5461 catcaataca ccgcttatgg caagactaga acctgctaaa attgcaaaaa tagttctagg
     5521 tattctttta tatataattg atttaataaa atcatcattt gtattaccca ttccaaaagc
     5581 tgctaaaaaa tctctgatat taatttcttt tgttccaagc tttaatgaca aaaatattgt
     5641 aataagaaga cctaggcaga ttacaaaaat tatgcctagg tttatttgtt ttttatttcg
     5701 catttttgca tgcatttcct aaaagattta ggtattcttc aatagtatag tttattgaaa
     5761 gtggtgttgg agtgcatgag gctgctaacg gtgtattatc tggaattaca gcaacggcac
     5821 catttttaat tgcatttatt ttacctaaaa gaggatcttt ttgtaaagct tcaagagttt
     5881 tatcatcacc ataagttatg attacatcag catcatttat cttatttgct tcttctgcag
     5941 aaatttcctt tgcaaaacta tcttcactct caaattcttt taatgattca gggaaaacta
     6001 gacctaaatc tgttaaataa tttgctcttg gatctttgct agtataaatc cagaattttg
     6061 atgtatctgc agcattaatc atagtaaata atactttttt tcctttgatt tttcctttga
     6121 tttctggatg tttttctaat tctttggata tacgagcttc agtatttttg attaactcat
     6181 caccttcttt ttccatacct aaggcttttg aatcaatttt aatcatatct ctccataaag
     6241 tttgccaagg tttagatttg tatgctgcta caggagcaat ttttgataga gtgtcataat
     6301 cttctttagt tataccagaa taacctgcta agataacatc tggtttagaa tttgatattg
     6361 cttcaaagtt aagtccatcc aaatcgtcaa ataggttagc tttaccattt agttctttga
     6421 ttttttcttc tgtccatggt aaaactcctt tatcagcact tacaccgtaa tttgcttttg
     6481 aaaatccaac aggaactatt cctaaagcta atgctacatc atgatttccc caagcaatag
     6541 ttgcaactct ttcaggtttt ttatctaata tagtttgacc gaaagcatga tctaaaacta
     6601 ttttatcagg cgcatgctct ttagaagtat tttcttcatt tttaacagaa ttagaagaac
     6661 aagcgctaaa aactatacac atagctaaaa tagctattag aaaaaatttg tttttcataa
     6721 aaactcctta aacatatttc aagtctattg tatcgataat aattatcatt gtcaatagat
     6781 gcagttacaa atttaataat ataatttttt caaaaaagga tctagttttt atttttagtt
     6841 aaattatgtc tatatttttc attaactcat caataaaaat ttgtttgcta atatctcttt
     6901 cttctgattt tgtttcaagg attattgcta catcattcat atttttaggt aaataccaac
     6961 catctggctt atctgaatat cccttgaagc ctaattgatt aaaagtagtt atttgaccag
     7021 taccttgatt gatgttttct tcaacttcat taaagcctat acttctcttg cataatccct
     7081 aacttgatct tctgtcctta aagtcatttt ctattcctcg tcactaaaat tatcttcaaa
     7141 actaataata tcattaggag tgcaagataa agccttacat attctttcta aattcttaaa
     7201 tgtaattggt ttatcctttc ccatttgtgc cataacattt gttgtaagtc ctgccatagc
     7261 tattacatct gttttcttta gtcctttttt tgctaactgt atccataatg gtttatagtt
     7321 aagtgccata atatccctct ttttttcttc attagattta tttaattata gcataaatat
     7381 tgatttcatt caatcttaca ttgatttagt gatttgtttt agagaatttg ttgtgttatt
     7441 ccgtccttat tttgccataa attgttttaa gtgggacctc ttatccttac catttttacc
     7501 tcctaatttt gagtataaaa aagacgatag agtttttaat ttctatcgtc tgagatttac
     7561 atattaaatt ttcatcacaa aataagactc tttaaagaat ctttaaattc attggtatgc
     7621 tgcttacaat atccattatt aaaatggata ttgtaagcag cacaccaact atttattttt
     7681 tgagttttaa actttggtag aagtcttgaa ctccttatat ttacataact atttgcctct
     7741 ataactgtta tgacacgaaa ccaacaagca agttcaaaca cctccatatc tttattcaaa
     7801 tgaggactaa gatattcaca aactttatca taaacctctt tatctttttt cataaaaggg
     7861 gcatacaact tagcaaattt atcctaaaat tttttgttgc ctttatcaat catttcaacg
     7921 ctcctttaaa tataaaaatg atcctatcaa tctttatatt gatcctattt tctaattgat
     7981 accttgcaag aaaggaataa tagctgttcc tataccaagt aggaatgtaa taaatgcaga
     8041 aagtcatata ctgtcattct tttctattaa atcattttga agtgtctcaa agcatccatg
     8101 atggcttctt ctttttcagg tgtacactgt ggaataattt gtttatcctt tttagacttg
     8161 ttgtaatgtt ctcgtaattc tattccacat ttctttttta tctgtgcaat atataatgtc
     8221 gaaactttta attcaaattt attccaaaca tattctttga tttgagcata tgttgctttg
     8281 ctctccgcac ttgtcaaatc cagctcaatt tcaacactta tgtgcttatc gacatcgagt
     8341 ttggacaaaa gtgctaccgt ctcgacgtga tgcgtttgag gaaatagatc caccggctgg
     8401 actttcttca attcatatcc caactcttgg tatagtttaa tatcacgcgc catggttgcg
     8461 acattgcagg agatataggc gatgcgatcg gctcctgttt gggcgcttgc tttgataaag
     8521 ctttctgtca agcccttgcg tggaggatca accaagataa cggttggttg aatcccatct
     8581 ttaagccaat tcttcatagc attttcagct gtgtcacaga catagtgggc gtttgaaata
     8641 ttgttcagct gagcattttt tttactattc tcaaccgctt ctggaatcag ttcaacaccg
     8701 tagacttctt tgacatgctt ggcgactgat aaaccaatgg ttccaatacc agaataagca
     8761 tcaataacca cgtcatcttt ttttaactct gcaaagtcaa tggctgtttg atagagtttc
     8821 tccgccattt cagtattgac ttggtaaaag gctgggccag cgatttggaa gtcatttccc
     8881 aacatctggt ccgtaatata gtcttgacca taaagagtgc gccactcctt accaaaaatc
     8941 gcattggtat tctggtcgtt gatattttgc atgacagaca caatctctgg gaactgcttg
     9001 ataacttgtt caatcaattg gtcaacacga aaaacttttg gacgagttgt caccaaaacg
     9061 accatgattt gtcctgaata gtgaccacga cgcaccacaa gattccgaat caatccagac
     9121 tgttcctttt cgtcataagg ttttaaatca aaacgacgga gcaggtctcg aagagctact
     9181 acgacttggt caatgacagg atcctggata aagaaatctt caaggggcat gaggttgtgc
     9241 gaattcttac ggaaaaatcc tgtttccaag acaccattca ctcgacgaac gggcacctgc
     9301 gccttattgc gatacttgac tggatgttcc ataccaagcg tttcagcaac ttctacatct
     9361 gcaattccag caatcttgta gagactgtcc ttgacttgct tggttttaaa cttgagctgt
     9421 tctggataag aaaggtgtcc taaatccgcg attcctgaac gcaggtaagc caaatctaga
     9481 tcttgattac ggtgtggtga ctggacaagg tatttttcaa cttttccaaa gccaatcttt
     9541 ttattgacct tgaggacacg catgagaatt ttttcactcg gtaaagcatt ctctacaaaa
     9601 aagaccaaac catctacctt ggcaactcct gccccttcat gggtcaaatc aacaatttca
     9661 acttctacaa tatcattttt ctttaacatt cttttctctt tctattggcc gacaaaaaag
     9721 acggcaacgt tacggttacc atccattata ccatgaaatt tcttaagaac caaaactctt
     9781 gaagaagttg acaagggctt gccagaggga gcttaagaag ttaccaccgt cctctagcgc
     9841 cttatccgca tcaaagttaa ggttgatatt tttaaaactg tcgccagctt gtgatacgat
     9901 gctttgttta aggtcattta gggttttagt gaaatctgca ttgctgagga tatcactctt
     9961 tgagagattc aaggcaaaat tgatgatgat attgatctgg tttcctgtta tgacctgatc
    10021 aagtttgtaa ttttttaagg tatcttcaac aatcttgcgg acatcttctt ctgtcagatt
    10081 tcccttgctt tctttagctt tggcaagtcc tgacttgata tcagctaggg caacgtttaa
    10141 tttattagca tcatagcctg atttgtcctt gttttcagca ttgatatctg acaaagcctt
    10201 caactcttct tgagccaaat ctttattagc ttgtggcacc ttggctccat tagcctctag
    10261 cgaatagtaa atccctgcta aggcactttc tcctgtaacc ggaatagggg ctgctacagt
    10321 gattttggca tgttccatac ccagcgttac tgctgcgttt cggtacatat cctgagtcac
    10381 cttagtgata ttttctggtg tttcaatctt gacctcaagt ggcgatttgt cacctagctt
    10441 ttgaatcttg gctgatgaat acaactgtaa gctagagtca ttggccacat tcatgatttt
    10501 agaataaaca tcaggtgtca tggtcttgag ttctttggta tctgttgagg cattgtagcc
    10561 cagtttttta agagtttgat ttttttggtc ttcagatagg gaagaaccta ggacatattc
    10621 aggttggaca taggtttcat cgataacttt ttgaacatct gttgctgcat gaacgctatt
    10681 catagctgtt actgcccaca agatcgcagc gctagtcaga aagagtttct ttctcatagg
    10741 gaattgcctc ctttacttct ttagagtaat atatctatct taaagaaaac ttataacaaa
    10801 aacacctggt ctagccagat gttgaaaaga gagtgaaaca tttgatgatg taaaggttaa
    10861 gtcgtacctg tctagaataa taatagtttc ctccatttac atagagttca gcaccgtgaa
    10921 aaatggaaat ggggtgaata taactataag tctttccagt cctattacca agcaaggggg
    10981 caacagtctc acgagagtac tgtttggcta gagccagggt attttccttg ccattttggg
    11041 cgataaaatc gatataggca ggtccaaaat tataggcttg aacagctgtc cagatatcta
    11101 cacccttctt ctgcgccaga tagagattgc ctgtcagagt ttgaatgcct tgccgaatgc
    11161 tagaggcatt atcattgatg gtgttggtgg aaccacttgc agactcacta gactgcataa
    11221 catcgccttc ttttcctttt gtttcagtat aaatcatagc aagcacaagc tcttcgtttg
    11281 ctggggtgtc ttgttcactc aatatttctc gcaccatggg ttgataggtc atgacttgtt
    11341 tgacatcttg atgaacgcgg taagctttat agccagcaaa aaggaagact gctagtacaa
    11401 gcactcttcg aattcgttta aacattattt actttggata tcctcgatat ttttgattaa
    11461 gatagagtag gttccatttt cgttttggat aaactcaaca gactcggcgt cttgatagac
    11521 gttattggga acgatgagct caattccatt tgataaggag agtttttggt tttcaaattt
    11581 ctttaattgg cgactggcat caatttcatc aaattgaaca ggttctggta cggcttcttt
    11641 gacttggtca ataaagctca aacgagccgt cagattgttg tcaaaaaggt cattagccaa
    11701 tttctcaggt gacaattcat tgctttcttc taggttgttg aaaatagctg atttgacctt
    11761 ggattgaaat tgaaaatcat ctgtgttaaa agattcagca attctctggg ctgttttttc
    11821 cagttccttg atagattttt taggagaaat cttaggagcg acagcaagaa gattatctga
    11881 aaaatagttc aaaaaagtcc cgttgtactt gattcgtttt tcaatcaggt gatacttgcg
    11941 actctgaaga ttgaccacca aggcctcgtc agcacccgtt ccaaatccag gcaggttatt
    12001 ctgagtcagc ttgattggat tatcaacttc tcctccgagg tgggtcaagg tctcccgcag
    12061 ggcaattcgc aagaaagcga aatgttctac accttcttta gaaaattgaa caaaaatcaa
    12121 gtcattggtc ttgagatttt cagaaatgct aaactcctct ttccaaagat tagccagcgt
    12181 tactgatgtc tccaacaaat cgtctgtaat atgattgaag aagggatttt cttcttcgaa
    12241 aatcccagtc ttggcttcat ctgaatacac atgttcaatt tttttacgta ggtattcttc
    12301 gatttttgga gtaatattga gaaacttatc tgctaagaac agctcggtat catccggact
    12361 gaactggtga ataatggctt tcttaatata aatgtccata aaagttttag tcctcgtata
    12421 atgggaaggc atctgtcaat tctttgactg cacttctcac ttcttctaat acagcctcat
    12481 tttctgaatt cttaagggtt ttaatgatga gtgcagccac tttgcgactt tcttcttcac
    12541 caaatccacg tgcagtaata gctgctgctc cgatacgaat cccacttgtc ttgaatggtg
    12601 acaaggtttc gtaagggatt gaatttttat ttagggtaat attgacttca tccagcaagt
    12661 tttgagcaac ttttccgttt tctacaacct tagtcacatc aacaaggaag agatggtttt
    12721 cagttccacc tgaaataata cggaaatcag ggtcttgcaa gaagacatct gccatagcct
    12781 tgctgttctt aattacattg gcagcatatt ccttgaaggc tggatccaaa acttctttga
    12841 aggaaactgc cttagccgcc acaacatgct ctaaaggacc gccctgaata cctgggaaaa
    12901 tagctgaatt gattttttta gcaagttctt cgtcattggt caaaatcaaa ccaccacgag
    12961 gtccacgaag ggttttgtgg gtcgttgttg ttgtgatatg agcgtatgga actgggcttg
    13021 gatgaaggcc agccgcaacc aaaccagcga tatgggccat gtccaccatg agcttcgcac
    13081 cgacagcatc tgcgatttca cggaattttg aaaaatcgat aatttgagaa tatgctgaag
    13141 caccagctac aatcagtttt ggttttactt cttgggcttg tttcaagata gcatcaaagt
    13201 ctaagagttc tgtttcagga tccacactat aagaaacaaa gttgtaggtt tgaccagaga
    13261 agctaacagg agccccatga gtcaaatgac cacctgatgc caaatccatt cccataaccg
    13321 tatcacctgg ctcaatcaag gacatgtaag ccgcacagtt agcttggctt cctgaatgtg
    13381 gttggacatt ggcaaattta gcaccgaaaa tttcttttgc gcgttcaata gcaagagtct
    13441 ctacaacgtc tactacatca gttccaccat aataacggcg tcctgggtaa ccctcggcat
    13501 atttatttgt caagatagac ccttgagctg ccataacagc cttggaaact acgttttccg
    13561 aagcaattaa ctcgatatta ttttgttggc gttcttcttc tttggcaata gcattccaga
    13621 gatcagcatc atatgcttta aaatcatctt tgtcaaaaat cataggtctt ctcctttatt
    13681 gtgtgactag tccattagtt tgattttaca ataagaaaat caaactaaca gatgcgaata
    13741 aaccgtttct gcattttatc acaagtatag ccaacttttt cataaaatgc atgagcaccc
    13801 agacgatgat tggcagaatt taagcggata aacccataac cacatctttt tgcttcttct
    13861 tccaaccctt gtagtaaact tttaccaata ccttgacctt gcgcttgagg tgaaactgct
    13921 aaagctaaga tattaaatcc tgctttggaa tagagtgatt cgtaaacttc agcgtggaca
    13981 tatccaagta agacatgatt agctgcatcc tcatagccaa gtaggaaatg atgggaatcc
    14041 tgagacagtc tagctagttg gctagccgtt tcctctggac taaaagtata acccaaagcc
    14101 tcttggttga tgtcacatat cgctttcaca tctgtttctt gcaaatctct tagcatttca
    14161 agcctcctca aaagaaatct ctggcaaccg agcaagaata tcttctcgtt taattgcgcc
    14221 ttggcgtaag attttcacct tgtctccaga caaatccaca atagttgaat cctgtccagt
    14281 tagaaaagca tcgtcttcca gacccagaac ctcttggtca aaatccttca gaatttgttc
    14341 aaaggttaca ccacttgcct gacctgagat attggcagac ggcccaatca agggacctgt
    14401 ctctcgaatt aaatccagtg tgatagggtg actgggcatc cgaaatccaa tagttgcaag
    14461 gtcagaattt acccaatagg gaactcggtc attggcttcg agaataatgg tcaagggacc
    14521 tggcaaaaag gtctctacaa gtttttgtag ataagctggc tgattcttag aaaagtgcaa
    14581 gatgtcctcg aaagaggcga tattgagatt gagtgcctta tctctaggac gacgtttgag
    14641 ttggtaaaca tggtcgacag ctttttcatc taaggcctta gcaaaaagac cgtaaaccgt
    14701 ctctgtaggt agaacgacag ctccaccatt ttccaactct tgtctaatcc tgtccatcat
    14761 caaccacaac catcctgttt tgaccaaatt ggtccttgag tgttcgaact cttttttcag
    14821 gaagatgttt cctaaaaagt tcgggaacac tttgaccttg cttgtatcca atttcaaggt
    14881 aaatcttacc accatctttg agatagtctt ttgcatcttc cgcaattcta cagtaaatag
    14941 ctaggccatc ctcgtctgca aagagagcta gatgaggctc cgaatgcaaa acattcaagc
    15001 ctacctctga ctcatcttca cgagagatat agggtggatt ggatacaatt atatcatatt
    15061 tttcagaaat ttctgcaaaa caatcagatt ttttaaaaaa tatattaaga ttttgattgc
    15121 tagcattctc tgatgcaagc tctaaggcct cttgagaaac atctgctgct gtcactgacc
    15181 aagctggtct attttttgct agagcgagag caatagctcc actacctgtt ccaatatcca
    15241 gaactgagag attcgtctca agattttcag ttagaataag ctccactaac tcctctgttt
    15301 ctggacgagg aatcaaaacc cgttcatcca cctttaaatg cattccataa aaatctgcct
    15361 gtccaatgat gtactgagct ggcttgtgag ctgctagttg ctggtaaata tcttctacaa
    15421 attgtttttc ttcctctgtt gtcacctcct gctggagggc aaaaataaag tctgtaaaag
    15481 atagattttt cagactacga tagacaaaag agaggctttc cgcttcctct ccttgtctta
    15541 tcaactcttc ttcaaaattt gaaaataatt gagctaattt cattatttgt ttaattcttc
    15601 tagtttttgt gtttggtcat aaagcaccaa ggcatccaca acttcgtcca atttaccaga
    15661 caaaatcgta tctagttttt ggagggtcaa gccgatacgg tggtctgtga cacggttttg
    15721 tgggaagtta taagttcgga tccgttctga acggtcacca gtaccgattg tcgacttacg
    15781 ctcagcgtcc tgctcatctt gagcaatctg agcaaagtgg tcagcaacac gggcacggat
    15841 gattttcatg gccttctcac ggtttttctg ctgggtacgt tcttcttgca tctcaacctt
    15901 gatattggtt ggcaagtgaa cgatacgcac ggcagtcgca accttattga cgttctgacc
    15961 accagcacct gatgcgtggt aaatatcaac acgaagatct tttggatcga tatcgtattc
    16021 tacttcttcg acttcaggca tgacaagaac tgtggcagtt gaggtatgaa cacgaccttg
    16081 gctttctgtc acggggacac gctgcacacg gtgggcacct gattcatact taagcttaga
    16141 gtatacagac tgacctgaaa ccatagcaac cacttcttta aaaccaccga caccattcat
    16201 agaggcttcc atgacttcaa agcgccaacc ttgggcttcc gcatactttt ggtacatagt
    16261 tagcaaatct ccagcgaaaa gtgccgcttc gtctccacca gctgctccac ggatttcaag
    16321 gatgatattc ttgtcatcgt ttggatcctt tggaaggagc aaaattttca gtttttcttc
    16381 atattcttct ttttcagcct tggcatcttt gagttcttgc ttggccaatt cttccaagtc
    16441 cgcatctccg cctgattcct taatcatctc ttcggcatcg acgatatttt gaaggacttg
    16501 tttatactca cggtaggcta ttacggtgtc acgattggaa gcttcttctt ttgaaagctc
    16561 cataaaacgc ttggtgtctg aaacgacatc agggtcactc agcaattctc ctagttcttc
    16621 ataacggtct tctacagctt gtagttgatc atagatgttc atttttcttc attctcctta
    16681 ttgatttcag gggcaaaata atgtttacgg caaaccgaga tataggtttc attaccacca
    16741 atctggatct gttctccatc gtaaacgggc agtccatcct gtgttcgcaa caccatggtc
    16801 gcctttttct tgcaatactg acagatggtc ttgatttcgt caatcttgtc tgctaaaagc
    16861 aagagatatt tggaaccttc gaacaattca ttgcgaaagt catttttcaa gccaaaagcc
    16921 atgacgggta tgtctaactc gtccacaaca cgagctaggt cataaacatg gtggcgtttg
    16981 agaaactggg cttcatcgac caaaacacag taaggttttt ctggtaggtc tcggatatag
    17041 ccaaagatat ccgttgtttc ctcaatagca agggcagggc gtttcatgcc aattcgactc
    17101 gacacatagc caacaccgtc acgcgtatcc agagccgagg tcataatcac aacacctttt
    17161 ccttgctcct cgtagttata ggccactttg agaatctcaa tcgttttacc agagttcatg
    17221 gtcccataac gatagtacaa ctgtgccatg tttcttgctt cacgtccatt tctaaatttt
    17281 tgctacattc tagtatatca taattttctt aagctttaaa cggcaaaatg tggtaaaatg
    17341 gaagaaatca aaactagtgg aggaagctat tatgccattt gtacgcatcg atttatttga
    17401 aggacgcacg ctcgagcaaa agaaagctct tgctaaggaa gtaacggaag cagttgtccg
    17461 caacactgga gcacctcaat ctgctgtcca tgtcatcatc aacgacatgc cagaaggaac
    17521 ttacttccca caaggggaaa tgcgtactaa ataagctagc ttaagcagaa ttgcttaggc
    17581 tttttcaatc tccaagtagc acccattgaa gaaatagtct aaatttgtta caatttgaaa
    17641 agagacttgg aaaattccaa gaaaagagca attaattaaa ggaaacatta tgattacacg
    17701 tgaatttgat accatcgctg ctatctctac tccactaggt gaaggagcta ttggtattgt
    17761 ccgcctgagc ggaacagaca gttttgctat tgcgcaaaag atttttaaag gaaaagactt
    17821 gagtcaggtt gctagccaca ctctcaacta cggtcacatt attgatcctc tgactggtaa
    17881 agtcatggac gaggttatgg ttggggctat gaagtctcca aagaccttca ctcgtgagga
    17941 tattatcgag attaacaccc acggtggtat tgcggtgacc aatgagattc tccagctagc
    18001 tatccgtgaa ggagctcggt tggcagaacc tggtgaattt accaaacgtg cctttttaaa
    18061 cggtcgcgta gatttgacac aggccgaggc ggtgatggat atcatccgag ccaagacaga
    18121 caaggccatg aacatcgcgg tcaaacaact tgatggttcc ctttctgatc ttatcaataa
    18181 tatccgtcaa gaaatcctta acacacttgc ccaagttgag gtcaatatcg actatcctga
    18241 gtatgacgat gttgaggaag ccactactgc tgttgtccga gagaagacaa tggagtttga
    18301 gcaattacta accaaactcc ttaggacagc acgtcgtggt aaaatccttc gtgaaggaat
    18361 ttcaacggct atcattggac gtcccaacgt tgggaaatca agccttctca acaacctctt
    18421 gcgtgaggac aaggctatcg taacagatat cgctgggaca acacgagatg tcatcgaaga
    18481 gtacgtcaac atcaatggtg tacctctcaa attgattgat acagccggta ttcgtgaaac
    18541 agatgacata gtggaacaaa tcggtgttga gcgttcgaaa aaagccctca aggaagccga
    18601 cttggttcta ctagtgctaa atgccagtga accactgact gcgcaagaca gacaacttct
    18661 tgaaattagc caagatacca atcgcattat tctacttaat aaaaccgacc tgccagaaac
    18721 gattgaaact tcgaaactac ctgaagacgt tatccgtatt tcagtcctta aaaaccaaaa
    18781 catcgacaag attgaagagc gaatcaacaa cctcttcttt gaaaatgctg gcttggtcga
    18841 gcaagatgct acttacttgt caaacgcccg tcacatttcc ctgattgaaa aagcagttga
    18901 aagcctacaa gccgttaatc aaggtcttga gctggggatg ccagttgatt tgcttcaagt
    18961 tgacttgact cgtacttggg aaatcctcgg agaaatcact ggggatgctg ctccagatga
    19021 actcatcacc caactcttta gccaattctg tttaggaaaa taagaaaaat ccatgatcct
    19081 tcattcggtc atggatttta ttgtctttat tagtaatctg gtcttaagac ccctgttaca
    19141 gttgccttag ttgcttcgta gtcgccatct acgacaacct tgataatgcg tttggcatct
    19201 tcttctggtg ctggaacaag aggtagacga gtgggtccag cttcaaatcc catatagtta
    19261 agaattgcct taactggagc aggacttgga taagagaaga gagcattaac cttaggaatg
    19321 aatttacgct gaattgctgc ggctttcttc atatcgcttt ctgcaatggc agtaaacatc
    19381 tcgtgcattt catccccatt tgtatgagag gcaacagaaa taaccccatc cgccccaagg
    19441 ttcatggcat ggaaagcatc tccatcctca cctgtataaa tcaagaactc ttcaggcttg
    19501 tgctcaatca agtaagccat attagccaag ctagtacatt ctttgacacc gataatattt
    19561 ggatggtcag ccaagcgaag catggtttct ggagtcaatt cgacaactac acgccctgga
    19621 atgttataga taataattgg taggtcagaa gcatctgcaa tagccttaaa gtgctgatac
    19681 atcccttctt gagaaggttt gttgtagtaa ggaacaatag caagcccagc tgcgaaacca
    19741 ccaaattccg ctacttcttt gacaaactca atagagtcac gcgtatcatt agtacctaca
    19801 cccgcaatca aaggaacgcg tccattgaca accttttgta cagccgcaaa caactccaac
    19861 tcctcatcgt gggtcaaagt tggactctca gcagtcgttc ctgcgagaag aattccatcc
    19921 gtatgatggg ccaataaatg ctcaatcaag gctggaatag catcaaagtt aatggaacca
    19981 tcctcatgga agggggtaat aaaggctgta atgattttac attcttttaa atcttgataa
    20041 gacacgaaaa cacctctcta tttcaaagaa ggagttcatc tgaactccta aacgatatga
    20101 ctattttaat tcaaatttca attcggctgt tggacgaacc aatccacgtt catgaagagt
    20161 ttcagcaatc tgaactgagt tccaagcagc acctttgaga aggttatctg aaacaaccca
    20221 catgtgaatt cctttttctg catccaagtc tttacggata cgaccaacaa aggtatcacg
    20281 cgaaccaact gcattgatag cttgaggata gatttgatga gctacatcat cttcaagaac
    20341 agcacctggg aaggctgcga tagctgcttt tacttcttcg attggagcca cttcttttgt
    20401 ttcgatataa acagactcag agtgagctga caagactgga atacgcacac atgttgcaga
    20461 tactgcaatg ctatcatctt ccataatttt cttagtttcc ttggtcatct tcatctcttc
    20521 gtacgtgtaa tcattatcag tgaaaacatc aatttgtgga agagcgttaa aggcgatagg
    20581 ataatgtttc ttgtcaccac ctgaaggcaa aatttccgca tgcaaatcac atggtttcac
    20641 accatcattc aagacttcac gaagttcacg ttgtgtctca agaattgctc ccataccagc
    20701 acctgaaacg gcttgataag ttgaaacaat gatacggtcc aagccccatt tttggcgaac
    20761 cggctcaaga gccaccatca tttggattgt tgaacaatta gggcaggcaa tgattccgtt
    20821 gtgagcatca agtgcatgag cattgacctc tggaacaacc aaaggaacat ctggattttg
    20881 acggaaataa gatgtattat ctactactac cacgccagct tttactgcgt atggtgcata
    20941 cttagctgat gtagaactac ctgctgaaaa gagagcaata tcaactcctt caaaagctgt
    21001 ttcagtcgtt tcttcaattg taatatcttg atctttaaat ttcaatgact tacctgctga
    21061 acgtgcagaa gcaaggtaac ggattttatc gattggaagt gttgattctt ccaacatttt
    21121 tatcatctga gcaccgacgg cacctgtcgc gccgactaca gcaactgtat atcccataaa
    21181 taacctcttt cggaattttc taaaaatttc tataatagaa gtattatact actttttcca
    21241 tgaattgcaa agctttttca tcattttttg gaaaataaaa atcccagtcg ctagactagg
    21301 gactaagagg catcttcatg tgatgagcag gttcacacaa ctcatcaagg tccgctcctg
    21361 cgttatgacc tccttatgct caatagtagt ccgaagacta cctatcgact catcgcatat
    21421 tctatattac tagagatact tgattttgtc aataagaaat tttttcgatc gagtataaca
    21481 aaaaaactct cgtattcaag agtttcccta tacatatcat gctaattgcc gggattgaac
    21541 cggcgacctc atccttacca tggatgcgct ctgccaactg agctaaatca gcttacttaa
    21601 gaagtatact atattcagaa aaacttgtca agtttcctta gaaattttcc ataggaaaaa
    21661 gccaggtaag aactacctag cttatcttct tctatttact taaatcaatt cgacgaccaa
    21721 ttttaccaat aataatcgct ccaataatca atgaagcaaa ttcaccgatt cctgttgtaa
    21781 accaagtaag gaagaatggt aattctgcta caatatttaa ctctgcagcg atagtaaaca
    21841 tggaaattga aaagaggatt gaaaagaaga aatgatcttt tcgaatcaat ccgttaaaga
    21901 ggtaatcctt gctatatttt gcaaaaagcc aaacacctaa actgaggaat actaaggttg
    21961 aaccaccacc aacaaagaca tctagcagtc cgaagctaaa gaaattagca atcatacaac
    22021 cgatggtaac tccgatgatg tacttaggat tgtaaaaagc cataaagttc atcatttctg
    22081 aaatacgaaa ctgataagca ccatagctga tggcatttag gggcggtgtg acagtcaaaa
    22141 cgacgtagat agcagcgacg attgcaatat ctgcaacatc acgaatagtt aattttttca
    22201 tcttttctcc tttggcggtt gcccgcgtgt aatatgcttg gtgaaagaag ctaagcacca
    22261 agggttgctt tattcaaccc tactagtata gcacaatagc ctgctttatg ctatacttaa
    22321 cacatgaaaa ttcctattca aaaatttttt aacaatgaaa tcttagccta tctctttttt
    22381 ggtatagtga ctactcttgt tgctatacta ttacgattag tcatttatca gctaagtcat
    22441 caagaactcc ttgctacggc cttggcaaat attatcggta ttttatttgc ctttatcaca
    22501 aatgatacaa ttgtatttaa gcaaaaaaag aaaaatagac ttatccgttt agtgaaattt
    22561 tctcttgctc gcctttctac ttttctgtta gacttgtttt taacttttct ctttgtaacc
    22621 caatttcctc acatcatagg gcaattcgta actgaaaaca ttgataagat aaatgctatt
    22681 gaaacaataa ttgcacaaat attcattatt atcatcaatt atatcttgag caaggtctat
    22741 atttttagaa aataatgctc catttatgag ccttttaatt gccttctata atgatttagg
    22801 atacaatgaa acacgaaaca ttgaaaggaa aacagtatgt taaaaaatct aaaatcgttc
    22861 ttgcttcgag gaaatgttat tgaccttgct gtcggtgttg taattgcctc tgcttttggt
    22921 gctatcgtta cttcacttgt aaacgacatt atcactcctc ttattttaaa tcccgctttg
    22981 aaagctgcta aagttgaacg tatcgctcaa ctttcttggc atggagtcgg ctatggtaac
    23041 ttcttaagtg ctattatcaa ttttatcttt gtgggtaccg ccctcttctt tattatcaag
    23101 ggcattgaaa aagcacagaa actgactggc ataaaggaag aaaaaactgc cgaaaaaaaa
    23161 ccaaccgaat tggaagtcct tcaagaaata aaagctctcc ttgagaaaaa ataatcgatt
    23221 aaaaggatct agcgcaaagc taaatccttt tttctttact ctttgggtaa cttgcctgct
    23281 ttttcaagca tttttttgat aagataaggc atcttaacat tctcccgccc ttttttctca
    23341 atcagttttt tcacaaattc tggcatttgt aaatcttgag attcggctaa gatattttta
    23401 gtctcatctg aaggcactaa ctcatcaaag gtttcttctt ctgggagaaa ttccttaaac
    23461 tcttgatttt cattgactct aactgtattg accaaggcat caatcaaacg agaatctgta
    23521 tttggcattg gtggacgatg gtagtttacc ccaaattcct gacataaatc ataacattcc
    23581 acatcattgt caaacaagac ctcaatatgc tcactgatga aactaatagg tacaaaaata
    23641 taatggtctg gatgttctgt ctgttctctg agatactcca aaacatctgg tttaatccat
    23701 ggaataccaa tatcactctc actctgccaa gtgttggtat attgttctga actcaagccc
    23761 agtttttcag cgactagctt gctattttcg aaaatttggt ctatataagg atctccaaag
    23821 tccaaggcaa aaataggcac actatgggct gaaaagatga ctttaaagct gtcttgcttt
    23881 acttcttctt ttaaaatctt agcaatttca tctgcccaat agtttaagag cgcttcttcc
    23941 tgataccagt ccttaatgac caaaaattga atttgtttgc tttctaaaaa tttttcatag
    24001 cccatgacag agtagaaaga ataatggggc tccaaaatca agcaaataca ctgttcaatt
    24061 ccgtctgctt ccatttgacc gatcacatct ggaataaagg gactggaaaa cttattagca
    24121 aagtagacac tgtattcatt ccccagccta gcttctacca aggcaacctc ttgacgggta
    24181 attttttgca gaggcgtgcc tccaattcgt acataattat catagagagt ctgaatctcg
    24241 tggtcttggg gtctcatccc acgacgaata tttgtgaaaa aatcagctac accttcaaag
    24301 gtaatctctt ctggtgaacc gaaggtcatc attaaaattg cttttttcat gactgcttcc
    24361 ttgtgatgtt tttatcaagt ttattttatc attaattcat cgataagtaa acgctagcat
    24421 agggacattc tcaatcttct gtcttttgtt tttctcttct ttctatgata caatggaaaa
    24481 aataaattca aaaggagttt ttttatgact tatccaaatc tcttggacca cttcttaacc
    24541 tacgttaagg tcaacacgcg ctctgatgaa cactctacta ctactccaag tacacagagt
    24601 caggttgact tcgcaacaaa tgtcctaatt cctgaaatga aacgtgttgg actgcaaaat
    24661 gtttactatc taccgaatgg ttttgctatt ggaaccttgc cagccaacga tccgtcttta
    24721 acacgtaaga ttggttttat atcgcacatg gatactgctg attttaatgc tgaaggagtc
    24781 aatccacagg taattgaaaa ctacgatggt ggtgtgattg aactagggaa ttctggtttc
    24841 aaactcgatc cagctgactt caagagtctt gaaaaatatc caggacaaac gctcatcaca
    24901 acagatggaa caaccttgct aggtgctgat gacaagtcag gaattgctga aattatgaca
    24961 gccattgaat atctaactgc tcatcctgaa attaagcact gtgagattcg tgttggtttt
    25021 ggtccagatg aagaaatcgg tgttggtgcc aataaatttg atgcagaaga ttttgatgtg
    25081 gattttgcct acactgttga cggtggtcca ctaggtgaac ttcagtacga gactttctca
    25141 gccgctggtg ctgaattgca tttccaaggc cgtaatgtcc accctggtac tgccaaaggg
    25201 cagatggtca atgcccttca gctagcaatt gattttcata atcaacttcc agaaaatgac
    25261 cgacctgagt taactgaagg ttaccaaggt ttttaccatc taatggatgt gacaggtagt
    25321 gttgaggagg tgcgtgcaag ctacatcatt cgtgattttg aaaaagatgc ctttgaagcg
    25381 cgtaaagcat ccatgcaatc tatcgctgat aagatgaatg aagaacttgg gagcgaccgt
    25441 gtcactctca acttgacaga ccagtactac aatatgaaag aagtcattga aaaagatatg
    25501 actccaatta ccattgctaa agccgttatg gaagatctag gtatcacgcc tattatcgaa
    25561 ccaatccggg gtggaacaga cggctctaag atttccttta tgggaatccc aactccgaat
    25621 atctttgcag gtggcgaaaa tatgcacgga cgttttgaat acgttagcct tcagactatg
    25681 gaacgtgcag ttgataccat cattggcatc gtagcttata aaggctaaaa agacgaggta
    25741 gctcagctac ttcgcctttc tttttattct actggttttt cttgatttcc agtagttgta
    25801 gaagattctg ttgtttcatt ttctgaagtt gattcagcag gtttagaatc tcttgtattg
    25861 cttggtttgt tttcgtcgct agcagtttca atgttagatt ctgcagttgc gtttggttgg
    25921 ttctcagcac tggtgttatc actatttgct tcagcatttc ttgctggact tgtttcttca
    25981 cttgcgctag cttttgactg gatttgatga ttcaaaacta gaatagcttt tgtcgattca
    26041 agtaaagctg ttttgtcttt actcttagca gaaagttgat ctaataatgc atccacctta
    26101 tcaaagtccg catcagatcc attattactt tctaaataag agtgaagcga catgagaata
    26161 tcgtagagtt tttgatagag tacaagtgtc tgagaatctt gctcagcatt ttccttttct
    26221 tgttgaaggg cgctagcgat acgagtcaaa acatctttta cctgactgtt tacttcatcc
    26281 aagtctgcat cagccttgtt tgtggcagct tttagatttt ctacttcttc tgccaaggat
    26341 tgtctgattc cttcttcatg gatttgttcc aagagttgat ttgccttgtt caaaaaactt
    26401 tctacttctt ccttgctatc tgtcgcagat tattggttgc tatctaccat gtactcctaa
    26461 aacaggagag ttataatcca agattacaag gccttacaga aataagaaat ccagataaga
    26521 caatgttcgt ccaagacgct attcgcttcg cacagcagca cggattcaat atactttaat
    26581 tttaaagttt aggtgtcaag acctcttttt agtgtgccca aaatttagag aagtaatcaa
    26641 tcaactaact tttatttttt tcaaactttc agtaaactga cctaaagcta actcaatctg
    26701 tctttgttcg ataggcttgt ctttgtagat gcttctgcta tcagctagaa gttgatctac
    26761 ttttgccaag actgccttct catcaaaagt tccaggttga tagttggatt gcagggatgg
    26821 aatcttgttt ttcaaagccg cttcatatcc cttagtttga accttgatgt agtgattgtg
    26881 gtcgccacga ggaatcacaa aaccttctga atcttcactt ataattcgat tggcatcaaa
    26941 accatgacca tcttcttcct catggtggac atgtagtgac ggattactta atacagaact
    27001 agaagaactt cctacctttt ccgtgttaga gtgtgatggg ggattgttaa gagatgactt
    27061 aggaatatag tgatagtgac cccatgtctt actatataag catcacctgt atctctgaca
    27121 atatcattag ggttaaagac ataaccatca tctgctgcag aaacaccatt attcggtgtc
    27181 accgacaaag attgactgag agctgtagta ttctctgata attatacttt tgcagctgct
    27241 aattcacctg ccgacaagtc actctcagga atgaaatgat agtgaccacc atgtggtact
    27301 atagtagatt gaaatagaat atgagcaaat tgataagggg attttaaagt aatttctaac
    27361 aatgatttag aaactatgat gtgctattct aaattcaact cactatatat aaccatcatc
    27421 ggtagtataa cgtccctgta attttgctac agatacttct gcactagctc ctttatcgtc
    27481 tttaccatgt tcttgttttt ggcgattgat ttcatctttt attcgtacat tttctgcatg
    27541 agcttgatct ttaaggtaaa cataatactt tccatctacc ttaataatat atcctccctt
    27601 aacctaactg acgatatctt gatctttcgg ctgatagttg ggggctttca ttaatagctc
    27661 ttcactaaag agcgcataca aaggaacttt accattatag cagtgataat gatcgccatg
    27721 agaagttaca taaccttgat ctgtaatctt aataacaatt tgttttgctt gaattccttc
    27781 tttttgacta acctagtctg gagtcaaatt ttcagtcttc ttagtgtctt tattactgtt
    27841 tacatatgaa acacgatttt tatctgtatt ggcctgttag ctatgttggt tcagagcata
    27901 aacacacaga cttaaggaaa ggataacaac agatccagct gttatatatt tctttttaaa
    27961 tttcataatt acctcatttc tataattatt tatatgatgt cttcattatt aaatgattaa
    28021 ataaattaat taaccaatta attaactagt aaatattcca cctcttttta agttgtatgt
    28081 caagaaattt tatatattaa taataaaatg aaattctccc aaagtcagag ttttatttct
    28141 aacttttgag agaacttcat ttttgattca gactttttct actgctattc cttacgctat
    28201 gagatcagat aaattctttt ttatcacttc tccacttggc aatcttaatt caatcgttcc
    28261 atccatattg aatataacac tatctaaacc taatccataa ctagctgtaa atttttctaa
    28321 tttttcttgt acaggatcta ctgctggagc ttcctctaat gctggatcta acatagggtc
    28381 actccccaca ttcccttctg gattcaacat tccattatcc gttgagtttt ctggttttac
    28441 aggttttttg tttggtgcct ctggtaaaga atctgctggt ttattttctg ttggttggtt
    28501 ctcaactgtt ccagtagata cttttccatt ttcagatggt ttattttcac catttccttg
    28561 aggtgcttct cctgtaaaat ctgccatatt ctttttaatg acttctcccg atggtaaata
    28621 taattcaatt gttccgtcca tattaaacaa gacattttct agcttcatcc cataactttc
    28681 agcaaatttt gctacttttt cttgtacagg atccactgta ggaacttctt ctaacgttga
    28741 attactagta ctattcccag tttcagaaag tttttctttt tctaccttct cactagtctt
    28801 tggttcttct accttttcat caagttttga gttttcttgt gctttattcc ttttaaattg
    28861 tggtagaata cttggtttat cagtttgatt ttctttttcc aagataggta cttccacaat
    28921 ataagtcgat tgattgtcca aataagcatt tgccatgaag gttacaggaa ttttatttcc
    28981 ggccgttctg gttgttcctt ggtttaattt cggaatcggt aatttaattt caccaacttt
    29041 atagttattt tctaaataag catttccatg aaattcatca aacactctga ctaaagcatc
    29101 agttccttta ggcactgcaa attgagggtt cactcttaaa taagtatccc ctgcatggaa
    29161 aggatagaaa atcgtttgac tggccatttt gtaagctaaa gaggttggaa ctgtaaatgt
    29221 accatcataa cttacttctg gataatcttt tgaagcgata gtatacttaa atgtttgtcc
    29281 tggtaaataa ggttgatcta attcaaagtt tgcaatattc cctactcctt ctccaaatac
    29341 tttaccagat actttctcca atacttttcc atctggtgtt attaatttta ctagcatatt
    29401 gatacctaat tttttctcca attcaggcgg aaaactaaaa gaaacgcgtt tttgaccatt
    29461 ggctagagta aagttttgat tattaaacgt actatttttt aacaaattaa caacattcgt
    29521 taattcttct ccagtataaa ctttattccc ttctttttta gcaactcctt cttcgggttt
    29581 aaacagttca tagttactgt gagaatgacc aattccaacc ggtttatgtt catcaatcgg
    29641 atctgcatga tggtgatctc catgcggata aataatcgca tttttttctt tattcacgac
    29701 aatactttca cgtttgacac catattgttt cataatgcca gcaatttttt cttcgatttt
    29761 tttatctaaa tctttcattt ctttggcatt acttggataa tcctgttcat gagatgacaa
    29821 agaatctaat ccattatgac tagttttaac ttcctctaaa tgtttttgcg cagccttaat
    29881 ttgctcttct gtcaagtcct tcttgaagaa ataatgattg tggtctccgt gactcatgac
    29941 aaaacctgat tcatcttcag cgataatacg attagcatca aatccgtatc catcttcttc
    30001 atgtttctca tgtgaagttc ctggattgat tggaagagat ggagaaggtg ttgctagact
    30061 attgtttgga agagtcggtt gcccaatttg atttgatttt ggaatgtaat ggaaatgatc
    30121 accatgtctt acaatataag ctgtagccgt ttcttcaacg atatcttttg gattaaaaat
    30181 ataaccatca gatgctgaag agagctcctt acttgtcgtt aaagaagaag gattgcttga
    30241 aagactgcct agactagaca ctacttcatt aggttttgca tttgtagaaa ctgtagaacc
    30301 agttccactg ataggcacca ttctggcaat cttttcttct aaggcagaaa gcttgctgta
    30361 aggaataaag tggtaatggt cgccatgcgg aatcgcaact ccatttggtg tacgactgat
    30421 aatcttagca gggtcaaaga ccaggccatc tgattcactg taacgttggg cgctaggtga
    30481 atcatagagt tccttcaaaa gactctggag attttcagat ttatttgctg gcttgctagt
    30541 tgatcctttt gctacagatt gcgtgttatt gtcactagct gttgaagaat agcttaactg
    30601 actcggttgc atattttttc cagccagatg tgctttagct gctgctaatt cactagcaga
    30661 taaatcgctt ttgggaatgt agtgatagtg acctccatga ggaacgatat aagcattacc
    30721 cgtatcttcg ataatatcag ctggattaaa gacataacca tcatttgtcg tatatcgtcc
    30781 ctgagacctt gctacagcaa cattagagtt aaccttctca ttatctttga catgttcttg
    30841 tttttgacga ttgatttcat ctttagttcg aacattatca gcatgagctg catctttcag
    30901 gtagacataa tattttccat cgaccttgat gatataacca cccttgactt cattgacaat
    30961 atcagcgtct ttaagttgat agtttggatc cttcatcaag agttcttcac taaagagggc
    31021 atcataagga actttcccat tatagtaatg atagtggtca ccgtgtgacg ttacatagcc
    31081 ctgatctgta attttgatta caatttgctc agcctgaatt ccttctttct ggctaacctg
    31141 gtctggtgtc aagttttcac ttttctgact tgactggctg ccatccacat aagagacacg
    31201 attattgtcc ttattttcct gcgaacgatg ctggtttagt gcataggcac atagactcaa
    31261 ggatacgata acagctgatc cagctgctat atatttttta ctaaatttca taaatccctc
    31321 atttcaataa atgatgaagt tttttctcaa cttcttttac tttattaaat agttttctaa
    31381 accggttatt taaccattta attaaccagt aaatagttta ctatttaaaa ttacttttgt
    31441 caagtttctg ttacgttttt ctaaaaaaga gaagtaacac gaaaggttac ttctccataa
    31501 aatatgctcc attcatttta ctactgtatc ggagccggtt gacttttttt taacaaagcc
    31561 aagagactat ctacttctgc tgaaatagtg ttattatctt tcgttccgag aagaagacta
    31621 ctttttagac cagtcaatgt ctccatagca ttttgtctaa tactagaatc tgttactttt
    31681 tctagcaagg cctccgc
//
LOCUS       DBERXF010000025        30631 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.25, whole genome shotgun sequence.
ACCESSION   DBERXF010000025 DBERXF010000000
VERSION     DBERXF010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 30631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30631
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.25"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(93..945)
                     /locus_tag="ACL8JK_001266"
                     /pseudo
     CDS             complement(93..945)
                     /locus_tag="ACL8JK_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            936..1001
                     /locus_tag="ACL8JK_001267"
     CDS             936..1001
                     /locus_tag="ACL8JK_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HGS1786145.1"
                     /translation="MISKFFPILMLVMDIIIIVGG"
     gene            1105..1974
                     /locus_tag="ACL8JK_001268"
     CDS             1105..1974
                     /locus_tag="ACL8JK_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="HGS1786146.1"
                     /translation="MKHKKVLIIGYGIMTRGILKILKQSKKYNIYLYSRHLNSTINGI
                     IFIREDELPDAINQVDFIITCFSNHIETDNFINEFLLNIQSLRKTIVIDFTTSRIDCV
                     EKFKKTVEIKGGYYIEAPFTGGKLGSNSGQLSIFLHIDEGVNYNKKELMELLKLISKK
                     IYFFEKSTEPTKFKLIYNSWGAYLLYSIKLFNPLQYDFSPKSLEVANTIVCNDGWMSL
                     VCNSKLEQINDQDFDDIHFRVEYMVKDLEYANFSVFHDEVKEINYLLQQYGDCLVTDS
                     GKDYTVIGKYDNL"
     gene            1961..2683
                     /locus_tag="ACL8JK_001269"
     CDS             1961..2683
                     /locus_tag="ACL8JK_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGS1786147.1"
                     /translation="MITYRNDLLSKELDILISFFKKCEVGKISLVITGSLARGNPRIK
                     DGKLESDIDILVIVDSIQQLISIKKTLEGRFHFVHKISLIFCLKERINRSRYRGIINS
                     IRSVDNLLVDNLHIKNQIIEALDSPTNIVEQTRSMIQEFCYYSSKYLISKNNYLELKL
                     EKYWKEIATLNHIDKKIKHLDFERIFAVLKEHKIQILDSSEYFFQNVKTSENIYLEMR
                     DLVSLENQGLDFEHCILSLGER"
     gene            2680..3210
                     /locus_tag="ACL8JK_001270"
     CDS             2680..3210
                     /locus_tag="ACL8JK_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786148.1"
                     /translation="MIINTLGPTATDCFYAINRIKLKVDVIVLYDSFDSIVNCFDKLK
                     GQYILLPVAFESSIKNYSWKDFNFEYHKRIEIVDSFHSFTKGMVLIENCNYKINRAII
                     QPATEILMLNYLKKKSMDLRIDFTHSKVMANKKFLEEGYRFSIVSQETIINNDDIIIC
                     ETFSPEMIWCLYRVKG"
     gene            3214..4308
                     /locus_tag="ACL8JK_001271"
     CDS             3214..4308
                     /locus_tag="ACL8JK_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786149.1"
                     /translation="MFSEIIKKYDIVTLKDSGFLRGDWFIGSALMAHDYESLKEGIYF
                     YPQETIWTRILDLEYINPYWEIYNQTYNFLLVNKQDSLAMNFLTSLLREIEVISSKTL
                     DFVVITSNEHLIRNLIDRDYYIITKEIPFFIENSKVGNYFKIFVKNGGQFIPIIDCTE
                     FKIQSKKYFEININKFYLKLLDYFLHGEIPEKFKFFGNTSNFNIESLFLEFIDSQENI
                     RVVSLLDCLIQLSSKNIEISGNYKGHTVKKILKKFALYSVITKLDITKVNHLLRNDYI
                     YFLMKEIDNITKKYPKLIQKYPRDILSDRYGITNEVYRYLIGENLHIKINHKLDEVRY
                     FTDIPFIDTSLSIEEFDKIVSKILKIKVGG"
     gene            4311..4982
                     /locus_tag="ACL8JK_001272"
     CDS             4311..4982
                     /locus_tag="ACL8JK_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786150.1"
                     /translation="MIRLPNKFKGNNITLEVKLNKAVDASVLYPDVKSLDQELYRQLQ
                     SVESFYLTFSDMYSEINENNEILYTEIIFKIPLCIGEDYFNFPVVSYVSNPYSLIRGF
                     YLGFHKELDCNYVFDDAELHFFREGICEFNFEFKNQNSIITAELPREYNYPLILFNNS
                     NLVNQYGKYTLLDIDKYKLESRKIFEFPEISIGNFLGSEAKSNRVIFSQDKFQINGIK
                     NMEVN"
     gene            4984..6012
                     /gene="galE"
                     /locus_tag="ACL8JK_001273"
     CDS             4984..6012
                     /gene="galE"
                     /locus_tag="ACL8JK_001273"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGS1786151.1"
                     /translation="MKSLLITGGAGYIGSHTVLDLLDNNYEVTIIDDLSNSKKKVIES
                     IKQISKKSRNLHFYKIDLKNEEKLENVFKRHNFDGVIHFSGYKAVGESVVEPLKYYEN
                     NLLSTINILKLMKKYKVFNFVFSSSATVYESTPIMPFYETNPLKASNPYGRTKQYIEV
                     LLNDLFISNSNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLPYLN
                     IFGVDYSTPDGTCIRDYVHVNDLAYGHRKALEYIFNTDEGLYEVINLGSGVGFSVFEI
                     LHSLESVIGSYIPYKITSRRAGDMDVSIADISKAEELLGWKPRYDIMKMCQDTWKWQQ
                     KHPNGYDD"
     gene            6036..7280
                     /locus_tag="ACL8JK_001274"
     CDS             6036..7280
                     /locus_tag="ACL8JK_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit family protein"
                     /protein_id="HGS1786152.1"
                     /translation="MHIVLFRYSARVVKLKYLYNRNVVIIAPEVQRKKYEDYLAEGNN
                     LPKVIFLEDFILPNIILEIRRISQNTEVESITTLSEEDMDIVGFLNDHFVEKNTHSVS
                     NLLFKDKYFMRSFLVGVVNQPYFRLLESENDLRVFWNNCKSSAAILKPRNEAGSNGIK
                     KVYPNEKIDSVYFEKNYIIEEYIDIDNMITCDGYSIGSEIKRFYVHEYEELLFNTLSS
                     SGYYLVRTSSLYNDSEKIEYIEKALEECRKVLNVFSINSEITPFHFEWFLELSTGKIV
                     FCEVGKRFGGGDIPQLIEDSHGVDVIKEYWDILTNSQGLKKINFSKVISRPANISATF
                     ALYRKQGKVIEVPDEKELAWAKKVYIFIKPNTYYKVSENVVENSMLVQFNCKNSCEFE
                     KRLDELKHISQKFKYVITDSGE"
     gene            7282..8493
                     /locus_tag="ACL8JK_001275"
                     /pseudo
     CDS             7282..8493
                     /locus_tag="ACL8JK_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428251.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            9173..9394
                     /locus_tag="ACL8JK_001276"
     CDS             9173..9394
                     /locus_tag="ACL8JK_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS1786153.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            9840..10164
                     /locus_tag="ACL8JK_001277"
                     /pseudo
     CDS             9840..10164
                     /locus_tag="ACL8JK_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            10292..11521
                     /locus_tag="ACL8JK_001278"
     CDS             10292..11521
                     /locus_tag="ACL8JK_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGS1786154.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            11541..14237
                     /gene="ppc"
                     /locus_tag="ACL8JK_001279"
     CDS             11541..14237
                     /gene="ppc"
                     /locus_tag="ACL8JK_001279"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HGS1786155.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDCIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    14320..14537
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            14650..15654
                     /gene="trpX"
                     /locus_tag="ACL8JK_001280"
     CDS             14650..15654
                     /gene="trpX"
                     /locus_tag="ACL8JK_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1786156.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATSAAQGLASATKDLPVIMAAITDPIGANLVKGLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            15723..16589
                     /locus_tag="ACL8JK_001281"
     CDS             15723..16589
                     /locus_tag="ACL8JK_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1786157.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            16586..17344
                     /locus_tag="ACL8JK_001282"
     CDS             16586..17344
                     /locus_tag="ACL8JK_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1786158.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            17434..19194
                     /gene="dnaG"
                     /locus_tag="ACL8JK_001283"
     CDS             17434..19194
                     /gene="dnaG"
                     /locus_tag="ACL8JK_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGS1786159.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KSASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            19197..20306
                     /gene="rpoD"
                     /locus_tag="ACL8JK_001284"
     CDS             19197..20306
                     /gene="rpoD"
                     /locus_tag="ACL8JK_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGS1786160.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            20320..20649
                     /locus_tag="ACL8JK_001285"
     CDS             20320..20649
                     /locus_tag="ACL8JK_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGS1786161.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            20764..21807
                     /gene="cpoA"
                     /locus_tag="ACL8JK_001286"
     CDS             20764..21807
                     /gene="cpoA"
                     /locus_tag="ACL8JK_001286"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HGS1786162.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            21823..23148
                     /locus_tag="ACL8JK_001287"
     CDS             21823..23148
                     /locus_tag="ACL8JK_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS1786163.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            23179..23355
                     /locus_tag="ACL8JK_001288"
     CDS             23179..23355
                     /locus_tag="ACL8JK_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGS1786164.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            23414..23548
                     /locus_tag="ACL8JK_001289"
     CDS             23414..23548
                     /locus_tag="ACL8JK_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGS1786165.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            23612..24922
                     /gene="obgE"
                     /locus_tag="ACL8JK_001290"
     CDS             23612..24922
                     /gene="obgE"
                     /locus_tag="ACL8JK_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGS1786166.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            24932..25090
                     /locus_tag="ACL8JK_001291"
     CDS             24932..25090
                     /locus_tag="ACL8JK_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786167.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            26198..27457
                     /locus_tag="ACL8JK_001292"
     CDS             26198..27457
                     /locus_tag="ACL8JK_001292"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGS1786168.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            27473..28024
                     /locus_tag="ACL8JK_001293"
     CDS             27473..28024
                     /locus_tag="ACL8JK_001293"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1786169.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            28017..29294
                     /gene="spxR"
                     /locus_tag="ACL8JK_001294"
     CDS             28017..29294
                     /gene="spxR"
                     /locus_tag="ACL8JK_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HGS1786170.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATTINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            29310..30170
                     /locus_tag="ACL8JK_001295"
     CDS             29310..30170
                     /locus_tag="ACL8JK_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HGS1786171.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKSGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVIGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            30393..>30631
                     /locus_tag="ACL8JK_001296"
     CDS             30393..>30631
                     /locus_tag="ACL8JK_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786172.1"
                     /translation="MSQSIVPVEIPQYCRFDSKKRNGILFNVRIANLKFTFFRLDSLR
                     NKTWYSSSMNDEASKQLTDARFKRFVGVQRTTFEE"
BASE COUNT         9859 a         4768 c         6395 g         9609 t
ORIGIN      
        1 atctgtctat agttaaaact acaagttcat cggagttgat aaggttttat tgagactctt
       61 gattataaaa cgttagatgg taaggaatca tttcatttat tgtttacaag tttatcaaaa
      121 tggctagtat agtgtaattt taacttgtct tctcctaaaa tatcgagaac ttgtatagct
      181 tgtttcattg tttcaatacc actacttaat tgacgtttaa attcatagta accggttgca
      241 tagagaaaaa ctgtctgttc ataaaagttt aattcattct ctgaacaatc cctttatctc
      301 attaattaaa taagagcaat tagaaaattc ttctttatct atgctgagaa tgaaacaatt
      361 tatagctagc tgagtgacaa tccgcttatt tgttttattt agagatgagt aaatataatt
      421 atttaacatt tctttagtta ataagaagta ggagttgtag ttaattgttc gtacacagtt
      481 acctaataaa ataatctcat aataacccca tttttcaact ttaaagagat aatctgctag
      541 ttgaagtaat tcatcatctg atggaatgat tcttgaatcc attgtgtgta aaatggattt
      601 taccattgtt ttttcaaaag aatctaaagt gtaatttgag gaatccgaaa gtagagattg
      661 tatattattg atgttttgta atgaatattg tttacggata tactgtatta agttggcaaa
      721 tgactcagtt tttgtatagt cttcatcgtg taaaataaga aactcatcca aagtaatgtg
      781 taatttgtct aaaatattga tcagtcggat acatgatatc tctgactctc cacgttcaaa
      841 tcgggatatt tgcgattttg aaagatgctc atcagcaaca gagcatagac tgatttgttt
      901 gcctttacga acttttctaa gtgtgatgcc aagttttgat ttcaaaattt ttcccaattt
      961 tgatgctagt gatggacatt atcattattg ttggtggtta aatcacttag gtgtacacct
     1021 aagtctttag attatctaaa gactatactt actagctaaa acatatttaa gttaaatcgt
     1081 aaaattttag agagtggtga gactttgaaa cataaaaaag tattaattat agggtatggt
     1141 ataatgactc ggggtatatt aaaaatcctg aaacagtcga aaaaatataa tatataccta
     1201 tatagtaggc atctaaattc aacaataaat ggaataatat ttattagaga agatgaatta
     1261 cctgatgcta taaatcaggt tgattttata atcacttgtt ttagtaatca tattgaaacg
     1321 gataatttca ttaatgagtt tttattaaat atacaatcac ttcgtaaaac catagtaatt
     1381 gattttacaa cctccaggat tgattgcgtt gaaaaattta aaaaaactgt tgaaattaaa
     1441 gggggatact atatagaggc tcctttcaca ggaggtaagt taggaagtaa tagtggtcaa
     1501 ctatcaattt ttttacatat tgatgaaggt gtaaactata ataaaaagga gttaatggaa
     1561 ttattaaaat taatttcaaa aaaaatatac ttttttgaaa agagtacgga accaacaaaa
     1621 ttcaagttaa tttataactc gtggggagcg tatttgcttt actctattaa gctattcaac
     1681 cctttacagt atgatttttc accaaagtct ctagaggtag cgaatacaat cgtatgtaat
     1741 gatggttgga tgagtttagt atgcaactcc aaattagaac agatcaatga tcaagatttt
     1801 gatgacatac actttagagt agaatatatg gtaaaagatt tagaatatgc taatttttca
     1861 gtctttcatg atgaagtgaa agaaataaat tatttattac agcaatatgg ggattgctta
     1921 gtaactgata gtggaaaaga ttatacggta ataggaaagt atgataactt ataggaatga
     1981 cttgctgtct aaagaattag atatactaat ttcatttttt aaaaaatgcg aagtaggaaa
     2041 aatttcactc gttattactg gttccttggc aagaggtaat ccaagaatca aggatgggaa
     2101 attagaatcg gatattgata ttctagttat agtagacagt attcagcaat taattagtat
     2161 aaaaaagact ttagagggaa ggtttcactt tgtacataaa atttctttga ttttttgttt
     2221 gaaggaaaga ataaatcgaa gtcgttatcg tggaattatt aatagtatta gaagtgtaga
     2281 taatctttta gtagataatc tgcatataaa aaatcaaata atagaagctt tagactcacc
     2341 taccaatatt gtggagcaga ctcgctctat gattcaggaa ttttgttatt attcatcaaa
     2401 atatttaatt tcaaagaata attatttgga attaaaacta gaaaagtatt ggaaggagat
     2461 tgcaacatta aatcatatcg ataaaaagat aaaacaccta gattttgaaa gaatatttgc
     2521 tgttttaaaa gaacacaaaa tacaaatttt ggattcaagt gaatattttt tccaaaatgt
     2581 aaaaacttct gagaatattt atttagagat gagggattta gtatctttgg aaaatcaagg
     2641 attagacttt gaacattgta ttttgagctt gggggaaaga tgataataaa tacattagga
     2701 ccaactgcaa cagattgttt ttatgcaata aatcgtataa aattaaaagt agatgtgatt
     2761 gtactgtatg atagttttga tagtatagtt aattgctttg ataaattaaa agggcaatat
     2821 atattattac ctgtagcttt cgagagtagt attaaaaatt atagttggaa agatttcaac
     2881 tttgaatatc ataagcggat tgaaattgtg gattcttttc actcttttac taagggaatg
     2941 gttctaatcg agaattgtaa ttataaaatt aatagggcga ttatccaacc tgcaactgag
     3001 attttgatgt taaactattt aaagaaaaaa agtatggatc tgaggataga ttttacccat
     3061 agtaaagtta tggcaaataa aaaatttctg gaagaaggtt atcgtttttc aatagtaagc
     3121 caagaaacga taattaataa tgatgatatt attatttgtg aaactttctc tccagaaatg
     3181 atttggtgct tatatagagt gaaaggatag aaaatgtttt ctgaaattat taagaaatat
     3241 gatattgtta cactgaaaga tagtggtttt ttgagaggtg attggttcat aggttcagcg
     3301 ttaatggctc atgactatga aagccttaag gaagggatat atttctatcc ccaggaaaca
     3361 atttggacaa gaatcttgga tttagaatat ataaatccgt attgggaaat atataatcaa
     3421 acttataatt tcttattagt taataaacaa gattcattag caatgaattt tttaactagt
     3481 cttctaagag aaatagaagt tatttcgtct aaaacattag attttgttgt tattacttca
     3541 aacgaacacc taattaggaa tttaattgat agagactatt atattattac aaaagagatt
     3601 ccatttttta ttgaaaactc aaaagttgga aattatttta aaatttttgt gaaaaatgga
     3661 ggacagttta ttcctataat tgactgtacg gaatttaaga ttcagtctaa gaaatatttt
     3721 gagataaata ttaataaatt ctacctgaaa cttttggatt actttcttca tggagagatt
     3781 ccagaaaaat ttaaattttt tggaaatacc tctaatttca atatagaaag cttgtttcta
     3841 gaatttattg atagccaaga aaatattcga gtagtttcct tgttggattg tcttattcaa
     3901 ttatcctcta aaaatattga aatttcagga aattataaag ggcacacagt gaaaaaaata
     3961 ctaaaaaaat tcgctttata ctcagtaatt accaaacttg atataacgaa agtaaatcat
     4021 ttattgagaa atgattatat ctacttttta atgaaggaaa ttgacaatat tactaaaaaa
     4081 tatccaaagt taattcaaaa gtaccctaga gatatcttga gtgataggta tggaataaca
     4141 aatgaagtat atagatactt aatcggagag aatttacata taaaaattaa tcataaatta
     4201 gatgaggtta gatattttac agatattcca tttattgata cttcactttc tattgaagag
     4261 tttgacaaaa tagtttctaa aatattaaaa attaaagtgg gagggtaact atgataagat
     4321 taccaaataa atttaaaggt aataatataa ctctagaagt taaactaaat aaagcagttg
     4381 atgctagtgt attataccca gatgttaagt ctctagatca agaattgtat cgacaactac
     4441 aatcagtaga atcattctat cttacctttt ctgatatgta ttcagaaatt aatgaaaata
     4501 atgaaatctt atatacagaa ataatcttta agatacctct ttgtattgga gaagattatt
     4561 ttaattttcc ggttgtatca tatgtttcaa atccctattc gttaataaga ggattttatc
     4621 taggttttca taaggaattg gactgtaact atgtatttga tgatgcagag cttcattttt
     4681 ttagggaagg gatttgtgaa tttaacttcg aatttaaaaa tcaaaattca atcattacag
     4741 cagaattacc aagggagtat aactatccct tgatcttgtt taataattcc aatctggtta
     4801 atcaatatgg aaaatatact ttgttagaca tagacaaata taaattagag tctagaaaga
     4861 tttttgaatt tccagaaatt tctatcggta actttcttgg aagtgaagca aaatcaaata
     4921 gggtaatttt tagccaagat aaatttcaaa ttaatggcat aaagaatatg gaggtaaatt
     4981 agcatgaaat cattattaat aacaggtgga gcaggataca taggatcaca tacagttttg
     5041 gacttgttag ataataatta tgaagtaaca atcattgatg atttgagtaa ctctaagaaa
     5101 aaagttattg agtctattaa gcagatatcc aagaagagta gaaatcttca tttttataaa
     5161 attgatttaa aaaatgaaga aaaattggaa aatgttttta agagacataa ttttgatgga
     5221 gtaattcatt tttcagggta taaagctgtt ggagaatccg tggttgaacc attgaagtat
     5281 tatgaaaata atttattatc aactataaat attttaaaac taatgaaaaa atataaggta
     5341 tttaattttg tgtttagttc atcagctact gtatacgaaa gtactcctat catgccattc
     5401 tatgagacta atccattaaa agcttcaaac ccgtatggga gaacaaaaca gtatatagaa
     5461 gtacttttaa atgatttgtt tatttcgaat tcaaattgga aaattgtttg tctgaggtat
     5521 tttaatccat tgggtgcaca tgaaagtggt gatttaggag aggatccaaa tggaattccg
     5581 aataatcttg ttccttacat tacacaagtt gcaattggaa aattaccata tttaaatata
     5641 ttcggagttg attacagtac tcctgatggg acttgtataa gggactatgt tcacgttaac
     5701 gatttagcat acggacacag aaaagcatta gagtatattt ttaatacaga tgaaggttta
     5761 tatgaagtaa tcaatttagg aagtggtgtt ggttttagtg tatttgaaat cctacacagc
     5821 ttagagagtg tcataggctc gtatattcca tataagataa cttcaaggag agcaggagat
     5881 atggacgttt caattgcaga tatttcaaaa gcagaagagc tactgggatg gaagccaagg
     5941 tatgatatta tgaaaatgtg ccaagatacg tggaaatggc aacagaaaca tccaaatgga
     6001 tatgatgact aataattgaa aggattggga ttaacatgca tatagtatta tttagatatt
     6061 ctgcacgggt tgttaaacta aaatatctgt ataacagaaa tgtagtaatt attgcacctg
     6121 aggttcaaag aaaaaaatat gaagattatc tagctgaagg aaataatcta cctaaggtca
     6181 tttttttaga agattttatt ctaccaaata tcatcttaga aattagaagg ataagtcaaa
     6241 atacagaagt tgagagtatt acaaccttga gtgaggaaga catggatata gtaggttttt
     6301 tgaatgatca ttttgtagaa aaaaatactc actctgtgtc taatttatta tttaaagaca
     6361 aatacttcat gcgttcattt ttagttggag tagtaaatca accgtatttt aggcttttag
     6421 aatcagaaaa tgatttacgt gttttttgga ataattgtaa atcttctgct gcaattttaa
     6481 aacctagaaa tgaagcagga agtaatggaa taaaaaaagt ttaccctaac gagaaaattg
     6541 attcagtgta ttttgaaaaa aactatatta tagaggaata cattgatatc gataacatga
     6601 taacatgtga tggttattca attggaagtg agattaagcg attttatgtt cacgaatatg
     6661 aggaactatt gttcaatacc ttaagttcta gtggatatta tcttgtaagg actagttcgt
     6721 tatataatga tagtgaaaaa attgaataca tagaaaaagc attggaagaa tgtcgcaaag
     6781 ttttgaatgt tttttctatc aattctgaaa taaccccttt tcattttgaa tggttccttg
     6841 aattatcaac tggtaaaata gtcttttgtg aagttggaaa aagatttgga gggggagata
     6901 ttccccagtt aattgaggat agtcatggag ttgatgtaat taaagaatat tgggatattt
     6961 tgactaattc acaaggattg aaaaaaataa atttttctaa agtgatttct agacctgcta
     7021 atatctcagc aacgtttgct ttatatagaa agcaaggtaa ggttatcgag gtacctgatg
     7081 aaaaagaatt ggcttgggca aaaaaagtgt acatatttat taaaccaaat acttactata
     7141 aagtatctga aaatgtagtc gaaaattcaa tgttggtcca atttaattgc aaaaatagtt
     7201 gtgaatttga gaaaaggtta gatgaactta agcacatatc acaaaagttt aaatatgtga
     7261 ttactgattc gggagaataa aatgattaga gaagaacatc acaatattct atccattgta
     7321 gctagtagga tgatatctcg aatcggagat atcatgtttg atttcgccaa taataccttt
     7381 cttgctggtc ttaatccaac atctctatca gtggttgcaa tttatcaatc attagaaagt
     7441 atgataggtg ttctatttaa tttatttggt ggagttattg cagatagttt caagcggaaa
     7501 aaaattatta ttactacaaa tatcttatgt ggtattgctt gcataactct ttcatttata
     7561 tcccaagaaa aatggttggt ttatgcgata gtcataacaa atgtcatttt ggcttttatg
     7621 agtgcttttt cagggccatc atacaaagct tttacgaaag aaattgtaaa aaaggacagt
     7681 atatcataac ttaattcatt gctagaaaca acaagtactg tgattaaagt aacaattcct
     7741 atgattgcaa ttttcttata taagttactt ggaatacatg gtgtgttatt actagatgga
     7801 ttatcgtttt taattgctgc ctcactaatt ttcttcatta ctcctgtaaa tgaggaggtg
     7861 gatacaaaag agaatatgac gataagagga atctttgatg atttaaaaat aggatttacg
     7921 tatgtatata gtcataaaca aattctcact ataattgccc tttcagcact tgttaacttt
     7981 ttcctagcag cctataattt gttgctgcca tacagtaatc aaatgtttgg aagtatttca
     8041 agtgggctat atggaacctt tttaacagcc gaagcgattg gtggctttat tggtgcgata
     8101 ttaagtggat ttatcaataa atccttgtca agcaaacgtt taatgctctt tttagcatat
     8161 tcaggtttga tgttaatgct aacagcgccg atctattata tgttccgcaa cgtcattatt
     8221 ttagccttta ctccagcatt atttagtcta tttctttcca tttttaatat ccaatttttc
     8281 tctattgttc aaagagacgt agataatgag tttcttggca gagtatttgg aatcatcttt
     8341 acggtagcta ttctttttat gccactaggt actgtttttt tctcagtagt tttaaatcct
     8401 aacaatactt ttaatttttt tattattggt gtatctatta cgatattatc gctaatattt
     8461 agcacgctat tgaagaggta tgatagaagt tgatagatga taaaaaatag ctgatataga
     8521 gaatttagag cgcctttgga atatattttt ggaatttaat caatcacagt tgaatgtgaa
     8581 gggcaatcct ttttagaaga atacaatcaa gataccatta tgctatttct ttagttcagt
     8641 taaaatattg agaagtatta cttttattga aaaagcatca caaaggactc caattaattt
     8701 ttaatgattt ttctaatcta attttgtggt tattgacaaa taaagtctag ttaattgctt
     8761 tgaaatccat ggagtggtct atatacatct gttaatgcaa cggaaaattt tattgataag
     8821 tagggggtgg ctattattca acttttaggt tctgaaagta agagattcac attagaaata
     8881 tcatgttgac catttttcaa tttgctggtt agtagtaatc tggacatcat taatcccttc
     8941 cttaacaaaa ttatgtgact tttgttaccg gattactgct gattttttaa tagtttataa
     9001 catctttaga cggttaatag attttgaccg tctttcttaa tattgtctta cctataatag
     9061 atatgcttat gagatatgtt taataaatta attttagttc aaaatgtcca gtttggacac
     9121 tttgaatgat ttcttagttt tatatattat acttttctca ggagaaagct agatgtacag
     9181 acgtttgaga gatttgaggg aagatcacga tttgacccaa aaacaaatag ctaaaatact
     9241 ttcgtttaca aactcagctt atgctaaaat tgaacggggt gagcatacgt taacagcaga
     9301 tgtattggta actctctcaa acttttacga tgtcagtaca gactacctat tggaattgac
     9361 agattttcct gataaaattc gctttagaaa ataatctcct caatttcata gagtgtgaaa
     9421 atgaggagat tttttatttg ttctttgaaa attaaatagt ccaaaatggt actttcctca
     9481 tttgtggagc aaatttgaat ggctcgccat gataagagcg attttaaaac catcaataaa
     9541 atagagcgat actttatatg ccatgataca aatgatatac aatgatactt ctgaccgttc
     9601 aggctgccat cgtaaaagag cagcaagtga aattcttatg atgacttcat cagtcatgcc
     9661 acgttaaatg tgtgagtttg ttagagaaac gcaattaatc ctcaaaaggt tccccgaacc
     9721 ttttgagttc cacagacgca tcacgtggag tgtgtaagct tgttgctaaa agcgtaaaaa
     9781 ccttggaacg aaaggaataa tagacttcct gcgaaacaaa aatacaatac aataaaacta
     9841 tggatgatga agcaagtaaa caattaagcg atagccgttt caagagcctt gtaggtgttc
     9901 agcgcacgag atgttagctg tgtcaaaaac agcttatcaa cgcaacgtaa acgcgcaaaa
     9961 ggtggacgaa aaaccaaatt aagcctagac gatctcctca tggtaactat tcaatacatg
    10021 cgagaatagc gcacttatga acaaattgcg gctgattttg gcattcacga aagcaactta
    10081 atccgtcgga gccaatgggt tgaagtaact cttgttcaaa atggttttac gatttcaaat
    10141 tctgccctaa ttatgaaaaa cagtaaaatt cgaaggattg taaggtaaga gtttttttct
    10201 ttctgaaaaa atggtataat agcaatcaaa actagaaaat aaaacggaat ttggaacaga
    10261 tttgtctgta tcctagtaga gtggtgatgc tatgaagatt agtaagaggc acttattaaa
    10321 ttattccatc ttgattccct acttgctttt atctattttg ggcttgattg tggtctattc
    10381 gaccaccagt gctattttaa ttgaagaagg caagagcgcc ttgcagttgg ttcgaaacca
    10441 aggaatcttt tggattgtta gtttgatact gattgcctta atttataaat tgagactaga
    10501 ttttttgaga aatgagcgac taatcatttt agttatatta atagaaatgc ttttattgtt
    10561 cttggctcgt tttattggta tttccgtaaa cggggcatac ggttggattt cggttgcagg
    10621 aataactatt cagccagctg agtacttaaa aatcattatt atttggtatt tagctcaccg
    10681 attctccaaa cagcaagaag aaatagctac ttatgatttt caagttttga ctcaaaatca
    10741 atggcttccc cgtgctttta atgattggcg attcgttctc ctagttctga ttggaagttt
    10801 gggaattttc cctgatttag gaaatgcgac tattttagtc ttggtttcct tgattatgta
    10861 tacagttagt ggaatcgctt atcgctggtt ttcaaccatt ctggcgctcg tatctgccgc
    10921 ttctgtcttt gtcttgacca ctatcagcct aatcggtgtt gagacctttt caaaaattcc
    10981 agtatttggc tatgtagcca agcgctttag tgcctttttt aatccttttg ccgatcgtgc
    11041 tgatgcaggt caccagttag ctaattctta ttttgccatg gtcaatggcg gttggtttgg
    11101 tctaggtctt ggaaactcga ttgaaaaacg aggttatttg ccagaagctc atacagactt
    11161 tgtcttttct atcgtgattg aagaatttgg ctttgttggt gccagtctta ttttagctct
    11221 cttgtttttc atgattttgc ggattatctt ggtcggtatt cgagcggaga atcctttcaa
    11281 tgccatggtt gcactcggtg tcggagggat gatgttggtt caggtatttg tcaatatcgg
    11341 agggatttcg ggcttgattc catctacagg agtaaccttc cccttcttat cccagggtgg
    11401 aaatagtctt ctagtcttat cagtggcagt agcctttgtc ttaaatattg atgccagtga
    11461 aaaacgcgct aagttgtacc gagaattgga aaatcaacca atgaaccttc tgttgaagta
    11521 ggataaagaa aggatagttt atgtctcttc aaaaattaga aaattatagt aataaaagtg
    11581 ttgtgcaaga agaagtcttg attctaacag aattactgga agatattact aaaaatatgc
    11641 ttgccccaga gacctttgaa aaaataatac agttgaaaga attatcaacg caggaagatt
    11701 atcaaggtct aaaccgtcta gtgactagct tatcaaatga tgaaatggtc tatatttcac
    11761 gctatttctc tatcttgcct cttttgatta atatttcaga ggatgtggat ttagcttatg
    11821 aaatcaatca tcaaaataat attgatcagg actatttagg taaattatct acaacgatta
    11881 aattggtagc agaaaaggaa aatgccgttg agatcctaga acacttgaat gttgtccctg
    11941 ttttgacagc ccatccaaca caagtgcaac gcaaaagtat gttggattta acaaatcata
    12001 ttcatagtct tttgcgtaaa taccgtgatg ttaagttggg gttgatcaat aaagataaat
    12061 ggtacaatga tttgcgtcgt tacatcgaaa ttatcatgca gacagacatg attcgtgaga
    12121 aaaaattaaa agtgactaac gaaatcacga atgctatgga atattataac agctcctttt
    12181 tgaaagctgt acctcatttg acgacggagt ataagcgctt agcgcaagcg catggtctga
    12241 atttaaaaca ggctaaacca atcaccatgg gtatgtggat aggtggtgac cgtgatggaa
    12301 atccatttgt tacagcaaag accttgaagc agtctgcact cactcagtgt gaagtcatca
    12361 tgaactacta tgataaaaag atttaccaac tttatcgtga attttctctt tcaactagca
    12421 ttgtcaacgt cagcaagcaa gtcagagaaa tggctcgtca atccaaggat aactcgattt
    12481 accgcgaaaa agagctttac cgtcgtgcct tgtttgatat tcaatcaaaa attcaggcaa
    12541 ctaaaaccta tctgattgag gatgaagaag ttgggactcg ttatgaaacc gccaatgatt
    12601 tctacaagga tttgattgcc attcgagatt ctctactaga aaataagggt gagtccttga
    12661 tttcaggtga ttttgtggaa ttattgcagg cagtagagat atttggtttt tacttagcgt
    12721 caattgatat gcgacaagac tctagcgtct atgaagcctg tgtggcagaa ctcttgaaat
    12781 cagcaggaat tcattctcgt tatagcgagt tgagcgaaga agaaaagtgt gaccttctct
    12841 tgaaagaatt agaagaagat ccccgaattc tttctgcgac tcacgcagaa aaatcagaat
    12901 tattagcaaa agaattagct atttttaaga cggctcgtgt tttgaaagat aagttgggag
    12961 atgatgtcat ccgtcagacc atcatttcac atgcaaccag cctttctgat atgctagaat
    13021 tagctattct gttaaaagag gtaggactgg tggatacgga aagggcgcgt gttcagattg
    13081 ttcccctttt tgaaacaatt gaagacttgg atcattcaga ggaaacaatg agaaaatatc
    13141 tttctcttag ccttgccaaa aaatggattg actcacgaaa taactaccaa gaaatcatgc
    13201 ttggctactc tgacagtaat aaagatggcg gttacttgtc atcatgttgg accctctaca
    13261 aggctcaaca acaattgact gctattggag atgaatttgg cgttaaggtt accttcttcc
    13321 atggtcgtgg tggtactgtc ggtcgtggtg gtgggccaac ctatgaagcc attacatctc
    13381 aaccgctcaa gtctatcaag gattgtatcc gcttgacgga gcagggtgaa gtaattggga
    13441 ataaatacgg taacaaagac gccgcttact ataaccttga aatgctagta tcggcagcta
    13501 ttaaccgtat gattactcag aagaagagcg ataccaatac cccaaatcgt tatgaagcca
    13561 ttatggatca agtagtggac cgtagttacg atatctaccg tgatttggtc tttggtaatg
    13621 agcatttcta tgattatttc ttcgagtcaa gtccaatcaa ggctatttca agttttaata
    13681 ttggttctcg tccagccgct cgtaagacta ttactgaaat cggtggtttg cgtgccatcc
    13741 cttgggtatt ctcatggtca cagagtcgtg ttatgttccc tggatggtac ggggttggtt
    13801 caagcttcaa ggaatttatc aataaaaatc cagagaatat tgctatctta cgagatatgt
    13861 accaaaattg gcctttcttc caatcgcttc tttcaaatgt tgatatggtt ttgtcaaaat
    13921 caaatatgaa tattgctttt gaatatgcta aactttgtga agacgagcaa gttaaggcca
    13981 tctatgagac tattttaaat gaatggcaag ttactaagaa cgttatcttg gctattgaag
    14041 gacatgacga actcttagct gacaatccat atctaaaagc tagtctggat taccgtatgc
    14101 cttactttaa tattctcaac tatattcagt tagagttgat taaacgccaa cgtcgtggag
    14161 aattgtccag tgatcaagaa cgattgattc atatcaccat caacggaatt gcgacaggat
    14221 tgcgtaattc aggttgataa ttttcaagag tgaatgctaa aagtgaatat caaaaaaatt
    14281 ctaatagact attgacaagt agtttaaaaa tgatataatt taaccattca gaaaagtaat
    14341 catacaaact ttttagagag tctgtggtag ctgaaaacag ataagtggcg atgatgaaaa
    14401 ttgggctgaa tgctatttag aatttgaaat tataaaaatt cggtaagcac accttacagt
    14461 gcatctcgtt attgcgagac tgagcgatag ggaaattccc tataattgag gtggtaccgc
    14521 gcatcgacgt ccttacacaa gttttttgtg tgaggatttt tttgatggag gttagtatgg
    14581 aaagaaaacg atggcgtcgc ttgtttagat aagtgaaata tgttaaagga aataaaaagg
    14641 agaaacagaa tgaaaaataa acgtttaatt ggaattattg ctgcattagc agtcttagta
    14701 gcaggaagct tgatttattc ttcaatgaat aaatcagaag ctcagaataa taaggatgag
    14761 aagaaaataa ccaagattgg tgtgcttcaa tttgtgagcc atccatccct tgatttgatt
    14821 tataaaggga tccaagatgg acttgcagaa gaaggatata aagatgatca agttaaaatt
    14881 gattttatga actcagaagg tgaccaaagt aaggttgcga caatgagtaa acaattggtt
    14941 gcaaatggga atgaccttgt ggttggtatc gcaacatcag cagcccaagg gttggctagt
    15001 gcaacaaaag acctaccagt tatcatggcc gctattacag acccaattgg tgctaacttg
    15061 gttaaaggtt tgaaaaaacc aggtggcaac gttacagggg tatctgacca caatccagct
    15121 caacaacaaa ttgaactcat caaggctctg acaccgaatg tgaaaacaat cggagctctt
    15181 tactcaagta gcgaagacaa ttcaaaaaca caggtcgaag aatttaaggc ttatgctgaa
    15241 aaagcaggtc tgacagtgga aacatttgca gttccttcaa caaatgaaat tgcctcaact
    15301 gtcactgtta tgactagcaa ggtagatgct atttgggttc caattgataa caccattgca
    15361 tcaggatttc caacggttgt ctctagcaat caaagttcta agaaaccaat ttatcccagt
    15421 gcgacagcta tggtagaagt aggtggtttg gcatcagttg taattgacca acatgacctt
    15481 ggtgtggcaa caggtaaaat gattgtgcaa gtcttgaaag gtgcaaaacc agccgatacc
    15541 ccagtcaatg tcttttcaac tggtaagtca gtcatcaata aaaaaatagc acaagaacta
    15601 ggtattacta ttcctgagtc tgttctcaaa gaagcaggac aagtcatcga ataaataagg
    15661 tagggaggag gagactcttc ccatttttta aaaagatgaa tatagaaagg attaaataaa
    15721 atatgattgt ttccattatt tctcaaggat ttgtctgggc tattctaggt ctgggaatct
    15781 ttatgacatt taggatttta aactttccag atatgacgac agaaggttcc ttccctcttg
    15841 ggggagctgt tgctgtcact ttgataacca aaggcgtgaa cccattttta gcgacacttg
    15901 ttgctgtagg agcaggttgt ttggctggaa tggcagcagg ccttctttat acaaaaggga
    15961 agatcccaac cttgctctca gggattttgg tgatgacttc ttgtcactca atcatgctct
    16021 tgattatggg acgtgcgaat ttaggcctgc ttggaaccaa gcaaattcag gatgttttgc
    16081 cttttgattc ggatttgaat caactcttga caggtctcat ctttgtgagt attgttattg
    16141 ctctcatgct ctttttcttg gacactaaac tcggacaagc ctatattgct acaggggata
    16201 atcctgatat ggctagaagt ttcgggattc atactggacg catggagctc atgggcttgg
    16261 tcttatcaaa tggtgtgatt gcccttgcag gtgccctcat tgctcagcaa gaaggttatg
    16321 ccgatgtgtc tcgagggatc ggggttatcg ttgtggggct tgcaagtttg attattggag
    16381 aagttatttt caagagtttg agcttggcag agcgtttggt tactatcgtt gtaggttcta
    16441 tcgcttatca atttttagtg tgggcagtta tcgcacttgg ctttaataca agttaccttc
    16501 gtttatacag tgccttgatt ttagcagtct gcctcatgat tccaacattt aagcaaacaa
    16561 tcttgaaagg agccaagtta agcaaatgac agcaattgta gaattaaaaa atgcaaccaa
    16621 aatcgttaaa aatggctttg atgaagaaaa gattatttta aatgatgttt ccttagaaat
    16681 ttttgaacgg gactttatca cgattttggg cggaaatggt gctggaaaat caactctctt
    16741 taacactata gcagggacct tatcactaac tagtggaact atccgtattt taggtgaaga
    16801 tctcactaag ttttcacccg agaagcgtgc caagtacctg tctcgtgtct tccaagatcc
    16861 aaagatgggg acagctcccc gtatgacggt cgctgaaaat cttttaatcg ccaagtttcg
    16921 tggtgaaaag cgtggattgt taccacgacg cttgactagc tataaggatg aatttcaggc
    16981 aaccattgaa aaagtaggaa atggtcttga gaaacacttg aatacaccga ttgagttctt
    17041 atcaggtgga caaagacagg ctttgagtct cttgatggca accttgaagc gacctgaatt
    17101 actcctgtta gatgagcata ctgctgccct ggatccaaag actagtgttg ctttgatgga
    17161 attgacagat gaatttgtta agaaagatca gctaacagcc cttatgatta ctcatcatat
    17221 ggaagatgct ctcaaatacg gcaatcgctt gattgtcatg aaagaaggac gaattatcca
    17281 agatttaaac caagaagaaa aagcaaaaat gaaaatctct gattattatc aactctttga
    17341 ataaagtagg gaaaatgagt gaaatggttt actttttttc tgaaataaag tatactatat
    17401 aaagtaaact atgataacat ggaggtattg tgtatggttg acaaacaagt cattgaagaa
    17461 atcaaaaaca atgccaacat tgtggaagtc ataggagatg tgatttcttt acaaaaggca
    17521 ggacggaact atctagggct ctgtcctttt catggtgaaa aaacaccatc tttcaatgtt
    17581 gtagaggaca agcagtttta tcactgtttc ggttgtggtc gctcaggtga tgtctttaag
    17641 ttcatcgagg agtaccaagg ggttcccttt atagaagcag tccaaatctt aggtcagcgt
    17701 gttggaattg aggttgaaaa accgctttat agtgagcaga agtcagcctc acctcaccaa
    17761 gctctttatg atatgcacga agatgcagcc aaattttacc atgctattct catgacaacg
    17821 actatgggcg aagaggccag aaattacctt tatcagcggg ggttgacaga tgaagtgctt
    17881 aaacattttt ggattggttt agcacctcca gaacgaaact atctctatca acgtttgtct
    17941 gatcagtatc gtgaagagga tttactggat tcaggcctgt tttatctctc ggatgccaat
    18001 caatttgtag acacctttca caatcgcatt atgtttcccc tgacaaatga ccaaggaaag
    18061 gtcattgcct tctcaggtcg tatctggcaa aaaacggatt cacaaacttc taagtataaa
    18121 aacagccgat cgactgcaat ttttaacaaa agttacgaat tatatcatat ggatagggca
    18181 aaaagatctt ctggaaaagc tagtgagatt tacctgatgg aaggattcat ggatgttatt
    18241 gcagcctatc gggctggaat cgaaaatgct gtggcgtcga tgggaacagc cttgagtcga
    18301 gagcatgttg agcatctgaa aaggttaacc aagaaattgg ttcttgttta cgatggagat
    18361 aaggctgggc aagccgcgac attgaaagca ttggatgaaa ttggtgatat gcctgtgcaa
    18421 atcgtcagca tgcctgataa cttggatcct gatgagtatc tacaaaaaaa tggtccagaa
    18481 gacttggcct atctattaac gaaaactcgt attagtccga ttgagttcta cattcatcag
    18541 tacaaacctg aaaacagtga aaatctgcag gctcagattg agtttcttga aaaaatagct
    18601 cccttgattg ttcaagaaaa gtccatcgct gctcaaaaca gctatattca tattttagct
    18661 gacagtctgg cgtcctttga ttatacccag attgagcaga ttgttaatga gagtcgtcag
    18721 gtgcaaaggc agaatcgcat ggaaggaatt tccagaccga cgccaatcac catgcctgtc
    18781 accaagcagt tatcggctat tatgagggca gaagcccatc tactctatcg gatgatggaa
    18841 tcccctcttg ttttgaacga ttaccgtttg cgagaagact ttgcatttgc tacacctgaa
    18901 tttcaggtct tatatgactt gcttggccag tatggaaatc ttcctccaga agttttagca
    18961 gagcagacag aggaagttga aagagcttgg taccaagttt tagctcagga tttgcctgct
    19021 gagatatcgc cgcaggaact tagtgaagta gagatgactc gaaacaaggc tctcttgaat
    19081 caggacaata tgagaatcaa aaagaaggtg caggaagcta gccatgtagg agatacagat
    19141 acagccctag aagaattgga acgtttaatt tcccaaaaga gaagaatgga gtaataatgg
    19201 caacaaaaca aaaagaagta acaacatttg acgtacaggt agcagaattt atccgtaatc
    19261 ataagcaaaa agggacagca acagatgatg aaatcaatgc aagtctggtt attcctttta
    19321 ccttggacgc tgatgggatt gaagatctct tgcaacggat tcaggatgca ggcatttcta
    19381 tcacagataa cgaaggaaat ccaagtgcgc gtgttctcag caatgaagaa gaaccagaac
    19441 tcagcgatga ggacttgatt gggtcaactt ctgctaaggt caatgaccct gtccgtatgt
    19501 acttgaaaga aataggggtc gttcctctct tgaccaatga agaggagaaa gagttggcac
    19561 tggctgttga agctggtgat atcgaagcca aacaacgtct tgcggaagcc aatcttcgtt
    19621 tggttgtttc cattgccaaa cgctatgtcg gtcgtggtat gcagttcctt gacttgattc
    19681 aagaaggaaa tatgggcttg atgaaggcgg ttgacaagtt tgactattct aaagggttca
    19741 agttttcaac ttatgcaact tggtggattc gtcaggctat cactcgtgct attgcggacc
    19801 aagctcgtac catccgtatc ccagttcaca tggttgaaac tatcaataaa ttggttcgtg
    19861 aacagcggaa tctccttcaa gaattggggc aagatccgac accagaacag attgctgaac
    19921 gaatggatat gacacctgat aaggttcgtg aaatcttgaa gattgcccaa gaaccagtat
    19981 ctcttgaaac tcctatcggt gaagaggacg atagccacct tggagacttt atcgaagatg
    20041 aagtgattga aaatccagtg gattatacga ctcgtatcgt cttgcgtgag caattggatg
    20101 aaatcttaga tactcttaca gaccgtgaag aaaatgttct gcgtctacgt tttggactag
    20161 atgatggaaa aatgcgcaca cttgaagatg tggggaaagt ctttaacgta actcgtgagc
    20221 gtatccgtca gattgaagca aaggctttga gaaaactacg ccaaccaagt cgtagcaaac
    20281 cgcttcgtga ttttattgaa gactaagagt gaggaaaata tggcttatac agaagagcaa
    20341 attgaaaaca tcaaaacacg gattttaaca gccttggaag aagtcatcga ccctgagttg
    20401 ggaatcgata ttgtcaatct tggtttgatc tatgagattc gttttgacgg tgacacaggg
    20461 caaacagaga ttgacatgac tttgacaact atgggttgtc ccttagcaga ccttttgaca
    20521 gaccagattt atgatgctat gatagaggtt ccagaagtaa cggatactga ggttaaatta
    20581 gtctggtatc cagcctggac agttgaaaaa atgagtcgct atgcccgcat tgccctaggc
    20641 attaagtaaa catataaaag catgtgagag actgttggaa aagcgaggaa atttcccctc
    20701 ttttcctcta gtctctcctt tcttttgctg attttattca aagaaaatga tataatagta
    20761 gttatggaga aaaagaaatt acgcatcaat atgttgagtt caagtgagaa agtagcagga
    20821 cagggagttt caggtgctta ccgtgaatta gttcgtcttc ttcaccgtgc tgccaaggac
    20881 caattgattg ttacagaaaa tcttccaatc gaggcagatg tgactcactt tcatacgatt
    20941 gattttccct attatttatc aaccttccaa aagaaacgct cagggagaaa gattggctat
    21001 gtgcatttct tgccagctac acttgaggga agtttgaaaa ttccattttt cttaaaggga
    21061 attgtgaaac gctatgtatt ttctttttac aaccggatgg agcacttggt tgtggtcaat
    21121 cctatgttta ttgaggattt ggtagcagct ggtattccac gtgaaaaagt gacctatatt
    21181 cctaactttg tcaacaagga aaaatggcat cctctaccac aagaagaggt agtcagactg
    21241 cgcacagatc ttggtcttag tgacaatcag tttatcgtag taggtgctgg gcaagttcag
    21301 aaacgtaaag ggattgatga ctttatccgt ctggctgagg aattgcctca gattaccttt
    21361 atctgggctg gtggcttctc ttttggtggt atgacagatg gttatgaaca ctataagaaa
    21421 attatggaaa atccccctaa aaatttgatt tttccaggca ttgtatcgcc agagcggatg
    21481 cgcgaattgt atgctctagc ggatcttttc ttgttgccta gttacaatga gctctttcct
    21541 atgactattt tagaagctgc gagttgtgag gctcctatta tgttgcgtga tttagatctc
    21601 tataaggtga ttttggaggg aaattatcgg gcgacagcgg gtagagaaga gatgaaagag
    21661 gctattttgg aatatcaagc aaatcctgct gtcttaaaag atctcaaaga aaaggctaag
    21721 aatatttcca gagagtattc tgaagagcat ctgttacaaa tctggttgga cttttatgag
    21781 aaacaagccg ctttagggag aaagtaaaaa gtgaggtaat ctatgcgaat tggtttattt
    21841 acagatacct attttcctca ggtttctggt gttgcgacca gtattcgaac cttgaaaaca
    21901 gaacttgaaa agcagggaca tgctgttttt atctttacga cgacagataa ggatgtcaat
    21961 cgctacgaag attggcaaat tatccgcatt ccaagtgttc ctttctttgc ttttaaggat
    22021 cgtcgctttg cctaccgagg ttttagcaag gcacttgaaa ttgctaaaca gtatcagcta
    22081 gatattatcc atactcagac agaattttct cttggcctgt tggggatttg gattgcgcgt
    22141 gaattgaaaa ttccagtcat ccatacctat cacacccagt atgaagacta tgtccattat
    22201 attgctaagg ggatgttgat ccggccgagt atggtcaagt atctggttag aggtttcctg
    22261 catgatgtgg atggggttat ttgccctagt gagattgtcc gtgacttgct atctgattat
    22321 aaggtcaagg ttgaaaaacg ggtcattcct actgggattg aattagccaa gtttgagcgt
    22381 ccggaaatca agcaggaaaa tttgaaagaa ctgcgtagta aactagggat tcaagatggt
    22441 gaaaagacgt tgcttagtct ttcgagaatc tcctatgaaa aaaatattca agcagtttta
    22501 gcagcctttg ctgatgttct gaaagaggaa gacaaggtta aactggtagt agctggggat
    22561 ggcccttatc tgaatgacct caaagagcaa gcccagaacc tagagattca agactcagtc
    22621 atctttacag ggatgattgc tcctagtgag acggctcttt actataaagc ggcggatttc
    22681 ttcatttcgg catcgacaag cgaaacgcaa ggtttgacct acttggaaag cttagccagt
    22741 ggaacacctg tcattgctca cggaaatcct tatttgaaca acctcatcag tgataaaatg
    22801 tttggaacct tgtactatgg agaacatgat ttggctggtg ctattttgga agccctgatt
    22861 gcaacaccag acatgaacga gcatacctta tcagagaaat tgtatgagat ttcagctgag
    22921 aactttggga aacgagtgca tgagttttat ctggatgcca ttatttcaaa taacttccag
    22981 aaagatttgg ctaaagatga tacggtcagt cagcgtatct ttaagacagt tttgtatctt
    23041 cagcaacagg tggttgctgt acctgtaaaa ggatctagac gcatgttgaa ggcttcaaaa
    23101 acacagttga tcagtatgag agactattgg aaagaccatg aagaatagaa agaggaacag
    23161 ctatgaaaaa aacaattaat gagaagcggt cgtgataaaa agattgcggg tgtttgtgct
    23221 ggggtggccc attatctgga tatggatccg actatcgttc aagtcatttg gggtgttctt
    23281 acttgctgtt acggagctgg aattgtagct tacattattt tatggattat cgcaccagta
    23341 gcaactgact attgaaaact agctcaattc atgctaagat aatagaaaat agaatgtaac
    23401 gaaggagaga aaaatggcat ttggagataa tggaaatcgt aaaaaaacta tgtttgagaa
    23461 aataaccttg tttatcgtga ttatcatgct agtagcaagt ttattgggaa tttttgcaac
    23521 tgcaattggt gccctcagta atctataaaa tagattcaag aaaatttagt gactgggatt
    23581 tcccagccct tttttaaagt gagaagaaat aatgagtatg tttttagata cagctaagat
    23641 taaggtcaag gctggtaatg gtggcgatgg tatggttgcc tttcgtcgtg aaaaatatgt
    23701 ccctaatgga ggcccttggg gtggtgatgg tggtcgtgga ggcaatgtgg tcttcgttgt
    23761 agacgaagga ctacgtacct tgatggattt ccgctacaat cgtcatttca aggctgattc
    23821 tggtgaaaaa gggatgacca aagggatgca tggtcgtggt gctgaggacc ttagagttcg
    23881 agtaccacaa ggtacgactg ttcgtgatgc ggagactggc aaggttttaa cagatttgat
    23941 tgaacatggg caagaattta tcgttgccca cggtggtcgt ggtggacgtg gaaatattcg
    24001 tttcgcgaca ccaaaaaatc ctgcaccgga aatctctgaa aatggagaac caggtcagga
    24061 acgtgagtta caattggaac taaaaatctt ggcagatgtc ggtttagtag gattcccatc
    24121 tgtagggaag tcaacacttt taagtgttat tacctcagct aagcctaaaa ttggtgccta
    24181 ccactttacc actattgtac caaatttagg tatggttcgc acccaatcag gtgaatcctt
    24241 tgcagtagcc gacttgccag gtttgattga aggggctagt caaggtgttg gtttgggaac
    24301 tcagttcctc cgtcacatcg agcgtacacg tgttatcctt cacatcattg atatgtcagc
    24361 tagcgagggc cgtgatccat atgaggacta cctagctatc aataaagagc tggagtctta
    24421 caatcttcgc ctcatggagc gtccacagat tattgtagct aataagatgg acatgcctga
    24481 gagtcaggaa aatcttgaag actttaagaa aaaattggct gaaaattatg atgaatttga
    24541 agagttacca gctatcttcc caatttctgg attgaccaag caaggtctgg caacactttt
    24601 agatgctaca gctgaattgt tagacaagac accagaattt ttgctctacg acgagtccga
    24661 tatggaagaa gaagcttact atggatttga cgaagaagaa aaagcctttg aaattagtcg
    24721 tgatgacgat gcgacatggg tactttctgg tgaaaaactc atgaaactct ttaatatgac
    24781 caactttgat cgtgatgaat ctgtcatgaa atttgcccgt cagcttcgtg gtatgggggt
    24841 tgatgaagcc cttcgtgcgc gtggagctaa agatggggat ttggtccgca ttggtaaatt
    24901 tgagtttgaa tttgtagact aggagactgg tatgggagat aaaccgatat ctttccgaga
    24961 tgcggatggt aattttgttt ccgccgcaga cgtttggaat gaaaagaaat tggaagaact
    25021 atttaatcgt ctcaatccaa atcgtgcctt gagattggca cgaactaaaa aggaaaatcc
    25081 atctcagtaa agaagctaaa aaatcccgtg cctcatcaga cacgggattt tgtggtacga
    25141 caggcatgta tagcaaactg aatctggaat agcacagcat atcttctaaa atatagtaaa
    25201 atgaaatgag aacaggacaa atcgatcagg acagtaaaat cgatttctaa caatgtttta
    25261 gaagcagaga tgtactattc tagtttcaat caactatatt gttataaatt gatttgaatt
    25321 tcaaaattaa attgtttgat tcttatttca atttgttata gtatatctga tgtcaaagtt
    25381 ctcggcgagt caaatagcga ttcccaagcc tgactatcgt gaggtagcgg attaaaatgg
    25441 tctggggata gaccgtttta agtctgacgc tggaaataag aattgtcaga agaagggata
    25501 gcgaaatcgt ggctctacga acaggaacgt gataataagg cgtatatagc ggataagagg
    25561 gcctcaaact ctaaagtcca aaaaggtagt cgtaacctat atgcgtaaat cacgagagta
    25621 attgaattcg tactaagatt ttctattttc actgtaacct tttaacgtcc tcgtatcttg
    25681 tatacacgag gaaagatgta cgacttatcc cgtgaggtct atcactataa agagaaaacg
    25741 acagatagaa gtgatcctga gtcacggtta tctttaaaat agattgtctg ataggacggt
    25801 atgtataaaa cgcttctgtg aactgagaga agggggagaa gttcttgcta aaatttagtt
    25861 gaacagccgt attccgatat ttagataagg gatctagtct tagctcctac tcagttttag
    25921 gggataaaaa aggggcaata gcgattcgag aaagattata ctcttcgaaa atctcttcaa
    25981 atcacgtcaa tatcgccttg ccgtatgtgt aggatactga ctacgtcagt tctatctaca
    26041 acctcaaaac agtgttttga gcaacctgcg gctagtttcc tagtttgatc tttgattttc
    26101 atttaaaatt gaaaaggatg gaaaaaagga taaatttatg atatacttta ttttgaagac
    26161 cttattagaa atcttgaaag agtattgaaa acttagaatg agaaaaattg ttatcaatgg
    26221 tggattacca ctgcaaggtg aaatcactat tagtggtgct aaaaatagtg tcgttgcctt
    26281 aattccagct attatcttgg ctgatgatgt ggtgactttg gattgcgttc cagacatttc
    26341 ggatgtagcc agtcttgtcg aaatcatgga attgatggga gctactgtta agcgttatga
    26401 cgatgtattg gagattgacc caagaggtgt tcaaaatatt ccaatgcctt atggtaaaat
    26461 taacagtctt cgtgcatctt actattttta tgggagcctc ttaggccgtt ttggtgaagc
    26521 gacagttggt ctaccgggag gatgtgatct tggtcctcgt ccgattgact tacaccttaa
    26581 ggcgtttgaa gctatgggtg cgactgctag ctacgaggga gataacatga agttatctgc
    26641 taaagataca ggacttcatg gtgcaagtat ttacatggat acggttagtg tgggagcaac
    26701 gattaatacg atgattgctg cggttaaagc aaatggtcgt actattattg aaaatgcagc
    26761 ccgtgaacct gagattattg atgtagctac tctcttgaat aatatgggtg cccatatccg
    26821 tggggcagga actaatatca tcattattga tggtgttgaa agattacatg ggacacgtca
    26881 tcaggtgatt ccagaccgca ttgaagctgg aacatatata tctttagctg ctgcagttgg
    26941 taaaggaatt cgtataaata atgttcttta cgaacacctg gaagggttta ttgctaagtt
    27001 ggaagaaatg ggagtgagaa tgactgtatc tgaagacagc atttttgtcg aggaacagtc
    27061 taatttgaaa gcaatcaata ttaagacagc tccttaccca ggctttgcaa ctgatttgca
    27121 acaaccgctt acccctcttt tactaagagc gaatggtcgt ggtacaattg tcgatacgat
    27181 ttacgaaaaa cgtgtaaatc atgtttttga actagcaaag atggatgcgg atatttcgac
    27241 aacaaatggt catattttgt acacgggtgg acgtgattta cgtggggcca gtgttaaagc
    27301 gaccgactta agagctgggg ctgcactagt cattgctggg cttatggctg aaggtaaaac
    27361 tgaaattacc aatatcgagt ttatcttacg tggttattct gatattatcg aaaaattacg
    27421 taatttagga gcggatatta gacttgttga ggattaaacc gtagaggtgt ttatgaatat
    27481 ttggaccaaa ttagcaatgt tttctttttt tgaaacggat cgcttgtatt tgcgtccttt
    27541 cttttttagt gatagtcagg acttccgcga gatagcttca aatccagaaa atcttcaatt
    27601 tattttccca acgcaggcaa gtctggaaga aagtcaatat gcactggcca attactttat
    27661 gaagtcccct ttgggagtgt gggcaatttg tgaccagaaa aatcaacaaa tgattggttc
    27721 tattaaattt gagaagttag atgaaatcaa aaaagaagct gagcttggct attttttgag
    27781 aaaagatgct tggtcgcaag gatttatgac agaggttgtt agaaaaattt gtcagctttc
    27841 ttttgaggaa tttggcttaa aacaattatc tatcattacc caccttgaaa atgaagctag
    27901 ccaaagagtt gctcttaagt ctggatttag tttgttccgt cagtttaagg gaagtgatcg
    27961 ttacacaaga aaaatgcggg attatcttga atttcggtat gtaaaaggag agttcaatga
    28021 gtaagcatca ggaaattcta agctatttgg aggaattacc agtaggtaaa agggtcagtg
    28081 ttcgtagcat ttcgaatcat ctaggagtta gtgatggaac agcctatcgg gctattaaag
    28141 aagctgaaaa ccgtggaatt gtggagaccc gtcctagaag tggaacaatt cgtgttaaat
    28201 cccagaaagt tgctatagag agattaacgt ttgctgaaat tgcagaagtg acttcttctg
    28261 aggttctggc tgggcaagaa ggtttagaga gagaatttag caagttttca attggtgcca
    28321 tgactgaaca aaatatcttg tcttaccttc atgatggggg gctcttgatt gtcggagacc
    28381 gaacccgtat tcagttgcta gccttggaaa atgaaaatgc agttctggtt acagggggat
    28441 ttcaggttca tgatgatgtg cttaaactgg ccaatcaaaa agggattcct gttctaagaa
    28501 gtaagcatga tacctttacc gtcgcgacca cgatcaataa agccttgtca aatgtccaaa
    28561 tcaagactga tattctgaca gttgagaaac tttatcgccc tagtcatgag tatggttttc
    28621 tgagagagac agatacagtt aaagattatt tggacttggt tcgtaagaat cgtagcagcc
    28681 gtttccctgt tatcaatcaa catcaggtcg ttgttggcgt tgtaaccatg agagacgctg
    28741 gtgataaatc accaagcacg acaattgata aggttatgtc tcgtagtcta tttttggttg
    28801 gattatcgac aaatattgcc aatgtgagtc aacggatgat cgcagaagac tttgaaatgg
    28861 taccagttgt tcgaagcaat caaactttgc ttggcgttgt gacgcgacga gatgtcatgg
    28921 agaagatgag ccgttctcaa gtttcggctc taccaacttt ttctgagcag attggacaaa
    28981 agctctctta tcaccatgat gaagtagtca ttacagtgga accctttatg ctagaaaaaa
    29041 atggagtttt ggctaatggt gtattggcag aaattctgac ccacatgacc caagatttag
    29101 ttgttaatag tggtcgcaat ctcattatcg agcagatgct gatctacttt ttgcaggctg
    29161 ttcagataga tgatatattg cgcattcagg cacggattat tcatcatacg agacggtcag
    29221 ctataattga ttacgatatt tatcatggtc accagattgt ttcaaaagca aatgtgactg
    29281 ttaaaattaa ttagaaacta ggagaaaaga tgataacatt aaaatcagct cgtgaaatcg
    29341 aagctatgga caaggctggt gattttctag caagtattca tataggctta cgtgatttga
    29401 ttaagtcagg cgtagatatg tgggaagttg aagaatatgt ccgccgtcgt tgtaaagaag
    29461 aaaatttcct tccacttcag attggggttg acggtgccat gatggactat ccttatgcta
    29521 cctgttgctc tcttaacgat gaagtggctc acgctttccc tcgtcattat atcttgaaag
    29581 atggtgattt gctcaaagtt gatatggttt tgggaggtcc cattgctaaa tctgacctga
    29641 atgtctcaaa attaaacttc aacaatgttg aacaaatgaa aaaatacact cagagctatt
    29701 ctggtggttt agcagactca tgttgggctt atgctgttgg tacaccgtcc gaagaagtca
    29761 aaaacttgat ggatgtaacc aaagaagcta tgtacaaggg tattgagcaa gctgttattg
    29821 gaaatcgtat cggtgatatc ggtgcggcta ttcaagaata cgctgaaagt cgtggttacg
    29881 gtgtagtgcg tgatttggtt ggtcatggtg ttggcccaac tatgcacgaa gaaccaatgg
    29941 ttcctaacta tggtattgca ggtcgtggac tccgtcttcg tgaaggaatg gtcttaacca
    30001 ttgaaccaat gatcaataca ggcgattggg aaattgatac agatatgaaa actggttggg
    30061 cgcataagac cattgacggt ggattgtcat gtcagtatga acaccaattt gtcattacga
    30121 aagatggacc tgttatcttg actagccaag gtgaagaagg aacttattaa taaaaagtga
    30181 aaagactact ggaagtttat tatgaaaaaa tccagtagat cttttcataa taaaacgcat
    30241 tgtatcaagt gttaggggct gatatcatgc gtttttctgc ttttaagatt ttttccaact
    30301 ctgtttgtaa gcgcatcata acaaagggtc taggattcag ggctctcctc ctatatacta
    30361 ttagtaaagt aaaactaagg gaggatattt tagtgtcgca gtctattgtt cctgtagaga
    30421 ttccacaata ttgtcgtttt gattctaaaa agagaaatgg aattctgttt aatgttcgta
    30481 ttgccaatct taaatttacc ttttttagat tagactccct gcgaaacaaa acatggtata
    30541 gtagttctat gaatgatgaa gcaagtaaac aactaactga tgcacgattt aagcgttttg
    30601 ttggtgttca gcgcacgact tttgaagaga t
//
LOCUS       DBERXF010000026        30249 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.26, whole genome shotgun sequence.
ACCESSION   DBERXF010000026 DBERXF010000000
VERSION     DBERXF010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 30249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30249
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.26"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..197)
                     /locus_tag="ACL8JK_001297"
     CDS             complement(<1..197)
                     /locus_tag="ACL8JK_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGS1786173.1"
                     /translation="MEQLHFITKLLDIKDTNIQIIDVVNRDSHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLET"
     gene            380..1759
                     /gene="bglA"
                     /locus_tag="ACL8JK_001298"
     CDS             380..1759
                     /gene="bglA"
                     /locus_tag="ACL8JK_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGS1786174.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            1951..3759
                     /gene="glmS"
                     /locus_tag="ACL8JK_001299"
     CDS             1951..3759
                     /gene="glmS"
                     /locus_tag="ACL8JK_001299"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGS1786175.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEKYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKRALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(3836..3973)
                     /locus_tag="ACL8JK_001300"
     CDS             complement(3836..3973)
                     /locus_tag="ACL8JK_001300"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786176.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTDEISNHTYGKATLTWFEEI
                     F"
     gene            4030..5079
                     /locus_tag="ACL8JK_001301"
     CDS             4030..5079
                     /locus_tag="ACL8JK_001301"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HGS1786177.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLTAGAVNTKKIRLTSAVSILSSMDPIRLFQQYVTIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(5179..8976)
                     /gene="spuA"
                     /locus_tag="ACL8JK_001302"
     CDS             complement(5179..8976)
                     /gene="spuA"
                     /locus_tag="ACL8JK_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HGS1786178.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKSEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            9392..9805
                     /gene="rpsL"
                     /locus_tag="ACL8JK_001303"
     CDS             9392..9805
                     /gene="rpsL"
                     /locus_tag="ACL8JK_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGS1786179.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            9825..10295
                     /gene="rpsG"
                     /locus_tag="ACL8JK_001304"
     CDS             9825..10295
                     /gene="rpsG"
                     /locus_tag="ACL8JK_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGS1786180.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            10720..12801
                     /gene="fusA"
                     /locus_tag="ACL8JK_001305"
     CDS             10720..12801
                     /gene="fusA"
                     /locus_tag="ACL8JK_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGS1786181.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            12905..17296
                     /locus_tag="ACL8JK_001306"
     CDS             12905..17296
                     /locus_tag="ACL8JK_001306"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGS1786182.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMTPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVSRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            17398..17661
                     /locus_tag="ACL8JK_001307"
     CDS             17398..17661
                     /locus_tag="ACL8JK_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGS1786183.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            17654..17932
                     /locus_tag="ACL8JK_001308"
     CDS             17654..17932
                     /locus_tag="ACL8JK_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HGS1786184.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            17953..18105
                     /locus_tag="ACL8JK_001309"
     CDS             17953..18105
                     /locus_tag="ACL8JK_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786185.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            18127..19368
                     /locus_tag="ACL8JK_001310"
     CDS             18127..19368
                     /locus_tag="ACL8JK_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGS1786186.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVGGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            19378..19608
                     /locus_tag="ACL8JK_001311"
     CDS             19378..19608
                     /locus_tag="ACL8JK_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGS1786187.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            19831..20553
                     /locus_tag="ACL8JK_001312"
     CDS             19831..20553
                     /locus_tag="ACL8JK_001312"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGS1786188.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            20634..20822
                     /locus_tag="ACL8JK_001313"
     CDS             20634..20822
                     /locus_tag="ACL8JK_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786189.1"
                     /translation="MTWFEEIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFT
                     IDYTDDELLDKEAVFTTH"
     gene            20959..21138
                     /locus_tag="ACL8JK_001314"
                     /pseudo
     CDS             20959..21138
                     /locus_tag="ACL8JK_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            21175..21627
                     /locus_tag="ACL8JK_001315"
     CDS             21175..21627
                     /locus_tag="ACL8JK_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGS1786190.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            21918..22388
                     /locus_tag="ACL8JK_001316"
     CDS             21918..22388
                     /locus_tag="ACL8JK_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGS1786191.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            22407..23495
                     /locus_tag="ACL8JK_001317"
     CDS             22407..23495
                     /locus_tag="ACL8JK_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HGS1786192.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLVPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            23476..23904
                     /locus_tag="ACL8JK_001318"
     CDS             23476..23904
                     /locus_tag="ACL8JK_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS1786193.1"
                     /translation="MELEISDFLGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKIYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            24040..24990
                     /gene="prmA"
                     /locus_tag="ACL8JK_001319"
     CDS             24040..24990
                     /gene="prmA"
                     /locus_tag="ACL8JK_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGS1786194.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPFWTDYEATAGEMIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNTG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            24992..25735
                     /locus_tag="ACL8JK_001320"
     CDS             24992..25735
                     /locus_tag="ACL8JK_001320"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGS1786195.1"
                     /translation="MQQYFVKGSAVSPVTIEDRETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            25746..27542
                     /gene="pepF"
                     /locus_tag="ACL8JK_001321"
     CDS             25746..27542
                     /gene="pepF"
                     /locus_tag="ACL8JK_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGS1786196.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRAMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            27788..28579
                     /locus_tag="ACL8JK_001322"
     CDS             27788..28579
                     /locus_tag="ACL8JK_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HGS1786197.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALIYANLLSADANQ
                     QSVFYQELNAGFRNVLLNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFYKFSNFRSCLVEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            28690..29358
                     /locus_tag="ACL8JK_001323"
     CDS             28690..29358
                     /locus_tag="ACL8JK_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGS1786198.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPTVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVDGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(29383..29556)
                     /locus_tag="ACL8JK_001324"
     CDS             complement(29383..29556)
                     /locus_tag="ACL8JK_001324"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786199.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVADRTDEVSNHTYGKVKLTWFEEI
                     FEEYHTKKPCSSR"
     gene            complement(29568..30101)
                     /gene="queF"
                     /locus_tag="ACL8JK_001325"
     CDS             complement(29568..30101)
                     /gene="queF"
                     /locus_tag="ACL8JK_001325"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HGS1786200.1"
                     /translation="MKHQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT         8541 a         5702 c         7184 g         8822 t
ORIGIN      
        1 gtttcaagat aaggaatttt agaaggtttt tgaaagtcat atttcttcaa ttggtttccg
       61 cactcagggc aagatggggc gtcgtagtcc agtttggcga tgatttcctt gtgtgaatcc
      121 ctattgacga catctataat ttggatattt gtgtctttga tatcgagtag ttttgtgata
      181 aaatgtaatt gttccatatg aatctttcta atgagttgtt tggtcgcttt tcattataga
      241 tcttatggga ctttttttct acaataaaat aggctccata atatctatag tggatttacc
      301 cactacaaat attatagagc cgtttttacc ttgttttttc tgtataatgg gagaaatgag
      361 tagataaaga ggtaaatgta tgctaagatt tccaaaggat tttgtctggg gatcctctac
      421 ttctggaccg caaacagaag gacgtgtagc tggtgacggt aagggagaca atctctggga
      481 ttactggttc caagtggagc caaatcgtta ctataatggg attggttcag ataagacatc
      541 gactttttat gaaaattggg agcgggatat tgagcttttg ttagagactg gtcacacagc
      601 ctttcggact tctattcagt ggtcacggat ttttccacaa ggctgtggaa aagtcaaccc
      661 tcaaggtgtg gatttttatc gtaaggtctt tgaggctatt aaggctaaag gaattcgtct
      721 gttagtcaat ctctatcatt ttgatttacc ttttgccctt caagaggatg gtgatggttg
      781 ggaaaataag gcgacagtct cagcctatga agactatgct cgtttttgtt ttgagactta
      841 tggagattta gtggatcaat ggattacctt taacgagccc atcgttcctg tagaatttgg
      901 ttatttttat gatgcccatt atccacataa ggtggatgca gaggcagctg ttaaggtagc
      961 ctatcataca caattggcca gcagccgggc tgttaaggct tgccatgaac ttttgcctga
     1021 ttccaagatt gggattgtcc tcaacttgac accggcttat ccacgtagcc agcatcctgc
     1081 tgatgtcaag gcagctcgta ttgcggccct ttttcaggcc caatctttct tagatccatc
     1141 tgtcttggga acttatccac aggagttagt agaaatcttg catgaacacg gtcttttacc
     1201 tgatgctaca gaggaagagt tggaactcat tcgtgataat acggtggact tccttggtgt
     1261 gaactactat caacctttgc gtgttatggc tcctcgattt gctaagcatc cagagagtcc
     1321 actcttacca gaacattttt acgagcctta tgtgatgcct ggacgtaaaa tcaattctca
     1381 ccgtggttgg gagatttatg agcaagggat ttatgacatc gcccaaaata tcaaggaaaa
     1441 ttatggcaat attgagtgga tgttgactga gaatggtatg ggtgttgaag gggaagaaaa
     1501 attccgtcaa gatggaatga ttcaagatga ttaccgtatt gactttgtaa aaggtcatct
     1561 tcgtgaactt caccgtgcca ttgaagatgg tgccaactgt aagggctact tgatttggac
     1621 ctttattgac tgctggtcat ggctcaacag ctataaaaat cgctatggtt tggtcgaatt
     1681 agacttggaa acgcaagaac gtcgtctgaa gaaatcaggc cactggttca aagaattaag
     1741 cgataataat ggattttaaa aaggactctg actgattatc ccaatcggtc agagtttttt
     1801 gcttacagga gcttaatttg aactatacca atttttactc ttgacaagtg aaagaaacaa
     1861 gtatatactg tttttgctga ttctataaaa gatgaattag actataccaa ttttaaggag
     1921 aaagcacagc ttgcctgtgt cgtatatact atgtgtggaa ttgttggtgt tgttggaaac
     1981 acaaatgcaa ctgatatttt gattcaaggg cttgaaaagc ttgaataccg tggctatgat
     2041 tctgcgggaa tttttgtcct agatggtgct gataaccatt tggtgaaggc tgttggtcgt
     2101 atcgcagaat tgtctgccaa gacagctggt gttgagggaa caactggtat cggacatact
     2161 cgttgggcaa ctcatgggaa accaacggaa gacaatgctc acccacaccg atctgagaca
     2221 gaacgttttg tcttggttca caatggggta attgaaaact accttgaaat taaagaaaaa
     2281 taccttgctg ggcaccactt caaagggcaa acagatacgg aaatcgccgt acatttgatt
     2341 ggaaaatttg cggaagaaga cggtctctca gttcttgaag cctttaaaag agctcttcat
     2401 attatccgtg gttcatatgc ctttgccttg attgactctg aaaatccaga tgtcatctat
     2461 gtagcgaaaa acaaatctcc acttttgatt ggtcttgggg aaggctacaa tatggtctgc
     2521 tcagacgcca tggctatgat tcgtgaaact aaccaataca tggaaatcca tgaccaagag
     2581 ttggtaatcg tcaaggctga tagtgtggaa gttcaagact atgatggaaa tcgtcgtgag
     2641 cgtgctagct acactgctga acttgacttg tcagatatcg gtaagggaac ttacccttac
     2701 tacatgctca aggaaattga cgagcaacca actgttatgc ggaaactcat ccaagcctac
     2761 acagatgagg ctggtcaagt tgtcgtagac ccagatatca ttaaggctgt tcaagacgca
     2821 gaccgcatct acatccttgc agctggaaca tcttaccatg caggatttgc ttctaagaaa
     2881 atgttggaag aattgacaga tacaccagtt gaacttggaa tctcatctga gtggggctac
     2941 ggtatgccac ttctcagcaa gaaaccactc ttcatcttta tcagccaatc tggtgaaaca
     3001 gcggatagtc gtcaagtttt ggtcaaggct aatgaaatgg gaattccaag cttaacagtg
     3061 acaaacgttc caggttcaac cctctcacgt gaagccaact ataccatgct ccttcacgca
     3121 ggtcctgaaa ttgccgtggc atcaactaaa gcctatacag cgcaaatcgc agcccttgcc
     3181 ttccttgcaa aagcagtcgg agaagcaaat ggtaatgcta aagcgcaagc ctttgacctg
     3241 gttcatgaat tgtcaatcgt agctcagtct atcgaatcaa ctctttcaga gaaagaaacc
     3301 attgaagcca aggttcgtga acttcttgaa acaactcgta acgcctttta catcggacgt
     3361 ggtcaagatt actacgtagc catggaagca agtctcaaac tcaaagagat ttcttatatc
     3421 cagtgtgaag gttttgcggc aggagaactc aagcacggaa ccattgcctt gattgaagaa
     3481 ggaacgcctg ttttggctct cttgtcagat ccagttcttg ccaaccatac tcgtggaaat
     3541 atccaagagg tcgcagcccg tggtgccaaa gtcctcacta tcgcagaaga gaatgtagcc
     3601 aaagataccg acgatatcgt ccttacgacc gtacatccat acctctcacc aatttcaatg
     3661 gtcgtaccaa cgcaattagt cgcttacttt gcaaccctcc accgtggcct cgatgtggat
     3721 aaaccacgta accttgctaa atcagtaacg gtagaataag ctaaaaaagt ctagttatct
     3781 aggctttttc taatgagcaa attggttgct tgtacttaag attcgtgtta tactcttaga
     3841 aaatctcttc aaaccacgtc aacgtcgcct tgccgtaggt atggttactg atttcgtcag
     3901 ttctatccac aacctcaaaa cactgttttg agcaacctgc ggctagcttc ctagtttgct
     3961 ctttgatttt cattgagtat tagaataatt tttcaaattg aaggacagag atagacaagg
     4021 agaatcacaa tggtagaatt gggaatttca acatttgggg aaataacgga gcttgaaggg
     4081 actggacaaa cttacagtca tgctgaacgc attcgccagt tggtggcaga gattgagctg
     4141 gctgacaagg ttggtttgga cgtatatggg attggcgagc accatcgggc ggattttgca
     4201 gtatcagccc cagagattgt cctgaccgct ggggcagtca ataccaagaa aatccgtttg
     4261 accagtgcag tcagcattct gtcaagcatg gacccgattc gtttgttcca acagtatgtc
     4321 actatcgatg ctttgtcaaa tggacgagcg gagattatgg ctggaagggg ctctttcacg
     4381 gaatctttcc ctctgtttgg ttatgacttg aaagactacg actctctttt tgatgagaaa
     4441 ttagacttgc ttcagttagt caatgaaaag accaagttag actggcaagg tcgattgact
     4501 caaacgattg ctggtaaaga agtttatcct cgtccagttc aggacaaatt gcccttgtgg
     4561 atagctacag gtggtcatgt cgaatcaaca gtgaagattg ctcaggctgg tctaccgatt
     4621 gtatatgcta ttattggtgg taatccacgt tattttaaaa agttgattca ggcttatcgt
     4681 gagattggaa gcgaagcggg ccatgctgac aaagacttga aagtgggagc ccattcttgg
     4741 gggtggattg cggaagatgg tgagcaggcg gtgaaagatt atttccatcc gactaagcaa
     4801 gtggtggatg ctatttccaa agaccgtccg cactggcagg aattgcgtta tgagcaatat
     4861 ttggagcagg tagggccaaa tggcgccatg tttgttggca atccagatca ggtggccgaa
     4921 aaattgattc gcatgataga ggatttagga ttggaccgct tcatgcttca tctaccgctt
     4981 ggttctatgc ctcatgacca ggttctgaga gctattgaac tcttcggaac acaagttgca
     5041 cccaaagtac gagcttattt tgctatgaaa gaggcttaat aaaaaatcct aatcaagttt
     5101 attaggacaa caaatattgt acaaaaatta atcccccgag ctataatgct tgggggattt
     5161 ttctatagga gggctagttt agttctcttt tttatttttt agtaagaaac cgagaccaag
     5221 gagcgcaagg aggctgattc ctgcaaatag gagtttgttt tcgtttttga ttcctgtatt
     5281 tggaagttca gcttgtttat ctggggttgc aggtatattt tccttgctag agttttctac
     5341 cgattcgttt cgaaccgctt cttttacaga tgatgcttgt gcttcttgtg ctggttgttc
     5401 agcttgtgaa tcagctgtag cttggctagg tttattttcc gcatcagcta ctttggcatc
     5461 tggtttagta gaatcaggtc tagcttctgg agctgggtct tgatgtgcag ggtgagaagc
     5521 ttcattttga tgttcaggct tggaaggggt tgagtctggt ttctcttctg cagttgactc
     5581 atggctagtt ccattttgag agactcgaag aacagtagct gtaagggcat tcaatttcaa
     5641 gcctttttca gtccattcaa gtcctttcgg gttggcaatt ccgactgatc ctgcttggtt
     5701 ttcatctgcc aaaacttccg catttcttag atgtgcaaag gcagttccca aattaaattc
     5761 gcgagctttt tcatccgcat tgacaaagac tgcgtagata tcgccgtttg gagcagtgat
     5821 ttggtagcca atcactacat cctctttttc cacaccattt tggcctggga cagtgatgag
     5881 gtggacacgg tctttgatat cttggagact cttaagtcgg aaggcatctg tagattgacg
     5941 aagggcaatc aaacctttca tatagtcacg gctcttgaca ttttcaggat aagctttacc
     6001 atctgtagcc ttagtccagt caaacttgtt gactgcgtcg ctagaatcgt aagaatcatg
     6061 gatgaagtaa ggatagtcaa atgggttgcc gtccttatca cgcaacaagt gagatttgtt
     6121 tggaacctta tcctctgcta ctggagtctt gtaggctggg tcacggaatt gtttagtacg
     6181 tccatattcc tgaccggagt ggataaatgg agttccttga gctgtcaaga ccatgagatt
     6241 tccaagtcgt aaacgacggt ggatttcagc atagttctca gccttgcttg ggtctttttt
     6301 gatagactgg gcaatgatgt caaagagggt caagttatca tgggctgcga tgtattggat
     6361 gacatctcca gggctgtcag cttcaaagtt agttggttga gcaatgagat ttttaaagat
     6421 ggtgttgaca tcacgcttgc cacctgtgat aaaggcaggt tgaccttcgt ttggataacc
     6481 agatttgagg ttgttacgga tgtcatctga aaagacagcg acagtatcgg tatgtttcat
     6541 ccaatcttgg tcagcagctt tagtaggcat gttttcatca ccggcatagg ttctccaacc
     6601 ttcaccaagc atgatgaggt ttggattgag ggcgcgtgca gccttgtaag cttcttcgat
     6661 agaagcggcg tcatggtctc ccatcatatc gaagcggaag ccatccactt tgtaggtatc
     6721 aactaggtat ttgatagagt caactaggag ccgtttggtc atatggtggg ttgtccccaa
     6781 gcgtccacca ccaaagctag ttcgaggtgt gccatcggca tccataaagt ggtagtagtt
     6841 tggctctagg tcttcaaaga tatcgacttt ggctgtgtgg ttataaacga catctaggat
     6901 agctcccata ccacgtttgt ggatttcgtt gatgaggttt ttaaattctg cgattcgttt
     6961 ttctggattc ttaggatcgc ttgagtacat accagtcaag gagaagtagt tttgagggtc
     7021 atatccccag ttgtagttgc tgttgcttga agcgtagtca gacaagcgtt catggttttt
     7081 caattcattg acaaagtagt aagacaagac tggaaggagc tggatatggg ttacacccaa
     7141 gtctttgaga tagtctagtt tttcaatgaa ggcttcaaaa gtcccaaatg gtttggtcaa
     7201 gtcttttgca atggcaggat ctgaagtgaa gtcacgcaca tgagcttcgt agataacggc
     7261 gtcttcacga gtcttgaaat tgtgaatctt accataagtc aagtcttgag gtccgagttt
     7321 agctggatct acaaaggcgg ctttagccac tttatgggca tcgtcaattt tggcatcgtc
     7381 gctattccaa gcagcaagag atttagcgta aggatcgagt gcaagaacag ttttaccttg
     7441 acgctcgatt tggtattgat aatagtagcc agtgaaatct gtgattccga gtttgtttgt
     7501 gctgtctaga gtttgtttcc aagttcctct ttcccctttt tcgagagcga cagttccaac
     7561 tactttgtca gggtcattct tgtcgtagac aacaacagaa accttatcag cacttggtga
     7621 ccaaagggtc aaatcaactt gttttccttc ttcttttagg tcagctccca gtttgccatc
     7681 atagctgtat gtctcatctt tcaggcgcca gcttgttttg gtagtgaatt ggtcggaatt
     7741 gtagctaaca gtataaggat gttttgtgtc agagaaatct ccgctgtagg tcactttctt
     7801 accagcttca tcgattgcaa catcggtaat agttaccttg tttcctaggt gattagtgat
     7861 gttggagtgt ttgaggatat cttctttttt agcaccgaca agtgttgaaa agctactttc
     7921 aatgctagaa gtgcctacgt gttgggctcc tgtcatacgg atatcatgga catagtatgg
     7981 atttgtgtaa atcgattcat catcgtcttt taggaaaatt tggctatgat ttttcaaatc
     8041 tgtgaactta taattttctt tacggatttt cacgtcgtct ccttgtttgc tctcatctag
     8101 taataaaaat ccaaattctc ttgcggcttc attaagagga atgtcgatat agcggccata
     8161 tttgcctgta gccgtaaagt ctgttccgtc aggccattga gcgctacttg gattttttac
     8221 atctccccag taccagagag atttcttgtc atagttgcca tctgtgcggt agtagttgac
     8281 gcgaacagtt cctgcaggct gtggctcgta agagaaaacc ttgtaatctt ggtctaacca
     8341 agcctcgttc atttttggaa ctagtttttc tacagattta tcgccggtta gattttttcc
     8401 agctgtattg ttgatgagga agctaatttt cttggcttgt tctcccttta atttgacatc
     8461 taggtaatag ccgtagtcat ctttcttggc atccttgaag gacaaagctc cgtttggcca
     8521 gttttcagat ggtttttcaa catcgtccca agtccatagt ccttgagcat ccttgttttc
     8581 ttcaggaagt tttttgacat ggatacggaa gtagttatct tcgatgggct cttctgactt
     8641 agtttcagtt gttactggac tagtagaagt agttggctct gttgcaggtt tttcttctgt
     8701 tttctctagg gaagcgtttg catttctagg tgaagaaata tcactttcgt tcttaccaga
     8761 gccagctgct gtatcagtaa gaggttgggc aagggtggtt gtatttctgt tgttgggttc
     8821 gttagtggtt ggtgtacttt cgtcggatga gatagttggt gtagccatgg caagcaagac
     8881 aaggcttgcg ccgataagga cagaaccagt tccatttttg agggaacgga tgctgtagac
     8941 catttttttc tcagtgtgag atggtgtttt tctcataatg attctccaat caataaattt
     9001 ctatatcagt atagcatgta gtaaaacaat atgcaagcgt tttctttgat ttgtgaaaaa
     9061 attcttactt ttgagaagtt ttctgtacta ttttatatat cagtataaat gacggagata
     9121 aaaatgtcac ataagccaag ccgtattatt aggaagatga tgtgttccca gctattttta
     9181 ttcagaaatt gatctctaac attaccaata aaaaagaaaa atatcttgac aagcaaggga
     9241 aaattttgtt acaataatag acggtacttt ttacttttgg tctctcaaga gtgtacaggg
     9301 acgtgctgac aaatgttgca aaagtacaca cagatgatat ctgtcaccaa gtgtatcatc
     9361 accaaaaata aaaaaacaca ggagaatgta gatgcctaca attaaccaat tggttcgcaa
     9421 accgcgtaaa tcaaaagtag aaaaatctaa atcaccagct ttgaacgttg gttacaatag
     9481 tcataaaaaa gttcaaacaa acgtttcttc accacaaaaa cgtggtgttg caactcgtgt
     9541 tggaacaatg acacctaaaa aacctaactc agcccttcgt aaattcgctc gtgtacgttt
     9601 gagcaacctt atcgaagtta ctgcctacat cccaggtatc ggacacaact tgcaagagca
     9661 cagcgtggtg cttcttcgcg gtggacgtgt aaaagacctt ccaggggtac gttaccatat
     9721 cgtccgtggt gcacttgata ctgcaggtgt taacgatcgt aaacaaggtc gttctaaata
     9781 cggtactaaa cgtccaaaag cataaggaaa ggggataaag agaaatgagt cgtaaaaata
     9841 gagctccaaa acgtgacgta ttgccagatc cgctatacaa ttcacaacta gttactcgtc
     9901 ttatcaaccg cgttatgctt gatggtaaac gtggtactgc tgcttcaatc gtttacggtg
     9961 cttttgagca aatcaaagaa gctactggca acgatgcact tgaagtattt gaaacagcta
    10021 tggaaaacat catgcctgta cttgaagtac gtgcacgtcg tgttggtggt tctaactacc
    10081 aagtcccagt tgaagttcgt ccagaacgtc gtacaacact tggacttcgt tggttggtaa
    10141 caatcgctcg tcttcgtggt gaacacacaa tgcaagaccg tcttgcaaaa gaaatcttgg
    10201 atgctgctaa caacactggt gcagcagtta agaaacgtga agatactcac cgtatggctg
    10261 aagctaaccg tgcattcgca cacttccgtt ggtaagatag gatgcgaaag cgttaagaaa
    10321 gtcccagaga aaatagggaa tcgaagcagg ttgcggttgc aaccaatgag attcatcttt
    10381 ttctccagac ttttagcttg agctcaacta aatcatgatg ctaggaacgg taaggatgca
    10441 aggtgaaaat aggaaactga cgcagtattc gacgaataca aggagtttta tctttttcac
    10501 gcagcatccc gttccagctc acatcggcta actaacttta gcccgggttc aaattagcta
    10561 aatcgattag tattagctat aactcagctt accatctcgt aagttgaaac caacaatagc
    10621 atgaaaacat tgagaacggg taggtcctgc ctatccgttt ttattaaaat cgtgttataa
    10681 tagaatagaa atcaaaaata aataggagaa acaaacctca tggcacgcga attttcactt
    10741 gaaaaaactc gtaatatcgg tatcatggct cacgtcgatg ccggtaaaac aacaactact
    10801 gagcgtattc tttactacac tggtaaaatc cacaaaatcg gtgaaactca cgaaggtgcg
    10861 tcacaaatgg actggatgga gcaagagcaa gaacgtggta tcacgatcac atctgctgcg
    10921 acaacagctc aatggaacaa ccaccgcgta aacatcatcg acacaccagg acacgtggac
    10981 ttcacaatcg aagtacaacg ttctcttcgt gtattggatg gtgcggttac cgttcttgac
    11041 tcacaatcag gtgttgagcc tcaaactgaa acagtttggc gtcaagcaac tgagtacgga
    11101 gttccacgta tcgtatttgc caacaaaatg gacaaaatcg gtgctgactt cctttactct
    11161 gtaagcacac ttcacgatcg ccttcaagca aatgcacacc caatccaatt gccaatcggt
    11221 tctgaagatg acttccgtgg tatcattgac ttgatcaaga tgaaagctga aatctatact
    11281 aacgaccttg gtacggatat ccttgaagaa gacatcccag ctgaatacct tgaccaagct
    11341 caagaatacc gtgaaaaatt gattgaagca gttgctgaaa ctgacgaaga attgatgatg
    11401 aaatacctcg aaggtgaaga aatcactaac gaagaattga aagctggtat ccgtaaagcg
    11461 actatcaacg ttgaattctt cccagtattg tgtggttcag ccttcaaaaa caaaggtgtt
    11521 caattgatgc ttgatgcggt tatcgactac cttccaagtc cacttgacat cccagcaatc
    11581 aaaggtatta acccagatac agacgctgaa gaaactcgtc cagcatctga cgaagagcca
    11641 tttgcagctc ttgccttcaa gatcatgact gacccattcg taggtcgttt gacattcttc
    11701 cgtgtttact caggtgttct tcaatcaggt tcatacgtat tgaatacttc taaaggtaaa
    11761 cgtgaacgta tcggacgtat ccttcaaatg cacgctaaca gccgtcaaga aatcgacact
    11821 gtttactcag gtgatatcgc tgctgccgtt ggtttgaaag atactacaac tggtgactca
    11881 ttgacagatg aaaaagctaa aatcatcctt gagtcaatca acgttccaga accagttatc
    11941 caattgatgg ttgagccaaa atctaaagct gaccaagaca agatgggtat cgcccttcaa
    12001 aaattggctg aagaagatcc aacattccgc gttgaaacaa acgttgaaac tggtgaaaca
    12061 gttatctcag gtatgggtga acttcacctt gacgtccttg ttgatcgtat gcgtcgtgag
    12121 ttcaaagttg aagcgaacgt aggtgctcct caagtatctt accgtgaaac attccgcgct
    12181 tctactcaag cacgcggatt cttcaaacgt cagtctggtg gtaaaggtca attcggtgat
    12241 gtatggattg aatttactcc aaacgaagaa ggtaaaggat tcgaattcga aaacgcaatc
    12301 gtcggtggtg tggttcctcg tgaatttatc ccagcggttg aaaaaggttt ggtagaatct
    12361 atggctaacg gtgttcttgc aggttaccca atggttgacg ttaaagctaa gctttatgat
    12421 ggttcatatc acgatgtcga ctcatctgaa actgccttca agattgcggc ttcactttcc
    12481 cttaaagaag ctgctaaatc agcacaacca gctatccttg aaccaatgat gcttgtaaca
    12541 atcactgttc cagaagaaaa ccttggtgat gttatgggtc acgtaactgc tcgtcgtgga
    12601 cgtgtagatg gtatggaagc acacggtaac agccaaatcg ttcgtgctta cgttccactt
    12661 gctgaaatgt tcggttacgc aacagttctt cgttctgcat ctcaaggacg tggtacattc
    12721 atgatggtat ttgaccacta cgaagatgta cctaagtcag tacaagaaga aattattaag
    12781 aaaaataaag gtgaagacta atccgtcctc actctagaag gaagtcactt agtggcttcc
    12841 ttttgtcttt agaaaatacc tctaaatatg gtaaaatagt agaagaataa tgtgaggaaa
    12901 atgaatgtca aatagttttg aaattttgat gaatcaattg gggatgcctg ctgaaatgag
    12961 acaggctcct gctttagcac aggccaatat tgagcgagtt gtggttcata aaattagtaa
    13021 ggtatgggag tttcatttcg tattttctaa tattttaccg attgaaatct ttttagaatt
    13081 aaagaaaggt ttgagcgaag aattttctaa gacaggcaat aaagctgttt ttgaaattaa
    13141 ggctcggtct caagaatttt caaatcagct cttgcagtcc tactataggg aagctttctc
    13201 tgaaggtcca tgtgctagtc aaggttttaa gtccctttat caaaatttgc aagttcgtgc
    13261 tgagggtaat cagctattta ttgaaggatc tgaagcgatt gataaggaac attttaagaa
    13321 gaatcatctt cctaatttag ccaaacaact tgaaaagttt ggttttccaa cttttaactg
    13381 tcaagtcgag aagaatgatg tcctgaccca agagcaggaa gaggcctttc atgctgaaaa
    13441 tgagcagatt gttcaagctg ccaatgagga agcgctccgt gctatggaac aactggagca
    13501 gatgacacct cctccagcgg aagagaaacc agtctttgat tttcaagcga aaaaagctgc
    13561 agctaaaccc aagctggata aggcggagat tactcctatg atcgaagtga cgacagagga
    13621 aaatcgtctg gtatttgaag gggttgtttt tgatgtggag caaaaagtga ctagaacagg
    13681 tcgtgtttta atcaacttta aaatgacgga ctatacttca agtttttcta tgcaaaagtg
    13741 ggttaaaaac gaggaagagg cccagaagtt tgacctcatc aagaagaatt cttggctccg
    13801 agttcgaggg aatgtggaga tgaataactt cacacgcgat ttgactatga acgtacagga
    13861 tctgcaggaa gttgttcact atgagcggaa ggatttgatg ccagaaggtg agcgtcgggt
    13921 tgagtttcat gctcatacta acatgtcgac tatggatgct ttgccagagg tcgaagagat
    13981 tgttgcaaca gctgctaagt ggggacacaa ggcggttgct atcacagacc atgggaatgt
    14041 ccagtccttt ccacatggct ataaggcggc taagaaagcg ggaatccagc tgatctatgg
    14101 gatggaagcc aatatcgtgg aggaccgtgt ccctatcgtc tataacgaag tggagatgga
    14161 cttatcagaa gcaacctacg tggtctttga cgtggaaacg acgggacttt cagctatcta
    14221 taatgacttg attcaggttg cggcctctaa gatgtacaag gggaatgtta ttgctgaatt
    14281 tgatgaattt atcaatcctg ggcatccctt gtcagctttt actacagagt taactggaat
    14341 tacagatgat catgtcaaaa atgccaaacc actagaacaa gttttgcaag aattccaaga
    14401 attttgcaag gatacggtcc tagttgccca caatgctacc tttgacgttg gctttatgaa
    14461 tgctaattat gagcgtcatg atcttccaaa gattagtcag ccagttattg atacgctgga
    14521 gtttgctaga aacctctatc ctgagtataa acgccatggt ttggggcctt tgaccaagcg
    14581 ttttggtgtg gccttggaac atcaccacat ggccaactac gatgcggaag cgactggtcg
    14641 tctgcttttc atctttatca aagaggtagc agaaaaacat ggtgtgaccg atttagctag
    14701 actcaacatt gatctaatca gtccagattc ttacaaaaaa gctcggatca agcatgcgac
    14761 catctatgtc aagaatcagg taggtctaaa aaatatcttt aagctggttt ccttgtctaa
    14821 taccaagtat tttgaaggag tgtcacggat tccgagaacg gttctagatg cccatcgaga
    14881 gggcttgatt ttaggttcag cctgttcaga gggtgaagtt tttgacgtgg tcgtttctca
    14941 aggtgtggat gcggcggttg aggtggccaa gtattatgac tttatcgagg tcatgccacc
    15001 ggctatctat gcgcccttga ttgctaaaga gcaggtcaag gatatggagg aactccagac
    15061 cattatcaag agtttgatag aggttggaga ccgccttggc aagcctgttc tggctacggg
    15121 aaatgttcac tatatcgaac cggaagaaga gatttatcgt gaaattatcg tccgtagttt
    15181 gggacagggt gcgatgatta accgaactat cggtcatggt gaacatgccc aaccagcacc
    15241 acttccaaag gctcattttc gaacgactaa tgagatgttg gatgaatttg cctttttggg
    15301 agaggaactg gctcgtaaac tggttattga aaacaccaat gccttggcag aaatatttga
    15361 acccgttgaa gtcgttaagg gtgacttgta tacgcctttc atcgacaagg ctgaagaaac
    15421 agttgctgag ttgacctata agaaagcttt tgagatttat ggaaatccgc tgccagatat
    15481 tgttgatttg cggattgaaa aagaattaac atccatactg gggaatggat ttgctgtgat
    15541 ttatctggca tcgcagatgc tggtgcaacg ttctaatgaa cggggttatt tggttggttc
    15601 tcgtgggtct gtcggatcta gtttcgttgc gaccatgatt gggattacgg aggtcaatcc
    15661 tctctctcct cactatgtct gtggtcagtg tcagtacagt gagtttatca cagatggttc
    15721 gtacggctca ggatttgata tgccccataa ggactgtcca aactgtggtc acaaactcag
    15781 taaaaacgga caggatattc cgtttgagac cttccttggt tttgatgggg ataaggttcc
    15841 tgatattgac ttgaacttct cgggagaaga tcagcctagc gcccacttgg atgtgcgtga
    15901 tatctttggt gaagaatatg ccttccgtgc gggaacggtt ggtacggtag ctgccaagac
    15961 tgcctatgga tttgtcaagg gttacgagcg agattatggc aagttttatc gtgatgcaga
    16021 agtagaacgc ctcgctcaag gagcggcggg tgtcaagcgg acaacaggcc aacacccggg
    16081 gggaatcgtt gttattccga actatatgga tgtctacgat tttacgcctg tccagtatcc
    16141 agcagatgat gtcacggctg aatggcagac cactcacttt aacttccacg atatcgatga
    16201 gaacgtcctc aaactcgatg tactggggca tgatgatccg accatgattc gaaaacttca
    16261 ggatttgtct ggtattgacc ctaatgaaat tcctatggat gacgaaggcg tgatggcact
    16321 cttttctggg actgatgtgc taggggtaac acctgaacaa attggaacgc ctacgggtat
    16381 gttggggatt ccagagtttg gaacaaattt cgtacgtgga atggtagacg aaacccatcc
    16441 gacaaccttt gcggaattgc ttcagctgtc tggtctgtcc cacggtactg acgtttggtt
    16501 ggggaatgct caggatctga ttaagcaagg aatagcggac ctatcgactg ttatcggttg
    16561 tcgggacgac atcatggttt acctcatgca tgcgggtctg gaacctaaga tggcctttac
    16621 cattatggaa cgggtacgta agggtttgtg gctaaagatt tcagaagagg agagaaatga
    16681 ctatatcgaa gccatgaagg ctaataaggt gccagagtgg tatatcgaat cctgtgggaa
    16741 aattaagtac atgttcccta aggcccatgc ggcagcctac gttatgatgg ccttgcgtgt
    16801 agcttacttc aaggttcacc atcctattta ttactactgt gcttacttct ccattcgtgc
    16861 taaggctttt gatatcaaga ccatgggtgc gggcttggag gtcatcaagc gcagaatgga
    16921 agaaatctct gaaaaacgga agaacaatga agcctctaat gtggaaatcg atctctatac
    16981 aactcttgag attgtcaatg agatgtggga acgaggtttc aagtttggta aattagatct
    17041 ctactgtagt caggcgacag agttcctcat cgacggggat acccttatcc caccatttgt
    17101 agcaatggat ggtctgggag agaacgttgc caagcaactg gtgcgggcgc gtgaagaggg
    17161 agaattcctc tctaaaacag aactacgcaa gcgtggtgga ctctcatcaa ccttggttga
    17221 aaagatggat gagatgggta ttcttggaaa tatgccagag gataaccagt tgagtttgtt
    17281 tgatgagttg ttttaaaaaa ttgcttaata atctattaaa agaggctaac gtatatccaa
    17341 tagatttaca ttagctttct tttttgttaa aatagtctat ggaaagaggg tgagagtatg
    17401 tcaaagatga gtataagcat ccgtctggat agtgaggtta aggagcaggc ccaacaggtg
    17461 tttagtaatc tgggaatgga tatgacaaca gctattaata ttttccttcg tcaggcaatt
    17521 caatatcagg gattaccttt tgatgttaga ctagacgaaa atcggaagtt gctccaagtg
    17581 ttaacggatt tagaccaaaa tcgtaatatg agccagtctt ttgaatcagt ctcagatttg
    17641 atggaggact tacgtgctta agattcgtta tcataaacag tttaaaaaag attttaagtt
    17701 ggctatgaag cgtggtttga aggcagaatt attagaagaa gttttgaatt ttctggttca
    17761 agaaaaagaa catcctgcca gatatcgtga tcattcattg acggcatcca agcattttca
    17821 aggagttcgt gaatgccata cccagccaga ttggcttttg gtttataaag tagacaagtc
    17881 ggaattgatt ttaaatttgc tgaggacagg cagtcacagt gatttatttt aatctatttt
    17941 aagggggttc tcatgaaact aagaatattt gcggaagata agccggctaa gaaggtattt
    18001 gaatatcaat tagaacttgc tgatcgtaca attcttctat cgacagcact cttgtcaggt
    18061 gctattgctt tagcaggaat cttttctgct ttgagagaaa aataaaaata gaaaagagaa
    18121 aacagaatgg ttttaccaaa ttttaaagaa aatctagaaa aatatgcgaa attgttggtt
    18181 gcgaacggaa ttaacgtgca acctggtcac actttggctc tctctattga tgtggagcaa
    18241 cgtgaattgg cacatctaat cgtgaaagaa gcttatgcct tgggtgcgca tgaggtcatc
    18301 gttcagtgga cagatgatgt gattaaccgt gagaaattcc tccatgcccc gatggagcgt
    18361 ttggacaatg tgccagaata caagattgct gagatgaact atctcttgga gaataaggct
    18421 agccgtcttg gagttcgttc atctgatcca ggtgccttga acggagtgga cgctgacaag
    18481 ctttcagctt ctgctaaagc tatgggactt gccatgaagc ctatgcgtat cgcaactcaa
    18541 tctaacaagg ttagctggac tgtagcagct gcagcaggac ttgagtgggc taagaaagtc
    18601 ttcccaaatg ctgcgagcga cgaagaagca gttgatttcc tttgggacca aattttcaaa
    18661 acttgccgtg tctacgaagc agatcctgtt aaggcctggg aagagcatgc agctatcttg
    18721 aagagcaagg ccgatatgct taataaggag caattttcag cccttcacta cacagcgcca
    18781 ggaacagatt taacacttgg tttgccaaag aaccacgttt gggaatcagc tggtgctgtc
    18841 aatgcacagg gcgaaggatt cttgccaaat atgccgacag aagaggtctt cacagcgcct
    18901 gacttccgtc gtgcagatgg ttatgtcact tctacaaaac cgcttagcta caacggaaat
    18961 atcatcgaag gtattaaggt aacctttaag gatggacaaa tcgtagatat cactgctgag
    19021 aagggtgatc aggttatgaa agaccttgtc tttgaaaatg cgggtgcgcg tgccttgggt
    19081 gaatgtgcct tggtaccaga tccaagtcca atttctcagt caggcattac cttctttaac
    19141 acccttttcg atgaaaatgc gtcaaaccac ttggctatcg gtgcagccta tgcgactagc
    19201 gtcgttggtg gagcagagat gagtgaagaa gagcttgaag ctgcgggact taaccgttca
    19261 gatgttcacg tggattttat gattgggtct aatcagatgg atatcgatgg tatccgtgag
    19321 gatggaactc gagtacctct tttccgtaat gggaattggg caaattaagg agataatatg
    19381 ttaggaagta tgttcgttgg tctcctagtg ggatttttag caggtgctat gaccaatcgt
    19441 ggagagcgaa tgggatgttt tggaaaaatg tttctcggtt ggatcggagc ctttctaggt
    19501 cacttgctct ttggaacttg ggggccagtt ttatcaggaa cagctattat cccagctgtt
    19561 ttaggtgcca tgattgtctt agctattttt tggagacgag gaagttaatt tcctaaatct
    19621 gatactcaat gaaaatcaaa gagcaaacta ggaaactagc cgcaggttgc tcaaagcact
    19681 gctttgaggt tgcagataga actgacgaag tcagtaacat atatacggca aggcgacgtt
    19741 gacgcggttt gaagagattt ttgaagagta tgaaacgaaa aggaggttgg tcattgtact
    19801 agcctccttt tgatatgata taatagttct atgagattag ataaattttt agttgcctgt
    19861 gcggtgggaa gtcggactga ggtcaaaaac ttgctcaagg ctgggcgcgt gactgtaaat
    19921 ggtaaaaaag aaaaatcagc taaattgcag attgatgaaa aaatagatga gattcgcttt
    19981 gatgggcaag tgttggagta tgaagagttt gtctactaca tgatgaacaa gcccaaagga
    20041 gttatctcag cgactgagga tcccaagcac agaaccgttc tggacttgtt ggatgacttg
    20101 gcgcggagta aggaagtttt cccagtagga cgcttggata ttgacacgca tggtcttttg
    20161 ctcttgacca atgatggtca gctggctcat gttcttcttt cgcccaagcg tcatgtggac
    20221 aagacttatc tggcacaagt caagggaatc atgacccaag aagatgtgga gacatttgct
    20281 gagggtattc ctctcaaaga ctttacctgt caacccgcta tactggagct tgtatccata
    20341 gatacagaaa agaatcaaag ccaaatccgt gtgaccattg cagaagggaa gtttcatcag
    20401 atcaagcgta tggtgggcta ctgtggcaag gaagtggtgg acttgcaacg attgactatg
    20461 ggaactttag tattagatga gaacctggaa cgaggggaat ggcgtcgctt gaccaaggaa
    20521 gaattagaaa ttctccgcgc taatattatt taatttagtt taatactcaa tgaaaatcaa
    20581 agagcaaact aggaaactag ccgcaggctg tacttgagta cggcaaggcg acgttgacgt
    20641 ggtttgaaga gattttcgaa gagtatcagt ttgtaaaaat tggagataaa aaatatagag
    20701 tacgcagtgt tcctatgatt cattcaactc cgcctcaatc tgtcttagat cgagatactt
    20761 ttacaattga ctatacagat gatgaattgc tcgataaaga agcagttttt actactcatt
    20821 agaaaaatag gtatgaataa attggcttcc cttagaacca catctagggg cttttatgta
    20881 taatagaata ataagtatca ctcctttaca atacgtgtaa cacgtgttat aatggtgttg
    20941 tcaggaggta aaagcgctat gcctatgaca caaaaagaga tggttaaact ccttacggcc
    21001 catggttgga taaagactag aggcggtaaa ggctcccata ttaaaatgga aaagtaaggg
    21061 gaaagaccta tcacaatcct tcatggtaag ctgaataagt acactgaaag agggataaga
    21121 aagcaagctg ggttgtaaaa ttcagcccct gctttttgat atggaggtag tgaaatgtta
    21181 gttacgtatc cagctttatt ttattatgac gacacagacg gaacagaagc gacttatttt
    21241 gtccatttcc cagattttga atactcagct acacaaggag aggggatttc tgaggctttg
    21301 gctatggggt cggagtggct agggataact gttgcagatt tgatagagag tgatggagag
    21361 ttacctcagc catcagatat caatagcttg tctttaattg ataatgatcc ttttaaagat
    21421 gatgaagatt tcgtgtcaac ctatgacctt gataaatctt ttatttctat ggtatctgtt
    21481 gatgtatcag aatacctagg aagtcaggaa cccattaaaa agactttgac cataccaaaa
    21541 tgggcagata agttgggacg agaaatggga cttaactttt ctcagacttt gacagacgct
    21601 attgcagata agaaagttca agcctaagat taagcgtggt atcgtggtaa tagtcaataa
    21661 aaaagcacgt ccacttgtgc tagttactcg cctattgatt ttatagattt attagccctt
    21721 tcgagggctt tttatattga tttttatgag aaatgaagaa atcagacttt taagaaaatc
    21781 actgatacca agggtttaaa tgaggtaata tggtataatt aggacataaa ataattttgt
    21841 ggtaagatgg tagtatctat tttagcatat ttccgagcaa tcggggcgat taaagagtcg
    21901 catagaaaga ggacaaaatg gcaacatacg gatttttaga tattttagag gaagagttgg
    21961 acaagaactt tccctttgac tttgagatta gttgggacaa acgcaaccat gcggtagaag
    22021 tgagttttct attggaagcg caaaatgctg caggtgtgga gatggtggat gaagacggag
    22081 aggtttcatc agatgacatt ctttttgagg aagcggtcct tttctacaat cctgccaagt
    22141 caacagtcaa tgaggaagac tatttgactg ttattcctta cctgcctaaa aaaggatttt
    22201 cccgtgaatt tttagcttat tttgcgcttt tccttaaaga tactgctgag gttgggctag
    22261 atgtcctcat ggactttttg gaagacccag aagcagagga atttgtcatg gaatggaacc
    22321 aagaagtctt tgaagaagga aaagttggct tggaagaggg agaattttac ccttatccaa
    22381 gatactagga gttggttgga ggtgttatga agaaaattgg gacttatttg gtttatgtgc
    22441 tagctgttgt ctttattatg ctagcttttg cttgtggaac aatcgcattt gcagagttgg
    22501 ggtattccgc agttttagcc tttacttttg gttatgcctt cgctcttcta agcatgtatt
    22561 taatctttat tcttcatgag ctgggtcatg ctttttgtgg ctacttgaca ggctatcggc
    22621 tggtggcttt tggattagga cattttattt tgaccaaaaa gtcaggcagg tttcatctta
    22681 gtagaacagc cattctgaaa aatgttggtg ctcaatacat tggtttaaaa gaggatgaaa
    22741 gcgatcaaag aatcatcctg atgctttcag gaggcttgat ggttcatctc ggcttgatat
    22801 tattggcgat agtgtttgga tttttgacaa gaagctggta ttttgcaggg acttggattt
    22861 ttcttaattt atctttcttc ctaaataaca ttttgccagt cgacatcacc gatggagcaa
    22921 aaatttggga attactacaa caccctgaaa ataccaaata cgcctacctg gtattgagac
    22981 attctgctca aactttgctg gttcctcaag aatatgattt gaaagacttt gttcaagcag
    23041 ttcctgagga tgcacgaggg agttttgcgg atggtgtatt aggtatgcaa ggtgaagttt
    23101 ccattttgga agggaaggaa gaagtagcta aacagcagtt tcaagcatta cttgagagga
    23161 caactactcc gatgatgcag acagttgccc aactatccct gcttcatatc gccttgttgg
    23221 aaggagattt tgagcaagcg gagcaatatg ctagtattcg acaggtcaaa tcgtttctgt
    23281 ctctcaaact gtccaatctt caagtgatac aagcctggta tcaattaaag gtgaagaaag
    23341 atgtagatcg aactcgtaag gctctcaaga ttgctagaca gaaaatggat agtagtcgaa
    23401 tgttgaggga cgagaaacgc tattatgaaa acttgttagc agagctggaa aaggaaatgt
    23461 tagaaggaac tgaagatgga actagaaatt tctgatttcc taggctgtaa gattgctttg
    23521 ttttgtgggg ataagctttt gactatctta cgcgatgata aggcaagcat tccctgggcc
    23581 aatatgtggg aactgccagg tggtggacgt gaaggtgatg aaagtccttt tgagtgtgta
    23641 gcgcgtgaag tttatgaaga actgggcatt catctgactg aagattgtct gctttggagt
    23701 aagatttacc caagtatgct ttttgcagac aaacagtccg tttttctagt tggtcagttg
    23761 acacagaacc agtttgacag tatcgtattt ggagatgaag gacagggcta tcagctgatg
    23821 aatgttgagg aatttcttag ttccagtcaa gttgtgcctc agttgcaaga gagattaaaa
    23881 gattatttaa aagtaagtga ttagaaagga tggttcagtt acatttctaa actgaacccg
    23941 ccctaaacac tgtgccaaaa agataaactt ctcttagaca caagcgtctt cagagaattt
    24001 cctattttgg ttttgtgttt tacgggcttg gtattaataa tggaaacatg gcaagagtta
    24061 aaagttacag tgaagcgtga gggagaggag ttggtttcca atctcttgat tgagctggga
    24121 gcgcaaggag tcgcaatcga agacagtatg gactatgtgg gaaatgtgga ccgctttgga
    24181 gagattttcc cagaggtgga gcagcaagaa gaaatcgtag tgacagccta ctaccctgac
    24241 acggtggatg tgacagtggt tgaggcggat ttgcaggctc gtctagcaga attgacagat
    24301 tttatggatt tgggagagtt aaaaataggt acgactgcct tggctgagga agactgggca
    24361 gacaactgga agaaatacta tgagccagct cgtatcactc atgatttgac catcgttccc
    24421 ttttggacag actatgaggc gactgcgggg gaaatgatta tcaagctgga tcctggtatg
    24481 gcctttggga cagggaccca cccaacaacc aagatgagcc tctttgcctt ggaacaggtt
    24541 cttcgtggtg gcgaaacagt gctagatgta gggactggtt caggggttct ttctattgca
    24601 agctcactcc taggtgccaa ggagattttc gcctatgact tggatgatgt ggcggttcgt
    24661 gtcgctcagg aaaatattga gctcaacact ggtatggaaa atatccatgt agcagcagga
    24721 gacttgctta agggagttga gattgaagca gatgtcatcg tggctaatat cttggcggat
    24781 attctcattc atctgacgga ggatgcttat cgcttggtaa aggatgaagg ctacctcatc
    24841 atgagtggca ttatcaagga caagtgggac atggtgcgcc agtcggctga gtcagctgga
    24901 tttttccttg aaacccatat gattcaaggg gaatggaatg cctgcgtctt caagaagacc
    24961 aaggatattt caggtgtgat tggaggctag catgcaacag tattttgtca aggggagtgc
    25021 agtctctcct gtcaccatcg aggacaggga aaccagcaag catatgtttc aggttatgcg
    25081 cttgaaagaa gaggatgagg ttaccttagt ctttgatgat ggcatcaagc gcttggcgcg
    25141 cgtgctggat atggaaaatc gtcagtttga gttggtccaa gaattaaatg acaatgtgga
    25201 actaccagtc caagtgacca tcgcatctgg atttcccaag ggagacaagc tggagttcat
    25261 cgctcaaaaa gtaaccgaac tgggggctag ccaaatctgg gcctttcctg cagactggtc
    25321 agttgccaag tgggatggca agaaattggg taaaaaagtt gaaaaactag aaaaaattgc
    25381 ccttggagca gccgagcaaa gcaagcgtaa tattgtacca agtattaaac ttttcgagaa
    25441 aaaagcagat tttctagctc agctggacca gtttgactct atcatagtag cctatgaaga
    25501 atcagctaaa gaaggagaag ccgctgcgct tctgcaagca gtcactggtc ttgaaacagg
    25561 agccaaactg ctctttatct ttggtccaga aggcggtctc tcacctgcag aaatcgaaag
    25621 ttttgaagct aaaggagccg ttttggcagg cctaggtcct cgtattttgc gagcagaaac
    25681 agcaccgctt tacgctttat cagcccttag tgttttagta gaattagaga aataagagga
    25741 agaaaatgga acaaaaacac cgttcagaat ttccagagaa ggaactctgg gacttaacag
    25801 ccctatacca agaccgtgag gatttcttgc gtgcaatcga gaaagctcgc gaagacatca
    25861 accagtttag ccgtgattac aagggcaatc ttcacacttt tgaggatttc gagaaggcct
    25921 ttgcggaatt ggaacagatc tacattcaga tgagccatat tggcaactat ggttttatgc
    25981 ctcagacgac ggactatagc aatgacgaat ttgccaatat tgcccaagct gggatggaat
    26041 ttgaaacaga tgccagcgta gccttgacct tctttgacga tgccttggtg gcagcagatg
    26101 aggaagtctt ggaccgtttg ggtaaattgc cacatttaac agctgccatt cgtcaggcta
    26161 aaatcaaaaa agcccactac ttaggggcag atgtggagaa ggccttgaca aatctcggtg
    26221 aagttttcta cagtccgcag gacatttata ctaagatgcg agctggggat tttgaaatgg
    26281 ctgactttga agcccatggc aagacctaca aaaacagctt tgtgacctat gagaatttct
    26341 accaaaacca tgaggatgct gaggttcgtg agaaatcctt ccgttccttc tcagagggac
    26401 ttcgtaagca ccaaaatacg gctgcagcag cctatctggc tcaggtcaag tctgaaaaac
    26461 tcttggctga tatgaaggga tacgactctg tctttgacta tcttctagct gaacaagaag
    26521 tggaccgtgc catgtttgac cgccagattg acctcatcat gaaggacttt gcaccagtcg
    26581 ctcagagata cctcaagcat gttgccaagg taaatggtct tgaaaagatg acctttgcag
    26641 actggaaatt ggacttggac agcgccctga atcctgaagt gactattgac gatgcctatg
    26701 atttggtcat gaagtcggta gaacctttgg ggcaagaata ttgtcaggaa gttgctcgtt
    26761 accaagaaga gcgctgggtg gactttgctg ctaacagtgg caaggattcc ggtggttatg
    26821 cggcggaccc atatcgcgta cacccttatg tactcatgag ctggacaggc cgtttgagcg
    26881 atgtctatac cttgattcat gaaatcgggc attctggtca attcatcttt tcagacaatc
    26941 atcaaagtta cttcaatgcc catatgtcga cctactatgt tgaagcaccg tcaaccttca
    27001 atgaattgct actcagtgat tacttggaga accagtctaa tgacccacgt caaaaacgct
    27061 tcgctctggc tcatcgcttg acagacacct acttccataa ctttatcacc catctcttgg
    27121 aagccgcctt ccagcgtaag gtgtatacat tgattgaaga aggggagacc tttggagcaa
    27181 gcaagctcaa cagcattatg aaggaagttt tgacggattt ctggggagat gctattgaaa
    27241 ttgacgatga tgcaactctg acttggatgc gccaagctca ctactatatg ggcttgtata
    27301 gttacactta ctcagcagga ctagttatct cgactgctgg ttaccttcat ctaaaacatt
    27361 ctgaaactgg agctgaagac tggctcaatc tcctcaaatc aggtggtagc aagacaccac
    27421 ttgagtcagc catgattatc ggtgctgata tttcaacaga caaaccactc cgtgatacca
    27481 tccaattctt gtctgacaca gttgaccaga ttatctccta tagtgctgag ttgggagagt
    27541 aggggaatag aaaaattttt tagaatgatg tttatgggct tgttaagcgt cattctattt
    27601 gtcttagttg tagctatttt caaaaatgtc gttgaaggtc gtgatgttaa atttgaactt
    27661 actgtagaac tggtattgat agttatttac gtcattttat atcagattgt atttaattga
    27721 gaattcaata ttgagtcatt taagactgcc tttttgaaca gttgctagaa atgtagaggt
    27781 attgaccatg tatcaagatt tactaagaaa aatagcagaa gaaaaaccaa attataacca
    27841 ggaagaaatc cagtggttgt ttgatcattt gggaaatcct tctccagaaa ttcgtgatga
    27901 ccttgttttt acaagctttg ctagagggat tcaggaagag ctatttacac aggagcaatt
    27961 tcatttcatt gctgaggtgg tcttagctga tggagggtta gataaagaga ttgataaggt
    28021 aggcttgtca acacttgaac gttcttttag ggcacttatt tatgcaaatc tcttgtctgc
    28081 agatgccaac cagcaatcgg ttttttatca ggaattaaat gcaggatttc gtaatgtcct
    28141 tttaaatcaa ggcttgcact atctttcaaa agaaaaggat acaacaggtt tctcaagtca
    28201 gtatggttgg gttcacgctt ttgcacatgg agccgattta ctgacagagg tggtttgtca
    28261 tccagacttt cctaaaaaca gagttcatga agtatttgat atacttggcc aactatttaa
    28321 aagaatgtcg attcgcttta cagatgatga ggattggcgt ttagcaagag tgatctatga
    28381 acctatttta caagggaagt tggagcaaga acaagtagct tcttggataa aaactgttga
    28441 ttttccgata gaagaaaggg aggattttta caaattttcc aactttagat cctgtctggt
    28501 ggaagtctat gtccaacttg accagagaaa tagtttacaa gatgagttga aagaagctat
    28561 ccagtctttt caatactaga gattagctaa tagttctatg attttcaaaa aatttccaat
    28621 caattttctt gaaacccttt cctacttttg atagactagt atctagtttt tgaaaaaagg
    28681 agaaagaaaa tgaaaaaatt tgttgctgag ttaatcggta cgttcatgct tgtgttcgtt
    28741 gggacaggag ctgttgtttt tggaaatggt cttgatggcc ttggtcacct tggaatcgcc
    28801 tttgcctttg gtttggcaat cgtggtggca gcctactcaa tcggaactgt ttcaggtgct
    28861 cacttgaacc cgactgtttc gattgctatg tttgtaaaca aacgtttgtc atcttcagaa
    28921 cttgtaaact acatccttgg tcaggttgtt ggagctttca tcgcttctgg cgctgtcttc
    28981 ttcctcttgg ctaactcagg tatgtcaact gctagtcttg gtgaaaatgc cttggcaaac
    29041 ggtgtcactg tctttggtgg tttcttgttt gaagtcatcg caactttctt gtttgtattg
    29101 gttatcatga ctgtgacttc agaaagcaag ggcaatggcg cgattgctgg tttggtaatc
    29161 ggtttgtcat tgatggcgat gattcttgtc ggattgaaga ttactggact ttcagtaaac
    29221 ccagctcgta gcttggcacc agctgtcttg gtagacggcg cagcccttca acaagtttgg
    29281 attttcatcc ttgcaccaat cgctggtgga gttcttgcag cccttgttgc aaaaaatttc
    29341 cttggaacag aagaataatt gaaactcaaa aagccttgct cctcatcttg aggaacaggg
    29401 ctttttcgta tgatactctt cgaaaatctc ttcaaaccac gtcagcttca ccttgccgta
    29461 ggtatggtta ctgacttcgt cagttctatc tgcaacctca aaacagtgtt ttgagcaacc
    29521 tgcggctaac ttcctagttt gctctttgat tttcattgag tatgacttta gcggttgtca
    29581 attttctctg gataaaggtc gtgttggaag aggcgttgtt ctgccaagcc ctcatactta
    29641 gttccttgct taccgtagtt gtagtagggg tcgattgaaa tgccaccgcg cggagtgaat
    29701 tttccccaga cttctaaata gcgagggtct agcaagttga ccaagtcttt cccgatggtg
    29761 ttgatacagt tttcgtggaa atctccgtgg tttcggtagc taaatagata tagtttgagg
    29821 gattttgact cgacacagag cttgtcagga atgtaggaaa tatgaatcgt cgcaaagtct
    29881 ggctgagcag tgatttgtcc cagcagagac atatcgagga tatggtgacg aatgccctgt
    29941 tccttagcga tttctctagt aatttgaatt tcgaggtgat gacgttggcc gtaggcaaag
    30001 gtgacagctt cgactgtttc atagtgttgc atggcccaga aaaggcaggt tgttgaatct
    30061 tgaccaccac taaagacgac caaggctgat tgatgtttca tagtactcct tccaaaatgg
    30121 gaaatgttca gagcacgcaa aaagctccca ttagggagct aaaaaatacc aaatcgagtt
    30181 tttttagcga tggcatatcc caaacatcgt aatattctac ttatatagta aaatgaaata
    30241 agaacagga
//
LOCUS       DBERXF010000027        28095 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.27, whole genome shotgun sequence.
ACCESSION   DBERXF010000027 DBERXF010000000
VERSION     DBERXF010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 28095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28095
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.27"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            553..1731
                     /locus_tag="ACL8JK_001326"
     CDS             553..1731
                     /locus_tag="ACL8JK_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ryptide export MFS transporter"
                     /protein_id="HGS1786201.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQIFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYIAESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            2045..2176
                     /locus_tag="ACL8JK_001327"
     CDS             2045..2176
                     /locus_tag="ACL8JK_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGS1786202.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2197..3747
                     /gene="dltA"
                     /locus_tag="ACL8JK_001328"
     CDS             2197..3747
                     /gene="dltA"
                     /locus_tag="ACL8JK_001328"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGS1786203.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3744..4988
                     /gene="dltB"
                     /locus_tag="ACL8JK_001329"
     CDS             3744..4988
                     /gene="dltB"
                     /locus_tag="ACL8JK_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGS1786204.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            5002..5241
                     /gene="dltC"
                     /locus_tag="ACL8JK_001330"
     CDS             5002..5241
                     /gene="dltC"
                     /locus_tag="ACL8JK_001330"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGS1786205.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5234..6502
                     /gene="dltD"
                     /locus_tag="ACL8JK_001331"
     CDS             5234..6502
                     /gene="dltD"
                     /locus_tag="ACL8JK_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGS1786206.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6657..7097
                     /gene="adcR"
                     /locus_tag="ACL8JK_001332"
     CDS             6657..7097
                     /gene="adcR"
                     /locus_tag="ACL8JK_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HGS1786207.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            7097..7801
                     /locus_tag="ACL8JK_001333"
     CDS             7097..7801
                     /locus_tag="ACL8JK_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGS1786208.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7794..8600
                     /locus_tag="ACL8JK_001334"
     CDS             7794..8600
                     /locus_tag="ACL8JK_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGS1786209.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8610..10115
                     /gene="adcA"
                     /locus_tag="ACL8JK_001335"
     CDS             8610..10115
                     /gene="adcA"
                     /locus_tag="ACL8JK_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HGS1786210.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(11275..12048)
                     /locus_tag="ACL8JK_001336"
     CDS             complement(11275..12048)
                     /locus_tag="ACL8JK_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS1786211.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPNQKLLDAVELFDGEWVSDIQ"
     gene            12224..13627
                     /locus_tag="ACL8JK_001337"
     CDS             12224..13627
                     /locus_tag="ACL8JK_001337"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase family protein"
                     /protein_id="HGS1786212.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDVDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13742..14380
                     /locus_tag="ACL8JK_001338"
     CDS             13742..14380
                     /locus_tag="ACL8JK_001338"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HGS1786213.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            14392..14832
                     /locus_tag="ACL8JK_001339"
     CDS             14392..14832
                     /locus_tag="ACL8JK_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HGS1786214.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14825..15256
                     /locus_tag="ACL8JK_001340"
     CDS             14825..15256
                     /locus_tag="ACL8JK_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1786215.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            15247..15717
                     /locus_tag="ACL8JK_001341"
     CDS             15247..15717
                     /locus_tag="ACL8JK_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS1786216.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15742..16515
                     /locus_tag="ACL8JK_001342"
     CDS             15742..16515
                     /locus_tag="ACL8JK_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS1786217.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16512..17312
                     /locus_tag="ACL8JK_001343"
     CDS             16512..17312
                     /locus_tag="ACL8JK_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS1786218.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17371..19665
                     /locus_tag="ACL8JK_001344"
                     /pseudo
     CDS             17371..19665
                     /locus_tag="ACL8JK_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase N-terminal domain-containing
                     protein"
     gene            19675..22791
                     /locus_tag="ACL8JK_001345"
     CDS             19675..22791
                     /locus_tag="ACL8JK_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 98 C-terminal
                     domain-containing protein"
                     /protein_id="HGS1786219.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKEDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNDYEVFTQHIDSLESNNLSIDLKGLKGKKVRISLRSAGIPLSLA
                     EVEVYTYK"
     gene            22874..24640
                     /locus_tag="ACL8JK_001346"
     CDS             22874..24640
                     /locus_tag="ACL8JK_001346"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HGS1786220.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRS
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYCACQLLGPLHK"
     gene            24786..25937
                     /locus_tag="ACL8JK_001347"
     CDS             24786..25937
                     /locus_tag="ACL8JK_001347"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGS1786221.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            26082..26966
                     /locus_tag="ACL8JK_001348"
     CDS             26082..26966
                     /locus_tag="ACL8JK_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGS1786222.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(27003..27161)
                     /locus_tag="ACL8JK_001349"
     CDS             complement(27003..27161)
                     /locus_tag="ACL8JK_001349"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786223.1"
                     /translation="MKIKEQTRKLATGCSKHRFEVVDKTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            27365..27616
                     /locus_tag="ACL8JK_001350"
     CDS             27365..27616
                     /locus_tag="ACL8JK_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HGS1786224.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            27604..27894
                     /locus_tag="ACL8JK_001351"
     CDS             27604..27894
                     /locus_tag="ACL8JK_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGS1786225.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEYKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
BASE COUNT         8851 a         4602 c         5955 g         8687 t
ORIGIN      
        1 acttaaacgt gctatatcaa aaccagtcct ggaaaaacgt ggactggttt cgtgtttgga
       61 ttattacctt gaacgacatg cgttaaaagt tagttgaacc gccgtatgcc gaacggcacg
      121 tacggtggtg tgagaggggc tagagattat cccctactcg attaactccc ctgaaattta
      181 ttttaattat gcaaatttca cgtatttttg atgctgagac gacgatcctg ggaacttttc
      241 agatattttt ttgactatct aaatctatca ttagaaaagc ttagagcgcc aaaggatttg
      301 agcgtttttc tgatttttaa gactttttcc agtctctttt tcgattgaag atgtaattat
      361 tctactaact aactaacttc ttagtactag ccaacaacga taatcataat tcctcctaaa
      421 attaggaata ataaaggcaa tagtttttgt tttttcatgt aaaaaacctc acttttgttt
      481 tctgctattt tatgctaaaa tattaaaaat caaatttaat tccaaagttt gtaactaaag
      541 ggggagcgct acatgtctaa ttcatttgtc aagttgttag tctctcaatt atttgcaaat
      601 ttagcagata ttttctttag agtaacaatc attgctaaca tatacattat ttcaaaatca
      661 gtaattgcca catcactagt tcctatctta ataggaatat cctcttttgt tgcgagtctt
      721 ttagttccgt tggttactaa aaggttagcg ctaaataggg ttttatcttt atctcaattt
      781 ggaaagacta tattattggc gatactggta ggaatgttta ccgtaatgca atccgtagcg
      841 cctttggtga cctatctatt tgttgttgca atttccatac tagatggttt tgcagcaccc
      901 gtttcctatg ctattgtgcc acgctatgcg accgatttgg gtaaggctaa ttcagcctta
      961 tcaatgactg gtgaagctgt tcaattgata ggttggggat taggtggact cttgtttgca
     1021 acaattggtc tgttacctac cacgtttatc attttagtct tgtatatcat ttctagcttt
     1081 ctgatgttat ttcttcctaa cgctgaagtg gaggtgttag agtcagaaac taatcttgaa
     1141 attttgctca aaggttggaa gttagttgct agaaatccta gattaagact ttttgtatca
     1201 gcaaatttat tggaaatttt ttcaaatacg atttgggttt cttccattat acttgttttt
     1261 gtaacggagt tattaaataa aacggaaagt tactggggat attctaatac agcatactct
     1321 attggtatta taattagtgg cttaattgct tttaggctat ctgaaaagtt ccttgctgct
     1381 aaatgggaaa gtattctttt tcctcttgta gctatggcaa tagtgacact gactattcta
     1441 tattttccaa acgcacagat atttttatta ttttcagctt tagttggtat gttatcgcaa
     1501 ctaaaagaag ttcctgaaag tgtatttctt caggaaacag tagaggaaaa tcatttagtt
     1561 aatgtctatt ccgttcttga agtgatttct acattagcat tttcagtatt tgttttgcta
     1621 atgagctata ttgctgagag ttttggtatt agcatcagtt tttggctatc agccatttgt
     1681 ctgatgatag aagctatttt aatttatatc agacgagatt attttaaatg agagagtggt
     1741 taaaaagtct ttaaaaatca gaaaagcgca tagtatcagg tgttgaaaaa acttgatatt
     1801 gtgtgtttta ttatgggaag atttacttca ttgtctcctg aaatggagtt ttgaagcagg
     1861 atcactctat ttgaaaatat acatagaaaa actgtataat ccttaaaata agctgaaatc
     1921 tattggaaac atacggtaaa caattgaaaa gatactatat aaagtggtac aatggtagaa
     1981 aaataagcta gtaagaatca ctcttatttt agcgaaaaat tacagaaatg aatggttttt
     2041 cttgatgaaa cagagaaaag aattgtacct ctttcttggt cggacagcct tgtattttct
     2101 tatctttcta gggctgcttt acttctttag ctatcttggt cagggtcaag gaagctttat
     2161 ctataatgaa ttttaacttg aaggagaatc cctattgtgt caaataaacc aatagcagat
     2221 atgattgaaa ccattgagca ttttgctcag acacagccta gctatcctgt ctataatgtt
     2281 ttggggcagg aacacactta tggcgattta aaggctgatt cggatagttt ggctgcagtc
     2341 attgaccaac taggcttgcc tgagaagtct cctgtggttg tttttggtgg ccaagaatat
     2401 gaaatgttgg caacctttgt agcgctgact aagtcaggtc atgcctacat tccaattgat
     2461 agccattcgg ccttggagcg agtttcagct attttagaag tagcagagcc aagcttgatt
     2521 attgccattt cagcctttcc cttggagcag gtttctacac caatgataaa tctagctcag
     2581 gttcaagaag cctttgccca agggaataac tatgaaatca cgcatccagt caagggagat
     2641 gataattact acattatctt tacttctggt acgactggta agcctaaggg agtgcagatt
     2701 tcacatgata atctcctcag ctttacaaac tggatgatta cggataagga atttgcgaca
     2761 ccgagtcgtc cgcaaatgct ggcacagcca ccttattctt ttgacttgtc tgtcatgtat
     2821 tgggcaccga ccttggcact tggtggtacg cttttcactc ttccttcagt catcactcag
     2881 gactttaagc aactctttgc ggctatcttt tcattgccaa tcgctatctg gacatcaaca
     2941 ccatcctttg cagatatggc catgttgtct gaatacttca acagtgagaa aatgcctgga
     3001 atcacgcatt tctactttga tggtgaagaa ttgacggtca aaacagctca aaaactgcgc
     3061 gagcgtttcc caaatgcccg tatcatcaat gcttacggcc caacagaagc gacagtagct
     3121 ctgtcagcag ttgccgtgac agacgagatg ttagcgactc tcaaacgcct accaatcggc
     3181 tataccaagg ctgattctcc aacctttatc attgacgagg aaggaaataa actgccaaat
     3241 ggcgaacagg gagaaatcat tgtttctggg ccagctgttt caaaaggtta tatgaacaat
     3301 cctgaaaaaa cagcagaagc cttctttgag tttgaaggtc tgccagccta tcacacaggc
     3361 gatgtgggaa ccatgacaga tgagggcttg cttctctacg gcggacgcat ggacttccag
     3421 attaagttta acggttaccg cattgagtta gaagatgtct ctcaaaacct caacaagtct
     3481 cgctttatcg aatctgctgt cgcagtaccg cgctataaca aggaccacaa ggtacaaaat
     3541 ctattggctt atgtcatctt aaaagacggt gttcgtgagc agtttgagcg agatatcgat
     3601 attaccaagg ccatcaagga agacctgaca gacatcatga tgtcctacat gatgccatct
     3661 aaattccttt accgagacag tttgccactg actccaaatg gaaagattga catcaaagga
     3721 ttgattaacg aggtgaataa gagatgatgg agttttttca acagcttcct catttagagc
     3781 catatggcaa tcctcagtat tttgtttatg tgattgctgc aaccttgccc atctttatag
     3841 gcctcttttt caagaaacgc tttgcctggt atgaagtgtt ggtaagtctc ttctttattg
     3901 tcaccatgtt ggtgggtgga aagaccaatc aactagctgc cttgggtatt tacctttgct
     3961 gggaaatatt gctcctgctt ttctacaagc attatcgaaa aagcaaggat ggcaagtggg
     4021 tcttctactt agttagtttt ctgtccctac ttccgattat ctttgtcaag gtgcaaccag
     4081 ctatcaatgg aacgcagtct ttgcttgggt tcttgggaat ttcttacctg acctttcgtt
     4141 cggttgggat tatcatcgag ctgagagatg gagtgattaa ggattttacc ctctgggaat
     4201 tcctccgttt ccttctcttc atgccaactt tctcgagtgg tccaatcgat cgttttaagc
     4261 gatttaatga aaattatcag gccattcctg agcgagatga gttgatggat atgctggatg
     4321 aatctgtccg ctatatcatg cggggctttt tgtataagtt tatcctagct catgttttag
     4381 gagagacctt actacctcct ctgaagaatt tagccttgca gtcaggtggc ttctttaatc
     4441 tctatgcctt ggcagttatg tatacttttg gtctggagct cttctttgac tttgcaggtt
     4501 attctatgtt tgctttggcc atctcaaact tgatgggaat ccgtagccct atcaacttta
     4561 acaagccctt tttatcaagg gatttaaagg agttttggaa tcgctggcat atgagtctgt
     4621 ccttctggtt ccgtgacttt gtctttatgc gaatggtgat ggtgttaacc agaaagaaag
     4681 tctttaaaaa tcgtaatgta acctcaagca tggcctacat tgtaaatatg ctgattatgg
     4741 gattttggca tggtgtgacc tggtactata tcgcctatgg actctttcat ggactaggct
     4801 tggtcatcaa tgatgcctgg gttcgcaaga aaaaaacgct caataaggaa cggaaaaaag
     4861 cagggaaggc tgccctacct gagaatcgct ggattcagtt gcttggcatg gttgtcactt
     4921 tccatgttgt catgttgtca ttcttaatct tttctggatt cttgaataat ctatggttta
     4981 aaaaataaaa ggaaataaaa tatggatatc aaatcagaag ttattgaaat tattgatgag
     5041 ttgtttatgg aagatgtttc tgacatgatg gatgaagatc tttttgatgc aggtgtcttg
     5101 gatagtatgg gaacggttga gttgattgtg gagattgaga accgttttga cattcgtgtc
     5161 cctgtaacag agtttggtcg tgacgactgg aatacagcta ataaaatcat agctggtatt
     5221 gtggagctac aaaatgctta aacgcttatg gatgatcttc ggaccggtct tgatcgctgg
     5281 tttgttggtt tttctgctca ttttctttta tcctactgag atgcatcata atctaggagc
     5341 tgaaaagcgt tcagcagtgg ctactactat cgatagtttt aaggagcgaa gtcaaaaagt
     5401 cagagcacta tctgatccaa atgtgcgttt tgttcccttc tttggctcta gtgaatggct
     5461 tcgttttgac ggtgctcatc ctgcggtatt agctgagaaa tacaatcgtt cctaccgtcc
     5521 ttatctttta ggacaggggg gagctgcatc gcttaaccaa tattttggaa tgcaacagat
     5581 gttaccacag ctggagaata aacaagttgt gtatgttatc tcacctcagt ggttcagtaa
     5641 aaatggctat gatccagcag ccttccagca gtattttaat ggagaccagt tgactagttt
     5701 tctgaaacat caatctgggg atcaggctag tcaatatgca gcgactcgct tactgcaaca
     5761 gttcccaaac gtagctatga aggacctggt tcagaagttg gcaagtaaag aagaattgtc
     5821 gacagcagac aatgaaatga ttgaattatt ggctcgtttt aatgaacgcc aagcttcctt
     5881 ttttggtcag ttttcggtta gaggctatgt taactacgat aagcatgtag ctaagtattt
     5941 aaaaatcttg ccagaccagt tttcttatca ggcaatagaa gatgttgtca aagcagatgc
     6001 tgaaaaaaat acttccaata atgagatggg aatggaaaat tatttctata atgagcagat
     6061 caagaaggat ttgaagaaat taaaggattc tcagaaaagc tttacctatc tcaagtcgcc
     6121 agagtataat gacttgcagt tggttttaac acagttttct aaatctaagg taaacccgat
     6181 ttttatcatt ccacctgtta ataaaaaatg gatggactat gctggtctac gagaggatat
     6241 gtaccaacaa acggtgcaga agattcgcta ccagttagaa agtcaaggtt ttaccaatat
     6301 agcagatttt tctaaggacg gcggggagcc tttctttatg aaggacacca ttcaccttgg
     6361 ttggttgggt tggttggctt ttgacaaggc agttgatcct ttcctatcca atcccacacc
     6421 agctccgact taccatctga atgagcgctt tttcagcaaa gattgggcga cttatgatgg
     6481 agatgtcaaa gaatttcaat agataatata atatagaaga gttcaagaat gaaactagtt
     6541 ttcacgtttt ttcttgactc tttttttgct tgtgatataa ttaactggta aacaaaatgt
     6601 caaagaatag tatttttctc ttaaaaaaga gaagtctaaa aggaaaggag tcagatatga
     6661 gacagctagc aaaggatatc aatgcttttt tgaatgaggt gattttgcag gcggaaaatc
     6721 agcatgaaat cctaataggt cattgcacta gcgaggtggc cctgaccaat actcaggagc
     6781 atatccttat gctcttgtca gaggaatctt taacaaattc agaattggcc cgtcgtctca
     6841 atgtcagtca ggcggcagtt accaaggcca ttaagtcttt ggtcaaggaa gggatgttgg
     6901 aaacatctaa agattctaaa gatgcgcgtg tgatttttta tcagttgact gacttggctc
     6961 gtccaatcgc tgaggagcac caccatcacc atgagcatac acttttaacc tatgaacaag
     7021 tggcgactca gtttactcca aatgaacaaa aagtgattca gcggtttttg actgctttag
     7081 taggagaaat caaataatga gatatattac ggtagaggat ttgtccttct attatgataa
     7141 ggagcctgtt cttgaacata tcaattatag tgttgatagt ggggaatttg ttaccttgac
     7201 tggggaaaat ggagcggcta agacgacgct catcaaggct agtcttggaa ttctgcaacc
     7261 acgcattgga aaggtggcta tttcaaagac aaatacgcaa ggtaagaaat tgagaatagc
     7321 ctatcttcct caacaaattg ccagttttaa tgctggtttt ccaagtacgg tctatgaatt
     7381 tgtcaagtcg ggtcgctatc cgagaaaagg ctggttccgt cgtttgaatg ctcatgatga
     7441 ggagcatatc aaggctagtc tggactcagt tggcatgtgg gaacatcgag acaaacgctt
     7501 ggggtctcta tctgggggac aaaagcagcg agcggtgatt gcgcgtatgt ttgcttctga
     7561 ccctgatgtg tttatcctag acgagccgac aacggggatg gatgcaggaa gtaaaaatga
     7621 attttacgaa ctcatgcacc acagcgccca tcatcatggc aaggctgttt tgatgattac
     7681 ccatgaccct gaagaagtta aggattatgc ggatcgcaat attcatctag tccgtaacca
     7741 agactcgcca tggcgttgtt tcaatgttca tgagaatggc caggaggtgg gccatgctta
     7801 gtttattatc ttacgacttt atacaacgcg cctttttggc ggttattgct atgagtcttt
     7861 tctcaccggt attgggaacc ttcctcatct tgcgtcgtca gagtttgatg agtgataccc
     7921 ttagccacgt ctcactttca ggtgtagcct ttggtctggt tttggggatt tctccaactg
     7981 tttctactat tgccattgtc ttgattgcgg cggtctttct ggagtatctc cgtacggttt
     8041 acaagagctt tatggaaatc gggacagcta tcctcatgtc aacaggtctg gctgtttctc
     8101 tgattgtcat gagcaagggt aaaagctcga gttcaatgag tttggaccaa tatctctttg
     8161 gttcgatcgt gactatcagt gaagaacagg tcatttccct ctttgtcatt gcggcggttg
     8221 ttttgatttt gacctttctc tttcttcgtc ctatgtatat cttaactttt gacgaagata
     8281 cggcctttgt ggatggcttg ccagttcgta ccatgtccat tctttttaac atggtgacag
     8341 gggtggctat tgcccttatg attcctgcag caggagctct tctggtatcg accattatgg
     8401 tcttgccagc tagtattgcc ctgcgtctgg ggaaaaactt taaatcggtt atgctgcttg
     8461 ccagtgcgat tggctttttg ggaatggtag caggacttta catttcctac tatgcagaaa
     8521 cacctgcaag tgcaagtatt accattattt ttgtaactgt ctttatacta atcagtttag
     8581 taagacgttt tatcaaatag gagacgaacg tgaaaaaaat tagcttatta ctagccagtc
     8641 tatgtgcctt gtttttagtg gcttgttcca atcaaaaaca ggcagatggt aaactcaata
     8701 tcgtgacaac cttttaccct gtctatgaat ttaccaagca agttgcagga gatacggcta
     8761 atgtagaact cctaatcggt gctgggacag aacctcatga atacgaacca tctgccaagg
     8821 cagttgccaa aatccaagat gcagatacct tcgtttatga aaatgaaaac atggaaacat
     8881 gggtacctaa attgctagat accttggata agaaaaaagt gaaaaccatc aaggcgacag
     8941 gcgatatgtt gctcttgcca ggtggcgagg aagaagaggg agaccatgac catggagaag
     9001 aaggtcatca ccatgagttt gacccccatg tttggttatc accagttcgt gccattaaac
     9061 tagtagagca cattcgtgac agcttgtcag cagattatcc tgataaaaaa gagacctttg
     9121 agaagaatgc agctgcctat atcgaaaaat tgcaagcctt ggataaggct tacgcagaag
     9181 gcttgtctca agcaaaacaa aagagctttg tgactcaaca cgcagccttt aactatcttg
     9241 ccttggacta tggactcaaa caagtcgcaa tctcaggact ttctccagat gcagagccat
     9301 cagctgctcg cttggcagaa ttgacagagt atgtcaagaa aaataaaatc gcctatatct
     9361 attttgaaga aaatgcctca caagcccttg ctaacacact ttcaaaagaa gcaggtgtca
     9421 aaactgatgt cctcaatcct ttagaaagtc tgacagaaga ggacaccaag gctggagaaa
     9481 actacatttc cgtgatggag aaaaacctca aggctttgaa acaaacaaca gaccaagaag
     9541 gcccagcaat cgaacctgaa aaggcagagg ataccaagac agtccaaaat ggttacttcg
     9601 aggatgcagc tgtcaaggac cgcaccttga gtgactatgc aggtaactgg caatcagttt
     9661 atcctttcct tgaagacggc acgtttgacc aagtctttga ctacaaggct aagttgactg
     9721 gtaagatgac ccaggctgag tacaaggctt actatacaaa aggctatcag acagatgtga
     9781 ctaagattaa cattactgat aatactatgg aatttgttca aggtggacaa agcaagaaat
     9841 acacttacaa gtatgtcggt aagaaaattt tgacttacaa gaaaggcaat cgtggcgtgc
     9901 gttttctctt tgaagccaca gatgctgacg ctggacaatt caagtatgtt cagtttagtg
     9961 accacaatgt tgccccagtt aaggcagaac atttccatat cttctttgga ggcacaagcc
    10021 aagaagccct ctttgaagaa atggacaact ggccaaccta ctacccagat aacctatctg
    10081 gccaagaaat cgcccaagaa atgttggcgc attgatgaga aatcgactag ttcataagag
    10141 ctagtcggtt ttttgatact agatggctaa cttcattata gacctttcag aactttaaac
    10201 aataaataaa actcttgaaa tatctgggct tatatgctag aatgtagtta gtgtataagg
    10261 ttcattagaa caccaaagcc cctaactagt gccatagtta agggcttttt tgacgtatct
    10321 tagcgattta acgggtgttt ataggctagt cattcggtct acttcttacc atctagccat
    10381 ttgcagacga aatacaagat aattccagct ataacatctg ctataatagt aagagcaagc
    10441 tctggtataa ggctcattag tttcacctcc tctcacgaac cgtaaggaac gtaatcggta
    10501 accgatgaca aaaatagtat atcacactac attcaggtca tcaaccttac ttaatgcttg
    10561 aactattgta gattatatgc tagaatgtag ttaattgata aggttcatta gaacaccaaa
    10621 gcccctaact atggccgtag ttaagggctt ttttgacgta tcttagcgat ttaacgggtg
    10681 tttataggct agtcagtcgg tctactcctt actatctagc catctgcaga cgaaatacaa
    10741 gataattcca gctataacat ccgctataat agtaagagcg agctctatga taaggctcat
    10801 tagtttcacc tcctctcacg aacccatagg aacgtaatcg gtaaccgatg acaaaaatag
    10861 tataccacaa tacatttaga tcatcaaggt cacttaattc ttgaaatatc agatctaaga
    10921 gaaaaatctt taaaatcaga aaaacgcata atatcaggtg tgcaaaaact tgatactatg
    10981 cgttttattg tgggaaggtt tactccattt tctcctgaaa ttgagttttt gtccagcctc
    11041 tgtttttagg gttgctaaga aaataatgtc atgtggtgaa tatttgtaaa tcagtcagca
    11101 gacagaacga tactcttcga aaatctcttc acatcatgtc agctttgtct ttccgtatat
    11161 atgtgactga cttcatcagt tctatctaca acctcaaaac agtgtttcga gctgacttca
    11221 tcagttttca aatctgtact gtgagcaagc tgagactagc ttcctatttg atttttattg
    11281 aatatcagaa acccattctc catcaaataa ttcgactgcg tctaataatt tttgatttgg
    11341 caaggtgtca gaaataaagg ttgtgtattt ggagagggga ttaattttaa aaaatccagt
    11401 cttgtaaaat ttagaactat caatcagtaa gatggtttca tgggctttgt caataatatt
    11461 cttttttgaa atagcttggc tgagagaagc ttcataaaca tattggtcat caatacctct
    11521 tgctgaacaa aatgctaaat cgatattaaa atgatctaat aaagaatttt ccttatcata
    11581 gttgaccacg gaacaggatt gatgtttgac ctcgccagat gtgataaaga ttttggagct
    11641 atctttaaca gtttcagata gggtttgtgc agtatgtaaa ccatttgtaa aaataatcaa
    11701 attatcaagt tcagaaagat agggacaaag ttcgtagaca gtagtactag aatctagata
    11761 gatacacata ccagaccgaa taaagtcttt agcgagacta gcgattagtc ttttttgcct
    11821 agtactttct ccttcccgta tttgatgaga aagttcaatt gtgttcatag aggacagggt
    11881 cacgtatccg tgctttcttt tgataagacc ttgattttct aagaaaatta aatcacgacg
    11941 taaggtactt gtgctggaga aagtgatttc tgccagctct tttacggcaa ttcttttttt
    12001 ctttttgatg atttcaatca attcaagtac acgttcatct tttatcataa gctcctccta
    12061 atttatcatt tcaactatat tatagcacaa attggaggaa tgtgaattat ttttatgaat
    12121 attgggttaa catttgaaca ttattcaagt aagcgttcac atattgaaaa aataaaacgt
    12181 ggggattata ataaagttaa tcaaggacga agagagaaga aaaatggaag cggttttagc
    12241 aatagattta ggtgcgactt ctggaagagc aatcgttggt tacctttctg aaaataaact
    12301 agtaatggaa gaaataaatc gcttttctaa tctacctatt agagtaaaag ggcatttatc
    12361 ttgggatgtt gactttctac tagctaaaat tcttgaaagt atccgcttgg ctaatactag
    12421 ttacaagatt ttatctatcg gtattgacac atggggagtt gattttggac tgattgataa
    12481 tgaaggtaag ctgttatcac aacctgttca ttatcgtgat gaaagaacaa agggagtgtt
    12541 aaaggaaata tctgaaatga ctgaattaga aaaactgtat tcagagacag gaaatcagat
    12601 tatggagata aataccttgt ttcaactctt taaggcacgt caagaatctc ctgactcttt
    12661 ctataagacc aataagattc ttttaatgcc agatttgttt aattatctct tgacaggtaa
    12721 gtttgctaca gaaaaaagca ttgcttcaac aactcaatta tttgatccta ggagtcaaaa
    12781 ctggaatcag aatatcttaa aactatttga attggattca tctttacttc ctgagattgt
    12841 ttcagaggga aatgttcttg gaaggataaa aaaggagtat ggtttaggcg atattcctgt
    12901 tgtgaatgtt tgtagtcatg atacagcaag tgcgattgtc tcagtaccta agacagaagg
    12961 tagtttattt atttcatcag gtacttggtc tttggttgga gtggaactta cttcaccgat
    13021 tcttactacc gaatccttca gttatggatt tacaaatgaa gtcggtaaag atggagagat
    13081 tacatttctg aagaattgta cagggttgtg gatcatagag gaactaagac gttcatttga
    13141 acgaagaggg aaagcctatt cttttgatga tattaggaca atggtggaga aagaaaaaga
    13201 aaatcttcct ctgattgata ctgaatcaac agaatttgca acagaatctg atatgcacaa
    13261 gactttgaca gaatatctag cttatcatca tgaaactaga gagtggacag atggacaact
    13321 atttaagatt gtttatgaaa gcctagctga aacgtatagg aaagcgatag agttattaga
    13381 agaactaact cataaggttt ataagaggat atatgtgatt ggaggaggtg ctagagccag
    13441 ttactttaac caaatgattg ctgatagaac tggtaaagag gttcttacag gttcgactga
    13501 gggtacagct gtggggaata ttgttgtgca gctcatagct atgggacaat taaaagggat
    13561 ggaagaagct caccatgtta ttgaggagtt tctacaatta gagagttatt actcccaaaa
    13621 gaattaaaaa gattgagagt ttgtaaattt gcctccctcc cccttcttaa gttttgtaca
    13681 agaagggggg ataattggtg aattgaaaaa tatttagtgt tttgatatga ggaggacaag
    13741 aatgtcagat gtaaaacaag aattaattaa gtatggcaag aagctagtag aaacagattt
    13801 gacgaaagga acaggtggga atctcagtgt tttcgatcgt gaaaaacaat tgatggcaat
    13861 taccccgtcg ggtattgatt tctttgaaat caaagaatcc gatattgtag tgatggatat
    13921 taatggaaat gttgtagagg gagaacgctt gccatctagc gaatggtata tgcatttgat
    13981 tcaatatcaa actcgtgatg atatcgatgc aattatccat gctcatacaa cttatgcaac
    14041 agtattagct tgtctcagag aaccacttcc ggctagtcat tatatgattg cagtggcagg
    14101 gaaagatgtt cgggtagctg agtatgcaac atatggtacg aaagaattgg ctgtgaatgc
    14161 agctaaagca atggaaggtc gtagagcagt tttactagcg aatcatggaa ttttagcagg
    14221 tgcacaaaat ttattgaatg catttaatat tgttgaagaa gttgaatatt gtgcaaaaat
    14281 ttattgttta gctaagaatt ttggagagcc agtagttctt cctgatgagg agatggattt
    14341 aatggcagaa aaatttaaaa catacggtca gagaaaatag ggaggatatt aatgttaaaa
    14401 catataccga aaaatatttc tccagattta ttgaagactt taatggaaat gggacatgga
    14461 gatgaaatag tattagctga cgcgaattat ccttctgcct catgtgcaaa taagctaatt
    14521 cgttgtgatg gcgtaaatat tccagaatta ttagattcca ttctgtattt aatgccatta
    14581 gatagttacg tcgatagttc aattcagttt atgaacgttg tttcgggtga tgatattcct
    14641 aagatatggg gtacctatag acagatgatt gaaggtcatg gtacagatct taaaacgatt
    14701 acttatctta gaagagaaga cttttatgaa cgtagtaaga aagcttatgc tattgttgct
    14761 acaggagaaa cttcacttta tgctaatatt atccttaaga aaggagtagt tgttgaaaga
    14821 gaaaatgttt aatagaggaa ttttagttgc cagtcatggt aattttgcta gcggagctct
    14881 catgaccgca gaaatgtttg ttggtgagac aacaaatgat agagttagga cattaggttt
    14941 gatgcctgga gagaatattg tagagtttga acattatttt aaaaatcaag taaatgaact
    15001 gttagactca aatcaagagg ttatcgtttt gactgacttg attggaggaa gtcctaataa
    15061 tgtggctttg tcacggtttt taaatttgga ttcagttgat attgtaacag ggtttaatat
    15121 ccctctccta gtggaattaa tatcaagtta tgattcaaaa atcaatttag aagaaattgt
    15181 tcaaaatgct caaaatagtt tgtttaatgt taaacaacaa cttaacgtag aggaggaaga
    15241 ggatttatgt ctatagagtt tgttcgtatt gatgaccgtc tggtacatgg tcaagttgtc
    15301 actacgtggc taaaaaagta tgatattgag caagttatca ttgttaatga tcgcatctca
    15361 gaagataaaa cacgacaatc tattttaaag atttctgcac cggtaggttt aaaaattgtt
    15421 ttctttagtg taaaacggtt tgtggaagtt ttaaactctg tgccaataaa aaagagaaca
    15481 atgctgatat atacaaatcc aaaagatgtg tatgattcta ttgaaggaaa tttaaaattg
    15541 gagtacctca atgtaggaca gatgagtaaa acggaggaaa atgaaaaggt aacgggaggt
    15601 gtagctctag gtgaagaaga caaatattat tttaagaaaa tagttgataa gggaacgaga
    15661 gttgaaattc aaatggttcc taatgataaa gttacaatgt tggaaaaatt tttataaaaa
    15721 taatttaagg aggtacagta tatgctattc acacaagcat tactggtgac attagttggg
    15781 attattgcca ctattgacta taatggaccg ttatttatga ttcaccgtcc gttagttaca
    15841 agtgcaatgg ttggcttagt cttaggagat ttcacccaag gtgttcttat tggttcagct
    15901 cttgaattaa cttggctcgg tgtaacaggt attggaggtt acactccacc agatactatt
    15961 tcaggtgcga ttattggtac tgcatttggt attttatctg gtcaaggaga aactgctggt
    16021 atcgctatag cagttccaat tgcagttgct acccaacagt tggatgttct tgcaaaaact
    16081 ttagatgttt attttgtgaa aaaagctgat aatgatgcta aaaacggaga ttattcaaag
    16141 atcggttttt atcattattc aagtttggtt ttaatcacgt tatttaaaat tgtaccaatt
    16201 ttcctagcta ttatgcttgg aggggaatat gtggcagact tgtttgctaa ggttccacca
    16261 atcgttatgc agggacttaa ctctgcaggt gctttactac cttcaattgg ttttggtatg
    16321 cttttaaata tgatgctcaa gaaaaatatg tgggtattct tgttgattgg attcatttgt
    16381 tctgtgtatg gaggaatgtc aaccattggg atctcactag ttggtattgc ggtagcatac
    16441 ttctacgata tgattggaag taaaccacaa gaaacaactt caagtagtga tgttgaggag
    16501 gatcttgatc tatgatgaat aataaagtaa ctaaagttga acttaaaaaa gttttcaaac
    16561 gaagttttat gtatggttct tcatggaact atgagagaat gcagaaccta ggttttctat
    16621 atacaattct tccagtattg aaaaaactat acccagacaa agattcagct tctcctgcaa
    16681 tgaaacgtca ccttgagttt ttcaatactc atcaaacagc ggcaccattt attcttggag
    16741 ttacttccgc tatggaagaa caagaaggaa atgaaggtgc agcttcaatt actggtatta
    16801 aagttggctt gatggggcca ctggctggtc taggagatag tttgttctgg ctgacactag
    16861 ttcctatctg ttttagtatt ggtgcgtctt attctaaaga cggcggtgct ttaggtatct
    16921 ttatcgcctt aatattgttt aatattatta atattcctgt taaatatttc ggtttgaaat
    16981 atgggtatac taagggttct agtcttatcc aagaaaataa tacaaaagga acattgaatc
    17041 gcgttacgag tatggcgaca gcattagggc tagtactagt gggtggtttg attccatcaa
    17101 tggttggtat taattttgga ttagaattta agcaggggga acttgttatt tctgttcaag
    17161 aaatgattac aaaattaatt ccaggattta tccctatggc tttgacttta ttaatgtgta
    17221 aattaattag aaaaggaaag aatccggttg tactaatctt tagtgttatg gctattggag
    17281 ttatcctagt tgttttagga attttgaagt agtagaaagt gtggaggtgg tatttgggat
    17341 atcacctcca ttttggaaga gaggtaaaga gtgaaattat ggtataagaa agctgcctca
    17401 aattggaatg aagccttgcc gattgggaac ggtcatttag gtggtatgat ttatggttca
    17461 gctacaaaag aatgtattca actaaacgat gagactattt ggtatagagg aaagtcagat
    17521 agaaataatc cagactcact attgcatctt aaaaaaattc gggaatatct tttagatgga
    17581 gaaattcaga aagccgaaga attgataaag ttaacaatgt ttgctacccc aagagatcaa
    17641 agccactatg aattacttgg ggaactttac attgagcata tagatattca gtcttgtgct
    17701 ctttcattgt atgaaagaga gctagattta gatacagcta tttctaatgt tgtgtttgag
    17761 cctaatagtt gtaatttaca aataaaaaga gaatatttta cgagttttaa taagaatatt
    17821 ttatgttgcc gtatagtgtc atcagttcaa aacacattaa atttaaacat taatttgggt
    17881 agaaataaac ggtttaatga tgaagtatct aaactggatt caagtacaat tttaatgtcg
    17941 gcctctgctg gaggtagaaa aggtgttcag tttaaagtag tatgtcattc taaggttacg
    18001 gatggtgaag taagtgtatt gggagagaca atagttattc ggaatgctac agaggtattt
    18061 ctttatctca aatcaatgac ggattattgg ggaaatatag atatttcttc tcttcaggga
    18121 gaatttagta gtattgatta ctttacagaa aaagatgaac atgtaaaaaa atatcaggag
    18181 caatttaata gagttgattt taaactagac tatagtaaag attgtcttag cattccaacg
    18241 aatctacttc ttgaaaacac taaaaagtat agtaactact tgactaactt gttatttcat
    18301 tatggaagat atctgttaat atagtctagt caaccgaatg gtttacctgc caatcttcaa
    18361 ggaatatggt gtgatgaatt aaatccaatt tggggttcta aatatacgat taatattaat
    18421 actcaaatga attattggat ggtaggtcca tgtgatttac cagaagtaga atatccatta
    18481 tttgatatgc tcgaaagaat gagagaaccg ggaagactaa ccgctaagaa aatgtatgga
    18541 gctagaggtt ttacagcaca tcataatacg gatggttttg gcgatacggc tccccaatct
    18601 catgccatgg gggctgcaat ttgggtatta actattccat ggttatgtac tcatatttgg
    18661 gaacactatt tatatttcca agatgagcgt attcttacgg aacattttga aatgataaaa
    18721 gaagcatttc ttttctttga agattattta tttgaggtgg atggctactt gatgacaggt
    18781 ccaagtgtct caccggaaaa taaatatcgc ttaaaaaatg gtattgaagg aaatgcttgt
    18841 ctatcatcta caattgataa tcaaattcta agatattttt gtgattcatg cattggcatt
    18901 gcaaaacaat taggagacaa ttcggatttt attagtcgtg tgaaggagtt aaaaaagaaa
    18961 ctacctaaaa caaaaatagg tagtaatggg caaatccaag aatggttaga agattatgaa
    19021 gaagtagagc ctgggcatag acacatttca cctctatttg ggctttatcc ttataatgag
    19081 attgatattc ataaaactcc ggaattagca gaagcagcta aaatcactat caataggaga
    19141 ttatcaaacg ctaatttttt atcttcacag gagagggagc aagcgattaa taattggtta
    19201 gtaagtggtt tgcatgctag tacacaaaca ggttggagtg ctgcatggct gattcatttt
    19261 tttgcgagac tatatcaagg tgaacctgct tataaccaga ttaatggttt gttaaataat
    19321 gcgactcttg gcaatttatt tcttgaccat ccaccatttc aaattgatgg taatttaggt
    19381 ttggtgagtg gaatttgtga attattagta cagagccatc ataattggtt atcactaatt
    19441 ccagctttac cttctgcttg gtcagaagga gaagtgaaag gtttcagagt aagaggagga
    19501 tataaggtat cgtttgcttg gaaaaatggg gatataacat tcctaaaatt ggaaggagga
    19561 aacaaagatc aaaaagtaag agtaagaata tatggcaaaa atactgatgt acaaaatatt
    19621 gaattggtat ttaattcaga aaaaattatt gagttaaatt tttaggtata agtcatgaat
    19681 aaagaaaaaa taaaaagaaa attaatcaca atattgtttg tatgtattgg gatgttatgt
    19741 tttggattgt tagcaggagt taaggctgat aatcgtgttc aaatgagaac gacgattaat
    19801 aatgaatcgc cattgttgct ttctccgttg tatggcaatg ataatggtaa cggattatgg
    19861 tgggggaaca cattgaaggg agcatgggaa gctattcctg aagatgtaaa gccatatgca
    19921 gcgattgaac ttcatcctgc aaaagtctgt aaaccaacaa gttgtattcc acgagatacg
    19981 aaagaattga gagaatggta tgtcaagatg ttggaggaag ctcaaagtct aaacattcca
    20041 gttttcttgg ttattatgtc ggctggagag cgtaatacag ttcctccaga gtggttagat
    20101 gaacaattcc aaaagtatag tgtgttaaaa ggtgttttaa atattgagaa ttattggatt
    20161 tacaataacc agttagctcc gcatagtgct aaatatttgg aagtttgtgc caaatatgga
    20221 gcgcatttta tctggcatga tcatgaaaaa tggttctggg aaactattat gaatgatccg
    20281 acattctttg aagcgagtca aaaatatcat aaaaatttgg tgttggcaac taaaaatacg
    20341 ccaataagag atgatgcggg tacagattct atcgttagtg gattttggtt gagtggctta
    20401 tgtgataact ggggctcatc aacagataca tggaaatggt gggaaaaaca ttatacaaac
    20461 acatttgaaa ctggaagagc tagggatatg agatcctatg catcggaacc agaatcaatg
    20521 attgctatgg aaatgatgaa tgtatatact gggggaggca cagtttataa tttcgaatgt
    20581 gccgcgtata catttatgac aaatgatgta ccaactccag catttactaa aggtattatt
    20641 cctttcttta gacatgctat acaaaatcca gctccaagta aggaagaagt tgtaaataga
    20701 acaaaagctg tattttggaa tggagaaggt aggattagtt cattaaacgg attttatcaa
    20761 ggactttatt cgaatgatga aacaatgcct ttatataata atgggagata tcatattctt
    20821 cctgtaatac atgagaaaat tgataaggaa aagatttcat ctatattccc taatgcaaaa
    20881 attttgacta aaaatagtga ggaattgtct agtaaagtca actatttaaa ctcgctttat
    20941 ccaaaacttt atgaaggaga tgggtatgct cagcgtgtag gtaattcctg gtatatttat
    21001 aatagtaatg ctaatatcaa taaaaatcag caagtaatgt tgcctatgta tactaataat
    21061 acaaagtcgt tatcgttaga tttgacgcca catacttacg ctgttgttaa agaaaatcca
    21121 aataatttac atattttatt gaataattac aggacagata agacagctat gtgggcatta
    21181 tcaggaaatt ttgatgcatc aaaaagttgg aagaaagaag aattagagtt agcgaactgg
    21241 ataagcaaaa attattccat caatcctgta gataatgact ttaggacaac aacacttaca
    21301 ttaaaagggc atactggtca taaacctcag ataaatataa gtggcgataa aaatcattat
    21361 acttatacag aaaattggga tgagaatacc catgtttata ccattacggt taatcataat
    21421 ggaatggtag agatgtctat aaatactgag gggacaggtc cagtctcttt cccaacacca
    21481 gataaattta atgatggtaa tttgaatata gcatatgcaa aaccaacaac acaaagttct
    21541 gtagattaca atggagaccc taatagagct gtggatggta acagaaatgg taattttaac
    21601 tctggttcgg taacacacac tagggcagat aatccctctt ggtgggaagt cgatttgaaa
    21661 aaaatggata aagttgggct tgttaaaatt tataatcgca cagatgctga gactcaacgt
    21721 ctatctaatt ttgatgtgat tctatatgac aataatagaa acgaagttgc taagaaacat
    21781 gttaataatt tgtcgggtga atctgttagt ctagatttca aagaaaaagg agcaaggtat
    21841 attaaagtta aattactaac gagtggagtg cctttgagtt tagcagaagt agaggttttt
    21901 agagaatcag atggtaagca atctgaagag gatatagata aaataacaga agataaagta
    21961 gtctctacaa ataaggtagc tactcaaagt tcaaccaatt atgagggtgt agctgcttta
    22021 gcagttgatg gtaataaaga tggagattac ggacatcatt cggtgactca tactaaggca
    22081 gattctaacg cttggtggca ggtcgatctg ggagaagagt ttacggtttc taaagttgat
    22141 atttataata gaacagatgc cgaacctcag cgtttatcta attttgatgt tatttttcta
    22201 tcttcatcag gagaagaagt ttttagaaga cattttgata aagtagttga tggtttgtta
    22261 tctttaaaag taccttctgt aggggctaag ctagtcaaaa tagaattaaa atcagcagct
    22321 attccgttaa gtttagcgga agttgaagtc tatggttcaa agagaactcc gaagaaactt
    22381 tctaatattg cattaacaaa agaaactcga cagagttcaa cggattacaa tggtttttct
    22441 cgtctagcag ttgatggaaa taaaaacgga gattatggtc atcattcagt gactcatacc
    22501 aaagaagatt ctccttcatg gtgggagata gatttagcac aaaccgaaga attagaaaag
    22561 ttaattattt ataatagaac agatgctgaa attcagagat tatcaaattt tgatattatt
    22621 atatatgatt caaatgatta tgaagttttt acacaacata ttgacagttt agaaagcaat
    22681 aatctatcca tagacttaaa aggactgaag ggaaaaaagg ttagaatttc tttgagaagc
    22741 gcaggaattc ctttaagttt agcagaggta gaggtttata cttataagta attttaaaaa
    22801 ttatcaccca ggctaccgta aatataatgg agatggtagt atgaaagaaa cagaaaaata
    22861 agaggaaaat agtatgattc aacatccacg tattgggatt cgtccgacta ttgatggtcg
    22921 tcgtcaaggt gtacgcgaat cacttgaagt gcaaacaatg aacatggcta aaagtgtggc
    22981 agatttgatt tcaagcacat tgaaatatcc agatggggaa cctgtggaat gcgtgatttc
    23041 tccatctact attggccgtg taccagaggc tgcagcttcc catgagttgt ttaaaaaatc
    23101 aaatgtttgc gcaacaatta cagttacacc atgctggtgt tatggtagtg aaactatgga
    23161 tatgtctcca gatattcctc atgctatttg gggatttaat gggacagaac gcccaggagc
    23221 tgtctatctt gcagctgtac tagcttcaca tgctcaaaaa gggattccag cctttgggat
    23281 ttatggaaga gatgttcagg aagctagtga cacagatatt ccagaagatg tcaaagaaaa
    23341 acttttacgc tatgcgcgtg cagctcttgc aactggcttg atgagagaca ctgcttacct
    23401 atcaatgggt agtgtttcga tggggattgg tggttctatt gtaaatccgg atttcttcca
    23461 agaataccta ggaatgcgaa atgaatcggt agatatgacg gagttcacgc gccgtatgga
    23521 ccgtagtatt tacgaccctg aagagttcga acgtgcgctc aaatgggtga aagaaaacgt
    23581 aaaagaagga ttcgaccata accgtgaaga ccttgtttta agccgtgaag aaaaagatag
    23641 acaatgggaa tttgttatta agatgttcat gattggacgt gacttaatgg ttggtaaccc
    23701 aagacttgct gaacttggtt ttgaggaaga agcagttggt caccatgctt tagtagctgg
    23761 tttccaaggt caacgtcagt ggacagacca ttttccaaat ggagatttta tggaaacttt
    23821 cctcaatact cagtttgact ggaatggtat tcgaaaacca tttgtatttg cgacagagaa
    23881 tgattcacta aatggtgtgt ctatgctctt taattatcta ttaacaaata ctccacaaat
    23941 ctttgctgat gtgcgtactt attggagccc agaggctgtt aaacgtgtaa cgggacatac
    24001 tttagagggt cgtgctgcag ctggcttctt acatctaatc aactctggtt cttgtacatt
    24061 ggatggtaca ggtcaagcta ctcgagatgg caaacctgtt atgaaaccat tctgggagtt
    24121 ggaagaaagt gaagtgcagg ctatgcttga aaatacagac ttcccaccag caaaccgcga
    24181 atacttccgt ggaggaggat tctcaactcg tttcttgacg aagggggata tgccagtaac
    24241 aatggtacgt ctcaatcttc taaaaggggt tggtccagtg ctacaaattg cagaaggtta
    24301 tacacttgaa cttcctgaag atgttcacca tactttagat aatcgtacag atccaggatg
    24361 gccaactact tggtttgctc cacgtttgac aggaaaaggt gctttcaagt ctgtctatga
    24421 cgtcatgaat aattggggag ctaatcacgg agccataaca tatggacaca ttggagcaga
    24481 cttgattacc ttggcttcta tgttgagaat tcctgtcaat atgcataatg tacctgagga
    24541 agatatcttt agacctaaaa attggtcctt atttggaaca gaagatctag aatcagcaga
    24601 ctattgtgca tgtcagttgt tgggaccact acataaataa aacttgttta tataggaggt
    24661 gaacttacgt ccctcctatc cttttaaaaa gatttgttaa acaattcaca aataattaaa
    24721 aacgaataca aaaagtaata taatgatgtt aaatagatag cgcggaggcg caggaggaaa
    24781 attatatggc tacattttat gttccggcag tcaaccttat tggaaaaggt gttgtaaatg
    24841 aagtgggtcc ttatatcaag gaacttggct ataaaaaggc acttttggtt acagataagt
    24901 acatcgaagg cagtgatatt ttacctaaga ctttaaaacc actggataca gaaggaatcg
    24961 aatatgtcat ctttagcgat gtagagccaa accctacttg taaaaatgtc acagatgggg
    25021 tagctgcttt gcaagaacat ggctgtgact ttatcatcag tcttggcggg ggttctccac
    25081 aggatgcagc tagttgtatt tctatcatgg ctacaaatgg tggaaaacca caggattatg
    25141 aagggcttca taagtctgct aaaaaaggct tgccagttgt ggctatcaat acaacggcag
    25201 gaacttctgc agaaatcact attaactatg tgattactga tgaagaacgc aaggttaaga
    25261 tggtaatggt tgacaagaat agccttgctc ttatctctgt taatgacccg gaactcatgc
    25321 tttccaaacc taaaggcctg actgctgcta ctggtatgga tgctctgact cacgctgttg
    25381 aagctttggt aacacctggt gcttatgatg taaccaagaa actgtctatt ggtgctattg
    25441 agcttatcaa ggaatatctt cctcgtgctg tagaaaatgg acatgatatt gaagcgcgtg
    25501 aaggtatggt caatgccatc ttccttggtg gtatgagctt taataatgct ggtcttggtt
    25561 atgttcactc aatggctcac caactcggtg cagtatataa tttgccacat ggcgtgtgct
    25621 gtgccatgtt gctaccagtt atagaacgtg aaaatgctaa acgtgtacca gaagctttcc
    25681 gcaatgttgc caaagccttg ggacttcatg tagaaggtaa atcagatcaa gaatgtgccg
    25741 attatgcgat tgctgagatt gagaagcttt ctgagacagt aggtattcct aagaaactga
    25801 ctgaacttgg tattgaagaa aaagatttcg actttgaata cctttctaag aatgccttga
    25861 ttgatgcctg cgcaccagga aatccattta tgccaacctt agaagaaacg attgcctttt
    25921 ataaagagtt attttagcaa gagattggac gacaatagga caattcacct ctaattattg
    25981 acatttcagg aaaaatcgca gtaaaaacgg cacagccttc tttaaatgtg ctataatact
    26041 agaaaaatac ttgtggaggt tccattatgg caatattttt catgattttt ctgattgttt
    26101 gtgtgctcct attggtgata gtcacactga gtacagttta tgtggttcgt cagcagtcgg
    26161 tggcgattat tgaacgcttt gggaaatacc aaaaggttgc taatagcggt attcatattc
    26221 gcttgccttt tgggattgac tcgattgcag cacggattca gttgcgcttg ttgcaaagtg
    26281 atattgtggt tgagactaag accaaggaca atgtgttcgt tatgatgaat gtagcgactc
    26341 agtaccgtgt caacgagcag agcgtgacag atgcttacta taaactcata cgtccagaat
    26401 ctcagattaa atcttatatc gaagatgctc ttcgctcttc tgttccaaaa ttaaccttgg
    26461 atgaattgtt tgagaaaaaa gatgagattg cccttgaggt tcaacaccaa gtagcagaag
    26521 aaatgaccac ttacggctac attatcgtga aaaccttgat taccaaggtc gaaccagatg
    26581 cagaagttaa gcaatccatg aatgaaatca atgcggcgca acgtaagcgg gtcgcagcac
    26641 aagaattggc ggaagctgac aagattaaaa ttgtcactgc agctgaagca gaagcagaaa
    26701 aagaccgcct tcatggtgtg gggattgccc aacaacgtaa ggcgattgtg gatggattgg
    26761 cagagtctat caccgaactc aaggaagcca atgttggcat gacagaagaa caaatcatgt
    26821 ctatcctctt gaccaaccag tatttggata ccttgaatac ctttgcctct aaaggaaatc
    26881 aaaccatctt tttaccaaat actccaaatg gtgtggatga tatccgaaca caaatcttgt
    26941 cagcccttcg cgctgagaag aaataataga ctaatactct tcgaaaatct cttcaaacca
    27001 cgtcagcgtc gccttgccgt atagatgtta ctgacttcgt cagttctatc tgcaacctca
    27061 aaacagtgtt ttgagctgac ttcgtcagtc ttatctacta cctcaaaacg gtgttttgag
    27121 caacctgtgg ctagtttcct agtttgctct ttgattttca ttgagtataa agagcttggc
    27181 aacaggctct ttttgtattg cgtttattaa gaaaaacaaa aaacatcgat atacatttaa
    27241 ctaaaaatta ttgtatgtca tctcccttaa ttaggaatga taagggaata actagaaaga
    27301 tttgtgaata caaactattt ctgatataca aaatatacag taataatgaa tgatgggaga
    27361 tgggatgaaa gaatttcaat ttgagagaaa gcagcgtttt tctttgagga aatatgcaat
    27421 aggagcttgt tcggtcttgc taggaacgag tttatttttt gctggtatgg gtgctcagcc
    27481 tgtacaggat acagaaacga gttcagcact aatttcaagt cattatttgg atgagcagga
    27541 tttatctgaa aagctgaaat ctgagttgca atggtttgaa ttagaaaaca agcttttgaa
    27601 cttatgggag cattaggtta ctatgaagga tttgttcctt atgtttcaaa tcaatacaaa
    27661 aaccaagctg aagaagaata caaaccgcta tctgataaat atattttcga aaaaatctta
    27721 ggaaaaacat atgcagcctt caaaaaagat caaattaatg agcgtgtcga gaaattaggt
    27781 aagttaaaac ctattacaat aaattacaac ggaaaatcag aagtaattga tagtaaagaa
    27841 aaattacaag agcttatgaa taaagccgtt aaagacgaag tggctcaaat atagtaaaat
    27901 gaaataagaa caggacaaat cgatcaggac agtcaaatcg atttctaaaa atgttttaga
    27961 agtagaggtg tactattcta gtttcaatat actataaaat caggcaatac cacggctaaa
    28021 aagtttgagt ttatcgaaac accagtgcaa aaactgaaaa aagcgattta taaagctcat
    28081 ctcaaagatt cagat
//
LOCUS       DBERXF010000028        27863 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.28, whole genome shotgun sequence.
ACCESSION   DBERXF010000028 DBERXF010000000
VERSION     DBERXF010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.28"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            29..834
                     /locus_tag="ACL8JK_001352"
                     /pseudo
     CDS             29..834
                     /locus_tag="ACL8JK_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            856..1595
                     /locus_tag="ACL8JK_001353"
                     /pseudo
     CDS             856..1595
                     /locus_tag="ACL8JK_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            1608..2774
                     /locus_tag="ACL8JK_001354"
     CDS             1608..2774
                     /locus_tag="ACL8JK_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGS1786226.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYV
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            3282..4775
                     /locus_tag="ACL8JK_001355"
     CDS             3282..4775
                     /locus_tag="ACL8JK_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGS1786227.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            4788..5705
                     /locus_tag="ACL8JK_001356"
     CDS             4788..5705
                     /locus_tag="ACL8JK_001356"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1786228.1"
                     /translation="MKKVKLGEILSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNLNWQSKNLWKNLKL"
     gene            5797..6033
                     /locus_tag="ACL8JK_001357"
     CDS             5797..6033
                     /locus_tag="ACL8JK_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGS1786229.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            6030..6443
                     /locus_tag="ACL8JK_001358"
     CDS             6030..6443
                     /locus_tag="ACL8JK_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGS1786230.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            6561..7526
                     /gene="xerA"
                     /locus_tag="ACL8JK_001359"
     CDS             6561..7526
                     /gene="xerA"
                     /locus_tag="ACL8JK_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008907 - integrase activity [Evidence
                     IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase/integron
                     integrase"
                     /protein_id="HGS1786231.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            7560..8666
                     /locus_tag="ACL8JK_001360"
     CDS             7560..8666
                     /locus_tag="ACL8JK_001360"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1786232.1"
                     /translation="MKKVKLGEVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSTEIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWRGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIMVSYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNT
                     KNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLR
                     INSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLAL
                     QNEFADFVALVDKSQFACEIAIKVWRNSLKFSII"
     gene            8696..12046
                     /locus_tag="ACL8JK_001361"
     CDS             8696..12046
                     /locus_tag="ACL8JK_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGS1786233.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDQEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDNSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(12551..13021)
                     /locus_tag="ACL8JK_001362"
     CDS             complement(12551..13021)
                     /locus_tag="ACL8JK_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS1786234.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(13038..15311)
                     /locus_tag="ACL8JK_001363"
     CDS             complement(13038..15311)
                     /locus_tag="ACL8JK_001363"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HGS1786235.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEVELEVKLPHKIELEEPQLNLVQPQGQAELVAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYSKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            15657..18758
                     /locus_tag="ACL8JK_001364"
     CDS             15657..18758
                     /locus_tag="ACL8JK_001364"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGS1786236.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGVK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQLRDGRLQMIAQEIREAVAERFWIQ
                     VKNHDSDQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            18840..19847
                     /gene="pfkA"
                     /locus_tag="ACL8JK_001365"
     CDS             18840..19847
                     /gene="pfkA"
                     /locus_tag="ACL8JK_001365"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGS1786237.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            19904..21409
                     /gene="pyk"
                     /locus_tag="ACL8JK_001366"
     CDS             19904..21409
                     /gene="pyk"
                     /locus_tag="ACL8JK_001366"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGS1786238.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAIEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(21628..21981)
                     /locus_tag="ACL8JK_001367"
     CDS             complement(21628..21981)
                     /locus_tag="ACL8JK_001367"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HGS1786239.1"
                     /translation="MTLQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHK
                     NAKTVNNIYTHVSKRMEQATLEVLNTISLNRKYIRSNLDKYITIAKTFVEIHLNFLIN
                     LCISYFILNENQRAN"
     gene            complement(22151..22366)
                     /locus_tag="ACL8JK_001368"
     CDS             complement(22151..22366)
                     /locus_tag="ACL8JK_001368"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HGS1786240.1"
                     /translation="MEPKIRNSDYLFIKNTPQIDYNTIGIFQVDGTNYVKKLRQGYLK
                     KTQSRILRHPPRRKQPYSYHRESCQAI"
     gene            23214..24086
                     /locus_tag="ACL8JK_001369"
     CDS             23214..24086
                     /locus_tag="ACL8JK_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HGS1786241.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEGPYQAIKFASKEDCYKYLDTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(24235..24575)
                     /locus_tag="ACL8JK_001370"
                     /pseudo
     CDS             complement(24235..24575)
                     /locus_tag="ACL8JK_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            24718..25029
                     /locus_tag="ACL8JK_001371"
     CDS             24718..25029
                     /locus_tag="ACL8JK_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786242.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            25033..25749
                     /locus_tag="ACL8JK_001372"
     CDS             25033..25749
                     /locus_tag="ACL8JK_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS1786243.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFNTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(25879..26694)
                     /locus_tag="ACL8JK_001373"
     CDS             complement(25879..26694)
                     /locus_tag="ACL8JK_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGS1786244.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(26691..27596)
                     /locus_tag="ACL8JK_001374"
     CDS             complement(26691..27596)
                     /locus_tag="ACL8JK_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGS1786245.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(27597..27728)
                     /locus_tag="ACL8JK_001375"
     CDS             complement(27597..27728)
                     /locus_tag="ACL8JK_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGS1786246.1"
                     /translation="MAVKFTKRDDLDKMFEEFAKLPDLKQVTFPDDKEKKVKAEKKN"
BASE COUNT         8893 a         4710 c         5869 g         8391 t
ORIGIN      
        1 aattttgaat atagagagtt ttctgacaat gaatcaatcc tacttttatc taaaaatgaa
       61 agaacacaaa ctcaaggttc cttatacagg taaggagcgc cgtgtacgta ttcttcttcc
      121 taaagattat gagaaagata cagaccgttc ttatcctgtt gtatactttc atgacgggca
      181 aaatgttttt aatagcaaag agtctttcat tggacattca tggaagatta tcccagctat
      241 caaacgaaat ccggatatca gtcgcatgat tgtcgttgct attgacaatg atggtatggg
      301 gcggatgaat gagtatgcgg cttggaagtt ccaagaatct cctatcccag ggcagcagtt
      361 tggtggtaag ggtgtggagt atgctgagtt tgtcatggag gtggtcaagc cttttatcga
      421 tgagacctat cgtacaaaag cagactgcca gcatacggct atgattggtt cctcactagg
      481 aggcaatatt acccagttta tcggtttgga ataccaagac caaattggtt gcttgggcgt
      541 tttttcatct gcaaactggc tccaccaaga agcctttaac cgctatatcg agtgccagaa
      601 actatcgcct gaccagcgca tcttcatcta tgtaggaaca gaagaagcag atgatacaga
      661 caagaccttg atggatggca atatcaaaca agcctatatc gactcgtcgc tttgctatta
      721 ccatgatttg atagcagggg gagtacatct ggataatctt gtgccatcca tagtgaaatc
      781 ccttggtcag aaaatctacc agattgtctg agattttttg cagaaaaatg gtaagttaag
      841 aaaggaaaaa acgaaatgca tattgaacat cttagccact ggagtggtca tcctaaccgt
      901 gaaatgtacc ttaaccgtta tggacatggt gggattccag ttgtggtctt tgcttcatca
      961 ggtggtagtc acaacgaata ctatgatttt ggcatgattg atgcctgtgc ttcctttatc
     1021 gaggaaggcc gtgtccagtt ctttacccta tctagtgtgg atagtgagag ctggttggct
     1081 acttggaaaa atgctcatga ccaagcggaa atgcaccgtg cctacgaacg ttatgtgatt
     1141 gaggaggcca ttcttttatc aagcacaaga caggttggtt tgatggcatg atgacgacag
     1201 gttgctctat gggagcctat catgcactta atttcttcct ccagcatcca gatgtcttta
     1261 ccaaagtgat tgctctcagt ggtgtttacg acgcacgttt ctttgtcggt gattactaca
     1321 acgatgatgc tatttaccaa aactcgccag tagattatat ttggaaccaa aacgacggct
     1381 ggtttattga ccgttaccgt caggcagaga ttgtgctgtg tacggggctt ggagcctggg
     1441 aacaagatgg tttgccatcc ttttacaagc tcaaagaagc ctttgacaag aaacaaattc
     1501 cagcctggtt tgctgaatgg ggacatgatg tcgcccatga ctgggaatgg tggcgtaaac
     1561 aaatgcctta tttcctcggt aatctctatt tataaaagga gttacctatg aattaccttg
     1621 ttatttctcc ctactatcca caaaactttc aacagtttac catcgaacta gctaataaag
     1681 gcatcacagt cttgggaatt ggtcaagagt cttacgagca attggatgag cccttgcgca
     1741 atagcttgac cgagtatttt cgtgttgata atcttgagaa catagatgaa gtcaaacgtg
     1801 cagttgcttt tctcttttat aaacatggtc caattggccg catcgagtct cacaatgaat
     1861 actggcttga gctagacgca acactcagag aacaattcaa tgtttttggt gccaaaccag
     1921 aggatctcaa aaagacgaaa tataagtctg aaatgaagaa acttttcaaa aaagcaggtg
     1981 ttcctgtggt acctggagct gttatcaaga cggaagcaga tgttgatcaa gcagtgaaag
     2041 aaatcggtct tccaatgatt gccaaacctg ataatggagt gggagcagcc gcaaccttta
     2101 aacttgagac agaagacgat atcaatcact tcaagcaaga atgggaccat tcaacccttt
     2161 atttctttga aaaatttgtc acttccagcg aaatctgtac ctttgacggg ctcgtggaca
     2221 aggatggaaa gattgtcttc tcaacaacct ttgactacgt ctatacaccg cttgacctca
     2281 tgatttataa gatggacaat tcttattatg tgctcaagga tatggatcct aaactgcgca
     2341 agtatgggga agcaattgtc aaagaatttg gtatgaaaga acggtttttc catattgagt
     2401 tcttccgtga gggggacgat tatattacca tcgagtacaa taaccgccct gcaggtggtt
     2461 ttaccattga tgtttataac tttgctcatt ccttggacct ttatcgtggc tatgcagcta
     2521 ttgtcgcagg agaggagttc ccggcgtcag actttgaaac tcagtattgt ttggctactt
     2581 ctcgccgtgc aaatgctcac tatgtttatt cagaagagga tttgcttgcc aaatatagcc
     2641 agcagttcaa ggttaaaaaa gtcatgccag ctgccttcgc ggaacttcaa ggagattacc
     2701 tgtatatgct gaccactccg agtcgacaag aaatggagca gatgattgca gatttcggac
     2761 aacgtcaaga ataagaacta tcggattaag gaaattcact cccttaatcc ttttgttttg
     2821 tctggtaaaa aataagagca tcctaacaag gtagctatca taaaacttgt tcgataacta
     2881 tttgaagcag gattaggtgg ctagaaattg aattttaaca tttcaattga gtcatagtat
     2941 tgtgttttcg tatccttaaa tcagctaaaa ggatccatga cgacacctat acgatatagt
     3001 tttcaggata ccaaacaagt ctattaatac tcaatgaaaa tcaaagagca aactaggaag
     3061 ctagccgcag gttgctcaaa acactgtttt gaggttgtgg atagaactga cagagtcagt
     3121 atcatatacc tacggcaagg tgaagctgac gtggtttgaa gagattttcg aagagtataa
     3181 aatattcagg tgacgcatag atatagttaa ttgaagcttt gtttgaaatc tgataaaata
     3241 atgatattac taagttctaa aaactaaaga aaagggaaga tatgattaca ggcgaattaa
     3301 aaaataaaat cgatcagctg tgggaaattc tttggacaga aggaaacgca aatcctttaa
     3361 caaatattga acagttgact tatctcttat ttatgaaaga tttggatagt gtcgagcttg
     3421 gacgtgaaag tgatgctgaa tttctaggga ttccttatga gggagttttt ccaaaagata
     3481 aacctgaata ccgttggtca acttttaaaa atataggaga tgctcaggaa gtttatcgtt
     3541 taatgactca ggagattttt ccgtttatta aaaatctcaa gggggataca gatgatacag
     3601 ccttttcacg atatatgcga gaagctattt ttcaaataaa taaacctgct acgcttcaaa
     3661 aggcaatttc tatcttagat gtttttccaa ctaggggatt agatgtagat tttgataatg
     3721 acaaacaaag tattactgat atcggagata tctatgaata tctgttatca aaattgtcga
     3781 ccgcaggtaa aaatggacag ttccgtacac ctcgtcacat catcgatatg atggttgagt
     3841 tgatgcaacc gactatcaaa gatatcatct cagatcccgc tatgggttct gctggcttct
     3901 tagtatctgc tagccgttac ttaaagcgta agaaagatga atgggaaacc aatacagata
     3961 atatcaatca ttttcataat cagatgtttc atggaaatga tacggatacg actatgttga
     4021 gacttggggc gatgaacatg atgctacatg gagtagaaaa tccacaaatc agttaccttg
     4081 actcgctgtc tcaagataat gaagaagccg ataaatatac tttggtttta gcaaatcctc
     4141 cttttaaggg ctcacttgac tacaattcaa cctctaatga ccttcttgca accgtaaaaa
     4201 ccaaaaaaac agaattactc tttctttctc ttttcttgcg aactttaaaa ccaggtggac
     4261 gagcagcagt tatcgtacct gatggtgtcc tttttggttc gtctaaagct cataaaggaa
     4321 ttcgtcagga aattgtagag aatcataagc ttgatgctgt aatctcaatg cctagtggtg
     4381 tgttcaagcc ttatgctgga gtttcaactg ctattctcat ctttacaaaa actggtaatg
     4441 gtggtactga caaagtctgg ttttacgata tgaaagcgga tggtttaagt ttggatgata
     4501 agcgacaacc gattagcgac aatgatattc cagatattat cgaacgcttt catcatcttg
     4561 aaaaagaagc agaacgtcag agaacggatc aatctttctt tgttccagtt gctgagataa
     4621 aggaaaatga ttatgatttg tctatcaata aatataaaga gattgagtat gaaaaagttg
     4681 agtatgaacc aacagaggtc atcttaaaga aaatcaatga tttagaaaaa gaaattcaag
     4741 ctggcttggc tgaattagaa aaattactca agtagggagg tggctgtatg aaaaaagtga
     4801 agttggggga aatcttatct ctaaaaaaag gaaagaaagc cactgtactt gctgaacaaa
     4861 caactctaag ccaacgttat attcaaatag atgatttaag aaataataat aatttaaaat
     4921 tcactgaaag tttaaatatg actgaagcac tcccagatga tattctaata gcatgggatg
     4981 gtgctaatgc aggaacagtt ggttatggat tatcgggagc tgttggtagt acaattacgg
     5041 tcttaaaaaa gaatgagcga tacaaagaaa aaattatatc agattacttg ggagtctttt
     5101 tggaaagtaa atcgcagtat ttacgagatc attcaacagg tgcaacaatt cctcatttaa
     5161 acaagaatat attacttgat ttacaattag aattgctagg tatcgaagaa caagagaaca
     5221 ttatctgtat tcttaatacg attaaaaggc ttattactaa aagaaaattg cagttagatg
     5281 aactaaactt gctcgtcaaa tcccgattta acgagatgtt tggggaaaat aaaatatttg
     5341 aaagcattga taacttattt gatattatag atggtgatag gggcaaaaat tatcctaaat
     5401 cagatgagtt gtttagtgag gagtactgtt tatttttaaa tacaaagaat gttactaaaa
     5461 acggattttc attcgataca aagcaattta tcactaaaac aaaggataaa ttacttcgaa
     5521 aaggcaaact tgagcgttat gatatagtct tgacaacaag aggtactgtt ggaaatgtag
     5581 cgtactacga tgaattaata aaatataaac atttacgtat aaattcaggt atggtaatat
     5641 tacgtcccaa gacaccaaat ctaaattggc aatccaaaaa tctctggaag aacttgaaac
     5701 tttgaagaaa tctctgatgc aggagtattt tggctgatat tctgccattg taattacggt
     5761 aatgatttgt tataatactt caaaggagga aatcagatgg tagtaaaaac aagaaaacaa
     5821 ggaaattcaa tcaccattac gattccaagt gaatttaata ttccaagtgg tgttaaatac
     5881 gaagcgaaat tgttaccaag tggtgagatt atctttactc ctgaagaatt ggggcagcag
     5941 gtttcttatg tatctgatga tgcctttgac ttaaatttag ataaaatatt tgacgaatac
     6001 gacgatgttt tcaaagcttt ggtggaaaaa tgacaatcta tctgacagaa aagcaaattg
     6061 aaaaaataaa tgctttagca attcaacggt attctccaaa tgagaaaatt caaacagtta
     6121 gttcttctgc cttaaatatg attgtgaact taccagaaca atttgtcttt gggaagtctc
     6181 tttatccaac aatttttgat aaagcaacga tactatttgt ccaattgata aagaagcatg
     6241 tttttgctaa tgctaataaa agaactgctt tcttcgtttt ggtcaaattt ttacaattaa
     6301 acggctatcg tttttctgta acggtagaag aagcagtaaa aatgtgtgta accatcgcag
     6361 tagaagcttt aactgatgaa aaaatgacaa gctactccaa atgggtttct gaacattctg
     6421 ttagagaaaa ggtcaaaaag taacctagta tgctggattt gaatgagcac aagaaaataa
     6481 atgaacagac aatattagaa ttctgtaatg cagaaactga tattgtctct ttttattgat
     6541 gaataagaaa gtgagaaatt atggaatcaa aagttacaat tatcatgcaa gaaatgttac
     6601 ctcttttaaa taatgaacaa ttactagcgt tgagagagag tttagaacat catctagtag
     6661 acggaaaaaa gcagcagaag tattcgaata ataacctgtt gcaactattt attaccgcca
     6721 agcaggtaga gggctgtagc tcaaaaacaa ttcgttatta ccagaggacg attgaaaact
     6781 tgtttaatgc tattaaagag tctgtgacac aactcacaac agatgattta aggagttatt
     6841 tagcaaatta ccagtctgaa aaggattgta gtaaggcaaa tttagacaat attaggcgta
     6901 tattgtcttc tttttttgct tggcttgagc aagaggaata tatcattaaa aatcccattc
     6961 gacggataaa gaaaattaag actgagcaaa atgtgaagga aacttatact gatgaacatt
     7021 tggaaattat gcgtgataac tgtgaaaatt tgagagattt ggcaataata gacctactag
     7081 catcgacagg tatgcgtgta ggggagcttg tacagttgaa tcgttcagat attgattttg
     7141 aaaacagaga gtgtgttgtc tttggtaaag gaaagaagga gagaccagta tattttgacg
     7201 ctcggacgaa aattcattta agaaattatc ttaacgacag aaaagatagt caccctgctc
     7261 tttttgtaac gctagttgga aaagcccaga gacttggaat tgctggtgta gagattcgct
     7321 taagaaagtt aggagacaaa ctcggcatac aaaaggttca cccacataag ttcagaagaa
     7381 ctttagcgac taaggcaatt gataaaggta tgcctatcga acaagtccaa aaactgctag
     7441 gtcatagcaa gattgacaca accctggcct atgccatggt caatcaaaat aatgtcaagc
     7501 attcacacca aaaattcatc tcttaaaagc aaatcccgat attccgagga ggtggttgca
     7561 tgaagaaagt gaaattaggt gaagtggcta cttttatcaa tggctatgct tttaaacctc
     7621 aagattggtc atctgaaggg aaagagatta tcagaataca gaatctgact aaaacttcaa
     7681 cagagataaa ttattattcg ggtacgattg ataaaaaata cattgttgaa gctggtgata
     7741 ttcttatttc gtggtcgggt acattagggg tttttcagtg gcgtggaaga tccgcagtgt
     7801 taaatcagca catttttaaa gtggtttttg ataagataga tatagataaa tcgtatttta
     7861 aatatgttgt tgaaaaaggt ttacaagatg ctgtaaaaca tactcatggt tccacaatga
     7921 aacatttaac taaaaaatat tttgataata ttatggtttc atatacaaat ttgggagagc
     7981 aacaaagaat tgcaagtgag ctggatttgt taagcaagct gattttaagg agacaagaac
     8041 aacttgaaga gcttaatcta cttgtaaaat cccgatttaa cgagatgttt ggggaaaata
     8101 aaatatttga aagcattgat aacttatttg atattataga tggtgatagg ggcaaaaatt
     8161 atcctaaatc agatgagttg tttagtgagg agtactgttt atttttaaat acaaagaatg
     8221 ttactaaaaa cggattttca ttcgatacaa agcaatttat cactaaaaca aaggataaat
     8281 tacttcgaaa aggcaaactt gagcgttatg atatagtctt gacaacaaga ggtactgttg
     8341 gaaatgtagc gtactacgat gaattaataa aatataaaca tttacgtata aattcaggta
     8401 tggtaatatt acgtcccaag acaccaaatc taaatcagaa atttattatc catgttttaa
     8461 ggaataataa ttatagtcga gtgatatcag gaagtgctca gcctcagtta ccaattacaa
     8521 aattaaaaaa aatacttctc cctctccccc ctctagccct ccaaaatgag ttcgcagact
     8581 ttgtagccct ggtcgacaaa tcacaatttg cttgtgagat agctataaaa gtgtggagaa
     8641 atagcttgaa atttagtata atatagctaa actatttgtt taaagtgaga aaaaaatggg
     8701 aaattttagc tttcttttaa aaaatgacga atatgaatct ttttcaaaac cttgcattga
     8761 agctgagaat atgattgcta catcaactgt ggctactgcc tttatggcgc gtcgtgcttt
     8821 agagcaggct gtccattgga tatatagtca cgattcatat ttagaagctc cctatcgtgc
     8881 tactctatct tctttagtat gggatgatga ttttagggat atcgtagatt ctgaactcca
     8941 caagcagata gttctgttga ttcggtgggg aaaccatgct gctcatggtg gtgaaattaa
     9001 ggaacgagaa gcgattttag ctttgcatca tttgtatcag tttgttaatt ttatcgatta
     9061 ttgttacagc aatgagtttg tggagcgtta ttttgatgag aagtgcttac cactttcagc
     9121 aaacatcaaa taccgagaaa ctccacaatc tatgataaag ttacaagaca gtttaccaga
     9181 actgcctgat tttcatgaac agatggctgc tcagtccgta gaagttcaag agacttatac
     9241 tgaaaaacgt gagactgcag cgcaacggca agatgtgcct ttccatattg atcaattatc
     9301 tgaggcagag acaagaaagc tctttattga tatcgatctc cgtttagcag gatggatatt
     9361 tgaagaaaac tgtcgtgttg agatagccgt tgatggtctc aagcacggtt caggaattgg
     9421 ttactgtgac tatgtacttt atggtaaaaa tgggaaaatt ttagcgattg tggaggctaa
     9481 aaaagcctct gtcaatccag aagtagggga agtacaggtc aaagaatatg ctgaagcttt
     9541 ggagaaacat atcggctatc agccaatttg ctttattaca aatgggttga agcactatat
     9601 acttgatggt ccgaaccgcc gccagattgc aggcttttac tctcaagaag aattgcaatt
     9661 agtgatggat agacgtcatc ttcaaaaacc gcttgaggat atttctagta aaattaggga
     9721 cgatatttcc gggcgtcact accaaaaaca tgccattgca agcgtttgtg aagctttctc
     9781 taatcatcgt agacaggcac ttttggttat ggcaactggg gcggggaaaa ctcgtacagc
     9841 agtttctcta gttgatatct tatcacgtca taactgggta aaaaacgttc tcttcttagc
     9901 cgatagaact tccttggtta agcaagccta tgattcgttt agaaaattac tcccagatct
     9961 ttccgtttgt aacttcttag aagatcaaga aggagctcaa tcaagtcgta tggtcttttc
    10021 aacttatccg accatgattg gagcgattag tggtcaagaa gaagtaaatc aacgcccttt
    10081 tactgttggg cattttgacc ttatcataat tgacgaatct caccgttcta tttatcagaa
    10141 atacaagtcc atttttgatt attttgatgc aagaattgta ggcttaacag ctactccgcg
    10201 tcaagattta gataaaaaca cctatggatt ctttaatttg gagaatgggg ttccaacata
    10261 tgcatatgat ttggaagagg ctgttaaaga cggatattta gtagcctatc attctatcga
    10321 aaccaaactg aaactaccta cggatggtct acattatgat gatttgtccg aagaagaaaa
    10381 ggaacatttt gatagcaaat ttgaagacaa tagctgtgaa aaagatattg atgggagtgt
    10441 atttaattcc tttattttca ataaaagtac agtagaaatt gttttaaatg aactcatgac
    10501 aagaggaatt cagacagcct cgggtgatga aattggtaaa actattattt ttgctaaaaa
    10561 tcatgaccat gcggaatata tcagaggtat ttttaacaac cgctatcctg aaaaagggag
    10621 cgactatgct caggtgattg attatagtat taagcattat cagaccttga ttgatgattt
    10681 taaaattaag gagaagtatc ctcaaattgc gatttctgtc gatatgttag atacaggtat
    10741 tgatgtacca gaggttgtta atttagtctt cttcaagaaa gtacgctcta aaactaagtt
    10801 ttggcagatg attggtcgag gaacccgtct atgtaaagat ttatttggac ctgagcagga
    10861 taaggaaaac ttcttggtat ttgattatgg ggacaatttt gattattttc gtgcagatcc
    10921 aagagatgga gagggtcgtc acattgtttc gctgactcag cgtttattta atatcaaagt
    10981 ggacttgatt cgagaacttc agggactcca ataccaagaa gatcagtttg cgagagcata
    11041 ccgtcagcag cttgtctcgg aacttcaagg tcgtatagag agcttaaatg agttggactt
    11101 cagggttcgt atggttttag atacagttta tagctatagg aaattggaaa gttggcagaa
    11161 tctaactgct gttacaagtg aaaccattca aaaaaatctc tctccgcttt tatttgatga
    11221 agataaagaa gatgagatgg cgaggagatt tgatttgtgg ttgcttcata ttcagttggg
    11281 gcaactgaca gctaaatctt ccactgttca tatttcccaa gtgatgaaga cggctagagc
    11341 tctttctgct attggcaata tcccgcaggt ttttgagcag gctgaaatta tcaggaaagt
    11401 acaggagcct gaattttgga aagaagttaa cttgtctgat ttggaaaaaa ttcgtcttgc
    11461 tattcgagat ttattacagt ttttggataa aacagaccgt aaaccctact atgttaactt
    11521 tgaagatcgt atactctcca ctgttcacga gaccacagca tttttgcagg tcaacgatct
    11581 tcggtcttac aatgaaaaag ttgagcatta tttgaaaact catctggatg aggagtccat
    11641 ttctaagcta taccataata aaaagttgac atctgatgat atgcttgcac ttgaaaaatt
    11701 gctctgggaa aaattaggta gtaaagcaga ctaccaaagt cattatgaaa ataaggcaat
    11761 tccgagattg gttcgtgaga ttattggctt agatagagag tctgccaatc gtattttttc
    11821 taaatttttg tcggatgaga atcttaatgc caggcagatt tcatttgtaa aattgattgt
    11881 agactacatt gtagaaaatg gttttttaga gacgaaagtg ttaacgcaag agccgtttaa
    11941 atcttatggt tctgttcaac tactcttcca acaccaacta ccagtacttc gtaatattgt
    12001 tcaaatcatt gaacttatca ataatcgagc tggagaagcg gcttaaattc taaagtgatt
    12061 gccatgctga gactcattta aaattaaaaa gagtagaaat ttatgctata tatgagaagt
    12121 tttattagga agaatgtcat cgttttccta gaatacagta tcagttgtta agtggttgat
    12181 aaatttcaaa gtagatactt gtaccacgat gtttgttgat cgagttatta acaaaagagc
    12241 tactttgatt ttaaagaaat agaaaacaaa aagctgagca agaattcaat tgcaggagaa
    12301 aatgaaataa tactcaatga aaatcaaaga gcaaactagg aaactagctg caggctgctc
    12361 aaaacactgt tttgaggttg cagatggaag ctgacgcgga ttgaagagat tttcgaagag
    12421 tataaatctt cctaggataa agcaaaacgc atagtatcaa gggttttcaa cacttgatac
    12481 tatgcgtttt ctgatgttaa agactttcta ccagtttttt ttaagcataa ttgttagttg
    12541 tagtcattta ttattcttca aagaaaaatg gtggggcgaa ttttttcagt tcttcaaagc
    12601 acttttgagc agtatctgca tcttcacaga tgataagaca gacatcatta ccacaaaggg
    12661 tagcgatagc gtcagggaag ctcaaagtat caatgataga accaaaggat tgagccagtc
    12721 caggaagggt ttttagtagg acttggtgtt gaactgggcg catccagaca agggcgtctt
    12781 ccatgtagag ttcgagacgt ttttcccatt ttgagatgga accattgtta agaacataat
    12841 aagcgctatc ttcttcgcgg acttttgata ggttcatatt tttgatgtcg cgtgagaggg
    12901 ttgcctgggt tacttgaatg tcgttcttag caagaagggc ttgcaactca gcctgtgtat
    12961 gaatcttgtt ttttgtgata agagcgcgta taagttggtg gcggtgttct gatttattca
    13021 taataatgta actcctttta gcaaggtaag gtaagcatgg actgagcgag gtcgacagtc
    13081 aagtggtagt ctgtattgtc acggatggtg atttcaaagt cagtagtata gaggactaaa
    13141 cggagagtgt ctccttcttt tagcttgtaa atagttggct gcagttcaaa ttgaacatcc
    13201 atccattcat ctgcagtaat atcctctact aacagtaaat catttctatt ttgtaaatta
    13261 aggtaacctt ttgtcacgac tcgttgtgcc tctggtctaa atggcaattc acagagattt
    13321 tccaacatgt gatagcgacc gttgtcaatg gttctagcac ttaaaatagc tggataaggt
    13381 tgtaggtatt tcttttgccc aaattctagc agttgggcag ataagagccc cttgtttgta
    13441 ctggatttga tacgaagatt gagctgagcg cgaccgttta ggtggagatc tttagtcaca
    13501 ggaaggttaa tagtaatctg attagctttc ccttgataga gctctgtatt gaaggtttgg
    13561 tatgtcttac tatagcgctc aaaatcctta tctgggtact ggttttgaat agcttgctct
    13621 tcttgaccaa gtgagaaggt tttacagttt tcttgcccac cgaagttatc aagtgataac
    13681 caagtctgtg gagctgtatt gtcctgccag ataacagtag gaagttgaaa gtctgtttcc
    13741 tgtcctagta atttcttggt taataaggca tttatggact cacggaagtc aattgattgc
    13801 caattgttca tgtaaacatg ggcaccatta tggaaaaaga gatgcttgtg tatatgagta
    13861 ggaagagcat ggaacatctg gtaaacatga agtggtttga cattccaatc ctgagaacca
    13921 tgagtaaaga caacctctgc ctttacttta tgggcattga gcagataatt gcggtcatgc
    13981 caaaactgat tgtagtcccc agtttttcgg tctagctgag ctttcacttt ttctaagtca
    14041 gcttggtgag cttcattgcc acggatatag tcgccagcta agagattacg agaataggtt
    14101 aactcagcaa gggagtcaaa gtcctcacct ggataaccac ctgggctagt caccagaccg
    14161 ttttcacggt agtagttgta ccatgatgaa attcctgcct cggcaatgat aacttctaaa
    14221 ccatcgactc ctgtagtcgc aagaccattg gacatggtac ctagatagga aagtcccgtt
    14281 gtagcaactt ttccgtttga ccaatcagcc ttgacttgac gctggcgcgt gtgatcagta
    14341 aaggcacggc aacggccgtt aagccaatcg atgacatttt tataagcctc gatttgctgg
    14401 tagtctccat tagtcatgaa acctgtcgag tctttggtac caacacctga gacatagaga
    14461 ttggcaaagc ctctcggaag gaagtagtcg tttagtgtat agctagagtt gatgtgagtt
    14521 agcttttcct cagcctctgc tacaagctca gcttgacctt ggggttggac gagatttagt
    14581 tgaggttcct ctagctcaat cttgtgagga agcttaacct caagctcaac ctccatcttg
    14641 tagagagcct tgtcactagc cttgtcattg gttccctgat gataagggct ggctgtcatg
    14701 atggcaggga tttttccatc aaaacgaggg cgaataatgc taacctttac taggtctgat
    14761 agcccttttt ggtcagtatc gacacgagac tcaacgtaaa cgacttcacg aatgacatcc
    14821 tggttagaaa aagtagccaa actcttgccg ttaaagtagt ggtagtcatt atcctccgga
    14881 ataagaccat cactaacaag ttggtcgata agagtatttc cttttttggt gcgagtattg
    14941 agtaactgat agagattttc aatcaagtca ccatatataa tgggaaatcc agtttcttta
    15001 cgaaaaacgt cactatcttc gaagtcaacc aaataagaaa agcctaaaag ttgaaaagca
    15061 acagtataaa aaatatctgc tgtcagttca tcttctgatt gaaaaaatgt cagcaggtct
    15121 gtttttttat cagctgctag gatagaaagt gggtagttgg tgtcttgata agtgaaaaag
    15181 aaacgacgta aaaaggtttc aagtgagtct ttgtgattgg ctgtattttg taaatcaaag
    15241 ccacattttt ttagctcaga taagacattt tcttttggaa aattgatata actatattga
    15301 ttaaaacgca tagaacctcc atatagaatg acagttaagg ttattatatc aaaaaaaaag
    15361 cagaaaggga attgttaact tcaaaaggaa ataatccaat aaaaatgaat aaagtactaa
    15421 attcaatata gagaacagag taacaataag aataatagat agggtataaa agttctagga
    15481 gatttatatt atatgctttc tatttttata tacaatatag tataaatata aaaacgatga
    15541 caaaaataca aatgaataga aaataaatta gtaagctgat gaaatttttc tcaagagaag
    15601 ctatttatag gtgaaaatgg tataatatag tgagaaggat agaggagaag tgtaaattga
    15661 tcgcacaact agatacaaaa acagtctata gttttatgga aagcgtcatt tcgatcgaaa
    15721 agtatgtgag agcagctaaa gaatacggct acactcattt ggctatgatg gatattgaca
    15781 atctttatgg cgctttcgac tttctagaga ttacaaaaaa atacggcatt catcctttgc
    15841 tagggcttga aatgacagtg tttgtagatg atcaggaagt gaatttgcgc tttttagctc
    15901 tatctagtgt gggctatcag cagttgatga agctttcgac agccaagatg cagggggtga
    15961 aaacttggtc agtcctgtcc cagtacctgg aggatatcgc ggtcattgtg ccttattttg
    16021 atagagttga gtcgttagaa ctaggctgtg attactatat aggggtttat ccagaaacac
    16081 tagcaagcga atttcatcat cctatcttac ctctttatcg ggtcaacgct tttgaaagca
    16141 gggatagaga agttcttcaa gttttaacag cgattaaaga aaatctaccg ctcagagaag
    16201 ttcccttgcg ttcgagacaa gatgtcttta tatcagcaag ttctttagag aaactattcc
    16261 aagagtgttt tccgcaagct ttggacaatt tagaaaagct tatttcaggc atttcttacg
    16321 acttggatac tagtctgaaa ctgcctcgtt ttaatccagc tagaccagca gtagaggagt
    16381 tgagagagcg tgctgaactg gggcttgttc agaaggggtt gactagtaaa gaatatcaag
    16441 atagactaga ccaagaattg tctgttattc atgatatggg ctttgatgat tatttcttgg
    16501 ttgtttggga tttgttgcgt tttggacgat cgaatggcta ttatatggga atgggaaggg
    16561 gttctgcagt aggcagtttg gtttcttatg ccttagacat cacggggatt gacccagtag
    16621 agaaaaatct gatttttgaa cgctttctta atcgtgaacg ctataccatg cctgatattg
    16681 atattgatat cccagatatt tatcgtccag attttatcag atatgttggt aataaatatg
    16741 gtagtaaaca tgcggcacaa atcgttactt tttcaacctt tggagccaag caagctcttc
    16801 gagatgtttt gaaacgcttt ggtgtgccag agtatgaatt atctgcaatt actaagaaaa
    16861 tcagttttcg tgacaatctt aagtcggcct atgagggcaa tctccagttt cgtcagcaaa
    16921 tcaatagtaa gttagaatac caaaaagctt ttgagattgc ttgcaagata gagggctatc
    16981 caaggcaaac ctctgtccat gcggctggtg ttgtaattag tgaccaagat ttaaccaact
    17041 acattcctct aaagtatggt gatgaaattc cactgactca gtatgatgct catggagttg
    17101 aggctagcgg acttttgaag atggactttc tgggactacg aaatttgacc tttgtccaga
    17161 agatgcaaga gttgcttgct gaaacagaag gtattcatct gaaaattgaa gaaatcgatt
    17221 tagaagacaa agaaacgtta gctttatttg cctctggtaa tacaaaaggt atctttcaat
    17281 ttgagcaacc aggtgccatt cgtctgctta agcgtgtgca accagtctgt tttgaagatg
    17341 tcgtcgcgac tacttctcta aatcgaccgg gtgctagtga ctatatcaat aattttgtgg
    17401 caagaaagca tgggcaggaa gaagtgactg ttctggatcc agtactggag gatattttgg
    17461 ctccaaccta cggcataatg ctctatcagg agcaggttat gcaggttgcc cagcgatttg
    17521 ccggatttag tcttgggaaa gccgatattt tgcgtcgggc tatggggaaa aaggatgcct
    17581 ctgccatgca tgagatgagg gcttccttta ttcaaggttc attagaagct ggtcatactg
    17641 tggaaaaagc agagcaggtc tttgatgtta tggagaagtt tgcaggctat ggttttaaca
    17701 ggtcacacgc ctatgcctac tcagcattgg ccttccagtt ggcttatttt aaaacacatt
    17761 atccagccat attttatcag attatgttaa attcttccaa cagtgattac ttaatagatg
    17821 cacttgaagc aggttttgaa gtagcctctc tatccatcaa caccattccc tatcacgata
    17881 aaattgccaa caaggccatc tatctaggtt tgaaatccat taaaggagtc agtaatgatt
    17941 tagctctctg gattattgaa aatagacctt attctaacat tgaagatttt atagctaaat
    18001 tacctgagaa ttatctgaaa cttcctctgc tagaaccttt ggtaaaagtt ggtcttttcg
    18061 attcatttga aaaaaatcgt caaaaagtat ttaataactt agctaatcta tttgaatttg
    18121 tgaaagagtt gggaagtttg tttggagatg ctatttatag ttggcaggaa tcggaagatt
    18181 ggacggaaca agaaaaattt tatatggaac aagagctttt agggataggt gtcagcaaac
    18241 atccactaca agctattgca agtaaggcta tttacccgat taccccaatc ggaaatttgt
    18301 cagaaaatag ctatgctatt atcttggttg aagttcagaa aataaaagtg attcgtacca
    18361 aaaagggtga aaatatggcc ttcttacagg cagatgatag taagaaaaaa ttggatgtca
    18421 ctctcttttc agacttatat cgtcaggttg gacaggaaat aaaagaggga gccttctact
    18481 atgtaaaagg aaaaatacaa ttacgtgatg gccgtctgca aatgattgca caagaaataa
    18541 gagaagcagt tgctgaacgc ttttggattc aggttaaaaa tcatgactcg gatcaagaga
    18601 tgtcacgtat tttagaccag tataaaggcc caatcccagt catcatccgg tatgaagagg
    18661 aacagaaaac catcgtttct ccccatcatt ttgtagctaa atctgatgaa ttagaggcga
    18721 aattgaatgg aatagttatg aaaacgattt atcgctaaaa ttacggaaaa tagaagaatt
    18781 ttcaacgtaa atgtggtata atcagtaaga atgttaaaag aaaaaggagc ataaccaata
    18841 tgaaacgtat tgctgttttg actagtggtg gagacgcccc tggtatgaac gctgccatcc
    18901 gtgcagttgt tcgtcaagca atttcagaag gaatggaagt gtttggtatc tatgacggat
    18961 atgctggtat ggttgccggt gaaattcatc ccctagatgc agcttcagta ggggacatca
    19021 tttctcgtgg tggtactttc cttcactcag ctcgttaccc agagttcgct caacttgaag
    19081 ggcaacttaa agggattgag caattgaaaa aacacggaat tgaaggtgta gttgttatcg
    19141 gtggtgacgg atcttaccac ggcgctatgc gtttgactga acatggcttc ccagctattg
    19201 gtcttccagg tacaatcgat aacgatatcg ttggtactga ctttacaatc ggttttgaca
    19261 cagcggttac tactgccatg gacgctatcg ataagattcg tgatacatca tcaagtcacc
    19321 gtcgtacttt tgtaatcgaa gttatgggac gtaacgctgg tgatatcgct ctttgggctg
    19381 gtattgcaac tggtgctgat gaaatcatca tccctgaagc aggcttcaag atggaagata
    19441 tcgtagcaag catcaaagct ggttatgaat gtggtaaaaa acacaatatc atcgtcttag
    19501 ctgaaggtgt gatgtcagcg gctgaatttg gtcaaaaact taaagaagct ggagatacaa
    19561 gcgaccttcg tgtaacagaa cttggacata ttcaacgtgg tggttctcca actgcgcgtg
    19621 accgtgtttt ggcgtcacgt atgggtgcac atgctgttaa acttcttaaa gaaggtatcg
    19681 gtggtgttgc ggttggtatt cgtaacgaaa aaatggttga aaatccaatt cttggtactg
    19741 cagaagaagg ggcattgttt agccttactg cagaaggtaa gattgtggtt aacaacccgc
    19801 acaaagccga tattgagcta tctagcttga ataagagctt gtcataattt acaatttagt
    19861 taataagacc aaaaaggtca tatataaagg agtcacaaaa atcatgaaca aacgtgtaaa
    19921 gatcgttgca actttgggtc ctgcggtaga aatccgtggt ggtaaaaaat tcggtgagga
    19981 cggatactgg ggtgaaaaac ttgatgttga agcttcagct aaaaacattg ctaaattgat
    20041 tgaagctggt gctaacacat tccgattcaa cttctcacac ggcgaccacc aagaacaagg
    20101 tgagcgtatg gcaactgtta aacttgcgga aaaaattgca ggtaaaaaag ttggtttcct
    20161 tcttgataca aaaggacctg aaatccgtac agaattgttc gaaggtgaag ctaaagaata
    20221 ttcatacaaa actggtgaaa aaattcgtgt tgcaactaaa caaggaatca aatcaactcg
    20281 tgaagtgatt gcgttgaacg ttgctggtgc tcttgatatc tatgatgatg ttgaagttgg
    20341 tcgtcaagtt ttggttgacg atggtaaact tggtcttcgt gtggttgcta aagatgatgc
    20401 aactcgtgaa tttgaagttg aagttgaaaa cgatggtatc atcgctaaac aaaaaggtgt
    20461 gaacatccct aacactaaaa ttcctttccc agctcttgct gaacgcgata acgacgatat
    20521 ccgtttcggt cttgaacaag gtatcaactt catcgcaatt tcattcgtac gtactgcaaa
    20581 agatgtgaac gaagttcgtg caatctgtga agaaactgga aacggacatg ttcaattgtt
    20641 cgctaaaatc gaaaaccaac aaggtatcga taacttagac gaaatcatcg aagcagctga
    20701 tggtattatg attgctcgtg gtgatatggg tatcgaagta ccgttcgaaa tggttccagt
    20761 ttatcaaaaa atgattatca agaaagtcaa tgctgcaggt aaagttgtta tcactgcaac
    20821 aaacatgctt gaaacaatga ctgaaaaacc acgtgcaact cgttcagaag tatcagacgt
    20881 attcaacgct gttatcgacg gaactgacgc tacaatgctg tcaggcgagt ctgcaaacgg
    20941 taaataccca ctcgagtcag taactacaat ggctacaatc gacaagaacg ctcaagctct
    21001 tcttaatgaa tacggacgtc ttgattcaga ttcatttgag cgtaactcta agacagaagt
    21061 aatggcttct gctgttaaag atgctactaa ctcaatggat atcaaattgg ttgtaactct
    21121 tactaagaca ggtcatactg cacgtttgat ttctaaatac cgtccaaatg ctgacatctt
    21181 agcattgaca tttgacgaat tgacagaacg tggcttgatg ttgaactggg gtgttatccc
    21241 aatgttgaca gatgctccat cttcaactga cgatatgttc gaaatcgctg aacgtaaagc
    21301 gatagaagca ggtctcgttg agtcaggcga tgatatcgtt atcgttgctg gtgtgccagt
    21361 aggagaagct gttcgcacaa acacaatgcg tatccgcaca gtacgttaag aaaaatataa
    21421 aaacctatca tatccagctt tagagcttgt gtgataggct ttttgtatag agggtaagaa
    21481 ataggcaaaa ctttcataat ggattgatac tcttcgaaaa tcaaattcaa accacgtcag
    21541 cgtcgcctta ccgtatatat gttactgact tcgtcagttc tatctacaac ctcaaagcag
    21601 tgctttgagc aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtatgaa
    21661 ataagatatg cacaaattga ttaggaaatt caaatgaatt tctacaaatg ttttagcaat
    21721 cgtaatgtac ttgtctagat tcgatctgat atattttcga tttaatgata tggtatttaa
    21781 aacctccaaa gtagcttgct ccattctttt acttacgtga gtgtagatgt tatttactgt
    21841 tttagcgttt ttgtgttcca ctctaaccat tatagcattc ttctcagcta gtgtactaag
    21901 gagtgtgtgc ctgaaaatat gggaactaag gggctggttt atcggtttct ctagtttagt
    21961 atttgccttt tgcaaagtga tcttaaatgc ctttctctaa atttacatat cactattgtt
    22021 taacaaaatc taatctattt taggtcactt attctttttt tgaaatgtag aatgaacttt
    22081 ttcaaagttt ttcgaatctt ttaaaatctg tttgttttat atcgccattc tccccctttt
    22141 ttaattctcc ctatatagcc tgacaacttt cccgatggta cgaatatggt tgctttcgtc
    22201 taggtggatg tcggagtatt cgggattgag tttttttgag gtagccttgg cggagtttct
    22261 tgacatagtt agtgccgtct acttggaaga tgccgatggt attatagtca atctgtgggg
    22321 tattcttgat aaataggtag tcgctgtttc ttatctttgg ctccatggac ttgctgacga
    22381 cataagcgat tgggtcgtag tcgtctggga taatggaaac tccataacta aatcgtcgtc
    22441 ctgcatcaag cggctacctg cagagataaa ctacctaaca cgagagtaag tagtctgtct
    22501 gtagtcgtcc agtctgatga tttttacgat acttcgtttt tctgatcata cagttgcctc
    22561 tcggcatagg tcagaacttt accttgtctg ggtggtgccc gttggtcgta gatagattgg
    22621 atatcgctag gagaatcctt ttgaactgga ggaaagaggg catcaatcaa gctactgaat
    22681 actttaacta agtcaaatat agtatttttc ttagtagacc taaccctttt ttcataattt
    22741 ccaatggtgt ttttacttat accaatctta gtacccaatt cttattgagt ccaaccatta
    22801 ctagtctata ttgttttata gttgattgag tttggaatag tacgctgtag ctgctaaaac
    22861 atttctagga attaatttgc ctttcctaat agagttgttc atatcttatt tcaatctact
    22921 atatttttcg cctctaacaa tcgcaatctc ttctttatct acgaatgaaa tcgctttcta
    22981 tttttgtaag taaagcatca cacgaaatcc acgaaaatga aaacctttgt tgtgttttcg
    23041 taaaaaattt gttgacagag cacgaaacgc ctactataat taaatcaagc ttaaggaaat
    23101 aacaaaaaaa caaatcggag ggaaagacga tgaacatatt aaatgagaaa gtaatcaata
    23161 tctgtaaagc agtagttaaa gaaactttaa tccaagacat ttaggagaaa gaaatgaaga
    23221 aatcaagaaa attagccaca ttaggaatct gttcagcttt gtttttaggc ttggctgctt
    23281 gtcaacaaca acatgctact tctgagggga cgaatcaaag gcaaagcagt tcagcgaaag
    23341 ttccatggaa agcttcatac accaacctaa acaaccaggt aagtacagaa gaggtcaaat
    23401 ctctcttatc agctcacttg gatccaaata gtgttgatgc attttttaat ctcgttaatg
    23461 actataatac cattgtcggc tcaactggct tatcaggaga tttcacttcc tttactcaca
    23521 ccgaatacga tgttgagaaa atcagtcatc tctggaatca aaagaagggc gattttgttg
    23581 ggaccaactg ccgtatcaat agttattgtc ttttgaaaaa ttcagtcacc attccaaagc
    23641 ttgaaaagaa tgaccagttg cttttcctag ataatgatgc gattgataaa ggaaaggtct
    23701 ttgattcaca agataaggaa gagtttgata ttctattttc gagagttcca actgaggcaa
    23761 ctacagatgt caaggttcac gctgaaaaga tggaaacatt cttctcacaa tttcaattca
    23821 atgaaaaagc tcgaatgctg tctgtagtct tgcacgacaa tctggatggc gagtatctgt
    23881 ttgtaggcca cgttggggtc ttagtacctg ctgatgacgg tttcttattt gtagagaaat
    23941 tgactttcga agggccctac caagcgatta aatttgctag taaggaagat tgctacaagt
    24001 atttggacac caagtatgcg gattatacag gcgagggact ggctaagcct tttatcatgg
    24061 ataatgataa gtgggttaaa ctttaatagt gttatgatat gacagtaatc ttaggatttt
    24121 tatttctatt tttgatgagt tggtgggtta tttcaatcgt taatagccag aaaccacgca
    24181 aaaatgaaac atttattggc tatgtccaaa gatacgatat tgatgggaat ggctatcaat
    24241 cattaccgtg tcctcagaac tgagaggagt tcttgaaatc gtaaaaccac tttgaacaag
    24301 agttacttca acccattggc tccgacggat taagttgctt tcgtgaatac caaaatcagc
    24361 cgcaatttct tcataagtgc ggtattctcg cacatattga aagtggccat aagaaggtct
    24421 tctaggctta atttaggttt tcgtccacct tttgcgtgtt taagttgata agctgttttt
    24481 aatacagcta acatctcttc aaaagtcgtg cgctgaacac caacaagacg cttaaatcgt
    24541 gcatcagtta gttgtttact tgcttcataa ttcatagaac tattatacca tgttttgttt
    24601 cgcaggaaat ctaatgctaa aatcttatca gtgagaagat ttcttaaagt ttattctttg
    24661 tagtttcatc tgtattagta cataatttaa cttagagaaa ataggaggac taatcgaatg
    24721 gaattaaaag attttacaga aaaagaacag gaaatgatta agaaaaggct tacaatgtct
    24781 aatattagtg acaaagaaac tactgagaag attctggcgc tagtaccaca agacttgatt
    24841 aagcgaatcc cgttttttgt cagaaaacat gctacaacac gtacgattaa acgcatttca
    24901 attgaatacc ctgaactcta cgctgtagct caaacaagtg gtgagattcc agaaaaagaa
    24961 cgcgaagaat tgcgtcagat tatcacgact atctttgaac aaaagatgaa taagcatagt
    25021 attaagtaga gaatgaaaaa atattttatt agcggtttgg gaagcaatgc ctatcatagc
    25081 aaggattttt ttcaagaact agattcgcag gtctattttc taaatccata tgaaaagcat
    25141 cttcgagatg aaacagaatt gaaatcatgg tttaaaaatg agattgtaga ggaagaatct
    25201 atctgtctga taggccattc tcttggagga gatttagctc gttatttcgc atcggaattt
    25261 gaagaagtaa agaaactgat tcttttggat ggtggctatc tagatttaga taagatttta
    25321 cctttggata cagagttaga ggaaactaaa aattatatca aatctcaaat tgtttcggac
    25381 ttagctcttc ttatttctaa agagaagtcc gaagcaaagc attggtcaga aaatatggag
    25441 aaagctgtaa gacagtccta tcactggaat gttgagtata atagatatga gttggctata
    25501 aattatgaaa atatagaagc gatactccgc ctacggagaa aaatacaagc ttttaagaga
    25561 gaagtgggag ataccttgtt tattagtcct cgctatccta atggagctac atggagagag
    25621 gaagccctaa aagaattgcc agactatttt aatactattt ttttagaaaa ctttggccat
    25681 gagctttata ctcaagcacc taaagaaatc gctagtctaa tgaatgagtg gctcgcttat
    25741 tttctatgag ctacttgtat tgctggaaat ggtataagat gaaaatctac aagtcactaa
    25801 ttttcatata acaaaaaaac gaacaggctc tttttctgtt attcagaaga gaacttgttc
    25861 gtttttatct tgattttttt aaaaagctct atatacatag ggattttctg gtttatcgac
    25921 tttggtaaag ctgtcgattt ccaaggttgg aaggttttgt ttgagttctt tatggtagtg
    25981 attgaccagt tttcctttgg ctgtaatcca ggtgttgttt tcatactgcc gggtattgcc
    26041 cttggtcagc aatccataga caccagaatc tgcgatacag tggataatgc cgaatcggaa
    26101 cagaaattga ctattggcat gactggggtc gttatagaca aagcctgtaa actggattgt
    26161 cttgccctca aattcatctg gatagtcgta gatagcctcc atgacttcca tatagttttc
    26221 attagtgatc tgaatactat cttgggataa gtatttatcc gccgccgttc gcatttcctt
    26281 ttcataggct gattttgaaa aataagaact agtatctggt ttcaaatatt ggcttgtcgt
    26341 cccttcactt gtctgaatag ctagatccgt tccttccgat agggggaaat gataaccttt
    26401 agcagaaacg gtctgagaat ccaagctaac agttgggaaa gttaagccga tgacaagtgg
    26461 aatagccaga agagaaatac tcgtcatctt ggccaatcgg ctgttcagat gactgtgggt
    26521 tttgacttgc ttcatccaga tatacaattg aacaattgcc aagataaagg aaagcaccat
    26581 ggagatatag gccagatagg aatagtgcat gttgatgtac tggtttagtt tgcccgacag
    26641 atggaggtaa atagtcagtt caaaatagcc agctaaaact aaaaatcgaa tcataggatg
    26701 actccaatca agagagaata ggctaaaacg accagagtca caatcgtaat gaagtgacta
    26761 ataaatcgtg ctttcaagta atttttcatc atgagaatat ttttgatatc cagcattggg
    26821 ccaatgacga gaaaggccag aactggtgcc aaaccgaaac tcgagagtag agaagcacct
    26881 ataaaggcat ccgcctcact acagagcgaa agaagaaagg ctaaaagcat caagagcagg
    26941 atagcaaaaa gaggagtcgc actgatagag gtcagaatcc gagtcggaac gtagacctgt
    27001 attatagaag caaagaggca gccaaatacc aaataacgcc ccgtatcaaa aaattcatca
    27061 atggcctgca caaagacttg aaaaactttt tttgcagaac tcaagtaaga aaaatcatgc
    27121 tcatgacaag ccagacgatt ttctttctga atcggttctt gccagaaaaa tcctagaaaa
    27181 attcctagta ttacagccac aagaatggaa cccagagctc gtaatagtgc gacatggaag
    27241 gagttgccaa aggcagaata ggtcgcaaaa agaacaatgg gattgataac aggtgctgtc
    27301 acaagaaaag gaacggccgt gtaacttgga accttttttt ccagaaaacg attgatgatg
    27361 gggacgattc cacattcaca agaagggaaa agtataccga caaaggtccc aaaaaagatt
    27421 ctcccccaac gatttcgagg gagaaaatga taaaccttgt caggtgtgat ataaacttca
    27481 atcagccctg agacaatgct tcctatcaga acgaagggaa gggcttcaat gataatggag
    27541 agaaaaatgg ctccagtttg aagtacacta gatgggagtt gttgaaaagc agtcatctag
    27601 tttttctttt ctgctttgac ttttttctct ttgtcatcag ggaaagtaac ttgtttcaaa
    27661 tcagggagtt tagcaaactc ttcaaacatc ttgtccaagt cgtctcgttt tgtaaatttt
    27721 acagccatag gtgtacctcg attctaaatt ctacctctat tatactatta ttttgcggaa
    27781 aagggagttt tttaatttgt tttcgatagt tgatactctt cgaaaatctc ttcaaaccac
    27841 gtcagcttcg ccttaccgta gta
//
LOCUS       DBERXF010000029        27658 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.29, whole genome shotgun sequence.
ACCESSION   DBERXF010000029 DBERXF010000000
VERSION     DBERXF010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.29"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(103..690)
                     /locus_tag="ACL8JK_001376"
     CDS             complement(103..690)
                     /locus_tag="ACL8JK_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGS1786247.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            932..1603
                     /gene="sdaAB"
                     /locus_tag="ACL8JK_001377"
     CDS             932..1603
                     /gene="sdaAB"
                     /locus_tag="ACL8JK_001377"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGS1786248.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            1612..2484
                     /gene="sdaAA"
                     /locus_tag="ACL8JK_001378"
     CDS             1612..2484
                     /gene="sdaAA"
                     /locus_tag="ACL8JK_001378"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGS1786249.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            2506..3138
                     /locus_tag="ACL8JK_001379"
     CDS             2506..3138
                     /locus_tag="ACL8JK_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS1786250.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            3188..3535
                     /locus_tag="ACL8JK_001380"
     CDS             3188..3535
                     /locus_tag="ACL8JK_001380"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786251.1"
                     /translation="MKIKEQTRKLAAGCSKHCFKIVDGTDEVSSKHCFKVVDGTDEVS
                     SKHCFEVADRTDEVSSKHCFKVVDGTDEVSSKHCFEVVDRTDEVSSKHCFEVVDRTDE
                     VSNHIRQGDVDVI"
     gene            complement(3621..5471)
                     /locus_tag="ACL8JK_001381"
     CDS             complement(3621..5471)
                     /locus_tag="ACL8JK_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGS1786252.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(5510..6670)
                     /locus_tag="ACL8JK_001382"
     CDS             complement(5510..6670)
                     /locus_tag="ACL8JK_001382"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1786253.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPVTFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINQNMLQ"
     gene            6728..7894
                     /locus_tag="ACL8JK_001383"
     CDS             6728..7894
                     /locus_tag="ACL8JK_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HGS1786254.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLTIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIYILMTVALFTVDRADKIL"
     gene            8033..8359
                     /locus_tag="ACL8JK_001384"
     CDS             8033..8359
                     /locus_tag="ACL8JK_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGS1786255.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            8346..8939
                     /locus_tag="ACL8JK_001385"
     CDS             8346..8939
                     /locus_tag="ACL8JK_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HGS1786256.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            8932..9843
                     /locus_tag="ACL8JK_001386"
     CDS             8932..9843
                     /locus_tag="ACL8JK_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HGS1786257.1"
                     /translation="MRKWTKGFLIFGVVTTIIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            9906..10970
                     /locus_tag="ACL8JK_001387"
     CDS             9906..10970
                     /locus_tag="ACL8JK_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6574 domain-containing protein"
                     /protein_id="HGS1786258.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVSQAEVELESQQEEKIEAPEDSEARTKIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPYQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(11042..11902)
                     /locus_tag="ACL8JK_001388"
     CDS             complement(11042..11902)
                     /locus_tag="ACL8JK_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 family protein"
                     /protein_id="HGS1786259.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIYLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQLEIQPILG
                     QDFKTLAQEK"
     gene            complement(12024..13010)
                     /locus_tag="ACL8JK_001389"
     CDS             complement(12024..13010)
                     /locus_tag="ACL8JK_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGS1786260.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMENLWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(13282..14757)
                     /locus_tag="ACL8JK_001390"
     CDS             complement(13282..14757)
                     /locus_tag="ACL8JK_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1786261.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEVLNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(14841..15764)
                     /locus_tag="ACL8JK_001391"
     CDS             complement(14841..15764)
                     /locus_tag="ACL8JK_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1786262.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(15778..16707)
                     /locus_tag="ACL8JK_001392"
     CDS             complement(15778..16707)
                     /locus_tag="ACL8JK_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1786263.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(17026..17247)
                     /locus_tag="ACL8JK_001393"
     CDS             complement(17026..17247)
                     /locus_tag="ACL8JK_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786264.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            complement(17201..17461)
                     /locus_tag="ACL8JK_001394"
     CDS             complement(17201..17461)
                     /locus_tag="ACL8JK_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786265.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            complement(17887..18042)
                     /locus_tag="ACL8JK_001395"
                     /pseudo
     CDS             complement(17887..18042)
                     /locus_tag="ACL8JK_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
     gene            complement(18804..18971)
                     /locus_tag="ACL8JK_001396"
     CDS             complement(18804..18971)
                     /locus_tag="ACL8JK_001396"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786266.1"
                     /translation="MYAANFSKEKYGFLDKKIYQNLSQSNVGKNFLEVYKEIDTKPKN
                     QISKTLVDKSI"
     gene            complement(18971..20164)
                     /locus_tag="ACL8JK_001397"
     CDS             complement(18971..20164)
                     /locus_tag="ACL8JK_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786267.1"
                     /translation="MTAEIGILNKNGVVLAADSAVTLSDGINSKVFNSARKLFTLSRV
                     HSVGIMIYGDASFMGVPWEVIISEYKKSIGNEVLADTAMYINNFVDFLLQFMPIQSND
                     ALVNYIIRQTRSYLKIIHESTQEIADHRSDQGDVITLEIFKNILWEVIEEYSNDISKS
                     ISETEFEYLDGELDLIREQLDEYFNNNEYSDEQLNFLSKTIYKAMLVGFDRNSVTGLV
                     IAGYGVEEIFPSLRQIELSGVFAKRLVWRVITEKEISQNVACHIIPFAQSEMVDTIMN
                     GIDPMLNAFIGQQINEILESNNISDAQEELFETIARVQQQYYINPIFELIGMQPIDEM
                     ASTAKTFIELTSFKRKIVNTLETVGGPVDVLAISKGEGPIWIERKHYFNIENNIDYKI
                     RKGDI"
     gene            complement(20540..20950)
                     /locus_tag="ACL8JK_001398"
     CDS             complement(20540..20950)
                     /locus_tag="ACL8JK_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HGS1786268.1"
                     /translation="MYELSNRDLDGIDIELGRYRTLASKIYLRRQELIHNKKHSTEDY
                     TGGKGKTVYSPTEATIIRIEEDQTLRYLEGFKLIVDTLMENLIDTDLVIFKMRFLEAG
                     VTWEDVAEKLNKTTRYINSRRKVIAKRFIELKGY"
     gene            complement(21328..21876)
                     /locus_tag="ACL8JK_001399"
     CDS             complement(21328..21876)
                     /locus_tag="ACL8JK_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786269.1"
                     /translation="MDINQVFDTLDDLDNKKSKIYSAREQLSEKRKSLLGIQTVSFEN
                     INSFLSNNLESLEKLEKMEKAINSLQEKYNSDFSEAKAVIFEYIFKETKQRMETKKIY
                     KQYRKKLRRILDAYDEIQELKKDVEEIHTGVVREISQKHSLSLYRTEVSPLTVLPFLN
                     PDISGWMDFSKEYRDIKEYLEK"
     gene            complement(21886..22746)
                     /locus_tag="ACL8JK_001400"
     CDS             complement(21886..22746)
                     /locus_tag="ACL8JK_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HGS1786270.1"
                     /translation="MTTNLVKQKENLEAYIRSTGYNTRGMNVENNHVLIEKPILDSYE
                     DEHQRKELVDLVNVIETRTRGGKYEVTDFESDSLQEISENFVERTESDKKKTISVDYL
                     VKLFSGKLDFSQEQLDDGQYNLTDFLGKKIIKLKRRTRNREIGKILQTAKVQTATSLD
                     DLKSIVSLINPERNVSIVISQSLFSVLEKMKDTSGNYLLKVDKETGTSETFFVDNFLI
                     VDDTTLGNEGDKKGFIGDLENFVTLFDRKKDTLSWVNANDYFRKRLILHTRFDVKKVE
                     EDCGYFIQWN"
     gene            complement(22796..22978)
                     /locus_tag="ACL8JK_001401"
     CDS             complement(22796..22978)
                     /locus_tag="ACL8JK_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000896637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786271.1"
                     /translation="MDPDKRQKIFSQCKKEGDSLEQRKQEILEKYANKQDKPKSRKND
                     SKGSESHKRKTKSKEF"
     gene            22981..23085
                     /locus_tag="ACL8JK_001402"
                     /pseudo
     CDS             22981..23085
                     /locus_tag="ACL8JK_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000505376.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
     gene            23247..24413
                     /locus_tag="ACL8JK_001403"
     CDS             23247..24413
                     /locus_tag="ACL8JK_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS1786272.1"
                     /translation="MQIKQITKKDGSIVYRANVYLGVDKVTGKDVKTSITGRTKKEVK
                     QKTKEAEIAFLQNGSTRFQASNITTYKELASLWWESYKHTVKPNTQLNVRRLLDNHIL
                     PLFGSYKLDKLTTPLIQNIVNKLADKTNKGEEGAFLYYDSLHALNKRILQYGVVMQAI
                     PFNSAREVILPRNTQKAKREKVKHFDNDELKSFLKYLDTLDLSRYRYYYEITLYKFLL
                     ATGCRINEALALSWSDIDLDNAIVHITKTLNYNQELNSPKSKSSYRDIDIDQATVSML
                     KQYKHRQVQEAWQLGRSETVVFSDFINEYPNNRTLQTRLRTHFKRADVPNIDFHDFRH
                     THASLLLNSGIPYKELQHRLGHSQLSMTMDIYSHLSKENAKKAVSFYETALKSL"
     gene            complement(24507..25118)
                     /gene="rpsD"
                     /locus_tag="ACL8JK_001404"
     CDS             complement(24507..25118)
                     /gene="rpsD"
                     /locus_tag="ACL8JK_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGS1786273.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(25313..26365)
                     /locus_tag="ACL8JK_001405"
     CDS             complement(25313..26365)
                     /locus_tag="ACL8JK_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS1786274.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(26362..27060)
                     /locus_tag="ACL8JK_001406"
     CDS             complement(26362..27060)
                     /locus_tag="ACL8JK_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1786275.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(27227..>27658)
                     /locus_tag="ACL8JK_001407"
     CDS             complement(27227..>27658)
                     /locus_tag="ACL8JK_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HGS1786276.1"
                     /translation="GTQTYSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTAN
                     GSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSE
                     DKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT         8265 a         5778 c         4856 g         8759 t
ORIGIN      
        1 tctcatctca aaaaagaagt agagatctat taccaagcga aggaaagata aaaaagccga
       61 gggatttcct cgactcttta catattattt gttcgttagt tcttaatacc agccattgtt
      121 aagccagaag tttttagcag ctgtccatga accgtaacgt cctgcaacgt aggcatctgc
      181 tacacgttct tggttttcag ctgagtagtc accgttcagg tatgaatctg ttaattggta
      241 acgtccgata taacgtccat ttgtagctgt atagctacca cctgattctt tttgagcgat
      301 ccattctttg gcttctgctt cagatccgct tacagttgaa acaactgttt cacttactac
      361 tggagtttct gccactggag ctgaaacagt ttcatcttga gcggctggtg ccgcataagt
      421 agctggcgct ggtgttgcaa caggcgctac agggccatcg ataaccaact cttgatcaac
      481 ataaatcaaa tgaatgttat caatgtggtt gttttctgcc aatttttcaa ctgttgtgtt
      541 gtgagtttca gcgatttctg aaagtgtatc accttcttta acagtgtaag ttgatgattc
      601 ttgagcagat acaaatgatg gagcaaatac tgcaaacaag gcagctactc ctgcaagagt
      661 tgctttaatc tttttagtta ttgatttcat attcgaaaat tctccttctt tctatagttc
      721 tatcataccc tttaaatatt accgtttctt gacactttta tgtagaaata ttacaaaatt
      781 attttttatt tccctaaata aggtgttttt tgtcataaaa gatactattt ttatgctatt
      841 tgaggtatta gaaaggtttt catccacaat taaagccaag cccctcattc tttgatataa
      901 tagagataag aatttttata aggggaaact gatgaaatca cttcgttttc aatctgtctt
      961 tgatatcatc ggaccagtta tgattggccc atctagtagc cataccgctg gtgctgttcg
     1021 tattgggaag attgtctctt ccatttttga tgatactccg acagaagttg aattccaact
     1081 ttttaactca tttgccaaga cctatcgtgg tcacggaaca gacctagccc ttgttgcagg
     1141 tattttagga atggatacag atgatcctga aattccaaat agtctggaaa ttgcccacaa
     1201 gcgtggtatc aagattgtct ggaccattca gaaagacagc aatgcccctc accctaacac
     1261 cactaaaatt actgttaaaa atgcccacaa gaccatcagc gtgactggta tttctatcgg
     1321 tggaggaaat attcaggtaa ccgaactcaa tggttttgcc gtctctctca atatgaatac
     1381 accgactatc atcatcgttc atcaagatat tccaggtatg attgcccttg ttacagaggc
     1441 gctttcccgc tatggtatca atatcgccca gatgaatgtc actcgtgaaa aagctggtga
     1501 aaaagccatt atgattatcg aagttgacag tcgcaactgt gatgaggcta tcgaagaaat
     1561 tcgaaaaatc cctcatctcc acaatgtcaa tttctttaaa taggaggaag catgttttat
     1621 tctatcaaag aattggtcga gcaagcagat ctggactttc aaggaaatgt cgcagaactc
     1681 atgattacaa cagagtttga attgaccggt cgcgaacgtg aagaagtctt ccttctcatg
     1741 gaacgcaatc tggaagttat gaaagcctct gtccaacttg gcctcaatga aaataaatct
     1801 cgtagtggcc tgacaggtgg agatgctgcc aaattggatc actacatcga aaacggaaaa
     1861 actctgtcag attatacgat tctctcggct gcccgaaatg ccatcgcagt caatgaacac
     1921 aatgccaaaa tgggcttggt ctgtgccact ccaaccgctg gaagtgctgg ctgtctgcca
     1981 tccgttctca ctgctgctat tgaaaaatta gacctcagcc acgagcaaca attggatttc
     2041 ctctttgctg ctggtgcctt tggactagtc atcgcaaaca atgcctccat ctcaggtgct
     2101 gagggtgggt gtcaagctga agttggttca gcctctgcta tgagtgctgc cgccttgact
     2161 ctggctgcag gtggaacacc ttatcaggcc agtcaagcta ttgcctttgt cattaaaaat
     2221 atgctaggcc tcatctgtga ccctgttgca ggtttggtcg aagttccctg tgtcaaacgt
     2281 aatgccatgg gagctagctt tgctttcatc gcagcagaca tggccttggc aggtatcgaa
     2341 tctaaaatcc ctgtggatga agtgatcgat gccatgtacc aagtaggagc aagcatgcca
     2401 actgcctttc gtgaaacagc tgaaggtgga ctcgctacca cccctactgg tcgtcgcctc
     2461 caaaaagaaa ttttcggaga ataagcttat caaataggag aaaccatgac ctctatcaca
     2521 gcgatttttt tcgatttgga tggaaccctc gttgatagtt ctatcgggat tcacaatgcc
     2581 tttacctata cctttaaaga gctgggggtg cctagccctg atgccaaaac tattcgtggt
     2641 tttatgggac cacctctcga aagtagtttt gcgacctgcc tgtccaaaga ccaaatttct
     2701 gaagccatgc agatatatcg ttcttactat aaggcaaaag gcatctatga agctcaactc
     2761 tttcctcaga ttatagactt gcttgaggag ttatcgagca gttatccact ctacatcacc
     2821 acgacaaaga atacatctac tgctcaagac atggcaaaaa acttggaaat ccatcatttc
     2881 tttgatggta tttatggttc tagccctgaa gcaccccata aggcagatgt cattcaccaa
     2941 gccttgcaga cacatcaact agcaccagaa caagccatca tcatcggaga taccaagttt
     3001 gatatgctgg gagctcgaga aacaggtatt cagaaattgg ccgtcacttg gggatttgga
     3061 gagcaagcag atctactaaa ctatcaacct gattatatcg ctcacaaacc cttagaagtt
     3121 ttggcgtatt ttcaatagca tagactgggt aacaactcca tttcagaaga aaatgaagta
     3181 atactcaatg aaaatcaaag agcaaactag gaaactagct gcgggctgct caaaacactg
     3241 ttttaagatt gtagatggaa ctgacgaagt cagctcaaaa cactgtttta aggttgtgga
     3301 tggaactgac gaagtcagct caaaacactg ttttgaggtt gcagatagaa ctgacgaagt
     3361 cagctcaaaa cactgtttta aggttgtaga tggaactgac gaagtcagct caaaacactg
     3421 ttttgaggtt gtggatagaa ctgacgaagt cagctcaaaa cactgttttg aggttgtgga
     3481 tagaactgac gaagtcagta accatatacg gcaaggcgac gttgacgtga tttgaagaga
     3541 ttttcgaaga gtataagtct ctacataata aaacgcatat taccaaggtt gtttaacttg
     3601 ataatatgcg tttttctttt ttattcaatg tgggttgttt gattagcaaa ggcgataata
     3661 gcttgcttca actcatctcc actgagagtg cggaactctc caatcttttg attgatggat
     3721 tctaaaggca tgacattaac cttaccaacg aaaatcttat ccataacttg attgtcaacg
     3781 agttcggttg ataccaagag ttcttcgtag agtttttcac ctgggcggat tccaacttca
     3841 acgattggaa tttcactttc agtgtggcca cttagaagca ccatcttctt ggccaagtca
     3901 taaatcttga ctggtttgcc catatcaagg ataaagactt ccccatcttt ggcataagca
     3961 ccagcatgga taaccagacg gctagcttct ggaatggtca taaagtaacg ggtcatgcgg
     4021 aagtctgtca ccgttacagg cccaccttca gcaatctgac gttcaaagac tggaatgaca
     4081 ctaccacggc taccaagaac attcccaaaa cgaactgcac agtaggttga ttggctacgt
     4141 tggttaaagc cagtgacaat caactccgcc acgcgcttgg ttgctcccat aacatttggt
     4201 ggattgactg ccttatctgt cgaaatcata accatcttag acactttagc ttcatcaaca
     4261 gccttagcaa cattgtaagt tccacggata ttgtttttga aggcttcttt tggattgcgc
     4321 tccatcatag gaacatgctt gtgggctgcc gcatgataaa caatagcagg tttgtactgt
     4381 tcaaagactt gcaacaaacg atcatagtct tgaatgtccg caatcacagg tacataatca
     4441 atcccttgga acttacgaat caattcatga taaacaaggt agattgagtt ttccccatga
     4501 ccgagcaaga caatgcgttc aggattgaag cgactaactt gacgacagat ttcagaaccg
     4561 attgaacctc cagctcctgt gactaagatg gtcttacctg tcagttctgc acccagacgc
     4621 gattcgtcaa gacggatttc ctgacgaccc aaaaggtccg taatatcaat tttttggaag
     4681 ccagtacctg cttggtgaag gccctgaaca acagtttcaa ccttaggcat cttgtaacat
     4741 ttgacaccca gcttattaca catctgcaag atacgctcat attctgacgg atccagcgac
     4801 ggaatcgcaa cgatgacacg ctcgatttga tggcgtttgg ctaattcagg cagattgtca
     4861 taagagccca aaacaggaat accaccaagt ttttgaccct ttttcttaga atccttatcc
     4921 aaaataccga ccagttctaa ttcactggtt ggatgttggt aactatccat aaagagagcc
     4981 ccaccatcac cggcaccaat caagaaggtc cgacggtgtt ctccatcacc actacctttt
     5041 ttgcgtctgg agtagattaa ctgccaagta atccgtggca ataaaatcaa gaaggtactc
     5101 aacaagataa agagaatgat aaaacggatg gagaagagtg gcaagaaggc ataacagata
     5161 ctatatgaca agacactgct agcagtcaca ccaaaaaaga ttttcatgaa atccgtaatc
     5221 ttgctgtaac gactaatgct cgcgttcaac ccccaaaaac caatcatcaa ttgatagaac
     5281 aggaaggcca aactcgtata gataatgtag tcaacaggtg ctggattaat cagcccataa
     5341 aataaaatat aagatacaat tatggaaacc accatactga aaatatcaaa tattccccag
     5401 aaaacctgct tttgttgttt atttaaaatt tccaccagat caatcacata atctgttagt
     5461 tttttattca tagaaatcta ctcctcctta aaagagtttt actatattgt tattgtagca
     5521 tattttgatt tatttggctt attttatcca aataaattat tgttctcttg tactccttct
     5581 tccatttaaa tcctctaatt aaacctacaa tcgtcccaag gccataagca aagtgaatgg
     5641 aaaataaaag aaagggcatc acaattagaa atccattttt atgttttaat aaagtcagca
     5701 aagtgagtaa tgacaaaagt agaaaatagg cacctaatag taaagttatg aatacgaatg
     5761 tgaccggtaa caatgctaga ctaaacacaa gactcaaaac aaataaacaa ggaacatagt
     5821 gaaataatga taaacactta aactgaacat gacttgtcaa gccaatccac aaaccatttg
     5881 aatacttttg atgcagcatt ttcttgaatg ttggtcgaat atactgataa gatagaatac
     5941 ttgggctata gcggatttta taaccatgtt ctcgaattct ataatgaata tcattatctt
     6001 cagttcggcc aagttgctca tttactaaac caaccttctg gaaaacctct cgtttataca
     6061 tcccatgaaa aatagaagaa acatatctat cctcggaact atttcgataa ttggcaatgc
     6121 tactgccaaa catattttcc tcaacaagat gcaaggtctc tgcccatttt ccttttcctt
     6181 cgacaatcgt cggtctaggc cccccacaga caaattcacc ttgttgaata atagccacat
     6241 tgttcattac aaaactctca gtaacttttg aatgagcatc aatttttaaa ataaggtccc
     6301 ctacagaatg tttaactccc aggttaaaac cactagcttg atttttctta ggattgttat
     6361 acaatctaat tgagttaaac tctgtatctt cctttataaa ttgctgaatg atagctgtgg
     6421 tcccatctgt ggacatagca tttataaata gaatttcaat attctcttta ggataggttt
     6481 gattttttaa gtcttcaatt agaccaggca gatatttttc ttcattgtat gcactgatta
     6541 caatggatac gagaagactt tcaacatttt gagtcactac tactctcctg aatttttcct
     6601 tccaccattc tatcataatt ttcaagactt tcccattttt atcttgaaag ccagaaacct
     6661 tacttgacat tatagtgaaa aagccttaaa ataagctgtt attaaaatca gctataagag
     6721 gtattatatg aaaaagcaat cactcttttt tgttccaggt attatcctga ttggtgtttc
     6781 cttgcgaact ccttttactg ttttacccat tattttggga aatatttcgc aaggtctaga
     6841 ggtagaagtt agttcgcttg gtgtcttgac cagcctgcct ctccttatgt ttaccctctt
     6901 ttcaccattt tctacccaac tggctcagaa aatcggcttg gagcatctct tcacctacag
     6961 cctcttcttc ttgaccatcg gctcacttat tcgactaatc aatctgcccc tactctatct
     7021 aggaaccttg atggttgggg caagtgtcgc agtcatcaat gtcctgcttc ctagtcttat
     7081 ccaagccaat caaccaaaga aaattggttt tctgaccacc ttatatgtaa cgtctatggg
     7141 gattgcaacg gctctggctt cctatctagc tgtgcccatt acacaagcca gttcttggaa
     7201 aggacttatc cttctcctca cgttactctg tctagcaact tttttggtct ggctcccaaa
     7261 tcaccgctat aatcatagac tagctccaca aaccaaacaa aaaagtcaaa taaaggtcat
     7321 gcgtaataaa caggtttggg caattattat cttttcaggt tttcaatcct tgatctttta
     7381 caccgtcatg acctggttac ctaccatgtc tatccatgca ggtctatcca gtcacgaagc
     7441 tggcttgctg acttctatct tatctctgat tagcattcct ttttcaatga ccatcccaag
     7501 cctgacaacc agtttatcta ctcgcaaccg tcagctcatg ctcactctgg tttcactagc
     7561 tggtgtggtc ggcatttcca tgctcttttt cccaatcaat aatttcattt actggcttac
     7621 catccatctc ctcatcggaa ccgcaaccag cgccctcttc ccttatctca tggtcaactt
     7681 ttcactcaag acaagcgccc ctgaaaagac agcccaattg tccggcctat ctcaaacagg
     7741 aggctatatc ctagcagcct ttggaccaac cctctttggt tacagttttg acctgttcca
     7801 ctcttgggta ccagctgtag ctgccctctt gctcatctat atcctgatga ctgtggccct
     7861 ctttacagtg gacagagcgg ataagatcct ttaaacttct agttttagct agaagttttt
     7921 tatatataaa aattttacac atttctcttg acagggcttt cttttagatg tacaatgtat
     7981 gtgtagaaaa attatatata aaaatcttac acattagaaa aggaggtttc ccatgtactt
     8041 tccaacatcc tctgccttga ttgaatttct catcttggct gtactggagc agggtgattc
     8101 ttatggttat gagattagcc aaaccattaa gctgatcgct aatatcaaag aatccacact
     8161 ctatcccatt ctcaaaaaat tggaaggcaa tagctttctg acaacctatt ctagagagtt
     8221 ccaaggtcgc atgcgcaaat actactcctt gacaaacggt ggtatagagc agctcttgac
     8281 cctaaaagat gaatggacac tctatacaga caccatcaat ggcatcatag aagggagtat
     8341 ccgccatgac aagaactgaa tacctgactc agctagaact ctatctcaag aaactacctg
     8401 aagctgaccg tatcgaagcc atggactatt tcagagagct ctttgacgat gctggagtcg
     8461 aaggagaaga agaactcatc gctagtttgg gaactcccaa agaagcggcc cacgaagttc
     8521 tatccaatct tctcgataaa aaaatcaatg aagcacccgc tcaaaaaaat aaccgacaaa
     8581 ttttacatat cgccttgtta gccctccttg cagcacctat cggcattcct ctgggaatcg
     8641 ccatcctcgt gaccctgttc gcaatccttg tagccgcttt gactgtcatt ctggctttct
     8701 ttgcagtttc catactgggt atcatcggcg gattcctatt tttagttgaa agtttcacta
     8761 tcctcgccca agccaaatca gcctttatct tgatttttgg ttctggttta ctggctatcg
     8821 gtgcttcttc gctagtttta cttggcattt cctatgtagc tcgcttcttc ggtctactca
     8881 ttgttcgtct ggtacaattt gttcttaaaa aaggaaagag aggtaatcag catgcgtaaa
     8941 tggacaaaag gatttctcat ctttggtgtg gtgactacca ttatcggctt tatcctgctt
     9001 tttgtaggta tccaatctga cgggattaag agcctacttt ccatgtccaa agaacctgtc
     9061 tatgatagcc gtacggaaaa gctaaccttt ggcaaggaag tcgaaaacct agaaattact
     9121 ctccaccaac acgcgctcac catcacagac tctttcgatg atcaaatcca catttcttac
     9181 catccatctc tttctgctca ccatgatctt atcaccaatc agaacgatag aactctgagt
     9241 ctcactgata agaaactgtc tgaaactccg tttctctctt ctggaattgg tgggattctt
     9301 catatcgcaa gtagctactc tagtcgtttt gaagaagtta ttctccagct accaaaaggg
     9361 agaactctaa aagggatcaa catctcagcc aatcgcggac aaaccaccat cataaatgct
     9421 agccttgaaa atgcgaccct caatacaaac agctatatcc tccgaattga aggaagtcgt
     9481 atcaaaaaca gtaaactcac aacgcccaat atcgttaata tctttgatac agttcttaca
     9541 gatagtcagc tagagtcaac agagaatcac ttccacgctg aaaatatcca agtccatggc
     9601 aaggttgaac tgactgccaa agattatctc agaatcatcc tagaccagaa agaaagccaa
     9661 cgaattaact gggacatctc aagcaactat ggttctatct tccaattcac aagagaaaag
     9721 cctgaatcaa gaggtacgga attaagcaac ccttacaaaa ctgaaaaaac cgatgtcaag
     9781 gatcaactca ttgcgagatc tgatgataat attgatctaa tatccacacc aagcagacgt
     9841 tgacaaaaac gcttacatct gctactatga aagcatattt atctaactaa aaaggaggtt
     9901 ctaccatgaa acaagaatgg tttgaaagta atgattttgt aaaaacaaca agcaagaaca
     9961 agcctgaaga gcaagctcaa gaggttgcag acaaggctga agaaacgata gccgatctcg
    10021 atacaccaat tgaaaaaaat actcagttag aggaggaagt ctctcaagct gaagtcgaat
    10081 tggaaagcca gcaagaagag aaaattgaag ctcctgaaga cagtgaagcg agaacaaaaa
    10141 tagaagaaaa gaaggcatct aattctactg aagaagagcc agacctttct aaagaaacag
    10201 aaaaagtcac tatagctgaa gagagccaag aagctcttcc tcagcaaaaa gcaactacga
    10261 aagagccact tcttatcagt aaatctttag aaagtcctta tatcccctac caagctccaa
    10321 aatctaggga taaatggaaa gagcaagtgc ttgatttttg gtcttggcta gtggaagcga
    10381 tcaaatctcc tacaagtaag ttggaaacaa gtatcacaca cagttacaca gcctttctct
    10441 tgctcattct gttttctgca tcttcctttt tctttagtat ctatcacatc aaacatgctt
    10501 actatggaca tatagcaagc attaacagtc gcttccctga gcagctagct cctttaactc
    10561 ttttttctat catctctatc ctagtagcga caacactctt cttcttttca ttcctcttgg
    10621 gtagtttcgt tgtgagacga tttatccacc aggaaaagga ctggacgcta gacaaggttc
    10681 tccaacaata tagtcaactc ttggcaattc caatcttcct cactgctatt gctagtttct
    10741 ttgctttctt tgatagccta cgatttacag ctctcttgtg tgtaattagc attggaatca
    10801 ttctgcttgc cagtctccat atcattacaa gaccaagtca agcaagtgaa accgactcct
    10861 tctatcaatt attcttgtct gtccttgtga acggagttat tatcctcctc ttctttgtag
    10921 ctgaagtggc actgattgga gattatcttc gtatcttggc ctttctttaa aattcaatcc
    10981 tgtcatcctt ggcaggattt tttctatgtc aaaaaagcaa gtcgattgac ctgcttctgc
    11041 tttacttttc ttgtgctaat gttttaaaat cttgtcctag gatgggttgt atttctaatt
    11101 gattggcgtc tagctggtgg taaaaagatg ggggtaacac ctctaagaat tttgcatagt
    11161 ccaagcgagc tatggattca tagtcttctg gtttagagcc gtctcctgtg atttgaacca
    11221 agtaaatctc ccactggact tccttatcca ccaattgctc aatataggct gcaggaacaa
    11281 acggttctct cggtaaaact gtcttgactc cttgagctaa atggtaaacg ccatgcactt
    11341 ttccttctcc atcctgatag aaggaaactc ttgcaaagta ggcatctgtc tcttgaaccg
    11401 cacgcacacg cgcttcaaac tgagccaagc catctgcctc taaaaagctt ttcaagttct
    11461 cacgactaaa gaaaatagga ttaaaaattc cttggcaaat cgtaaaacga gctacagggt
    11521 ctgctagata ggcttgaata cttgcttgga aataagcttc aaaatcaaaa ccatctagcc
    11581 cttcaatatc agtccctgta taagcaagca aagcatctaa aaatgacttg ataatctgcc
    11641 agtctgtctt tgttagtagg tcaggaagat cgacacggta agccttttga ccatcagcat
    11701 aactgacctt aaagagaaat tgtgattgcc ccactatcgc acactcaata tactcgagac
    11761 gattaagagg ctgacgaaga tagactacat catagctatg tgactccaaa ccgtctagca
    11821 aggccaagat cgacttggca ttcaaaatct cttgttctcc taaaatgctc tgtttatttg
    11881 gaataaaaaa tgtttttgcc ataactggac tcctttgaaa tcgtttacat acagtatacc
    11941 ttattttcct gaaagataca aaaacaaact ttagattttt gagtacaaag catagaaaaa
    12001 cagcccctga ggactgtttg atcttataca gtagctgcct gatccaagct ttcaccgata
    12061 gcggctaggc gctcaatcac ttcagcttgt gtcaattcat tttttgaaac atagcggtta
    12121 cgtgggtgaa cacgacactc gtgtgagcat ccacgaaggt acttgtcttc attttcttct
    12181 gatgtcaaga tacgacggtt acagaaggga tttccacagt tgacataacg ttcacatggt
    12241 gttccatcaa accagtcttt ccctacgatg gttgggttga catggttgac atcaacggca
    12301 atacgctcgt caaagacgta cattttccca tcccaaagct caccttgaac ttctgggtct
    12361 ttaccgtaag ttgcgattcc tccgtgcaat tggccgacat ctttgtagcc ttcacggacc
    12421 atccagcctg agaatttctc acagcgaacg ccacctgtac agtaaaccac gacacgcttg
    12481 tccatgaatt tttccttgtt atcacggacc cattgtggta actcacggaa gttgcgaata
    12541 tctgggcgaa tagccccacg gaaatgtcct aggtcgtact cataatcgtt acgtgtgtca
    12601 aggacaacgg tatctttatc aagaagcgct tctttgaact cttttggaga caagtaagca
    12661 cctgttgttt caagtgggtt gatgtcattg tcaaagtcgt tgtcttccaa accaaggtgg
    12721 acaatttctt tcttgtagcg aacaaacatc ttcttgaagg cttgttcact ttcttcgtca
    12781 atcttgaacc agagattttc cattcctgga aggctgtgaa cgtagtccat gtatttttga
    12841 gttgtttcat agtcacctga aactgttccg ttaattccct cgtcagcgac taggatacgg
    12901 cctttaaggc cgattgattt acagaaagcc aagtggtctg cagcaaattg ctctgcattt
    12961 tcaattggag tatagaggta gtaaagtaag acacgaatat cttttgccat aagatttgtt
    13021 ctcttttcta ttcttaaatt ttctaaattt tttatttatc catactagta tacctgcttg
    13081 agaaaacgaa tgcaatttat ttgactggaa attgtagagg gttctcgaaa tttcctgaat
    13141 ggttaaaata aggacaagag aaaacatgga tatctatatc cttgtgccaa aaaaaccact
    13201 gccctcccca gaccaacctg aggaaagcgg tgattcttat tttaggagtt aggaatgaat
    13261 acacgaaatc aatttagctg attatttttt gtttttcaag aattcatcgt attgtttttg
    13321 catttcgttc aatacttttt cgtaggcacc ttcagatttc aatttttcca tcaattctgg
    13381 aatagcttta tctgggtcta cagtaccagt gttgatagct gtatcaaatt gttgcattgt
    13441 gttagcaata gctgagattt cagatttcac attgtcagta ttgaagataa atccaagcgc
    13501 tggagattct ttagcttctg ccaattcttt cttagaattt tcgatttgtt ggtctgtaac
    13561 gttttcgttg atgtaaagga tccagttgtt accagtgttc catccaccca tgtgagtgtt
    13621 tcctttgtag ccatcaagaa cgcgaacacg attttcttta ccttcaattt tttcccagtt
    13681 cttgccttct ggaccgtaaa caagaccgtt caagagttct gggttcgtat tcaagaggtt
    13741 caacacttcc attgattttt ctttgttctt agagttgttt gagatgacaa agttagcaac
    13801 ttgtgttgtt tggtttttct tgatgaagtt agtaattggt ttgatttgga tatctttgtt
    13861 ggcaacacgt gaaagcaagc tgttaccgta gtcagctggt cctactgttt cttcacgaac
    13921 gaaccaagta tcttgttgaa ggtcaaatga agtatcgctt gttgcgacat cttttggaat
    13981 gtagccagct tcatagaatt tgtgaagagt cttcaagtgt tctttgaaac gaggcacttc
    14041 gtaacggttt acaactttag tagtatcgcc ttcaagatca ataacgaatg gaagcccgtt
    14101 tgctactggg tagtcaaagt tatcagatgg gatgaaaact ttaccaatag caaatggtac
    14161 tacgtctgga gctttttctt taatttgttt caagactggc tcaagagttt cgtaagaagt
    14221 aacacctgaa atatcgatac catatttggc aaggagagtt ccgttgaagg caaagttttg
    14281 agatgatgca acgttggctg caactggaac agcgtaaatt ttaccgttta cagtattacc
    14341 cttgatgtaa gctgggtcaa gtgccttgta aaggtcttta ccttcttttt tgtacaattc
    14401 tgtcaagtca gcataagcac ctttttgagc atttacaata tagttatctg caaaggcgat
    14461 atcatagttt tcaccagatg atgtgataac tgacattttc ttaccatagt caccccagcc
    14521 aaggtattgg atatccaatt tggcaccaac tttttcttcg atgattttgt tggcatttgc
    14581 taacaattca tccaagttat ctggtttgtc accgatttgg tacattttga taacaggttt
    14641 gtcacctgaa tcagcagctt ttttgctgtt acctgtcaaa tttccacaag cagcaagacc
    14701 tgcagccaaa gcgactacac tagcagatgc aaaagcatat tttttccagt ttttcatgat
    14761 aaaaactcct ttttttattt ttaaacttat aaacaatgta atgatcttaa cttcacgcaa
    14821 gggaagtttg gaaacaagtg ctattctttc acaccaccga tagtcaaacc ttttacaaag
    14881 tagcgttgga aaaatggata caaaatcgcg attggaaggg ttgcaaccac aaccatggcc
    14941 atacgacctg tttctttcgg tagagcaact cccagttgac cagtcaagcc gaccgctttg
    15001 gcaatgtagt ccatattttg ttggatttgc atgagcaaat attgcaatgg atacaagttg
    15061 tcactcttga tgtaaagaag ggcgttgaac cagtcattcc agaaaccaag agctgttaag
    15121 agcgtgatgg ttgcgatacc tggtagtgac aatggcaaac agatttggaa gaaaatccgg
    15181 gcttcactgg caccatcgat acgagccgat tctagaatgg cttctggaat ggtcttcttg
    15241 aagaaggaac gcatcaagat gatgttaaat ggtgagagaa gcattggaac aatcaaggcc
    15301 caaacagtat ccccaagctg aagtacacgg gtcaccatga tataacctgg taccaaacca
    15361 gcgttgaaca acatactgag aaggacgaag atggtaaaaa atctgcgata cttaaaggtt
    15421 gtccgtgaaa tagcgtaggc ataggttgtt gtgataaaga catttgtcaa tgtcccaact
    15481 acggttacaa agacagagat gaagagggct tgtaggattt tatccttaaa ctgtgccaaa
    15541 aactcaaaac cgtctaagcc aaattgggat gggaagaagc tatagccgta ttggaggagg
    15601 cttttctcgt ctgtcactga aataatgata acgaatacaa aaggtaggat acaagagagg
    15661 gcaatcaaac ccgaaatgat actgaagaag atatctgctt tcttactgaa ggagtgaatg
    15721 ccgacattat caattttttc ttttttaatt ttcttttttg ccatattctc ctcctttcta
    15781 gaacaaagct gagtttggat cgactcgtct tgcaagcaag tttgatagga taaccagaat
    15841 caaaccaaca acggattggt aaagaccggc tgctgcagcc ataccgatat ctgctgtctg
    15901 agtcaaacca ttaaagacat atacgtccaa aacgttggtt acattgtaaa gctgaccagc
    15961 attgtgtggg atttgataga agagaccgaa gtctgcgcgg aagatatttc cgactgcaag
    16021 gatggtcaat acagttacaa gcggagtcaa ctgaggaatg gttacgttgc gaatacgttg
    16081 ccacttgcta gctccgtcca ctgtcgctgc ttcgtagtag gttggatcaa ttcccatgat
    16141 cgtcgcatag tacatgacac tgctatatcc aaagcctttc caaataccta ggaaaagtag
    16201 gagatagggc cagatgccca ggtcagcgta aaaattgact tctttgagac caagactttc
    16261 caatagatga ttgaacaccc ctttatcaat atttaggaag gcatctgtaa agaaactgat
    16321 gataacccaa gacaagaagt aagggaacaa catagaagtt tggaaaatct tcaccattct
    16381 cttagaacgg agctcgctga ggataatggc aatccctaca gatacaacta aacctagaaa
    16441 gataaagcca agattgtaga ggacagtatt tcgtgtgata ataaaggcgt ctcttgaact
    16501 aaataagaat ctgaaattat cgagtccgac ccatttacta tttatgatac tatctatgaa
    16561 accattactg gtcatgtggt agtctttgaa ggcaaccacg ttcccaaata ctggaatgta
    16621 aaagaataga atcaaccaga gtgcccctgg caaaaccatc aagagaaaga tccagttgtc
    16681 tctcaatgtt tttgaaaact ttttcataat ttcctccctt tttattttga tatccatcta
    16741 aaaattcttt tttagacttt tgataacgat tacattatta gtatactcct atttgtaggt
    16801 taggttaaac tcctaattat agaaaaaact ccacaaatta tgtagcagat ttaaaacttt
    16861 atcaccacta tcaaacaaat gtcctaaatc aattgtttat tttatctcta ttagcccagt
    16921 gatggcgtca ctctgttata aacatccaac aacgggggat actgaaaaat ctccagacta
    16981 gggaactcag cgatagttcc taatctggag atttttaata tgttattagg cgtttgcttt
    17041 caacttagca ataacctctt taagattatc aatcacctct gcttcagtat gctcagagcc
    17101 tttttcatct gccaagaaca aaactgcttt ttgaagttct ttttgagagt tttcaaggac
    17161 atccttatct actgtttcaa ggtttgagtc tttaagaagt ttacttaatt ccttggctaa
    17221 tttcttgagt ttgatttgca gactcatctt ctcctgctgt ttctttgccc gctgtttgtc
    17281 ctccatcctt agttgctgac tggctttcct taatggactc tagggaagca atggcatctt
    17341 tgactgtttg caagatatca cgtaaacctt gctctgtcaa actatcatct gcaaaagctt
    17401 tcttagcctc tgccaaaacc agacgtgctg aatctgtggt aggattcgat acacctgtca
    17461 atgatctcaa aagattttct aaggtttgag tctgcttact aatactagac taaaatcaaa
    17521 aagtattata taacagtgat atgaaatcaa ctaaagaaga aatccaaacc atcaaaacac
    17581 ttttaaaaga ctctcgtaca gctaaatatc ataaacgcct tcaaatcgtt ctatagtaaa
    17641 atgaaacaag aacaggacaa atcgatcagg acagtcaaat cgatttctaa caatgtttta
    17701 gaagcagagg tgtactattc tagtttcaat ccattatatt tcgtctgatg ggcaaatctt
    17761 ataaagagat tatagagctt ttatagtagt ttgaaataag atgtgaacaa ctctatcagg
    17821 aaagtcaaat taatttatag aaatatttta gcagccaagg tgtactgtta tagattcaat
    17881 acactatact tggtggttta gctctcctgt tttctctttt agctttaacc agccataaat
    17941 ggtattacgt gagatttgga aaacgtgtga tgcttctgtt atactacctg ttcgctcaca
    18001 ataagagaga acttttttac gaaaatctat tgaatatgcc ataaaaggat tataccacat
    18061 tgtgtactat ttttggttca ttttactata tcactttgga ctatatcggt ctagttatgt
    18121 ctcaacgatt atagctggat actaagagaa atcaaaaaag cactctagga tagaggccta
    18181 aagtgcttag tttcaaggct ttacagccta tcatatttaa taaaatatta caacattttg
    18241 ttgtatcgct tttttaagta ttcagcaagt agctttatta cttcttaatg cttgataata
    18301 gggtgatggg gagttttcac ttttcgtttg aacgttttgg agtttctccc ttactccaca
    18361 aatcactgaa catgataaac gagttcagca ggcaagaaac tagcactatt taaaagtgct
    18421 tttttgtttc tatttaatag gaagctattg cacatctttt aatatttgtt ttattagttt
    18481 gcatgaagca ttctaaatac tcttcatctt ctaatctaaa atctaacaat agcataaatt
    18541 taatttcgta tctgttctgt tatattggaa ctctatatgt acctgttctt taatcttcaa
    18601 agtttagctt agattctttt ttgattgtaa gtttagtatt ttaaaactgt gtttttcctt
    18661 cttctttaat aattaatcaa atatagtaaa aacttatcct agcgctaaca taaagttgtt
    18721 attataaatc tctttttatt ttaaaatcat agtaacaatc atatttaagc aaaaacactt
    18781 agaacaatct aagtgttttc attttagata gacttgtcaa caagagtttt actgatttga
    18841 ttttttggtt tagtgtctat ctctttatat acttctaaaa aatttttccc aacattactt
    18901 tgtgaaagat tctgatatat ttttttatct agaaatccat atttttcttt tgaaaaattt
    18961 gctgcataca ttatatatca ccctttctaa ttttataatc aatattattt tcaatattaa
    19021 agtagtgttt tctttcaatc cagataggac cttccccttt agaaatagct aaaacatcca
    19081 ctggtcctcc aactgtttca agtgtattca caatctttct cttaaaagaa gtcaactcaa
    19141 tgaatgtttt tgcagtagaa gccatctcat caataggttg catcccaatc aactcaaaaa
    19201 ttggatttat ataatattgt tgttggactc tagcgatagt ttcaaacaac tcttcctgtg
    19261 catccgatat attattactt tccaaaattt cattaatttg ttgtcctata aatgcgttta
    19321 acattggatc tatgccattc attatagtat ctaccatttc ggattgagca aagggaataa
    19381 tatgacaagc aacattttgg ctaatttctt tctcggtaat tacacgccag acaaggcgtt
    19441 tagcaaatac accacttaac tctatttgtc taagggatgg aaaaatttct tcaacaccat
    19501 acccagcaat taccaaccct gttacagaat ttctatcaaa accaactaac attgctttgt
    19561 atattgtttt agataaaaag tttagttgct catcggagta ttcattattg ttaaagtact
    19621 catctagttg ttcccgtatt aaatcaagtt cgccatctaa atattcaaat tcagtttcag
    19681 atattgattt ggagatatca tttgaatatt cttctataac ttcccataaa atatttttaa
    19741 aaatttctag agttattaca tctccctgat ctgatctatg atcagctatt tcttgggtgc
    19801 tctcgtgtat tatttttaaa taacttctag tctgtctaat tatataatta accaaggcat
    19861 cattactttg tattggcata aattgcaata aaaaatcaac aaaattatta atgtacattg
    19921 ctgtgtcagc tagtacttcg ttgccaattg actttttata ctcacttatg attacttccc
    19981 acggtacacc cataaaggag gcatctccat aaatcataat tccaaccgaa tgcactctag
    20041 ataaagtaaa taatttccga gcactattaa acactttgga gttaatcccg tcagataaag
    20101 tcaccgcgct atctgcagct aaaacaactc cattcttatt tagtattcca atttctgcag
    20161 tcaaaattga gcctccaatt attttacata acttaacagt taaaaatcat taaatatttt
    20221 tcaatttata caacaattcc ctttaactaa ttataataca attcatacta aaagtacatt
    20281 cttttaacta tgcaaacaca tctccaattt ctaacaatat atcatagctt cactttaatc
    20341 tagaaaaatt atcttcagtt taacctcctc atttatttca atgacttttg aatgcatatg
    20401 tttaatttca aaaaactagc cttcacctta taaatcaaca agtttttacc ccctttttgt
    20461 ctggaggtct ccgacttaga aaaagttccc ttcaccggtt ctcaaagtat tcaaaaaatt
    20521 tttttcaacg tggggggagt caatatcctt tcagttctat aaatctttta gcgattactt
    20581 ttcttcgact atttatataa cgagtagttt tatttagttt ctctgccaca tcttcccaag
    20641 tcacaccagc ttctaaaaat ctcattttaa agatgactag atcagtatca atcagatttt
    20701 ccatcaaggt atctacaatt agtttgaaac cttctaaata tcttagtgtt tggtcttctt
    20761 caattctaat aatagttgct tcggtaggac tatatactgt cttgcctttt ccaccagtat
    20821 aatcttcagt gctatgtttc ttattatgta tcagttcctg tcttcttaaa taaattttac
    20881 tagcaagcgt tctatatcgt cctaactcaa tatctatccc gtccaggtct ctgttactca
    20941 actcgtacat aggcaagtac ctccacttaa atttaaaaat ttttttatct ttcaatttgt
    21001 caaattgtaa attctgtcaa actgacaaaa agcgctaaaa gccttccaac actccactta
    21061 ccaggtatca ttgttttaag tttgacaact cttcaatatg acaagttcaa gggaaatttc
    21121 tttaatttat cccctaagtt tctcatatct tacattctgt gaaactcact ccattctgta
    21181 acttactgat atatatgact tccaagccta tactctattt tagtttatgc ttactttgtt
    21241 atgtgaaact tagtaaagca taaaagtagg actagcgata tctcttctgt ttcagccata
    21301 tatcactagc cttacttaat ttgttcccta tttttctaaa tactctttaa tgtcccgata
    21361 ttccttagaa aaatccatcc acccgctaat atcagggttt aagaatggta ggacagtaag
    21421 cggacttact tccgttcgat atagcgatag agaatgtttc tgacttattt ccctgactac
    21481 acctgtatga atttcttcta catccttctt tagttcttga atttcatcat atgcgtccag
    21541 aattcgtcta agtttctttc ggtattgttt atagatcttc ttagtttcca tccgttgctt
    21601 agtttcttta aaaatgtatt caaagatgac tgctttagct tctgaaaaat cactattata
    21661 tttttcctga agagaattaa tagctttttc catcttttcc agcttttcta aagattctaa
    21721 gttatttgac aaaaaagaat ttatattctc aaatgaaact gtttgaatgc ctaaaagact
    21781 cttccttttt tcgcttaact gttctcgtgc tgaataaatc ttactttttt tattatctaa
    21841 atcatccagt gtatcaaata cttgattaat atccatttct tcctcctagt tccattgaat
    21901 aaagtaacca caatcttctt caactttttt tacatcaaat cgggtatgta aaatcaaccg
    21961 ttttctaaaa tagtcattcg cattcaccca actaagtgta tctttctttc gatcaaacaa
    22021 agtaacaaag ttttctagat ctccgataaa tccttttttg tcgccttcgt tccctaatgt
    22081 cgtatcatct acaattaaaa agttatctac aaagaatgtt tcactcgttc ctgtctcttt
    22141 atcaacttta agaagataat ttcctgaagt gtctttcatt ttttctaaga cactaaatag
    22201 tgattgacta ataactatag atacattgcg ctctggattg attaaagaaa caatagattt
    22261 caagtcgtcc agacttgtag cggtctgtac tttcgcagtt tggagaattt tcccaatctc
    22321 tctatttcgt gttctacgtt ttaatttaat aatcttctta ccaagaaaat ccgttaaatt
    22381 atattggcca tcatctaatt gttcctgtga aaaatcaagt tttccactga ataatttaac
    22441 taagtaatca acgctgatag ttttcttttt atctgattct gttctctcaa caaaattttc
    22501 actaatttct tgtaatgaat cagattcaaa gtcagttacc tcatacttcc cgccacgggt
    22561 acgagtctca ataacattta ctagatcaac cagttcttta cgttgatgtt catcttcgta
    22621 actatcaagg attggttttt caatgagtac atgattattt tctacattca tccctctagt
    22681 gttataacct gtacttcgga tataagcttc taaattttct ttttgtttaa ctaagttagt
    22741 tgtcattttt ttgctccttc atcttttaat atctgatttt tgtttataat tttttctaaa
    22801 attctttgct cttagttttt cttttatgac tctccgagcc tttagaatca ttttttctag
    22861 attttggttt gtcttgtttg ttagcatatt tctctagtat ttcttgtttc cgttgttcta
    22921 agctatcacc ttctttttta cactgagaaa agattttctg tcttttatct ggatccatag
    22981 aaaacttatc acctgcatac catcacaacc gccaatggtg gaagcaaagg tttaggcggt
    23041 ggtgaccgca ttcaagccac aatggtattt gagaagatta tctaattaat accctttata
    23101 agttccataa tcgcttcatt ttcttacctg gtacatttta ccgttcgttc tcttaaaatc
    23161 gaaaatagag gggttctcgt agctcctagc atggtataaa ctcaaaacct tttctaattg
    23221 cttgcctgct gatggaaaag aatactatgc aaataaaaca aatcacaaaa aaagacggtt
    23281 caatagtata tcgtgctaat gtctatcttg gtgttgataa agtcactgga aaagatgtaa
    23341 agacaagcat aacaggaagg acaaaaaaag aagttaagca aaagacaaaa gaagctgaaa
    23401 ttgctttttt acaaaatgga tctactagat tccaggcttc aaatattact acttacaagg
    23461 aattagcttc cttatggtgg gaaagttaca agcatacagt aaaacctaac acacaattaa
    23521 acgttagaag actgctagat aaccatatct tacctttatt tggctcttat aagttggata
    23581 aactaactac tccacttatt caaaatatag tcaataaact tgctgacaaa accaataaag
    23641 gggaagaagg cgcttttcta tactacgata gcttacacgc tttaaataag cgtattttac
    23701 agtatggtgt agttatgcaa gctataccgt ttaattctgc tcgtgaggta atattacctc
    23761 gcaacacaca aaaagcaaag cgagaaaaag taaagcactt tgataatgac gaattaaaaa
    23821 gctttcttaa atacttagat actctggatc taagtaggta tcgctattat tatgagatta
    23881 cactttataa gtttctactt gctactggtt gtcgtatcaa tgaagcttta gccttatcat
    23941 ggtctgatat tgacttagat aatgctattg tgcatatcac aaaaacacta aactataatc
    24001 aagaactcaa tagtcctaaa tcaaaatcta gctatcgtga tatcgatata gatcaagcga
    24061 ctgttagtat gctgaagcag tacaaacata gacaagtaca agaagcttgg caacttgggc
    24121 gctctgaaac tgtagtcttt tctgacttca taaatgagta ccccaataat cgaactctac
    24181 aaaccaggtt aagaactcac tttaaacgtg ctgacgtacc taacattgat tttcatgatt
    24241 ttcgccatac tcacgctagt ctcttgctta actctggaat accttacaag gaacttcagc
    24301 accgtctagg acattcccaa ttatctatga ccatggatat atacagtcac ctctcaaaag
    24361 agaatgcaaa aaaagcagtt tcgttctatg aaactgcact aaaaagttta taactgaaca
    24421 aataactgaa caaacccaga aatcaacatt ttaagacaaa gcaaaaagcc cactgttgta
    24481 ggctttctgt aagatatttc ttaaaattaa agcattttgt tgtagaattc aacgacaagt
    24541 gcttcgttga tttctgggtt gatttcgtcg cgttctggca agcgagtcaa tgaaccttcc
    24601 aatttttcag cgtcgaatga tacgaatgct ggacgtccaa gagtagcttc tactgcttca
    24661 aggattgctg gaactttcaa tgatttttca cgaactgaga tcacttgacc tggagttacg
    24721 cggtatgatg ggatatcaac gcgtttcccg tcaacaagga tgtgaccgtg gtttacgaat
    24781 tgacgagctt gacgacgagt agtcgcgaga ccaagacggt aaacaacgtt atccaaacga
    24841 cgttccaaaa gaagcataaa gttgaaacct aggattccgc ctttgatttt tgtagcttgt
    24901 acgaacaagt tacggaattg tttttcacct acaccgtaag tgaaacgaag tttttgtttt
    24961 tcagccaatt gcaaaccgta ttctgacaat ttagaacggt tgtttggtcc gtgttgtcct
    25021 ggtacgtagt tacgacgtgc caattcttta cctgtacctg taagtgaaag gccaaggcga
    25081 cgagcttgtt tccaagatgg tcctgtataa cgtgacatat gaatgtcctc ctgatataaa
    25141 taatatttcg gtggaaatag tcacttagaa agccctgatt cgtgcagatg cccttcgcct
    25201 aaacagccaa ggttacttgt cataagacac ctgttgacga gcttcatgct ttcctgctga
    25261 tatttcacac aaaatctatt ctaccatgaa tagctggatt tgtaaagggg ttttaggctt
    25321 tattttcact accagagagg ttgagaacga gggtaaaggt acttcctaga ccgtactggc
    25381 tgctgactgt gatttcccca cccaattgat gggccaattc acgcgcaatc gcaagtccta
    25441 atccatgacc acctgtcttc atgttacgcg aagtttcgac acgataaagg cgtttgaaaa
    25501 tattttccaa atcctctggg gcaataccct gcccttcatc ggtcacactg attgaaagct
    25561 ggtccttctc cagcttagcc accacttcca gcttggttcc tggagcagaa tatttaaaag
    25621 cgttatcgac cagattcacc aagatacgag aaagcttagc ataatctccc tcaatccggg
    25681 cagactctgg gattacctgc aagtggacat ctcttctctc ctgctcaatc aaaaactgaa
    25741 attcactcat gcactcaatt aagagcttgt ccagaaaaat actgtcttta ctggtagttt
    25801 ccacctgatt tctagctgtg tttagggtca aaaaattcaa ctcctcaacc agtttattga
    25861 gcctctccgt ctggcgtcca atggttgcta gataatgagc ttgctccgac tccttgataa
    25921 tcccatccaa aatcccttct accgtcgctt ggatcgaagt gataggagtc ttaatatcat
    25981 gcgacaactg ggcaatcatc aagccctttt ctcgttcgct ttcttccaag gaatcaaagc
    26041 ttacctgcaa atcatgggac atctcattaa aagtttgccc taattgctga aattctacag
    26101 gaccttgaac ctccaaattt gaaggaaaat ccttggccgc tacccgcttg gcatgctcct
    26161 tgagtttgcc caacgacgta aagactggca ataggagaaa gagactaatc ccagcaccga
    26221 caaggctggc aacgatggtc atcccaagca aaaagtaaat ctcgcctttc gcaatcagca
    26281 ttttttgaac agcccaaaaa acaaccaaaa tggttaagag ggttgaaata atatatccaa
    26341 ccaaaatata actttttagt ttcatgtttg tcctctcggt ttctctatct tatatcccaa
    26401 cccccaaact gtcttaatag tgggagtttg gtcactacta tattttgcca gctcctgtcg
    26461 aagagcatgg atatgcacat tcaaggtatt ggtgtcatcc acgtagtctt ctttccagat
    26521 cttttcatag aggtctgtct tggagaaaac tcgctctgga ttgctagcta aaatccacag
    26581 caattcaaat gatttaacag ttaaatccag catttcttct cctatttgaa cttcatgact
    26641 actatgattc atttttagat tgccaaggga aatcagctct gtttcgcccc cacgatgaag
    26701 gcggcgcaaa atattgtgga cacgcaaaac cagctcacgt gggctaaaag gcttagcaat
    26761 aaaatcatct gctcccaagc tcaggccgta aatcttgtcc tgttcactgg tcttagcagt
    26821 aataaatagg aaaggctgct ctggtgataa gtattgaacc tcactgatta aatcataacc
    26881 atccatccga ggcatcatga catctgtgat aatcaaatca atcggttttt tcttgaacag
    26941 ctctagcgct tccagtccat catgggctac caagacctga taacctgcct gaattaagta
    27001 tctctgatga atatctgtga tttctacctc gtcgtcaacg agtaaaattg tctttcccat
    27061 ctgtctctcc tttgataaaa acagtgctat actgctttaa gtataacact atttttattg
    27121 ttttacgatg attttaatct gctattgaaa gaaagtcctg attgctgatt gagttgttaa
    27181 actaatctta gtcagcccac tatccatcat ttatttcctt agctgattag ttttcttctt
    27241 ttttgttttt caaacctaga ccaccgagta aacctgcaag cgcaagccca aggaaaccaa
    27301 tacttgccat tgatgtttga gtctcaccag tatttggtag catagcttta tcctctgaca
    27361 tcatcgtatc agacatcttg ttagcagaag cagccatgtt ttcacctgcc atcgtgttgg
    27421 tagaacttgt catggtgtca gcaggcatgc tatctgtagt acctgtagca tgattgtgat
    27481 tcatcggagt cacgccagaa ccagagttag aaggtgataa tgaaccattt gctgtgtctg
    27541 atgtttcttt aacatttatc ttaatagtga cttttttagt tgctacgatg ttgtccaagt
    27601 ctggtttacc gtctttgtta ccatagacat tgactgtagc gctgtaagtt tgagtacc
//
LOCUS       DBERXF010000030        27258 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.30, whole genome shotgun sequence.
ACCESSION   DBERXF010000030 DBERXF010000000
VERSION     DBERXF010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27258
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.30"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..1086)
                     /locus_tag="ACL8JK_001408"
                     /pseudo
     CDS             complement(1..1086)
                     /locus_tag="ACL8JK_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251597.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1068..1375
                     /locus_tag="ACL8JK_001409"
                     /pseudo
     CDS             1068..1375
                     /locus_tag="ACL8JK_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1530..1853)
                     /gene="tnpB"
                     /locus_tag="ACL8JK_001410"
     CDS             complement(1530..1853)
                     /gene="tnpB"
                     /locus_tag="ACL8JK_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS1786277.1"
                     /translation="MTIHLSSLGQVYLVCGKTGMRQGIDSLAYLVKTHFELNSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPKI"
     gene            complement(1834..2019)
                     /locus_tag="ACL8JK_001411"
     CDS             complement(1834..2019)
                     /locus_tag="ACL8JK_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786278.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MIEQLLDKVLLYDNSSI"
     gene            complement(2323..3885)
                     /gene="guaA"
                     /locus_tag="ACL8JK_001412"
     CDS             complement(2323..3885)
                     /gene="guaA"
                     /locus_tag="ACL8JK_001412"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGS1786279.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKADWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4027..4725
                     /locus_tag="ACL8JK_001413"
     CDS             4027..4725
                     /locus_tag="ACL8JK_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS1786280.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKYGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4768..5664)
                     /locus_tag="ACL8JK_001414"
     CDS             complement(4768..5664)
                     /locus_tag="ACL8JK_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS1786281.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     IGMAMILFAVTLISLKDLFLEK"
     gene            complement(5673..6608)
                     /locus_tag="ACL8JK_001415"
     CDS             complement(5673..6608)
                     /locus_tag="ACL8JK_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGS1786282.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6605..7330)
                     /locus_tag="ACL8JK_001416"
     CDS             complement(6605..7330)
                     /locus_tag="ACL8JK_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HGS1786283.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7414..8049)
                     /locus_tag="ACL8JK_001417"
     CDS             complement(7414..8049)
                     /locus_tag="ACL8JK_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGS1786284.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNSLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(8051..8878)
                     /locus_tag="ACL8JK_001418"
     CDS             complement(8051..8878)
                     /locus_tag="ACL8JK_001418"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS1786285.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8900..9235)
                     /locus_tag="ACL8JK_001419"
     CDS             complement(8900..9235)
                     /locus_tag="ACL8JK_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HGS1786286.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(9236..9826)
                     /locus_tag="ACL8JK_001420"
     CDS             complement(9236..9826)
                     /locus_tag="ACL8JK_001420"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HGS1786287.1"
                     /translation="MGDFEGTINKDHYLAGYLLFNAPAEVMDAIKEAGYHVLDLAHNH
                     ILDSQIEGVISTADIIEKAGITPIGVYTHEPRDQALLVIKEVNGIKVALLAYSYGFNG
                     IEQYISQEDYNRYLSDLNEDKMKVEIERAEKEADITIIMLQMGVEYRLELTEEQKALY
                     HKMIDWGADIIFGGHPHVVEPSETVEKDGDKKLIIY"
     gene            complement(9842..9964)
                     /locus_tag="ACL8JK_001421"
     CDS             complement(9842..9964)
                     /locus_tag="ACL8JK_001421"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786288.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQGD"
     gene            10477..11088
                     /gene="def"
                     /locus_tag="ACL8JK_001422"
     CDS             10477..11088
                     /gene="def"
                     /locus_tag="ACL8JK_001422"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGS1786289.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11133..11861
                     /gene="rlmB"
                     /locus_tag="ACL8JK_001423"
     CDS             11133..11861
                     /gene="rlmB"
                     /locus_tag="ACL8JK_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGS1786290.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(11900..12811)
                     /gene="trxB"
                     /locus_tag="ACL8JK_001424"
     CDS             complement(11900..12811)
                     /gene="trxB"
                     /locus_tag="ACL8JK_001424"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGS1786291.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12877..13101)
                     /locus_tag="ACL8JK_001425"
     CDS             complement(12877..13101)
                     /locus_tag="ACL8JK_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HGS1786292.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13179..13922)
                     /locus_tag="ACL8JK_001426"
     CDS             complement(13179..13922)
                     /locus_tag="ACL8JK_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1786293.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13922..14722)
                     /locus_tag="ACL8JK_001427"
     CDS             complement(13922..14722)
                     /locus_tag="ACL8JK_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1786294.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14880..15236)
                     /locus_tag="ACL8JK_001428"
     CDS             complement(14880..15236)
                     /locus_tag="ACL8JK_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGS1786295.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15249..15761)
                     /locus_tag="ACL8JK_001429"
     CDS             complement(15249..15761)
                     /locus_tag="ACL8JK_001429"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGS1786296.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15761..16255)
                     /locus_tag="ACL8JK_001430"
     CDS             complement(15761..16255)
                     /locus_tag="ACL8JK_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGS1786297.1"
                     /translation="MEIRLAFPNEVGAIMQVIEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16390..16836
                     /locus_tag="ACL8JK_001431"
     CDS             16390..16836
                     /locus_tag="ACL8JK_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGS1786298.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16833..17480
                     /locus_tag="ACL8JK_001432"
     CDS             16833..17480
                     /locus_tag="ACL8JK_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGS1786299.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17501..18082)
                     /gene="pdxT"
                     /locus_tag="ACL8JK_001433"
     CDS             complement(17501..18082)
                     /gene="pdxT"
                     /locus_tag="ACL8JK_001433"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HGS1786300.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18083..18958)
                     /gene="pdxS"
                     /locus_tag="ACL8JK_001434"
     CDS             complement(18083..18958)
                     /gene="pdxS"
                     /locus_tag="ACL8JK_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042819 - vitamin B6 biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HGS1786301.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19110..20489)
                     /gene="nox"
                     /locus_tag="ACL8JK_001435"
     CDS             complement(19110..20489)
                     /gene="nox"
                     /locus_tag="ACL8JK_001435"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HGS1786302.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20783..21706
                     /locus_tag="ACL8JK_001436"
     CDS             20783..21706
                     /locus_tag="ACL8JK_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGS1786303.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21766..22371
                     /locus_tag="ACL8JK_001437"
     CDS             21766..22371
                     /locus_tag="ACL8JK_001437"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGS1786304.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22390..23634
                     /locus_tag="ACL8JK_001438"
     CDS             22390..23634
                     /locus_tag="ACL8JK_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGS1786305.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRHFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(23751..24008)
                     /locus_tag="ACL8JK_001439"
     CDS             complement(23751..24008)
                     /locus_tag="ACL8JK_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGS1786306.1"
                     /translation="MDPKKIARINELAKKKKTEGLTLEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24050..26086)
                     /gene="glyS"
                     /locus_tag="ACL8JK_001440"
     CDS             complement(24050..26086)
                     /gene="glyS"
                     /locus_tag="ACL8JK_001440"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGS1786307.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKGKRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGGATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26298..27215)
                     /gene="glyQ"
                     /locus_tag="ACL8JK_001441"
     CDS             complement(26298..27215)
                     /gene="glyQ"
                     /locus_tag="ACL8JK_001441"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGS1786308.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
BASE COUNT         8047 a         6127 c         4983 g         8101 t
ORIGIN      
        1 atagatattt ctcactattt agttgatgac gtttagctgt ttccaacaaa ctcataataa
       61 tagctcttgc tttagctcct tcaaaacttt gagaaaacaa ccaccctcgc ttttttaaac
      121 tgagcttagg ctaaaagagt ccagtggact cttttactcc gtcccataac caatgattta
      181 atggcgtgtt cagctagatt attggaaagg accagatgtc cgtcttttaa aatggtctta
      241 aaggtttctt catacttgag gctgtattca attgcccttc ctggttttga acctgctaaa
      301 actgactgac ggcggcacca agcaaagaag tcttccatta agggctggac gtttctgtag
      361 tcgttcatca gctggcaaag cctcccagtc tctttccaag gcaaataact ggtcacgata
      421 ggctaaacct ttagctccta aggatgattt atctgcttgc ttgggggtcg cttcaaaaaa
      481 tttccttctc acatgcgccc aacatccaac aagttcagct tcttccagtt gacgataagc
      541 ttctagcggt tcgcagttta ccaagcttag cgtcgccttg ctcctaaacc ttagactgct
      601 atcgcatagg cagaactaga ggactaaagt tctaagttac tgccgcaaca tatcacaatg
      661 catatagcca gaataatttc ctaggaattc ttgcactacc gaaccactcc gacgctgatc
      721 atggtggtac agcgtaatcc cttgtttctc agctttccca gacaaaaaag tccaatagta
      781 agtcagctga ctatcacttt ctaagacccg ataagaggtt tcatctgcat gaagaagagc
      841 ttgttctaac aacttttctc gtaaaaggtt ataaaggggc tccaaatagt attgactcgt
      901 cttgatatgc caattagaga tttccttacg tgtgattggt aaacccatcc tagcccaatc
      961 ttcttcttgg cgataattgg gtaccttcag attaaacttc tgatggatgg tgtgagcgat
     1021 aatagaagct gagccaaggc tatgcgccaa aggggcttta ggaataggag ctttcacaag
     1081 cttatccaga tgattatctt ttactcgtta tgaacaatgc tatatggcat aaatcaagta
     1141 ccttaaagat tccgactaat attggctttg catttattcc tccatacaca ccagagatga
     1201 acccattgaa caagtgtgga aagagattcg taaacgtgga tttaagaata aagcctttca
     1261 aactttggaa gatgtcatga atcaacttca agatgttata caaggactgg agaaggaggt
     1321 gataaagtcc atcgttaatc ggagatggac tagaatgctt tttgaaagca gatgagtata
     1381 aaaagaaagt cctcatttca atagaaatca cgactttctg atggatttat agtaaaatga
     1441 aataataaca ggacaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaag
     1501 caaaggtgta ctattctagt ttcaatctac tatatttttg gagtgataga aaagcctttc
     1561 atcagccaat ctacttgttc aggtgcgaga gctttgacat ccttttctgt actgggccaa
     1621 gtcagtctgc cgttctcaaa gcgtttatat aatagccaaa atccttgacc atcccagtaa
     1681 aggactttaa agcggtcttt acgtccacca caaaagagaa aaacttgacc tgagaaagaa
     1741 ttcaattcaa agtgggtttt aaccagataa gccagtgaat cgattccttg tctcataccc
     1801 gttttcccac atacgagata gacctgccct aggctagata gatgaattgt catagagcaa
     1861 caccttatcc aaaagctgtt ctatcatttc gagattgaga gattgaaaaa aacttacttc
     1921 aagcttgcca atacgaattt taagcagaat atcatttctc tttttagaat caaaacgacg
     1981 agattgtgga atctctacag gaacaatagg ttgtggcatt aaaatatcct ccaatagttt
     2041 tactttacta atagtataca ggaggagctc catgaatgat agataccttg ttatgacgcg
     2101 cttaccatat tagaaagttg gctctctaat taaattaatt ctcattatat atatcaaaaa
     2161 accgcagctt gaaaactacg gtctaatttt ttgtccaaat gtaaaccact tggaactatt
     2221 attcaattta ttctttttag caaatgttcc cgttttaatc ccagttacag tttttaatcc
     2281 tctgtaaccg ttgattttac aaagctttta atttttttgc gattattccc actcaactgt
     2341 tgcaggtggt ttacttgtaa tatcgtagac gatacggtta acatgatcca cttcatttac
     2401 gatacgtact gagatttttt gaagtacttc ccatggaatt ttggcaaaat cagcagtcat
     2461 accatcgata gaagtgatag cacggattgc aatcgtgtag tcatacgtac gaccgtcacc
     2521 cataacaccg actgagcgaa cgcctgtgtt aacagtgaag tattgccaaa tatcgcggtc
     2581 aagtccagct ttagcgattt cttcacgaag aatagcgtct gattcacgaa cggtttcaag
     2641 tttctcttca gtgatttcac ccatgacacg gatagcaagt cctggtcctg ggaatggttg
     2701 gcgccatacg atgtggtctg gcataccaag ctctgtacca agagcacgaa cttcatcctt
     2761 gtaaagagta ttgagtggtt caatcagttc aaactgcata tcttctggaa gaccacccac
     2821 gttgtggtgt gacttgatag tttgagctgt atccgtacca gactcgataa catctgtata
     2881 taaagtacct tgagcaagga atttcacatc tttgagcttg cttgcttcgt catcgaatac
     2941 atagacaaac tcgttaccga tgattttacg tttttgttca ggatcagaaa cgccagcaag
     3001 tttgtcaagg aaacgtttag cagcgtctgc tttgacgata ttcaaaccaa acttaccacc
     3061 gagcatgtcc ataacttgat cagcttcgcc tttacgaaga agaccgtggt ctacgaagat
     3121 acagatcaat tgatcgccaa tcgctttttg gagaagaacc ccaacgacag atgagtcaac
     3181 accacctgat agaccaagaa ggacacgttt atcaccgacg gtttcacgaa tttttttgat
     3241 ctgcatatca atgaaattat ccattgacca gtcagcttta gccttacaaa tgttaagggc
     3301 aaagttacga aggatatcat ttccgtatac agaatgacga acttctgggt ggaattggat
     3361 accgtaaatg tgtttatctg ggttttcgat ggctgcgtat gggcagtcag ctgatgtacc
     3421 tgtacgaaca aagtcagcag gaatctcagt aaccgcatca ccatggctca tcaaaacagt
     3481 ctgttcatca ggtgttgatt caaaaagcgc tgatggtgtg tgagttaggg ttgattgacc
     3541 gtattcacga tttccagcat cacctgcagg aacaactttt cctccaagtt tatgggtcaa
     3601 taactgcata ccataacaga ttcccaaaat tggaattcct agttcgaaga tttctgggtc
     3661 aatgtcaaat gaaccatctt catatacaga atttggacca cctgatagaa taattcctac
     3721 aggattgact tcacgaactt cagcagctga aattttatgg ctttttagtt ctgaaaaaac
     3781 accaatctca cggatacggc gtgaaatcag ctggttgtac tggctaccat agtccaatac
     3841 gatgattttt tctacatctt gcaaatcagt tgaaatgttg ctcatctttt tcctttctca
     3901 aaagaaatat cttttctcaa tattctatca caaataaggg cgaattacca actaaacaag
     3961 gcgaagtttg actttttcta gtttattggg gtacaataga gaaaagatag aaatgaagtg
     4021 aaaaatatgc tacctgctta tatgaaaatc catgatcaga taaaaaagga tattgacgag
     4081 caccgttggg ctattggtga gaggcttccc agtgaaagag atttagctga gcagtttgcg
     4141 gtcagtcgca tgaccctccg ccaagccgta tctctattag tcgaagaagg cgtcttagag
     4201 cgccgtgtag gaagcggcac ctttgtttcc agtactcgag tacaagaaaa gatgcgaggg
     4261 acaaccagtt ttactgaaat tgtcaaatcc caaggtaaag ttccctctag ccagctcatt
     4321 tcctacaaaa aaaccattcc caatgagcaa gaagttgcca agctaggaat ttttccaacg
     4381 gacaatatta tccgaatgga gcgggtccgc tatgccgacc aagttcccct agtttatgaa
     4441 gttgcttcta ttcctgaaaa attcattaag gactttaaaa aagaagaaat caccagtcat
     4501 ttcttccaaa ccttgcaaaa atatggctat cgtatcggca aatctcaaca gaccatctat
     4561 gctcgccttg ctaaagaaaa gattgcccac tatttggaag ttgaaaaagg acatgctatt
     4621 cttggattga cacaggtttc ctacctagaa gatggtactg cttttgaata cgtaaaaagt
     4681 caatatgtag gcgaacgctt tgaattttat cttgaaaata attagattac cacgcaaaaa
     4741 ctctctgtca cagacaaaga gtctttttta tttttctaag aataaatctt tcaaagaaat
     4801 caaagttaca gcaaacaata tcattgccat accaataaaa tcaatgggat aaaattgttc
     4861 attcattatt aagaaggcaa agaaaaccgc cgatattggc tcaattgaag ccaacaagct
     4921 tgacttgacc ggtcctatca gactggctcc tttaaggaaa gctgtatagg caaagacagt
     4981 cccgataagg ataatgcctg caaacgcaag gagaaaatca agactagtcg ggatatcggc
     5041 ctgtagaacc cctgtaaaag gaagggcgac caaacctgct atgaccattc ccacaccaat
     5101 gaccaagctg ctcccccact ttttaatcaa ggctatgggt aaaatgatat acagagcata
     5161 agtcaaggca gaaaagagac cccagaacag gccagcaggt gtcatggata actggtccaa
     5221 ctgcccatgt gttgcgatca ggaaggttcc tccgatggcg aatatgatgg aaactatctc
     5281 tcccagtgtc ggtgccaccc tatccttgat acagctataa attaaaattc cgacaggaca
     5341 aacatactga agcaccgtcg ctgttcccgc attggtctcc tgaatagcag acagataggc
     5401 gaattggttg agaaaaagac caatcagagc aaaaataaga agagacagca aactctttct
     5461 atcctttaaa aagaccagta ttttatcctt tgcagtagca taagccaaga gcatgagaat
     5521 tccaccagcg attaaaagac gcaagttggt taagaccaga gccgaaattc cgtgtgccat
     5581 caggtattgg ccactcgttc ctgacaaccc ccaagcaata ccagccacaa ctgttagtaa
     5641 agtccctttt aaactatttg acatgtctct ccttactctt ctttgcgaat caagttcatc
     5701 acttgattgc ggtctaatat ccattgagct ctctcgtcct tttcataggt acgattcgat
     5761 aggaaaatag tggcttcttg cttctgacga ttccacatga taaaggtacc tgtatagccc
     5821 gtatggtcta gccaatctcc ttccaaattc catgctaaag aacgttcctt gtcatccaaa
     5881 ggagaaaaat tttgatttaa gtctcttgca aaatcatctg ctaaatagtg ttctaaaaag
     5941 atttgtaaat cctttatagt cgaaaataaa ccagcactcc cagcatgtct acccaggaga
     6001 cgagccttgg gatcatgcac tatgcctgcc tctacacctc taactgttgg aacagcaagc
     6061 tcaactggcc caaacttggt ttccgtcatt ccccaaggtt tccagacttg atcctttaaa
     6121 atcacatcca aatcttgatt aaaaattctt tccaaaataa agcccaacag caaaaaatgg
     6181 acatccgaat aaagaaaggc tggctgactt cgtctgttga gatgaaacat cgcttccttt
     6241 aattcagggg ctgttaaaag atcacgatta ggaataaaag gatcaaggtc tgttgcatga
     6301 gtcaagagct ggcgaatagt gatgtctgga taatcactct caggtaaaaa atctattacc
     6361 agtctatcaa tatctaattg acctatttcc cacaagaagg tacaaactgt gccaacccca
     6421 acaaccttgc tgacactagc taggtcataa actagtcctg cctcagtctg caagccatgc
     6481 tctgggtcac tctggcctaa atagaactct gtccattgat tgtccttaaa atacgcaaaa
     6541 gaggctccgg gataaattcc tgcctcgatt tgttcttcta tttttttaat aatcttggtc
     6601 cacttcatac ttcttcaaac cacaattcaa cattatttct atctttacca aggaagaatt
     6661 tttcagactt aggaataaaa tattcagtag actcaaactt ctggcgaaga cttgctatgt
     6721 ctaattcatt gaccaagaac ttgagcatag ataagtccca ggtaaccgta ttgtccacag
     6781 tcaaatcctg cccctgagct ggaataaaat caagggatgc cccaatttca gatgattcca
     6841 agaaactttc gatatcagtt gggagatgta attccataga aatctcaaat ttacttaaag
     6901 aaattgatgc caaatctgtt tgaaattcag gcttttctcc tacttctact agacttgctc
     6961 tgtcatcttc cgcatgaatc aaaatcaaat catcttctgg tgagaaaatt tcaaaagcgt
     7021 agccattttg acctttatat aatcgatgaa tcgaatctgt tttagataag attccttcaa
     7081 tttctaaggg attttccacc ttgacaatca atctagctag tttttttctt ccctctacct
     7141 tacgagtacg catactggga gcttcttcta aaaccagctt ttcaagaccc gtttggtcac
     7201 ctagtgacag aaaggccgat tcttctaaca aggccttcat tccaagggtt tcaatataaa
     7261 atgtttcatt taattttcta ttattagctt ttaaagtagg aataatccgt acaatctgat
     7321 ttacattcat aaattcctcc gtcacttttt attttaaagg attttagaat tttttacaag
     7381 atattatgct caaatttaac attatttagc tatttagtaa agatagtctt tcaaggcttt
     7441 tgacaaagcc tgataaccag caatactgag gtgcagtcca tcagttgtat attctttttt
     7501 gagttggcct gcttggtctg tcaaacaatc aaatactggc acaaattcca cctgcatata
     7561 ggcagatgca agctcttgat aggcttgatt ccaattctga attttttcat tcgagcggat
     7621 atagactgcc tgctggtact tctctccctc attgacaggc aaaatggaaa gcaatttaat
     7681 ctctgtcaat ggataatcgc gagcaacgga ttgaatgata gcttcgagac tattgagagc
     7741 ctcattcaca ggaacatcct ttccgatatc atttgtccca atcagaagaa aaattttatc
     7801 tactgctcca ccatatagat gagcatcaag gttctctagt aacagtcctg tctgatagcc
     7861 acgaattcct cgattgacaa tcgtctttga agtcccaaat agctcctgta gaggataata
     7921 ctcgacaatg gaatccccaa taaaaagaat gtttggttct acaacagaaa tgtgatttag
     7981 gtgacgatat ttggtttgaa ttttttcttg ttcctttagg agccaatttt ctaataactg
     8041 tactgccact tcattctcct ttttctaacc agttttccaa gacttgataa actcctcctt
     8101 ggctgttggc tggtgctaga gcagtcgcca cagctttggc tttctcatca gcattttcca
     8161 tcgcataggc aattccagcc atttcaagca tttcaacatc attttcacta tcaccaaaag
     8221 ccatgatttc ttgggatttc aagtcccagc gcttgagtaa ttcctccaag ccccatgctt
     8281 tatgaatccc agcttggagg atatcaatgc aaccatagcc actggataca gctcggacac
     8341 ggccatcaaa gagagcattg atttcttcca aaaccgaact caaacgttcc tcaccaacaa
     8401 ccatgctcat cttgagcaca ccaccaaaga ggtcagatgt taattcatcc acaaattgca
     8461 tccgttggta gaatttttca atcatttctg gagtcataaa actttcaaga tctgtaaaaa
     8521 tcgtaccttc cttgacaaaa tcacccttca tccccgttac aacaaactgg tcctgacacg
     8581 ctcgaccctt gaaatgagcc aaagccttgt tgacaatggc gtcatcccat gtctgagcct
     8641 gaatcaattc attgttttca aaaatacgag cgccattagc aacaaccaga accactcgat
     8701 ccaccaaggg actcagtagt tgtctcatgc ggtgaatttc attgcccgtc gcaatgacaa
     8761 aacgaatgcc cctttgatcc aactgatcta aaatcttttc caatcgtggg agatcaagct
     8821 gacctctagc atccagcaag gtcccatcca tatctgtcgc aattacctta atcatcattt
     8881 actttcctct ggattcaagc taataccact tcaatcccac atgttcattc atttctttat
     8941 aggctgtatc aattcgttcc ttagtcgctt catctaactg gtcacgatga ctgccatcct
     9001 ctataaaatc ttccaaaata taagtttggt aatgatacaa gggatatcct tctggtgaaa
     9061 aggttccctt tggtgttcga ttgacccaag taggatgagc tttagctgtt ccgatagttg
     9121 tttttccatc cttcttcttg atggtgacat ccatgagaac accacgttca gtccacttag
     9181 cattctcttc atctcccata gattcaatcc gttgattgga aatgaagttc cccatttaat
     9241 agataatgag tttcttatct ccatcttttt caaccgtttc agatggttca acaacgtgag
     9301 gatgccctcc aaagataata tccgctcccc aatcgatcat cttgtgataa agagcttttt
     9361 gttcttcagt tagttccaat cgatactcaa cacccatctg aagcatgata atggtgatat
     9421 ctgcttcctt ctctgcccgt tcaatttcaa ccttcatctt atcttcgttt aaatctgaaa
     9481 gataacgatt atagtcttcc tgagaaatat actgctcaat tccattgaaa ccataggaat
     9541 aggctaacaa tgcaaccttg ataccattca cttccttaat gaccagcaga gcctgatcac
     9601 gtggttcgtg cgtataaact ccgattggag tgattccagc tttctcaata atatcggccg
     9661 ttgaaataac tccctcaatt tgcgaatcca aaatatgatt atgagctaaa tccagcacat
     9721 gataacctgc ctccttaata gcatccataa cttcagcagg agcattaaag agaagataac
     9781 ccgctaaata atgatcctta ttaatggttc cttcaaaatc accaatagct aaatctgctg
     9841 cttagtcccc ttgcttgagc caaggagtca catactcaaa attttcatga aagtcatagg
     9901 taccgtcttc ttttttagct gaaaagaaaa gtccatcgtg gtagagcaaa tccccgtggg
     9961 ccataattct ggcagttttt tcctcttcct actcctgaga cttttgctta gtcccctctt
    10021 gagaaatagt atctcgtttt tgactagtca agggattcct tggaagcttt caaacaacaa
    10081 gaccaagccc attgataaat caactgctag caagagtatc gccacaaatc ccttattgct
    10141 ccacttgcga taactcctaa aaagtttacc aagcccttca taaaacgaaa agctaaacca
    10201 ccctgatttc gattttgtct tctttgtatc ttcattctcc ctactttctt atgcaagcct
    10261 tttcttttta ttatatcaca gataagtatt tctttcacaa ttgaattgaa cttcccatct
    10321 attttctata aatcctaaat gccataatgc tttcaattct tgtcattttg tgatatcatg
    10381 tagaggaaat gaactaatcc acagtggctt attccaagta taccacttgg gctttggcag
    10441 tagctaactg cactaaacat aatataagga gagaaaatgt ctgcaataga acgtattaca
    10501 aaagctgctc acttaattga tatgaacgat attatccgtg aagggaatcc tactctacgc
    10561 gcgattgctg aggaagtcac tttcccccta tctgaccagg aaatcatcct aggcgaaaag
    10621 atgatgcaat tccttaaaca ttcccaagat cctgtcatgg ctgaaaaaat gggactccgc
    10681 ggtggtgttg gactggctgc tccccagtta gatatctcaa aacgcattat cgctgttttg
    10741 gtacctaata ttgttgaaga aggcgaaact ccacaggaag cctacgattt ggaagccatt
    10801 atgtacaatc caaaaatcgt ctctcactct gttcaagatg ctgctcttgg cgaaggagaa
    10861 ggttgcctgt ctgttgaccg taacgtgcct ggctatgttg ttcgccatgc ccgcgttact
    10921 gttgactact ttgacaaaga tggagaaaaa caccgtatca aactcaaagg ctacaactcc
    10981 attgttgttc agcatgaaat tgaccacatt aacggtatca tgttttacga tcgcatcaat
    11041 gaaaaagacc catttgcagt taaagatggt ttactgattc ttgaataaag aaaatcccgt
    11101 tgcaagacgg ggttttgtgt tataatagag gcatgaaaac aaatgatatt gtctatggtg
    11161 tccacgccgt taccgaagct ctccttgcaa atacaggaaa caaactctac ctccaagaag
    11221 atctccgagg taagaatgtt gagaaagtca aggaactagc tacagaaaag aaggtgtcca
    11281 tttcttggac atcaaaaaaa tctctctctg agatgactga aggtgctgtt catcaaggtt
    11341 ttgttctacg agtgtctgaa tttgcctata gcgagctaga ttacatcctt gcaaaaacac
    11401 gccaagaaga aaatccactt ctattgattc tagatggtct aaccgatccc cataatctgg
    11461 gttctatctt gcgaacagcc gatgcgacca atgtttcagg tgtcatcatt cccaagcacc
    11521 gtgctgtcgg agtaactcct gtcgttgcca aaacagccac aggtgctatt gaacacgttc
    11581 caattgcccg agtgacaaac ctcagtcaaa ccttagataa actcaaggat gaaggcttct
    11641 ggacctttgg aacggatatg aacggtactc cttgccacaa gtggaataca aaagggaaaa
    11701 tcgccctcat cattggaaat gaaggaaaag gtatctctag caacatcaaa aaacaagtcg
    11761 atgagatgat taccattccg atgaatggac atgttcaaag ccttaatgcc agtgttgctg
    11821 cggccattct catgtacgaa gttttccgaa atagactata aaaaagtttc cagtcatctg
    11881 attggaaact tttttatgat taactatgtt ctgtgataaa cttgtaggct tcttgaccag
    11941 cgatagctcc atctccaact gctgttgtta cttggcgaag gtctttcaag cgaacatctc
    12001 caactgcaaa gataccgtcg actgcagtct tcatgtggct atctgtcaca atccagcctg
    12061 cctgatcttg gatattcaat tctttaacaa aatcgctaag agggtccaaa ccaacataga
    12121 taaagacacc accgaaggct tgttctgtca cttgacctgt tttcacattt tcaaatacga
    12181 ctgattctac tcggttttca cccttgattt cccttactac agaatcccag ataaagctga
    12241 ttttttcatt cgcaaaggcg cgatcttgta aaaccttttg ggcacgaagt tggtcacgac
    12301 ggtgaacaat ggtaacagtc ttagcaaaac gagtcaagaa gagggcttct tcaacagctg
    12361 aatctccacc accaactacc aataaatctt ggtcacggaa gaaagcacca tcacacacag
    12421 cacagtaaga aacaccacga ctgttcagtt cttcttctcc aggcactccc aaaggacggt
    12481 gtttagaacc agttgctacg ataactgtac gtgtttcata tgtttggtca tcagtcatca
    12541 ctttcttaaa atcaccatgg tcttcgacat tttcaacata accataaatg tgctcaacac
    12601 caagattttc aagtggttca aacatctttt cagccaattc aggtccacta atattagcgt
    12661 atcctgggta attttcgata tcagatgtat tattcatctg accacctggc agaccacctt
    12721 caatcaaagc tacttttaga ttgcttcgag cagcatacaa ggccgcagtc atccctgcag
    12781 gtccagcacc gataataata gtatcgtaca tatagattcc ttctttcttg ttgtaactat
    12841 ctttattcta actctttctt gtcaatcacg caaggattat gccttgaaaa caagaattaa
    12901 actcataacc gcaaaggata atactgggac aaccaagact ccaatcataa tcatatcata
    12961 gagatgggct tggcgagcct tggctgtctt atcaactccc gacatggctc tcagaccaat
    13021 ccaaatccct aaaaaaatca gaacaaggat ggtggtcaat atcaaactct cgaaatataa
    13081 agaaaatagt tgcagtagca tgatttctct catttctatc ttttttaaag agtaaactca
    13141 gctagtccaa ctaactgagt tttcctttat ctattatatc aaatataagt ccgtttgtaa
    13201 ctagcgaaga attcttttgt ccgctcttct ttaggggtgt ggataatctc atccggagtt
    13261 ccagactcga tgattttccc cttatctaag aagagaatct tatccgcaac ttgggctaca
    13321 aaggacatgt catgactgac caaaatcatg gtctgacctg acttagcagc atctgcaata
    13381 gacttttcta cttcaccgac caattctggg tcaagggctg aagttggttc gtctaagagc
    13441 aaaacatctg gtttcatagc aagcgcacgc gctagggcaa cccgttgctt ctgtccacct
    13501 gataaatggc gaggataatg gttttcacgg tccgaaagcc caaccttagc caactcttcc
    13561 ttggcaatct tagtcgcttc ttggtcagat aatttcttga caacaaccaa gccttctttc
    13621 acattatcaa gtgctgttcg gcgttcaaac aaattaaact gttggaaaac catagacaac
    13681 ttacggcgta gggcaaggat ttcttcttga gtgattttag aaaaatcaac tgaaaaacca
    13741 tcaatctgaa tagagccact gtcaggtgtt tcaagataat tgagactgcg aagaaaggtt
    13801 gattttccag ctcctgaaga accaatcaag gctacaactt cccctttttg aatatccaag
    13861 tccagatgat ccaagacagt ctgtcctgaa aaggatttgc ttaaattcga aatcttaatc
    13921 attaacgaag gtctcctttc acatctgttt gcactgtatc aggtgcagaa atagccattt
    13981 ttctctcgat gaaacgaccg aggctttcaa ttccgatatt gactacccaa taaacaaggg
    14041 caacggagat gaagcgttca aaatagcgat aatcagctcc acctagaatc tgagcttggg
    14101 caaagacttc cacaacaccc gcactaaaag ctagagatgt tcccttggtc aaaccgatga
    14161 gggaattaat caaggttgga gtagctacca ccgctgcatt aggaataatc actcgtcgat
    14221 aaacttgcgc tcgggtcata cccagactgc gtgccgcctc aatctcacca ggattaactg
    14281 agagaatggc tgcacgaatg gtttcactag cataagctgc ctcattaaag gcaaaagcga
    14341 caatcgcaaa agctgcagct ggaatcgcat tgatattgag accagttccc cattgctgat
    14401 tgagggcttt caaagccaaa gggattccgt agtaggtcaa catgagttgc accaaaatcg
    14461 gtgtcccttt taagaaacta acaaagaagg cctgcaaggg atataaaatc ttgacacgat
    14521 tgatcttcac aatggcaaaa agaagcgcca aaaccaagcc aaaaagggca ccaccaattg
    14581 tcaacataat tgttgttgga agttgttgga caattctagg gattccatca aagaccgaac
    14641 gtaggctaaa cagcttgcca tccggaatca attgcatcaa gttttggtac caatctgatg
    14701 ctaaaatcgt tgtaacattc ataaaaacat cctcttctga taatgattca ttctaccatg
    14761 cttctgccgt caatgaaatt atttgctacg gtcagataca gactttgtct acctactagt
    14821 ttatcatact ttgaaacagg gaagttatat attttatcta tcaaagagat agataaaaac
    14881 tatttcagtc ccagttcttc ataagatttt cgataaccga tttgcttaac agttccattt
    14941 tctactaaaa tgggccgttt taacaacata ccgtcacttg ctagcaactc agccgcttct
    15001 tggtttgaca aacttcctac cttatctttt agccctaatt cacggtattt gataccactg
    15061 gtgttgaaaa attgcttcaa ttcaaatcct gaggtttcta gccaattcaa aatgacttct
    15121 tggctaggtg tttcttccac gatatggacg gctttatagt ccacacctaa ttgatttaat
    15181 tcttgttttg cttttttaca agttgaacat ttggggtatt cgataaattc taacatgtgc
    15241 ttctccttct atttgtttat atctttaaaa tctacgcctt catgctccaa gagccaagct
    15301 ttcttttcca ctcctgcagc atagcctgtc agacgcttgc ctgctcccaa cacacgatga
    15361 caaggtacta ggatagacca aggattgcgt cccactgctc caccaattgc ttgagcagaa
    15421 gccacttgca ggtcttgagc aatttgtcca taggtcactg tctgaccata aggaatgccc
    15481 tgtaaatagt cccaaactct cttttcaaaa ttcgttccga ttggcgccaa gagcaagttg
    15541 gataaatcct gaggcttgcc tttaaagtaa tcatctaagc aagcaataac tgggtctaaa
    15601 ataggatgac taacaacttc ttctatcgtt tcatctccta gtcccctctc aaaatgcttc
    15661 tgctcctgaa cccaaattcc atacaaataa tggtcatcag ctacaagtga tagaatacca
    15721 attggtgagg agtagaggat ttttacatac ttcttttgca ttatttcttt aatttttgat
    15781 aggccaagcg ttcgccatct actggcacct taccaacttg tttaaaacca agtttttcaa
    15841 aaatatgttg cataaccttg ttttcagcat gcgtatctga gcgaaaatca agataatcaa
    15901 aaccttcaat caagccctct aagaaggttt gagcaactcc ttttccctgc acatctgctg
    15961 ccacagcaat acggtgaaag actagatact ctgactctcc agcttgccag tttccctcat
    16021 aaatagcttc ataggcctcc tctggactct tggtcacagc agcataggct agcagttctc
    16081 cctcttccaa ggctacgtag gcttgccctg agatgatatc atcgataata acatctgcat
    16141 ttggatagcc attttgccac tggtcactac cagcatctgc taaacatttt ttggcatcct
    16201 ctatcacctg catgatggca cctacttcat ttggaaaagc taaacgaatt tccatctttt
    16261 ttcctcattt ctgactagtt tctcccatca tagcataatt taagtctttc tacaagcagt
    16321 taaaacttga ctttgtattt ttgttatttt ataatctagt tatcaaaact atataaaaag
    16381 gagttgaaaa tgaaaactac cttttcctac ccaaaatggg cagaaattcc aaacattaac
    16441 ctctatctgg accaggtttt gctctatgtc aatcaggtct gcgcccctat ctctcctaat
    16501 aaagacaaag gcctaacagc atctatggtc aacaattatg tgaaaaatgg ttacctgaca
    16561 aagcctgaca aaaaaaaata ccaacgccaa cagattgccc gtttgattgc tatcacaacc
    16621 ctcaagtctg tattttctat tcaagaaata gcccagacac ttaatactct acaaactcaa
    16681 gcaagttcag accaactcta cgatgctttt gtggactaca tgaaccaagg aattgaccca
    16741 gctaacccta ttatccaaac cagctgccaa accgttaaac tctatcatca aactctagac
    16801 ttaatcgatc atactcaaga ggaggtaatc caatgaacac tagtcttaaa ctcagcaaac
    16861 aactcagttt tggagaggag attgctaata gcgtgaccca tgctgtgggt gcagtcatca
    16921 tgcttatctt gctgcctatt tcatccatct atagttatga agcacacgga tttttatcct
    16981 ctatcggcgt ttccattttc gtcatcagtc tctttctcat gttcctatca tccaccattt
    17041 atcactctat ggcctatggt tcgacccaca aatatgtttt gcgaatcatt gaccattcta
    17101 tgatttacgt tgccattgcc ggctcataca cgcccgttgt cttgaccttg atgaataact
    17161 ggtttggcta tctgattatt gtcatccaat ggggaacgac catctttggt attctctata
    17221 aaatctttgc taaaaaggtc aatgagaaat ttagccttgc tctttacctg attatgggct
    17281 ggttggttct ggctatcatt cctgccatta tcagtcaaac gacacccgtt ttctggagtc
    17341 tcatggtaac tggcggactc tgttatacag ttggagctgg attttatgcc aagaaaaaac
    17401 cttatttcca catgatttgg catctcttta tcctagctgc gtccgcactc caatacatcg
    17461 ctattgttta ttacatgtaa aaaagttgag aagttcaatc tcaacttttt tctttacaca
    17521 tattgataaa gtactggtgc aagcgcacat catcagtcaa ttctggatga aaagaactta
    17581 ccaacatatt tttttcttgg gctgcaacaa tttgattgtt cactgttgct agaatttcta
    17641 caccctcacc aacactactg ataatcggac cacggataaa ggtcattgga atcttgccaa
    17701 ctcccttaca ttctgcttcc gtgtagaaac ttcctaattg gcgcccataa gcattacgct
    17761 cgaccaccat atccatagtt cctagatgac tctctttctg agaagtgatt tccttagcca
    17821 gcaaaattaa gcccgcacag gtcccaaaca ctggtaagcc agatagaatg gcttctcgga
    17881 tgggaagtag catgttctgg tcacgtaaga gcttgcccat ggttgtagac tcaccaccag
    17941 gcaaaatcaa acccgacaag tcactctgat cttgctgaaa atcatctaga tttctgagtt
    18001 ctacactctc gacacctaat tgatctagca cttttgcatg ttctgcaaag gccccttgca
    18061 aggccaatat tccgattttc atctattttc ctcgttcagc catgagaatt tggatttcat
    18121 tttcattaat accaaccatg gcttctccta aatcttcaga gatttgagct aggatttgag
    18181 gattacggaa gttagtcaca gccttaacaa tggcactcgc tcgtttaaca ggatctcctg
    18241 acttgaaaat acctgaaccg acaaagaccc cctctgcccc taattgcatc attaacgcag
    18301 catctgctgg cgttgcaaca cctccagcag cgaaatttac aactggcaat tttccatgtt
    18361 catgaacata ttggaccaat tctacaggga cttgcaaatc cttggcagca acataaagct
    18421 cgtcctcacg taagttttga atgcggcgaa tttcctgatt catcatacgc atatgacgaa
    18481 cagcttggac gatatcccct gtccctggtt ctcctttggt acgaatcatg gaagcacctt
    18541 cagcgatacg acgcaaggct tcacccaaat ccttagcacc acagacaaaa ggaacttgga
    18601 attctttctt gtccacatgg aaacggtcat cagctggaga tagaacttca ctctcgtcga
    18661 tataatcaat ttcaatagcc tctaaaatct gagcttcaac aaaatgcccg attctgacct
    18721 tagccattac tggaatacta accgcttctt ggatttcctt aatcatcttt gggtcgctca
    18781 tgcgggaaac tcctccagct gcacgaatat cagccggaat tcgttccaag gccatcacag
    18841 ctgccgcacc agcagcttct gcgatacgag cctgttcagg attctgcaca tccataataa
    18901 caccaccctt gagcatctgt gccaagtttt tatttagttc ataacgattt tcagtcattt
    18961 gttttatcct catcatttgt attggtagct accttttcat tttaagtcag aacagaatga
    19021 agcacaagat aaaaaaacta taattgtatg gggacagatt ggctaaaaac tatctgacct
    19081 taacttaagg ccagatagct cattcatttc tatttttcag ccgtaagggc agccattgtg
    19141 atgtagttgt atggtttgtt gaagtgtggc aagaagaaga ggtctgtcaa tgccaattta
    19201 tcaattgtca catgctcttg gatagcaagt gagaacatgt ggattcccat gctaattgca
    19261 atatcatgtg aaaccatttg ggcaccaaga atttcacggc tatctttgtc aaagacaatc
    19321 ttaattgcta cttcatggtt gtcatgtttc atgaattctg gtttttgaag atcgttaaag
    19381 cctgtttcag ttgcgttgta accagcagct ttcgcttttt caagagtcaa accagttgaa
    19441 accatgtgaa gaccgtagat tgagatacca tttgaacctt gaacaccgat tccttccaat
    19501 tcatgtccac aagcattgta ggcaccaacg ataccagtgc gaacagcatt tgaagcaaga
    19561 gcgatatagc ttgtatcttt acgagcattg tcataaacag tcgcacagtc accaacagcg
    19621 taaacgcctg ggatagatgt ttcttgtttc ttgtctacaa ggaaggcacc gttgcggaag
    19681 agttcgatct taccatctgc aagggctgtg tttggacgga aaccaactgc aaggataacc
    19741 atatccacgt caaagctttc tttgtcagta atcaagcgtt caactttacc gtcaccttcg
    19801 attgctttaa cagtttgacc tagagccaag cggatgttgt gatcttccaa gttcttcgcc
    19861 atcatttgtg tgaagtcttt gtcatagtaa ccgttcaaga cagtatcaac gatatcaaca
    19921 aggacaactt cttttccaag acgttcaaag gcttcagcaa gttcaacacc gatgtaacca
    19981 ccaccaacaa cggcgatacg gtcgaggtgt tggctcttgt cagaaagttt attgataact
    20041 tcttcagcat tttggtacaa tttcacgaat tgtacgtttt caagagttgc tttaaattcg
    20101 cggtttcctt taacaatttc aacaccttcg attggtggca agattggtgt agaacctgta
    20161 gcgaaaatca atttttcgta tgattctttg tgctcttttc cttcaacttc cgctgtaact
    20221 actttgttat catagtcgat tgaaagaaca ggtgagttca tgtaaacttt agcaccttta
    20281 gcttccaatt tttctttatc agaatagaac aagccttcag caccgtcaat ttgttcacca
    20341 atccaaagag ccattccaca tcctaggaaa gagatgttag agttttggtc aaatacaaca
    20401 atttcgttct catttccaaa attatccaac atggtattga tacatgctgt accagcgtgg
    20461 ttagcaccga ctacaacgat tttactcata aaaatttcct gccttcattc taaatttacc
    20521 ttactagtat accatttacc gttagcgttt acaagggggg tactattatt tcagcatttt
    20581 ttatcaaaaa taattcccca tttatcctgt tttcaagcct catgaatttt atgagcatat
    20641 ttcttgactt tttccaaatt ttgtttgtga aaattctaac tttatggtat tataataaca
    20701 tgaaaatgaa atgtaagggc ttcaatttag atgattattt gatattacaa cttattttct
    20761 ataagagaaa ggagttggta gcttgactct tcgttcacat tctgaacggc taatggggac
    20821 tactatcact atttcattag tggatgagca agccgatatc tttctccaaa aatcctttga
    20881 cttgctcaaa gaacttgaat accgcttcaa cgccaatagt caagaatctg agttgatgga
    20941 aatcaattat caagcaggaa tagcccccgt cacggttcat ccagacctgt ttgagctgat
    21001 ttcacttggg ttagagcata gcctagcgct ctctagccac ctcaatatca gcattggtcc
    21061 cttaattcaa acctggcgta tcggtttttc agatgccaag gtcgcccagc ctcaagaaat
    21121 tgaatcggtg ctgcctctaa tcaatcctca tggtatcgag ttagattctt ctacttctac
    21181 tgtgttttta aaacagaaag gaatgaagat tgatctaggt tgtttagcca aaggatacag
    21241 tgcggataag gttgcccaat ttcttaggaa agagggggtg acttctgcct tgatcaatct
    21301 gggagggaat atcctgacca ttggaaaaaa tcaggcaaga ggggataacc catggcaaat
    21361 cgggattcaa gacccagcca atcctagggg aaatcattta atgaccatcc ctgttgtcaa
    21421 taaatctgtc gtgacttcag gcatttatga acgtcacctg accgtcgatg gacaagatta
    21481 ccatcacatt tttgacagtc aaacaggata tcctgttgaa acggaactag cgagtctaac
    21541 aatcatctct gataaatcag tcgatggcga aatctggacg actcgactct ttggagaaag
    21601 acctgcttct atcctctggc aagtcgaaag tttggagggc atcgaagtca tcctcatcga
    21661 taaagaaggc cacctaagct gttcttcagg aattcctact ctatagagac aactgtttca
    21721 atggaatttt aaaattgtat tatgtaaaaa gagaaaggaa atctcatgtt aaaacttatt
    21781 gctattgttg gaacaaattc aaaacgttct acaaaccgtc aattgcttca atacatgcaa
    21841 aaacactttg ctgacaaagc tgaaattgag cttgttgaaa tcaaggccat tcctgtcttc
    21901 aacaaaccag ctgacaagca agtacctgct gaaatattgg aaattgctgc taaaatcgaa
    21961 gaggcagatg gcgttattat cggtactcct gagtatgatc actctattcc agctgttttg
    22021 atgagcgctc ttgcttggtt gtcttatggt atttacccac ttttgaacaa accaatcatg
    22081 attacaggtg cttcttacgg tacgcttggt tcatctcgtg cccaattgca acttcgtcaa
    22141 atcttgaatg ctcctgaaat caaggcaaat gttcttccag atgaattctt gctctcacac
    22201 tctcttcaag catttaaccc aagtggcgac ttggttgacc ttgatgttat caagaaattg
    22261 gatgccatct ttgatgactt ccgtatcttt gtaaaaatca cagaaaaatt acgtaatgca
    22321 caagaattac ttcgcaaaga tgctgaagac tttgactggg aaaatttgta agataggaga
    22381 ccaaaaagaa tgaaatttgt tggacttgtt ggatcaaact acgatcaatc atataaccgt
    22441 aagctcttgg aatttatccg tcgccacttc aaactcaaat ttgaattaga agttcttgaa
    22501 attgacgaag ttccaatgtt taaccaagat gaaaaatggg atgaaagttt ccaattacgt
    22561 tatttatata acaaaattac tcgtgcagat ggtgttatca ttgctactcc tgagcataac
    22621 cacactatct cagcttcact caaatctgta cttgaatggc tttcatacga agttcatcca
    22681 tttgaaaaca agcctgttat gattgtgggt gcatcatact atgaccaagg aacatcacgt
    22741 gctcaagttc accttcgtaa aatccttgat gctccaggtg ttaatgccta cacgcttcca
    22801 ggtaacgaat tccttcttgg taaagctaag gaagcttttg ataacaacgg aaatatcacc
    22861 aacgaaggca ctgttaaatt ccttgaaact tgcttagata actttgttaa atacgtagga
    22921 gtcgtttcga aattgaaaaa accaaaacca atcgaatcag aagacttgga ttgtggaaaa
    22981 ccaatcgcta caaccatcac agaagttgac cctgacgatc cagaatgggt agaaaaagtt
    23041 gcagcaatca ctggtgctgt ttctggtgat acctatgtca aattggacca cggtatccta
    23101 acagttaacc aaattgatat gttcttgaaa gctatgccat ttgaattgac atacgctgac
    23161 gacaacaacc aattcctcta ctacaacaac gctcaccaag atccagacac tatgttcgct
    23221 aaacgtgtac cacctcaatc aggtagccgt atgtcgactg ttcatggttc tcttccacca
    23281 gcacgtatga agaacgtaga gtgggttatc ggaacacttc gcaacggaaa ccaagaatac
    23341 gtccgtacga tcgttccagg ttctcctgca ggtgttatca acactcacaa ctaccaagca
    23401 atgtactatc ctgatggatc atacgctggt atcaatgaaa tcgtctttaa cttccaacca
    23461 tggcttgact ggtacctaaa agagactggt caacgtttgg tgggtggtag cggaccattt
    23521 gctcctgctg ccggaggtca tggagacgcc gatgctactt ctggcgcttc tgattcaggg
    23581 gatgctggag gccacggtgg tgacgcagac gctacagccg gtgcaagtta ctaatgatag
    23641 tttttaggaa ccattatggt tcctttttta gcgaaaaaag actagcaaac acaaactgct
    23701 agtctctttg ttatcgtttc atctatcttt gttaaaagaa agagtacata ttatgaattt
    23761 gggtcatcaa gactacggcc atgtaatcct ttttcacgtt gtacttggcg tagtttttct
    23821 ggtgtaacat cgtttccttc ttcgtccaca attttgattc cttcaatgtg atgacgaaca
    23881 gcgcgacgat aaccttcgat gtactcctca cgtagtttgg cttgttccac tttttcttct
    23941 agtgttaagc cttctgtttt tttcttttta gcaagctcat tgatacgagc aatttttttc
    24001 ggatccattt cttctccttt gtaataagat aaagtccgtt tatcaaattt tatttagtgt
    24061 taatttggtt aaaacaagca aacttagctg ctttcttggt tagttgtgac aagattgcca
    24121 aacgattttg acggacagcc tgatcttcag ccattaccat agtattttca aagaaagcat
    24181 caatgactgg gctaagcgca aagagttgtt tcaattgctg acttgcaggt cctgataaaa
    24241 cgagtgtttc tactgcttct gccaaagctt tttcttggtc attctcaaat agtgctgaat
    24301 caactgtagc acccccttct gccttctcag ccaggttaaa ggcacgagaa agtgattcaa
    24361 cagatggttt aaaatcttct tccttgctta cttctacgag agcacttgct gcttccaaca
    24421 tatctgccac aacaaagttt gaacctgcaa gaactgcttc cttgatatct tttggagtag
    24481 agcccatcat cttatcaaca cgagccttga taaagtccat aacctctgct ttattttcat
    24541 aagtcaaact gtcaaatttc aatgcataaa ggctatcaat cagctcatcc atagcaatgt
    24601 gccaaccaaa ggcatccaag atacgaacca caccttgagt tgcacgacga agggcataag
    24661 ggtcattaga acctgatgga atcaatccta ctgagaagaa actcaaaatc gtatccaatt
    24721 tgtctgcaat ggctagaact gcgccgacct tgctctctgg aagttctcct tcagctgatg
    24781 taggcatgta gtgttcacga atagcagctg ccaccgctgg agtttcacca gcaagaaggg
    24841 tgtatttttc acccataatt ccttggagtt cgtcaaattc accaaccata cctgtcaata
    24901 agtcaaactt gtaaatggct gctgcacgag caaggtcaac tgtttcatcc actgacaaac
    24961 cagctttttc tgccaaaagt acagtgattt gacccgtacg aatcatgtgt tcacgaaggg
    25021 aaccaatctt ctcatggaag gtgacattgt ttaatttttc aacaagatct gaaatcacca
    25081 atttttggtc ttcacgccag aagaattctc cgtcttccaa gcgggctacc aagacttttt
    25141 catttccttt gatgacattt ttcaaacgct ctgcgtttcc gttacgaaca gaaatgaagt
    25201 ttggcaagag ttttccatct tgatcacgaa caacaaagta acgctggtgt tccttcatag
    25261 aagtcaccaa gacttcttct ggaacttcaa ggtatttagc atcaaaactt cccatgaagg
    25321 cagttgggta ttcaaccaaa ttcaagactt cattcagcaa atccgcatca atttcgatac
    25381 gtacaccatg ttttgcctca atttccttga tttggtcaac aatcatttgc tcacgttcac
    25441 atggatctgc gattacaaac tgcttacgaa ggtcttcttc atagctcaat gctgactgaa
    25501 ttttggtttc tttccccaag aaacgatggc cacggctcac acgacttccc ttgatatcaa
    25561 ggaaatccaa gtcaaactct tgctcatcca agagaacagt taaagtgtgg acaggacgaa
    25621 tgtattcaaa gctgtttcca gcccagtgca tgctgacagg gaaagtcaat gacttcaaga
    25681 catctacaac accaggaaca atggcttcaa ctgcttgacc aacttcttcc ttagtgacat
    25741 agacatattc ttcacccttg atttcacgga attcgatatc ttcaacagtc aagccttttc
    25801 cacggacaaa tccttgagct gctttggtga agtttccatc actatccaag gcaattttct
    25861 ttgctggtcc cttgaaatct tctgtcaaat cagactgttt gtctgataaa ccagtcacac
    25921 gaacagccaa acgacgtggt gttgagaagg tttgaatggc ttcaaaagac aggcgttttc
    25981 ccttgaggaa ggctgccatt ttttcgccta gttgtttttc acttggtgtg acaacatagg
    26041 ctggtaattc ttcaagaccg agttctacta ataagttttt tgtcatgttt tttctccgaa
    26101 aagtatcttt ttattttcca gtttgcctta tgtgattggc acgcaagcaa ccaacttcgt
    26161 tgtttcattg ctaaaattgg agccaaaagt ctccaatttt gcctagtatc cttagtttca
    26221 ctaaggatac cttcatcact gcggcaactg gctcagggct cactctgttc gcccattttc
    26281 gtaatttgtc actctcttta ttctgcgtct tctgctaaga gtttagctcg tgtttcttca
    26341 tccaaaagtg ggtagcctag tcgtttgcgt tctgcgacaa aggttttggc tacgacacgg
    26401 gccaagttac ggatacgagc gatatagcct gcacgctctg ttacagatac ggcaccacgc
    26461 gcgtcaagca gattaaaggt atgtgaacat ttgagaacat agtcataggc agggtgtacc
    26521 aagccttctt ctaatgcacg accagcttct ttttcaaact tatcaaaatt ttcaagcaac
    26581 atttcttggt ccgaaatttc aaatgaatat tttgagtgct catactcagg ctggataaag
    26641 atttctccgt attttacacc atcagcccac tcgatatcat agacagagtc tacttcttga
    26701 atgtaagaag ccaagcgctc caaaccatag gtaacttccg cagtcacagg gctagttgcc
    26761 aatccaccga cttgttggaa ataagtgaac tgagtgattt ccattccgtc aagccaaact
    26821 tcccaaccaa gaccagctga accagttgat gggttttccc agttgtcctc aacaaaacga
    26881 atatcgtgct ccaaaggatt gattcccaat ttttccaaag actcaaggta aagttcttgg
    26941 atatttgatg gagaaggctt catgaccacc tggaattggt ggtgttggta gagacggtta
    27001 gggttttccc cataacgacc gtcagcagga cgacgtgatg gctctacata agctgcattc
    27061 catggctcag gtccgatagc acgaaggaaa gtgtaaggac tcattgtccc cgcacctttt
    27121 tcattgtcat aagcctgcat aagcatacaa ccttggtcat tccaaaattg ttgcaaagtc
    27181 aaaataattt cttgaaatgt taatttctta gacattgaat actccttaat aaaaaatgat
    27241 ttcttgcgac acgagtct
//
LOCUS       DBERXF010000031        25291 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.31, whole genome shotgun sequence.
ACCESSION   DBERXF010000031 DBERXF010000000
VERSION     DBERXF010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25291
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.31"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            87..1262
                     /gene="mutY"
                     /locus_tag="ACL8JK_001442"
     CDS             87..1262
                     /gene="mutY"
                     /locus_tag="ACL8JK_001442"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGS1786309.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1318..2022
                     /gene="yycF"
                     /locus_tag="ACL8JK_001443"
     CDS             1318..2022
                     /gene="yycF"
                     /locus_tag="ACL8JK_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGS1786310.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2015..3364
                     /gene="vicK"
                     /locus_tag="ACL8JK_001444"
     CDS             2015..3364
                     /gene="vicK"
                     /locus_tag="ACL8JK_001444"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HGS1786311.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3366..4175
                     /locus_tag="ACL8JK_001445"
     CDS             3366..4175
                     /locus_tag="ACL8JK_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGS1786312.1"
                     /translation="MSKIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4266..4508
                     /gene="relB"
                     /locus_tag="ACL8JK_001446"
     CDS             4266..4508
                     /gene="relB"
                     /locus_tag="ACL8JK_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGS1786313.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4510..4764
                     /locus_tag="ACL8JK_001447"
     CDS             4510..4764
                     /locus_tag="ACL8JK_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGS1786314.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4811..5554
                     /locus_tag="ACL8JK_001448"
     CDS             4811..5554
                     /locus_tag="ACL8JK_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006811 - monoatomic ion transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HGS1786315.1"
                     /translation="MNKKWLFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     NSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILLEKQSEKIEELH"
     gene            complement(5855..6841)
                     /locus_tag="ACL8JK_001449"
     CDS             complement(5855..6841)
                     /locus_tag="ACL8JK_001449"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGS1786316.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7035..9503
                     /gene="gyrA"
                     /locus_tag="ACL8JK_001450"
     CDS             7035..9503
                     /gene="gyrA"
                     /locus_tag="ACL8JK_001450"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGS1786317.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLVITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            9503..10246
                     /gene="srtA"
                     /locus_tag="ACL8JK_001451"
     CDS             9503..10246
                     /gene="srtA"
                     /locus_tag="ACL8JK_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HGS1786318.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSNEILTAFNQPYKQFY"
     gene            10490..11287
                     /locus_tag="ACL8JK_001452"
     CDS             10490..11287
                     /locus_tag="ACL8JK_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGS1786319.1"
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            11435..12694
                     /locus_tag="ACL8JK_001453"
                     /pseudo
     CDS             11435..12694
                     /locus_tag="ACL8JK_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
     gene            12790..14064
                     /locus_tag="ACL8JK_001454"
     CDS             12790..14064
                     /locus_tag="ACL8JK_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HGS1786320.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRQEKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            14074..14952
                     /gene="truB"
                     /locus_tag="ACL8JK_001455"
     CDS             14074..14952
                     /gene="truB"
                     /locus_tag="ACL8JK_001455"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGS1786321.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLYEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVIIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALSLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            15193..15495
                     /locus_tag="ACL8JK_001456"
     CDS             15193..15495
                     /locus_tag="ACL8JK_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGS1786322.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            15603..16241
                     /gene="udk"
                     /locus_tag="ACL8JK_001457"
     CDS             15603..16241
                     /gene="udk"
                     /locus_tag="ACL8JK_001457"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGS1786323.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            16369..17709
                     /gene="xseA"
                     /locus_tag="ACL8JK_001458"
     CDS             16369..17709
                     /gene="xseA"
                     /locus_tag="ACL8JK_001458"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGS1786324.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEDLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            17687..17899
                     /locus_tag="ACL8JK_001459"
     CDS             17687..17899
                     /locus_tag="ACL8JK_001459"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGS1786325.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            17896..18771
                     /locus_tag="ACL8JK_001460"
     CDS             17896..18771
                     /locus_tag="ACL8JK_001460"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGS1786326.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQIPFE
                     TESIVSVVESLRING"
     gene            18764..19579
                     /locus_tag="ACL8JK_001461"
     CDS             18764..19579
                     /locus_tag="ACL8JK_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGS1786327.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            19572..20003
                     /locus_tag="ACL8JK_001462"
     CDS             19572..20003
                     /locus_tag="ACL8JK_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS1786328.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            20010..21677
                     /gene="recN"
                     /locus_tag="ACL8JK_001463"
     CDS             20010..21677
                     /gene="recN"
                     /locus_tag="ACL8JK_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGS1786329.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDKQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSYLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            21679..22407
                     /locus_tag="ACL8JK_001464"
     CDS             21679..22407
                     /locus_tag="ACL8JK_001464"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS1786330.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            22486..24309
                     /gene="lepA"
                     /locus_tag="ACL8JK_001465"
     CDS             22486..24309
                     /gene="lepA"
                     /locus_tag="ACL8JK_001465"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGS1786331.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(24390..24722)
                     /locus_tag="ACL8JK_001466"
     CDS             complement(24390..24722)
                     /locus_tag="ACL8JK_001466"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786332.1"
                     /translation="MKIKEQTRKLAAGYSKHSFEVVDKTDEVSSKHDFEVVDETDEVS
                     SKHDFEVVDETDEVSSKHGSEVVDETDEVSSKHGSEVVDETDEVSNHTYGKATLTWFE
                     EIFEEYKN"
     gene            24902..>25291
                     /locus_tag="ACL8JK_001467"
     CDS             24902..>25291
                     /locus_tag="ACL8JK_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1786333.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDF"
BASE COUNT         7665 a         4478 c         5805 g         7343 t
ORIGIN      
        1 tagatagaaa agttatatac tatctattga aaatattata aatcagatac aaagacaggt
       61 gaaaccttct gtgttatact agagatatgt tagatttgaa agaatacggt atcgtcatgt
      121 ggccggagga gaaagtcatt tctttccgtg agaaacttct cgcttggtat gatgaaaaca
      181 aaagagattt gccttggagg agaagtaaaa atccttatca catctgggta tctgaaatca
      241 tgcttcagca gaccagggtg gatacagtta tcccttacta cgaaagattt ttggactggt
      301 ttccaactgt cgaaagtctg gcaactgcgc ctgaggagag tttactgaaa gcttgggagg
      361 gcttgggcta ttattctcga gttcgcaata tgcaggctgc agcccagcag attatgactg
      421 actttggtgg ccaatttcca aatacctatg aaggaatttc cagcttgaaa gggattggac
      481 cttacacagc aggagccatt tccagtattg cttttaactt gcctgagcca gctgtagatg
      541 gtaatgtcat gcgggtcttg gcgcgtctgt ttgaagtcaa ccacgatatt gggattccaa
      601 gtaatcgaaa aatttttcag gcaatgatgg agatcttgat taatccggat cgtccgggtg
      661 attttaatca agcattgatg gacttagggt ctgatattga gtctcctgta aatcccagac
      721 ctgaagaaag cccagtcaag gactttagtg cggcatatca gaatggaacc atggaccgtt
      781 atccaattaa atctcctaag aaaaagccgg ttcctattta tcttaaagcc ttagttgtga
      841 aaaattctca aggacaattt ttacttgaaa aaaatgaaag cgaaaagctc ttggcaggtt
      901 tttggcattt cccctttata gaagttgata acttttcgca agaagagcag tttgacctct
      961 ttcatcaggt tgcggaagaa agtgtgaact ttggtcccag tccagaagag agtttccagc
     1021 aggactatga cctagatgtt gattggcttg atgtttgttt tgatacagtc cagcatgttt
     1081 ttagtcatcg aaaatggcat gtacagattg tagcaggtca ggtgagtgac ttccatgatt
     1141 tttcagatag ggaagttcgt tggctttcac cagaagaatt caagaattac ccacttgcca
     1201 aaccccaaca aaaaatctgg caggcttatg cacaagccaa cttagacagt agccaagact
     1261 agctattgtg tcttctgact atttttttgg tataatagta gagaaaaagg tgaacatatg
     1321 aaaaaaatac taattgtaga tgatgagaaa ccaatctcgg atattatcaa gtttaatatg
     1381 accaaggaag gttacgaagt tgtaactgct tttaatggtc gtgaagcgct agagcaattt
     1441 gaagcagagc aaccagatat tattattctg gatttgatgc ttccagaaat tgatggttta
     1501 gaagttgcta agaccattcg taagacaagc agtgtgccca ttcttatgct ttcagccaaa
     1561 gatagtgaat ttgataaggt tatcggtttg gaacttgggg cagatgacta tgtaacgaaa
     1621 cccttctcca atcgtgagtt gcaggcgcgt gttaaagctc ttctgcgtcg ttctcaacct
     1681 atgccagtag atggtcagga agcagatagt aaacctcaac ctatccaaat tggggattta
     1741 gaaattgttc cagacgccta cgtggctaaa aaatatggcg aagaactaga cttaacccat
     1801 cgtgaatttg agcttttgta tcatttagca tcgcatacag gtcaagtcat cacgcgcgaa
     1861 cacttgcttg agactgtctg gggttatgac tattttggtg atgtccgtac agttgatgtg
     1921 actgtacgac gtctgcgtga gaagattgaa gatacgccca gccgaccaga gtatatcttg
     1981 acgcgccgtg gtgtagggta ttacatgaga aataatgctt gatttactga aacaaaccat
     2041 ttttaccaga gattttatct ttatcctgat tttgttaggt ttcatccttg ttgtgaccct
     2101 cttattactg gaaaatagac gtgataatat tcagttgaag caaatcaatc aaaaggttaa
     2161 agatttgatt gcaggagatt attccaaggt tcttgatatg caaggtgggt ctgaaatcac
     2221 caatattacc aataatttga atgacttgtc ggaggttatt cgtctcactc aggaaaatct
     2281 agaacaagag agtaagaggc taaatagtat tctgttttat atgacagatg gggttcttgc
     2341 gaccaaccgt cggggtcaga ttatcatgat taacgataca gccaagaagc aactggggtt
     2401 ggttaaggaa gatgttctga atagaagcat tttggaattg ctcaagatag aagaaaacta
     2461 tgaattgcgt gatttgatta cccaaagtcc agaattgttg ctagattccc aagatatcaa
     2521 tggtgaatat ttgaaccttc gagttcgctt tgccttgata cgtcgagagt ctggctttat
     2581 ttcaggtttg gtggctgttt tgcatgatac gacggagcag gagaaggaag aacgcgaacg
     2641 aagactcttt gtttccaatg ttagccatga gttacggact cctctgacta gcgtaaaatc
     2701 ctatcttgaa gccttggatg agggggcttt gtgtgaaact gtagcaccag actttatcaa
     2761 ggtttctctt gatgagacca accgtatgat gcgcatggtg acggatctcc tccatctttc
     2821 acgtattgat aatgctacca gtcacctaga tgtggaactg attaacttca ctgcttttat
     2881 tacctttatc ctcaatcgtt ttgacaagat gaaaggacag gaaaaggaga aaaaatatga
     2941 gttggtgaga gattatccca tcaattctat ctggatggaa attgatacag ataagatgac
     3001 gcaggttgtc gacaatattt taaataatgc tattaagtat tcgccagatg ggggtaaaat
     3061 cactgtcaga atgaagacaa ctgaagacca gatgatttta tccatttctg accacggttt
     3121 ggggattcct aagcaggatt taccacgtat ctttgaccgt ttctatcgtg tggatcgtgc
     3181 tagaagtcgt gcacaaggtg gtacaggtct aggactgtct atcgctaaag aaattattaa
     3241 acaacataag ggctttattt gggccaagag tgaatacggc aagggttcaa cctttaccat
     3301 tgtgctccct tatgataagg atgcagtgaa agaagaagta tgggaggatg aagtagaaga
     3361 ctagaatgag taaaataggc tttaaataca gtattttagc gtcgggttcc agtggaaatt
     3421 ctttttatct ggaaacctca aaaaagaagc ttttagtgga tgcaggcttg tctggcaaga
     3481 aaattaccag tctgctagct gaaattaacc gcaagccaga agacctggat gccatcttga
     3541 ttacccatga gcattcagat catatccatg gagtaggcgt tttggctcgc aagtatggta
     3601 tggatcttta tgccaatgaa aagacctggc aagctatgga aaatagtaaa tatcttggca
     3661 aggtggattc ttcgcaaaag catatttttg aaatgggtaa aaccaaaact tttggagata
     3721 tcgacatcga gagttttggt gtaagccatg atgcagtcgc accgcagttc tatcgcttta
     3781 tgaaggatga caagagtttt gtccttttga cagatacagg ttatgtcagt gaccgtatgg
     3841 cgggcattgt cgaaaatgcg gatggctatc ttatcgaggc caaccatgat gtagagattt
     3901 tgcgatcagg ttcttacgct tggcgactca aacaacgaat cctatctgac cttggtcacc
     3961 tttctaacga ggacggtgct gaagctatga ttcggacgct aggaaatcgt actaagaaga
     4021 tttaccttgg gcatttatct aaggaaaaca atatcaagga actggctcat atgaccatgg
     4081 tcaatcagct ggctcaagct gatctgggag tcggagtaga ctttaaggtt tatgatacct
     4141 caccagatac cgcaacacca ttgacagaga tatagaaaga acgctgagaa ggtgttcttt
     4201 ttatattgac tgaacaccta aaaagtaata caatggtgtt accattaaaa aagggagcac
     4261 aaaagatgac tactattaca ttaaaagttt ctgaagctga taaaacattt atgaaagcaa
     4321 tggctaagtt tgaaggagtt tccctttcgg aacttattcg caccaaaact cttgaagccc
     4381 tagaagatga atacgatgct cgtgtggcag atttagccta tcaagagtat ttagaagact
     4441 tggaaaaagg agttgaaccc attacttggg aagaaatgat gcatgattta ggcttgaagg
     4501 atgaataatt tgtataaatt agttccaaca agacgtttca tcaagcaatt gaaaaaattg
     4561 gaccgttata cgcagaagct aattacaaac tatttacaaa ccaatgtttt ggaagaccca
     4621 agacgacacg gaaaggcttt ggttggtaat cgcgttggtc aatggcgcta tagaattggt
     4681 aattatcgag ttatcgtaca aattgtagat gatgaattag tcgttgctac tctagaagtt
     4741 ggtcatcgga gagatattta ttgaattaaa gctgagtaat aacagtatag aaagtaagga
     4801 tagtaaaaat ttgaataaaa aatggttatt tgcagattat tatgatacaa caattatttt
     4861 acttgcttta atctctgtta ttctggtatt acttggattt gctgagatga ttgatttgga
     4921 caatccgcct tatagtatta ttgatttagt aatctggggt gtttttgtaa ttgattatag
     4981 ttggcgcttt tttacgacta aaagaaaatg gcgctttatt cttgaaaata tttttgattt
     5041 attggctatt ctccctttaa atgctatttt tacagtgttt cgattagggc gtatctttcg
     5101 tttagctaaa ctaacaaaat tactgaaact gactcgttta cttagaataa ttggacttac
     5161 aggtaaatta gaaagaaaaa ttagtagatt cttacggaca aatggcctga tttatatctt
     5221 gtatgttaat atctttattg ttttagtagg gagttcgatt ttatccgttg ttgaagaaaa
     5281 atccttctca aatagtcttt ggtgggctct tgtgacagta actactgttg gatatgggga
     5341 tattgttcct gcttccattt ttgggaaatg gctagcagtt ttactgatgc ttgtcggtat
     5401 tggaacaata gggatgttaa caagtgcttt gacgaacttt tttgtaaagg ataatccaga
     5461 tgaacagata aaacttgata aactcaaaga tgaattatcg agccaaagaa tattactaga
     5521 gaaacaatct gaaaaaatcg aagaactaca ttgaatgata aaagatttag ttgaaaaaat
     5581 atcataaagg tgagacaaaa caaaacttga ttcgaggaga aatcaagtaa gtcttgacac
     5641 aatagaacgc atattatcag gtataaaaac ttgatactat gcgttttata gagaaataaa
     5701 ataaaatctg aacaaatcaa ttaggaattt aaagcatttt ataacaacgt tttagagtga
     5761 tagggtgcta tttcaacttc aacctactat aatacagaaa aaaatacagg aaaaaacaac
     5821 tccctgatga ttcaaggagt tgtctatagt taaattagtt tttagaagct tcttggaatt
     5881 ctggattttt ccatgcttcg tcaataatag cttgcaattc tttagcagat gcttgcattt
     5941 tttgagtttc tgcatcgttc aatggaatgt ttactggacg aacgatacca tgtgcaccaa
     6001 caacagctgg ttgaccgata aagacattct caactccgta ttgaccttct tggaatactg
     6061 aaagtggaag tactgcgttt tcatcgtcaa ggattgcttt agtgatacga gcaagggcta
     6121 ctgcgatacc gtagtatgtt gcaccttttt tgttgatgat tgtgtaggct gcatcacgaa
     6181 caccttcgaa caattcaatc aattcagctt cttgaacatt ttgagtgtct ttaagaaatt
     6241 cttcaaggtt tacaccagcg atgttagcgt gtgaccaaac agcgaactca gagtcaccgt
     6301 gttcacccat gatgtaggcg tgcactgaac gagcatccac atccaatttt tcagcaagtg
     6361 cttgacggaa acgagctgag tcaagtgaag tacctgaacc gataacgcgt tctttaggga
     6421 aaccagagaa tttccaagtt gagtaagtca aaacgtcaac tgggttagca gcaacaagga
     6481 agataccttt gaaaccagat tcaacaactt gagttacgat tgatttgttg atagcaaggt
     6541 ttttacctac aaggtcaaga cgagtttcac ctggtttttg aggtgcacct gcagtgatca
     6601 caacaaggtc agcgtctgca cagtcagagt attgagctgc atagattttt ttaggtgaag
     6661 tgaaggcaag ggcgtgacta aggtcaagcg catcaccaac agctttttca tgcaattgtg
     6721 gaatttcgat aattccaagc tcttgtgcaa ttccttggtt aacaagtgca aaagcgtaag
     6781 atgaacctac agcaccatca ccgacaagga taactttttt gtgttgttta gttgaagtca
     6841 ttgttttaaa catctcctta attttattag gggattttcc ctagacaact tcattctatc
     6901 acttttaaaa aactttgtca cgaatatgcc ttatagttct cgatgtaaac gttttagtgg
     6961 tttagaggct gaaatagatg ggaatttatg gtataatgtt gttacttact aattgtgaaa
     7021 tgaggcattt attaatgcag gataaaaatt tagtgaatgt caatctgaca aaggagatga
     7081 aggcaagttt tatcgactac gccatgagtg ttatcgtagc gcgagctctt cctgatgttc
     7141 gagatggctt aaaacctgtt caccgtcgca ttctctacgg aatgaatgaa ttgggtgtga
     7201 ccccagacaa accccataaa aaatctgctc gtattacagg ggatgtcatg ggtaaatatc
     7261 acccacacgg ggattcctct atttatgaag ccatggtccg tatggctcaa tggtggagct
     7321 accgttacat gcttgtagat ggtcatggga attttggttc catggatgga gatagtgctg
     7381 ccgctcaacg ttataccgag gcacgtatga gcaagattgc tctggaaatg cttcgtgata
     7441 tcaacaaaaa tacagttgat ttcgttgata actatgatgc caatgaacgg gaacccttgg
     7501 tcttgccagc gcgttttcca aaccttttgg ttaatggagc aactggtatc gcggttggga
     7561 tggcaaccaa tattccacct cataatctgg gtgaaaccat tgatgcagtg aagttggtca
     7621 tggataatcc tgaagtgact accaaggact tgatggaagt cttgcctgga ccagattttc
     7681 caactggtgc tcttgtcatg gggaaatcag gtatccataa ggcttatgaa acaggtaaag
     7741 gttcgattgt cctacgttct cgtacagaga ttgaaacgac taagactggt cgtgagcgta
     7801 tcgttgtaac agaatttcct tacatggtca ataaaaccaa ggtgcatgag catattgttc
     7861 gcttggttca ggaaaaacgc attgagggta tcacagcagt acgtgatgag tcaaaccgtg
     7921 aaggtgttcg atttgttatt gaagtcaagc gcgacgcctc agccaatgtt attctcaata
     7981 acctcttcaa aatgacccaa atgcaaacca attttggttt caatatgctc gctatccaaa
     8041 atggtatacc gaaaattttg tctcttcgtc agattttgga tgcttatatc gagcaccaaa
     8101 aagaagtggt tgttcgtcgt acacgttttg ataaggaaaa agcggaagcg cgcgctcata
     8161 tcttagaagg tctcttgatt gcgctagacc atatcgacga agtgattcgt atcatccgtg
     8221 ctagtgaaac ggatgcggaa gctcaagctg agttgatgag caagtttaag ctttctgaac
     8281 gtcaaagtca agctatcctt gatatgcgtc ttcgtcgttt gacaggtttg gaacgcgata
     8341 agattcaatc tgagtatgat gacctcttgg ctctgattgc ggatttagca gatattcttg
     8401 ctaagcctga acgtgtttct caaattatca aagacgaatt ggatgaagtt aaacgtaaat
     8461 tttctgataa acgccgtaca gagttgatgg ttggacaggt cttgagtctc gaggatgagg
     8521 acttgattga agaatcggat gtcttgatta ccctttctaa cagaggctac attaagcgtt
     8581 tggatcagga cgagttcact gctcaaaaac gtgggggtcg tggtgtccaa ggaacgggag
     8641 tgaaagatga tgactttgtt cgtgagttag tgtcaactag cacccatgat catctgctct
     8701 tcttcacaaa caagggacgt gtctatcgtc ttaaaggtta tgaaattcct gagtatggtc
     8761 ggactgccaa agggctacca gtagtcaatc tcttgaaatt ggatgaagac gaaagtattc
     8821 agacggttat caatgttgag tctgatcgca gtgatgatgc ttatctcttc tttacaaccc
     8881 gtcacggtat tgtgaagaga accagtgtta aggagtttgc caatattcgt caaaatggtc
     8941 tcaaagcgct gaatttaaag gatgaagatg agttaatcaa tgtcttgttg gcagaaggag
     9001 atatggatat tatcattggt accaagtttg gttatgcagt tcgctttaat caatcagccg
     9061 ttcgtggtat gagccgtatc gccactggtg tgaaaggtgt taaccttcgt gaaggagaca
     9121 cagttgttgg tgccagcttg attactgatc aagatgaggt tcttgttatc acagaaaaag
     9181 gatatggtaa gcgtacagtc gctactgaat acccaacaaa aggtcgtggt ggtaagggaa
     9241 tgcagacagc taaaattacc gaaaaaaatg gcttgctggc cggtcttatg actgttcaag
     9301 gggatgagga tttgatgatt atcactgata caggtgtcat gattcgaacc aatcttgcca
     9361 atatttcaca aacaggacgt gcaactatgg gagttaaagt aatgcgcctg gatcaagatg
     9421 ctcagatagt gactttcaca acggttgcgg tggcagaaaa agaagaagtt gggacagaaa
     9481 acgaaacaga aggtgaagca taatgtctca aaaaaataat aaaaagaaaa acaagcgaaa
     9541 aaatttgctg acaaatatcc tagcaggatt tctgatatta ctgtcactgg ctttgatttt
     9601 taatactcaa attcgaaata ttttcatagt ctggaatacc aataagtatc aagttagcca
     9661 ggtatcaaaa gaaaaattag aagaaaatca ggatacagaa ggcaattttg actttgattc
     9721 tgtcaaagct atctcttcgg aagctgttct aacttctcaa tgggatgctc aaaaattacc
     9781 agttattggg ggaattgcaa ttcctgaatt ggaaatgaat ttgccgattt ttaaaggact
     9841 tgataatgtt aatctcttct acggagctgg tacaatgaaa cgcgagcaag taatgggaga
     9901 aggaaattat agtctagcta gtcaccatat ctttggtgtt gataatgcta ataaaatgtt
     9961 attttctcct ttagataatg ctaaaaatgg catgaagatt tatctaaccg ataaaaataa
    10021 agtttatact tatgaaatac gtgaagtcaa acgtgtgaca ccggatcgtg ttgatgaagt
    10081 tgatgataga gatggggtca atgaaatcac attagtaacc tgtgaagacc ttgctgctac
    10141 agaacgtatt attgtcaaag gtgatttgaa agaaacaaaa gattattcac aaacatctaa
    10201 tgaaatccta acagctttca atcaaccata taaacaattt tattaataca aatcagtgaa
    10261 atccatgatt tcactgattt tttaagattt tcataaaaat atagtaaaat gaaataagaa
    10321 taggacgaat cgttcaggac agtcaaatcg atttctaaca atgttttaga agtagaggtg
    10381 tactattcta gtttcaatct actataaact tttatgaaat acagaaaacg cttcctaaaa
    10441 cctaaagttt gtgatataat tatcaagaaa aaagatttag gagtttatta tgatttcttc
    10501 agaatttatc tcaaagattg aatttgcttg caataagaaa gaaagtcttt atagtcaaag
    10561 caaatttaag tatgcgattc gttcgatgtt cgcaggtgca tttttaacct tcagtactgc
    10621 tgcaggtgca gttggggctg acttgattaa taaaattgca ccaggtagtg gacgcttcct
    10681 ctttccattc gtttttgctt ggggcttggc ctacattgtt tttttgaatg ccgagttggt
    10741 cacttcaaac atgatgttct tgactgctgg tagtttctta aaaaaaatct cttggagaaa
    10801 aacagctgag attttactat actgtacctt gttcaacctt atcggagcct tgatagcagg
    10861 gtggggcttt gctcattcgg cagcctatgc gaatctgaca cacgatagtt tcatctcagg
    10921 tgttgttgag atgaagttag gccgctcaaa tgaattggtc ttgcttgagg cgattttggc
    10981 aaatattttc gtaaatattg cgattctgtc atttattttg gtcaaagatg gtggtgccaa
    11041 actttggctt gtgttgtcag ctatttacat gtttgtattc ttaacaaacg agcacattgc
    11101 ggcgaacttt gcttctttcg cgattgtgaa attcagtgtt gctgcggatt caattgccaa
    11161 cttcggtgtt ggaaatatgc ttcgccactg gggtgtgact ttcatcggaa actttatcgg
    11221 aggaggcctc ttgatgggtc ttccatatgc cttcctcaat aaaaacgaag atacttatgt
    11281 agattaagaa aatgagcacg attgagtcgt gcttttttca ttttcaaaat aaggtaatag
    11341 ctatttctta tatcaaaata tagaaaactg atatttgtaa actataactc aaggtgctac
    11401 aatatcctta ataaaatgat atggaggtca ccttatgact tgtgatttta aatctgaaac
    11461 tctacaacta catgctggtc aagttgtggc tccagctact aagtctcgtg cagtgccgat
    11521 ttatcaaaca acattttttg tttttgatga cacgtaggaa ggtgccgatc tgtttgcctt
    11581 gaggaaacca gggaacattt atactcgtat caccaatcct acaacagctg cccttgaagg
    11641 tggtgttgaa gcgctagcaa cagcatcagg tatgactgca gtgacttata cgattttggc
    11701 gcttgcccat gctggtgacc atgtagtggc tgcttcgact atttacggtg gaaccttcaa
    11761 tcttttgaaa gaaccccttc ctcgttatgg tatcacaaca acctttgtcg atattgataa
    11821 tttggaggaa gtagaagcag ctatcaaaga caataccaag cttgtcttga ttgaaacctt
    11881 gggtaacccc ttgattaata ttccagacct ggaaaaactg gcagagattg ctcataaaca
    11941 tcaaatccca cttgtgtcag acaatacttt tgcaacacct tatttgatta acgtcttctc
    12001 tcatggcgtt gacattgcca ttcactctgc gactaagttt atcggtgggc atggtacaac
    12061 tattggagaa ataattgtcg atagtggtcg ttttgactgg acggcttcag ggaaattccc
    12121 tcaatttgtt gacgagggtc caagctgcca caatttgagt tatactcgtg atgtgggtgc
    12181 agcagccttt attatagctg ttcgagttca attgcttcgt gatacaggtg cagccttgtc
    12241 accattcaat gctttcctct tgctacaaag acttgaaacc ctttcacttc gtgtggaacg
    12301 ccatgtacaa aatgctgaga caattgttga ttttcttgtc aaccatccta aggtagaaaa
    12361 ggtaaattat ccaaaacttg cagatagtcc ttattatgcc ttggctgaga aatacttgcc
    12421 aaaaggtgtc ggttcaatct ttaccttcca cgtcaaaggt gacgaggaag aagcacgcaa
    12481 ggtcattgat aatttagaaa tcttttctga ccttgcaaac gcggcagatg ctaaatcgct
    12541 tgttgtccat ccagcaacaa tcactcacgg tcaattgtca gaaaaagacc tagaagcagc
    12601 aggtgtcaca ccaaatcaaa tccacttgtc tatcggtctt gaaaatgtag aagatttgat
    12661 tgaagactta cgcttggcct tggaaaaaat ttaaagtaaa agaagataaa cagtgggttt
    12721 tgactcactg tttttgattt tccctcaggc atgatataat ggttacagaa gtctagaaag
    12781 aggaatgtaa tgaacgaaat caaatgtccc aactgtgggg aagtctttac agtaaatgaa
    12841 agccagtatg ctgaactttt gtcccaagtg agaacggcag agtttgataa ggaactacac
    12901 gataggatga ggcaggaact ggccttggct gagcaaaagg ctatgaatga gcaacagact
    12961 aaactggctc agaaggatca agaaattgcg caattgcaga gtcaaatcca aaactttgat
    13021 acagaaaaag aattggccaa gaaagaagtt gaacagacaa gccatcaggc cttattggct
    13081 aaggacaagg aagtacaggc cttggaaaac cagttggcga ccttgcgttt ggagcatgaa
    13141 aatcaattgc aaaagaccct ttctgaccta gaaaaagaac gcaatcaggt caaaaatcag
    13201 ctcctactgc aagaaaagga aaatgagttg tctttggctt ctgttaagca aaactacgaa
    13261 gcccagctca aagcagccag tgaacaagtc gagttttata agaattttaa ggctcaacaa
    13321 tctacaaaag cgattgggga aagcctagaa cagtatgcag agagtgagtt taacaaggtt
    13381 cgtagtttcg cctttccaaa tgcttacttt gagaaggata acaaggtctc ttcgcgtggg
    13441 tctaaagggg actttatctt ccgtgagtgt gatgaaaatg gagttgaaat catttctatc
    13501 atgtttgaga tgaaaaacga agcggacgga acagagaaga agcacaagaa tgcagatttt
    13561 tacaaggaat tggacaagga ccgtcaggag aagaactgtg agtatgccgt tttggtgacc
    13621 atgcttgagg ccgataatga ctactttaac acagggattg ttgacgtcag ccacgagtat
    13681 gaaaaaatgt atgttgttcg tcctcaattc tttatccagt tgattggtct cttacgtaat
    13741 gcggcgctaa attccctaaa atacaagcag gagttggcct tggttcgcga gcaaaatatt
    13801 gacattacgc attttgagga agatttggat gcctttaagc tagcttttgc taagaactat
    13861 aattcagctt cgactaactt tggaaaagct attgatgaaa tcgacaaggc catcaaacgc
    13921 atggaagagg ttaagaaatt cctgactaca tctgaaaacc aactccgtct agctaacaac
    13981 aaattggaag atgtctctgt taaaaaattg acccggaaaa atccaacaat gaaagcgaag
    14041 ttcgaagcac tgaaggggga gtagaaagca aaaatgaacg gtattatcaa cttaaaaaaa
    14101 gaagcaggaa tgacctcgca tgatgcggtt tttaaactgc gtaagatttt gggaaccaag
    14161 aaaattggtc atggtggaac cttggatccg gatgtggtgg gtgttttgcc gattgcggtt
    14221 ggcaaggcga cacgcatggt cgagtttatg caggacgagg gtaagatcta tgagggggaa
    14281 attactctgg gttattccac gacgactgag gatgctagtg gggaagtgat cgcagaaacc
    14341 cctgttttgt ctcccttgta tgaaaagctt gttgatgaag cgattgctag cttgactggg
    14401 cctattaccc agattccccc tatgtattcg gcagttaagg ttaatggtcg caagctctat
    14461 gagtatgcgc gtgctggtca ggaagtggag cgtccagaac gtcaggtgat catttatcaa
    14521 tttgagcgaa caagtccgat ttcttatgat ggccaacttg cccgattcac ttttcgtgta
    14581 aaatgcagta aagggactta catccgtact ttgtcagttg atttgggtga aaagcttggt
    14641 tatgcggctc atatgtccca tttgactcgt actagtgctg ctggcttaca attagaagac
    14701 gctctttcct tggaggaaat tgctgaaaaa gtagaggctg ggcaattaga ttttctccat
    14761 cctttagaga ttgggacagg tgaccttgtc aaagttttcc taactccaga agaggctaca
    14821 gaagttcgct ttggtcgttt tattgagcta gaccaaacgg acaaagaact ggctgccttt
    14881 gaagatgata aattgttagc cattctagaa aaacggggca atctctataa gccaaggaag
    14941 gtttttagct agatcgttta ggaataaaaa tcgggtgata gataacaatt gcttgataaa
    15001 accccatact aatagtagaa tggttttggg aattataata ttccaattgt tgcgagttgt
    15061 aggtactcaa ataatctata tagaaattta gaggtgtgaa atgaagcaat ttaaaattct
    15121 ttcagataaa tatttagagt ccattacagg ttctggtggg aacttaggcc caggatttgg
    15181 tgtgataatt ccatgatgcg aaatgagttt cgagaaaggg tggagcaact tcttcaacaa
    15241 aaagaaataa atgaaaatag tgagttgagt cacctgtttc gtcttgctat acaaaattta
    15301 gacagaaatg aaaaatacca atcggtcatg gccaatttga gtcaagggtt gtcactttac
    15361 ctcatgacgc atcattacca ggcacctaag tctgtcattg attttggttt atggattgcc
    15421 aaagctccta gccaggaaag agggagactg gctttcttgc agatgcttgc tcaaacccta
    15481 cagggctttc gttaaaactg tcgaacatca gagggaagac tctggtgttt tttgctgatg
    15541 agactataaa ttttgtaaaa aatgtgatag aatagacgac ggataaaata acggaggata
    15601 gcatgcaaaa tagaccaatc attattggag tgacaggtgg ttctggtggt ggtaaaacca
    15661 gtgtttcaag agccatttta tcgcattttc ctgatgaaaa gatttccatg attgagcatg
    15721 attcatacta caaggatcag tctcatttga cctttgaaga gcgtgtcaaa accaactatg
    15781 accatccttt tgcctttgat acagacttga tgatcgagca gattaaggaa ttgttggcag
    15841 ggcgtccggt ggacatcccg acctacgact atacagagca tacacggagt agcaagacct
    15901 atcgtcagga gcctcaagat gtctttatcg ttgagggcat tttggtcttg gaggacaagc
    15961 gtctgcgcga tttgatggat atcaagattt ttgtggatac ggatgacgat gtgcgcatta
    16021 ttcgtcgtat caagcgtgat atggaggagc gtggccgtag ccttgatagc gttattaacc
    16081 agtacttagg tgtggtcaaa ccaatgtacc accagtttat cgagtcaact aagcgttatg
    16141 ctgatatcgt cattcctgaa ggggttagca ataccgtggc tatcgacctg ttgacgacca
    16201 agattgcaaa gattttggaa gaagctcgaa acagcaaata atcacatgtg gaggccttgc
    16261 ctcctttttc tatttttccc tcataatggt acataaatgg agatttttag gcatattttt
    16321 ggtataataa tacccatgaa agagcaagta aatgaatagt aggtggagat ggaaaagtat
    16381 ttatcggtaa caactttgac caagtatctg aaaatgaaat tcgataaaga cccatacttg
    16441 gaacgggtct atttaactgg tcaagtttcc aactttcgta aacgacctac tcaccaatat
    16501 ttctccctaa aggatgacca tgcagttatt caagcgacca tctggtctgg gatttatcag
    16561 aaattagggt ttgacctgga agaaggaatg aagatcaatg tgattgggcg tgtacaggtc
    16621 tatgaaccaa gtggtagcta ctccatcatc attgaaaaag ctgagcctga tggggttggg
    16681 gcgcttgcga ttcagtttga acaacttaag aaaaaattga cagaagaaga cctgtttcaa
    16741 gaacgcttca agcaagctct gccccaattt tctaagagaa ttggtgtagt aaccagccgt
    16801 agtggagccg ttattcgaga tattatcacg accgtcagca ggcgattccc aggtgttgac
    16861 atccttcttt atccgaccaa ggttcaaggt gaaggggctg cggaggaaat tgctagaaat
    16921 attgcgcgtg ctaatcaacg ggacgatttg gatttgctca ttattggtcg tggaggtggt
    16981 tctattgagg atctctgggc ctttaacgaa gaaattgtgg tacgagctat ttttgaatct
    17041 cgtttaccag ttatctctag tgtggggcat gagacggatg tgaccttggc agattttgtg
    17101 gcagatcgac gcgctgcaac gccaacagcg gcggctgaac tggcaacacc tgtgaccaag
    17161 ttggatgtat tagctcattt gcaaaatcag gaaaaacgga tggcaacggc agtccgaaat
    17221 gttctatcta agaaacaaga ggctttgaaa aaatgcagtc agtctgttat ctttagacaa
    17281 cctgagcgct tgtatgacgg ttatttgcaa cgcttggacc aactgcaact gcgtttgaaa
    17341 caaagtttgc gaactcggat ttctgataac aaacaattag ttcaagcaag aactcatcaa
    17401 ttagtacaat tatcacctgt taccaaaatc caacgctatc aagaccgttt aggacagttg
    17461 gacaagctct taggtagcca aatggcgtta gtttatgacg ccaaggttgc tgaggccaag
    17521 cgactttcgg aagctttgct catgttggat actagccgaa tcgtggcgcg tggttatgct
    17581 attgtcaaaa aagaagagtc cgttgtagat tcggttgaga gtttgaagaa aaaagaccaa
    17641 gtaacgcttt tgatgcgaga tggtcaagta gaattagagg ttaaagatgt caaaacaaaa
    17701 gaaatttgag gaaaatctag cagaactgga aaccattgtc caaagtttgg aaaatggtga
    17761 aattgctctg gaagatgcga ttactgcctt tcaaaagggc atggtcttgt caaaagagct
    17821 ccaagctacg ctggacaagg ctgaaaagac cttggtcaag gtcatgcaag aagacggaac
    17881 agaaagtgat tttgaatgaa aaagcaagaa aaattagctc ttgtcgagtc ggctttggaa
    17941 gatttttatg gagaccagca gtttgcctct agtttacggg agtctgttct ctattctatt
    18001 catgctggtg gcaagcgtat tcggcctttt ctcttgttag aagttctgga agccttgcag
    18061 gttgccatca aacctgctca cgcgcaggta gctactgcct tggagatgat tcatacaggg
    18121 agcttgattc acgatgacct tcctgctatg gatgatgacg attatcgaag agggcggtta
    18181 accaatcaca agaaattcgg tgaagctatg gccattttgg ctggagatgc cttattctta
    18241 gacccatatg ccttgattgc gcaggcagat ttgccaagtc agatcaaggt ggacttgatt
    18301 gccaacttat cccttgcttc aggtagtctg ggtatggtgg cagggcaagt tttggatatg
    18361 gagggcgaac accagcactt gtctctggaa gaacttcaga ctattcatgc caataagact
    18421 gggaagttac tagcctatcc cttccaagcg gcagctatta tagctgaatt gtcacctgaa
    18481 atgcaggtga agctgaaaac tgtgggtgaa ttgattggac ttgcttttca agtcagagat
    18541 gatgtactgg atgtgacagc tagttttgag gaaatcggca agacacctca aaaggatctg
    18601 caggcagaaa aatcaaccta tcctgccttg ttgggcttgg aagagtccat tgccttttgt
    18661 aaccaaaccc tggatcaagc taatgaaaaa ttagaagaaa ttgcccagca gattcccttt
    18721 gaaacagaat cgattgtaag tgtagtagaa agtttgagaa tcaatggcta aggaaagagt
    18781 ggatgtacta gcttataaac aggggttgtt tgaaacgaga gagcaggcca agcgaggtgt
    18841 gatggctggc ctagtcgtag cagtccttaa tggagaacgg tttgacaagc caggagagaa
    18901 aattccagat gacaccgaat taaaactcaa gggggagaaa ctcaagtatg tcagccgtgg
    18961 tggtttgaaa ctggaaaagg ccttgcaggt ctttgatttg tcggtggatg gcgcgactac
    19021 gattgatatc ggggcctcta ctggaggttt taccgatgtc atgctacaga atagtgccaa
    19081 gttggtcttt gcagtcgatg ttggtaccaa tcagttggct tggaaattac gccaagaccc
    19141 acgagttgtc agcatggagc agttcaattt ccgctatgct gaaaagactg atttcgagca
    19201 ggagccgagc tttgccagta ttgatgtgag tttcatttcc cttagtctga ttttgccagc
    19261 cttgcaccgt gtcttggctg atcaaggtca ggtggtagca cttgtcaaac ctcagtttga
    19321 ggcaggacgt gagcagattg ggaaaaatgg aattattcga gatgctaagg ttcatcagaa
    19381 tgtccttgaa tctgtaacag ctatggcagt agaggtaggt ttttcagtcc ttggcttgga
    19441 cttttctccc atccaaggtg gacatggaaa tattgaattt ttagcgtatt tgaaaaaaga
    19501 aaagtcagca agcaatcaga ttcttgctga gattaaagaa gcagtagaga gggcgcatag
    19561 tcaatttaaa aatgaataaa aaagagagac ttgaaaaaat tagaagattg gtgacagatt
    19621 atcaaatcgg cacgcaagaa gaaattgtag aacatttgaa agaagcaggt atcactgcca
    19681 ctcaggcgac ggtatcccga gatatcaaag agttaggtat tgtcaaaatt cctttgagag
    19741 acaacaccta tgtctacgaa ttaccaaaat caatcgtaaa aagtctgcaa ctggctgaag
    19801 acaatatcga atcggctgaa ttgatggata agatgatcaa tctccaagtt attccaggaa
    19861 atacggcttt tgtaaaagct cagttaatcg agacttttgc agacaagatt tttagctgtt
    19921 tgactgatga tagctcgatt ttagtcattg ccagaagtgg aagtctagca gaggaaatct
    19981 ttgaacaagt aaaaaattgg taggtctata tgttacttga aatttcgata aaaaactttg
    20041 ccattattga ggctatttcc ctcaattttg aaaaggggat gactgtcctg actggtgaaa
    20101 cgggtgcagg gaagtcgatt atcattgatg ccatgaatat gatgttggga gctcgtgcga
    20161 cgacagatgt tattcgtcat ggtgcaccaa aggcagagat tgaggggctt ttctcagttg
    20221 agaatagtcg tcttttacag gaaatttttg ataagcaagg tttagaatta ggtgatgaaa
    20281 ttatcatccg tcgggaaatc ttgcaaaatg gtcgtagtat cagccgtgta aatggtcaga
    20341 tggttaatct gtctgttttg cgagctattg ggcaacatct tgtagatatt catggtcagc
    20401 atgaccatga ggagttaatg cgtccccaac tgcatatcca gatgttggat gaatttggtg
    20461 atgccgcttt ttgggacttg aaagaaacct atcaaacgag ttttgatgcc tatcggaaaa
    20521 tgcgcaagca ggttctggaa gtcaagaaaa accaacagga acacaaggca cgtatcgaaa
    20581 tgttggaatt tcaaatggca gagattgagg cagcaaactt gcaggctgga gaagacttgg
    20641 ctctcaatca agagcgagat aaactcctca accacaaaaa tattgcggat acactgacca
    20701 atgcctacag tatgttggac aatgaagatt tttcaagtct ggccaatgtt cgttcagcta
    20761 tgaatgacat ggaaagtgtc gaagagtatg atcctgaata ccgtgaaatt tcaagctatc
    20821 tgtctgagac ctactatgtt ttagaagaca ttagcaaacg tttggaagct atcattgagg
    20881 accttgattt tgatggcaat cgcctgatgc aggttgagaa tcgtttggac ctccttcata
    20941 ctattactcg taagtatggt gggactgttg atgatgtttt gctttatttt gccaagatta
    21001 cggaagaata caatctcttg acaggcaata atctttcgtc tgaggacatg gaagcagagc
    21061 ttaagaagtt ggaagtcaat cttgtcaatt tggcaggtca acttgcttct gctcgtcata
    21121 atttggctca gcaactcgaa gctgagatta aacaagaact gcaagatctt tatatggaaa
    21181 aagcccagtt tcaggttcgt tttagtaagg gaaaattcag tcgtgaggga aataaaatgg
    21241 ttgagtttta tatttcaacc aaccctggag aagactttaa acccttggtt aaggttgctt
    21301 ctggagggga attatctcgt ctcatgttag ccattaagtc tgccttttca cgtaaagaag
    21361 gcaagactag cattgtcttt gatgaggtgg atacgggagt ttcaggtcgt gttgctcaag
    21421 ctattgctca gaaaattcat aaaattggtc agcatggtca ggttttggct atctcccatt
    21481 tgccacaagt aattgcgatt gcagattatc aattctttat tgagaagatt agtaatgacc
    21541 attcaacggt ttcgactgtt cgtctcttga cggtcgaaga gcgagtggag gaagttgcca
    21601 agatgttggc aggtgatgat gtgacagaag cagccctgac gcaagcaaga gaattgttga
    21661 gaaacaggga gaaataagat gacagattat tatgtaattg gagatgttca cggaaaagct
    21721 gggatgctgg aagaccttct caaaacctgg gatggtcagc cccagttgct ctttctaggt
    21781 gatttgattg acagaggtga ggatagtcac cgtgttcttg aaatggtcaa ggacttggtg
    21841 gacaatcaag gggctatctg tttgtccgga aaccacgagt atatgttttt gacttggcta
    21901 gatgacccag aagaaagtta tgaccattat agtcgcaatg gtggagatac aaccattaac
    21961 tctatcctag gtcgtccctt ggatgcacca gttgatggag tagaagatgc caagcgggtt
    22021 gccgctgaag cgtcagactt ggtcgaattc attcgtcaaa tgccatttgt agtagagaca
    22081 gacaagtata tatttgttca cgcaggtatt gatttgactt tggacgactg gcatgaaaca
    22141 acagattata aaaaagtatg gcttagaaaa ccattccacg gagctgaaaa tcatactgga
    22201 aaaaccattg tcttcggtca tacaccggtc tatggtttgt tacagcaaga acgcggtaca
    22261 tctgagcttt ggactacaga agatggcaag attggaatgg atggaggagc tgtttatggt
    22321 ggtgtccttc acgggattgt ctttacagac caaggaatga cagaacacca ctttatcgaa
    22381 aatgacggct ttgtcgctga agattagtac tcctagcagg gtatggtctt gtcaaaatat
    22441 caaaaacaat ttataataaa tagataccct gaaaggaaga gaatcatgaa cttagaagaa
    22501 ttgaaaaaac gacaggggaa gatccgtaac ttctctatta tcgcccatat tgaccacggg
    22561 aaatcaactc tagcagaccg cattttggaa aaaacagaga cggtttcaag tcgtgaaatg
    22621 caggcccagc ttttggatag catggatcta gagcgggaac gtggaattac tattaagttg
    22681 aatgccatcg agttgaatta cactgcaaaa gatggggaaa cttatatttt ccacttgatt
    22741 gacacaccag ggcacgttga ctttacctat gaagtttcac gttcgctagc tgcctgtgag
    22801 ggtgctattt tggtggtcga tgcggctcaa ggaattgagg ctcaaactct tgccaacgtt
    22861 tatctggctt tggataatga tttggaaatc atgcctatca ttaataaaat tgacctgccg
    22921 gctgcagatc cggagcgcgt gcgtacagag attgaagatg tgattggttt ggatgccagt
    22981 gaagcagttt tggcttctgc caaggctggt attgggattg aagaaatcct cgagcaaatt
    23041 gtagaaaaag taccagcacc aacgggtgat gtgacggcgc cacttaaggc cttgattttc
    23101 gactctgttt acgatgctta ccgtggggtt atcctccaag tgcgtgtcat ggacggagtg
    23161 gtcaaacctg gtgataagat tcagctcatg agcaatagta agacctttga tgtggccgaa
    23221 gtcggtattt ttacaccaaa agcggttggt cgtgatttcc ttgcgactgg tgatgttggt
    23281 tacattgcgg cgtctatcaa gacggttcag gatactcgtg tgggtgatac cgttaccttg
    23341 gcaaccaatc ctgcggcaga accattacat ggttataagc agatgaatcc tatggtcttt
    23401 gcgggtctct acccaatcga atcaaacaag tacaatgacc tgcgtgaagc gcttgaaaaa
    23461 ttgcaactga atgatgctag tcttcagttt gaaccagaaa catctcaggc acttggattt
    23521 ggtttccgtt gtggatttct tggacttctc catatggatg ttattcagga acgtttagag
    23581 cgtgagttca atattgacct catcatgaca gctccgtctg ttatttacaa agttaatttg
    23641 accgacggtg agtctatgga tgtgtctaac ccatctgagt ttccagaccc aactaagatt
    23701 gcgaccattg aagagcctta tgtcaaggcg caaatcatgg taccacagga gttcgtcgga
    23761 gcagtaatgg agctagctca gcgtaagcgt ggggactttg tgactatgga ctatattgat
    23821 gataaccgtg tcaatgttat ctatcaaatt cctcttgctg aaattgtctt tgacttcttt
    23881 gataaactta agtcttcgac acgtggttat gcaagctttg actacgaatt gtcagaatat
    23941 cgcccatcta agctggtgaa aatggatatc cttctcaatg gagataaggt ggatgccctc
    24001 agctttatcg ttcacaagga ctttgcctac gaacgtggga aactcatcgt tgataaactc
    24061 aagaaaatca tccctcgcca acaatttgaa gttccaatcc aagcggctat tggacacaag
    24121 attgtcgctc gtactgatat caaggccctt cgtaagaacg tgcttgctaa atgttatggt
    24181 ggtgacgttt ctcgtaagcg taaactcctt gaaaaacaaa aagctggtaa gaaacgcatg
    24241 aaatccatcg gatcagttga agttccgcaa gaagccttcc tcagcgtctt gagtatggat
    24301 gaagaataag ttatcagaaa tgcctttcct tgttcacagg aaatttatat aaaaatcaat
    24361 agtaaagcag gcttagatgg tctgcttttt tagtttttat actcttcgaa aatctcttca
    24421 aaccacgtca gcgtcgcctt accgtatgta tggttactga cttcgtcagt ttcatctaca
    24481 acctcagaac catgttttga gctgacttcg tcagtttcat ctacaacctc agaaccatgt
    24541 tttgagctga cttcgtcagt ttcatctaca acctcaaaat catgttttga gctgacttcg
    24601 tcagtttcat ctacaacctc aaaatcatgt tttgagctga cttcgtcagt cttatctaca
    24661 acctcaaaac tgtgttttga gtaacctgcg gctagcttcc tagtttgctc tttgattttc
    24721 attgagtatt agaacagaaa aatgcttgga gtatttgttt gtgtgtttat ttttatataa
    24781 caaactataa acaaaacaaa aatataaaaa aagagacaaa aaagaataga aagtaattaa
    24841 caacgatttc atatagtgtt atacttatag cataaagtta atggaaagaa gggaaaacct
    24901 tatggtatta gattatttct ttgacaaaaa ccttgtgttt tgcttagaag cggataatca
    24961 agaacaactc tttgatcagg tagcaagctt gttggaagaa cgagaaattg tcactccaac
    25021 ttatcgtgaa gccttgatca cgcgtgaaaa gtcatttcca actggtttag atatggaatt
    25081 tctaggaaag gacttgccaa atgtagcgat tcctcacaca gatattgttc ataatctagc
    25141 tgaaaaagtg gtggttgttc gattagaaaa accagtaact tttcacaata tgatagctcc
    25201 tgataaggaa gtagaagtat ccctactctt ctttatcatt aacaattcaa gttcaagtca
    25261 aacaaatatt ctggctcagt tgatggactt t
//
LOCUS       DBERXF010000032        25212 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.32, whole genome shotgun sequence.
ACCESSION   DBERXF010000032 DBERXF010000000
VERSION     DBERXF010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25212
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.32"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(123..1793)
                     /locus_tag="ACL8JK_001468"
     CDS             complement(123..1793)
                     /locus_tag="ACL8JK_001468"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGS1786334.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            2023..2712
                     /gene="coaB"
                     /locus_tag="ACL8JK_001469"
     CDS             2023..2712
                     /gene="coaB"
                     /locus_tag="ACL8JK_001469"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGS1786335.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2724..3275
                     /gene="coaC"
                     /locus_tag="ACL8JK_001470"
     CDS             2724..3275
                     /gene="coaC"
                     /locus_tag="ACL8JK_001470"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGS1786336.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            3259..3822
                     /locus_tag="ACL8JK_001471"
     CDS             3259..3822
                     /locus_tag="ACL8JK_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS1786337.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            4104..4631
                     /locus_tag="ACL8JK_001472"
     CDS             4104..4631
                     /locus_tag="ACL8JK_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS1786338.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            4643..5158
                     /locus_tag="ACL8JK_001473"
     CDS             4643..5158
                     /locus_tag="ACL8JK_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGS1786339.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(5155..5622)
                     /locus_tag="ACL8JK_001474"
     CDS             complement(5155..5622)
                     /locus_tag="ACL8JK_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGS1786340.1"
                     /translation="MFRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(5696..6184)
                     /locus_tag="ACL8JK_001475"
     CDS             complement(5696..6184)
                     /locus_tag="ACL8JK_001475"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1786341.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            complement(6150..6713)
                     /locus_tag="ACL8JK_001476"
     CDS             complement(6150..6713)
                     /locus_tag="ACL8JK_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGS1786342.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            complement(6723..8711)
                     /gene="uvrB"
                     /locus_tag="ACL8JK_001477"
     CDS             complement(6723..8711)
                     /gene="uvrB"
                     /locus_tag="ACL8JK_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGS1786343.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            complement(8788..9741)
                     /locus_tag="ACL8JK_001478"
     CDS             complement(8788..9741)
                     /locus_tag="ACL8JK_001478"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGS1786344.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            9914..12079
                     /locus_tag="ACL8JK_001479"
     CDS             9914..12079
                     /locus_tag="ACL8JK_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGS1786345.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            12079..12819
                     /locus_tag="ACL8JK_001480"
     CDS             12079..12819
                     /locus_tag="ACL8JK_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1786346.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            12968..14455
                     /gene="zwf"
                     /locus_tag="ACL8JK_001481"
     CDS             12968..14455
                     /gene="zwf"
                     /locus_tag="ACL8JK_001481"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGS1786347.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(14501..15778)
                     /gene="ftsY"
                     /locus_tag="ACL8JK_001482"
     CDS             complement(14501..15778)
                     /gene="ftsY"
                     /locus_tag="ACL8JK_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGS1786348.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEPERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(15782..16600)
                     /locus_tag="ACL8JK_001483"
     CDS             complement(15782..16600)
                     /locus_tag="ACL8JK_001483"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS1786349.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPIKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            complement(16600..17394)
                     /locus_tag="ACL8JK_001484"
     CDS             complement(16600..17394)
                     /locus_tag="ACL8JK_001484"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS1786350.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            complement(17391..20930)
                     /gene="smc"
                     /locus_tag="ACL8JK_001485"
     CDS             complement(17391..20930)
                     /gene="smc"
                     /locus_tag="ACL8JK_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGS1786351.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKYDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKASQQKDELETAKVQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRVGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            complement(20921..21619)
                     /gene="rnc"
                     /locus_tag="ACL8JK_001486"
     CDS             complement(20921..21619)
                     /gene="rnc"
                     /locus_tag="ACL8JK_001486"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGS1786352.1"
                     /translation="MKELQTVLKNHFEIEFADKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            complement(21802..21873)
                     /locus_tag="ACL8JK_001487"
     tRNA            complement(21802..21873)
                     /locus_tag="ACL8JK_001487"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21838..21840),aa:Arg,seq:ccg)
     gene            complement(21937..22923)
                     /locus_tag="ACL8JK_001488"
     CDS             complement(21937..22923)
                     /locus_tag="ACL8JK_001488"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGS1786353.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            complement(23089..24405)
                     /locus_tag="ACL8JK_001489"
     CDS             complement(23089..24405)
                     /locus_tag="ACL8JK_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HGS1786354.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYQRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRRNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEMGNL
                     AGYGAQLKKWSIRIPQNASFYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            complement(24392..>25212)
                     /locus_tag="ACL8JK_001490"
     CDS             complement(24392..>25212)
                     /locus_tag="ACL8JK_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS1786355.1"
                     /translation="VNSRQNLSVNYDSGVPGWSLPSKYVYELYKDKNYNKQEYYKSGG
                     KTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEINRGEISKIFGELFFSIDPDYRGE
                     KGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDRSVDTFDFAMRRRFRFVEVTAEGQ
                     VGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSHYHIGPSYFLKLKDVDFDYELLWS
                     DYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQKDQAVADDNEGDENDDADY"
BASE COUNT         7341 a         5634 c         4537 g         7700 t
ORIGIN      
        1 aagctgacgt agtttgaaga gattttcgaa gagtataaat cttattgatg aactgcttgc
       61 agtctgagaa aaaatgagct tggatattat ttccaaactc acttaaagtc aatttcaatc
      121 cactagaaca agcctagtac agttccatcg ctttcaacat ccatgttgag agctgctgga
      181 cgttttggaa gacctggcat ggtcataaca tcaccagtta aggcaacgat gaagcctgca
      241 cctaattttg gtaccaattc acgaatggta atttcaaagt tttctggtgc tccaagcgca
      301 tttggattgt ctgagaaact gtattgagtt ttagccatac agattggcaa tttgtcccaa
      361 ccgttttgaa cgatttgagc aatttgtgtt tgagctttct tctcaaagtt cactttgcta
      421 ccacgataga tttcagtgac aattttttca atcttttctt ggacagaaag gtcgttatca
      481 tacaaacgtt tatagttagc tggattttca gcaattgtct taacaactgt ttcggcaagt
      541 gctactccac cttctgctcc atcagcccag acactagcca attcaactgg tacatcgatt
      601 gaggcacaga gttcttttaa gactgcaatt tcagcttctg tatcagatac aaattcgtta
      661 atagctacaa ctgctggaat accgaactta cggatatttt caacgtggcg tttcaagtta
      721 gcaaaacctg cacgaactgc ctctacattt tcttcagtca gagcgtcttt agccacacca
      781 ccattcatct taagggcacg aagggttgcg acaataacaa ctgcatctgg agatgttggc
      841 aagtttggtg tcttgatatc aaggaatttc tcagcaccaa ggtccgcacc aaaaccagct
      901 tcagtaacag tgtaatcagc caagtgaagg gctgttgtcg tcgccaaaac agagttacag
      961 ccatgagcga tattggcaaa tggaccaccg tgtacaaagg caggtgtacc gtaaattgtc
     1021 tgaaccaagt ttggcttaat agcatccttc aaaatcaaag ccaaggcacc ctcaacctgc
     1081 aaatcaccta cagaaacagg cgtacggtca tagcgataac caataacgat attcgccaaa
     1141 cgacgtttca agtcctcgat gtccgttgcc aagcaaagaa ttgccatgat ttctgaagca
     1201 actgtaatat caaaaccgtc ctcacgtgga ataccgttta gaggaccacc aagaccaaca
     1261 gtcacatggc ggagcgcacg gtcgttcaag tccacaacgc gtttccagag gatacgacgt
     1321 tgatcaattc ccagctcatt cccttggtgc aagtggttgt caatcaaggc agaaagggca
     1381 ttgttggcag ttgtaatagc atgcatatct ccagtaaagt ggaggttgat gtcttccatt
     1441 ggcagaactt gtgcataccc accaccagca gcaccaccct tgatccccat gactggacca
     1501 agagacggtt cgcggatagc aatcatggtt tttttgccaa tcttgttcaa ggcatccgca
     1561 agaccaatgg taagcgtcga ctttccttca cctgcaggtg ttgggttgat ggcagtaacc
     1621 aagatcaatt taccgactgg attgctctca actgcacgaa ttttatcaaa gctgagttta
     1681 gccttgtact ttccgtacaa ctccaaatcg tcgtaagaaa taccaagttt ctctacaaca
     1741 tcaacaattg gcttcaactc aatactctgt gcgatttcaa tatctgtttt cattcaaaat
     1801 tcctctaacc tcttatatga taattcatta tatcacaaaa caagattttt aacatcctaa
     1861 aactctctaa acgttcgtaa atatctctgt ttttaaggct tttagagtcc tttcttaaat
     1921 tttatatggc tttatagttt gaaactatag taaatcttcg tttttaccaa aaatttatca
     1981 ctttcatttt acttaccgct tatttttgtg tacaatagtg ctatgaaaat tttagttaca
     2041 tcgggcggta ccagtgaagc tatcgatagc gtccgctcta tcactaacca ttctacaggt
     2101 cacttgggga aaattatcac agagactttg ctttctgcag ggcatgaagt ttgtttaatt
     2161 acgacaaaac gagctctgaa gccagagcct catcctaacc taagtattcg agaaattacc
     2221 aataccaagg accttctaat agaaatgcaa gaacgtgttc aggattatca ggtcttgatc
     2281 cactcaatgg ctgtttctga ctacactcct gtttatatga cagggcttga ggaagttcag
     2341 gctagctcca atctaaaaga atttttaagc aagcagaatc atcaggccaa gatttcttca
     2401 actgatgagg ttcaggtttt gttccttaaa aagacaccca aaatcatatc cctagtcaag
     2461 gaatggaatc ctactattca tctgattggt ttcaaactgc tggttgatgt taccgaagat
     2521 catctggttg acattgcacg aaaaagtctt atcaagaatc aagcagattt aatcatcgcg
     2581 aatgacctga ctcaaatttc agcaggtcag caccgagcta tatttgttga gaaaaatcag
     2641 cttcaaacag tccagactaa agaagaaatt gcagaactcc tccttgaaaa aattcaagcc
     2701 tatcattctt agaaaggaaa actatggcaa acattctctt ggctgtaacg ggttcaatcg
     2761 cctcttataa gtcggcagat ttagtcagtt ctctaaaaaa acaaggccat caagtcactg
     2821 tcttaatgac tcaggctgct acagagttta tccaaccttt gacactacag gtactctcac
     2881 agaatcctgt ccacttggat gtcatgaagg aaccctatcc tgatcaggtc aatcatatcg
     2941 aacttggaaa aaaagcagat ttatttatcg tggtacctgc aactgctaac actattgcaa
     3001 aactagctca cggatttgcg gacaacatgg taaccagtac agctctagcc ctaccaagtc
     3061 atattcccaa actaatagct cctgctatga atacaaaaat gtatgaccat ccagtaactc
     3121 agaataatct gaaaacatta gaaacctacg gctatcagct gattgctcct aaggaatctc
     3181 tactagcttg tggagaccac ggacgaggag ctttagctga cctcacaatt attttagaaa
     3241 gaataaagga aactatcgat gaaaaaacgc tctaatattg cacccattgc tatctttttt
     3301 gctaccatgc tcgtgataca ctttctgagc tcacttatct ttaacctttt tccatttcca
     3361 atcaaaccga ccattgttca tattcctgtc attattgcca gcattattta tggtccacga
     3421 gttggggtta cacttggatt tttgatggga ttacttagct tgacggttaa cacgattacg
     3481 attctaccga caagctacct cttctctccc ttcgtaccaa acggaaacat ctactcagct
     3541 atcattgcca tcgtcccacg tattttgatt ggtttaactc cttacttagt ctataaactg
     3601 atgaaaaaca agactggtct gattttagct ggagcccttg gttccttgac aaatactatc
     3661 tttgtccttg gaggaatctt cttcctattt ggaaatgttt ataatggaaa tatccaactt
     3721 cttctggcaa ccgttatctc aacaaattca attgctgaat tggtcatttc tgcaattcta
     3781 accctagcca ttgttccacg actacaaacc ttgaaaaaat aaaaacaatc tccgctttca
     3841 aacctgaagg tggagatttt gctctataca gtttcttttt aatgaaatct ttactatagt
     3901 aaaacgaaat aagaacagga caaatcgatc aggacagtca aatcgatttc taacaatgtt
     3961 ttagaagtag aggtggacta ttctagtttc aatctactat aacttttaac taaaaaatga
     4021 tctataaacc caagtaaatt cttgctttat tgtctggttt attgtaccat actagtgtat
     4081 atgcagttaa aaaggagatt cttgtgaata cacggaaaaa gacacaattt atgacaatga
     4141 cagccctttt aacggctatt gcgattttga ttccaattgt tatgcctttc aagattgtca
     4201 ttccacctgc ttcctatact ttggggagcc acatcgctat ttttatagcc atgttcttgt
     4261 cgcccttgat ggcagttttt gtcatcctag cctctagttt tggatttttg atggctggct
     4321 atcccatggt tatcgttttt cgggcttttt cccatatatc ttttggtgct ttaggagctc
     4381 tttacctaca aaaattcccc gataccctag ataaaccaaa atcttcctgg gttttcaatt
     4441 ttgttttggc tgttgttcat gcccttgctg aagtattagc ctgtgtcctt ttttacgcaa
     4501 cttcgggtac caatgtagaa aacatgttct atgttctatt tgtactagtt ggatttggca
     4561 caattatcca tagtatggta gactatacat tagcactagc tgtctataaa gtgcttcgaa
     4621 aacgccgtta aaaggaaaag ctatgacaaa agatcgcaaa caagccctgc tccaactctt
     4681 gaaagaagct cctaaagccc ttaatggcca aagtttggcg gaacattttc atgtcacacg
     4741 tcaggtcatt gtgcaggaca ttgcaatttt gagagccgat ggcgctccta tcctatccac
     4801 caatcgtggc tacatctata agcaaattga taccaatcct tatgttcaca aacttttcaa
     4861 agtgaaacat gaagttgaag aaatcggtca ggaactcctt gctattgtcg ataatggtgg
     4921 gcatgtccag aataccttga ttgaccatcc cgtttatgga gaaattgaaa ccttgcttaa
     4981 actgtcttgt cgcagagatg tgcaacattt tctagaacaa gtcgagcatt ctgactttag
     5041 acctctatct gaattgacag atggcatcca ttaccaccta gtcgaagccg aaacacaaca
     5101 agacctccac tatatcgagg aggccttgga tcagctaggt tatttagtaa aagactagaa
     5161 gattttcttt tcccaatcgt cttctgtacg gcgaggatag aaaaactctg acttgtcggg
     5221 agcttccatc atttccatca atggtagcat atcataggcc agatttaagt ttggaatctg
     5281 gtctttttgc acccaagaaa cttctccctc ttctgaagat tgaagggtac cagagaactc
     5341 agtcgcctta taacaaatga caatatagcg cccacctgta tctagtggcc aatttttaat
     5401 gccgacaagt tgaggatttt ggatagtcaa ccctgtttct tcgtagattt cacgaatgac
     5461 agactccgca aaagcctcat cattttctac atgacctcca ggaaaggcat aaccagacca
     5521 gcgattgttt tcaggggcgc gatactgcat caccacgcgc tgagtttcga ggtcttcaat
     5581 cagacagata tttgttaaaa ttgttaattg ggaacggaac ataaatttac tcgctttcta
     5641 atttattaaa ttttcagact tactaccaga gatattatct tttacttttt taaaattatt
     5701 tagaatagaa caccattcgt ttttccttta taggctttcc aagttcaagt attttttctt
     5761 gtccatcaaa agtaaaaccc attttttgat agaaagcaat ggcgcgcttg ttatctttca
     5821 atacccataa gaaaatttca gaaaaatgat taagagcagt caaagctgct ttcattaact
     5881 tttgtgcgat accttttcca taatagtctt ttaaaacata taaagcaata atttcaccag
     5941 cttgaatagt ctcatcacga aagttaccat aactgataaa accaactacc ttcagatcac
     6001 ctatcgcaat caatgtattt tctggatact tttgactaaa gaatcgacat ctttctaatg
     6061 tcattgtctc ctgaaattct gcaggcaaaa ggtcatcata agcctctctc cacgtttgcc
     6121 agtgaacgag ggatttacct tctatctctt caggagtttc cattgatttg ataataaccg
     6181 tcatttattt tctcccagtc ttctctcaaa ataccatatt taatactatc aaaatattta
     6241 ccttgataat aacgaacttt tggaatatga gcttcttttt tcattcttaa tttttcagca
     6301 agtttcatca taccaagatt tcctgaccaa gttgtcaaac ccagatgctc caactccaag
     6361 taatcctgaa acgtcctatc tatccactgc aacatagcaa ctttcccaat accagtgttc
     6421 cagaattttt tatcataaat accaattccc aattccatcc atcttgtttc tttacatacc
     6481 caataacgcg aaacagtccc aactagttta tcatcaacaa aaataccaag gcgatttgag
     6541 ttgcttaaaa tggattctga tttttgtagt tcgaattctt taaaatttga aaaatactga
     6601 taatcatcat aatagggagc atcatactgt ttccaaactg gattaagctg tgaataagcc
     6661 atttcccata aagacatcaa atcttctttc tttaactttc ttaaataaat catactattc
     6721 ccctaatcca aggccttgac ttccaacatc atatcacgga tctgagccgc cagttcaaag
     6781 tcaagcactt cgacggcttc ttgcatttgt ttttctagtt tcttgacgag ttctttgcgc
     6841 tcttgtttgt tgaggctatt gatgtcgact tccttgtcct cttccttagc aactgccttg
     6901 gtcacggcaa tcaggtcacg gatttctttc ttgattgtct gtggtacgat accatgctct
     6961 tcattatagg ccatctgaat tttccgacgg cgggcagttt catcgatagc acgttgcata
     7021 gactgggtaa ccgtatctgc atacatgatg acatgacctt cactgttacg ggcggcacgc
     7081 ccaatggtct ggatgagtcc acgctcgtta cgaaggaaac cttccttgtc agcatcgaga
     7141 atggcaacca agctaacctc aggaacgtca atcccttcac gaaggagatt gattccaacc
     7201 aagacatcaa agacacccaa gcggagatca cggataatct ccgtccgttc caaggtcttg
     7261 atatccgagt gcatgtactt gaccttgatg cccatttcct tgaaatagtc ggtcaagtcc
     7321 tctgccattt tcttggtcaa ggtggtgata aaggttcgtt cattcttttc aacacgggca
     7381 ttgatttcac ctaagagatc atcaatctgt cccatagtcg gacggacttc cacctcagga
     7441 tccaaaagcc ctgtcggtcg aatgatttgc tcaatcaccg tctcagtctg ttcattttca
     7501 tagtcaccag gtgtcgctga tacgtaaaca atctgatgca catggctttc aaactcctca
     7561 cgacggagag gacgattgtc caaggcagac ggtaaacgga aaccataatt tactagcatt
     7621 tccttacgcg aacggtctcc attgtacatg ccttttattt gtcccatagt catatgactc
     7681 tcgtcaatca taatcaaaaa atcatctggg aaaaagtcga gaagcgtata aggaggctca
     7741 ccttcactac gtccatccat gtggcgagaa taattttcaa ccccatttgt atagcccatc
     7801 tcgcgcagca tttcgatatc gtactctgtc cgttgtttca agcgctgggc ttcaagcaat
     7861 ttaccttcct tctcaaagac agctaactgc tcttctaatt ctgcttgaat cttagcaacg
     7921 gcaacttcca tatggtcgtc attggtcaca aagtgagtag ctgggaaaat cgccaaatga
     7981 tccacctctc ccaatacctg acctgtcaga gcctcaacct cacggatacg gtcaatttcg
     8041 tctccaaaaa attctactcg aaaggcatgt tcatctcggg aagctgggaa aatctctacc
     8101 acatccccac gaacgcgaaa tcttccgcgt tggaaatcaa tatcattacg ttcaaactga
     8161 atatcgacca agtcattcaa gagtttatca cgagaaatct ctagaccagg acggagacta
     8221 acgacactat cagcgtattc cttgggcgaa cccaaaccat agatacaaga gactgaggcc
     8281 acgacaataa catcattacg ctccaaaagg gctgaggtag ctgagtggcg aagcttgtca
     8341 atctcgtcat tgacagaact atccttctca atataggtat cgctagaagg gacataggcc
     8401 tctggctggt aataatcata gtaggatacg aaatactcaa ctgcattttc agggaaaaat
     8461 tccttaaact ccccatagag ctgaccagcc agagttttat tgtgggcaat aaccagagtt
     8521 ggtttattga ctttagaaat gacctgactc atagtatagg tcttccctgt tccagtcgcc
     8581 cccatcagaa tctgagcttt ttctcccccc tcaatgttat ccaccaactg ctcgatagct
     8641 tggggttgat ctcctgatgg ttgatatttt gatactagtt taaattgatt atctgtaatg
     8701 tgattgatca taagaatcct ctctccatgt gctattccta ttttagcata cttatagtat
     8761 tttcacgaag aaaaggacgg accgaagtca catcctttca ttttctttct ttaatttatt
     8821 agcaagatag acaatcagca gtagtaatac cagacttgtc ataatggaac cttctatgcc
     8881 aaaagaacca cctgatagcc aatcttgatt gccttgtggt aaaaaggtca tcagagacgt
     8941 tcctgacggt tgaccactaa ctaaaatccc aaagagatta ccctgagcaa aattccaagc
     9001 accatgaata cctgcaacac cccaaactgt atcagttttg agaagataaa gagccatggc
     9061 aactccgaat aaaaagagat ttactagaga tagaggggtg aggccagaat tgcccatatg
     9121 aagcagggta aagaacaggc tagatataag aatagctagt tttagattgg ttcttgaggc
     9181 caattgagga agtagccaag cacgggccac cacttcttct gctgtcccct gtaaaatcca
     9241 aaatgggata gtaaagacga caaaggcaag agaataagga ttcaagtgaa tggattccaa
     9301 acgatattga cctaagacca ctaaacctaa caaggtcaga agaaaaagtg ccaagcctag
     9361 actaaatcct ttcagaagat tgctgaggaa attctctcta taaaatccca aggttcgaat
     9421 aggtcttttc tcaacttttc ttgtccatct gaacacagtg ttaagaataa aaccaaaggc
     9481 cagtaatcct aaaattaaac gaaagtcact tgttttatcc gtcaagctct gatgcaaggt
     9541 ctgcaagtag gttgcaagat tttgaccagc ctctccaaaa tttctagcaa gtccgatgag
     9601 agctaacaag ccaataccat acaaagtaaa agccacaaac tctcctatga agacaaaaac
     9661 aaaggctaac aaggggcttg tgtaaatgtt taaactcatt tttgaagctt ggaagtcttt
     9721 aaatattctt ttgttcttca tatccccgtc ctcttttctt ctatatatac tattattata
     9781 gcacttttta atagcaattc aagaaagaaa aggaaaaatc aatgttatat tttctgacac
     9841 gaaaaatata acaatttgcc tttttttact ttttctgata taatgagaga atattcggaa
     9901 aaggagacta aaaatgaaga aaaaatttct agcatttttg ctaattttat tcccaatttt
     9961 ctcattaggt attgccaaag cagaaacgat taagattgtt tctgataccg cctatgcacc
    10021 ttttgagttt aaagattcag atcaaactta taaaggaatt gatgttgaca ttattaacaa
    10081 agtcgctgag attaaaggct ggaacattca gatgtcctat cctggatttg acgcagcagt
    10141 caatgcggtt caagctgggc aagccgacgc tatcatggca gggatgacaa agactaaaga
    10201 acgtgaaaaa gtcttcacca tgtctgatac ttactatgat acaaaagttg tcattgctac
    10261 tacaaagtca cacaaaatta gcaagtacga ccaattaact ggcaaaaccg ttggtgttaa
    10321 aaacggaact gccgctcaac gtttccttga aacaatcaaa gataaatatg gctttactat
    10381 taaaacattt gacactggtg atttaatgaa caacagcttg agtgctggtg ccatcgatgc
    10441 catgatggat gacaaacctg ttatcgaata tgccattaac caaggtcaag acctccatat
    10501 tgaaatggat ggtgaagctg taggaagttt tgctttcggt gtgaaaaaag gaagtaaata
    10561 cgagcacctg gttactgaat ttaaccaagc cttgtctgaa atgaaaaaag atggtagtct
    10621 tgataaaatt atcaagaaat ggactgcttc atcatcttca gcagtgccaa ctacaactac
    10681 tctcgcagga ttaaaagcta ttcctgttaa ggctaaatat atcattgcca gcgattcttc
    10741 ttttgcccct tttgttttcc aaaattcaag caaccaatac actggtattg atatggaatt
    10801 gattaaggca atcgctaaag accaaggttt tgaaattgaa atcaccaacc ctggttttga
    10861 tgctgctatc agtgctgtcc aagctggtca agccgatggt atcatcgctg gtatgtctgt
    10921 cacagatgct cgtaaggcaa cttttgactt ctcagaatca tactacactg ctaataccat
    10981 tcttggtgtc aaagaatcaa gtaatattgc ttcttatgaa gatctaaaag gaaagacagt
    11041 cggtgttaaa aacggaactg cttctcaaac cttcctaaca gaaaatcaaa gcaaatacgg
    11101 ctacaaaatc aaaacctttg ctgatggttc ttcaatgtat gacagtttaa acactggtgc
    11161 cattgatgcc gttatggatg atgaacctgt tctcaaatat tctatcagcc aaggtcaaaa
    11221 attgaaaact ccaatctctg gaactccaat cggtgaaaca gcctttgccg ttaaaaaagg
    11281 agcaaatcca gaactgattg aaatgttcaa caacggactt gcaaacctta aagcaaacgg
    11341 tgaattccaa aagattcttg acaaatacct agctagcgaa tcttcaactg cttcaacaag
    11401 tactgttgac gaaacaacgc tctggggctt gcttcaaaac aactacaaac aactccttag
    11461 cggtcttggt atcactcttg ctctagctct tatctcattt gctattgcca ttgtcatcgg
    11521 aattatcttc ggtatgttta gcgttagccc atacaaatct cttcgcgtca tctctgagat
    11581 tttcgttgac gttattcgtg gtattccatt gatgattctt gcagccttca tcttctgggg
    11641 aattccaaac ttcatcgagt ctatcacagg ccaacaaagc ccaattaacg actttgtagc
    11701 tggaaccatt gccctctcac tcaatgcggc tgcttatatc gctgaaatcg ttcgtggtgg
    11761 tattcaggcc gttccagttg gccaaatgga agccagccga agcttgggta tctcttatgg
    11821 aaaaaccatg cgtaagatta tcttgccaca agcaactaaa ttgatgttgc caaactttgt
    11881 caaccaattc gttatcgctc ttaaagatac aactatcgta tctgctatcg gtttggttga
    11941 actcttccaa actggtaaga ttatcattgc tcgtaactac caaagtttca agatgtatgc
    12001 aatccttgct atcttctatc ttgtaattat cacacttttg actagactag cgaaacgctt
    12061 agaaaagagg attcgttaat ggcaaaatta aaaattgatg taaatgattt acacaagcac
    12121 tatggaaaaa atgaagtcct aaaaggaatt acgactaagt tctatgaagg agatgttgtt
    12181 tgtatcatcg gtccttcagg ttctggtaag tcaactttcc tccgtagcct caatctttta
    12241 gaagaagtca ctagcggtca catcactgtg aacggctatg atttaactga aaaaacaacc
    12301 aatgttgacc acgtccgtga aaatatcggc atggtattcc aacacttcaa cctcttccct
    12361 catatgtctg tattggacaa catcaccttt gctcctattg agcacaagtt gatgactaag
    12421 gaagaagctg agaaattggg aatggagttg cttgaaaagg ttggactagc agataaagct
    12481 aatgccaatc cagatagcct atcaggtggt caaaaacaac gtgtggccat agctcgtggc
    12541 ctagcaatga atccagacat catgctcttc gatgaaccaa cttctgccct tgaccctgag
    12601 atggttggag acgtacttaa cgttatgaag gaattggctg agcaaggcat gaccatgatt
    12661 atcgtaaccc atgagatggg atttgctcgt caggttgcca accgcgttat ctttactgca
    12721 gatggcgagt tccttgaaga cggaacacct gaccaaatct ttgataaccc acaacaccct
    12781 cgtctgaaag agttcttaga taaggtctta aacgtctaaa ctcaaactgt aaggatttcc
    12841 ttgcagtttt tctacctcgt attggaattt ttgatttttc ggaaaattat gttagaatta
    12901 agtttatgaa atgaggtttc ctcataccta gcaagactag gaataaaaat agaaattagg
    12961 tagctagatg tcatctaagg ttattgttac aattttcggt gcgagtggag acctggctaa
    13021 acgcaagctc tacccttccc tttttagact atataaatcc ggcaatcttt ccaagcactt
    13081 tgccgttatt ggaactgccc gtagaccttg gagtaaggaa tattttgaat ctgtagttgt
    13141 cgagtccatc cttgatttgg cagatagtac cgagcaagcc caagaatttg ctagccactt
    13201 ctactatcaa agccatgatg tcaatgattc ggaacattat attgctttgc gtcaattaca
    13261 agctgagctt aatgaaaaat accaagctga acacaataag ctcttcttct tgtctatggc
    13321 acctcagttc tttggaacca ttgccaaaca cctcaaatct gaaaacattg tcgatggcaa
    13381 aggttttgag cgcttgatcg ttgaaaaacc atttggtaca gattacgcaa ctgcaaacaa
    13441 gttgaatgac gaactcctag caacatttga cgaagaacaa attttccgta tcgaccatta
    13501 tcttggtaag gaaatgatcc aaagcatctt tgcagttcgc tttgcaaact tgatttttga
    13561 aaacgtttgg aacaaggatt ttatcgacaa tgttcaaatt acctttgcgg agcgcttggg
    13621 tgtagaagaa cgtggtggct actatgacca atccggtgcc ctccgtgaca tggtccaaaa
    13681 ccacactcta caacttcttt cgctcctcgc catggacaaa ccagcaagct tcacaaaaga
    13741 cgagattcgt gctgaaaaga ttaaggtctt taaaaacctc tatcatccaa ctgatgaaga
    13801 actcaaagaa cactttatcc gtgggcaata ccgctctggt aagattgatg gcatgaaata
    13861 catctcttat cgtagcgagc caaatgtgaa tccagaatca acaactgaaa cctttacatc
    13921 tggtgccttc tttgtagaca gcgatcgatt ccgtggtgtt cctttctttt tccgtacagg
    13981 taaacgactg actgaaaaag gaactcatgt caacatcgtc tttaaacaaa tggattctat
    14041 ctttggagaa ccacttgctc caaatatttt gaccatctat attcaaccaa cagaaggctt
    14101 ctctcttagc ctaaatggga agcaagtagg agaagaattt aacttggctc ctaactcact
    14161 tgattaccgt acagatgcga ctgcaactgg tgcttctcca gaaccatacg aaaaattgat
    14221 ttatgatgtc ctaaataaca actcaactaa ctttagccac tgggatgaag tttgtgcgtc
    14281 atggaagttg attgaccgta ttgaaaagct ctgggctgaa aatggtgccc cacttcatga
    14341 ctataaagct ggaagcatgg gacctcaagc cagctttgac ctacttgaaa aattcggtgc
    14401 caaatggact tggcaaccag atatcaccta tcgtcaagat ggtcgcttag aataaaaaaa
    14461 tttcctgcaa gtttatgcct tgcaggattt ttgcttctga ttagattaaa ccttccaaga
    14521 gacctttcat aaagttttct gagttaaact ctccaatatc atcgattttt tcaccaaaac
    14581 caatcaattt tacaggaata ttgagttctt cacgaatggc tagaaccaca cctcctcgag
    14641 cagttccatc aatcttagtc aaaacaattc ccgttaaagg tgtgattttc gaaaattctt
    14701 tggcctgtac tagggcattt tgacctgttg atgcatcaag tgccaagaag gtttcatgtg
    14761 gtgcttctgg cacaacacgt ttgataatac gaccaatctt ttccaactca gccataaggt
    14821 tatccttatt ttgcagacga ccagcagtat caatcatgag aatatcgata ccttcagcca
    14881 cggcacgttc cataccatca aagaccacgc tggctggatc agctttttca ggtccagtta
    14941 ctactggaac atctactcgt cggccccatt cagctagctg agctactgca cccgcacgga
    15001 aggtatctgc tgcaaccagc atgaccttct taccagcttg tttgtagcgg tgggctagtt
    15061 ttccgataga agttgttttc ccaacaccat tcacaccaac aaagagcata actgtcaagt
    15121 tatcttggaa gtggatgctt tcatcgtagc taccatcctt ttcataaagc tcaaccaatt
    15181 tctcaatgat gacacgacga agtgcatcag gtttcttggc attttcaagc ttggcttcgt
    15241 aacgtagttc ctccgttaag ttagaagcga cttggacacc aacatcactc ataatcagca
    15301 gttcttccag ttcctcgaaa aattcttcgt caacagagcg gaagttagca aagaaggcat
    15361 tcaagcgggc accgaaacct gtacgagttt tcttaagact gcggtcatat ttttcctgaa
    15421 cggtttcttc tgcttgaggc ctttctggtt caagaacttc agaattattt tcttctatag
    15481 tctctagaaa ctcagtattc ccttcttctg agtgtggaaa ttcttcgact tctttttgag
    15541 aaacttctac aactggctct aaatccagac tttcttcaac tgtgtcttgg atttcctctt
    15601 cttggaacac agcttgttca acaatttcaa cctctgcttc ttcctgagaa acttcctcaa
    15661 cttctgtgaa ggtaggatca acatcttcag acaaatcaag attttccaga gcttctttta
    15721 caacttcttc gattttaggt tcttcttttt ttccgaatag acggtcaaac aatcccatat
    15781 cttagttctc ctttagcaca tattcttcga tagcccaggc gacagcttcc tcatcgttgg
    15841 tcatcggcgt cactacattt gcggctgcct ttacttcagg aacagcgttt tgcatagcaa
    15901 caccaagacc tgcccattca atcatagaga ggtcattggc ctcgtcacca caagccatca
    15961 cttgactttg gtcgattcca agatggctga ttagttttgc caaacctgtt gctttatgaa
    16021 cattctttgg tgaccattct agcaacattt cacgtgattt aaagatttca tattggtcaa
    16081 acaattctgg agaaatcttc tgaatggctg catccaaggg ttcttgagca aaggcagtca
    16141 cgcatttgtt gtaggtcatt tgactagata agtcttcaaa gtccactgga acaaaggtca
    16201 aagctggatt gaatttggca taaagacttt cttggtccga ttggatttga taaactgttc
    16261 cttctgagat ggcatcaaga ggcagtgata atttctctgt ttcttcatac aaacgtgcca
    16321 catcatcata tgaaaagact gttttatcaa ggatttctcc tgtatttttc tgaactaatc
    16381 caccattaaa agtaatggta tactcatctt cctgaccgtc agtccctaac tcatggagaa
    16441 agaaatccat ggcttttatg ggacgaccag ttgtcaatac gaccttgata ccacgatcac
    16501 gcgcagcttt caaggtttcc ttggtacgat ccgtcagcct tttatcagta gtcagcaagg
    16561 tcccgtccaa gtccaatgca atcaatttta tatctgccat tataagccct ccatataagc
    16621 tataaccgac cgttccttat ggtgaccaat cacagtcttt gctaattcta aaatttcagg
    16681 tcgtgcattt tcaggagcta caggatgtcc cacaacctgc atcatatgta agtcattaag
    16741 attgtctcca aaagccatga cctgatccat tgtgatacca agttttttag ctaattcaac
    16801 aatagctaca cccttatcga catagtccag aacaatatca atagattcaa agccagttgt
    16861 catggcctta acaccaggga catgttcatt aacccaagct tcaccagctt ctagcgtttc
    16921 ttctgtgaag ttggttgtaa atttgaaaat gtcatctgtg atatcttcca aactcgctac
    16981 tttttggata ttttcattat aatgctgact cactttcaaa taggtctcat caaccgtatc
    17041 tagaacatat gaacccttct tacccgtcaa gagcagttta ttgatatcta cataaggtga
    17101 cgttttcagc ttttcaaaag ttgccagata aaagtcacga gacatagtcg cttcatacaa
    17161 gtcctgacct tgatactcta ccaaactgcc attttccgcg atgaaaataa tgtcatcacg
    17221 aacatcagca aataattttt ccagagacag aaatccccga cccgaagcca ccgcaaagta
    17281 aatccctttt tccttgtagg aagccaagag agacttgaga cgatccatat caaagcgtcc
    17341 attcccatct aggaaggttc cgtccatatc cgttgctact agtttaattg tcatccttca
    17401 atactttcta aatcttttaa cttaactgaa acaatctttg aaacacccga ttcttgcatg
    17461 gtcactccat agatggaatc agccgctgcc atggttccct tacggtgggt tacaacgata
    17521 aactggctgt ccttgtcaaa acggttgagg taatccccaa aacgtttaac attggcttca
    17581 tccagcgcag cttccacctc atccaagatg acaaaaggaa tggtcttgac acgaataatg
    17641 gagaaaagca aggcaagagc cgatagagct ttttcaccac cactcatgag gttaagcgac
    17701 tggattttct tacctggagg ttgaacagaa atctccacac cagctgttaa aaggtcgccc
    17761 tcagtcaata tcaagtctgc ctgacctccg ccaaacatct gcttgaaggt cactttaaag
    17821 gactcacgaa tagcttcaaa ggttgattta aagcgttcct tgacctcatc attcatctct
    17881 gtaatggttt caaggagcag atttttcgct gacaaaatat catctcgctg actatttaga
    17941 aagtccagac ggttgtgaac ttcttcgtac tggtcaatag cttccaagtt gacaggtccc
    18001 aatgagcgaa tagccttctc taaatcctgc acctcttgct ctgccagatt gaggttttcc
    18061 aattcatgtg ccttttctag tgcttcagta tagctaatct ggtactggtc tgttaattga
    18121 ttttgtagat ggcgcaagcg ctcgctgacc ttttctttct tggcttcagc acgtgtttgc
    18181 ttgcgaatcc actcctcatt ctgctggcga gcttgatcca agtgactggc aatatcatcc
    18241 agttgacctt ctatatcatc caactcaaac tgcttgcgaa tcaaaccttg ttggagattt
    18301 gttttctgag ttttggattc ttccgcctgt tgactgagca attctgtatc aaccttctca
    18361 agattgtcaa ctttttcttg gagcatgcgc tgaatttctt cttgttcgat attaagattg
    18421 tccaattcct tgcctaaacg ctcaatatca gctacttcat aacgtttttg cccttgcagt
    18481 tctgtcttaa gcaagcgagc ttgcgccacc tcttcctgca aattttgata gcgttcttgg
    18541 atggcgtttt tattagactt aatttcttca atctcagctt ccagattttg cttttcactg
    18601 gcgatagtag caaggctctc ttgacatttt tccttatccg cttgccaatc tccctcagaa
    18661 agacgatcta tttcctcttc ttggagtttc caaagagttt ccagttcttc aacttgctga
    18721 ctagtttgct gataagcgag ggacaagcct tgctcctgaa tacgtgcctg ctctccttga
    18781 gatttgatgg cttctaatct ttctgtcaat gcagccatct ggtcttgcaa ggtcttcaaa
    18841 gccgcttctt ctgaacccaa gcttgcttca tctgcagcaa tttctttttg taattgctcc
    18901 agttctggct tgatgaaaat actgttattt tggcgattgg caccacccgc ataggaacca
    18961 cccgtgcgta attctgtccc atccaatgtc accatacgaa cctgataacg aacttgtcga
    19021 gcagcttcac gcgcatgttc tacggtatca aagatagccg tcgtagctag caagttcttg
    19081 aaaatggctt ccagtctagt atcaaaagtc accaactcat ctgccatccc aaggaaacct
    19141 gggcttacag cgatagcatc ttggttctga ctagaaatcg tacgcgcctt aatagtggtc
    19201 aaaggaagaa aggttgcacg accgactctg tttcgtttga ggaaatcaat agctttggtt
    19261 gccgactctt catcttctac gatgatatgc tggctacttg cccctaaggc aatctctagg
    19321 gcagtttgat aataaacatc aaaggtcaga tgctcactga ctgcaccaat aatcccacct
    19381 aggcgatctt tttcttggag aacactctta acacctgcat aaaagttact atgatttctc
    19441 aggatatttt ccaaactttg agctctggcc tgcttgtttt tgagactatc cagacggtca
    19501 aagagttgac tttgttgagc ttgataggaa gttttctgct cctcttgctc cttggcaata
    19561 gcttgatagt cagccaataa tttctgaacc tgcaccttgg cagtttcaag ctcgtctttt
    19621 tgctgactag ccttctcttt agctgtagct aattgctctt tcagcttttc tagttgatct
    19681 gcttgttttt gagaaagctg acgactattt tccaactcat tctcaatacg ggtcaactgg
    19741 tttgagacat ccgcttcttc ttgtaaaaga gctacaaagc gttcacgtaa gagctcaatc
    19801 atctgatcag gatcgtctga gaaagccagc aattcagctt ctaaacgatt gagtttttga
    19861 ttattttgga ctagatttcc ctctaacaga gctaaagagc tttctttatc atacttttct
    19921 ttgctgagtg aatttctctt atcctccaaa gcagccaaac gagcttgtgc ctcctgttga
    19981 ttcagggcca cttgctcgga ctccagtttc gatagggcta attttctttc taaatcacta
    20041 atcagactag tcaagtccat caaactgcct tggtctttgg ccatttcagc ctgtaaatct
    20101 tggcgttgct ttttaagagt ttgattttct tcttctaatt tttcacgctt ttggtaataa
    20161 ctcatcaaga gttcttgaac ctgagccaac tcttcttctg tcgactctag ttctgcctta
    20221 ttttccttga tttgagcaac cagaacgtct aaataaatag ccttacgttg tccttccaag
    20281 tctaaaaact tacgggcatt ctcagcttgc ttctcaagag gcttgatttg attatccaac
    20341 tcgtagataa tgtcctctaa gcggtccaga ttatcctgag tttgctgcag tttactctcg
    20401 gtttcttttc tgcgagtctt gtattttaaa actccagcag cttcttcaaa aatagctcgt
    20461 cgttcctcag gcttggaatt aaaaatctcc tcaaccttcc cttgggaaat aatagagaag
    20521 gaatctcgtc ccaatccagt atccaagaag aggtcatgaa tatcacgcag acggactttc
    20581 ttgccgtcaa tcttgtattc gctatctcca ctacgataga tatggcgttc caccctgatt
    20641 tcttgacctg catccttgat aaatccgtca tgattatcca gagtcacaac tacagaagca
    20701 taattgagcg gtttgcgact ttctgttcca gcaaagatga catccggcat cttgccccca
    20761 cggagactct tgacactaga ctcccccaaa gcccaacgca gactttctgt aatattggac
    20821 tttccagatc cattgggtcc aacaactgcc gtcacacctt ggtcaaaaac gaccttggtc
    20881 ttatcagcaa aagacttgaa cccctgaatt tcgatttcct ttaaatacat gaatccagcc
    20941 ctttctcaac ggcatttttg gcagcttcct gctctgctaa tttcttagaa cgaccttggc
    21001 cttgaccgat gctcttacct tcaacaagaa cttctacatc aaagacctta tcgtgagcag
    21061 gccctgtttc agaaatcacc tgataacgaa tagccacatc accattgacc tgaagcaact
    21121 cttggagatg ggttttatag tctgtaatca tctcaaattc gcctgcttct accttaggaa
    21181 tcataacttg gtagataaat tccttgacct ttgccacatc cttatccaaa agaagggcac
    21241 caagaaaggc ttcaaaggca tcaccaagaa tggtgtcacg attgcgacca ccagattttt
    21301 cttccccttt acccaacttg ataaactggt caaactggca atcacgcgca aaaccagcta
    21361 aactctcctc acggacaatc atagcacgga gttttgatag gtcaccttca ggctttttag
    21421 gatatttttt atatagatat tctgaaatca ataactgtag aacagcgtct cctaaaaatt
    21481 ccaagcgttc attgtgtgaa atttttaaga ggcggtgctc attggcataa ctcgtatgag
    21541 taaaggcagt ttccagtaac tttttgtctg caaattcgat ttcaaaatga ttctttagta
    21601 cagtttgtaa ttctttcata ccaacttctt tctaactgat aatagtcctt tttattatat
    21661 caaaaaaagc cccctgagtc actctaaaac gggactggaa agcatttggg aattctttag
    21721 acagagattc tcagttttag cggcaaattt gggtcaggat aaagaaaaaa gccctattaa
    21781 aggcttttta ggatgtttac atccaccctg agggaatcga acccccatct caagaaccgg
    21841 aatcttacgt gatatccatt acactaaggg tggaaacttg ttttattata acagaaattt
    21901 gctctaataa caagtttttt ggtcaaagac cccgtcttag tgggaagcat ccccattcca
    21961 gatggagttt ttcacgatca cataatcaac gtgtttaagg tcagcaacct gacgtccacc
    22021 tgcataagaa atagcacttt gaaggtcttg ttccatctca gttaaagtgt cttgcagatg
    22081 acctttagca ggaagcaaga tacgtttgcc ttccacattt ttgtaagcac ctttttgata
    22141 ttgtgaggct gaaccataat attctttgaa ctgttcacca tcgacttcaa tcgttttccc
    22201 tggactttca atgtgtcctg caaagaggga accaatcatg atcatgctag caccgaagcg
    22261 gatagacttg gcaatatcac cgtgagtacg aattcctcca tcagcgataa tcggtttacg
    22321 cgcagccttg gcacaccagc gtagagcagc caactgccaa ccacctgtac caaaaccagt
    22381 cttaaccttg gtgatacaaa ccttaccagg accgattccg accttagtag catccgcacc
    22441 agcattttcc aattcacgca cagcttctgg tgttcccaca tttccagcaa tgacaaaggt
    22501 atctggcaat tctttcttga tgtgttgaat catagaaatc acgctatccg catgaccatg
    22561 agcaatatca atagtgatat actcaggagc atcagccttg agctggctaa caaaatcata
    22621 ctcatagtcc ttaacaccga cagagataga agcaatgagt ccttgatcgt gcatgcgttt
    22681 aataaaagga atgcgtcctg cctcatcaaa acggtgcata atgtagaagt aaccaccttt
    22741 agccagttgc tctgctacat tttcatccaa aatcgtctgc atattcgctg gcacaacagg
    22801 tagtttaaag gtgtgatttc ctaaagtgac acttgtatcc gcttctgcac ggcttttaat
    22861 gacacattta tttggaatca attgaatatc ttcgtaatca aaaattggaa attcatttaa
    22921 catatcgatg tctcgtttct tttgtaatga cctacctatg ctctcgcatc actacgcctt
    22981 ttccttaatt tattataaac taaagtacag tttttgtcaa attattttat gaattaaaat
    23041 atattgttcg ggttttgctt gtgttaaaaa taaaagaaag aggggaaatt attttctccc
    23101 cacttcttca tcaataatcg ctttaaaatt ttcttctgaa ttttccatca ttttacaaaa
    23161 tgcactatag aatgaggcat tctgagggat tcgaatagac cacttcttca attgagctcc
    23221 ataacctgct aggtttccca tctcattatc aataaccttg tccttgctcg gaaaaacaag
    23281 tccagccttc tcagctttta aaatataaga ataggaaatc agctggaata agtcctcacg
    23341 gttgattcct ttttcagtca attccagttt tttatatttt gcatctagaa caatctttcg
    23401 ttctctgtca taaaaatctg gatatacttt tcgtttccca acagaaaata ctgaaattcc
    23461 atccgtctta tccttatttc tgggatgtac aaaacctttt ggcaacaagg tgtaaacata
    23521 ctcttcccaa agccaggcaa catcaaagag aataccatag attttttgat cttgataccc
    23581 taaaccgtgc ttttcttggt ttaggatcat cagacaaagt tcttgtaagt ttctgtactc
    23641 gtgaaagtat gcatgacgta taggtttaga ttgatttctc cgagtaatct tagcacgatc
    23701 agctagttta taagagggcg ttacacgcac gatttcagat acgttttcac gactagttga
    23761 gagattatct agtacccctt gaccaatgct tttctgattc ttaatgtatt caatagtgtg
    23821 acggaccaac tgcatgaggg gattatcata ggtgaactct ctcgttgtgt aggcaatatt
    23881 tcccgtgaaa ggaagatttt tcttgagatg gtttcttaca tcaatcactc ccttaacatg
    23941 actgtcgtta tgagaaaatc tctggtattc cttataaaga ccttttcgaa tagcagcttg
    24001 tagatacttg gggaagagat acatcaaaag ttgataaagc ctctcttcac gagacaaagc
    24061 aacatctaaa ctagtgagat tgatatgaag aaccttgttt aagagataat gcaaaaaatg
    24121 gtcattactc tcatcagaaa atcgtgagga aatcgttaat ctttcctgac catatccaag
    24181 aaaaccaatc acgttccctg tcttgatttt ctgattgact gtttcaaaaa tcttttggtc
    24241 cttatccaaa tcaggagtat gagtcaaatc atttggaaaa atgaaaatac gttcatcttg
    24301 ggatagactt tccaaggttc tgtctaaaag aagattgctt agtttaggat attcttcaac
    24361 aaatttttct ttaataatct tgtgttgatt atcagtaatc cgcatcatcg ttttcatcgc
    24421 cttcattgtc atcagctact gcctgatctt tttgctcatt atttgtcagt tcaaatgctt
    24481 ttttcaaagt ttccaaagtt tcaacctcat cataagaacc tcgcaagtag tcttctagga
    24541 gaggcttaat ataatcagac cagagtaatt catagtcaaa atctacatcc ttcaacttaa
    24601 gaaaataact tggtccaata tgataatgac tgtttaattc ctgaacattt tcgatagcag
    24661 cgttcaagtt tcttagacga atttttgctt cttctgcatg gatattcagc tctttatcca
    24721 acatgccaac ttgaccctcg gcagtaactt caacaaaacg aaaacgacga cgcatagcaa
    24781 aatcaaaggt atccactgaa cgatcaatat cattcatagt tccgatgatg taaacatttt
    24841 cggggatata gaacttttca tcagtttcgt gtagatttgc atattgggta gaaacacttc
    24901 ctttttcacc acgatagtca gggtcgatag agaaaaagag ttcgccaaaa atcttagaaa
    24961 tctccccacg attgatttca tcgatgatga agacgaattt cttatcagta tcaatttctg
    25021 ttggggaaac atagtctttc aaaccaaatc tctttctcaa tgtttctagg acagtttttc
    25081 caccactttt gtagtattct tgcttattat aatttttatc tttatacaac tcgtaaacat
    25141 atttgctagg tagtgaccat cctggaacac cactatcata atttactgac aaattttgtc
    25201 tactattaac ag
//
LOCUS       DBERXF010000033        25107 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.33, whole genome shotgun sequence.
ACCESSION   DBERXF010000033 DBERXF010000000
VERSION     DBERXF010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.33"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..341)
                     /locus_tag="ACL8JK_001491"
                     /pseudo
     CDS             complement(1..341)
                     /locus_tag="ACL8JK_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            568..888
                     /locus_tag="ACL8JK_001492"
                     /pseudo
     CDS             568..888
                     /locus_tag="ACL8JK_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            1009..1953
                     /gene="manA"
                     /locus_tag="ACL8JK_001493"
     CDS             1009..1953
                     /gene="manA"
                     /locus_tag="ACL8JK_001493"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGS1786356.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(1944..3339)
                     /locus_tag="ACL8JK_001494"
                     /pseudo
     CDS             complement(1944..3339)
                     /locus_tag="ACL8JK_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3545..4290
                     /locus_tag="ACL8JK_001495"
                     /pseudo
     CDS             3545..4290
                     /locus_tag="ACL8JK_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(4319..4774)
                     /locus_tag="ACL8JK_001496"
     CDS             complement(4319..4774)
                     /locus_tag="ACL8JK_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGS1786357.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4794..5969)
                     /locus_tag="ACL8JK_001497"
     CDS             complement(4794..5969)
                     /locus_tag="ACL8JK_001497"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS1786358.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELDGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(6028..6873)
                     /locus_tag="ACL8JK_001498"
     CDS             complement(6028..6873)
                     /locus_tag="ACL8JK_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS1786359.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6998..7555
                     /locus_tag="ACL8JK_001499"
     CDS             6998..7555
                     /locus_tag="ACL8JK_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGS1786360.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7574..8041
                     /locus_tag="ACL8JK_001500"
     CDS             7574..8041
                     /locus_tag="ACL8JK_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HGS1786361.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            8130..8759
                     /gene="upp"
                     /locus_tag="ACL8JK_001501"
     CDS             8130..8759
                     /gene="upp"
                     /locus_tag="ACL8JK_001501"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGS1786362.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8933..9523
                     /gene="clpP"
                     /locus_tag="ACL8JK_001502"
     CDS             8933..9523
                     /gene="clpP"
                     /locus_tag="ACL8JK_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HGS1786363.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9602..9850
                     /locus_tag="ACL8JK_001503"
     CDS             9602..9850
                     /locus_tag="ACL8JK_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGS1786364.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9951..11111
                     /locus_tag="ACL8JK_001504"
     CDS             9951..11111
                     /locus_tag="ACL8JK_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1786365.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            11379..12248
                     /locus_tag="ACL8JK_001505"
     CDS             11379..12248
                     /locus_tag="ACL8JK_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGS1786366.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            12252..13208
                     /locus_tag="ACL8JK_001506"
     CDS             12252..13208
                     /locus_tag="ACL8JK_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGS1786367.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSTSPTYGAFFGAMLVGALLSG
                     VVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            13208..13972
                     /locus_tag="ACL8JK_001507"
     CDS             13208..13972
                     /locus_tag="ACL8JK_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1786368.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13972..14682
                     /locus_tag="ACL8JK_001508"
     CDS             13972..14682
                     /locus_tag="ACL8JK_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1786369.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKIPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14990..15646
                     /locus_tag="ACL8JK_001509"
     CDS             14990..15646
                     /locus_tag="ACL8JK_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGS1786370.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIISL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15754..16849
                     /gene="prfB"
                     /locus_tag="ACL8JK_001510"
     CDS             join(15754..15825,15827..16849)
                     /gene="prfB"
                     /locus_tag="ACL8JK_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGS1786371.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTELD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16867..17559
                     /gene="ftsE"
                     /locus_tag="ACL8JK_001511"
     CDS             16867..17559
                     /gene="ftsE"
                     /locus_tag="ACL8JK_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGS1786372.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17552..18478
                     /gene="ftsX"
                     /locus_tag="ACL8JK_001512"
     CDS             17552..18478
                     /gene="ftsX"
                     /locus_tag="ACL8JK_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGS1786373.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTEKLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18764..20944
                     /locus_tag="ACL8JK_001513"
     CDS             18764..20944
                     /locus_tag="ACL8JK_001513"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGS1786374.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPIFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVTAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20996..21811
                     /locus_tag="ACL8JK_001514"
     CDS             20996..21811
                     /locus_tag="ACL8JK_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGS1786375.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            21951..23294
                     /locus_tag="ACL8JK_001515"
     CDS             21951..23294
                     /locus_tag="ACL8JK_001515"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS1786376.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23509..24699
                     /gene="metK"
                     /locus_tag="ACL8JK_001516"
     CDS             23509..24699
                     /gene="metK"
                     /locus_tag="ACL8JK_001516"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGS1786377.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(24827..>25107)
                     /locus_tag="ACL8JK_001517"
     CDS             complement(24827..>25107)
                     /locus_tag="ACL8JK_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1786378.1"
                     /translation="DPEKFFGLIEDNLKQVHPIFQTVFKTFLKNKEKIVNALQLPYSN
                     AKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSQA"
BASE COUNT         7633 a         4672 c         5484 g         7318 t
ORIGIN      
        1 tctactggtt ttaaagcgct ttcttttctt cttgaattga gattttattt ttagacgcga
       61 caatggtttg agcgtctgct ttcttaggat gttctggacg tggcgtaata tttcgccaac
      121 catggcgctt caacagttga tagaaggcat cacgtgtgta ggaatgacct aactccttct
      181 atagtgtatt gaatctataa cagtacacct tggctgctaa aatatttcta taaattaatt
      241 tgacttttct gatagagttg ttcacatctt atttcaaact actataaaag ttctataatc
      301 tctttataag atttgcccat cagacgaaat ataatggatt gaaactagaa tagtacacct
      361 ctacttctaa aacattgtta gaaatcgatt tgactgtcct gattgatttg tcctgttctt
      421 gtttcatttt actatagaac gatttgaagg cgtttatgat atttagctgt acgagagtct
      481 tttaaaagtg ttttgatggt ttggatttct tctttagttg atttcatatc actattatat
      541 aatgcttttt gattttagtt tagtattatc gtagaaaatg gactcggtgc tatggataca
      601 ccggatgaga atggttatgt agcagataac tatcggatta cttacttaga ggcccacatc
      661 aaggccatgc gagatgccat ttaccaagac ggggttgact tgcttggtta tacgacttgg
      721 ggctgtatcg atctggtttc agctggcaca ggggaaatga ataagcgcta tggctttatc
      781 tatgtagatc gagataatgt aggaaacgga gctctcaaac gtagcaagaa gaagtccttc
      841 tattggtaca aggatgtcat tgatagcaat ggtgcaagca tcgggtagag cacatttgtt
      901 tactattttt ataaaatctt ctccctgctt tataagatgt aaaaaagagt tcaattcgaa
      961 ctcttttttt gctataatga ggggagaaaa atcagacagg agatcgacat gtcagaacca
     1021 ttatttttac aatcagttat gcaagaaaaa atctggggtg gagccaagct acgtgatgag
     1081 tttggctacg acatcccaag tgaaaaaatc ggagaatatt gggccatctc agcccatcca
     1141 aatggagtct ctaaagttgc caatggtcgt tacgagggaa cagatcttgc tactttgtat
     1201 gcggaacacc gtgaattatt tggcaatcgt ccagaacctg tatttccact tttgaccaag
     1261 atcctcgatg ccaacgactg gctcagtgtc caagttcacc cagacgatgc ttatggactc
     1321 gagcatgaag gcgaactcgg aaaaacagaa tgctggtaca ttatcgcagc ggatgaaggt
     1381 tcagagatta tctacggtca caatgccaag tcaaaagaag aactccgcca gcaaatcgag
     1441 gataagaact gggatgcgct gttgacaaaa gtgccagtta aagcaggaga tttcttctat
     1501 gtaccaagcg gtaccatgca cgctatcggg gcgggtatct tgattcttga aacccagcag
     1561 tctagcgata ccacttaccg tgtctatgac tttgaccgta aggatgacaa gggcaattta
     1621 cgtgaacttc accttgaaaa atctatcgat gtcttgaaca ttggtgaacc cgcaaatagc
     1681 cgtccagtga caatcaaagc agatgatcta cgttccactc tccttgtatc caatgatttc
     1741 ttcgcagttt acaaatggga aattactgga aaagttaact ttgaaaagac agctgactac
     1801 agcttgttga gtgtcttggc tggtcaaggt caactaactg ttgacgggaa aaactatcca
     1861 atccaaaaag ggagacactt tatcctacca agtgatgttg aagcttggac tctggaaggg
     1921 caagatttag aattaattgt tagtcatcca taaaaaagaa agggcctgag ttcattactc
     1981 aagtcctttt gattacataa attgggcgat gaagaccacg atgatgattg gaatgacgga
     2041 acgaagaaac gaagaaggaa gagccagact tggaacagtc cttgtttcca tgctctttca
     2101 tcgagatgga gttcctccat tgcaagagcc tttttaaaga tatagcctgt aaaaagtgaa
     2161 aggtagagag ctccaaatgg catgaggaga ttggaaacca agaagtccat agcgtcaaag
     2221 aaggtcttac caaaaatgtg aacatccgcc atgacaccgt aagatagggc tgaaggaatg
     2281 ccaaagacaa aggtcaaaat tcctaaaata acactccatt tggcacgttt gctgttatcc
     2341 tggttggtga tattgcccac attgatctcc agcatcacga cagaagaagt gacagtcgca
     2401 aagaggaaga ggacgtagaa aatggttcca aaaggcatct tgtcaaagag ttgaggcaag
     2461 acgataaaga gcaagctcgg tcccccttca gactggatat tgaaggggga tcgagcttgg
     2521 aaaatggcta gacctgccat gatggatatc gagatattca tggctacgat ggagattcct
     2581 gactggacta gattggtttt cttgtccaag taaggagcat aggtcaacat gactgtaacc
     2641 cctagtgaga gggcaaagaa agattgtccc agagcataga ggagaccagc gctagtcagt
     2701 tttgaaaagt ctggtttgag gaagtaaaga acccttccat ggcatttggc aaactgagag
     2761 agcgaccgat gataacaaca aagatgataa agagcagggg catcatgact ttcgaagctc
     2821 tttcaatccc tttttgaaca ccacgtgata caataaagat atttaataag ataaaggctg
     2881 cttgagctac tagggcaatg gctggatttg aaatgattga agtaaataac tgagcataat
     2941 cacccgttcc accaagttgg aacaatttcc caaactcaat acctagatag actagaatcc
     3001 atcctccgat aacactgtaa aaagataaga ggataaagag ggcaaaggcg ccaatccaac
     3061 cgataaagtt gtacttgtta ttcttgccca gttttccaaa ggttttgata gcggaaacgc
     3121 cagccactac ggccaagggc aaactcagcc agcaggagag ggaaaccgat taaaatagtg
     3181 gaaatgagaa agattagtaa aaagcctcca ccgccattag cagcagtcat gtagggaaac
     3241 ttccaaacgg aaccaagccc gatgaccgag cccgatgacc gagccagcag atgctagaat
     3301 aaagccaagt ttcgaccccc attgtgattt ttctgacata gttaaactct gatctccttt
     3361 ttcaaaataa gaaaaagcta cttgagttgt caaatagcct tctgtttgat tgatagactt
     3421 gactatccta ttatgttttc taaggtctgt caagaaaacc attttcaagt tttcacacct
     3481 ttctcaaaaa cgcttgactc tgacctaagg ggaggggtta tactatcatt gtaaggagga
     3541 aatcatgtac catataaaag aagctgcgca gctttcaggt gtctctgtca agaccctgcc
     3601 ctgcatcact atgacaagat aggactcttg gtccccttaa agtcggaaaa cggctatcga
     3661 acctatagtc aagaggattt ggaacgcctt caggtcattc tttactacaa atatctaggc
     3721 ttttctttag agaaaatagc agaactgtta aaggaagaaa ggacagattt attgccccat
     3781 ttgactaggc agttggacta tctaactcgc gaaaggcaac atctggatac cttgatttcc
     3841 accttgcaaa aaactattca agaacaaaaa ggagaaagaa aaatgaccat tgaggaaaaa
     3901 ttcacgggat ttagctatca agacaatcaa aaataccacc aagaagcggt agagaaatat
     3961 ggtcaagaag tcatgggaca agcgctcgaa cgccaaaaag gtcacgaaga cgaggctacg
     4021 gccgccttta accaagtctt tcaaactttg gcacaaaatc ttcaagttgg tttacctgca
     4081 acagcaaccg aaaaccagga gcaagcagcc aagctcttgc aagccattcg cacttatgga
     4141 tttgactgct ctattgaggt attcggtcat atcggtaaag gttacgtcta caacccagag
     4201 tttaaggaaa acattgacaa gtttggttct gaaacagccc agtacacgtc agatgccatt
     4261 gcggcttacg ttcagacaaa tgcagaataa ataggctagg aatttcctag cctatttttt
     4321 acttcaaatc ataaagccag tcgtcaccgt ttttgtagta aaagaattca ctgagatctt
     4381 cttctagaaa cacacgaagc atatcagaca tatcatcggt tgcaagtttt agatgagaaa
     4441 gattttcaaa gtcctcccac caaactttcc cttcgtctga agactggagt tcaccagtaa
     4501 agtgttctgt cttgtaaaaa aggacgacat aacgataatc cttgtcgtca taccagtttt
     4561 tgataccaca gagttggggt ttggaaatga tcagaccagt ttcttctttc acttcacgaa
     4621 tgacagcatc gacaaaggat tcgccacgtt caacatgacc accaggaaaa gtaatgccag
     4681 accagtcggg actaactcgg tcttggacca ggaccttatc tccgttttta atcatacaca
     4741 tgttaacaaa ttcgactgcc tctcttctgt tcattcttca caacctttaa tctttaatca
     4801 taatgcagac ttcccgccac ccagccggta cagagggcag aagtgatgtt aaagccaccc
     4861 gtgtgggcat tgatatccat aacttcgcct gcaaagtgga ggccaggtac cagcttactt
     4921 tcaagggttt taggattgat ttccttgaga ctgactccac ccttggtaac aaaggacttt
     4981 gcaagggaca tttttccagt tacaggaatt ttaagttctt taatggactg gacaagttgt
     5041 tctcgttcct tttcagtcag ttgtttgact ttttcaggat atccttgtac aaaaaattcg
     5101 gccaagcgtt ctggtaacaa ggtttttaaa gcgtttttca aggatttttc ccgattttct
     5161 tctagaaatg taaccaagtc cttctcagaa agttgaggca aaacatcgag tgagagaacc
     5221 tccccacctt tgacaaagct agacatgcgt agggcagcag gacctgacaa accaaagtgg
     5281 gtaaagagta aatcatgagt gatgacatgc ttaccataac ttagggtcac atcgtccaga
     5341 gaaatccctt gtaaggcttt atgtggaaaa tctgttaata aaggactttc agcagcctca
     5401 agatcggtga tggtatgctt aaaatggcga gcaatctcgt gaccaaaacc agtcgaacca
     5461 gtcgaaggat aagacttacc acctgttgtg acaatgagtt tctcacaagt gaaggtttga
     5521 tccgctgact taaggacaaa ctggtcatct acttttttaa cagaaacgat ttctatttga
     5581 gtagcaactt gaccatctag ttcggtgatt ttcttttcca aagcttcgat aatagtccga
     5641 gacttgtcac tggctggaaa gacgcgtccg tggtcttcga ccttaagttt aacaccattt
     5701 tctgtaaaaa agttgatgat gtcatgatta tcgaactggg agaaaacact gtaaagaaag
     5761 cgtccgtttc caggaattcc agctagcagg ttgtctaagc taccattgtt ggtcacattg
     5821 caacgtcccc caccagtccc agctaatttt tttccaagtt tccgattttt ttcgatgagg
     5881 agggttttct gtccataaaa gctactggaa atcgtagcca tcataccagc aggtccccca
     5941 ccgatgacaa tagtatcaaa atgtttcata gctctattgt accacaaaaa aacaagagat
     6001 gatggtcacc tcttgtcaag aatgcaatta atcaatttca tagcccatca gcaaaccgcc
     6061 ctcttctgca tagaaactgc agagaccaga ggttggtaga attttaatat ccgcttgtgg
     6121 gaaggtttca cggattcgct ctgagagctg ttgacaacat ttttcgttat tgcgttgggc
     6181 catgacaata cggccaccag catatccagc ttttactaac tcatcatagg cagcttgaac
     6241 tgatttcttt gatccccttg ctttttgtag caattcgaga gtcccagttt cactagcttt
     6301 tccgaccata cgaatgttga gaaggccaac gaccgtaccg ataagcttgc tcaaacggcc
     6361 gttcttcacc aagttatcga ctttggctag gacaaagagc aacttagttt tttcttgata
     6421 ggcggtgata gcttcaacca cttcttcaaa agacaagccc tggtcaatca agtcattcaa
     6481 tttttctacg agtaggtcaa cttcaccacc agcagataaa ctatcaatca catgaatctt
     6541 agtgtcagga tggtcttcca gataaatatt ctttgctagt tgagcactat tgtgactgcc
     6601 agaaagggta cctgtgatgg ttactaggaa aatgtttttg gcaccttcaa atgctcgcaa
     6661 atagtcatct gggcttggac aagctgattt tgaagcttct gcagttgcat acatggtttc
     6721 catcatttgg tcaatatcga gactggcgtc atcaacaaag acctgatcag ctacttgaat
     6781 ggttaagggg acacttacaa aggttgtgtt aatagctggt gttggcagtt gacgataatc
     6841 acaaccagag tcagcaataa tcttccaagt catagaaatt ctccatcttt gtcagttata
     6901 cattgacaaa ggttctgtct ttttttacaa ttatatcatg aaaactcttg aaacaaaagc
     6961 atcatccgtc tgttgtgaca agtagaaaga aaatgttatg tctgaacgta gaatctctga
     7021 aaagtctctt gaaaatctca gaaaatcaaa ccaagaatcc aatttattaa ccagagaagc
     7081 cattgaaaca gccctcttgc aactcttgga aaaaaaggag ctgaccaaga ttagtatttc
     7141 tgaattggtc aaacgtgcag gtgtttcgcg tgcggccttt tatcgcaatt atgactccaa
     7201 agaggaaatt ttagagagcg tctttaaacg aactgtccac aatattatgg aacagctgca
     7261 tcattacgat ttaaagacag acctttattt ggtttgggtt caccttttcc gggaggccag
     7321 aaaggaagct agagtaattc aattggcctt ggattaccat ctggaaaaaa tctttgtcca
     7381 agccatgcag gaatttctag aaaaatacca tgggaaatca aaaggtgtca gctcttatct
     7441 tcattccttc tggagctcag ccatcgtctc tgtccttcta aaatggatca aggatggcat
     7501 gaaggtacca gctgaaaaga ttgcagattt aggtttacca ttttttaaaa aatagagaaa
     7561 aaggagaaaa gagatgactg aaaaaagact ggcctgggat gagtattttg cagcccaagc
     7621 tctactaatt gcgaatcgtt ccacttgtaa acgtgctaaa gtgggcgcga ttctggtaaa
     7681 agataataag gttatttcca ctggttacaa tggttcggtg tcagggactg agcattgtat
     7741 tgatcacgaa tgtttggtca ttgaaggcca ctgtgttcgc acccttcacg ctgaggtcaa
     7801 tgctatcctt caaggtgctg agcgtggtgt tcccaaaggc tttacagcct atgtaaccca
     7861 ttttccttgt ctcaactgta caaaacaatt gcttcaggtc ggctgcaagc gcgtggttta
     7921 tatcaaccag taccgaatgg acgactacgc ccaatacctt tatcaagaaa aagggacaga
     7981 attgacccat ttaccacttg agacagtaca gacagctctt aaagaggctg atctaatgta
     8041 aaaattatca aaaataaatg gtttagaaag atttttaaac cgttttttgg tataataaga
     8101 agaataaatt gaaagaagga attccaaaaa tgggaaaaat tgaagttatt aatcacccac
     8161 tgattcaaca caaattgtca atcttgcgtc gtacagatac ttctacaaaa gcttttcgtg
     8221 agctagtaga tgagattgca atgttgatgg ggtatgaagt acttcgtgat cttccactag
     8281 aagatgtgga aatcgaaaca ccaattacaa aaacagttca aaaacaattg gcaggtaaga
     8341 aattggccat cgtcccaatc ttgcgtgcag gtatcgggat ggttgatggt ctcttgagct
     8401 tggttccagc tgctaaagtt ggccacatcg gtatgtaccg tgatgaagaa acacttcaac
     8461 cagttgaata cttggtgaaa ttgcctgagg acattgacca acgtcaaatt tttgtagtag
     8521 acccaatgtt ggcaacaggt ggctcagcaa tcttggctgt tgattctctt aaaaaacgtg
     8581 gcgcatcaaa tatcaaattt gtctgccttg tatctgctcc agagggtgta aaagcccttc
     8641 aagaagctca tccagatgta gaaatcttta cagcagcctt ggatgaacgt ttgaacgaac
     8701 acggttatat agttccaggt cttggagatg ctggagaccg cttgttcggt acaaaataag
     8761 atcgaaaaga agaatgactt ggaaaagtat ttctagtcac gaaaggaggt tgggtttttg
     8821 tttctgtcta atgaaagcag agcaaaaatt tgaccttttt tgaccaagat attataatag
     8881 tcttatcttc agtcatttga ccaacaaaat taaaactcaa aaggagaaat gaatgattcc
     8941 tgtagttatt gaacaaacaa gccgtggaga acgttcttac gatatttact cacgtcttct
     9001 caaagaccgc atcattatgc tgacaggtcc ggttgaagac aatatggcta actctgttat
     9061 tgcccaattg cttttcttgg atgcccaaga tagtacgaaa gatatttacc tttatgtcaa
     9121 tacaccaggt ggttctgttt cagctggttt ggcaatcgta gataccatga actttatcaa
     9181 ggcagatgtc caaaccattg ttatgggaat ggctgcatct atggggactg tcatcgcatc
     9241 aagtggagca aaaggcaaac gtttcatgct tccaaatgct gaatacatga ttcaccaacc
     9301 aatgggcggt acaggtggtg gtacccaaca aactgatatg gctatcgctg cagaacactt
     9361 gctcaaaact cgtaatacct tggaaaaaat cttggctgaa aattcaggtc agtcaatgga
     9421 aaaagtccat gcagatgcag aacgtgataa ctggatgagc gcccaggaaa cacttgaata
     9481 tggctttatt gatgaaatta tggccaacaa ttcattgaac taatgatgat agaaggcaaa
     9541 ctcgactggg tttgcttttt ttggtataat agggagagat ttcttagaaa gaggatttat
     9601 catgtttgaa aaagtcaatc gctctggctt gattatctat ctttactata atcgtgatgc
     9661 caaaaaactg caggattatg gagatattac ctatcattcc aagaaacatc gttacttaca
     9721 actctatgtt ccaactcaag aagtggagca attggtcgga cgcttgagca aggaaaaatt
     9781 tattaaaaaa gttagggttt gtcatatcca agagttggaa acaccctttg tgggcaatct
     9841 ttatcgatag gaaaacgtta tcatcgaaaa agttcaagga aaacattgac aattttctga
     9901 taattcggta tattcttaac agactattta agaaataagg agacaaaaag atgaagaaaa
     9961 aatttgccct atcgtttgtg gcgcttgcaa gtgtagcact tcttgcagcc tgtggagaag
    10021 tgaagtctgg agcagtcaac actgctggta actcagtaga ggaaaagaca attaaaatcg
    10081 ggtttaactt tgaagaatca ggttctttag ctgcatacgg aacagctgaa caaaaaggtg
    10141 cccaattggc tgttgatgaa atcaatgccg caggtggtat cgatggaaaa caaatcgaag
    10201 tagtcgataa agataataag tctgaaacag ctgaggctgc ttcagttaca actaaccttg
    10261 taacccaatc taaagtatca gcagtcgtag gacctgcgac atctggtgcg actgcagctg
    10321 cggtagcgaa cgctacaaaa gcaggtgttc cattgatctc accaagtgcg actcaagatg
    10381 gattgactaa aggtcaagat tacctcttta ttggaacttt ccaagatagc ttccaaggaa
    10441 aaattatctc aaactatgtt tctgaaaaat taaatgctaa gaaagttgtt ctttacactg
    10501 acaatgccag tgactatgct aaagggattg ccaaatcttt ccgcgagtca tacaagggtg
    10561 aaatcgttgc agatgaaact ttcgtagcag gtgacacaga ctttcaagca gcccttacaa
    10621 aaatgaaagg gaaagacttt gatgctatcg ttgttcctgg ttactataat gaggctggta
    10681 agattgtaaa ccaagcgcgt ggcatgggaa ttgacaaacc aatcgttggt ggtgatggat
    10741 tcaacggtga ggagtttgta caacaagcaa ctgctgaaaa agcatcaaac atctacttta
    10801 tctcaggctt ctcaactact gtagaagttt cagctaaagc taaagccttc cttgacgctt
    10861 accgtgctaa gtacaatgaa gagccttcaa catttgcagc cttggcttat gattcagttc
    10921 accttgtagc aaacgcagca aaaggtgcta aaaattcagg tgaaatcaag gataaccttg
    10981 ctaaaacaaa agattttgaa ggtgtaactg gtcaaacaag cttcgatgca gaccacaaca
    11041 cagtcaaaac tgcttacatg atgaccatga acaatggtaa agttgaagca gcagaagttg
    11101 taaaaccata atagaaaaat gttgaaatag ggaatgagcc tttgactcac tccctgtttc
    11161 gatatttaat actcttcgaa aatctcttca aactgcgtca acgtcgcctt ggattatata
    11221 tgtgactgac ttcgtcagtc ttatctacaa cctcaaagca gtgctttgag caacctgtgg
    11281 ctagtttcct agtttgctct ttgattttca ttgagtataa gaacctatca aaaagtgagg
    11341 gaaacccctc ggaattataa atagaaagag tgaatcttat gctacaacaa ctcgtaaatg
    11401 gtttgattct aggtagtgtt tacgcgctgt tagccctagg atataccatg gtttacggaa
    11461 ttatcaagct catcaacttc gcccatggtg atatttatat gatgggagcc tttatcggtt
    11521 atttcttgat caattctttc caaatgaatt tctttgtagc gcttattgta gctatgctag
    11581 cgacagctat tcttggtgtc gtgattgagt ttcttgctta ccgacctttg cgccactcta
    11641 ctcgtattgc tgttttgatt acggctattg gggtttcttt cctattggag tatggaatgg
    11701 tctatctggt tggtgccaat acccgtgcct tccctcaagc gattcaaaca gttcgatatg
    11761 atttgggacc aattagctta acaaatgtgc agttaatgat tttggccatt tccttgattt
    11821 tgatgatttt gttacaagtc attgtccaaa agactaagat ggggaaagcc atgcgtgcag
    11881 tatcagtaga tagcgacgcg gcgcaattga tggggatcaa tgtaaaccgt acgattagct
    11941 ttaccttcgc tttgggttct gctcttgcgg gtgcggctgg tgttctgatt gctctttatt
    12001 ataactctct tgagcctttg atgggggtta ctccaggtct taaatctttc gttgccgcag
    12061 tacttggtgg tatcggaatt attcctggtg cggctcttgg tggctttgtg attggtctat
    12121 tggaaacctt tgcgactgcc tttgggatgt cagatttccg tgatgccatt gtttatggaa
    12181 tcttgttgtt gatcttgatt gtccgcccag ctggtatcct tggtaagaat gtgaaagaga
    12241 aggtgtaaac gatgaaggaa aatttaaaag ttaatattct atggttactc cttttgttag
    12301 ctggctatag cttgattagt gtactggttt cagtcggagt acttaatcta ttctatgtac
    12361 agattttaca acaaattgga attaatatta ttttggctgt tggtctcaac ttaatcgttg
    12421 gtttttcagg acaattttca cttggtcatg ctggtttcat ggcgattggt gcctatgcag
    12481 cagctattat tggttctaca tcaccaacct acggtgcctt ctttggagct atgcttgtag
    12541 gggctttgct ttcaggagta gttgccttac ttgtcggcat tccaaccttg cgcttgaagg
    12601 gggactatct tgcggtagca actctgggtg tttctgaaat tatccgtatc tttatcatca
    12661 atggtggaag tcttacaaat ggtgcggcag gtatcttagg gattcctaac tttacaactt
    12721 ggcaaatggt ttacttcttt gtcgtgatta caaccattgc aaccttgaac ttcttgcgta
    12781 gcccaattgg ccgttcaacc ctctctgttc gtgaagatga aatcgctgct gagtcagttg
    12841 gggttaatac gactaaaatt aaaatcatcg cttttgtctt tggtgccatt actgcaagta
    12901 ttgctgggtc acttcaggca ggatttatcg ggtctgttgt accgaaagat tacaccttca
    12961 tcaactcaat caacgttttg attattgttg tatttggtgg actcggttcc attacaggtg
    13021 cgattgtttc ggctattgtt ctgggaattt tgaatatgct tctccaagat gttgctagtg
    13081 tgcgtatgat tatttacgct ttggccttgg tattggtaat gattttcaga ccaggtggac
    13141 tccttggaac gtgggaactg agcctatcac gtttctttaa aaaatctaag aaggaggaac
    13201 aaaactaatg gcattacttg aagtaaaaca gttaaccaaa cattttggtg gtctaacagc
    13261 tgttggagat gtgactcttg aattgaacga aggggaactg gttggattaa tcggtccaaa
    13321 cggagctggg aaaaccaccc ttttcaacct tttgaccggt gtttatgaac caagcgaggg
    13381 aacagtaacc ctagatggtc accttttgaa tgggaaatca ccttataaga ttgcctcttt
    13441 gggacttgga cgtactttcc aaaatatccg tctttttaaa gatttaacag ttttagacaa
    13501 tgttttgatt gcttttggaa accatcacaa acagcatgtt tttactagtt tcttacgctt
    13561 accagctttt tacaagagtg aaaaagaatt aaaggctaaa gctttggaat tgttgaaaat
    13621 ctttgattta gatggtgatg cagagactct tgctaaaaat ctttcctacg gacaacaacg
    13681 tcgtttggaa attgttcgtg cccttgctac ggaacctaaa attctcttct tagatgaacc
    13741 agcagcaggt atgaacccac aggaaacagc cgaattgact gagttaattc gtcgtatcaa
    13801 agatgaattt aagattacaa tcatgttgat tgaacacgat atgaatctgg tcatggaagt
    13861 aacagaacgt atctacgtac ttgaatatgg ccgtttaatt gctcaaggaa ctccagacga
    13921 aattaagacc aataaacgcg ttatcgaagc ttatctagga ggtgaagcct aatgtctatg
    13981 ttaaaagttg aaaatctttc tgtgcattac ggtatgatcc aagcagtccg tgatgtaagc
    14041 tttgaagtta atgaaggaga agttgtttcc cttatcggtg ccaacggtgc aggtaagaca
    14101 actattcttc gcaccttgtc aggtttggtt cgaccaagtt caggaaagat tgaattttta
    14161 ggtcaagaaa tccaaaaaat accagctcag aaaatcgtgg caggtggtct ttcacaagtt
    14221 ccagaaggac gccacgtctt tcctggcttg actgttatgg aaaatcttga aatgggagct
    14281 ttcttaaaga aaaatcgtga agaaaatcaa gctaacttga agaaggtttt ctcacgcttt
    14341 cctcgtcttg aagaacggaa gaaccaagat gcagctactc tttcaggagg ggaacaacaa
    14401 atgcttgcca tgggacgcgc tcttatgtca acaccaaaac ttcttctttt agatgaacca
    14461 tcaatgggac ttgccccaat cttcatccaa gagatttttg atatcattca agatattcag
    14521 aagcaaggaa caaccgtcct cttgattgaa caaaatgcca ataaagcact tgcaatctct
    14581 gaccgaggat atgtactgga aacagggaaa atcgtcctat caggaacagg aaaagaactc
    14641 gcttcatcag aagaagtcag aaaagcatat ctaggtggct aaaacaatcc agtggattgt
    14701 tttagtcggc agatggagat tacgaagtaa tcatcaatat agtccggggg acctttttag
    14761 tcggtagatt gagattgcaa acaaatctgc atctacattg aaagcttaat ttctaataat
    14821 tgaaaaaatc gaatgaaaag tttcttacct tcattcacag agctcgattt tagagctctt
    14881 tttgctagct tattcatact tttctaaatt ttgaaaaaga aatgtaagcg tttgatagat
    14941 ttgcaaaaag attgtataat agggataaga atagaaaagg agaagtctca tggcagttaa
    15001 agattttatg acccgcaagg tagtttatat tagtccagat acaacagtat ctcatgcagc
    15061 agatttgatg agagagcaag aattgcaccg cttgcctgtt atcgaaaatg atcaattagt
    15121 tggtttggtg actgagggaa ccattgcaca agcaagtcca tctaaagcaa caagtctttc
    15181 tatctatgag atgaattatc ttctgaataa gacaaaagta aaagatgtca tgattcgcga
    15241 tgttgtcact gtctcaggct atgctagtct agaagatgca acttatctga tgttgaaaaa
    15301 taagattggt attctccctg tcgtagataa ccatcaagta tacggagtta ttactgaccg
    15361 tgacgttttc caagcctttc ttgaaattgc aggttatggc gaagaaggga ttcgtgtacg
    15421 ctttgttaca gaagatgaag ttggtgttct tggaaaaatt atttctttga ttgtagaaga
    15481 aaatttgaat atatcccata cagtcaatat tccgcgtaag gatggtaagg tcattatcga
    15541 agtgcaaatc gatggatcaa ttgatttacc agccttgaaa gaaaaatttg aagcaaatgg
    15601 tattcaagtg gaagaaatcg ctcgcacttc agcaaaagtc ttgtaagaag ggaagcccaa
    15661 aggcttcttt tttcatgaaa aggggattag agcaaaagat ggaaagaaat gataaaatat
    15721 gctataatga aataatgtaa aaaaggagta tttatggaca tttcagtaat tcgtcagaaa
    15781 attgacgcaa atcgtgaaaa attagcttct ttcagggggt ctctttgacc tcgaagggct
    15841 agaggaagag attgccatct tggaaaacaa gatgacagaa cttgattttt ggaacgataa
    15901 tattgcggcc caaaaaacgt cgcaagaatt gaatgaatta aaaaacactt acaatacctt
    15961 ccataagatg gaagagttgc aggatgaagt cgaaatttta ttggattttt tggctgaaga
    16021 cgagtcagtg catgatgaac tggtagcgca gttagccgaa cttgataaga taatgaccag
    16081 ctacgagatg actctactct tgtcagaacc ttatgaccac aacaatgcca tcttggaaat
    16141 ccatccaggt tctggtggta ctgaggcgca ggactggggt gatatgttgc ttcgtatgta
    16201 tactcgttat ggtaatgcta aaggctttaa agtggaagtg ttggattacc aagcaggtga
    16261 tgaggctggt attaagtcgg taactttatc atttgaaggg cctaatgcct atggtctcct
    16321 caagtcagaa atgggtgttc accgcttagt gcgaatctca ccatttgact ctgccaaacg
    16381 tcgccatacc tctttcacat ctgtagaagt gatgccagaa ttggatgata ctattgaagt
    16441 ggaaatccgt gaagatgata tcaagatgga taccttccgt tcaggtggtg ccggtggaca
    16501 aaacgtcaat aaggtttcaa caggtgtacg tttaactcac attccaactg gaattgttgt
    16561 ccaatcaaca gtggatcgta cccagtatgg aaatagagat cgtgccatga agatgttgca
    16621 ggctaagctc tatcaaatgg agcaagagaa gaaggctgcg gaggtagatt ctctcaaagg
    16681 tgagaaaaag gagatcactt ggggaagcca aatccgttct tatgtcttca cgccttatac
    16741 tatggtaaaa gatcaccgaa ctagctttga ggttgctcag gtagataagg ttatggatgg
    16801 ggatctagat ggttttatcg atgcttatct caagtggcga attagctaag atagaaagga
    16861 actcacatgt caattattga aatgagagat gtcgttaaaa aatacgacaa cggaacaact
    16921 gctctacgcg gtgtttcggt cagcgttcaa ccgggggaat ttgcttacat cgtaggacct
    16981 tcaggagcag ggaagtcaac ttttattcgt tctctgtatc gtgaagtaaa aatcgataaa
    17041 ggaagcctat cagttgctgg ttttaatctg gttaagatca aaaagaaaga tgtcccgctt
    17101 ctacgtcgta gtgttggggt tgtcttccag gattataaat tgttaccaaa gaaaactgtc
    17161 tatgaaaata ttgcttacgc tatggaagta atcggggaaa atcgccgtaa tatcaaaaga
    17221 cgagtgatgg aagttttgga cttggttgga ttgaagcata aggttcgttc tttcccaaat
    17281 gaactctcag gtggggagca acagcggatt gcgattgcgc gtgcaattgt aaataatccc
    17341 aaagtattga tagctgatga gccaacagga aatctggatc cggataattc atgggaaatt
    17401 atgaatctct tggaacggat taacctacaa ggaacaacta ttttgatggc gactcataat
    17461 agccagattg taaatacctt gcgccaccgt gtcattgcca ttgaaaatgg ccgtgtcgtt
    17521 cgtgacgaat caaaaggaga gtatggatac gatgattagt agattttttc gccatttatt
    17581 tgaagcctta aaaagtttga aacgaaatgg ttggatgaca gtagctgctg tcagttcagt
    17641 catgattact ttgaccttgg tggcaatatt tgcatctgtt attttcaata cagcgaaact
    17701 agctacagat attgaaaata atgtccgtgt agtagtttat atccgaaagg atgtggaaga
    17761 taatagtcag acaattgaaa aagaaggtca aactgttaca aataatgact accacaaggt
    17821 atatgattct ttgaagaaca tgtctacggt taaaagtgtt accttttcaa gtaaagaaga
    17881 acaatatgaa aaattaaccg agataatggg agataactgg aaaatctttg aaggagatgc
    17941 caatcctctc tatgatgcct atattgtaga ggcaaacact ccaaatgatg taaaaactat
    18001 agccgaagat gctaaaaaaa ttgaaggtgt ctctgaggtt caagatggcg gtgccaatac
    18061 agaaaaactc ttcaagttag cttcatttat ccgtgtttgg ggactaggga ttgctgcttt
    18121 gttaattttt atcgcagttt tcttgatttc aaataccatt cgtattacca ttatttcccg
    18181 cagtcgcgaa attcaaatca tgcgcttggt cggagctaaa aacagttata tccgtggacc
    18241 gttcttgtta gaaggagcct ttatcggttt attgggagct atcgcaccat ctgttttggt
    18301 ctttattgtt tatcaaattg tttaccaatc tgtcaacaaa tcgttggtag ggcaaaatct
    18361 atccatgatt agtccagatt tatttagtcc gttgatgatt gccctactat ttgtgattgg
    18421 ggttttcatt ggttcattgg gatcaggaat atccatgcgc cgattcttga agatttaggt
    18481 aaaatagctg cttttatgag gagattgtaa aatctccttt tttgctacaa gagtttttga
    18541 aaagagatgc gcagaagaaa agagcttcca aagaagtccc ccagagaaga cttcttgatg
    18601 gctaatttga acttgaaatt tggcgcacta gaaatttttt agaaaaaagt gtaatttttt
    18661 tataaaagcc tttacaaaaa aaattaaagt ggtataatta aatcatagaa agtgcaaacg
    18721 ttttcgtaaa acgtttgcct aaataaaaat aaaggagatt tgaatgatga aagatacatt
    18781 caaaaatgtc ttgtctttcg aattttggca aaaattcggt aaggctttga tggtagttat
    18841 cgcggttatg ccggctgctg gtttgatgat ttcaatcggt aagtctatcg tgatgattaa
    18901 cccaatcttt gcaccacttg tcatcacagg tggaattctt gagcaaatcg gttggggggt
    18961 tatcggtaac cttcacattt tgtttgccct agccattgga ggaagctggg ctaaagaacg
    19021 tgctggtggt gctttcgccg ctggtcttgc cttcatcttg attaaccgta tcactggtac
    19081 aatttttggt gtatcaggcg atatgttgaa aaatccagat gctatggtaa ctactttctt
    19141 tggtggttca atcaaagttg ctgattactt tatcagtgtt cttgaagctc cagccttgaa
    19201 catgggggta ttcgtaggga ttatctcagg ttttgtaggg gcaactgctt acaacaaata
    19261 ctacaacttc cgtaaacttc ctgatgcact ttcattcttc aacgggaaac gtttcgtacc
    19321 atttgtagtt attcttcgtt cggcaatcgc tgcaattcta cttgctgctt tctggccagt
    19381 agttcaaaca ggtatcaata acttcggtat ctggattgcc aactcacaag aaactgctcc
    19441 aattcttgca ccattcttgt atggtacttt ggaacgtttg ctcttgccat ttggtcttca
    19501 ccacatgttg actatcccaa tgaactacac agctcttggt ggtacttatg acattttaac
    19561 tggtgcagct aaaggtactc aagtattcgg tcaagaccca ctatggcttg catgggtaac
    19621 agaccttgta aaccttaaag gtactgatgc tagtcaatac caacacttgt tagatacagt
    19681 acatccagct cgtttcaaag ttggacaaat gatcggttca ttcggtatct tgatgggtgt
    19741 gattgttgct atctaccgta atgttgatgc tgacaagaaa cataaataca aaggtatgat
    19801 gattgcaaca gctcttgcaa cattcttgac aggggttact gaaccaatcg aatacatgtt
    19861 catgttcatc gcaacaccta tgtatcttgt ttactcactt gttcaaggtg ctgccttcgc
    19921 tatggctgac gtcgtaaacc tacgtatgca ctcattcggt tcaatcgagt tcttgactcg
    19981 tacacctatt gcaatcagtg ctggtattgg tatggatatc gttaacttcg tttgggtaac
    20041 tgttctcttt gctgtaatca tgtactttat cgcaaacttc atgattcaaa aattcaacta
    20101 cgcaactcca gggcgcaacg gaaactacga aactgctgaa ggttcagaag aaaccagcag
    20161 tgaagtgaaa gttgcagcag gctctcaagc tgtaaacatt atcaaccttc ttggtggacg
    20221 tgtaaacatc gttgatgttg acgcatgtat gactcgtctt cgtgtaactg ttaaagatgc
    20281 agataaagta ggaaatgcag agcaatggaa agcagaagga gctatgggtc ttgtcatgaa
    20341 aggacaaggg gttcaagcta tctacggtcc aaaagctgac attttgaaat ctgatatcca
    20401 agatatcctt gattcaggtg aaatcattcc tgaaactctt ccaagccaaa tgactgaagc
    20461 acaacaaaac actgttcact tcaaagatct tactgaggaa gtttactcag tagcagacgg
    20521 tcaagttgtt gctttggaac aagtaaagga tccagtattt gctcaaaaaa tgatgggtga
    20581 tggatttgca gtagaacctg caaatggaaa cattgtatct ccagtttcag gtactgtatc
    20641 aagcatcttc ccaacaaaac atgcttttgg tattgtgacg gaagcaggtc ttgaagtatt
    20701 ggttcacatt ggtttggaca cagtaagtct tgaaggtaaa ccatttacag ttcatgttgc
    20761 tgaaggacaa aaagttacag caggagatct ccttgtcaca gctgacttgg atgctatccg
    20821 tgcagcagga cgtgaaactt caacagtagt tgtcttcaca aatggtgatg caattaaatc
    20881 agttaaatta gaaaaaacag gttctcttgc agctaaaaca gcagttgcta aagtagaatt
    20941 gtaatatact tgaggttgga agctgtattc caacctctta ttttgggaga aaagaatgaa
    21001 atttttaaca ctcaatactc acagttggat ggagaaagaa gcagaggaaa aattccagat
    21061 tttgcttgaa gatattcttg aaaaggacta tgatttgatt tgtttccaag aaatcaatca
    21121 ggagatgacc tcgtcagagg tggaggttaa tgacctttat caagctttgc cagcagctga
    21181 gcctattcac caagaccatt atgttagact cttggttgaa aagttgttag agcaagggaa
    21241 aaattactac tggacctggg cttataacca tatcggctat gaccgctacc atgaaggtgt
    21301 ggctatcttg tctaaaacac ctattgaagc cagagaaatt ttggtttcag atgtggatga
    21361 tccaacagac tatcatactc gccgtgttgc cctagctgaa actgtagtcg atggcaagga
    21421 gctagcagtt gccagtgttc atctctcttg gtgggataaa ggtttccaag aagaatgggc
    21481 acgatttgag gctgtcttga aaaaattgaa caagccactt ttactagctg gagattttaa
    21541 caacccagca ggtcaggaag gttaccaagc tattttagct agtccattag gcttacaaga
    21601 cgcatttgaa gttgctcaag agaaaagtgg tagctatact gttccgcctg aaattgatgg
    21661 ctggaaaggg aacactgaac cccttcgaat cgattatgtc tttactacca aagagttagc
    21721 ggtggaaaat ttacatgtcg tatttgatgg taacaagagt ccacaagtga gtgatcacta
    21781 tggcttgaat gctatattaa actggaaata ataactgaaa agaggttgga actataaaat
    21841 tccagccttt tcttactaga gaagctactg gaaatagcct aaataagtga gactactgta
    21901 atggaataaa atatggtata attgataagg tagatagaat cgaggatgtt atgtcattta
    21961 cgaaatttca atttaaaaac tatattagag aagccttgaa ggagttaaaa tttacaactc
    22021 caacagaggt gcaagacaag ttgattccta ttgttttggc aggtcgtgac ctagtaggag
    22081 aatcaaaaac aggttcaggt aagactcata ctttcttgtt accgattttc cagcaattag
    22141 atgaagctag cgatagtgta caagcagtga ttactgcacc gagtcgtgag ttggctactc
    22201 aaatttacca agtagcgcgt cagatttcag ctcactcaga tgtcgaagtt cgtgtggtta
    22261 attatgtggg tggtacggat aaggctcgcc agattgagaa attggcaagc aatcagcctc
    22321 atattgttat tggaacacca ggccgtatct acgacttggt taaatctggt gatttagcta
    22381 ttcataaagc caagacattt gttgttgatg aagcagatat gaccttggat atgggattct
    22441 tggaaactgt tgataagatt gctggcagtc ttccaaaaga cttgcaattc atggtcttct
    22501 cagcgactat cccacaaaaa ctgcaaccat tcttgaaaaa atacttatca aatcctgtta
    22561 tggagaaaat taagaccaaa acggttattt ctgacaccat tgataattgg ttgatttcga
    22621 ccaagggaca tgataagaat gctcaaattt accagttgac tcagttgatg cagccgtatt
    22681 tggcaatgat ttttgttaac actaaaacgc gtgctgatga attgcattca tatctgactg
    22741 ctcaaggctt gaaggttgca aaaatccatg gcgatattgc ccctcgtgaa cgcaagcgaa
    22801 tcatgaatca ggtgcaaaat ctggattttg agtatattgt cgcaacagat ttggcagcgc
    22861 gtgggattga cattgaaggt gtcagccatg tcatcaatga tgccattccg caagacttat
    22921 ctttttttgt tcatcgtgtt ggtcgtactg gacgaaatgg cctaccaggt acagctatta
    22981 ccctttatca gccaagtgat gactcggata tccgtgagtt ggagaaattg ggaatcaagt
    23041 ttagtcctaa gatggtcaaa gacggggaat ttcaagatac ctatgaccgt gatcgtcgtg
    23101 ccaaccgtga gaaaaaacaa gataaacttg atatcgaaat gattggtttg gttaaaaaga
    23161 aaaagaaaaa agtcaaaccg ggttataaga agaaaattca atgggcggtt gatgaaaagc
    23221 gccgtaaaac caagcgtgct gaaaatcgcg ctcgcggtcg tgcagagcgt aaagctaaac
    23281 gccaaacatt ttaatagaaa ttgttggagt attgagctcc aactttttgc tttatgagaa
    23341 cgaactatct aaaccgaaac actacattaa agactgcaaa ttgcgattaa aaatggtata
    23401 atgataaagt tatatagtcc cgataagatg gtaggtattt attacgaaga gttttcctat
    23461 cagtactttg taactctata acaatatttt ttaagggggg acatttttat gtcagagcgt
    23521 aaattattca cgtctgaatc tgtatctgag gggcatccgg ataagattgc agaccaaatt
    23581 tcagatgcga ttttggatgc tattttagca aaggatccag aggcgcacgt tgctgctgaa
    23641 acagctgtat atactggttc tgtccacgtt tttggtgaaa tttctacaaa tgcctatgtg
    23701 gatattaacc gtgtggttcg tgataccatt gcagagattg gttataccaa tacagaatat
    23761 ggattttctg ctgagacggt gggagtacac ccatctttgg tggaacaatc tcctgacatc
    23821 gctcaaggtg ttaacgaagc cttggaggtt cgtggaaatg ctgatcaaga tccactggac
    23881 ttgattggag caggtgacca agggctcatg tttggatttg cagtagatga aacagaagag
    23941 cttatgccat tgccaattgc actcagtcat aaattggttc gtcgtctggc agaacttcgt
    24001 aagtctggag aaattagcta tctccgtcca gatgcaaaat cacaagttac agttgagtac
    24061 gatgaaaatg accgtccggt acgtgtagat acagtcgtta tttctactca gcatgatcca
    24121 gaggccacta atgaacaaat ccatcaagat gtgattgaca aggtcatcaa agaagttatt
    24181 ccatcttctt atcttgatga taagacaaaa ttctttatca atccgacagg tcgttttgta
    24241 atcggtggtc ctcaagggga ctcaggtttg actggtcgta agattattgt agatacttat
    24301 ggtggctact ctcgtcatgg tggtggtgcc ttctctggta aagatgcgac taaggtggat
    24361 cgttcagcct cttatgcggc tcgctatatt gccaagaata tcgttgcagc agaccttgct
    24421 aagaaggcag aagtgcagtt ggcctatgct atcggtgttg cgcaacctgt ttctgttcgt
    24481 atcgatactt tcggtacagg aacagtagct gaaagtcaac ttgaaaaagc ggctcgtcaa
    24541 atctttgacc ttcgccctgc agggattatc caaatgctgg acctcaagcg tccaatttac
    24601 cgtcaaacat cggcttacgg tcacatggga cgtacagata ttgatcttcc atgggaacgt
    24661 ttggataagg tagatgcttt gaaagaagca gtaaaataag attttaagag gggaacgtcc
    24721 tctctttttt atagttttta actatactgg gatactgttc tgaaaatcca ttttgcgaaa
    24781 gtagagattt acggcttttt gtcaactgta gtgggttgaa gaaaagctaa gcttgagaaa
    24841 ggacaaattt cgtcctttct tttttgatgt tcagagcgat aaaaatccgt tttttgaagt
    24901 tttcaaagtt tcgaaaacca aaggcattgc gtttgataag tttgatgaga ttattggtcg
    24961 cttccaattt ggcgtttgaa tagggtagtt gaagggcgtt gacgattttc tctttgttct
    25021 ttagaaaggt tttaaagaca gtctgaaaaa taggatgaac ctgcttcaga ttgtcctcaa
    25081 tgagtccgaa aaatttctca gggtctt
//
LOCUS       DBERXF010000034        25043 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.34, whole genome shotgun sequence.
ACCESSION   DBERXF010000034 DBERXF010000000
VERSION     DBERXF010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25043
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.34"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(172..3348)
                     /gene="carB"
                     /locus_tag="ACL8JK_001518"
     CDS             complement(172..3348)
                     /gene="carB"
                     /locus_tag="ACL8JK_001518"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGS1786379.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEVPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(3660..4739)
                     /locus_tag="ACL8JK_001519"
     CDS             complement(3660..4739)
                     /locus_tag="ACL8JK_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGS1786380.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(4789..5712)
                     /locus_tag="ACL8JK_001520"
     CDS             complement(4789..5712)
                     /locus_tag="ACL8JK_001520"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGS1786381.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(5731..6252)
                     /gene="pyrR"
                     /locus_tag="ACL8JK_001521"
     CDS             complement(5731..6252)
                     /gene="pyrR"
                     /locus_tag="ACL8JK_001521"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGS1786382.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(6463..7092)
                     /gene="nth"
                     /locus_tag="ACL8JK_001522"
     CDS             complement(6463..7092)
                     /gene="nth"
                     /locus_tag="ACL8JK_001522"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGS1786383.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(7092..7634)
                     /locus_tag="ACL8JK_001523"
     CDS             complement(7092..7634)
                     /locus_tag="ACL8JK_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGS1786384.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFASLQGLFDGDE"
     gene            7804..8121
                     /locus_tag="ACL8JK_001524"
     CDS             7804..8121
                     /locus_tag="ACL8JK_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGS1786385.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNNQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            8360..9919
                     /locus_tag="ACL8JK_001525"
     CDS             8360..9919
                     /locus_tag="ACL8JK_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS1786386.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(9963..10862)
                     /gene="htpX"
                     /locus_tag="ACL8JK_001526"
     CDS             complement(9963..10862)
                     /gene="htpX"
                     /locus_tag="ACL8JK_001526"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HGS1786387.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(10864..11424)
                     /locus_tag="ACL8JK_001527"
     CDS             complement(10864..11424)
                     /locus_tag="ACL8JK_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HGS1786388.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            11518..12231
                     /gene="rsmG"
                     /locus_tag="ACL8JK_001528"
     CDS             11518..12231
                     /gene="rsmG"
                     /locus_tag="ACL8JK_001528"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGS1786389.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12534..13817
                     /locus_tag="ACL8JK_001529"
     CDS             12534..13817
                     /locus_tag="ACL8JK_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGS1786390.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(14012..15583)
                     /gene="ffh"
                     /locus_tag="ACL8JK_001530"
     CDS             complement(14012..15583)
                     /gene="ffh"
                     /locus_tag="ACL8JK_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGS1786391.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(15595..15927)
                     /locus_tag="ACL8JK_001531"
     CDS             complement(15595..15927)
                     /locus_tag="ACL8JK_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGS1786392.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            complement(16017..16394)
                     /locus_tag="ACL8JK_001532"
     CDS             complement(16017..16394)
                     /locus_tag="ACL8JK_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGS1786393.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSRYQVDGQKIE
                     LAYQLQNQEGHPFASYQLEITWG"
     gene            16466..17770
                     /locus_tag="ACL8JK_001533"
     CDS             16466..17770
                     /locus_tag="ACL8JK_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGS1786394.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSLIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            17783..18589
                     /gene="yidA"
                     /locus_tag="ACL8JK_001534"
     CDS             17783..18589
                     /gene="yidA"
                     /locus_tag="ACL8JK_001534"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGS1786395.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            18632..19630
                     /locus_tag="ACL8JK_001535"
     CDS             18632..19630
                     /locus_tag="ACL8JK_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005634 - nucleus [Evidence IEA];
                     GO_function: GO:0003712 - transcription coregulator
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HGS1786396.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDITMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(19797..19868)
                     /locus_tag="ACL8JK_001536"
     tRNA            complement(19797..19868)
                     /locus_tag="ACL8JK_001536"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19833..19835),aa:Arg,seq:cct)
     gene            complement(19910..20257)
                     /gene="rplS"
                     /locus_tag="ACL8JK_001537"
     CDS             complement(19910..20257)
                     /gene="rplS"
                     /locus_tag="ACL8JK_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGS1786397.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(20376..20705)
                     /gene="crcB"
                     /locus_tag="ACL8JK_001538"
     CDS             complement(20376..20705)
                     /gene="crcB"
                     /locus_tag="ACL8JK_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGS1786398.1"
                     /translation="MVIVYLAIACGFGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(20699..21073)
                     /gene="crcB"
                     /locus_tag="ACL8JK_001539"
     CDS             complement(20699..21073)
                     /gene="crcB"
                     /locus_tag="ACL8JK_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGS1786399.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFVVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(21070..21336)
                     /locus_tag="ACL8JK_001540"
     CDS             complement(21070..21336)
                     /locus_tag="ACL8JK_001540"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGS1786400.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(21452..21895)
                     /locus_tag="ACL8JK_001541"
     CDS             complement(21452..21895)
                     /locus_tag="ACL8JK_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGS1786401.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRIFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVV"
     gene            21999..22934
                     /locus_tag="ACL8JK_001542"
     CDS             21999..22934
                     /locus_tag="ACL8JK_001542"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGS1786402.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            23030..23272
                     /locus_tag="ACL8JK_001543"
     CDS             23030..23272
                     /locus_tag="ACL8JK_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGS1786403.1"
                     /translation="MKKDIHPEYRPVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(23329..23907)
                     /locus_tag="ACL8JK_001544"
     CDS             complement(23329..23907)
                     /locus_tag="ACL8JK_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HGS1786404.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKA
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSTAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(23882..24893)
                     /locus_tag="ACL8JK_001545"
                     /pseudo
     CDS             complement(23882..24893)
                     /locus_tag="ACL8JK_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            complement(24896..25043)
                     /locus_tag="ACL8JK_001546"
                     /pseudo
     CDS             complement(24896..25043)
                     /locus_tag="ACL8JK_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         7478 a         5554 c         4690 g         7321 t
ORIGIN      
        1 tttttgaaaa atcttgatat gatgcgtttt ataattttaa agactttttt ctatagtaga
       61 ttgaaataag atgcgaacaa atcaattaga aaattcaaat taatttctag aaatatttta
      121 gtatccctgt gtactgttct aaattcagtc tgctatacct tatttttcta tttaaatcgc
      181 ttctgtaaca aagctacgac tttcaagtac cttaagcatg gcattagctg tatctagcgc
      241 tgtgaagagg ggcaccccgt gttcaatggc tgaacgacga atttgctcac catcttcgtc
      301 agcagttcgt tttgttccta ctgtgttaat gatagcttga attcttcctt tgcgtacaaa
      361 acttgggata tccttatcgt catcaccaat cttaccaaca ggttgggctt gcaagccatg
      421 actagcaaag aaggctgctg tcccttctgt cgcaaggatt ccataaccaa tgttttggaa
      481 acgacgagcc aagttcaagg cttcttcttt ggcatcatca gcgatggtaa agacgacatt
      541 accaaaagtt ggcaagtgta gataagaagc ttcaaaggct ttatagagag ctttttccaa
      601 agtagcatca gaacccataa cttcacctgt tgacttcatt tcaggaccga gcaagctgtc
      661 taccttagct agtttggtaa aggagaagac aggtgccttg atatgaacac gggtgctttc
      721 agggtaaagt ccattttggt agccaagttc tgataaactt tgaccaagaa tgagcttggt
      781 cgctacttga gccataggaa tattggttac cttagatagg aatggaacgg tacggctggc
      841 acgtggattg acctcaataa cgtagacttt ttcatccttg ataacaaact ggatgttcat
      901 cattccaagg cagtgaagac cgattgctaa gcgtttggtg tagtctgcga tggtctcctg
      961 aaccttttgc gacaaggttt gtggtgggta aacagccatt gagtcacctg agtggacacc
     1021 agcacgttcg atatgctcca tgataccagg aatgagtaca tttttaccat ctgaaatggc
     1081 atcaacttcg cactcttgcc caacgatata agagtcgaca agaactggat ggtctggact
     1141 agccttaaca gcagttcgca tgtaagaacg aaggtcttct tcgttttcaa cgatttccat
     1201 ggcacgtcca ccaagtacat aagatgggcg gacaagaact gggaagccaa tcttacgagc
     1261 tgcaagagct gcttcttctt cattggtagc cgtttgtcct ggtggctgtg gaatatccaa
     1321 ttctttgaga gcttgctcga agaggtcacg gtcttcggca cggtctaggt cagcaacctg
     1381 tgtaccaagg atggtcacac ctgcttttgc caatggctcc gcaaggttga tggctgtttg
     1441 accaccgaac tgaacgataa ctccctttgg ttgttccaag tcaatgacgt tcataacatc
     1501 ttcgaatgtc aatggctcaa agtaaagctt atctgataca gagaagtctg ttgaaacggt
     1561 ctctgggttt gagttcatga tgatagcttc ataaccagct gcctggatag ccttaacaga
     1621 gtgaacggtt gcgtagtcaa actcaacccc ttgaccgata cggattggac ctgaacctag
     1681 gacaagtaca gattctttat cagatctgat agattcattt tcccaaccat aggttgaata
     1741 gaaatatggc gtttcggagt cgaactctgc cgcacaagta tctaccatct tatagactgg
     1801 gacaatcttg ttttccaaac gaagttggcg aactttatca tcagtcgttc cccagagttc
     1861 agcaatctta cggtctgaaa aaccattaag tttggctgtt ttcaaaactt ctagatcttg
     1921 tggatgagca cccaattctt gctcaatttc aaagatatgc aagagtttat caagatagaa
     1981 gatatcaatt tttgtaagct ctgcaatttc ttcaggtgtg tagccacgac gaattgcttc
     2041 tgatacgtag aagagacggt catcttgggc tttgacaacc ttttcaatca aggcatcatc
     2101 agaaactgct gcaagttcag gtacttcatt gtggtgcacc ccaatttcaa gggatcggca
     2161 ggccttgaga agagattcct cgatgttacg accgattgcc atgacttctc cagtcgcctt
     2221 catttgtgta ccgagacggc gttcaccctt ttcaaacttg tcaaatggga aacgtggaat
     2281 cttagcaact acgtagtcaa gggctggttc aaacatggca taggttgaac ctgtaactgg
     2341 gtttataacc tcatccaagg tcaaacctac tgcaatcttg gcagccaact tagcaatcgg
     2401 atatcctgtc gctttagaag caagggctga cgaacgtgat acacgagggt ttacttcgat
     2461 aacataatac ttgaagctgt taggatcaag agctagctga acattacatc caccttcaat
     2521 cttgagggcg cgaataatgc tcaagctcgc atcacgaagc atttggtttt catagtctga
     2581 catggtttgc gcaggggcaa atacaatgga atcccctgtg tgaatcccaa ctgggtcaaa
     2641 gttttccatg ttacaaacaa ccaaggcatt gtcagctgag tcacgcatca cttcgtattc
     2701 aatttccttg aaaccggcaa tcgaacgctc aatcaaacat tgggtaacag gtgacaattt
     2761 caaaccattt tcagtgattt cacgcaattc tttttcgttg gcacacatac caccaccagt
     2821 accaccaagg gtaaaggctg gacgaacgat gactgggtag ccaattgtcg ctgcaaaggc
     2881 aactgcttct tctactgtgt taacaatttc agattctgga atgggttgct caagctcttc
     2941 catcaattgt ttaaagaggt cacggtcctc cgcttggtca atggcagata atttggtacc
     3001 cagaagttca acgccaagct cgtctaggat accattttta gataattcca tggccatgtt
     3061 gagacctgtc tgaccaccga gtgttggtag caaggcatct ggaccttcct tacgaagaat
     3121 acgtgtcaca aactcaagtg taatcggttc aatgtaaacc ttgtcagcaa tttccttgtc
     3181 cgtcatgatg gttgcaggat ttgagttaac caaaacaacc tcataacctt cctctttcaa
     3241 cgacaagcaa gcctgagtcc cagcgtagtc aaactcagca gcctgaccaa taataatcgg
     3301 accagaacca atcaccataa ttttttgaat atcagtacgt ttaggcatag tttatgatac
     3361 aaagcccgta aagaacacag tgaaaatagg aaactcggcg cagacgcctt cagcgtcaag
     3421 acgatgttta tctttttcac acagttctta gggcgtgttc acttccgcga acaatgtatc
     3481 ttctcctttc tattcgtcgc ctctcagggc gacattaaat aagatacaaa ggacgaatag
     3541 aaagcgattg aattttagga aatcaaggaa ggattgacaa tccaagttgg tttctctaca
     3601 ttctgagctt tccgtccgtg ttcagttaca taaattctcc gacgagcttt tactcgttct
     3661 tagtttgatt gtttaaaaac ttccatcatc tcgataaact cgtcaaatag gtagctagcg
     3721 tcgtgtggcc caggagctgc atctgggtgg tattgaacag agaaagcagg ttggtatctg
     3781 tggcgcacac cttccactga cttgtcattg atttcttcgt gggtaataat caagtgctct
     3841 ggcaaatcct cgcggctgac tgcataacca tggttctggc tggtgaagtc tactcgtcct
     3901 gttgcgattt cacgtaccgc atggttgaat ccacggtggc caaacttcat cttataggtc
     3961 ttagccccgt ttgccattgc aaagagttgg tgtcccatac aaataccaaa gattggaatt
     4021 tttccttgta caccgcgaat catgtcgagt gcttgtggaa cgtcttctgg gttacctgga
     4081 ccatttgaca acataactcc gtcaggattg agatggagaa tttcttcagc cgttgtcgaa
     4141 taaggaacaa ctgtcacgtt acagttgcgt ttagaaagtt cacgtaggat tgagtgcttg
     4201 agaccaaagt ccactagcac cacgctcaaa ccaactcctg gagctggata agacgtttta
     4261 gtagaaacct gtttgatatt gtctgtcggt aaaactgttg cttggagctg gtccgtcaca
     4321 tggtccatac tgtccccaac atgggtcaag gttgcacgca tagtaccatg cttacggata
     4381 atcttggtaa gagcacgcgt atcaattcct gaaatccctg gaattttctt ggctttcaaa
     4441 aattcatcca aggtcatttg gttgcgccag ttgctagctc tacgcgcttc ttcaaaaaca
     4501 acgactccct tacaagttgg aataatggat tcataatcat cacgattaat accataattt
     4561 cctaccaaag gataagtaaa ggtcaagatt tgtccattat aagactggtc tgtaatggat
     4621 tcttggtagc cggtcatccc tgtattaaag acgatttcgc ctgttacatc aatatctgct
     4681 ccgaaggcct tgccttcaaa aactgtgcca tcttctaata ctagaattct ttttgtcata
     4741 ttttcacctc tcgtggacgc tcactggcgt cttttaacgt cttgtgtttt agttggcgtt
     4801 tctactcgct agtacggatt ctaagattgc cattcgaaca aagacaccat tggtcatttg
     4861 ttggacaatc cgtgattttg gtgcttcaac caagtggtct gctatttcta catcacgatt
     4921 gattggagct gggtgcatga ggattgctgt ttctttcaaa cgatcgtaac gttcttgagt
     4981 caagccatgt tgggcatggt agtcttcttt tgaaaataca gctccactat catggcgttc
     5041 gtgttgcaca cggagaaaca tcatgacatc aacctgatca atgatttcat caatggttac
     5101 aaactgtcca tagtctgcaa actcttgact tctccattcc tcaggtccag cgaaaaagag
     5161 ttcagctccc aagcgtttca aaatctgcat attggatttg gcaacgcgtg agtggtccaa
     5221 gtcacctgca atagcaactt taagaccctc aaagtggcca aattcctcat aaatggtcat
     5281 caaatcaagc aagctctggc tagggtgttg gcccgaacca tctccaccat tgatgatgga
     5341 agtcgtaatc gttggactag caatcaattc tctatagtag tcgacctctg gatggcgaat
     5401 cacacagaca tccactccta aagcagacag agtcaaaatg gtgtcataaa gtgtctcacc
     5461 cttattaacc gagctagtct tcacatcaaa gtcaagtcgt tccaatccaa gtttaatctc
     5521 tgcgacttca aaggacttat gtgtccgtgt agaatcctca aagaagagat tggaaacaat
     5581 cggatggtct tcatagggaa gctgggctcc atttttaaac tcaattcctc gcttgatcaa
     5641 tttcattact tgatcgacag tgaggtcttc catggacacc acatggttca atgcttgttg
     5701 attttctgac atggctactc ctttaacttt ctaagcttct tcagtaatca gaactctgtc
     5761 ttggtcatca agttctgtca tctctacgat gatttcttca gaacgactgg ttgggatatt
     5821 ttttccaacg taatctggac ggattggcaa ttctctatgt ccacgatcga ctagaactgc
     5881 taaactcaca cgcgcaggac gaccatgacc gacaatatta tcaatagcag cacggatggt
     5941 acgacctgta tagagcacat catccaccaa gataacttcg cggtctgtca catcgacaga
     6001 aaccaaagaa gtatcttctc cacttttaac atcatcacgg aaaggtttag tatccaattc
     6061 cacaacagga actgaaagat tttctaactg cttcaaacgt tcttggattc ggtgggcaat
     6121 aaagacacca cgagttttaa taccagccaa gacgatctta ttcaaatctt tgttgcgttc
     6181 gataatctca taagtaatac gcgtaatcgc tcgtttgacg gtcaattcgt ctacaacttc
     6241 ttttgttttc atgacaaacc tccaaaaaga aaagtctcct taaacaagga gacttgaaat
     6301 ttatagccaa gcgagcccta ctgcacacag tatagacttc acccttctac tttatcgcgc
     6361 tccttgcctg cctcacggga caggtttaaa ggaatattta gttatcattt actatagcac
     6421 aaagcatgct taaaatcaag caaaaagttt caatgtagca tcttacaaat tgctaaaatc
     6481 atataattgt gggtactgat cacactctgg attttttgga tggcaaatgg ctcttccaaa
     6541 ataaatcatg gcctgatggg cagctaacca ctgctcaggc ggcaagatat ccatgacccg
     6601 cttttccacc tcaagtggcg tcgctgattt tttgacaata tcgtggtgtt tgcaaatacg
     6661 ctccacatga gtatccactg caaaggctgg aatcccaaat cctacactca tgacaacatt
     6721 ggctgtcttg cgaccaacac ctgccaaact ctccaattct tcacgtgtct gagggacttg
     6781 accatcaaaa tcgtctagta actgttgggc acatttttta aggaatttag ctttattccg
     6841 atacaatccc aagcgagaaa tatgtgaagc aatctcactc tctgtcgcta cagacatagc
     6901 ttggggtgtt ggaaaggcaa caaagagacc tggtgtggcc ttatttaccg ctgcatctgt
     6961 cgtctgggct gataacatga ccgcaaccag gagttcaaaa tgattggtaa aatcaagact
     7021 aggcttggca tctgggaaga gggcaatgat ttcttctagc acctttcgtg ctcgtttttt
     7081 tgacaagacc attattcatc tccgtcaaat agtccttgta agctagcaaa aggactgttt
     7141 tcttctttct ttactgcttg ttgagcttgg tattcttcct ctgtcatgat ttgccagtca
     7201 tttcctgaga caaatccttg accagcttct tcttcagccg tcaagacctt gataggaatg
     7261 tttagcagga tattgtctga tacactctca gcaaggtcaa gcgccccatt ttcgatgggc
     7321 aagaccaagt catcatctaa aatttcttga tttagatggt tagttgcgcc ttccatgaaa
     7381 acttccgtga ctggataaga ttcaactaac tcaactggct ccatactgcg actcgaagca
     7441 agaacaatgg tataagatag ttgataatct aagaaataca tacggtcttc atattgtact
     7501 ttcccaactg caaggatatc ttttacatct aaaatttctt gattacgtgc acgcaggtca
     7561 tcaactaaat ctaacgtttg ttcaaagttc aaaccttcag actgcttacg aatttcttga
     7621 atatttaatt tcatacttcc tccataaaga tttactctct tgattatacc atgaaaaggc
     7681 tacaaatcag cacaccaaac tttgtaatta aaattcaaaa ttttaacata tttaccatga
     7741 tagttttgtt ttttagtgct atactatagg gaaagagtac atcagatcaa ggaggatgct
     7801 cacatggaag acaagaaact cattcaactc ctatccaagt taaataaaag ctaccaaaac
     7861 tgtaaacagg gtacggcaga tgatattcga ctacaagagc tgctaaacac tactatgcaa
     7921 gagctcaaaa aaacggaaaa gttgaacaac agtatcttaa ttgatcttga gaaattttac
     7981 caacccacca gtcctctgat tggactgggt agcctaaaac taaacaatca agcacgcact
     8041 gcttggcgaa actatgataa aatccattac gagcatgtca aacacgtact aagtctctat
     8101 ggacctgttt ttggatttta gagcatagaa tttccagttt tctgttgaca aaatttcctt
     8161 aaaggtatag tataaagata ctaatactcg gaggtaaggg agacatgaac aactaagtct
     8221 atcaaataaa gaacctttat ttagtagatc ttgtttttgt ctctttttgt gtgctctttt
     8281 atgctctttt tctggcatgt taatagagtt tttttgacat agactttggg ctctactagg
     8341 taaagtagag ctttttgtta tgcactatga acattctaga aagggaaatc atatgataaa
     8401 aatcaatcat ctaaccatca cacaaaacaa agatttacga gatcttgtat ctgacctaac
     8461 catgaccatc caagacgggg aaaaggttgc tattattggt gaagaaggaa atggcaaatc
     8521 aaccttactt aaaattttaa tgggggaagc tttgtctgat ttcactatca agggaaacat
     8581 ccaatctgac tatcagtcac tggcctacat tcctcaaaaa gtccctgagg acctaaaaaa
     8641 gaaaacttta cacgactact tctttttaga ttctattgat ttagactaca gtatcctcta
     8701 tcgtttggcg gaggaattgc attttgatag caatcgtttc gcaagtgacc aagagattgg
     8761 caatctatca gggggcgaag ctttgaaaat tcagcttatc catgagttag ccaaaccctt
     8821 tgagattcta tttttagatg aaccttcaaa tgacctagac cttgagacag ttgattggct
     8881 aaaaggccag attcaaaaga ccaggcaaac cgttattttc atttcccatg atgaagactt
     8941 tctttctgaa acggcagaca ctattgttca cttgcgactg gtcaaacacc gtaaagaagc
     9001 ggaaacgcta gtagagcatt tagactatga tagctatagt gagcagagaa aggctaattt
     9061 tgccaaacaa agtcagcaag ctgctaacaa ccaaagagcc tacgataaaa ccatggaaaa
     9121 acatcggaga gttaagcaaa atgtagaaac tgcgcttcga gctaccaaag atagtactgc
     9181 cggtcgccta ttggctaaaa agatgaaaac tgtcctctca caagaaaaac gctacgaaaa
     9241 ggcagctcag tccatgactc aaaagccact tgaagaggaa caaatccaac ttttcttttc
     9301 agacatccaa ccattaccag cttctaaagt cttagtccaa ctggaaaaag aaaatttgtc
     9361 cattgacgac cgagttttgg ttcaaaaact acaactaact gtccgtggcc aagaaaaaat
     9421 cggtattatc gggccaaatg gtgttgggaa atcaactctg ttagccaagt tacagagact
     9481 tctgaatgat aaaagagaga tttcacttgg ttttatgcca caagattacc acaaaaaact
     9541 gcaattggat ttatccccaa tagcctatct cagtaaaact ggggaaaaag aggaactaca
     9601 gaaaatccaa tctcacctag ctagtctcaa tttcagttat ccagaaatgc agcatcaaat
     9661 tcgctcctta tctggcggac aacagggaaa actcctgctt ttggatttag tcctgcgcaa
     9721 accaaacttt ctcctgctgg atgaacccac acgaaacttt tctcccactt ctcaacccca
     9781 aatcagaaaa ctctttgcta cctatccagg cggtctcatc actgtttcgc atgaccgtcg
     9841 tttcttaaaa gaagtctgct cgatcatcta tcgcatgaca gaacacggtt tgaagctagt
     9901 taatttagaa gatttataaa tttgcaacat agcaaaaatc cagagacgac ctctggattc
     9961 ttttacatct gttttaaacg ttcaatccgt tctgagatag gtgggtgggt ataaaagagt
    10021 ttttggaacc ccccaccttt cttaggatca ttgatataaa gggcactgct agcatcatcg
    10081 acgtggcgac tcataggttt gctattgtcc aacttatcta gggcattaat cattccctgg
    10141 ggattgcgag tcagctcgac actagatgca tctgccagaa attccctctg acgagaaata
    10201 gcgagctgaa ccaaggttgc agcgagaggt gccagtacaa tagctagtag ggaaaccact
    10261 agcataatga tttcaagacc atttccatct cggtcatcat cacttcgtct gcgacctgct
    10321 ccaccccacc acatcatacg acctgccata ctagaaagca tggtgatagc actagcaagg
    10381 gcaactgcaa tagtcgaaat acggatatca taattacgaa tatgactgac ttcatgtccc
    10441 ataacagctt ctagttcttc acgattcatg atagctagta gacctgaagt cgcagcaaca
    10501 gccgcatttt gaggattaga acctgtcgca aaggcattta aggctggatc atcaatgatg
    10561 aaaacacggg gcataggaat ctgagcgacc agagccatat cttccactac atggtagagg
    10621 tctggtgccg tttgctcatc cacctcacgc gctccattca tggacatgac aatctctgtc
    10681 gattgaaaaa tcatagacaa agcgtagata aagccgataa tcagtgcaat aaccaaacca
    10741 ccaagtccag atcttataaa gagataacca accgcataac caacaagagc taagagtagg
    10801 aaaaatacca gcaacaaaat ccaggttttt cgtttattgc ttgcaatttg atcaaacaac
    10861 atcttagtca cctaaaccgc taaaatcaac tttaggaacc gacttttcct cttcaggtgt
    10921 ttgaaggaaa tctgccgctt taaatccaaa cattccagcg ataatattgc tcgggaaagt
    10981 ttctaatttt acattgtagt tgctgacaac actgttatag agttgacgag agtaagaaat
    11041 tttattttct gtgtttgtca actcctcttg caatttaaca aagttagcac tagctttcaa
    11101 atctggatag ctttctgcaa ctgcaaaaat acctgaaacc tgacgagtga gggcatcact
    11161 ggctttcata gcttctgctg gtgaagtcgc tgccgccact tggttacgta gttctgccac
    11221 cttttcaagg gtagaacctt catatttggc ataacctttt acagtctcaa tcaagtttgg
    11281 caagaggtca tttcgacgtt tcaactgaac atcaatctga ctccaagcct ccttggtttg
    11341 catacgattt ttaaccaaac cgttatagct aacaatcaca aaaataacaa taagagcgat
    11401 aactccaaga ataatccaag tcataatata agtcctttct gcttttagat tagtaccagt
    11461 atatcaaatt ttctatgatt gtggtaaaat aagatgatac taaagaagga aataactatg
    11521 aaaccaaaaa cattttacaa cttgcttgcc gagcagaatc ttccactttc ggaccagcaa
    11581 aaagaacaat ttgaacgtta ttttgagctc ttggtcgagt ggaatgagaa gattaatttg
    11641 acggcgatta cggacaagga agaagtttat ctcaaacatt tttacgattc gattgcaccc
    11701 attcttcaag gtttgattcc caatgaaact atcaaacttc ttgatatcgg ggctggggca
    11761 ggatttccta gtctaccaat gaaaattctc tatccggagt tagatgtgac cattattgat
    11821 tcactcaata agcgcatcaa cttcctacaa ctcttggctc aagaactgga tttgaacgga
    11881 gttcatttct accacggacg tgccgaagat tttgcccaag acaagaactt ccgtgctcaa
    11941 tatgattttg taacagctcg tgcggttgcc cgtatgcagg tcctatctga attgaccatt
    12001 ccctacctta aggttggtgg aaaactattg gcactcaagg ccagcaatgc gcctgaggaa
    12061 ttattagaag ctaagaatgc cctcaatctc ctttttagta aggtcgaaga caatctcagc
    12121 tacgccctac cgaatagaga tccgcgctat atcacagtgg tagaaaagaa aaaagaaaca
    12181 ccaaataaat atccgcgtaa ggctggtatg ccaaataaac gcccacttta aattttttag
    12241 taaacaaatg tttacaaaat cagcctcgct cttttatttc taggctcggg aaaaaatgat
    12301 ttacaaaatc agcctcgctc ttttatttct aggctcggga aaaaatgatt tacaaaatca
    12361 tttttttctg ctatactatc ctaagcaaag gtttttaatg tcatcccgtg aggtgacgaa
    12421 gacgcagaaa tatttgaaac tctttaaaat ctaaatttta aagaagtctt actctgaggg
    12481 cctattgctg taaaataatg ggctcttttt tgatgcccaa aagtgaggtt tatatgaaac
    12541 aagaatcaac tgttgatttg ttactagacg ttgaccaacg tccttcggat ggaaaaggaa
    12601 ttctccttag cttccaacac gttttcgcca tgtttggtgc gaccatcttg gtaccattga
    12661 ttttgggaat gcctgtatct gttgcccttt ttgcttcagg tgttggaaca ctcatctaca
    12721 tgattgctac tggttttaaa gttccagttt atctaggttc ttcatttgcc tttatcacag
    12781 ctatgtcact ggctatgaaa gaaatggggg gggatgtatc tgctgcccaa acaggggtta
    12841 tcttgactgg tttggtctat gtccttgttg ctaccagcat ccgatttgta ggaacaaaat
    12901 ggattgataa actcttgcca ccaatcatta tcggtcctat gatcatcgtt atcggtcttg
    12961 gacttgcagg ttcagctgtt accaatgcag gtcttgtagc agacggaaat tggaaaaatg
    13021 ctctggtagc cgttgttact ttcctaattg ctgcctttat caatacaaaa ggaaaaggct
    13081 tcctacgaat cattccattc ctctttgcca ttatcggtgg ttaccttttc gcactaactc
    13141 ttggcttggt tgactttaca ccagttctta aagccaactg gttcgaaatt cctggtttct
    13201 acttgccatt tagcacaggt ggtgccttta aagagtacaa tctttacttt ggtccagaag
    13261 ccatcgctat cttgccaatc gctatcgtaa caatttctga acatatcgga gaccatactg
    13321 ttttgggtca aatctgtggt cgtcaattct taaaagaacc aggtcttcac cgtactcttc
    13381 ttggtgacgg tatcgcaact tctgtttctg ccttccttgg tggaccagcc aatacaactt
    13441 acggagaaaa tacaggggtt atcggtatga ctcgtatcgc ttctgtctca gttatccgta
    13501 acgctgcctt catcgcgatt gccctcagct tccttggtaa attcactgcc ttgatttcaa
    13561 ctattccaaa cgctgtactt ggtggtatgt caatccttct ctatggggtt atcgccagca
    13621 atggtttgaa agtcttgatt aaagaacgtg ttgatttcgc tcaaatgcga aacctcatca
    13681 tcgcaagtgc tatgttggtt cttggacttg gaggagctat ccttaaactt ggtccagtta
    13741 cactttcagg tactgccctt tcagccatga caggaatcat cttgaacttg atcttgccat
    13801 acgaaaataa agactaagag tctaaataca cctaatccac tcagacagct gagtggattt
    13861 ttcgtatatc ataataaaag tgtcttaaca aaattattaa aatcaaaaaa cgtataatat
    13921 cagatattct aaaaccttga tactgtacgt tttatcatag aaatttttac tttattttct
    13981 catcaaatga gatttgcatc aatctcttgt cttacttgcg tttcttcttc gctttcttca
    14041 ttttgttagc catacgtttc atggactgtt tcatggcaaa ttcaccaatt ttacctttca
    14101 aaccgccacc aaacatctgg ctcatatctg gcattcctgc tcctccgaga gctgataagt
    14161 caggcatacc gccttgtccc atcattcctt caagggcaga catatccatt cctcccatat
    14221 ttggcatatt tttaggaagg ttatttggat taatccccat ttgcttcatc attttattca
    14281 tatccccaga cataacaccc tgcatgagct gtttagcctg gttaaagtcc ttgataaatt
    14341 tattgacttc gacgaatgta tttccagaac cagcagcaat acgacggcga cggcttggat
    14401 ttaacaaatc tgggttttca cgttcttcag gtgtcatcga agacacaatg gcacgtttac
    14461 gagcaatctg gcgttcatcc accttcatgt tttgaagtgc tggattgttg gccatacctg
    14521 gaatcatctt gagcaagtct tccatcggcc ccatattttg cacctgatct aattgatcga
    14581 tgaaatcatt aaaatcaaag gtgttttcgc gcatcttctc agccatttca agggcttttt
    14641 gttcatcgta ttcctgagaa gctttctcaa tcaaagtgag catatccccc atgccaagga
    14701 tacggctaga catacggtct gggtggaagg tttcgatatc tgtaattttt tcacctgtac
    14761 cagtgaactt gattggtttt ccagtgatgt gacgaaccga tagagccgca ccaccacgag
    14821 tatcgccatc aatcttggta aggatgaccc cagtcacttc caactgagca ttaaactcac
    14881 gcgcaacatt ggctgcttcc tgaccaatca tggcatcaac gacgaggaga atttcatttg
    14941 gttgagccaa tgctttcaca tcacgaagct cattcatgag gagctcatca atttgcaaac
    15001 gacccgcagt atcaatcaag acatagtcgt tatgattagt ttgggcttgc tccaaacctt
    15061 gacgtacaat ctcaacagct ggtacttctg ttccaagtgc aaagacaggc acatcaatct
    15121 gttgtcccaa ggtcttaagc tggtcaatgg cagctggacg ataaatatcc gccgcaatca
    15181 tcaaaggacg agcattttct tctttcttga gtttgttggc caatttacca gcaaaggttg
    15241 ttttaccagc cccttgtaaa ccaaccatca tgatgatggt tggaatctta ggtgacttga
    15301 taatttctgc cgtatcagaa cctaaaacgg ctgtcagttc ctcatcaacg attttaataa
    15361 tctgttgcgc aggattaagt gtatcaatga cctcatgccc gactgcacgc tcacgaactt
    15421 tcttgataaa gtcctttaca acaggcaaag caacgtcggc ctcaagcaag gccaagcgaa
    15481 tttctttggt tgcctcttgg acatcagact ctgagatttt tcctttttta cggagatttt
    15541 taaagacgtt ctgcaaacgt tctgttaaac tttcaaatgc catgtttctt cctcttattc
    15601 tctattatca atgcttgtta aaatttctat ctgctcctgc agaaaatcat ccttgggata
    15661 gcgctccaag atttggtcaa aaatctgact acggacaatg tagtccgagt acatgtgcaa
    15721 tttcatctca taatcttcca gaatcttttc tgttcgcttg atattgtcat agacagcctg
    15781 acgactaaca ccaaactcct cagctatctc agcaagactg taatcatcag cgtagtaaag
    15841 ctctatataa ttcatttgct tatctgtcaa aagcgccgca taaaattcaa agagcgcatt
    15901 catacgattg gttttttcga tttccataac ttttattata ccaaaaaata gcctaatcta
    15961 ccacactagg gagccaatcc ttgaagatag aaagtagatt tgagaaaaac gagatcctag
    16021 ccccaagtaa tttccaattg atagctggca aagggatgcc cctcttgatt ttgtagttga
    16081 taagctagct caatcttttg cccatctact tgataacggc tcgtttgaat gataaattcc
    16141 tgcatgccca taggggtagg aatataggcc aaactatcac tatcctttaa aaagcgcata
    16201 atggtcttgg gattggaaaa tcggctcatc accagttctt gaccatgaaa tttaataact
    16261 actttttcct tttcctcatt atagaaaagc aggtagctat aatctccttt ttcatgcact
    16321 tccacatcat aaagctggtc aatcacttcc aactgctcat caaactgaat tgtatttcgc
    16381 atccgaatct tcacatcagg tcctctttct tgtctcttgt cctactattt taccaaaaag
    16441 agcaggattt tgctataatg gtcatatgaa cgaaaaagta ttccgtgacc cagttcacaa
    16501 ctacatccat gtcaataatc aaatcatcta tgacttgatt aatacaaaag aatttcagcg
    16561 tttgcgccgg atcaaacaac tgggaacttc cagttatacc ttccacggtg gagaacacag
    16621 tcgcttctct cactgtctag gagtctatga aattgcacga cgcatcacag agattttcga
    16681 agaaaaatat cctgaggaat ggaatcctgc cgagtctctc ttgaccatga ccgctgctct
    16741 cctacacgac cttgggcatg gtgcctactc ccatactttt gaaaatctct ttgatacaga
    16801 ccatgaagcc attactcagg agattattca aaatcctgag acagagattc accaagtcct
    16861 gctacaagta gcgcccgatt ttccagagaa agttgccagt gtcatagacc atacctatcc
    16921 taacaagcag gtcgtacaac tcatttctag tcagattgac gcagatcgca tggactatct
    16981 cttgcgcgac tcctatttta caggagcatc ctatggggaa tttgacctga ctcgcatcct
    17041 ccgagtcatt cgtcctgtcg aaaatggtat cgcctttcag cgcaatggca tgcacgccat
    17101 cgaagactac gtcctcagtc gctaccagat gtacatgcag gtttatttcc acccagcaac
    17161 acgcgccatg gaagttctcc tacagaatct tctcaagcgc gccaaggaac tctatcctga
    17221 ggacaaggat ttctttgccc gaacttctcc acacctcctg cctttcttcg aaaaaaatgt
    17281 gaccttgact gactatctgg ctctggatga tggcgtgatg aatacctact tccagctttg
    17341 gatgaccagt cctgacaaga ttcttgcaga tttatcgcat cgctttgtca accgcaaggt
    17401 ctttaaatcc attacctttt cacaagagga ccaagatcaa cttactagca tgagaaaatt
    17461 ggttgaggat atcggctttg atcccgacta ctacactgcc attcataaga actttgacct
    17521 cccttatgat atctatcgtc ccgaatctga aaacccacgg acacagattg agattttaca
    17581 aaaaaatgga gaactggccg aactctctag cctgtctctt atcgtccaat cccttgctgg
    17641 cagtcgccac ggagataatc gtttctattt ccctaaagaa atgttagacc aaaacagcat
    17701 cttcgcaagc attacccagc aatttttaca cttgattgag aacgatcatt ttaccccaaa
    17761 taaaaactag aagaggaatt ttatgagtat taaactaatt gccgtcgata ttgacggaac
    17821 cctagtcaac agccaaaagg aaatcactcc tgaagtcttt tctgccatcc aagatgccaa
    17881 agaagctggt gtcaaagtcg tgattgcaac tggccgcccc atcgcaggtg ttgccaaact
    17941 tctggacgac ttgcagttga gagaccaagg tgactatgtg gtgaccttca atggtgccct
    18001 tgtccaagaa actgctactg gccatgagat tatcagcgaa tccttgacct atgaggatta
    18061 tctggatatg gaattcctca gtcgcaagct cggtgtccac atgcatgcca ttaccaagga
    18121 cggtatctat actgcaaatc gcaatatcgg aaaatacact gtacacgaat caaccctcgt
    18181 cagcatgcct atcttctacc gtacccctga agaaatggct ggcaaagaaa ttgttaaatg
    18241 tatgtttatc gatgaaccag aaattctcga tgctgcgatt gaaaaaattc cagcagaatt
    18301 ttacgagcgc tactccatca acaaatctgc tcctttctac ctcgaactcc ttaaaaagaa
    18361 tgtagacaag ggttcagcca ttactcactt ggctgaaaaa ctcggattga ccaaagatga
    18421 aaccatggca atcggtgatg aagaaaatga ccgtgccatg ctggaagtcg ttggaaaccc
    18481 cgttgtcatg gaaaatggaa atccagaaat caaaaaaatc gccaaataca tcaccaaaac
    18541 aaatgacgaa tccggcgttg cccatgccat ccgaacatgg gtactgtaaa agtatcattt
    18601 ttcaataaga attgattagc aataaaatcc aatgaatttt tttagcaaac tatttaattt
    18661 aaaacaaaat aatcataata gagacacaaa ttctgattgt aacaattttt acctaaacga
    18721 attagaatgt ggccttactc ctgggcaact catactcata gattggactc aaaaaacagg
    18781 gagaaattat aatttcccaa gatattttaa atactctctt caaattgacc ctgaatctac
    18841 acacaatcaa ttatacaaat taggatactt cactaaaaat aagactttat catatcttac
    18901 agtagtagaa ttaaaaacta tattatctaa acataattta gctacttctg gaaaaaaagc
    18961 agaattaatt acaagaataa ttaataatgt taacattgac aatttagata ttccgttcga
    19021 atttaaacta acaaaagaag cacaaaatct tattatcgaa catagtgact atatcaaagc
    19081 atactatgat aaagacataa ctatggaaga ttattgtaaa gaaaaaaaca atatctcttt
    19141 taaagcaact tttggtgata taaaatggag tctcttaaat aaacaagctc ataggaatac
    19201 tgtatcagga gattttggat gcttatctaa cacacgaaag gctcagggaa gacatttgga
    19261 acaagaaggt aatattaaac atgctttaat atattacata gaatctttga taattactat
    19321 ttcaggatta gaaaacaatt tttcagccac tgattatcca gtatattatc ccgattcgat
    19381 acctgactac tcactaaaac atattcaaac attaatggaa tcattatctg atgacgatta
    19441 tgattttgct tttgatgaag cattatttcg cttctcaatt ttgaatgcaa atcatttttt
    19501 atctaaggaa gatattgact atttaagagt taatttacct cgttccactg ctgaagaaat
    19561 aaacaattac ttaaagaaat atgaatgtta tagtccttta aataatttag aacttgacga
    19621 ttttgaataa attgactata caaacattta tatactcgat atagtctcaa ttttatctga
    19681 tgattgccca aatttttcaa taataaaacg cataatatta tggagacaat cccctatatt
    19741 atgcgttctt ttaatatcaa agactttttg acaaacttct ttgatatcta attacatgcc
    19801 ccctgcagga atcgaacctg caactactcc ttaggaggga gttgttatat ccattgaact
    19861 aagggagcta gataaaaact ctgctgaaaa gcagagtttt ttagtcgaat taacgacgga
    19921 tttctttgat acgagctgct ttaccttgaa gagcacgcaa gtagtacaat ttcgcacgac
    19981 gtactttacc gtaacgaaca acttcgattt tttcaacacg tggagtgtgg attgggaaga
    20041 tacgctcaac acctacaccg ttagagattt tacgaactgt gtagttttct gagattccag
    20101 cacctttacg tgcgataaca acaccttcaa aaatctggat acgttcacgg ttaccttcga
    20161 caactttcgc gtgtacacga acagtgtcac caggacggaa tgatgggata tctgtacgaa
    20221 gttgaccttc agtcaagctt tggattaatg gattcatttt attctcctat ctttgtcaat
    20281 cttgaggaaa cttcctcagc ggataaactg tattcttgtg cgtccattac acacaagata
    20341 cagtttacca aattttcaca aaaaagtaaa gaaatttata gcaaaattcc taaaaaaatc
    20401 gcaaccaaac cacctatgta agtcaaagtc aggtaagaat aaaagacctt cttatcactt
    20461 agcagtcttt gaagttcgtc attcaaggtc gaaaaagttg ttaaaccgcc acaaaatcct
    20521 gttgctagaa tagcatatac ttccttagac tctacatgat tgtagaatac tccaattaaa
    20581 aaacaaccta aaagattagc tatgagcgtt ccgagtggca atttagaagc ttgattatag
    20641 cgagaaaaga aataccgtac gagtgctccg aaaccacaag caattgcaag atagacaatt
    20701 accatttctt cctccctaga aaataagcta agagtaggcc tccaccgatg ctcaaaagca
    20761 aatacaggac taaactaaaa taacgccctg tatcaagcag cttcacagta tcaagcatta
    20821 ggctggaaaa agttgttaaa cctccgcaaa aacccgtccc cagtgctaaa atcaagccct
    20881 tactagtccc cttatagacc agatagccct tgacaacaaa aatcaagcag aaaattccca
    20941 gatagttgac aaagagagtg ccccaaggaa agtctggact ggctggtaac caggtggaaa
    21001 ctagatatcg gacaagtccg cccaacatag cagctagaaa aattcctagc ggataaaatt
    21061 gttctttttt catttgatat tttgatcctg ataatcacgc gaacgtttga gtatgtccga
    21121 aaaagtcgct acaatagtct cctgatagcg cttgtcctct acacgactcc taaccttttc
    21181 aaaaataact tcttctctct tagtatctaa aatcggttta cctgaagctt tcttataagc
    21241 aaccaccccc tcaactaaat gcattcgttc ttctaacagt ttgacaattt ggtcatcgat
    21301 ttgatcgatt tcttgacgaa taatatctaa atccatacag tctcctcctt tatttgaatt
    21361 attgtatcaa aaagccatca attaggctag taaaatccca actctcgata agaaaaatgc
    21421 actgattgat tacatcagcg cacttttatg cttatactac tttagcaacc aattcttctg
    21481 cgaattgttc caagcgttca atatcttctt cctcggcaga aagatcaact ttgacacact
    21541 cagaaccttt ttctgctcct gttgacacaa agatacggtc aaagtcatca acagccttac
    21601 agaattcatc gtagaaggta tctcctgagc cgaccactcc gtagattttg ccattcaagt
    21661 tgagatctgc taggtcttcg tagaagtcca tcatctcatc tggcaattca ccatcaccat
    21721 aagtataggt cgcaacgata gcgatgtctg cttccaagaa gtctgaagcg tcaacagttg
    21781 tacattcatc aacatcaaca tccaagccca agtcacgtaa tttgtctgct acaatatctg
    21841 caatttcttc ggtattaccg gtcatactgg caaatacaat ttttgctaat gccatatcgt
    21901 cctcctcaat ttatctttct ccattatatc acatcttttt cattttaaaa ataaaaattc
    21961 ttgtgctaca atgaaatgag aaagaattga ggttatttat ggagatttgc caacaaattt
    22021 tagaaaaaat taaagaatac gacaccatta tcattcatcg tcatatgaaa ccagaccctg
    22081 atgccttggg aagtcaggtg ggattgaaag ccttgctgga acatcatttc ccagaaaaaa
    22141 ccatcaaagc cgtcggtttt gatgaaccaa ctcttacttg gatggctgag atggatcttg
    22201 ttgaagatag agcctaccaa ggcgcacttg tcatcgtctg tgatacagct aatactgctc
    22261 gtatcgatga taagcgctat agtcaaggtg attttctcat taagattgac caccatccaa
    22321 atgatgatgt atacggtgac ctgtcttggg tcgatactag ttcaagtagc gctagcgaga
    22381 tgattaccct atttgcccaa acaacccaac tagccttggc agatcgcgat gctgagttgc
    22441 tctttgcagg aattgtcggt gatacaggtc gcttcctcta cccttctacc actgcacgga
    22501 ctcttcgcct ggctgcttat ttgagagaac ataactttga ctttgcggct ctcactcgca
    22561 aaatggacac tatgagctac aaaattgcta aactgcaagg ctacatctac gaccatctgg
    22621 aagtggatga aaatggtgct gctcgcgtta tcctgagtca agaagtcttg aaacaataca
    22681 atgtaaccga tgctgaaact gcagccattg tcggtgcacc tggacgcatt gacagagtga
    22741 gtctctgggg aatttttgtc gaacaggctg atggccacta ccgagttcgc ttacgcagta
    22801 aaatccatcc tatcaatgaa atcgccaagg agcatgatgg tggaggccac cctctagcaa
    22861 gtggtgctaa ttcctatagc ctagaagaaa acgaaatcat ctaccaaaag ttaaaaaact
    22921 tgcttaaaaa ctgataaaat acttgccaaa cttttcagaa tctgatagac tagtatggta
    22981 acaatctatg gctcgcaaag agaccatggc agaaaggaaa tattgcaaaa tgaaaaaaga
    23041 tatccatcca gaatatcgcc cagttgtctt catggacaca actactggtt accaattcct
    23101 tagcggttca acaaaacgct ctaacgaaac agttgagttc gaaggcgaaa cttacccatt
    23161 gatccgtgtg gaaatttcat cagactcaca cccattctac actggacgtc aaaagttcac
    23221 tcaagcagat ggacgcgtgg atcgtttcaa caaaaaatac ggtctcaaat aatgataaaa
    23281 gaacagtttc ggctgttctt ttttgtttct tgaaatcaac tgctgttttc atgttccaga
    23341 ctcatctgta ggttcggttt ccatgctact aggcaggaag gaaatagctg tttcaacacg
    23401 tccataatga gctgtactat tgtcacgaac cacactttca ttgatggtcc aagtggaatt
    23461 cattttctta aaagcttctc ggactttttc caaatctttg gaggcaatgg cctgctctaa
    23521 ggtttcaaaa cgaggactta gacggtttac caatttttcc ttttccgcat ctaggtcaac
    23581 aggattttgt tctttttcaa aagctaatag agctgaggaa atttcggtga gtttggcttc
    23641 agtaatatct ccagatagag ctaacttttc cttaacaatc ttaccaacct cagaatcctt
    23701 attttctact ctttcgaagt ctgatgccat cttcgtaacg agtttctggg tctcagtctg
    23761 accaccattt ttaaccgctt tggatgcatc tgtgattttc acaaagaaaa aactcaagct
    23821 ttcttgggca cctgctgggg aaagaattaa aaatgacaaa gctaaaacta gtaaccagct
    23881 tttagccttc caataatttc tgaccaatgt agcctccttt ctccacacca ccaaagcaag
    23941 taaaaagtcc actacctatg tgagtgatgt attcattcat cttatcagta gcacctaggt
    24001 tagtttgaac cttaacaaag ttatcaggat ccttctggaa agaaatgaag agcaatcccg
    24061 tatcaaactg accagtcttt tcatcaatgc catctgagta agagtaagaa caacgcaaaa
    24121 gtggcttgtc cacttactta gccaaacgaa catgcgaatc atctagcaaa aaactcaaat
    24181 tcacttcatc aaactcattt ttttaccgaa aggggcacta ctttccttgt aacgaccaaa
    24241 ggtattttct tgttcttcga gaccagtgcg gtcccaggtc tctaaaaaca tctgaatccg
    24301 acgaactgcc atataagaac cattttccat ccagtcctta ctatcagccc agataacgcg
    24361 gtcaaagtct tgctccttgg ttgaatttgc tgttccatcc ttaaaaccaa agaggttcca
    24421 cggagtctcc attcgtcccc gatagctgca aatccagact gactccaacg aaggggcacc
    24481 gcatttctcc ccttacgtat gagattgcga ataacgtgaa aggcaatttg ctcatcatct
    24541 gcacaagcat gaatcacaat atctccacca gtatattttt cacgtaattg ctccttagga
    24601 aatagaggta aatccctgaa cagtcgaggg cgcttgtttt ccaagttcat ctttttcaag
    24661 aaacttgcag atacaccaaa agtcagcgtc aaacgatgag gattgagccc aactgtctca
    24721 ccagtatcgc tcggaggaaa gagagcattc tgtccatctt ttttaaccaa ttccccctcg
    24781 accaacttgg cactataatc cgtccaatcc ttgaatagct ggataatttt atctctatcc
    24841 gtcgtatgca ggtccaagac aacaaaatag atattctttt gcatgggcgt actatttggt
    24901 acatcaagcg aaccttacga aaacgtctac tatatttaaa ccgctttctt gtcttcttga
    24961 attgagattt tatttttaga cgcgacaatg gtttgagcgt ctgctttctt aggatgttct
    25021 ggacgtggca taatatttcg cca
//
LOCUS       DBERXF010000035        24496 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.35, whole genome shotgun sequence.
ACCESSION   DBERXF010000035 DBERXF010000000
VERSION     DBERXF010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 24496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24496
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.35"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(139..279)
                     /locus_tag="ACL8JK_001547"
     CDS             complement(139..279)
                     /locus_tag="ACL8JK_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786405.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(276..458)
                     /locus_tag="ACL8JK_001548"
     CDS             complement(276..458)
                     /locus_tag="ACL8JK_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786406.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(460..1239)
                     /locus_tag="ACL8JK_001549"
     CDS             complement(460..1239)
                     /locus_tag="ACL8JK_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786407.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKMLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            complement(1518..1868)
                     /gene="rbfA"
                     /locus_tag="ACL8JK_001550"
     CDS             complement(1518..1868)
                     /gene="rbfA"
                     /locus_tag="ACL8JK_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGS1786408.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(2119..4911)
                     /gene="infB"
                     /locus_tag="ACL8JK_001551"
     CDS             complement(2119..4911)
                     /gene="infB"
                     /locus_tag="ACL8JK_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGS1786409.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKTEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            complement(4928..5227)
                     /locus_tag="ACL8JK_001552"
     CDS             complement(4928..5227)
                     /locus_tag="ACL8JK_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGS1786410.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLAKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(5220..5513)
                     /locus_tag="ACL8JK_001553"
     CDS             complement(5220..5513)
                     /locus_tag="ACL8JK_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGS1786411.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(5535..6671)
                     /gene="nusA"
                     /locus_tag="ACL8JK_001554"
     CDS             complement(5535..6671)
                     /gene="nusA"
                     /locus_tag="ACL8JK_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGS1786412.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(6715..7194)
                     /gene="rimP"
                     /locus_tag="ACL8JK_001555"
     CDS             complement(6715..7194)
                     /gene="rimP"
                     /locus_tag="ACL8JK_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGS1786413.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVRIPYSLVSKARLAVKL"
     gene            complement(7320..7955)
                     /gene="trmB"
                     /locus_tag="ACL8JK_001556"
     CDS             complement(7320..7955)
                     /gene="trmB"
                     /locus_tag="ACL8JK_001556"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGS1786414.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(7952..8746)
                     /gene="ccrZ"
                     /locus_tag="ACL8JK_001557"
     CDS             complement(7952..8746)
                     /gene="ccrZ"
                     /locus_tag="ACL8JK_001557"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HGS1786415.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(8907..9518)
                     /locus_tag="ACL8JK_001558"
     CDS             complement(8907..9518)
                     /locus_tag="ACL8JK_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS1786416.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            complement(9669..9902)
                     /gene="blpZ"
                     /locus_tag="ACL8JK_001559"
     CDS             complement(9669..9902)
                     /gene="blpZ"
                     /locus_tag="ACL8JK_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpZ"
                     /protein_id="HGS1786417.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(9944..10633)
                     /locus_tag="ACL8JK_001560"
     CDS             complement(9944..10633)
                     /locus_tag="ACL8JK_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS1786418.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            complement(10685..11068)
                     /locus_tag="ACL8JK_001561"
     CDS             complement(10685..11068)
                     /locus_tag="ACL8JK_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGS1786419.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            complement(11697..12016)
                     /locus_tag="ACL8JK_001562"
                     /pseudo
     CDS             complement(11697..12016)
                     /locus_tag="ACL8JK_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826248.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
     gene            complement(12536..12655)
                     /locus_tag="ACL8JK_001563"
     CDS             complement(12536..12655)
                     /locus_tag="ACL8JK_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGS1786420.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(12759..12908)
                     /gene="blpO"
                     /locus_tag="ACL8JK_001564"
     CDS             complement(12759..12908)
                     /gene="blpO"
                     /locus_tag="ACL8JK_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HGS1786421.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(13152..13400)
                     /gene="blpK"
                     /locus_tag="ACL8JK_001565"
     CDS             complement(13152..13400)
                     /gene="blpK"
                     /locus_tag="ACL8JK_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpK"
                     /protein_id="HGS1786422.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAVVAAL
                     GCAAGGVKYGKILGPWGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(13469..13738)
                     /gene="blpJ"
                     /locus_tag="ACL8JK_001566"
     CDS             complement(13469..13738)
                     /gene="blpJ"
                     /locus_tag="ACL8JK_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HGS1786423.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(14205..14402)
                     /gene="blpI"
                     /locus_tag="ACL8JK_001567"
     CDS             complement(14205..14402)
                     /gene="blpI"
                     /locus_tag="ACL8JK_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HGS1786424.1"
                     /translation="MNTKMMEQFEIMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            14683..15270
                     /locus_tag="ACL8JK_001568"
     CDS             14683..15270
                     /locus_tag="ACL8JK_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGS1786425.1"
                     /translation="MTSYKRTFVPQIDARDCSVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLAPKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLISHYYQYRWFLLSPRNLR"
     gene            15197..16840
                     /locus_tag="ACL8JK_001569"
     CDS             15197..16840
                     /locus_tag="ACL8JK_001569"
                     /inference="COORDINATES: protein motif:HMM:TIGR01193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HGS1786426.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLLSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            16851..18212
                     /locus_tag="ACL8JK_001570"
     CDS             16851..18212
                     /locus_tag="ACL8JK_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HGS1786427.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            18269..18397
                     /gene="blpC"
                     /locus_tag="ACL8JK_001571"
     CDS             18269..18397
                     /gene="blpC"
                     /locus_tag="ACL8JK_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HGS1786428.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(18468..19808)
                     /locus_tag="ACL8JK_001572"
     CDS             complement(18468..19808)
                     /locus_tag="ACL8JK_001572"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS1786429.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLLKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(19822..20559)
                     /locus_tag="ACL8JK_001573"
     CDS             complement(19822..20559)
                     /locus_tag="ACL8JK_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1786430.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALNYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(20573..20902)
                     /locus_tag="ACL8JK_001574"
     CDS             complement(20573..20902)
                     /locus_tag="ACL8JK_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS1786431.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLK"
     gene            21179..21508
                     /locus_tag="ACL8JK_001575"
     CDS             21179..21508
                     /locus_tag="ACL8JK_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGS1786432.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(21676..22725)
                     /locus_tag="ACL8JK_001576"
     CDS             complement(21676..22725)
                     /locus_tag="ACL8JK_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1786433.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWIFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFCQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(22722..23453)
                     /locus_tag="ACL8JK_001577"
     CDS             complement(22722..23453)
                     /locus_tag="ACL8JK_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1786434.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTMQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            23521..23931
                     /locus_tag="ACL8JK_001578"
     CDS             23521..23931
                     /locus_tag="ACL8JK_001578"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGS1786435.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            23941..24228
                     /locus_tag="ACL8JK_001579"
     CDS             23941..24228
                     /locus_tag="ACL8JK_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786436.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
BASE COUNT         7719 a         5331 c         4150 g         7296 t
ORIGIN      
        1 gcaaggtgaa gctgacgtgg tttgaagaga ttttcgaaga gtataaaatg attttactgc
       61 ttatattata ccatatggag agagattaaa aaactagcag tggagttcct gctagttttc
      121 tgcgacttgg attaccatct agataagttt aaagaaccaa tccaatatct tgtaaaacag
      181 caattgaact gcaaaagaaa tgatcatcca aaagaatttc acaatcccaa taatcggttt
      241 gataaaaata atggcaagaa gtccccagaa aaatttcatt ctctctcctc tggcttaatg
      301 agccaccgag ccgtatccat taacttgtcg gcaataaaaa gtttccccag accgacaacg
      361 gcattatcat ctttctttat cgttttcatt acttttacac cttgcacggt caaaaagtaa
      421 ttaccataaa ttttagctag agtttttatg agtcccatat tactctcctt cgatgatttc
      481 agcctctttt cggattgttt caacatcttc ttgatattga acttcactat agttaactag
      541 cttggacaat tctttctgca agctttcacc catcggtttc atagttgcaa aggttaaacc
      601 acctgaaatg ataccaccca agataggaat aaatttcccc attcctttgg ccagccctcc
      661 cttggtaaga ttcacaccaa atattcttaa gacttttttc aaaataggat accaaagcat
      721 ctttgttaaa gctttattag gtactgtttt cattacctgt ttggcaattg ttataccacc
      781 agcacgtagc aaagcagcag ttccattcac ccccaacatg acgcctagat aaagcaaaag
      841 ggtattttga gcatcttcac tcaactcatc gcgtgaagcc caaagatcct cataaccata
      901 aatataacct aattcttggg ccaatttcag agagaaacca taaaattgag ccacatcagc
      961 tggaatggta attgccatag caagccctcc aggtaatcct gccaaaacag aagtcccact
     1021 cgctaataaa acattatccc taatacaggc attagccact cgatctaaga tttcttgaga
     1081 taagagagac gttggacctt gttccaataa ggtaggaatg tcctgtggac ccaattcttt
     1141 ggaaaactta tccactaaaa atttcgaacg atcaacctta acaactggta gttttaccac
     1201 ttgttgtaat acttgcatag ctaagtcttg ttcagccata tacaaactcc ttatttcttt
     1261 tttacacctt atcatattat atttcctaca aaaaaagcat tttctaatta gataacatta
     1321 aaaaatacag aacccctttt ttatagtaaa atgaaacaag aacaggacaa atcgatcagg
     1381 acagtcaaat cgatttctaa caatgtttta gaagtagagg cgtactattc tagtttcaat
     1441 atattttaaa agaatatttt tccatttcaa attcaaccta ttttcctcca ccaaaaaaga
     1501 ggggcaaccc ctcttcttta gttcttatcc agattgcgta gcatctcgtc aatcttgttt
     1561 ccatactcga tggactcgtc tttgacgaag gtcaaatctg ggattttgta caatttcaaa
     1621 ttgcgaccaa gttcacgttt gatggtacca gttgcttttt caagcccgat ttgggctttt
     1681 tggttatccg aagcaaggtt actcaaaatg gtgtaataaa ccttggcaac agacaagtca
     1741 cccaacatct gaacatctgt gatggtcaca ccttggacac gtggatcacg aactttcttt
     1801 tgcaaaatct cattgacttc acgcttgatt tccatgccca cacgatctgt acggaaatga
     1861 tttgccatga tattcctttc tctactttga accaaaagct aggccagcag acctagctat
     1921 tttaaacttc ttgattttca gtttaaattg aaacgaagtt caatttgaag tcatctgctt
     1981 ctttcgccgt ggtgaaagtg atggaactga tttatcagtc ccatcacagg ggatttttga
     2041 gaccctaggc tcaaaaataa gcaatgaaac catcggtttg cttgcgtccc tcaccaccta
     2101 agaaaggagc aaaaaatctt atctcttgat ttcttccatg acatacgcct caatcacatc
     2161 atccatctta atatcattgt agccgtcgat catcaatcca ccttcacggc cgtttgtaac
     2221 ttccttaacg tcatctttat agtgtttcaa gcttgcgagt tcaccatcat agataacgac
     2281 accatcacgg ataacacgga ctttagagtc acgggcaacc ttaccgttga taaccataaa
     2341 tccaccgata gttcccactt tagacacctt gaaggtttca cggataaccg cttcaccaat
     2401 aactttttct tcaaattctg gatcaagcat ccctttcata gcttcttcca tctcttcgat
     2461 aaccttgtag ataatgctgt gaagacggat ttccacatcg tcagcttctg cttgttgacg
     2521 agcttgtggt gtagggcgta cgttgaaacc aacgataaag gcatttgaag cttcggcaag
     2581 ggtcacgtct gattcgttga tagcaccgac cgctgagtgg acgatagtca ctttgacacc
     2641 ttccacgtca atcttttgaa gtgaggcaga aagggcttca acagaacctt gtacatcagc
     2701 cttgatgata acattaacag atttgagttc cccagcttta agggtatcaa agaggttttc
     2761 aaggctaaca cgttgggtag cttgacgttg tttcatgagg gcacgtttgg cacgctcttc
     2821 acctgctgca cgcgcagatt tttcatcctc gtaaacggca aagtggtcac ccgccatcgg
     2881 tgcttcgttc aaacctgtga tagagactgg tgttgatggt ccagcaactt taacacgacg
     2941 accaaggtcg ttggtcatag cacggacacg accgaaggta tttccgacaa cgattgggtc
     3001 ttgaacattc aaggtacctt gttgtacaag aagggttgcg accgcacctt ttcctttatc
     3061 caagcgcgct tcgataaccg taccgattgc acgcactgtt gggtctgcct tgagttcttg
     3121 gatttcagct acaagaagga ctgtttccaa caattcttcg atattttggt tgaatttagc
     3181 tgagatttca acaaattcag aatctccacc ccaagcggtt gacatcacac catgctctgc
     3241 caattcaccg ataacgcgtt ctgggttagc acctggttta tcaatcttgt taatggctac
     3301 gatgattgga acgttagctg cttttgagtg gttgatggct tcaatagtct gaggcataac
     3361 cccgtcatct gccgctacga ccaagatcgt aatatcggta acagaagcac cacgcgcacg
     3421 cattgatgta aaggccgcgt gtcctggtgt atcaaggaag gtaatcttct taccattttc
     3481 cacgatttgg taggcaccga tatgctgagt aataccacct gcttcacctg tcgcaacacg
     3541 tgagttacga agagtatcca aaagggttgt tttaccgtgg tcaacatgtc ccatgatagt
     3601 aacaactggt ggacgctcaa ccaattcatc ttcattgaga taaccatctt cgacaaagaa
     3661 acgttcgatg tcagcattat ccacttcaac cttttgtttg gcttcgatac cgtaatccac
     3721 catgaggagt tcaattgttt ccccatctaa ggattggttt tgtgtggcca tgacacccat
     3781 catgaaaagt ttcttaacga tttcagctgg ttcacgtttg atacgttttg cgatttccgc
     3841 aacggtcata ccatctgtat attcaaattc tgttggcaat tcatggaatt tacgctccgt
     3901 aacaggtttt ggagtctgat tacggttgtt cttgttattg ccttttttgt tctttttgtt
     3961 gttattccag ttactattct tttgatttct cacttgattt tgactacttc gattcttttg
     4021 ttgttttcta ggaccatctt cttcatgatc ataatcgtca cgatttttgt ctggtcgagc
     4081 ttgtttttta cgacgtgtat ccactgcagg ttcttttttc tcagggacga cttcaaccac
     4141 tgcttgaact tgctgtgctt gttcagctaa cttagccgct tcttcaaaga tttcctctgg
     4201 ttccttgcgt ttgttagctt gagccaaggc ttctttagca gcctgatact gcttgaagcg
     4261 ttcctcactt gaacgagcgt actctgcatt ttgctctgct tttagggctg ctgcacgggc
     4321 tttaaagtca atacgtggag ccgcttgatt tgaacgtttg tcctcttgct gacggcgctc
     4381 atttctacgt ttttgctgac cttgctgctt cttagcttgg tcattaaagc gacgattgtc
     4441 gcggttgctt tgaccttgtt ttccaccatt acggccatcg tttttctgac ggtttccgtt
     4501 ttgttgttgg tcacggttat tgcccttatt ttgcttgcgt cgttctgcct gctctttagc
     4561 acgggcttca cgctcagcct tgaaattacg gctttgcggt ttcgctgcta ctttttctgt
     4621 tttcggagca actggctcag ccggttttgc ctcttcctta gctacagctg gtttagctgg
     4681 ctcagatttt tcggttttct tttctgcact tacttttggt gctgcaggtt ttgcttctac
     4741 tttcggagca gctgcaggct taaagctggc agcaattttt gcagcgacag cttcttccac
     4801 acttgatgag tggcttttca catccaagcc caactctttt gcacgcgcta caacttcttt
     4861 actttctttt ccaagttctt ttgcgatttc gtacaatctt ttcttagaca aatcatgtcc
     4921 tcctcttcta ttccataaga gacctcattt tctttgtaaa tccagcatct gttacagcca
     4981 aaacctttct cgatttcccg actgctatgc ttaattccag tgttgaaaac acggttacaa
     5041 tttctacttg ataataatga cttttatctt gaatcttctt ggccagattg ggtccagcat
     5101 catgagctag aaagaccaac ttggccttgc cgtcttgaat ggccttgacc accaattctt
     5161 cacccgatat gatgcgccct gctcgctgag caagccccaa gagattactt atcttttgct
     5221 tattcaagtc ccaactctct tcttttcact ttgtgatcca cataagcgat caactcgtca
     5281 taaaagcttt cttccacttc catgctaaag ctgcggttaa agaccttctt ctttttcgcc
     5341 tctagggctt ctgcattgtc tagtttgata taagcgccgc ggccattggc cttgcccgta
     5401 ggatcaataa agacttgtcc ttccttgttc ttgacaatgc ggagcaaatc acgcttatca
     5461 atcacttcgt tagacacaac agacttgcgc aaagggattt ttcttgtttt catctttccc
     5521 tcctctagca gcttttattc ttctacagta tcgttttcta cttccaactc tactgaagca
     5581 gcgtcttcca tggcttcaaa ttcgctagca gacttgatat cgatacggta accagtcaag
     5641 tgagccgcca agcgcacgtt ttgtccacga cgaccaatgg caagagaaag cttgttatct
     5701 ggaacaacca ccaaggcacg tttgctgtcg ttttcatcaa agataacttg gtcaacctca
     5761 gcaggagcga tggcattgta gataaattca gctggatctg ctacccactc gataacatcg
     5821 atattttctt cgattggtac catgcggtca tttttagcat cgtaacgagc tgggtggaat
     5881 ttgctagtaa tcttcttgat attagcacca ccacgtccaa cgattgtacc gatagcatcc
     5941 acgtttggat tgtggctacg aacagcaacc ttcgtacggt cacctgcttc acgagccacg
     6001 ctcatgattt caacagttcc atcataaact tctggaattt cttgctccat caaacgtttg
     6061 atcatttctg gatggctacg gctaacaaag acgttcacac cacgagggtt gtcttcaacc
     6121 ttgtaaacat aaacttcgat acgatcatga gaagcaaaaa cttctccagg aatttggtct
     6181 tgttttgaca attgggcttc gatgctacca aggttgacat agataaagcg gttgtcaaag
     6241 cgttctactg taccagacat gatttcttgc tcatgttctt tgtaagtatt gtaagtgatg
     6301 gcacgtgttt gcttgcgcat tttttccatg atggtttgtt tggcagattg ggctgctaca
     6361 cgaccaaact cagctggtgc ttcttcaaac ttgattttgt ctccaagttc ataagctgaa
     6421 ttaatggcaa gagcatcttt caagctgatt tccaaacggc tatcaaatac ttcatcaaca
     6481 acttcacgga cagtataaac tgtaaagtca cctgtttttt cgttgaagtc aatagctacg
     6541 ctgtctgact gaccatagcg tctgcgataa gcggaacgaa gcgactctac tactgcgtcg
     6601 atgatatctt cttttttgat tcccttgtct tcttccaaaa tgcggaaggc ctctagcatt
     6661 tctttactca tgttttcttc acttttgaat cctcaaaagc tatcctttct ttttctataa
     6721 tttaactgct aaacgtgctt ttgatactaa actgtatgga attcggacgg ttttcttacg
     6781 cgtcttgtcc atatattcca tagtcaactc gtcctcttcg aaggccaaca aagttccttc
     6841 aaagaccttt tgcttatcga tggcttggta gagtccgaca tggatgtatt ttccaaccgc
     6901 tccagcgacg gcatccttgg ttttcaaagg acgttccaag cctggactgg taatttctag
     6961 gaaatattgt tctgggaagg gatctggctt gatggtgtct aggacaggac tgataatttc
     7021 tgtcaagtct gccgtgtcgt tcaaggtaat tccttcgggt ttatctacaa aaatactgag
     7081 aatcatgtca ctgccaatct ttccatactc gatatccacg agttcaaaag gagcttctat
     7141 gacaggttct acaacttctc tgactaattc tacgattgtt gcgattgcgt ccacctcctc
     7201 ataagcaaga ggcgaagata tttccccgcc tcacttttca tattcttact atcagtatag
     7261 cacgtttgcc aacttatgta aagcaaaagc acttgtacag cctaatttta ggctatctct
     7321 taaaattctg cctcaactcg gtagataact tgccccttgt ttgagaattt ttgctcgtat
     7381 tctgtcatga cattgccttc aaaatcactg gcatgcaaat ctagccagac accattgagt
     7441 ttcatgccat attgagaaaa gctcactaaa ctgtactcaa acaagccacg gttatccgtc
     7501 ttgaaatgaa tttctccatt ttcaggcaag atacgtttga aggtgtccaa aaaggtcttg
     7561 taggtcaaac gacgcttttc atggcgtttt ttcggccatg gatctgaaaa gttcagatac
     7621 aagcgatcaa tctcaccgtc ttcaaagtag tcagttaagt cagaaccatc tacccacaag
     7681 agcttgatgt taggcactcc aacttcaagc accttgtcca aagcgtagct caaaacagac
     7741 ttttgaatat caatcccgat atagttgatg tcagggtttt gcttggccat acctgaaaca
     7801 aaggcaccct ttccacttcc aacttccaca tgaatgggat tatcattgcc aaacaagtcc
     7861 cgccattttg ccttggcttc caagggattg aggaccacat actggggatt tgcctctagt
     7921 aattctgttg cccctttacg atttctaact ctcatcttct ctttccatac ttgtctcgga
     7981 aatgacgcaa accatgaatc tcccgattga cattttctaa atcttggttc atataatact
     8041 tggaaatctg actcaaataa gacaattgac cataccaata caatttactt aataccgttt
     8101 gattgtactt gtaaccgtag taggtcaacc attccttcca ctgatgttct gaaatataat
     8161 ggcagagcat atgggccaca tcaaacatgc gatcggtcaa gcgaaccgaa tcccaatcta
     8221 ctaaataaat caagccacta tctgtctcaa tccaattact atgtcgtaca tctccatgga
     8281 caatggtcgc atggtcctct ctaaatcctg gaatagtctg acgtaaatca gccatcactt
     8341 cactgataaa atgattttta cgcaaagcat ctggagccgt ttcctgccaa gactgtagta
     8401 aatctacagg tgtttccatg gcatagccca aacgactcaa ttgtgtcatc aacggacgtg
     8461 agcgatgaag acgggttaaa atattgacga tttgcttacg attcatatca tagggggtca
     8521 atatcttgcc tgtcaaccat tcttgagcac acatatcacg cccatctgcc aaacgacgac
     8581 tccataataa ttgtggagca atttgttctc tagctagacc aggtaggatt ggagaggtgt
     8641 tcatttttac aaagatgcgc ttcccatcag gatagctacc catataagcc ttgccacttt
     8701 tcccaggtat gggagtcagt gttagctcat tatcacccaa atccatttct ttcctccgta
     8761 taaagtttcc ttactattct actagttttt ggcctattcg tcaaccactc taacccgatt
     8821 ctcaaagaaa agcctctgga ttggcttggg tatcattata gcttgaaaaa ggtaagcacc
     8881 gtcttctgct taccttttca taatttttat aaataatata agagtggcca actgttgtaa
     8941 agcatatgga ctagagtaga aacccatagg ttttgactct ttttataagc aaagcccagc
     9001 aacaaacccc caagtagata aaaaataaac gaagggacat tagaaggtcc atgcatgaaa
     9061 gaaaagagag aggaagttag cacaagccct aaccaagaat tgtcaaaaac cgcaccttga
     9121 agaagtcctc tgaaaatgag ttcctcctgg atggggccaa aaactgaggt agttaaaatc
     9181 aaagacaggg aaattcctct gctgacttcc gccaagtgtt ggacccctga gccagaagaa
     9241 acagcgaaga aatgaatata aaccagcgtc tcaagtacac ttagaagaaa gattgcaatg
     9301 aaaagcaaaa gttgtttctt gcttaacatc ccaaaagaaa tcatttcaaa ctttctagca
     9361 taagcaacac tcagcgaggt tacaagaaga cttacaagaa tcaatgcaga ttcattttga
     9421 aaaaaacccc catggttaat cgtataagga actgtaatga caattattag tactaaaaat
     9481 ccaaaacaca aggcatgaaa tttatcaaaa aactccataa aattatcctc ctcaacaaac
     9541 agacttccta cacgtcattc tttagttcta gcctttccaa aacaaaccat tttatactct
     9601 tcgaaaatca aattcaaacc acgtcaacgt cgccttgccg tactcaagta cagcctgcgg
     9661 ctagtttcct agtttgctct ttgattttca ttgagtatta gtaaccaaaa tccgaccaca
     9721 tagccagccc ctatgaatat agccattaaa gctagcatgg aatttaggaa attaaaaacc
     9781 accgcagata caaaggttag cacaaaaaca ttaaaagcaa tggtgtcaga agccaagact
     9841 agaatatagg gtgtcaaccg atctaaagtt ttggaatcta ggaaaaataa gtgtttatac
     9901 atgatgacct cctctatggc tgaaaagcaa gccttttgtt tttttacccc aagaccctat
     9961 gtagaaaagt gagcaaaaac gggaaggtcg ctacaatatt attgatcaca tgcaccgcat
    10021 aggatggata aatgctcttg gtatagcggg tcaaaccagc aaagatgatt ccaactgttg
    10081 caaagacgaa gatatctaac agactaggca ggcttgaaaa atgagggaga gcaaataaaa
    10141 tagaaggaag aagcaaatca agaccaaatc gcgaatgctt aaagaaagca tgttgcagta
    10201 atcctctata aatcaattct tccatcagtg gaaccagaaa gaacagggct atataaatac
    10261 ctagctctgc aaagttagtc ccactataac cgatcaatac agcccaacct tcagcagttg
    10321 actgaacatg tttagctgtc tgaacgttaa aagagatctg gagcactacc actaatactg
    10381 tcaaaatcga ataccaaagc catttttttc ttggaatgtg aaagagataa ccatgacctg
    10441 tcttaaccag aatccaaatc atgactccgc taaatagcaa actcaagaaa ttttgaatcc
    10501 agacgaaatt gccaatctgg gaagaaaatt gccaataatt ttgaataata agcgtcatct
    10561 gagaaagacc aaatacgaaa aataagtaag agaaaactgc acttattttg aatagaagtt
    10621 gatacttttt catagaaatc ctccctacta tgacctcacc ttgtcaggct ctactgctgt
    10681 aagattaaga agacagtttg ttttttttaa ggctaacctg actactagat aatagataca
    10741 ttaaggcatt aaagacaatg aaaatatgtc catagaataa aatcaacctc gcatccaaac
    10801 caagataaag tttgattatc aaaaagatga gcaaaagaat ttgaaaccat aaggtttttc
    10861 caaaaataaa tttaaagcga tttcgaatat ctacttcctt gatttttacc gccacccctt
    10921 tattagcaag aaggaaaact cctgcttcaa acaaaccact gtaaagaaca agccacccaa
    10981 tagatacgat agagatttgt aaaaatgtcc ctaaaagaat atccaacaca ctactcaaga
    11041 aaataacaaa aaataatctg tatttcatat taaatacctc cattcattta tttcactaac
    11101 aatttaatag agccttctac tcaaatatcc tgtcagaaaa ggatagaaag ctacttttta
    11161 taatacttca agccccacat gagcagaagc gtgataaaca agcagagaat acacctatat
    11221 aagcgattag ttgttgatag aattctgttt ctgaaatacc tctatacaaa caaatgacaa
    11281 acataaaatc tgccaagccg ataaacataa gttgattggt tctaggacta accaaatcat
    11341 catttactta tatttaagag tatctctttt atgttaatgt atgttagcac tgaaaagcaa
    11401 gacaggccaa taatatttaa aatgaacagt aacggggtta agtctctaaa aaaattatct
    11461 actgacacta caagaaatac tatacatatt atagtcgaaa ctatcttttt cttatccata
    11521 attatttact cctttcctaa caaatccaac ttatcaatca agagcgattt ttaacataat
    11581 gtagcagcac ccgttgcaac tttgacaagt ttagtatatc attgtttttt aaaatttttc
    11641 atccaaatct tgaattgtca tcgaaacctc ctaaattgca aaaacttcat tagcccctac
    11701 tttttataat acttcaaacc ccaaatgagt agaagcatga tgatcaagca aagaatagca
    11761 ccaatataag cgattagttg ttgataagat tctcctgctg tgatacctct atacaaacaa
    11821 ataatagaca taaagcctgt caagccgata aacatgagtt gattggttct aggactaacc
    11881 aaatcatcat cttcaaactc tcttaatctc atttccctag taagataaac agtaaccaaa
    11941 atagaagtca agttaataac tactaaaaga aattggaaaa ctgacgaaat agaaatagat
    12001 aagtagaaac aagcaaaggc aactgaccca ggaacaatct cacaaagaat atgattcttt
    12061 ttaatcaaga aaatctttca tttcttttct ttctttttaa ttaaagaaaa atagatcata
    12121 accgcaatca tataggctat ggtataaaat agattatacc aaatactctc cctaagcgga
    12181 taaagaaaga tggacatgat cagatacaga acgaaaataa tcagtatttt tttcttcata
    12241 agttttcctc ctaaatgtgc gatttatctt agttgagcaa gaacatttac actgctagta
    12301 tagcacttat tttgaccttg gatcactcaa atcataaatg gtcatcaaaa cctcttgaat
    12361 tgtaaaaatt aaaaaagcaa gcatgaaaaa catactttcc tctttatatt gtattgatac
    12421 caacttgttt gtagactttt catcctgcta tcacatatca ttttgacagg cgaaacaata
    12481 ttaaagaaac tcccctgtaa attaagctag caaatacagg ggagaaattt attttttaga
    12541 gagtactatc cgtatccttt ttggaagatt ttgaaaatat ttttctaatt aagtcatcca
    12601 tataaggacc aaatatacca actactaaac caataataaa acttttaaaa tccataatta
    12661 ccaccaacat gttgctgcat aggctacacc tccaagtata gctccacctg cagcaccagt
    12721 tacacctatt cctatagcaa atggtcccaa tagaaatgtc aaaccgttgt tgcacaccca
    12781 tcaattgcgc catatgcaac ccctgctgca caactaattt ttcttcccca atcaatatct
    12841 ccaccttcaa cgcaagcaag catttcatta tccataacag aaaattgtga catcattttt
    12901 gtattcatat agtatgtcac ttttcagtta cggaacaagt ttaatataaa aattatcaaa
    12961 aaaacatagg caataaagag aaaaattaat ttatcataga ttagaaataa tatgacaaaa
    13021 caattcaatg atgttaattc aatagtcttt tgttttttat cagagatact tatggataga
    13081 taaataagat aggtttgaaa agcgaagaga ataataaaga atatagcctt cataaaattt
    13141 agctttcatt tttatgatgt agcggtatag gctaaatatc cacaaaccac tgctcctcca
    13201 attcctccta ttgcagcgcc ccatggtcct agaattttcc catatttcac tccacccgct
    13261 gcacaaccta aagcagcaac tacagctgct cctccaacac ctgctttggc aaaatctccc
    13321 caattgcatc cgccaccttc aacgcaagca agcatttcag tatccataac agaaaattgt
    13381 gacatcattt ttgtatccat gacaaatact ccttttttaa aaaactaaaa taaatcagaa
    13441 tagaatcctc ataattttac tataagtctt accaacttag tcccaattta tcaccaacca
    13501 tacctcctaa gcatgttaat ccacccccaa ttgcaccaat gtgtgctcca acaaatgcac
    13561 cagcaagtcc agctactcct aaagtggcca aacctgctcc agttccacca gttataattc
    13621 ccgtagtgac tcctgtaatc agtgcatttt gacaatcagt ggagctatac cccccttcaa
    13681 ctttcgcaag catttcagta tccataacct ctaactgtga caacattttt gtattcatga
    13741 tgaatacctc ctttttattt tcaatttgtt accaaagtct taaattcaat aaacaaatag
    13801 attttttata gtatcttttt gattttctta aaaaagtata tacgtctact atcttcttaa
    13861 aggtagcagt acctattttt tagtctaaga tttcaataat cttgagtatc taaaatatct
    13921 taatttcgtt attctccttg caataaaaag ttttactata ctatttatta acttgcagaa
    13981 agcaaaaaat attagtaaat aatagtttat agttaagttt tttattccta ccaatccatc
    14041 aactaagtaa agcatcaacg attacataaa cgattgataa tataattaaa attttgctaa
    14101 ctatcttatt ctcatcattc ttagataact ttgatatttt gtaagtaagt aaataagaca
    14161 gtaaattaat agcgataata atactatatt taagaatcat aatcttacaa agaggacata
    14221 attcctgaac ctacacaaat aagtgttgct gctcccccag ttatcggacc agtcgcagca
    14281 gctaatagta ctgctccaat acaaccaccg attgcagatc ctaaattgcc tcttcctcca
    14341 ctaactattt cgagttcttc attatccata atctcaaatt gttccatcat ttttgtattc
    14401 atgacaaata ctcctttttc tttttttatt tttgtcttgt tgtaactttg ataagtttag
    14461 tatatcatcg ttttttaaaa tttttcatcc agatcttgaa ttgtcatcga aacgtcttga
    14521 attagctttt ttatttcaag ccacctctaa atgtttaaaa aaaataattt ctaatcactt
    14581 ttttaccatt caggaagttt taatgactat tcaagatttc ataaaatatg aacttagttt
    14641 tatgacataa tagacctatc cactatatga aaagaattgc caatgacttc ttataaacgt
    14701 acatttgttc ctcaaataga tgcgagagac tgtagtgtcg ctgccttagc ctcgattgct
    14761 aaattctatg gttcagattt ttctctagct cacttgagag aacttgcaaa gaccaataaa
    14821 gaagggacga ctgctcttgg cattgtaaaa gccgctgatg aaatgggctt tgaaacaaga
    14881 cctgttcaag cagataaaac gctctttgac atgagtgatg tcccctatcc atttatcgtt
    14941 cacgttaaca aagaaggaaa actccaacat tactatgttg tctatcaaac aaagaaagac
    15001 tatctgatta ttggtgatcc tgacccttct gtaaaaatca ctaaaatgtc aaaagaacgc
    15061 tttttctatg aatggactgg agtagctatt tttctagctc ccaaacccag ctatcaaccc
    15121 cataaagata aaaagaatgg tctactaagc aagcttcctt cctctgattt tcaaacaaaa
    15181 atctctcatt gcttacattg ttctctcaag cttattagtc actattatca atataggtgg
    15241 ttcttactat ctccaaggaa tcttagatga atacatccca aatcagatga aatcaacttt
    15301 aggaatcatc tcagttggtc tggttatcac ctatatcctc caacaagtca tgagcttctc
    15361 cagagattat ctcctaaccg ttctgagcca gagattaagc attgatgtga ttttatccta
    15421 tattcgccat atttttgaac ttcccatgtc tttctttgcg acacgtcgta caggagaaat
    15481 catttcacgg ttcacagatg ctaactctat tatagatgcc ttggcttcta ccattctttc
    15541 tcttttcctg gatgtttcta ttctgattct tgtagggggc gtcttactgg cacaaaaccc
    15601 taatctcttc cttctttctc ttatttctat tcctatatac atgttcatca tcttttcttt
    15661 tatgaagcct ttcgaaaaaa tgaaccatga tgtcatgcaa agtaattcta tggttagctc
    15721 tgccattatc gaagatatca acgggattga aactataaag tcgctcacaa gtgaagaaaa
    15781 tcgctatcaa aatatagaca gcgaatttgt agattatttg gaaaaatcct ttaagctcag
    15841 taaatattct attttacaaa caagtttaaa gcagggaaca aaattagttc tgaatatcct
    15901 tatcctatgg tttggcgctc aattagtcat gtcgagtaaa atttctatcg gtcagctgat
    15961 tacctttaac acacttcttt cttactttac aactcctatg gaaaatatta tcaacctcca
    16021 aaccaaactc caatctgcga aggttgctaa taaccgtttg aacgaagtct atctagtcga
    16081 atctgaattt caagttcaag aaaaccctgt tcattcacat tttttgatgg gcgatattga
    16141 atttgatgac ctttcttata agtatggttt tggacgagat accttaacag atattaatct
    16201 cacgattaaa caaggagata aggttagcct agttggagtt agtggttctg gtaaaacaac
    16261 tttagccaaa atgattgtca atttctttga accctacaaa ggacatattt ccatcaatca
    16321 tcaggatatt aaaaacattg ataaaaaagt cttgcgccgt catattaatt acctaccaca
    16381 acaagcctat atctttaatg gctctatctt ggaaaactta actttgggcg gtaatcatat
    16441 gattagccaa gaagatattc taagagcttg tgaattagct gaaattcgtc aagacattga
    16501 aagaatgcct atgggctatc aaactcagct ctctgatgga gctggtctat caggaggaca
    16561 aaagcaacga atagccctcg ctcgtgctct tttaactaaa tctcctgttt taatactaga
    16621 cgaagctact agcggtcttg atgtcttgac tgagaaaaag gttatagata atcttatgtc
    16681 tctaactgat aaaaccattc tctttgtagc ccatcgtctc agtatagccg aacgaaccaa
    16741 ccgtgtcatt gttcttgacc aggggaaaat cattgaagtt ggtagtcacc aagagttaat
    16801 gcaggcgcaa ggtttctacc atcatctatt caataaataa ggagaatgtc atgaatccta
    16861 atctttttag aagcgtcgag ttttatcaga gacgttacca taactatgcg acagtgttaa
    16921 ttatacctct ttcattacta tttactttca tcttgatttt ctcccttgtt gccacaaaag
    16981 aaattactgt tacttcccaa ggagaaatcg cccctacaag tgtcattgcc tccattcagt
    17041 caaccagtga taatcctatc ctagctaatc atttagtggc aaatcaagta gttgaaaaag
    17101 gggacttact catcaaatac tctgaaacaa tggaagaaag tcagaaaact gccttagcaa
    17161 ctcaattaca aagacttgag aagcaaaaag aaggacttgg aattttgaaa caaagcttag
    17221 aaaaagcgac tgatcttttt tctggcgagg atgaatttgg ctaccataat acctttatga
    17281 attttactaa acaatcccat gatattgaac tgggtatcac aaagactaac accgaagttt
    17341 caaatcaagc taatctttcc aatagcagtt catcagctat tgaacaagaa attacaaaag
    17401 ttcaacaaca aattggagaa tatcaagagt tgagagatgc tatcataaat aacagagcac
    17461 gcttaccaac tggcaatccg caccagtcaa ttttgaatcg ttatcttgta gcctcacaag
    17521 gacaaacaca aggaacggca gaggagccat ttttatctca aattaatcaa agtattgcag
    17581 gtctggaatc atctatcgca agcctcaaaa ttcagcaagc tggtatcgga agtgtagcaa
    17641 cttatgataa cagtttagca accaaaattg aagtactccg cactcagttt ttacagacag
    17701 cctcacagca acaactaact gtggagaatc aattaacaga attaaaagta caactagatc
    17761 aagccacaca gcgtttggaa aacaatacct taacctcccc aagtaaaggt atcgttcatc
    17821 tgaacagcga atttgaaggt aaaaatagaa ttccaactgg tacagaaatt gctcaaatat
    17881 tccctgtcat cacagataca agagaagtac taatcactta ctacgtatct tctgactatc
    17941 tacctctact agataaagga caaactgtaa gattaaaact ggagaagatt ggaaatcacg
    18001 gcaccaccat catcggccaa cttcagacaa ttgatcaaac tcctaccaga acagagcaag
    18061 gaaatctctt taaattaacc gctcttgcaa aactatctaa cgaggatagt aaactcatcc
    18121 aatatggctt acaaggtcgc gtcactagtg taactacaaa gaaaacatat tttgattatt
    18181 tcaaagataa aattttaaca cattctgatt aattttcaga taacactcta taactattta
    18241 ttatcttatc aaaaaggaga atcataacat ggataagaaa caaaacctaa cttcatttca
    18301 agaactaaca actaccgaac tcaaccaaat tacaggtgga ggattgtggg aagatttatt
    18361 atataacatt aatagatatg ctcattacat cacataagaa cttcatcatc caatacaact
    18421 ataaaaaaat aagaccgaga aacaagtact ctcggtctta tttttcatca ttctgtatgt
    18481 atcacagtaa gtacctgacg aaagacttga ttttgacagg tggtatttag actggtatta
    18541 ggatggcttt ccacaatctt catgacggta tagagaccaa ctcctctctc ctccccttta
    18601 gaactggctc caaaggagaa gatttcagaa atatcgatgc cctcttcttt gatggagttt
    18661 tcgatgataa aggtctcctg tgctccattt tttaaaaagg cgattgaaac atgaggttga
    18721 ctagcttcca cactggcttc aatagcattg tcacaaagga tagacacaat ggttagaaaa
    18781 tcaagtagac tcatcccctc gacctgaatc tcctcaggaa cttcgacatt aaagacaatg
    18841 ttcttatctc tggcttttaa aaatttccct gctagaagac ttttgagggc tttatcacga
    18901 atatttacca atctgcccag gtcatattta ttgttctgca atttctgact ggaatccttt
    18961 aagacggagc catagacctc ttttatctgc tccatatcct cctcttcaat gcccagacgt
    19021 aagctagtca agaggttggt ataatcatga cgaaagctcc gtacttcctt gtaaagctcc
    19081 tctatatgcc gactatagcg ttccatatct ctatagcgca gggcctgctc ttgttccaat
    19141 ctctcataga gtttttcctt caaataggta tccaatttct tgataacccc cataaaaaag
    19201 agtaggtaaa agactaggat gagatggcga acagtctttg attgaatact ttgttcatat
    19261 tcaaaaaaag acagactttc catgactaaa tagtagccac ccattatcca gttaatctga
    19321 gtcagggact tttgaaaggc tttatcgaga atctcctttc tcaagctagt aaaatcgtag
    19381 tccaaccatt tcaaaaaagc tagagaaatg aagaaattga aaattattat acataaccca
    19441 gtaaatgagt agccatcata tacttgccct tgtcccaaaa atggaagcac aaaataggag
    19501 actcctctat aaaagagatt caccaatatc attggaaaga gaccataaaa gaaaaggagt
    19561 tttttaggaa gccctctcaa taataagaaa gataagccta tgccgtacaa gggttccata
    19621 aaataagata ggtaaacatt tcctactata tagctaatca tcacaaaaac aaaggccaac
    19681 agtatcttca aaagaaaggc cttaaaaatc ctctcgaaag taagatcaat tccatccacc
    19741 ttaaagaaga tgacaatttc tagtccatta gtaacaagtg tatacaacaa tatccaagca
    19801 atgttcataa attctcctag ctcagtgtaa tttattgatg gcctcagaca cttccctgac
    19861 cttataacgg gcgattagac aacttccacc attgggaaag aaaagcagtt tttctttctt
    19921 atccaaatgc accacatttg caggattgat gagaaaagag cggtggcact gcaagagacg
    19981 gggctcctgc ttgaaaacct cctctaaact cgctgtaaat tccagcctgt ctgtcttggt
    20041 atagagaata acacgatggg ctctgggcga cgtttcgaga tagtaaacct ctttaaaagg
    20101 atactgaaat tgggcaaatt ttgatttaaa gtaaaagcaa tcttccgcca gacttttact
    20161 atcttgacta ttggcataga ggagggctgt ctcgatccga gattcaaact cctctgctga
    20221 caaggcctta tcaatgtagt tcaaagcaga cacttggtag cgaaaagaca ggggcataaa
    20281 ctccgagtga gtcgtcacaa agacaatcag ggcataagga tcccgatccc gaatctttct
    20341 agccacttcc agtcccttca tctcttcatt tcgaatctca atatccaaaa agaatagctg
    20401 atgggccccc ttctcatgca cttcagccag cagttggtcc ggcttgccaa atacctcaaa
    20461 agagctagga atgatatgat gtgctttcaa aagtttctca atcgtcgttt caattctagt
    20521 ctgttgggaa aaatcatcct ctaaaacaaa tattctcatc tttttactct ccttatttta
    20581 accatttttg acgaatttct ctatagcgac gtctggcata cttgacagcg tattgacctt
    20641 cttctccgag aaaaaggatt ctttcttgaa aatcaatcga ttttaattta tcaagattaa
    20701 ccaaacaatt tcgatgacat ctcatcaagg tttccccaca ttggttctca agattactta
    20761 aattttgaag catattaaaa ctagcttctt ctgtaacaat ctgtacggta tgggctttag
    20821 ttggatgtgt ttggatatag tagatatcgt cgacgtttac tttatagact gttttctgcg
    20881 tctgaataat catatgtttc attggattct cctcctaaga aaagaataac agaaaaggtc
    20941 tagcccaagc ccacccaatc ctaaacagtc tttgaaagct cctaaaagga ttatttttct
    21001 acaacatcat gatgagctta caactatttt atcataaaat tcactcagcg caattcaaga
    21061 catttcaatg acaattaaag atttgaataa aaaaaaagaa ttaaaaatga taaactaaca
    21121 gtatcaaaac acagttgcca gaagtaagac tggcacccag attaaaggag gcattcccat
    21181 gacagataca gaccccatca aaagagctca tactttgatt actgacttaa acaaagccta
    21241 ccaagcatgc aaacaggcaa gcgctgacga cgtccgcttt caggagcaat taaactctat
    21301 tcttggtttt ctagccaagg ctgaaacagt ggataatcga ttcttgattg aactagaaaa
    21361 attttaccag acttccagtc ttctcatggg actcagcgct cttgatccag atgctccaac
    21421 tcgcgccgct tggcgggcct atgaccgctt ccactttgac caagtcaaga ccaagttaat
    21481 actcaatgaa aatcaaagag caaactagga agctagccgc aagctgtact tgagtacggt
    21541 aaggcgacgc tgacgtggtt tgaagagatt ttcgaagagt ataagtctct acggaccaac
    21601 cattatcctg tagtaacaaa aaagaagctg agacagactg aactcaactt cttttttagt
    21661 gtcgtatcag caatgttagt cctgcatctg acgttttacc tgataaggca aatacaagac
    21721 tagtaaaacc aaaccagctc ctagtaaggc tagaagggcc agtttttctt ggaaggtaat
    21781 caacccaaca actaattcca caagtaaaac aaaactggtc aatcctcgaa ctacctcctg
    21841 taagcctttt tccttttgcc ccttgtccag cggaaagagt tgggtcaaat actggtagtc
    21901 aaaggcatga tagagggcca gcaactggaa gagcaagagg tagttaaaga gaactaccac
    21961 tgctgtcgca atccaagctt gctcgataaa aacctgcgcc agtacggaaa gtaagagaag
    22021 acgaagactg agagcaaaga ggtcgccatt tcgcagataa gaacgcagat agagattttg
    22081 ccaaatcttc ccaggcacct tctgaacagc ctttaaaata aagtccagat aggcacgacg
    22141 cttaacgctg tttgaaattc ccttgacctg cgtaaagagg gcaaagaaac gaagcaagac
    22201 ttgcttacgc ttgctttctt gagaaataag atagtcccag tccagtccag tttcagtgaa
    22261 aaatttgctg gccttttgac aaaagtggaa atattttcct acccccaata aaagcacata
    22321 gagcagaaaa actggcaagc cataacccat tgctaaaaat aaaggcgcaa ataaaagcaa
    22381 gaagagggtc tggacaaaaa tccaaaagac tagggaaatg ccagtttgac gcttgagatg
    22441 gagcttaatt tcctcttctc caactaagag aaagagcttg tctggagcct ccatataggt
    22501 ggcaattcct ccccaaagta aaagtaaaac agacgtaatt cctacaaaca aaaggatagg
    22561 ccaatgattt tcaggaaaat gttgtaagag ttgactgtac tggtaggcta gaaagcccaa
    22621 caggacaagc aggaacaaga caaagtggtc attgagcaca tagcgcagat aaccaagaca
    22681 ctccttacga aaggcctgct ttctctttaa aaacaagtct ttcataggtc ctcctctttt
    22741 gtcagagcca agtaaatatc attcaaacta gcctcaggca tatcaaaggc ttcgcgtagt
    22801 tgcaggagat tgcctttggc acgcacctct cccttgtgaa gaatgacaaa ggcatcacac
    22861 atcttctccg ccgaatccag cacgtgggta ctcatgagaa tagacttgcc cttttgcttc
    22921 tccacttcca aaagctgaat caaatcagaa atagctagcg gatcaagacc aaggaaaggc
    22981 tcatccacga tgaaaagact tggatccacc acaaaagcac agataatcat gaccttctgc
    23041 ttcatccctt ttgaaaaatg aacagggaac cagtctaatt tctggtccag acggaacatc
    23101 tttaacaagg gctctactcg ttcgaaagcc actttttgct caataccgta agccatagca
    23161 accgtttcga tatgctctct gagggtcaat tcctcataca gactaggcgt ctcaggaatg
    23221 tagccaatct gcttgcggta gctagtcgca tctccttgca tagtcaggcc attgatattg
    23281 atggagccac tataaggtgc caacagaccg ataatctcat tgatcgtcgt tgatttccca
    23341 gcaccattga gaccaatcaa accgaccaac tgcccacttt caacagtaaa ggacacatct
    23401 ttcaaaacag gaacatgaac atagccacct gtcaggtttt taatttctaa catattttct
    23461 ccaaatctgg tataatgtag ctatattata tcaaaattca gtacagtaga ggtagatttt
    23521 atgtcagatt gcattttttg taaaatcatc gcaggggaaa ttcctgcttc aaaagtatat
    23581 gaagatgagc aggtccttgc ctttcttgat atctctcaag taacactagg acacaccttg
    23641 gtcgtgccaa aagaacacta tcgcaatctt ttggagatgg atgctacgag cgccagccaa
    23701 ctctttgccc aagtaccaaa agtagctcaa aaagtcatga aagtcactaa ggctgctggt
    23761 atgaatatca tttccaactg tgaagaagtc gctggtcaaa cagtttttca tactcacgtt
    23821 caccttgtgc ctcgctacag tgctgacgat gacctcaaga ttgattttat cgcccacgaa
    23881 ccagactttg acaaacttgc tcaagtcgct gaaaccatca aaaacgctta aggagttgct
    23941 atgaaattat ccaacctact gctatttgca ggagctgcag ccggaagtta tctggttaca
    24001 aaaaatcgcc aaaccatcac agatgaagtc ttgaatacca ctgaccgcgt tcaagctatc
    24061 aaggacgatg tggatattat ccaaaacagc ctgcaaatca ttaaccagca aaaagaactt
    24121 atcaaggaat accaagaaga cttgacttac aagtttaagg tcttggaaaa ggatatccag
    24181 actagactag ctgtgataaa agaaatgcag ggaactgaag ataagtaaaa agagcccccc
    24241 ggctcttttt taaaacgtaa acaagttata gtgaattgaa tttagaatag cacaccatag
    24301 tttctaaagc attgttagag attactttaa aatcctctta tcaatttgtt catattctat
    24361 tcaatttgtt catattctat ttcaatctat tatatatatc ccatcaacta tgcatcataa
    24421 tttaggtaac tcatactcaa taaaaatcaa aaagcaaact agaaagctag gcacagactg
    24481 ctcaaaacac cgtttt
//
LOCUS       DBERXF010000036        23862 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.36, whole genome shotgun sequence.
ACCESSION   DBERXF010000036 DBERXF010000000
VERSION     DBERXF010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23862
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.36"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(191..2449)
                     /locus_tag="ACL8JK_001580"
     CDS             complement(191..2449)
                     /locus_tag="ACL8JK_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS1786437.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGFA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2678..2908)
                     /locus_tag="ACL8JK_001581"
     CDS             complement(2678..2908)
                     /locus_tag="ACL8JK_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HGS1786438.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3098..3781
                     /locus_tag="ACL8JK_001582"
     CDS             3098..3781
                     /locus_tag="ACL8JK_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1786439.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQVGILGVDLSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KRMGQGDKK"
     gene            3781..4515
                     /locus_tag="ACL8JK_001583"
     CDS             3781..4515
                     /locus_tag="ACL8JK_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1786440.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESKAVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4669..5526
                     /locus_tag="ACL8JK_001584"
     CDS             4669..5526
                     /locus_tag="ACL8JK_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGS1786441.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTEKLKEETGLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGFRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLSKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5669..6541
                     /locus_tag="ACL8JK_001585"
     CDS             5669..6541
                     /locus_tag="ACL8JK_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGS1786442.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPDLHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     GDNAFGEDLVKQVFAGLKQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLSKIMK
                     IICQQDRVSKDKLV"
     gene            6823..7506
                     /gene="rpiA"
                     /locus_tag="ACL8JK_001586"
     CDS             6823..7506
                     /gene="rpiA"
                     /locus_tag="ACL8JK_001586"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGS1786443.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7520..8731
                     /locus_tag="ACL8JK_001587"
     CDS             7520..8731
                     /locus_tag="ACL8JK_001587"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGS1786444.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8733..9275
                     /locus_tag="ACL8JK_001588"
     CDS             8733..9275
                     /locus_tag="ACL8JK_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HGS1786445.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVYYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9291..10100
                     /locus_tag="ACL8JK_001589"
     CDS             9291..10100
                     /locus_tag="ACL8JK_001589"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGS1786446.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10576..10971
                     /locus_tag="ACL8JK_001590"
     CDS             10576..10971
                     /locus_tag="ACL8JK_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase family protein"
                     /protein_id="HGS1786447.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            10981..11556
                     /locus_tag="ACL8JK_001591"
     CDS             10981..11556
                     /locus_tag="ACL8JK_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HGS1786448.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            11581..12093
                     /locus_tag="ACL8JK_001592"
     CDS             11581..12093
                     /locus_tag="ACL8JK_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin C-terminal
                     domain-containing protein"
                     /protein_id="HGS1786449.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12749..13459
                     /gene="deoD"
                     /locus_tag="ACL8JK_001593"
     CDS             12749..13459
                     /gene="deoD"
                     /locus_tag="ACL8JK_001593"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGS1786450.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13482..14006)
                     /locus_tag="ACL8JK_001594"
     CDS             complement(13482..14006)
                     /locus_tag="ACL8JK_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HGS1786451.1"
                     /translation="MKIAIIGYSGSGKSTIAEKLSNYYSIPKLHMDTLQFQPGLQDSD
                     CEWMLTEIKNFLTKYKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAVDCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14059..14295)
                     /gene="rpsT"
                     /locus_tag="ACL8JK_001595"
     CDS             complement(14059..14295)
                     /gene="rpsT"
                     /locus_tag="ACL8JK_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGS1786452.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLVK"
     gene            complement(14363..15283)
                     /gene="coaA"
                     /locus_tag="ACL8JK_001596"
     CDS             complement(14363..15283)
                     /gene="coaA"
                     /locus_tag="ACL8JK_001596"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGS1786453.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15473..15876
                     /locus_tag="ACL8JK_001597"
                     /pseudo
     CDS             15473..15876
                     /locus_tag="ACL8JK_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16083..16673
                     /locus_tag="ACL8JK_001598"
     CDS             16083..16673
                     /locus_tag="ACL8JK_001598"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS1786454.1"
                     /translation="MSKMYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDF
                     GSQLLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEK
                     NNAKATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQ
                     KKQGAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16670..17947
                     /locus_tag="ACL8JK_001599"
     CDS             16670..17947
                     /locus_tag="ACL8JK_001599"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGS1786455.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17965..18627
                     /gene="deoC"
                     /locus_tag="ACL8JK_001600"
     CDS             17965..18627
                     /gene="deoC"
                     /locus_tag="ACL8JK_001600"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGS1786456.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGDLKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18614..19003
                     /locus_tag="ACL8JK_001601"
     CDS             18614..19003
                     /locus_tag="ACL8JK_001601"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGS1786457.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NVSYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19094..20146
                     /locus_tag="ACL8JK_001602"
     CDS             19094..20146
                     /locus_tag="ACL8JK_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HGS1786458.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDIANKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20290..21825
                     /locus_tag="ACL8JK_001603"
     CDS             20290..21825
                     /locus_tag="ACL8JK_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1786459.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21818..22876
                     /locus_tag="ACL8JK_001604"
     CDS             21818..22876
                     /locus_tag="ACL8JK_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1786460.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22879..23835
                     /locus_tag="ACL8JK_001605"
     CDS             22879..23835
                     /locus_tag="ACL8JK_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1786461.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         6946 a         4314 c         5417 g         7185 t
ORIGIN      
        1 taagatgaga acaaatcgat tgggaaagta aaattaattt ctataaatgt tttagcaatt
       61 gtttcgtact atttcagatt cagtctacta tatatcataa tggacaaagg gcaagctgtc
      121 aagaaattac agttatttta gtaaaaaaag aagcagaaaa atttcatttt ctactccttt
      181 tctataggat ttatttttct ttttcagaac ttttaacttc agcttttttg gcagatttaa
      241 tctgaatgtt tcccttgcta gtcataactg ctttgagatc tttttcgctt ggattttcaa
      301 ggtagtagtc agtgattgtg tcctcaatat agtcttgaat agtccgacga agtgggcgtg
      361 ctcccatttt tggatcataa cctaggtcaa ccaacttttc cttgaccttg tcagttacat
      421 ccaaacgaat gttgttgcta gagaggcgct tgttaacatc tgctagcatg agctcgacaa
      481 tctgaaggag gttatccttg ctgagagcct taaattcgat aatgccatca aaacggttca
      541 taaactctgg gctaaagaag ttaccgagtt caccgaggac agaattggta cgtccttctc
      601 tagcagcacc aaatccaacg ctagcttcgg tctttcctgt acctgcattt gaggtcatga
      661 taatgatggc atccttgaag ctaacggtgc gtccttgccc gtctgtcaaa cgaccatcgt
      721 ccaagacttg aagaaacatg tgcataacat ctgggtgagc tttttccact tcatcgagaa
      781 ggatgagaga atatggattg tggcgaactt tttcagttaa ttgaccagcc tcatcatagc
      841 caacataacc tggaggggcg ccgaccaact tagccacact atgtttttcc atgtattcac
      901 tcatatcaaa gcgaatcata ctatcagcaa aaccaaaaag ttcgatagcc agttgtttgg
      961 aaagttctgt cttaccgaca ccagttggcc caacgaagag gaagcttccg attgggcggt
     1021 taggggtacc aagtccgaca cgattacggc gaatagcctt ggcaatctta tcgactgcat
     1081 catcttggcc aataacatga gacttgagat cttcggctag atggatgagt tgagattgtt
     1141 ctttctcttt caaatcacca acagggatat tggttttctg ctcgataatg tgctcaatag
     1201 ttttctcgct gatgatagga gtatcctggt ctgtgatctt tttcttttgc atttccttat
     1261 acttggcaat ctggtcgcgg aagtaggccg ccttctcaaa atcttcttct cgtgtagctt
     1321 gagacttgag attttcagcc tcaatcaagc gctgatcaat tactttagga tccacaaaat
     1381 tcaaggtcaa gttcatctta gaaccagctt catctaggag gtcaatggcc ttgtcaggca
     1441 agaagcgatc ttggatgtag cgattggaaa gagttgcagc tgcttcaatc gcagcatctg
     1501 tatattgaac gtggtggtaa tcttcgtatt tcttttgaat ccctttgaga atagtgattg
     1561 tttcgtccac cgttggttca tcgactttaa caggctgcat acgacgctcg agggcagcat
     1621 ccttttcaat gatacggtat tcattgaggg tagtagcacc gactagttgc agttctccac
     1681 gagcaagggc tggcttgagg atatttcctg cgtccatatt accatcactc gcagaaccag
     1741 caccaacaat ttcatggatt tcatcgataa agaggatgat gtcttcacgt ttgcgaattt
     1801 cttccatgag tttttgcatg cgttcttcaa attgtcctcg aatccccgtt ccttgaacta
     1861 agctaaccac atccagacgg atgacttgtt taccttggag tttatgtggc acatcgccat
     1921 cgacaatttt ctgagctaga ccttcgacaa cggccgtttt tccgacacca ggttcaccga
     1981 taaggacagg attattcttg gttctacgat tgagaatctc gatgacacgg ataatctcat
     2041 cgtcgcgccc aataacgggg tcaatgtctc cacgacgggc aatttcagtt acattaatac
     2101 caaattcttc cagcaggcct ttttcttggc taggtggcgg agtttgagca gatccacgat
     2161 tttgggaacc ataaccgccg tttccaccgt aacctccacc tgattgggtt gggggaatag
     2221 gaggagtatt gctagaaggt ctgaaattgt ttagatcatt gaagaaatca ccaaagggat
     2281 cgaagtcacg attgttcaga tccgtcatac ctttgaagag gctattgtta ggatctgttt
     2341 tgataatctt atagcagttt tgacagaggt caatttgttt ttgttttcca ttgagattgg
     2401 tgtaaagatg aattgttgag tcgttaattt tacagttttg acaaagcata catctacctc
     2461 atttctttct ttagcctgac ttgtttaaag gtcaaaaata gtcaaattct atactctcat
     2521 tataacagga ttggggtgta aagcaagtaa aaagattgaa gctttgagaa gttgttacaa
     2581 tgaaaatttt tgtgaatttg gactataaaa aaatcctatt tgtgagacaa aaaggatttt
     2641 acttagacat gcagggacaa tcccagcttg ttttagatta gtagagaagt tcgtaaattt
     2701 ccattgcgat taagtcaatg ctatcaaacg tatacgtttc gcgatcttct acgtcacgaa
     2761 gggtaaagat tgggccgttt tcttcgtcgt ggctgtacgc aacttctgca acaacaactc
     2821 cttcgcgttc aaaattacgt tttaaatttc cgccatcgtt tgccattgct tcaaggcggt
     2881 tgatgattct aaccaaatgt gattccattt tgattctcct tcatttctta tcgttactat
     2941 tttaccataa aggaggccaa cttgactaga aaaaactaag atttctcgct aattctgcta
     3001 gtttaaagat ttttaaataa attggataaa aaatttaaat tttaattcaa aacatgttat
     3061 aatcatacag tattctattt tagaaagcag tgtgactatg aatttttctt ttttacctaa
     3121 gtatttacct tattttaact atggggctgt tgtgacgatt cttatttcta tctgtgttat
     3181 ctttttggga actattttgg gtgttgtctt ggcttttggg caacgttcaa agtttaaacc
     3241 gcttgtttgg ttggccaact tgtacgtttg gattttccgt gggacaccga tgatggttca
     3301 aattatgatt gcctttgctc ttatgcatat caatgctccg actattcagg ttggaatttt
     3361 aggtgttgat ctttctcgtc tgattccagg gattttgatt atctctatga acagtggtgc
     3421 ttatgtttct gagactgttc gtgccggaat caatgcagtt cctaaggggc agttagaggc
     3481 ggcttattct ttagggattc gtcctaaaaa tgctatgcgc tatgtaattt taccacaagc
     3541 tatcaaaaat atcttgccag ctttggggaa cgaatttatc accattatca aggacagctc
     3601 cctcttatca gctatcggtg ttatggagtt gtggaacggg gctacaacag tttctacaac
     3661 aacctatcta cctttaacac cacttttatt tgcagctttt tattacttga ttatgacttc
     3721 tattttgaca gtagccttga aagcttttga aaaacgtatg ggacaaggag ataagaaata
     3781 atgacagaaa ccttgataaa aattgaaaat ttacataaat catttggaaa gaacgaagta
     3841 ttgaagggca tcaacctcga gattaaaaga ggagaagttg tcgttatcat cggtccttca
     3901 gggagcggga aatctacctt gcttcgctct atgaatttgt tggaagaagc gaccaagggt
     3961 aaggttatct ttgagggagt cgatattacg gacaagaaga atgacctctt tgccatgcgt
     4021 gagaagatgg gcatggtttt ccaacaattt aacctctttc ctaatatgac tgtgatggaa
     4081 aatatcacct tgtcacctat caagaccaaa ggtgagagca aggctgttgc tgagaagaga
     4141 gcccaagagc ttttggaaaa agttggtttg ccagataagg cagatgctta tccacagagt
     4201 ttgtcaggtg gtcagcaaca acggattgcc attgcgcgtg ggttggccat ggaacctgat
     4261 gttttgctct ttgacgagcc aacttcagca ctagatcctg agatggttgg agaagttctg
     4321 gctgttatgc aagatctagc caagtcagga atgaccatgg ttatcgtaac acatgagatg
     4381 ggatttgccc gtgaggtggc agatcgtgtc atctttatgg cagacggtgt ggttgttgaa
     4441 gacggaacac cagaacagat ttttgaacaa acccaagaac aacggactaa agacttcttg
     4501 agtaaggttt tataatctat tttaaaattt caagacaaga ttagtgaaaa gctcaaccag
     4561 agctttttct tatagtttga aactatagga ttgcctagga aagaagtgtt agagggtgct
     4621 ggcagttttt ggtataatgg aagatatttg aaagaaaaga gaagtgatat gacacagatt
     4681 attgatggaa aagctttagc ggccaaattg caggggcagt tggctgaaaa gactgaaaaa
     4741 ttaaaggaag aaacaggtct agtgcctggt ttggtagtga ttttggttgg ggacaatcca
     4801 gccagccaag tctacgttcg caacaaggag aggtcagctc ttgcagctgg tttccgtagc
     4861 gaagtagtgc gagttccaga gaccattact caagaggaat tgttagacct gattgctaaa
     4921 tataatcagg atccagcttg gcatgggatt ttggtccagt tgccattacc aaaacatatc
     4981 gatgaagagg cggttttatt agccattgac ccagaaaagg atgtggatgg tttccatccc
     5041 ctaaacatgg gacgtctttg gtctggacat ccagtcatga ttccctcgac acctgcagga
     5101 attatggaaa tgttccatga atatgggatt gacttggaag gtaaaaatgc agtcgtcatc
     5161 ggtcgatcca atattgtcgg aaaacctatg gcccagcttc ttttggcaaa gaatgcaaca
     5221 gtaaccttga ctcactcacg tactcataat ctttccaagg tggctgcaaa agcagatatt
     5281 ctggttgttg caatcggccg cgccaagttt gtgactgctg actttgtcaa accaggtgcg
     5341 gtagtcattg acgttgggat gaaccgcgat gaaaatggta agctctgtgg ggatgttgat
     5401 tatgaggcgg ttgccccact tgctagccac attacgccag tccctggagg tgtcggtcct
     5461 atgaccatta ctatgctgat ggagcaaacc tatcaggcag cacttaggac attggataga
     5521 aaataagaga aacattcgat taatagagtg tattttctat agctatatct aacaatggca
     5581 gaaatgaata ttaaatttta gatataagat tacaaaagga ggtctgcgtc tcctttttat
     5641 tgtataataa aagtgagagg aaaaaaggat gaaagtgatt aatcaaacct tattagaaaa
     5701 agttattatt gaacgttctc gttcaagtca taaaggagat tatggtcgtc tgctgctgct
     5761 tggtggtact tatccttatg gaggtgccat catcatggct gctttagcag ctgtaaaaag
     5821 cggtgcagga ttggtgaccg ttggaacgga cagggaaaat atcccggatc tgcacagcca
     5881 tttacctgag cctatggcct tttctcttca agaccagcaa ttgttaaaag agcaattgga
     5941 gaaggcagaa gttatcttgc tggggcctgg tttaggagac aatgcttttg gagaagattt
     6001 agttaaacag gtctttgctg gcttaaaaca gaatcagatt ttgattgtag acggaggtgc
     6061 cttgaccatt cttgctagga caagtttgtc atttccctca agccagctta tcctaactcc
     6121 tcaccaaaaa gaatgggaaa aattatctgg aattacgatt gaaaagcaaa aggaagatgc
     6181 aacggctagt gttctgactt ccttccctca aggaacaatt ttggtggaga aaggcccagc
     6241 tactcgtatt tgggaagttg gccaatctga ttattaccag ttacaggttg gtggtcctta
     6301 tcaggcgact gggggaatgg gagatactct ggctgggatg atcgcaggat ttgtaggcca
     6361 attccgacag gccagtctct acgagcgtgt ggcagtagcg acccatcttc attcagccat
     6421 agcccaagaa ctatctcaag aaaattatgt ggtcttaccg acggaaatca gcaggtatct
     6481 ttccaaaata atgaaaatta tttgtcaaca agatagggta agcaaagata aacttgttta
     6541 aaatagacag ataaatctac ttccttctct taatttatga ttcttgaaat gcgcctgctt
     6601 taaggctaaa ctagacgtat caaagttaag agtttgtttt tgtaactgga aagagatgaa
     6661 caaatcaaat acataaaaga taaactcatt tttattcgtt tggtaaaaat aaaatgcata
     6721 tttttaaaga aagattgatg gaaaatgtag atttgatgtt tttacttgaa taaaaagcgg
     6781 tttcatagta aaataagaac tgagaatgat ggaggtaaat cggtggaaaa tctgaagaaa
     6841 atggcaggta tcaaggctgc tgagttcgtg agcgatggaa tggtcgttgg acttggaaca
     6901 ggctcgactg cctattattt tgtcgaagaa atcggtcgtc gtatcaagga agaaggattg
     6961 cagattacag ctgtaacaac ttctagtgtg accactaaac aggcagaagg ccttaatatc
     7021 ccgctcaagt ctattgacca agtagacttt gtcgatgtga cggttgatgg cgcggatgaa
     7081 gtggatagtc agtttaatgg aatcaaaggc ggtggtggtg cccttctcat ggaaaaggtg
     7141 gtcgcaacac catcaaaaga atacatttgg gtggtggatg aaagcaagct ggtcgaaaaa
     7201 ctaggtgctt ttaaattgcc agtagaagtg gttcagtatg gtgcagagca ggtctttcgt
     7261 cattttgaac gagctggcta caaaccaagt ttccgtgaaa aagacggcca acgttttgtg
     7321 acggatatgc agaattttat cattgacctc gccttggatg tcattgaaaa tccaattgct
     7381 tttggacaag aattggacca tgtcgttggt gttgtggagc atggtttatt caaccaaatg
     7441 gtggataagg taatcgttgc tggacgagat ggagttcaga tttcaacttc aaaaaaagga
     7501 aaatagaagg gggcataaga tgtctaaatt taatcgtatt catttggtgg tactggattc
     7561 tgtaggaatc ggtgcagcac cagatgctaa taactttgtc aatgcagggg ttccagatgg
     7621 agcttctgac acactgggac acatttcaaa aacagttggt ttgaatgtcc caaacatggc
     7681 taaaataggt cttggaaata ttcctcgtga aactcctctt aagactgtag cagctgaaag
     7741 caatccaact ggatatgcaa caaaattaga ggaagtatct cttggtaagg atactatgac
     7801 tggacactgg gaaatcatgg gactcaacat tactgagcct ttcgatactt tctggaacgg
     7861 attcccagaa gaaatcctga caaaaatcga agaattctca ggacgcaagg ttattcgtga
     7921 agccaacaaa ccttattcag gaacggctgt tatcgatgat tttggaccac gtcagatgga
     7981 aactggagag ttgattatct atacttcagc tgaccctgtt ttgcagattg ctgcccacga
     8041 agacattatt cctttggatg aattgtaccg tatctgtgaa tacgctcgtt cgattaccct
     8101 tgagcgtcct gcccttcttg gtcgcatcat tgctcgccct tatgtaggtg aaccaggtaa
     8161 cttcactcgt acggcaaacc gtcgtgactt ggctgtatct ccattttccc caactgtttt
     8221 ggataaattg aatgaggctg gtatcgatac ttatgctgtg ggtaaaatca acgatatctt
     8281 taacggtgct ggtatcaacc atgacatggg tcacaacaag tcaaatagtc atggaattga
     8341 tacactattg aagactatgg gacttgctga gtttgaaaaa ggattctcat tcacaaacct
     8401 agttgacttt gatgcccttt acggccatcg tcgtaatgct cacggttacc gtgattgctt
     8461 gcatgagttt gatgaacgct tacctgaaat tatcgcagct atgagagaga atgaccttct
     8521 cttgattact gcggaccatg gaaatgaccc aacgtatgca ggaacggatc acactcggga
     8581 atatattcca ttgttggcct atagccctgc ctttaaagga aatggtctca ttccagtagg
     8641 acattttgca gatatttcag cgactgttgc cgataacttt ggtgtggaaa ctgctatgat
     8701 tggggaaagt ttcttagata aattggtata agatgacgcg ctatgctttg ctggtgagag
     8761 gtatcaatgt tggtggtaag aataaggtcg tcatggcgga gcttcgtcaa gaattgacaa
     8821 acttgggact ggaaaaggtt gagagctaca tcaacagtgg caatattttc tttacttcga
     8881 tagattccaa agcccaattg gttgaaaagc tagagacttt ctttgcagtc tattatccat
     8941 ttattcagag cttttcttta ctgagtctag aggactttga ggcggaactt gaaaatctac
     9001 cagcttggtg gagcagagac ttggcacgaa aagattttct cttttacact gagggtttgg
     9061 atgtggacca agtcatcgcg acagttgaaa gtttagagct gaaagatgaa gtgctttatt
     9121 ttggaaaact tgggattttc tgggggaaat tttctgaaga atcctattct aagactgcct
     9181 atcataagta cttgctgaag gtgcctttct accgccacat tactattcgt aatgctaaaa
     9241 cctttgacaa aattggtcaa atgctaaaaa aataataaag gagacacaca atgacatttt
     9301 taaacaaaat ccatgaaact gctactttcc tgaaagaaaa gggaattgca gcccctgagt
     9361 tcggtctaat ccttggatca ggacttggag aattggcaga agaaatcgaa aatccagttg
     9421 tagtagacta tgctgagatt ccaaactggg gccgttcaac agtagtcggt catgctggta
     9481 aattggtata tggtgaactg gcaggtcgca aggtcttggc tcttcaaggg cgtttccatt
     9541 tctatgaagg gaatcctctg gaagtggtga ctttcccagt tcgtgtgatg aaagttcttg
     9601 gatgtgaagg tgttattgta accaatgcag ctggcggtat cggatttggt cctggtacct
     9661 tgatggctat ctcagaccat atcaacatga cggggcaaaa tccattgatg ggtgaaaact
     9721 tggatgactt tggcccacgt ttcccagata tgtctagggc ttacacacca gaataccgtg
     9781 ccactgccca tgaagtggct aaaaaactta atatcaagct tgatgaaggt gtctatatcg
     9841 gagttactgg tccgacttat gaaacaccag cagaaattcg ttcctataag acactgggag
     9901 cagatgcagt tggtatgtct acggttcctg aagttatcgt ggcagcccac tctggcttga
     9961 aagttctggg aatttcatgt atcactaact ttgcggccgg tttccaagaa gaactcaatc
    10021 acgaagaagt tgtagaagtg actgaacgtg ttaaaggtga tttcaaaggc ttgcttaaag
    10081 cgattcttgc tgaattgtaa gaaaaaagat ttaaaagggg gagtgcctct gtcttttcag
    10141 gattgactgc ctatccgtat taaagaagaa acagaggaat actatgagct tcttcctgct
    10201 cttataactg aaagaagcgg aagaataggt atgtctgatc tgatagccag cattgtgaag
    10261 gacaagattc taggatacta gcattagctt cctagccaag cagactagta tgataaggag
    10321 agatgagaat gaattgactt tctgaatttc tcagtcttat catatatagc acaatgagat
    10381 ttcgcttgag tctgcttgta aataaacgaa aagaaagata agaaataatg aaaattggtc
    10441 aacgaattat gcgctttggc ataaaaaatt aagtatcgga gttgtatctg ttgtagtcgg
    10501 ctttgatttc tagctccagc tggaatttca gccaatgaag taaagcaaga tgtaacatct
    10561 gaagtggtaa taggtgtgct agattctaag gaggaattga aagagtcaga aaatgatgct
    10621 ccaaaactag aaactcctct tagagaggag ccaagactag ctcctcaaac gcttccggaa
    10681 gcaagtgaag ttcttgaaaa caaaagggaa gagtcaaaag tagagataac agagccagct
    10741 caagcggatg atatccgcaa ggttgttggg gaattagcca aggatataag tattactaag
    10801 ttgtatatga caggtcattc tcttggaggc tacctagctc agattgcagc ggttgaagat
    10861 taccaaaaat atcctgattt ttataaccat gtattgagga aagtgacaac tttcagtgct
    10921 cctaaagtga ttacttccag aactgtttgg gatgctaaga atggtttctg agatgttggt
    10981 ttggaaagtc gtaaattagc tgttagtgga aaaattaagc attatgtggt tgataatgac
    11041 aatgttgtga ctcccttgat tcataataat cgtgatattg ttacatttac aggtaattca
    11101 cgctttaaac accgttctcg tggctatttt gaaagtccaa tgaatgatat tcctaacttt
    11161 aatattggta aacaagctac cttggataaa catggttatc gtgatccgaa attggataaa
    11221 gtgcgattct ttaagaaaca ggctctacct caatcttcta gtcaaccaag cgctgaacca
    11281 atggaaaata ttgccttagg aaaacaggtt actcaaagtt cgacagcttt cggaggagat
    11341 gctagaagag ctgtggatgg caaagtcgat ggtaactatg gtcacaattc tgtcactcat
    11401 acaaacttcc aatctaagcc ttggtggcaa gtagatttgg ctaaagaaga aaccattcgc
    11461 caaatcaata tttacaaccg aacagacact gcccaggata gattggcaaa ctttgatgtc
    11521 attcttttag acagttctgg taaagaaatt gagtgaaaac gtataatatc tcctaaagat
    11581 gtgtcagcac aaattacgat taaccataaa aaagcgcgct atgttcggat tgagctagaa
    11641 ggctataatg ccctcagtct tgcagaagtt gaagttttcc gctttatagc tacgaatgct
    11701 gaaacggcga cacaagtttc taagccagtt caaccaatca gtcagactcc tgtgaaagat
    11761 aaaacattga caattcaaca cagtggagct tacattgccc gctactccat aacttgggaa
    11821 gaagttccag tagataaaga tggaaaccaa gttgttcgta gtcattcttg ggaaggaaac
    11881 ggttgcaacc agactgcagg ttttgtcctc aacctcccaa tcaaagaaaa tatgagaaat
    11941 ctgcgagtta agattgagaa aaagacgggc ctactatgga atagatggca aacaatctat
    12001 gaaaacagac caattttagc tcaaccccac cgtaaaatta cccattgggg tacgacattg
    12061 aattccaagg tgagtgacga tgatgtcttg taatctgatg gtacaatgac agttagtttg
    12121 tctagtttat aagaaagtac tacctgagct tgaatagaac tcaggtagct ctatgaaaga
    12181 acaaaattaa tactcaatga aaatcaaaga gcaaactagg aaactagccg caggttgctc
    12241 aaagcactgc tttgaggttg tagataagac tgacgaagtc agtcacatat ataatccaag
    12301 gcgacgttga cgtggtttga agagattttc gaagagtata aacagaaagg tagagcgcgt
    12361 gttctaattt gaacacgagt agaaaacttt tctaaaaaca aaaacgaaag gatgggtaaa
    12421 ctgtattcgc tgaactgaat acgggcgact ctcctctaaa tcaaaattaa gaaagaaagg
    12481 aattgacccc accctaaaag cagtgggaaa aagatagttg atctagcgag catcgctcac
    12541 tgcgcccaac tcctattttc ccttcgcttt ttgatgggtt tggtatcttt ctcaatataa
    12601 aatataaaat aaagaaaggt agagcgtgtg ttttgatttg aacacgagcg gaaaactcgg
    12661 aaaatagata atctgactga aaaatcagga tttctcgtca ggttcctaat tttcagtcgt
    12721 tttcttctcg ctctttgtat cataaattat gtctatccat attgctgctc agcagggtga
    12781 aattgctgat aaaattcttc ttcctgggga tcctcttcgt gctaagttta ttgcggagaa
    12841 tttccttgat gatgctgttt gttttaacga agtgcgtaac atgtttggtt acactggtac
    12901 ttacaagggt cactgtgtat ctgtcatggg aactgggatg ggaatgccat ctatttcgat
    12961 ttatgcgcgt gagttaatcg tagactacgg tgtgaagaaa ttgattcgtg tgggaactgc
    13021 aggttctttg aatgaagagg ttcatgttcg tgaattagtt ttggcgcagg cggctgcaac
    13081 caactcaaac atcgttcgta atgactggcc acagtacgat tttccacaaa ttgctagctt
    13141 tgatttgctt gataaagcct accatatcgc caaaaaactt ggtatgacta ctcacgttgg
    13201 gaacgttttg tcatctgatg tcttttactc aaattacttt gaaaagaata tcgagcttgg
    13261 taaatgggga gtcaaggctg tggaaatgga agcagcagct ctttactatc ttgctgccca
    13321 ataccatgtt gatgcgctag ctatcatgac catctctgat agcttggtca atccagacga
    13381 agacacaact gcagaagaac gtcaaaatac cttcactgat atgatgaagg ttggtttgga
    13441 aaccttgatt gcagaataat tatagccaaa aaggaagccc tttatgaatt gtaggacttc
    13501 cttttcttat ccagaaattg atctagctct ctctgatttc gaagaatagt gactttatgt
    13561 gaatattctt ggcaaagttt ttggtaattt tctttttgag ttttgctacg cccatcccaa
    13621 agaatccatc tgataaactc ccagtcaaag cgttcagggc aatctaccgc catactttct
    13681 ctgacttttc cacggtattt aagataacgc ttaaaggctc taaagagaca ggtcaatggc
    13741 gaaaaattga gaaagatgat ttggtcagct tcttgcattc gttcttggta gtagcaccaa
    13801 gaataattac catcgatgac ccaagcttta tacttggtga gaaagttttt tatctcggtt
    13861 aacatccatt cgcagtcact gtcttgcaaa ccaggttgaa attggagtgt gtccatgtgc
    13921 agttttggaa tggagtagta gttagataac ttttctgcta tagttgactt accagaacca
    13981 gaatatccga taattgcgat tttcattttc taccttttcc tatttggaga caaaaaaaca
    14041 gcctctatgg actgtttctt atttaacaag tttagctgaa agacgagctt tatcgcggct
    14101 tgctttgttt ttgtgaatca aacctttagt ttctgcttta tcgatagctg agctagcagc
    14161 acggaaaagt tcttcagatg ggtttgcttc gaaagctttt atagcagtac gcatagctga
    14221 tttttgagct gagttctttt cgttttgttt aacgttcaat tcagcgcgtt tgatagctga
    14281 tttaatgttt gccaatgttc ttacctccat atttactaac tataccatta tatatgaaaa
    14341 cttacgtttt gacaagggaa aattactttt ttaagtaaat ttcatcgatt tcatggttct
    14401 tgcttttatg aagaatcact tctgcacgat ttctggttgg ttcaatataa ttttgcagat
    14461 ttgtgagatt gatactgatc cagacctgat gggcaaagga ctccacttcc ccaatcggca
    14521 tctgagtaaa acgataatag tagctatcag ggtcgttttg ggctagactc agcattttca
    14581 agaaacggtc cagataccaa ctttcaatat catccactcc agcatctaca tagatggaaa
    14641 agtcaaagaa gtcagtgata tagagacgat cgttttgtgg attttgaaag acattgattc
    14701 cctcaacaat tacaaaatca gcagctttga cactttgttt ctcttcgggt acgatgtcgt
    14761 aaacttcatg agaatagaca ggaatatcta catcttgtcc atttttgatg cggtccaaga
    14821 agttgagaag agcttccata tcatagcttt caggaaatcc tttacgattt aaaatcccct
    14881 gctcaatcaa ggtttgattg ggatagagaa aaccatcagt tgtaaccaac tcaaccgtag
    14941 catctgtaaa cgtacgggac agtaggattt gaagtaggcg actggttgtg gattttccaa
    15001 cggcaacact cccagaaacc ccaataataa aaggttgaga tttactttca cgttggagga
    15061 aaattccttt tgaaaaggct aaatcttcct tagttcgctt gtaaatctga atcaaatgag
    15121 ccaaggggag atagatatct gtaacgtctt ggagactgat ttggtcatta aaactcttga
    15181 tagattccaa ttcttcttct gtcaaaggag gtgttgtctt tcgatgtaaa gattgccaag
    15241 tctggcggct gattttttca aaatgtaaaa attcgttggt catttgtttt cccctagata
    15301 ttttgtctat cataccataa aaagctaaaa aaataaagcg gtttcttgaa tgtggtaagt
    15361 caatggtata tagtataagt gatcaattta ttgatgaaat aggagataga ttctactgat
    15421 ttataagctt ataaaggggg ctttttagtt cacaacttat aggaggtgta ctatgaaaat
    15481 cttaaaacgt tacatattgg aactctgttt tattttaagt tttgctttac cttttataaa
    15541 aggaaccaat gcagataatg gtagatgctt tgtggaaacc tattacggtt ttactttttt
    15601 gatggaacat gctattgtaa cagctgtctt tatttgttcg ttcttaattg ctttcttact
    15661 aaaaaacgat ggacgaaatg gattgctgcg ggtagttatt gctttttagt cctacggatt
    15721 gcgacagagg gttatttctt ccacatgtca ctagaagatt tgatacgact ttggacaagt
    15781 ttggaaatcc tgacacaaac gtatcagttg ggcttttatc taaacatttt gttaggaatt
    15841 ttgttgataa taaagtattt taaggttaag caatagaaat aataatctgc ctgattatag
    15901 atgataaact ttttgttttt atctggactg tgatatttat agttctaaat ggtttattat
    15961 ttataagtgt tgaaagagat tgaagaaaat ggcttcgtga cttgctttct tcggtctttt
    16021 tcgttttatt atcaatttgt aaacgattta caatttgagt caaattatgg taaaatagtg
    16081 tcatgagtaa aatgtactat gcagaaaatc ctgacgctgc tcacgacatt catgagttga
    16141 gagtggactt gttgggagaa aaaatgactt ttttgacaga tgcgggtgtt tttagcaaga
    16201 aaatggttga ctttggaagt caactcttgc tcaagtgtct ggatgtcaac caaggagaga
    16261 cagtcctaga tgtaggctgt ggttatggtc cattaggttt gtccttggtc aaggtttacg
    16321 gagttcaggc gaccatggtt gatattaaca ctcgtgccct ggatttagct cagagaaatg
    16381 ctgaaaaaaa taatgcaaaa gcgacgatat ttcaatctaa tatttatgca agagttcaag
    16441 ggcgatttga ccatgtcatt tccaatcctc ctatccgtgc gggcaagcaa gtcgttcatg
    16501 aaatcatcga gaaaagtaaa gatttcttgg aaattggtgg agatttgacc atcgtcatcc
    16561 agaaaaaaca aggagctcca agtgccaagt ctaagatgga agatgtgttt ggcaattgtg
    16621 aaatccttaa aaaagacaag ggatactata tccttagaag tgtgaaagaa tgagagcagt
    16681 tgatttaatc caaaaaaaac gagacggtca agaactgact tcaagtgaaa ttgaatggct
    16741 gatagaaggc tatgtatcag gaactgttcc tgattatcag atgtctgcct ttgctatggc
    16801 tgtttatttt aaaggaatga cgactcgaga aatctctgat ttaacgatga atatggttaa
    16861 gactgggcaa gagtttgacc tgtcagccat tgatggtgtg aaagttgaca agcattctac
    16921 tggtggtgtc ggcgataagg taaccttgat tttagctcct cttgttgcta gcttcggtgt
    16981 gcctgtagca aaaatgagtg gtcgtggtct tggccataca ggcggaacaa ttgataaatt
    17041 ggagtccatt aagggctatc aagtagaacg tagtcaagag gattttattc gtcaggttca
    17101 ggatattgga gtatctgtca ttgggcaatc agaccagctg gtcaaagcag ataagcttct
    17161 ctatgccctt cgtgatgtga ccgcaactgt cgacacgatt cctttgattg cgagttcggt
    17221 gatgagcaag aaaattgcgg caggggcgga tgctattttg ctagacgtga ctgtcggtga
    17281 gggtgccttc atgaagacgg ttgatgaggc gcgtgagttg gctcaaacta tggtagatct
    17341 tggtaaggtt gttggacgga agacagtagc agtgattacg gatatgagcc agcctttggg
    17401 acgagcgatt ggaaatcgtc tggaaatcct tgaagcattg gagattttgc aaggtcaagg
    17461 acgtcaggat attacccact ttatttgtga attggctcaa attatgcttg gtttggcaaa
    17521 tgttaacaaa actgttgaag aagttcgcca acatcttgaa aatggtcaag cactggctaa
    17581 gtttgaggaa atggtgcaag cccaaggtgg agacttggaa gacctctatc gtcctgtaaa
    17641 tgtagctcat gtggtggaaa tccctgctca ggaaacgggt gtcatttcag ctcttccagc
    17701 tatggacttt ggtctttatg ccatgaggct gggtgctggt cgtgcagtta agtctgatgc
    17761 cttggactat gaaacaggaa ttgtttttga aaagaagatt ggagactccg ttcaaaaggg
    17821 tgaaattgtt gcaaaagtat acacaaatga aaaaattcca cctcaactag ttacagattt
    17881 ccaaaaatgt gttaaaataa gtgatgaagt gaaaaaaatc cgtgaaattg tagaaatcat
    17941 ctcctaaatg gagggaaaac cgaaatgaaa ttaaataaat atatagatca tacgctttta
    18001 aaacaagatg caaagaaaaa acaaattgat agtttgttgt ctgaggctag agagtatgac
    18061 tttgccagtg tttgcgttaa tccgacctgg gttgaacatg ctaaaaaagg acttgaaggc
    18121 acagatgtta aggtttgcac agtagtaggt ttccctttgg gagcaacaac ttcagccgtg
    18181 aaagcatttg agacaaaaga agctatccaa aatggtgcag atgagattga tatggtgatc
    18241 aatgttggag atctcaaatc aggtaattta gccttggttg agtcagatat tcgcgcagta
    18301 gtggaagcaa gtggtgataa gttagtgaaa gtcattattg aagcttgcct tctgacagac
    18361 caagaaaaaa ttgttgtttg ccaattggcc caaaaagctg gggctgactt tgtcaaaaca
    18421 tctactggct tttcaactgg tggtgctacg atagcagatg ttacattaat gcgtgaaaca
    18481 gttggatctg atatgggagt caaggctgct ggtggagctc gttcttatgc agatgctctt
    18541 gcctttgtcg aagcaggtgc gacccgtatc ggaacgtcag ctggggtagc tattttaaaa
    18601 ggagaattgg cagatggcga ctactgagtt gattgaactg gcaattgaaa ccagcaaaca
    18661 tgcctatgtc ccctattctc actttcctat cggagcagtt ttagtagcca aagacggaaa
    18721 tgtttacacg ggagtgaata tcgaaaatgt tagctatcct ttgaccaatt gcggtgagag
    18781 aacagctatt tttaaggcta tatctgaagg ccaaagagaa ttttcagaat tgattgtcta
    18841 tggtcaaact gaaaaaccga tttcaccatg tggtgcttgt cgccaagtaa tggtcgaatt
    18901 ttttgaacaa gatttaaaag tgaccttagt cgcaaaagat aaatcgacgg tcgagatgac
    18961 ggtcggggag ttacttccat attcttttac agacttaaat tagtctgagt cgctctttga
    19021 gtggcaaggg tctttgtgac caatcaatcc atacttgcaa catcgttgca catcttattt
    19081 aggaggttca gtaatgaaca agaaacaatg gctaggtctt ggcctagttg cagtggcagc
    19141 agttggactt gctgcatgtg gtaaccgctc ttctcgtaac gcagcttcat cttctgatgt
    19201 gaagacaaaa gcagcaatcg tcactgatac tggtggtgtt gatgacaaat cattcaacca
    19261 atcagcttgg gaaggtttgc aggcttgggg taaagaacac aatctttcaa aagataacgg
    19321 tttcacttac ttccaatcaa caagtgaagc tgactacgct aacaacttgc aacaagcggc
    19381 tggaagttac aacctaatct ttggtgttgg ttttgccctt cataatgcag ttgaagaagc
    19441 agctaaagaa cacactgact tgaactatgt cttgattgat gatgtgatta aagaccaaaa
    19501 gaatgttgcg agcgtaactt tcgctgataa tgagtcaggt taccttgcag gtgtggctgc
    19561 agcaaaaaca actaagacaa aacaagttgg ttttgtaggt ggtatcgaat ctgaagttat
    19621 ctctcgtttt gaagcaggat tcaaggctgg tgttgcgtca gtagacccat ctatcaaagt
    19681 ccaagttgac tacgctggtt catttggtga tgcagctaaa ggtaaaacaa ttgcagccgc
    19741 acaatacgca gccggtgcag atattgttta ccaagtagct ggtggtacag gtgcaggtgt
    19801 ctttgcagag gcaaaatctc tcaacgaaag ccgtcctgaa aatgaaaaag tttgggttat
    19861 cggtgttgac cgtgaccaag aagcagaagg taaatacact tctaaagatg gcaaagaatc
    19921 aaactttgtt cttgtatcta ctttgaaaca agttggtaca actgtaaaag atattgctaa
    19981 caaggcagaa aaaggagaat tccctggcgg tcaagtaatc gtttactcat tgaaggataa
    20041 aggggttgac ttggcagtaa caaacctttc agaagaaggt aaaaaagctg tcgaagatgc
    20101 aaaagctaaa atccttgatg gaagcgtaaa agttcctgaa aaataatgga tggaagtcat
    20161 ttcttaggaa gcggccaagg gccgcttttt taagagttga gacaaagtca ttttgtctca
    20221 gtaaagcttg ctactagaca aactagcaag ttttattgaa ataaaataag actctgaaag
    20281 gaagagcaca tggcacacga aaatgtcatt gagatgcgtg atattaccaa ggtgtttggt
    20341 ggatttgttg ccaacgacaa aatcaacttg cacctacgaa aaggtgaaat tcatgcactt
    20401 ttaggagaaa atggggctgg taagtccacg ctaatgaaca tgttagcagg ccttcttgaa
    20461 ccaactagtg gtgaaatcgc ggtcaacggt caagttgtca atctcgactc cccatctaaa
    20521 gcagctagct tgggaatcgg gatggttcac cagcacttta tgttggttga agccttcaca
    20581 gtggctgaaa acatcatttt aggtagtgaa ttgactaaaa atggtgtgct agatatcgct
    20641 ggagctagca aagaaatcaa ggctctttct gaacgttatg gcttagctgt tgacccttct
    20701 gccaaggtag cagatatctc agttggagcc caacaacgtg tagaaatttt aaaaacactt
    20761 tatcgggggg ctgatatcct tatctttgac gaaccaacgg ctgttttgac tccatcagaa
    20821 attgatgagt tgatggctat tatgaaaaat cttgtcaaag aaggaaaatc aattatcttg
    20881 attacccaca aattggatga aattcgcgca gtttctgacc gtgttacagt tatccgtcgt
    20941 gggaaatcaa ttgaaaccgt tgaaattgca ggggctacca atgctgattt ggcggaaatg
    21001 atggtaggac gttctgtttc ctttaaaaca gagaagcaag cctctaaacc aaaagaagtg
    21061 gttttgtcta tcaaagattt ggtggtcaat gaaaaccgtg gtgttccagc tgttaaaaat
    21121 ctgtccttgg atgttcgtgc tggagagatt gttggtattg cggggattga tggaaatggt
    21181 cagtctgaac tgattcaagc cattacaggt cttcgtaagg ttgaatctgg tagcattgag
    21241 ctaaaaggag attcaattgt aggcttgcac ccacgtcaga ttacagaact aagtgttggg
    21301 cacgttccag aagaccgtca ccgtgatggc ttgattttgg aaatgatgat atctgaaaat
    21361 attgcccttc aaacctacta taaagaacca catagtaaaa atggaatttt gaattattca
    21421 aatattactt cttatgctaa aaagctgatg gaagagtttg atgttcgcgc tgccagtgaa
    21481 ttagttcctg cagctgcact ctcaggagga aatcaacaaa aagcaattat tgctcgtgaa
    21541 attgatcgag atcctgatct ccttatcgtt agccagccaa ctcgtgggtt ggatgtcggt
    21601 gccattgagt atatccacaa acgcttgatt gaagagcgtg ataatggcaa ggctgtcctt
    21661 gttgtcagct ttgaattgga tgagatttta aacgtctcag accgtattgc cgttatccac
    21721 gatggtaaga ttcaaggtat tgtatcacca gaaacaacca ataaacaaga acttggtgtc
    21781 ttgatggctg gtggaaactt gggaaaggag aagagtgatg tctaaaaaat tacaacaaat
    21841 ttcggttccc ttgatttctg tatttctagg aattttactc ggagccattg tcatgtggat
    21901 cttcggttat gatgctattt ggggctacga agaattgttc tatacagcct ttggcagtct
    21961 gcgtgggatt ggagaaatct tccgtgctat gggtcctctg gtcttgattg gtcttggttt
    22021 tgcggttgcc agtcgagctg gtttctttaa cgtcggactt cctggtcagg ctttggcagg
    22081 ttggattctc agtggttggt ttgcgctgtc gcatccagat atgccccgtc ccttgatgat
    22141 tctagcaacc atcgtgattg ccttgattgc tggtgggatt gtcggagcga ttccaggtat
    22201 tcttagggcc tatctaggga cgtcagaggt tattgtaacc atcatgatga actacattgt
    22261 cttgtatgta gggaatgcct ttatccatgc tttccctaaa gacttcatgc aaagtacaga
    22321 ttcgaccatt cgtgttgggg ctaatgcaac ctatcagaca ccttggttgg ctgagttgac
    22381 tggtaactca cggatgaata ttggtatttt ctttgccatc attgccgttg cagttatttg
    22441 gttcatgctc aagaaaacaa ctcttggttt tgaaatccgt gcagttggtc ttaatccaca
    22501 tgcttcagaa tatgctggta tttctgccaa gcggactatt atcctatcta tgattatttc
    22561 aggtgccttg gcaggtcttg gtggagctgt tgaaggtttg ggaaccttcc agaacgtcta
    22621 tgttcaaggt tcgtcattag ctatcggatt taacggaatg gcggttagtt tgcttgcggc
    22681 caactcacca attggtatac tctttgcagc cttcctattt ggcgttctcc aagttggggc
    22741 tcctggtatg aatgcggcgc aggtaccatc tgagcttgtc agcattgtaa cagcgtctat
    22801 tatcttcttt gtcagtgttc attaccttat cgaacgcttt gtcaaaccga aaaaacaagt
    22861 taaaggaggt aagtaaagat gtctattata accttgctcc ccctcttggt gtcttctatg
    22921 ctgatttact cagcacctct catctttaca agtatcggtg gtgttttctc tgaacgtggt
    22981 ggtgtggtaa acgttggcct tgaaggaatt atggttatgg gtgccttttc tggagttgtc
    23041 tttaaccttg aatttgcaga acaatttgga gcagcaactc catggctatc cttgcttgta
    23101 gcaggattgg ttggtagtgt tttctctatc atccacgcag cagcgacggt tcatttccgt
    23161 gcagaccatg ttgtcagcgg tacggtattg aacttgatgg cgcctgcctt ggctgttttc
    23221 ttagttaaag ttctttataa caaaggacaa accgacaacc taagtcaaac ttttggacgc
    23281 tttgatttcc cagtcttggc aaatatccca gtgattggtg atatcttctt caagtcaact
    23341 agtctacttg gttatctggc gattgccttc tcattccttg cttggtttat tctctttaag
    23401 actcaatttg gtcttcgtct ccgctctgtc ggtgaacatc ctcaagcagc ggataccttg
    23461 ggaatcaacg tctacaagat gagatattta gggattatta tttcaggttt tctaggtgga
    23521 attggcggag cgatttatgc gcaatcaatc tcagttaact tctcagtgac aactattgtt
    23581 ggacctggat ttatcgccct tgctgcgatg atctttggga aatggaatcc aatcggtgct
    23641 atgctttcta gtctcttctt tggactttca caaagtttgg ctgttatcgg ttctcaattg
    23701 ccgttcctac aaggagtgcc agcggtttat cttcaaattg caccttatgt tttgacaatt
    23761 cttgtcttag cagccttctt tggaaaagca gtcgcaccaa aagcagatgg tatcaactac
    23821 atcaaatcaa aataagcata caaaaaaacg tcagtccaat ga
//
LOCUS       DBERXF010000037        22136 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.37, whole genome shotgun sequence.
ACCESSION   DBERXF010000037 DBERXF010000000
VERSION     DBERXF010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22136
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.37"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            70..981
                     /locus_tag="ACL8JK_001606"
     CDS             70..981
                     /locus_tag="ACL8JK_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS1786462.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            1211..1909
                     /gene="dapD"
                     /locus_tag="ACL8JK_001607"
     CDS             1211..1909
                     /gene="dapD"
                     /locus_tag="ACL8JK_001607"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGS1786463.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            1977..3107
                     /locus_tag="ACL8JK_001608"
     CDS             1977..3107
                     /locus_tag="ACL8JK_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HGS1786464.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            3119..3658
                     /locus_tag="ACL8JK_001609"
     CDS             3119..3658
                     /locus_tag="ACL8JK_001609"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGS1786465.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            3642..4319
                     /locus_tag="ACL8JK_001610"
     CDS             3642..4319
                     /locus_tag="ACL8JK_001610"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGS1786466.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(4391..5290)
                     /gene="galU"
                     /locus_tag="ACL8JK_001611"
     CDS             complement(4391..5290)
                     /gene="galU"
                     /locus_tag="ACL8JK_001611"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGS1786467.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(5312..6328)
                     /locus_tag="ACL8JK_001612"
     CDS             complement(5312..6328)
                     /locus_tag="ACL8JK_001612"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGS1786468.1"
                     /translation="MKKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSIILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHETNIKDTIYDIMNNEFKAE
                     NEWS"
     gene            6540..6980
                     /locus_tag="ACL8JK_001613"
     CDS             6540..6980
                     /locus_tag="ACL8JK_001613"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1786469.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIVQKKESVFAK
                     IFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW"
     gene            complement(7095..7526)
                     /locus_tag="ACL8JK_001614"
                     /pseudo
     CDS             complement(7095..7526)
                     /locus_tag="ACL8JK_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7588..8238)
                     /gene="phoU"
                     /locus_tag="ACL8JK_001615"
     CDS             complement(7588..8238)
                     /gene="phoU"
                     /locus_tag="ACL8JK_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGS1786470.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(8253..9005)
                     /gene="pstB"
                     /locus_tag="ACL8JK_001616"
     CDS             complement(8253..9005)
                     /gene="pstB"
                     /locus_tag="ACL8JK_001616"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS1786471.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(9007..9822)
                     /gene="pstA"
                     /locus_tag="ACL8JK_001617"
     CDS             complement(9007..9822)
                     /gene="pstA"
                     /locus_tag="ACL8JK_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGS1786472.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(9815..10678)
                     /gene="pstC"
                     /locus_tag="ACL8JK_001618"
     CDS             complement(9815..10678)
                     /gene="pstC"
                     /locus_tag="ACL8JK_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGS1786473.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(10796..11671)
                     /locus_tag="ACL8JK_001619"
     CDS             complement(10796..11671)
                     /locus_tag="ACL8JK_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGS1786474.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(11838..13169)
                     /gene="pnpS"
                     /locus_tag="ACL8JK_001620"
     CDS             complement(11838..13169)
                     /gene="pnpS"
                     /locus_tag="ACL8JK_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system histidine kinase PnpS"
                     /protein_id="HGS1786475.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(13170..13877)
                     /locus_tag="ACL8JK_001621"
     CDS             complement(13170..13877)
                     /locus_tag="ACL8JK_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS1786476.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGIEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(13961..14446)
                     /locus_tag="ACL8JK_001622"
     CDS             complement(13961..14446)
                     /locus_tag="ACL8JK_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HGS1786477.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            14432..14989
                     /locus_tag="ACL8JK_001623"
                     /pseudo
     CDS             14432..14989
                     /locus_tag="ACL8JK_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(15304..16995)
                     /gene="argS"
                     /locus_tag="ACL8JK_001624"
     CDS             complement(15304..16995)
                     /gene="argS"
                     /locus_tag="ACL8JK_001624"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGS1786478.1"
                     /translation="MNIKELIASELSSIIDSLDQEAVLKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            17131..17577
                     /gene="argR"
                     /locus_tag="ACL8JK_001625"
     CDS             17131..17577
                     /gene="argR"
                     /locus_tag="ACL8JK_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS1786479.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            17628..20162
                     /gene="mutS"
                     /locus_tag="ACL8JK_001626"
     CDS             17628..20162
                     /gene="mutS"
                     /locus_tag="ACL8JK_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGS1786480.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDCEGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            20309..22003
                     /gene="patA"
                     /locus_tag="ACL8JK_001627"
     CDS             20309..22003
                     /gene="patA"
                     /locus_tag="ACL8JK_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HGS1786481.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELFGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
BASE COUNT         6280 a         4383 c         4838 g         6635 t
ORIGIN      
        1 gataattctc taaatgaagt ggccaatcaa tggattgcca cttttttcct ttcgtgttac
       61 aataagggta tgaatcagta tcagaaaaag attgttaacg gaaaaattta ttcgctccta
      121 tccggcttaa tatggggaat ctgtggaatt ttaggagagt acttctttac tcattatcag
      181 gtgtcttcgg gctggattac ctctatgcgt ttgacactgg cagggagtct tgtactcatt
      241 tggtctgcaa tacaattaaa atcgcaagtg ctagatattt ggcgagacaa gaaaaattac
      301 ctgccctttt tagcttatgc tattttgggg attttttcag tccagtattt tttctatctc
      361 tgtgtagaat actcaaatgc tacgacagca actattttac agtttattag ccctgtcttt
      421 atcctctttt acaatcgctt ggtttatcaa aaacgagcgt caaaaagcgc tgttttctat
      481 gttttggttg ccatgctggg tgtttgcttg atggcgacaa agggagatct ctctcagtta
      541 tccatgacgc cgctagctct tataacaggt ttgctgagtg ccatgggtgt tatgtttaat
      601 gttatcttgc cccaaccttt tgctaagcgt tatggttttg ttcctacggt tgggtggggg
      661 atgattttgg caggtttgtt tagcaatgtc ctctcgccgg tttatcagct ttcctttact
      721 cttgatattt ggagtatctt gatttgcctc attatcgctt tctttggaac ggcttttgct
      781 tttttcattt ccatgaaggc tgtgtccttg gtttctcctt tggtggttgc cgttatcagt
      841 gccagtgaac ctctctcttc tgctctcttg agtgttttgt tcttaggatt agtagtggat
      901 tggtccctcc ttctagctat agccttgatt attttaccca tgatattttt gtctatagaa
      961 gaagcgaaag aaagtagata aaaagtcttt tcttaattct aaaagtgtgc tatactagaa
     1021 tagtcaataa aacacgggga gatagttgtg aagagtgttt ttaggttgta tcggtagggg
     1081 cttgctttta ccgacagcac gttttatctc acatccctaa aaaatcatac ctaaaaacag
     1141 acaaaaaggt ttcaaatttg aggccttttt tggtagaata ggtatcatta taaagaatga
     1201 gaggcctttt atgactgcta caaaaatgaa tgctcaagaa attatccaat ttatcgccaa
     1261 tgctgaaaag aaaaccagtg tcaaagtaac ctttgagggg caactcgcaa ctgctgtgcc
     1321 tagctctgtt gtcaaactag gaaatgtcct attcggagac tggaaggacg tggctccgct
     1381 tcttgaaggt ttggtagaaa atcaagatta tgttgtcgag caagatgctc gtaattctgc
     1441 agttcctttg ctagataagc gtgctatcaa cgctcgtatc gagccaggtg ctattatccg
     1501 tgaccaggtg gaaattggtg acaatgctgt tatcatgatg ggagctgtta tcaatatcgg
     1561 tgctgaaatc ggtgctggaa ccatgattga catgggtgcc atccttggtg gccgtgctat
     1621 cgttggaaaa aatagccacg ttggtgcagg tgcagttttg gcaggtgtga ttgagccagc
     1681 tagtgctgaa ccagtccgtg tcggagacaa tgttcttatc ggtgctaatg cagtggttat
     1741 cgaaggagtc caaatcggta gtggttcagt tgtcgctgca ggagctatcg ttacccaaga
     1801 tgtcccagaa aacgtggtag tagcaggtgt tccagctcgt atcatcaaag aaattgatgc
     1861 ccaaacccaa caaaaaacag cgctagagga tgcgcttcgt accttgtaat tgtaaaagta
     1921 aaaaagaggc ggaacccttt ttccagcctc tttctgctat atcggaggac agatagatgt
     1981 tagatttgat tcagactaga cgagctttac accagattcc agagattggc ttggaggagt
     2041 tcaagactca ggcttatttg ctggatgtga ttgagaaatt gactacgggc aaggattttg
     2101 ttcaaattcg tacttggcgg acagggattt tggtctacct gcagggaagt cagccggagc
     2161 gaaccattgg ttggcggaca gatattgatg gcctgcctat cgtcgaacaa acaggtctac
     2221 cttttgcttc tcaacaccaa ggtcgcatgc atgcctgtgg ccatgatttt catatgacca
     2281 ttgccttagg ctgtcttgag cgcgcccttg aggagcaacc caagaataat ctgctctttc
     2341 tatttcagcc tgctgaagaa aatgaagctg gtggtatgct catgtatgag gatggtgctt
     2401 ttggagattg gttgccaaac caattctatg gtctccatgt tcgtccagat ttgaaagtcg
     2461 gccagattgc gactaatact catacactct ttgcaggaac ttgcgaggtg aagatccgtt
     2521 tcaaaggcaa aggtggccac gcagcttttc ctcatgaagc caatgacgcc ttggtggcgg
     2581 ctagttactt tgtgacccaa gtgcagtcag ttgttagccg caatgtcaac ccaatcgagg
     2641 gagcagtggt gaccttcggc gtttttcaag ctggaaccac caacaatgtc atcacagaca
     2701 cagctttttt acatggaact attcgtgcct tgacacagga catgagtctc ttggtgcaaa
     2761 agagggtaaa aacagttgca gaaggggttg cagctgcctt tgatatggaa gtcgaagtgg
     2821 aactcaaaca aggtggatac ctacctgttg agaacaatcc agccttggcg cgtgaactga
     2881 tggacttctt tgacgaaaaa gacggaatcg agttgattga tatcgaacct gctatgacag
     2941 gcgaggactt tggttatctc ctttcaaagg ttgatggcgt gatgttttgg ctaggtatcg
     3001 atagtcccta cgctcttcat caccctcaaa tgagtcctaa ggaagaagtc ttagctattg
     3061 gggtggctgc ggtgtctagt ttcctgaaaa agaaggcagc agaatagagg gcttgtatat
     3121 gaaatcggaa ttacgcaagc aagtcttgca tgaaatgaag gctttatctc aagaacaaaa
     3181 acaggctata gaccaagctt taaccgagcg aattttacaa cacccctttt atcaagaagc
     3241 caaggtcatc gcaacctacc tctctttttc tcatgagttt caaacgcggg aactgattga
     3301 gcaggcgctg aaggacggca agaaggtttt aatacccaaa acttatccca aggggcgcat
     3361 ggactttgta gtctatgatc cgcagcagtt ggtaaaaact gcctttgcct tactggagcc
     3421 acagggagat ttggaagtgg tggatgtatc tcagattgat ttgattcatg ttcctggcct
     3481 ggcttttacg acggatggat atcggattgg atatggtgga ggttattatg accgctatct
     3541 ggaacatttt tctggtcata ctttgagtac ggttcatcct tgtcaaattc aggactttat
     3601 acctgaaaac catgatattc ctgttcagga ggtattaatt gatgaaggaa atctttgata
     3661 gacgttaccc tgtgacgagt ttcttcctct tagtgacggc cttggtattt ttactaatgt
     3721 tggtcactgc aggcggaaac tttgacaggg cagatacatt atttcgattt ggagccatgt
     3781 atgggccagc tattcgcctc tttcccgagc aggtttggcg tctcttgtct gccatttttg
     3841 ttcatattgg gtgggaacat ttcattgtta atatgctttc actttattat cttggaaggc
     3901 aggtagagga gattttcggc tctaagcagt tcttttttct ctatctctta tcaggaatga
     3961 tgggcaatct ctttgttttt gtatttagtc ctaaatcctt agcagcaggc gcctctacct
     4021 ctctttatgg gctatttgcc gcgattattg ttcttcgcta tgcaactcgc aatccttata
     4081 tccaacagct agggcaatcc tatctgacac tttttgtggt taacattatt ggaagtgttc
     4141 tgattccagg aatcagccta gcaggccata tcggtggtgc agttggtggc gcatttctag
     4201 cagttatctt tccagttaga ggagaaaaac ggatgtataa caccagccag agattaggag
     4261 cggtagtctt gttcgtagga ctcgccattt tgcttttcta caagggaatg ggaatgtgac
     4321 gaagttgaaa gaaaatttgt gtaatgaaaa aagataaggc attttttgaa ccttatcttt
     4381 ttattttatt ttattccttc tcagtcaatt cttttccaag ttggatgagg taattcttca
     4441 aatcatcttt gacttgtggg tgtttgaggg cgtagtcgat ggatgttttc atgaagccaa
     4501 acttgtctcc gacatcgtaa cgagccccat tgaactcacg agcaaataca cgttgtgttt
     4561 tattgagggt gtcgattgca tctgtcagct gaatttcatt tcctgcacct ggagcttggt
     4621 tttcgaggat ttggaaaatt tcaggcgtga ggaggtagcg tccgataata gcaaggtcgc
     4681 taggagcgtc ctctggagct ggtttttcaa caaaggtttc aacactgtaa agaccatctt
     4741 ttccttcgcc ttgcggagca ataaccccgt aagcagatac ttcgtcatga gggactggca
     4801 tgacagcgat agtagacgcg tgggtacgct cgtagtcatc catgagttgt ttggtaagtg
     4861 gaacagcctt ttcgtctgtg atatccatca agtcatcacc aagcataacg acaaaaggtt
     4921 catttccgac gaaagcctta gcttgcaaaa cagcatctcc gagaccgcgt ggatgagttt
     4981 ggcggataaa atgcagacgc atgtcagttg ttttatcaac tagcttcaaa agatctgttt
     5041 tccctttttc tttgaggtta tattccaatt cgaagtttga atcgaagtgg tcctcaatag
     5101 aacgttttga tttaccagtg acaactagaa tatcttcaat acctgatttg agagcctctt
     5161 ccacgataaa ctggatagtt ggtttgtcta cgattggcaa catttctttg gcaagggcct
     5221 tggttgctgg taaaaatcga gttcctagtc cagcagcagg gatgactgcc tttctaactt
     5281 ttgatgtcat aagaatcctt tctatagagg gttaagacca ctcattttct gctttaaatt
     5341 cattgttcat gatgtcataa atggtatctt tgatattggt ttcgtgataa ataacttggt
     5401 aaatggcctg tgtaatgggc atatagactc caagttcttg ggctagttca taggctgctc
     5461 gagtcgttga aattccttcg attaccatgc ccatattagc ttctatatca gctagggatt
     5521 ctcctcgtcc gagagcatct ccagctctcc agttacgaga gtggatggaa gttcccgtta
     5581 cgatcaaatc tcccacacca gataagccgc tataggtcaa tggactggcc ccgagagcca
     5641 cccctaggcg agtaatttca gccaagcctc gagcgatgat ggctgcctta gcattatcac
     5701 caaatccaag accatgtaaa gctccagcac cgacagcaat aatattttta agagcaccag
     5761 cagtttcaac cccgataaca tccgtattgg tataaagtcg gaagtagtga ttactaaata
     5821 gctcctgaac gtattgagct gtttgtaaat ctttagaagc agcagttatt aaagttaggt
     5881 cacgcacaat ggtctcttct gcatgactag gtcctgaaac aacgacgata tcactacgga
     5941 gatgttcagg aatttcttct tcaagaatga ttgataatcg tttatggcta tcaggttcta
     6001 atccctttga tgcgtgcatg atgataacct tatggtccaa ggtttgtgca acttgctggg
     6061 caacaagtcg tgtcactttt gttgggacaa caaacaaaat tgcatccaca tctttcaatg
     6121 tttctgctaa gtcggtgtag gcaatgatat tttcgtctag aacgacatct ttaaagtagt
     6181 gcttattagt atggtgtgta ttaatttcat tgatttgctc gggaagattt ccccaaatac
     6241 gtacctcgtg tccattgtca tttaagactt gtgaaagggc ggttccccaa gaaccaggcc
     6301 ccaagacggc gacagtttgt tttttcatga tttcctcctt gatagggttc tttctcttat
     6361 tctatcatat tctaggggat tttgcacttg cattactggg gtatggtgga aaaatacaca
     6421 aaaaccgaga cgaagggata aactcttagt ctttagttaa aatgagaaga aatctgatag
     6481 atagtttgat tcagtatatg cttataatag aggtaaacaa ctcaggaggt tcttgtaggt
     6541 tgcgagagtt tggcgaaaaa attaaaagat tacgtttggc taaaaaaatc agtcgttcag
     6601 aattttgtgg tgatgagtct gaattaagta tccgtcaatt aattagaatt gaaaatggag
     6661 aatccagacc aacactaaca aagttaaaat atatcgctga acgtttgggg gttgaagatt
     6721 acaagttgat gccaagttat atagagttgg ataaggaata cctagaattg aagtatttct
     6781 tgatgaggac tcctacatac gaagatgaaa ctatcgtcca aaagaaagag agtgtttttg
     6841 ctaagatttt tgaagagtat tatgataggc tacctgagga agaaagattt atcatcccaa
     6901 attattcata tctggcacta acgaactaca cagttcaaaa attaccagaa aagctagttg
     6961 aaatactgtc cttctggtga ttttgcttaa tttctgatgt tcgagacatg attgaggaga
     7021 tttgtcttga ttttttccta aaaaagggca gactcctccc ttggtttgat gctcgatttt
     7081 taaaataagg tgacttattc tgttaggcat gtttccccct gccctctagc tctatatgga
     7141 acagggagta tcagatttat ctggcagatt gtatcaaata aggcttgaaa ctgttttgaa
     7201 taggcgtata gacttgagaa tttgagaata tgtcgtctag cagtagagac atattttccg
     7261 gcaatatgaa ggaagagacg tcgaaaacgc ttgatagtca aggcctttac ttcatcacca
     7321 gctagctgct ttaaaaagag gtagagatta taagccagac agcccatcat catacgtact
     7381 tcattcttaa tcatggtcga actatctgtc ttatccccaa agaatcctgc tttcctttct
     7441 ttgataaagt tttcagcatt ccctcgttca cgatagaatt gaaacagctc ctcactatct
     7501 acactgctta aattgttcaa atgaactttt ttacaaccat aaaaaagagc acttaatcgt
     7561 actcttctct tttaaggatt agttgaatta attcaaatcc actagttctc ctgtttctag
     7621 gtagactagg cgttcacaaa tgttagcaat gtaatcagcg aagcgttcca gatgccctat
     7681 gatataaagg tattgagttc cattgggaat tgaggtttct tggtctttca taagtccaat
     7741 gatttccttt gataaggcat aataatattg gtcaatctgt tcatcttttt gagcaatact
     7801 aatagctttt gaggcttggt gcaaaggaaa ggcaaccaat aaatcggcta gcatgctgag
     7861 ggataattta cccatttggt gtaactgttc ttcgtcaggg gctagttgat tttcttttag
     7921 ttgcaaaaca gctttggcaa tgcctgccat atggtctccc atacgttcaa ggtctgaaca
     7981 agaagacatg atgctaatca caaatcgaag gtcagacact tgtggctgct gcaaggccaa
     8041 caaacgggca caggtcaatt cgatagcgct ttgaccttgg ttgatagcat gatccttatt
     8101 gataattagc tctgccatct ccttgtcttt ggaggctaag gccagtaagg cttttgaagc
     8161 tgtttcaagg acaagttgcc ctagtcctaa aaaggattgt tctaattcat gcaattctaa
     8221 gtcaaattga tttctcatag gtttttcctt ccttatccga accgtcctga aatatagtct
     8281 tctgtgcgct gatcttttgg attggtaaac acgtcaacgg tatctccaaa ttcgcaaatt
     8341 tctcctgtta agaaaaaagc agttttatct gaaatacgtg aagcttgttg catgttatgg
     8401 gtaacaatga taatcgtata atcctttttt agttgctgaa tgaggtcttc aatttttaaa
     8461 gtggagatag ggtctaaggc tgaagtcggc tcatccatta acagaatatc aggttctact
     8521 gctaaagctc gcgcaatgca aaggcgttgc tgctgaccgc cagataagga catggcactc
     8581 tttttaagat catctttgac ttcttcccaa atggctgccc cttttaaaga tttctccact
     8641 aaggcatcta attgtttttt gtctcgaata ccatgtgtcc ttggaccata agccacgtta
     8701 tcatagatag acatggcaaa gggattaggc tgttgaaaaa ccatccctac acgcttgcgt
     8761 agctgattaa ggttgaattt gctactataa atatcttgct catctaagag gacttggcct
     8821 tcaatatggc aagaaggaac caaatcgttc atccgattaa gggtttttag aaaagttgat
     8881 ttgccacaac cagatgggcc tatcaaggca gtaatctgtc tttctggtaa ttgaatcgaa
     8941 atatttttta aggcttgaaa atccccgtaa aataagtcta ggtgtctaac tgaaaatgtt
     9001 cccatactag gaagctcctt tcacaagttt tcgagataat aagcttgata gagtatttat
     9061 cattaaaaca gtaataatca aaatcacacc ggtagcatag gcttcattga catgtagccc
     9121 ctcacttgac agcatataca tatgcagggc tagagaacga cctgaagaca tgagactact
     9181 tggcgtattg gtagaggtac ctaatgtata catgagggca gctgtctcac caacgatacg
     9241 gccaatagct agtatcactc cagctaaaat acctggcatg gcaactggta gaacaattct
     9301 aaaaacagtc cgtaacttac ctgccccaag tccataactt gcttgacgca tgctatcact
     9361 aacagataaa agggcttctt ctgttgagcg aataatgact ggcaacacca tgataactga
     9421 ggttaagatt cctgataaca gagagtattg aaaacctaag aagactacaa agaagagcat
     9481 gccaaacaga ccaaaaacaa tggaaggaat cccagacaag gtatctgagg ccaatcgcat
     9541 gattttaaca caaagggaat ctttttttgt atattccaca agataaaaac cagcaaaaat
     9601 ccctatgggc aaggctaaaa gaagagcacc aaagaccaga ataacggtgg aaataatcgc
     9661 tggcataagg gaaatgttct cagaagtata agtccaagaa aagagggata gacttagatg
     9721 aggtaagcct ttgatgagga taaaaccaat gattaaaaag agagagccaa aggttaaagc
     9781 tgaaaaacaa taaacgagaa gttttagcag gtatttactc ataagatgat tttcctttca
     9841 agtaggcaaa gtaggcatta atcaagagaa taaggaaaaa gagaactgct gaggttgcaa
     9901 taagggcttc cctatgctga cctgatgcgt aagccatttc cagaacaata ttggttgtta
     9961 aggttctggt tcctgaaaag agtccacttg gaataatcgg ctggttgcct gccaccaaaa
    10021 taactgccat ggtttcacct actgcgcgac cgattcctaa aataactgct gataaaatac
    10081 cagatctcgc agctggcaag atgacactaa aaatactccg ttcatgacta gctcctagag
    10141 ccaagctacc agaataatac gttttgggaa ctgttcggat agcagattct gacaaactga
    10201 taatggttgg caaaatcatt attcctaata gtaacgaagc ggttaggaca ctcatgccat
    10261 ttcctaaaaa gcttctaatc caaggcacca ataattgtag gccgaaaaaa ccataaacaa
    10321 tagatggaat ggccgccatc aagttgatag ctgattttaa gaagccatag acgggctttg
    10381 gacaataata aaccataaac accgatgtca agatgcctgt tggcacccca atcacaatcg
    10441 ctcctaaggt aattaataag gaaccaacga tcattggtaa aataccatag cttgccggaa
    10501 tgttcgttgg cgaccaatca ctgcctaata aaaaacgggc aaagccgtag ttagccatga
    10561 aaggtaagcc attactaaaa ataaagaaac agattagcaa aatagctaca acagctactg
    10621 ttgcactcat gaaaaaaatt gccctaaaaa ctgcttcttt gaaggcttgt tttatcacat
    10681 cttgtccttt ctagtgaaga aagtaaggga gatacgacac ctccctactt gccttcttta
    10741 tcttattgta cgatgaaacg tctgcatctc tttagagatt tatggagcaa acattttatt
    10801 taatcttgtc ccaggtggtt aatttgccac taaaaacgtc tgcaagttca gccatactga
    10861 cttggcttgc cttattgtca ttattgacca caacagcaat accgtctaaa gcaatagcat
    10921 catgggtgag actcttacct tcttcaggag ttaattccct agaaaccata ccaatatcag
    10981 cggttttctc cttaacagcg gtaatacctg ctgaagaccc attagaggta atatcaatcg
    11041 taacttctgg attttctttt ttataagctt ctgctaattt ttccattaaa gaagatactg
    11101 aagtggaacc tacaacagac aacttgcctg ataagtgttg gcttgtatat tctgtggttt
    11161 cggttttagc ttcaataaat ttattatctg tgaccacttg ttgaccttgt ttggagtgga
    11221 taaagctgat aaaatcttga cctagcttgg aaagattaga agaccaaaca atgttgaagg
    11281 gacgttgaag agggtattca ccatctaaaa ctgtgtctcg actagccttg acaccatcaa
    11341 tctctaaagc cttgacagat ttcgttaaag atcccaagga gatgtagccg atagcattag
    11401 cattcccttg aactgctgag agaacacctt ctgtactatt ttgaatcaca gctgttttgg
    11461 cagtgttgtc aattttttta tcaccgtctt ttttgagaat ccctgtgatt tctgtgaagg
    11521 caccccgtgt tccagagcca ttttctcgtg aaatcacctc aatcgttcct gaagctgact
    11581 gtttggaagc agctgactga ttgccacagg caacaagccc aaatcctgat aagccaatgg
    11641 ctgcaagagt aagcattttt ttgaatttca taataatcac ctttatctct atgtattttt
    11701 cttgtgtagg cttactacat ttatagtcta acaagtcttt gtaaaggttt atccctgatt
    11761 catgtaaaga ttgtgtaaag aatcaaaaaa agccactttt gaaaaatggc tgctcctaaa
    11821 aatagcttta aaaattatta gtcctgtgcg aaagattggt taggaagaaa aatcgtgaag
    11881 caactgcctc tgccaagctg actcgtcacc gtgacttggc cacctaataa ttgactgagt
    11941 tctttgacaa tggcaaggcc aagaccagtg ccaccagttt gtctgcttcg acctttatta
    12001 actcggtaaa aacgttcaaa aatacgatcc tgctctaatt gactaatacc aatccctgta
    12061 tctgatacag aaatcttaat gccttcgttc accttttggg tcttgacctc aattttcccc
    12121 ccttgttcag tgtaacggat ggcattggat aaaagattga gtaagatttg ggaaagtaat
    12181 tgactatctg atacgagggt gacatcatct ggcacctgca cctttagctg taaatccttc
    12241 ttcttgagct gaggttgcaa gctttgagtc aaatcctgta caaattctgc caaagaaagg
    12301 gtcgtccatt gtataggcat ttgttgagcc ttagataagg taagaagatg ctcaacaata
    12361 tgctcaagac gcaaactttc tttgtaaata atgtctagaa agtcatcctt gagcgcttct
    12421 tcttcagctg acatcccctt aatggtttca gcaaagccct taatcgaagt aactggtgtc
    12481 ctcaattcat gggaggcatt tgagacaaag gctaaattta acttttcata agttctaatc
    12541 gttgttaaat catatagcaa gacgagcaca gcttccacag attgggtggg gctaaaaacg
    12601 ggaactgctg tcacttctaa aatcaagtca ccctcatgaa acccacttac ttcttgtttt
    12661 aaccttgttt tttgatcaaa ggcttggtga actaaattcc gaatatccat ccgtttgagg
    12721 tcatcaagtg aacttatgtc gccgtccaca tcgggaaaat aatgaggcag agagcgactg
    12781 gataataaca tctgaccttg agcggaaact aaaaacgtcc ccatggttag gtgcgacaga
    12841 agaacctcca ttgtttcggc tagatccttg tattgctgat cctgttggga gactttggtt
    12901 tttaggccag acacatactg agccaaagac tttaagtctt cttgcccttt ttctaaaaag
    12961 tattcactac tggtcaagag aggttggtgc aaggtctcaa aagcaacttc ccatttccaa
    13021 aggcaaaaga gccagtagcc acctagtccc aaagaaaggg ctagaagaaa gagaccgatg
    13081 cctttactga tccaagttaa tgccatccct gcaatcagaa tgaggctaac acttagattg
    13141 actagccaaa attgaaggta gcgtttcatc tataactcct tgaacttata accataaccc
    13201 cgaatggttc gaataaattg aggggcttta ggattgtctt caattttttc cctcaactta
    13261 ccaatatgaa cgtccaccaa acgtgtttcc tgcccaaagt cataccccca gatacgttcc
    13321 aaaagacgct ctctagtcag tgtcatgttg ggatgtttca taagatagag caagagttca
    13381 aattcttttg gggtcaaact cagtaactta ttcgccttgt agacttcatg acgctcaggg
    13441 tatactttca aggtcccaaa tagccaagaa tcgtcagcga tattatctga atcatctcct
    13501 tcttgttctc ctttagttcg cctgaggaca gccttgacac gcgccagcaa ttctctaggg
    13561 ctaaaaggct tggtcaggta gtcatcagcc cctaattcca aggccaaaac cttatcaaat
    13621 tcatcacttt tcgcagaaac catcataatt ggagttttga cgcctttggc tctcagccgc
    13681 ttacaaactt ctatgccatc taattgtggt aacatgatat caagcaagat aaaatcaaag
    13741 ggttctgttt ctgccaaagc taaggccttc cgtccatttg tcaccaattg agtagaaaag
    13801 ccttccttac ttaaatggta gtcaagcaat ttcagaatgt gttcttcatc atccactaat
    13861 aagacttgtt ttgtcatcta ttatctccta ttggtaacat tataacacaa ttatcagaaa
    13921 tcctaacatt gctaaatcag attaaatttg cctatcaaga ctagtatctg gtcaaacgct
    13981 caatcatctc cttgtgctct ggataggtcg ccagtagatc taccctttca aataattcaa
    14041 aatcctcaaa ttcaaaacca ggagcaacaa gacaagaaac cagagcataa tccttatcaa
    14101 ctgttgatcc ccaaatagtg cccttaggaa cacagtagtg aagttgttgc cctttggata
    14161 tgtccaggcc taaagtgact gcttcgtagt gaccatctgc tgtaatcatg tgaacagtaa
    14221 gtggggatcc tgcatgaaaa taccagattt catctgctgt caatcggtga aaatgtgaag
    14281 gattcgtttc ttctaataag aaataaatac tggtataaag cgcccttccc ttaccagcaa
    14341 ggtttatagt gtctgaagct ttttttgttt gtctaaaata gccaccttca acatggggag
    14401 ctaactctag agttcttatc aagtcttctt tatccgtcgg agccaatggg ttgaagtaac
    14461 tcttgttcaa agtggtttta cgatttcaag aactcctctc agttctgagg acacggtaat
    14521 gattgatgcg acggaagtac aaatcaatcg ccctaaaaaa agaattagcg aattattctg
    14581 gtaaaaaaaa tgccacgcta tgaaggctca agcgattgtc acaagtcaag ggagaattgt
    14641 ttctttggat atcgctgtga actattgtca tgatatgaag ttgttcaaaa tgagtcgcag
    14701 aaatatcgga caagctggta aaatcttggc tgacagtggt tatcaagggc tcatgaagat
    14761 atatcctcaa gcacaaactc cacgtaaatc cagcaaactc aagccactaa cagttgaaga
    14821 taaagcctat aaccatgcgc tatccaagga gagaagcaag gttgagaaca tctttgccaa
    14881 agtaaaaacg tttaaaatga tttcaacaac ctatcgaaat catcgtaaac acttcggatt
    14941 acgaatgaat ttgattgctg gcattatcaa tcatgaacta ggattctagt tttgcaggaa
    15001 gtctattatt tggttaggtg aattagtgaa gcgtttaggc aagtgtctct ggttacgacg
    15061 tcatggactc taaatcgatt atatttaggg gtcatgacta gtgaagcagt tagctagttc
    15121 gcatataagc ggctagcgtc taacaattag gaactttagt tccaataact ttaagattac
    15181 gacgttttag gacataaatc gatcatattt atgtcctaaa actagtgaag cgcctagcca
    15241 aagtccgaat aggatttggc gttagttact tagattgctt tgcaatcaag taactttggc
    15301 gatttacatc ttctctggcg cttctactcc aagcaagcga agggcttctt tgagaacgac
    15361 tgcggttgcg tagctgaggg ctagacggct gtcgcgttct gggctttcat ccaagatacg
    15421 tgtatgtgca tagtatttgt taaaggattg agccaggcta attgcaaatt tagcaatgat
    15481 agaaggttca aagttatctg ccgcacggtt gataatacgt gggaagtctt gaatgagttt
    15541 aatgatttcc cagctttcag tatcattcaa gctatagttg ccagctgttt ctggtttgaa
    15601 atcggctttg cgtaagatag attggatacg agcgtaggca tattgaacgt aaggtccagt
    15661 ttcaccctcg aaggatacca tagcctctag gtcgaagtcg tatccatttg tacggtcggt
    15721 tttgaggtca tagaatttaa tggctccaac cccaacagca tgtgctactt ggtctttgtt
    15781 ttctagttca ggatttttag cctcgatttg gaccttggca cggctaacag cctctgcaac
    15841 agtaggctct agcaagatga cattcccttt acgagtagag agcttcttcc cttcttttgt
    15901 aaccagacca aaaggaacgt gggtaatgtc gtcactccaa tcgtagccca tctcttgcaa
    15961 gacagctttg agttgtttaa agtgggcaga ttgctcttga ccaacgacgt agatagattt
    16021 agcaaattgg tattcatttt tacggtagag ggctgcagcc aagtcacgtg tgatatagag
    16081 agttgcacca tcagacttct tgatgagagc tggatgttca attccatatt tctcaagatt
    16141 cacaacttgg gcaccttctg attcaagaag tagtcctttt tcagaaagaa tgtctacaac
    16201 tgcatccatc ttatcattgt agaaggcttc tccgttatag ctgtcaaatt caaccttcaa
    16261 ttcattgtaa aggcggttaa attccactaa actttcatcg cggaaccatt gccaaagagc
    16321 gagagcttcc tcatctccat tttcaagttt acggaaccat tcgcgcgctt cttcatccaa
    16381 gctagggtca ttttcagctt cagcgttgat gcggacatag agtttaagga gttcatcgat
    16441 tggatgagct tttacagctt cttcgtcgcc ccatttttta taggcaacaa tcaacatccc
    16501 aaattgttta ccccagtctc ccaaatggtt gaccttgacc gtttgataac cgattttttg
    16561 gaaaatatgt gacaagctat ctccgataac agttgaacgc aggtggccaa tagaaaatgg
    16621 tttagcgata ttcggactag acatgtcgat aacaacattt tcttgtttac caatattttg
    16681 gtcagcatag tgttcttttt cagtggtaac agcttgcaat acttgagcag aaatggcaga
    16741 tttatcaagg aaaaagttaa cgtaaggtcc tgttgcgaca actttttcaa aggcttggct
    16801 gttcattttt tcagccagtt cagccgcaat catttgtggt gctttacgtt cgacttttgc
    16861 aagagaaaaa gcagggaaag caatgtctcc catttctgag tttttagggg tttccagtaa
    16921 ctttaaaaca gcctcttggt ccaggctatc aatgatgcta gataattcgc tagcaatcaa
    16981 ttcttttata ttcattaaga gctccttttt ggacttttct actattttat cacaatttta
    17041 aagaaagaag aaaaaatttt tgaaatctcc tgtttttttg gtataatatg gttataaata
    17101 tagttataaa tatgcacgca agaggatttt atgagaaaaa gagatcgtca tcagttaata
    17161 aaaaaaatga ttactgagga gaaattaagt acacaaaaag aaattcaaga tcggttggag
    17221 gcgcacaatg tttgtgtgac gcagacaacc ttgtctcgtg atttgcgcga aatcggcttg
    17281 accaaggtca agaaaaatga tatggtgtat tatgtactag taaatgagac agaaaagatt
    17341 gatttggtgg aatttttgtc tcatcattta gaaggtgttg caagagcaga gtttaccttg
    17401 gtgcttcata ccaaattggg agaagcctct gttttggcaa atattgtaga tgtaaacaag
    17461 gatgaatgga ttttaggaac agttgctggt gccaatacct tattggttat ttgtcgagat
    17521 cagcacgttg ccaaactcat ggaagatcgt ttgctagatt tgatgaaaga taagtaaggt
    17581 cttgggagtt gctctcaaga cttatttttg aaaaggagag acagaaaatg gcgatagaaa
    17641 agctatcacc cggcatgcaa cagtatgtgg atattaaaaa gcaatatcca gatgcttttt
    17701 tgctctttcg gatgggtgat ttttatgaat tattttatga ggatgcggtc aatgctgcgc
    17761 agattctgga aatttcctta acgagtcgca acaagaatgc cgacaatccg atccctatgg
    17821 cgggtgttcc ctatcattct gcccaacagt atatcgatgt cttgattgag cagggttata
    17881 aggtggctat cgcagagcag atggaagatc ctaaacaagc agttggggtt gttaaacgag
    17941 aggttgttca ggtcattacg ccagggacag tggtcgatag cagtaagccg gacagtcaga
    18001 ataatttttt ggtttccata gactgcgaag gcaatcaatt tggcctagct tatatggatt
    18061 tggtgacggg tgacttttat gtgacaggtc ttttggattt cacgctggtt tgtggggaaa
    18121 tccgtaacct caaggctcga gaagtggtgt tgggttatga cttgtctgag gaagaagaac
    18181 aaatcctcag ccgccagatg aatctggtac tctcttatga aaaagaaagc tttgaagacc
    18241 ttcatttatt ggatttgcga ttggcaacgg tggagcaaac ggcatctagt aagctgctcc
    18301 agtatgttca tcggactcag atgagggaat tgaaccacct caaacctgtt atccgctacg
    18361 aaattaagga tttcttgcag atggattatg cgaccaaggc tagtctggat ttggttgaga
    18421 atgctcgctc aggtaagaaa caaggcagtc ttttctggct tttggatgaa accaaaacgg
    18481 ctatggggat gcgtctcttg cgttcttgga ttcatcgccc cttgattgat aaggaacgaa
    18541 tcgtccaacg tcaagaagta gtgcaggtct ttctcgacca tttctttgag cgtagtgact
    18601 tgacagacag tctcaagggt gtttatgaca ttgagcgctt ggctagtcgt gtttcttttg
    18661 gcaaaaccaa tccaaaggat ctcttgcagt tggcgactac cttgtctagt gtgccacgga
    18721 ttcgtgcgat tttagaaggg atggagcaac ctactctagc ctatctcatc gcacaactgg
    18781 atgcaatccc tgagttggag agtttgatta gcgcagcgat tgctcctgaa gctcctcatg
    18841 tgattacaga tgggggaatt atccggactg gatttgatga gactttagac aagtatcgtt
    18901 gcgttctcag agaagggact agctggattg ctgagattga ggctaaggag cgagaaaact
    18961 ctggtatcag cacgctcaag attgactaca ataaaaagga tggctactat tttcatgtga
    19021 ccaattcgca actaggaaat gtgccagccc actttttccg caaggcgacg ctgaaaaact
    19081 cagaacgctt tggaaccgaa gaattagccc gtatcgaggg agatatgctt gaggcgcgtg
    19141 agaagtcagc caacctcgaa tacgaaatat ttatgcgcat tcgtgaagag gtcggcaagt
    19201 acatccagcg tttacaagct ctagcccaag gaattgcgac ggttgatgtc ttacagagtc
    19261 tggcggttgt ggctgaaacc cagcatttga ttcgacctga gtttggtgac gattcacaaa
    19321 ttgatatccg gaaagggcgc catgctgtcg ttgaaaaggt tatgggggct cagacctata
    19381 ttccaaatac gattcagatg gcagaagata ccagtattca actggttaca gggccaaaca
    19441 tgagtgggaa gtctacctat atgcgtcagt tagccatgac ggcggttatg gcccagctgg
    19501 gttcctatgt tcctgctgaa agcgcccatt taccgatttt tgatgcgatt tttacccgta
    19561 tcggagcagc agatgacttg gtttcgggtc agtcaacctt tatggtggag atgatggagg
    19621 ccaataatgc catttcgcat gcgaccaaga actctctcat tctctttgat gaattgggac
    19681 gtggaactgc aacttatgac gggatggctc ttgctcagtc catcatcgaa tatatccatg
    19741 agcacatcgg agctaagacc ctctttgcga cccactacca tgagttgact agtctggagt
    19801 ctagtttaca acacttggtc aatgtccacg tggcaacttt ggagcaggat gggcaggtca
    19861 ccttccttca caagattgaa ccgggaccag ctgataaatc ctacggtatc catgttgcca
    19921 agattgctgg cttgccagca gaccttttag caagggcgga taagattttg actcagctag
    19981 agaatcaagg aacagagagt cctcctccca tgagacaaac tagtgctgtc actgaacaga
    20041 tttcactctt tgatagggca gaagagcatc ctatcctagc agaattagct aaactggatg
    20101 tgtataatat gacacctatg caggttatga atgtcttagt agagttaaaa cagaaactat
    20161 aaaaccaaga ctcactagtt aatctagctg tatcaaggag acttctttga caattctcca
    20221 cttttttgct agaataacat cacacaaaca gaatgaaaag gagctgacgc attgtcgctc
    20281 ccttttgtct attttttaag gagaaagtat gctgattcag aaaataaaaa cctacaagtg
    20341 gcaggccttg gcttcgctcc tgatgacagg cttgatggtt gctagttcac ttctgcaacc
    20401 gcgttatctg caggaagtat tagacgccct ccttactggg aaatatgaag ctatttatag
    20461 tatcggggct tggttgattg gtgtggccgt agtcggtcta gttgctggtg gactcaatgt
    20521 tgtcctcgca gcctatattg cccaaggagt ttcatccgac cttcgggagg atgccttccg
    20581 taaaattcaa accttttctt atgctgatat tgaacaattt aatgcgggaa atctagtcgt
    20641 tcgaatgaca aatgatatca accagattca gaacgttgtc atgatgacct tccaaattct
    20701 tttcagactt cccctcttgt tcatcggttc gtttatccta gcggttcaaa ccttaccttc
    20761 tctgtggtgg gtgattgttc tcatggtagt cttgattttt ggtttgactg ctgtcatgat
    20821 gggaatgatg gggcctcgtt ttgccaagtt tcaaaccctt cttgagcgca tcaatgccat
    20881 tgccaaggaa aatttacgtg gcgttcgtgt ggtcaagtcc tttgtccaag aaaaagagca
    20941 atttgctaag tttacagagg tctcagacga gctttttggt caaaaccttt acattggtta
    21001 tgccttttca gtagtggaac cctttatgat gttggttggt tacggggcgg tcttcctctc
    21061 tatttggctg gtcgcgggaa tggttcagtc ggatccgtct gttgttggtt ccatcgcttc
    21121 ttttgttaat tacctaagcc agattatctt taccattgtt atggttggat ttttgggaaa
    21181 ttctgtcagc cgtgccatga tttccatgcg tcgtattcga gaaattcttg acgcagagcc
    21241 agctatgacc ttcaaggata tcccagatga agagttggtt ggaagcctta gctttgaaaa
    21301 tgtgaccttt acctatccaa tggacaagga accgatgctg aaagatgtga gctttactat
    21361 tgaacctggt caaatggttg gtgtagttgg agcgactggt gcaggaaagt caaccttggc
    21421 tcaattgatt ccacgtctct ttgatccaca gaacggggcc attaaaatcg gtggcaagga
    21481 tattcgagaa gtgagtgaag gaaccctgcg taaaacagtt tccatcgttc tccaacgtgc
    21541 cattcttttt agtggaacga ttgcagataa cttgagacag gggaagggaa atgctactct
    21601 atttgaaatg gagcgcgcag ccaatattgc ccaggctagt gaattcattc atcgtatgga
    21661 gaaaaccttt gaaagtccag ttgaagaacg gggaaccaat ttctctggtg gacaaaaaca
    21721 aaggatgtcg attgcgcgtg ggattgtcag caatccacgt attctgattt ttgacgattc
    21781 gacctcagcc ttggatgcca aatcagagcg cttggtgcaa gaagctttga ataaggactt
    21841 gaaggggacg acaaccatta ttattgctca aaaaattagc tcggttgtcc atgcagacaa
    21901 gatcttggtt ctaaatcaag gacgattgat tggtcaaggc acgcatgcag acttggttgc
    21961 caacaatgcc gtttaccgtg aaatctatga aacacagaaa tgaaagacaa actataagaa
    22021 aagtcaatag ttttatctaa attatttctt atttcaattt gatgatttgg cgatgatttt
    22081 agagcacggc aaaaagccct tgaaaaagtc cattttttca aaggtaatcc tgtgtt
//
LOCUS       DBERXF010000038        21320 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.38, whole genome shotgun sequence.
ACCESSION   DBERXF010000038 DBERXF010000000
VERSION     DBERXF010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21320
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.38"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..1879)
                     /locus_tag="ACL8JK_001628"
     CDS             complement(<1..1879)
                     /locus_tag="ACL8JK_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HGS1786482.1"
                     /translation="MVRFTGLSSKQAQAIEVLKNHISLPDVEVAVTQSDQASISIKGE
                     GGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(1873..2742)
                     /locus_tag="ACL8JK_001629"
     CDS             complement(1873..2742)
                     /locus_tag="ACL8JK_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGS1786483.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILNKTSIPTPESLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQIPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGQTDWDGRKIYQEAAAGNAICQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEENQW"
     gene            complement(2826..5471)
                     /locus_tag="ACL8JK_001630"
     CDS             complement(2826..5471)
                     /locus_tag="ACL8JK_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGS1786484.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTILVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTELIKKEEI"
     gene            complement(5562..6842)
                     /locus_tag="ACL8JK_001631"
     CDS             complement(5562..6842)
                     /locus_tag="ACL8JK_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGS1786485.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7013..9097
                     /locus_tag="ACL8JK_001632"
     CDS             7013..9097
                     /locus_tag="ACL8JK_001632"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGS1786486.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QGGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEGGDWRIDLASSQTEMQLATSFIS
                     PSQALLNLPQEDFDSCKSSAQADWENLLHRFDIIEIGEADRTFFDHCLYRLFLFPQTF
                     YEINESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIANCAKKLKNIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(9137..10816)
                     /locus_tag="ACL8JK_001633"
     CDS             complement(9137..10816)
                     /locus_tag="ACL8JK_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HGS1786487.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQYGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSMPLLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            11572..12801
                     /gene="arcA"
                     /locus_tag="ACL8JK_001634"
     CDS             11572..12801
                     /gene="arcA"
                     /locus_tag="ACL8JK_001634"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGS1786488.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            12859..13875
                     /gene="argF"
                     /locus_tag="ACL8JK_001635"
     CDS             12859..13875
                     /gene="argF"
                     /locus_tag="ACL8JK_001635"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGS1786489.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14040..14987
                     /gene="arcC"
                     /locus_tag="ACL8JK_001636"
     CDS             14040..14987
                     /gene="arcC"
                     /locus_tag="ACL8JK_001636"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGS1786490.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            15198..16709
                     /locus_tag="ACL8JK_001637"
     CDS             15198..16709
                     /locus_tag="ACL8JK_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGS1786491.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            16731..18062
                     /locus_tag="ACL8JK_001638"
     CDS             16731..18062
                     /locus_tag="ACL8JK_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HGS1786492.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            18157..19508
                     /locus_tag="ACL8JK_001639"
     CDS             join(18157..18598,18598..19508)
                     /locus_tag="ACL8JK_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGS1786493.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKEIQASMSRKGNSPDNGMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSFG
                     "
     gene            complement(19743..20351)
                     /locus_tag="ACL8JK_001640"
     CDS             complement(19743..20351)
                     /locus_tag="ACL8JK_001640"
                     /inference="COORDINATES: protein motif:HMM:NF016726.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HGS1786494.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            20529..21287
                     /locus_tag="ACL8JK_001641"
     CDS             20529..21287
                     /locus_tag="ACL8JK_001641"
                     /inference="COORDINATES: protein motif:HMM:NF013539.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGS1786495.1"
                     /translation="MADYILVRDSEIVYETSSEIVSKVKVGEGTLNRFCKKIGYSGFQ
                     ELKLKMTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIELAIKLIREAN
                     QILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDLIIAFSLSGS
                     TKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGGSLMAKASQL
                     FIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
BASE COUNT         6278 a         4541 c         4355 g         6146 t
ORIGIN      
        1 aagtcgtata aatcgtcgaa gctgtcgcaa tggtatgcca ctggttagct gtagttgctg
       61 cgaaatcctt gtctgcgtag aagtcagtaa atggtaggat ttcaacttcc agctcgtcga
      121 tgcggtcaag ctggccagcc agataaacct cgatacggct ttctgctcgt ttgatgcgtt
      181 gcaagagtcc gcccatacgg atgtcaactg tatccaaacc aaagaccttg ttttctttca
      241 gccattggtg gctaaagagg gcatggaagt cttcaatttg gcttctaagt tctggtaatt
      301 cttgtctggc gatttgttgt aaactttctt tatcatccgc ttggtaggcc tgacgaatgc
      361 gtcgtcccac atctactttg ctacttaaaa tagcattcaa ctgggcctga gtttcaaaga
      421 gataagcata gtttccagct ttttctttaa tgttagcaag cgtctcagca gcctgagcga
      481 agtgcggttt gtcctgttca ggtgtcatgt gttgatcaag aatcggacaa agaatatcct
      541 gataaaaaac atagcggttg ggattgatac cgctgagatt gcctggtagg tctggtaaga
      601 ggttggcaag gtcaatctgc ataaaatcct caaccgttag accagtattg gtcttgaagt
      661 gcgcagacaa accatctagg tcattgcgat agctgagttc tgcccagatt tgcaagcttg
      721 gtaggataga gaactgggca gtttcaccac cattgtctcc ccaaccagtt acgatgactt
      781 ctttaatctg attggcacgg caggctttat tagcctcgat agccactaga cggctaaaat
      841 gattgtgagg tgtaaagcca atccacttcc aagctccccc tgcaaatgca aggtcatggc
      901 taatcttgtg atgattgcgg aaattacggt tgtatttttc ctcgctatcc tgataataat
      961 cccagtaaac cagagtcaca cggtctttga gacggtctag gtagacacga gtttcctctg
     1021 gaatttccac atcacggtcg tactggccat ccgctgacat gagtttgaag aacatatcac
     1081 tccacatctg gcagtggaaa ccatatttgt cagcaatatc cagcacgcgc tccaagtgtt
     1141 ggcacatgag gagactacga tccacaacac cgttcagaat caggtagcgt cccaaaccaa
     1201 ccaagtgggc ttcgtccatc ccgatattga ccttgcgagt cttcagttta gacaacgtgg
     1261 caaacatgcc atcaatcagg tcataaacct tttcttcgcc aatgagaaga atgtcctcta
     1321 catcacggag ctcctgcact tccttgacac cccatttgac aaaggctgac aggtgggcca
     1381 aggtctggat gcatggtaca aaggtcatgt caaactgttg agcataggct tcgatttcct
     1441 gcaactcctc tgctgaataa gctccacgga aatagccaaa gtaaggctgc ccttcaatct
     1501 ggtaagtgtc ttccatgtaa agctcaaagg ttgagtagcc catgagagcc aagacctcaa
     1561 tcatctgctt ggcagaagcc acattcagca ccgcatttcg agaacagtca accatgtaag
     1621 ccaaatcttc gtaagctgct tgttcctcaa tctctacttt atcagcttct gctagaactg
     1681 ttaccaacaa ggacaaggca cgataaagtt ggtgaggttt gcgataggtc aattgatagt
     1741 ggccaccctc acccttgata gagatagagg cttggtcaga ctgagtaaca gccacttcaa
     1801 catctggcag agaaatgtga ttttttaata cttcaatagc ttgcgcttgt ttggaactaa
     1861 gtcctgtaaa tcttaccatt ggttttcctc ctgtagccag ttgacaaggg caccgtagag
     1921 attagcatct gcatgatagg tgcaggcttg gataacgggt gcgaccgtat attcttcgta
     1981 agtatcgaca aagtcttcaa cagccttctt gacaccttga ataaaatctg gattttgact
     2041 gatagagcct cccagactga tgacatctgg atcaatcaga tactggatat tgagcaagcc
     2101 ttgcgccaaa ttgcggttca tgcgctcaat ggcttcttgg caaatggcat tcccagctgc
     2161 agcttcttgg taaatcttgc gaccgtccca atcagtctga ccagattttt caatcacgta
     2221 gcgaaccata ttcccagttg acgctagttg cgaccagttg ttgagctttt cagcaggggc
     2281 aagggttgtc atatagccaa attctccacc caagccgtgg cgacctcggt gcagtctgcc
     2341 attgataatc atagctccac caatccctgt cccaatcacg acacaggctg cattttcaag
     2401 ttctggatga gccagtaatt cactgagtcc aacgcagttg gcatcatttt ccagatggac
     2461 aggaatctga taagagctaa gcgcctcata ccaagaaaag ccatggatgt agggcaccgc
     2521 actgaagcca tcaatcacac ctgtctcttg attgaccgca cctggaacac tcatagcaat
     2581 cccactgtaa tcctgctctg acaagcgctg gtctagccaa gctagtaaat cctccaagct
     2641 ttcaggcgtt ggaatgcttg tcttattcag tatttttcca tcaggagtca gactggcaaa
     2701 cttaattcca gtccctccga tatcaatcgt tgcaatggtc attgttttta ccataaaaag
     2761 gggcgaatca gcagttagtt cttactcttt cgcccctcct ttctctttat gtttactttt
     2821 tgaaattaga tttcttcttt tttaatcaat tctgtacgaa tttcttgtgg agccaatagt
     2881 cctgaatgaa ctggatatgg tcgctcaagt aagtcaagaa tggtttgttg atgttctgat
     2941 atgcgcacat tttcttgact catattatag taacggagga catagccttc ttcattttcc
     3001 gccactttaa aggctgttgg acaaacttgc ggtatgctga gaacagaatg gctcaagagg
     3061 ctaccagtcg caaccacgct tccttcctgt ctagcaagct gaaggctggt aaacggtgtc
     3121 tgcaaggctt tggcacgacg ataggctgag aagcgttctt gggcttggtg gcattcaatc
     3181 gcaaattcga cttcaaactc ccgcaagcat tgtgcttctg gcgttgggaa gtagccccag
     3241 tcacctagct cacctgatgc acgcaaaatg gtcacggcaa tggtgttatc cccaaggatt
     3301 tcgtattcat tcaatccctt attggataca gtcacccctt tttcatcgtc atacagactg
     3361 acaaaagctt gttggtgttg aggattttca ggattttccc atgaagcagc tggtttgttt
     3421 ggtcgtgtca ccacctcata gatactttca gaatcattgc ttggacgcgt gttatgagtc
     3481 ttgaccaaga gacggatacg gtgatccttg gcagtgttag taaagcgagt cttgaagcgg
     3541 atttgtggat tgtcaacgaa gacagtcaac tcagtttcca gaggaatgtt tgtcaattct
     3601 tctgaccgtc cagcctcacg cttcataaac tcgatgatac cttgttgctc ttcttctagc
     3661 ttttcatccg cactgacagg cacggtcaat tcatgtttga gcaagatttt agcatagcga
     3721 tctgtgtttt ccaagacctc gtggccctta agctctgcaa agattggctc tgttcctttt
     3781 ggttggaaat agatatactc gtttccgatg tcaccccggt cttcaaagcg gataaagtct
     3841 tcataggctt cgtgagttgt cttgtcatag actgtgatgt tgtcatccac actcaccgtt
     3901 acgaatggtg tatcaatcac tccgttttgg taaataccct cacggtgttc ttgttttcct
     3961 tccagcaatt ggaaggttgt ccaagaaagc ggtgctaggt gaactagaat ggtcacacgc
     4021 acttgtcgag caatacgagc ttggcggaac ttatcttttg gtaaatcgta ttcaaaatta
     4081 gctccgaggt cttcgattgt agcctctaca ggacgaccat ccaagtcctc cacacggtaa
     4141 cttggcaaga taagagcagc catctttttg tagccttctg ttgggtgcaa ttccttgaaa
     4201 tcacaagtcg ccacatcaat cactgtgctg acagtatcga ccttatcatg caagcctgtg
     4261 ttaatgacag taaagagata gtcactttga gccttatccg tagcaatttt acccttccac
     4321 tcgttgagca aattactttt aacaaagttt cctacttggt tgaccttggc aaaacgcgtt
     4381 tccatctcgc ggtgaacttc gtccacgcta cagccacaga tactatcatg tggcgcattc
     4441 tgcaaaagtg ttttccaagc ataggtcaac tggtccttgt ggttgtgtcc accagtgata
     4501 atagtcaagg gttctaccac ttgctctagg aggttgctat tttcttggaa ggcttgtttt
     4561 aggtaaatac gggatgaaga agtgttggca agtgtgtacc agccatctgt ttcctgactg
     4621 gtcaactcgc ctgtaacagt tgataagtgt tcaggaagcg caccttctac agcttgaaca
     4681 tattcatcaa aagaactatg aacaaagatt acatccggga agagttcatt tgccacacga
     4741 atggcttcgc tcagattttt ctgtacaggc tggtggtcac agccgttcat catcaaccat
     4801 tggttggtcg aagcgtaggc acgcacatct gacaattttt gtttccagaa ggtcaaggcc
     4861 tcatctttgt caactggaat ttcattcccg ttactgtacc agttggcaaa gagaatacct
     4921 aaaacacgac taccatccac accctgccag tacatttctg aaaactggga tgtaaactgc
     4981 tcatcttcaa ggacttggtt gtcaaatcca atcggcttca caccacgacc aaaggccgcc
     5041 acgtgaatgc ctgatttttg aagaatttga ggcgcttgtc ccatatttcc aaaggtatct
     5101 ggaaagtagc caatctgggt tgatttaccc catttggcag cttcttgttg accaatcaag
     5161 gtattgcgga cattggcttc actggagatc aagtagtcat cctgcaagat gtaaaaggga
     5221 ccaattttaa gtttgccctc gtcaatgtag cgttggacct tgtcacgatt ttcagggcga
     5281 atttgtaagt agtcgtcaag gacaatagtt tgtccatcca agtggaaact cttgaactca
     5341 gggtcatttt caaagagatc aaagagattg tcaaacaatt ccaccaactg catacgatgg
     5401 ctttcaaaag gcaagtacca ctcacggtcc cagtgactat gtgagataat atgtacaaca
     5461 acattttcca tgaagtaaaa cctcattcta aatttaaatt ttaacgtttt aaatgtaaac
     5521 ttgtgattct gataagaatc ggttgagcta aagcgagccc cttagcgaat atccaagtaa
     5581 tccaagacca actcacagaa catcatgtta gcccaggaga accattcacg agagtagagg
     5641 gtcggatcat ctacatgaaa gctttcgtgc atgacacctg taccaccatc gcaggcaacc
     5701 agctgatcca gcaagaattt tttctctgcc ttatctcttg ttgtcaatcc ttggatagaa
     5761 agggcgattg gccagatata gcgatagaag gtatgagaac ttccgagacc gctagcgtat
     5821 tctccttggt agaaatatgg attttcagag ctcaaaatgg tacgacgagt agcttgatac
     5881 acttcatcat cgaccgaaca gtagcccaga tagggcgcag ctagtagact tggtacattt
     5941 ggatcatcca tgatgctggc atttcctagg ccatccactt caaaagcgta aatcttttcg
     6001 cccttgctgt tggtggtgta agcgtagttt ttgattcctt cttggatttc atcctgaaga
     6061 cgcttggcat cagcaataac actctggcta tcagctaggt ttaatgctgc gaagatttct
     6121 tgcacataac ccaagactac tacagcaaac atatttgacg gaatcaagta actatactga
     6181 cagcagtcat cgctcggacg aaaggctgac caagtcatac ctgtcactgc aaagtcaggt
     6241 ccaaagccat catttaccaa ggtgtcttcc ttacggtccg tatctcggac aaaacgataa
     6301 ggagagttct tgtggtcttg ttccaccgtc cacagatgga gaatttcctt agtcgctgcg
     6361 acaaaagtct catcaaactg actagtctcg ccagtctctt tccagaggag ataagccaac
     6421 tgcaaaggat agcaaagcga atccacctca tacttgcgct cccagatcca gccgttaagg
     6481 tctgtgtggt cagtctcgtg gtgccctttc cagttctcct caatgttgaa ggagttagca
     6541 tagggatcct tgagtaccaa ggtcatctga cgtttgacca aacctgcaat ggtctgacgc
     6601 aggagggcat ctcttttagc tacatgaagg tagggtctga gttgggctgt cgaatctcga
     6661 agccacatgg caggaatatc cccagtcaag acaaaagttg aaccatcttc taagatttca
     6721 accgtattgt ccaaggtatc ggtgtagcaa cgctcgaaaa catccaccca ctctggatgg
     6781 tccttagccc gctctgctac ttcatctagc cattctctaa caatttcttt cgaataaatc
     6841 atcgtgcaat tccctctttc aaacaagttt catgttcagt atatagcttt tgagacagaa
     6901 aatacataca caaatgatag tcatttttct acaaaatagt tatttttgaa actccttttc
     6961 taaaggccct ctttttctga tataatgtag aaaaacagct aaaggaaaga ctatgaaacc
     7021 actacttgaa accatcgata cccgctttgg tactgctagc aagcatgcct tctctcgggg
     7081 aaataccctg ccatacacag gcgtgccttt tgggatgaat tactttgtgc cccagaccag
     7141 tgaccagggt ggatcttggt tttttgatcc gcatctgcct atctttcagg ggattcgatt
     7201 aactcaccag cccagtcctt ggattgggga ctactcttgg ctccttctga cacctgtcac
     7261 cagtcaactg gggggagaca gcctctttca ccgccagtct tcttatgata tagataaagc
     7321 ttgcttccag cctcactatt tgaagctctt ttctctgcgt tatcagattg aaacccagct
     7381 cacaccgact tgctatggtg cttctattcg tttgaagcaa aagcaaggca aagccctctc
     7441 cctctatctt cacgcagcag atgaactgac agtagagcaa gtagataagc ggactcttgc
     7501 cctgcgacaa gaaggtaaaa ctgaaactaa caaaaattcg ctaacgatgt tcactgccct
     7561 gcaaatgaac acggatattc ttgctatcag ccaagaaggg ggagactggc gaattgactt
     7621 agcaagtagt caaaccgaga tgcaactagc cacttctttc atctctcctt ctcaagcact
     7681 gcttaatcta cctcaagaag attttgatag ctgtaaatca agtgcccaag cggattggga
     7741 aaatctcctc catcgttttg acattataga gataggagag gctgaccgaa ccttctttga
     7801 ccactgcctc tacagactct tcctcttccc acagactttt tatgagatta atgaatcagg
     7861 gcaagccatc cacatggatc tggctactgg tactgtcaag cctggtgtcc tctttagcaa
     7921 caatggtttc tgggatacct tccgcaccac cttccccctc tttgccctta tcataccgga
     7981 gcactatcaa cgctttttag aaggtttcct caatagctac cgcgatactg gtttccttcc
     8041 aaaatggctg gctccagatg aacggggtat gatgccaggt acacttttag acggtattat
     8101 cgcagatagc gcctgcaagg acatggcccc tgacctagaa ggagaactct tccaagccat
     8161 gctcgaaaca gccagcaaag ccgaccctct cggaatcaat ggccgccacg gactagccca
     8221 ataccaagaa ctaggttacc tctctaccga ccaccacgaa agtgttagcc atactctaga
     8281 ctatgcctat agtgactttt gtatcgccaa ctgtgccaaa aaactaaaaa acatagaaat
     8341 cgctgaaacc tacaaggctg cttcacaaaa ttaccgccag ctatttgacg ctgagacagg
     8401 ttacatgcga gcacgagaca atcaaggaaa ctttcaccct gacttctctc cttatagttg
     8461 ggggcgagac tacgctgaat gctctgccat tcaagctact ttaggcgttc tccacgacat
     8521 ccctggctta atccaactga tgggtggaaa agaaaccttt agcaactatc ttttgaaagc
     8581 ctgtcaagat gctcccctct ttgaaacaac aggctatggt tacgaaattc acgaaatgag
     8641 cgagatggct actgctcctt ttggacaaat agccatttcc aaccagccta gtttccacat
     8701 tccttatctc ttccgttaca gcgattaccc tgactacact gcccttctta tcaagacgct
     8761 ccgtcagaaa gcttttcacc caagttggga agcctatcct ggagatgaag acaatggtag
     8821 tctctctgct tggtacatct ggtcagctct cggattttat ccaacctgtc caggaaaacc
     8881 aagctatgac ctcggaatcc ctctctttga ccatctacga gtctacctcg ctaaagaaga
     8941 taaatggctg gatatccata ctaaacaaaa ccacaaccat tttaactttg tcaaagaatg
     9001 ccgactggac aaaacactcg tatcaactat tcaacaccaa gacctcttaa aagctgaaca
     9061 actaactttc accctcagct ggttaccaag tcattaataa ccaaaagaac ctttgcatcg
     9121 cgcaaaggtt cttcttttat gaaacttgga cttgaagttg atccacaagc tgaccatcca
     9181 ccgttaggtt cagatagaaa tccaaggttt tatctcctgc gaaatacagg gttggtagat
     9241 gcaaatcttt tttgctttcc cctgcttgga attgaaggac ttgaatctca tcctgatagg
     9301 cgacaccatg gacacctgtc cccggttgaa tcgaaatctt agcctctaaa gaggagctac
     9361 tttcactacg ttcaatccta aaatgaagag tctctccctt tgccacagct aggctttttt
     9421 ctgcaaatgc tagttcctga acaacttctt tttttgataa tccaggagtt ttataaaggg
     9481 aaatcttggt cagtagaggc atagattgtg cttcggtaat catcacgcgc accttctgtg
     9541 cctctactag cggacctcgc aagaggcgct tatgaccaac tgtgaagccc ctgccaaatt
     9601 cctgccagac accatccacc tctacttgca catggaaagc agaaatacgt tggcctaact
     9661 tcaaatcttc tctcaactca attacatcaa aagttttagg agaacctaag tcgagttcta
     9721 actggatggg caagtctgca tcgtttgccc aagagctggt ctcaaggccg tctgtcaaat
     9781 ggcgacaagc aaagtctgcg gaaagagctg gaccagatac ctcagctccc agagccaaat
     9841 cttctttata gagctcattg cgataggtcg caaattcata aagtcgttca atatcctttg
     9901 catcaaagag cccagcttga ttcggcggaa tattaagcaa gagtggagtt cctcgcccta
     9961 ctgagtgaaa gtagatttcg accaactcct cgagagactt aggatcctga tcctcatggt
    10021 agaaccagcc tggacggatg gaaacatctg cctctccgat tgaaaaaatc gtgcccgagg
    10081 gatccccgta ctgaagatag ttcagctctg cttctgttcc tagtttatca ggattcacct
    10141 tttgccacag tggatcacct gcataccctc gttcattgcc aatccagcgg atactggtgc
    10201 cttctgttga aaaaatcaag caatcgccct gcaggtcacg aatggtttca aaccattttt
    10261 caaattcata attaaccttt tgcgcgccct ctcctctggc accatccatc caaacctcag
    10321 cgaacttacc agcattccca tagttaggat ttgataagat ttccttcaac tgagccagat
    10381 aataggcatt gtagtccgct tctcggtcca catgatagag gggactatgg gcatcccacg
    10441 gtgacaggta gacccccata tccatatcaa actctgtggc agcttgggat acttcaagga
    10501 gcaagtcgcc ctttcctctc ctccaaggac tgaccttaac cgaataatct gtgtgagctg
    10561 tcggataaag gacaaagcca tcgtggtgct tgaccaccaa aatcaacttt ttgaagcccg
    10621 tttccttgag cacacgaacc cactcacgcg catccaactg actcgggtta aagcgctcag
    10681 gatcctcctg tccagtcccc cattcttggt cataaaaggt attaggaccg aagtggataa
    10741 aagctgctag ttcatctccc agataagcta gctgagtctg acttggtaac ggtccatgcg
    10801 gtttgatttt cttcatcgtt atatatctcc ttctttagca acttctcttg ttcacaaggt
    10861 tatccacagg ttgtggataa taaaaaatga tctaaccgcc agctctttcc aactccaact
    10921 ggtaggctca ggattttgct cctcaatgtt ccctcttcaa acagctctgt catatggttc
    10981 tgctaacacc tctcagaatg ctactctcca taattattct caggcttctt tcaggtcatt
    11041 gtgtgaagac cattcactct ccagactttt ccacagattg tgaataagtg attattctaa
    11101 actatcatct cgtcgactat aacaaaaaat aaaaagaggg tcaataagat aattatctct
    11161 tcctaaatac tcagaaaaga ttctataatt tgtacaattg agcaagaaat gcttctccaa
    11221 aatctatctt caaaagaatg ttgcatcttt ttatcctttc acacaaacat ttctctttat
    11281 acagatccaa gtgataacca gatgataatt ggacactttt tggttatttg tgtatttttt
    11341 gaaaaatttt ttaaaaaaat tttatatcct ctttaataga agtttatgca tttgtatata
    11401 tgtattccat cctatgttgt gtataataac ataaaattgt gctaaatatc ataatttata
    11461 ttattttccg agaaattata gccattgaca ttacctagga attgcgttat aacatacatg
    11521 taagcggtac ccaaaatggt gccaagtcaa aatttttaag gaggaaaata catgtcttca
    11581 catccaattc aggtcttctc agaaattggg aaactgaaaa aagttatgtt gcaccgtcca
    11641 ggcaaggagt tagaaaactt gttgccggac tatcttgaaa ggcttctttt tgatgatatt
    11701 cctttcttgg aagatgctca aaaagaacat gatgcatttg cccaagctct tcgcgatgaa
    11761 ggaattgagg ttctctacct agaacaactc gctgctgaat cattgacctc tccagaaatc
    11821 cgcgatcaat ttatcgagga atacttagac gaagccaaca tccgtgatcg tcaaaccaag
    11881 gttgctattc gtgaattgct tcacggcatc aaggacaacc aagaattggt tgaaaaaaca
    11941 atggctggga ttcaaaaagt tgaattgcca gaaattcctg acgaagctaa agatctaact
    12001 gacttagttg aatcagatta tccatttgca attgacccga tgccaaacct ctatttcact
    12061 cgcgacccat ttgcaacaat tggaaacgcc gtatcgctta accacatgtt tgcagacact
    12121 cgtaaccgtg aaacactcta cggtaagtat atcttcaaat accacccaat ctatggcgga
    12181 aaagtggatt tggtctacaa ccgtgaagaa gatacgcgta tcgaaggtgg agacgagcta
    12241 gttctttcta aagacgtcct tgcagtaggt atttctcaac gtacagacgc agcttctatc
    12301 gaaaaacttt tggtcaacat cttcaagaaa aatgttggct tcaagaaagt tttggccttt
    12361 gaatttgcta acaaccgtaa attcatgcac ttggatactg tcttcactat ggtagactat
    12421 gacaagttca ctattcaccc agaaatcgaa ggcgaccttc acgtttactc agttacttac
    12481 gaaaacgaaa aacttaaaat cgttgaagag aaaggtgact tagctgaact tcttgctcaa
    12541 aaccttggtg tagaaaaagt tcatttgatt cgttgcggtg gtggcaatat cgtagcagct
    12601 gcgcgtgaac aatggaacga cggttctaac actttgacca tcgcacctgg tgtggtagtt
    12661 gtttatgacc gcaataccgt gaccaataag attttggaag aatacgggct tcgcttgatt
    12721 aagattcgcg gaagtgaatt ggttcggggc cgtggtggac ctcgttgtat gtctatgcca
    12781 tttgaacgtg aagaagtgta atcgctgttc ggcattcgtc aatagaaaat gtaaaaaata
    12841 gaaagaggaa ataataaaat gacaaattca gtattccaag gacgcagctt cttagcagaa
    12901 aaagacttta cccgtgcaga gttagaatac cttattggtc tttcagctca cttgaaagat
    12961 ttgaaaaaac gcaatattca acaccactac cttgctggca agaatatcgc tctcctattt
    13021 gaaaaaacat ctactcgtac tcgtgcagcc tttacaactg cggctatcga ccttggtgct
    13081 cacccagaat acctcggagc aaatgatatt cagttgggta aaaaagaatc tactgaagat
    13141 actgctaaag tattgggacg tatgtttgac gggattgaat tccgcggatt cagccaacgt
    13201 atggttgaag aattggcaga attctcaggc gttccagtat ggaacggtct aactgacgaa
    13261 tggcacccaa ctcaaatgct cgctgactac ttgactgttc aagaaaactt cggtcgcttg
    13321 gaaggcttga cattggtata ctgtggtgat ggacgtaaca acgttgccaa cagcttgctc
    13381 gtaacaggtg ctatccttgg tgtcaatgtt cacatcttct caccaaaaga actcttcccc
    13441 gaaaaagaaa tcgttgaatt ggcagaagga tttgctaaag aaagtggcgc acatgttctc
    13501 atcactgaag atgctgatga agcagttaaa gatgcagacg ttctttacac agacgtttgg
    13561 gtatcaatgg gtgaagaaga caaattcgca gaacgtgtag ctcttcttaa accttaccaa
    13621 gtcaatatgg acttagttaa aaaagcaggc aatgaaaact tgatcttcct acactgcttg
    13681 ccagcattcc acgatactca cactgtttat ggtaaagacg ttgctgaaaa atttggtgta
    13741 gaagaaatgg aagtaacaga cgaagtcttc cgcagcaagt acgctcgcca cttcgatcaa
    13801 gcagaaaacc gtatgcacac tatcaaagct gttatggctg cgacacttgg taacctttat
    13861 attcctaaag tataatttta gataataaac cgtctaccaa cagctatgag ggctgcgact
    13921 aatagcttta gtccggtcct cttttatgta atggtaatct attatttctt ataaaatatg
    13981 tgaaaaatca ttaaattgaa atctaaacgc attctattga gtgtgataaa ggagaattta
    14041 tggcaaatcg taaaattgta gtagctttgg gaggaaatgc gattctttct tctgacccat
    14101 cagcaaaggc tcaacaagaa gctttagttg aaacagctaa gcatcttgta aaattgatta
    14161 aaaatggaga tgatttgatt atcactcacg gtaatggacc tcaagttggg aatctcttgc
    14221 tccaacattt ggcatcagac tctgaaaaga accctgcctt cccactcgac tcacttgtcg
    14281 ctatgacaga aggtagcatc ggtttctggt tgaaaaatgc tttgcaaaat gctctcttgg
    14341 atgaaggcat cgaaaaaaat gttgcctctg ttgtaacgca agttgtcgta gataaaaatg
    14401 atccagcttt tgttaacttg agtaaaccaa tcggtccttt ctattcagaa gaagaagcaa
    14461 aagcagaagc cgaaaaaagc ggagcgactt tcaaggaaga tgctggccgt ggctggcgta
    14521 aggtcgttgc ctcaccaaaa cctgttgaca tcaaagaaat tgaaaccatc cgtactcttt
    14581 taaataatgg tcaagtcgtc gtagctgcag gtggtggcgg tattcccgtc gtcaaagaaa
    14641 acaatggaca tttgactggt gtcgaagcgg ttattgataa agacttcgct tcccaacgtt
    14701 tggcagaatt ggttgatgca gacctcttca tcattttgac aggtgtagat tatgtatttg
    14761 ttaactacaa caagccaaac caggaaaaat tggaacatgt gaatgttgcc cagctggaag
    14821 aatatatcaa acaagatcag tttgcaccag gtagcatgct tccaaaagta gaagcagcta
    14881 tcgcttttgt caatggtcgt ccagaaggaa aagcagttat tacttccctt gaaaatctag
    14941 gcgccttgat tgaatctgaa agtggaacaa ttattgaaaa aggataagtt gttttactaa
    15001 taagatgtat tctatttcta gtatctttat atcaaattag aaattattct tgaaaacatg
    15061 tacaatattt caaaagatat tagtttttta gactttaata tggtaaaaca aatataaata
    15121 gaaagcgttt tcttaaatgt ttatttaaga aagtagttgg ttttttacac tttgttagac
    15181 atcaggagga aaaacaaatg agtgaaaaag ctaaaaaagg gtttaagatg ccttcatctt
    15241 acaccgtatt attgataatc attgctatta tggcagtgct aacttggttt atccctgcgg
    15301 gggcctttat agaaggtatt tacgagactc agcctcaaaa tccacaaggg atttgggatg
    15361 tcctcatggc accgattcgg gctatgctag gtactcatcc agaggaaggt tcgctcatta
    15421 aagaaacgag cgcagcgatt gatgtagcct tcttcatcct tatggttggt ggtttccttg
    15481 gcattgtcaa caaaactggt gctcttgacg tagggattgc ctctatcgtg aagaagtata
    15541 agggccgcga aaaaatgtta attttggtac tgatgccttt gtttgccctc ggtggtacaa
    15601 cttatggtat gggtgaagaa acaatggctt tctatccact ccttgtgcca gttatgatgg
    15661 ccgttggttt tgatagcctg actggtgttg caattatttt gctcggttct caaatcggct
    15721 gtttggcatc tactctgaat ccatttgcga caggtattgc ttcagcgact gcgggagttg
    15781 gtacagggga cggtatcgta cttcgtctga tcttctgggt taccttgact gctcttagta
    15841 cttggtttgt ttaccgttat gcggataaga ttcaaaaaga tccgactaag tcactggttt
    15901 atagtactcg caaagaagat ttgaaacact ttaacgtaga agaatcttca tctgtagaat
    15961 ctacacttag cagcaaacaa aaatcagttc tcttcttatt tgtgttgaca ttcatcttga
    16021 tggtattgag cttcattcca tggacagacc ttggcgttac catttttgat gactttaata
    16081 cttggttgac tggtcttcca gttattggta atattgtcgg ttcatctact tctgcactag
    16141 gtacttggta cttcccagaa ggcgcaatgc tctttgcctt tatgggtatc ctgattggtg
    16201 ttatttatgg tcttaaagaa gataagatta tctcttcctt catgaatggt gctgctgact
    16261 tgctcagtgt tgccttgatc gtagcgattg ctcgtggtat tcaagttatc atgaacgacg
    16321 gtatgattac cgatacaatc ctcaactggg gtaaagaagg cttgagcggt ctatcttcac
    16381 aagtctttat cgttgtaact tatatcttct atctacctat gtcattcttg atcccatctt
    16441 catctggtct tgccagcgca actatgggta tcatggctcc acttggagaa tttgtaaatg
    16501 tccgtcctag cttgattatc actgcttacc aatctgcttc aggtgtcttg aacttgattg
    16561 caccaacatc tggtattgtg atgggagctc ttgcacttgg acgtatcaac attggtactt
    16621 ggtggaaatt catgggcaaa ctcgtagtcg ctattattgt agtgaccatc gcccttcttc
    16681 tccttggaac cttccttcca ttcctataaa atagtgagtg aggtgattcc atgaaaatag
    16741 atataacaaa tcaagttaaa gatgaatttc ttatatcatt aaaaaccttg atttcctatc
    16801 cttcagtact caatgaagga gaaaatggaa caccttttgg acaagcaatc caagatgtcc
    16861 tagaaaaaac tttagagatt tgtcgagaca taggtttcac tacctatctt gaccctaaag
    16921 gttattacgg atatgcagaa atcggtcagg gagcagagct tctggccatt ctctgtcatt
    16981 tggatgttgt tccatcaggt gatgaagcag attggcagac accgccattt gaagcaacta
    17041 tcaaagacgg ctgggtattc ggacgtggtg tccaagatga taaaggccct tcgctcgcag
    17101 ctctctatgc agtaaaaagc ttgctggacc aaggtattca gttcaaaaag cgcgtacgct
    17161 ttatctttgg taccgatgag gaaaccctct ggcgctgcat ggcacgctac aataccatcg
    17221 aagaacaggc cagtatgggc tttgcacctg actcatcttt tcctctgacc tatgctgaaa
    17281 aagggcttct acaggtcaaa cttcatggcc ctggatcgga tcaactagag cttgaagtag
    17341 gaggcgcctt taacgttgta ccagacaagg ccaactacca aggtcccctc tatgaacagg
    17401 tttgtaacgg tctcaaagaa gctggttatg attaccaatc cactgaacaa accgtaacgg
    17461 ttctcggagt gccaaagcat gctaaggatg ctagtcaagg tatcaatgct gtcatccgac
    17521 tagctaccat tcttgctcct ctccaagaac accctgctct cagttttctt gcaacacaag
    17581 caggtcaaga cggcacagga agacaaatct ttggtgatat agcagatgaa ccttctggtc
    17641 acctatcctt taatgtcgca ggtctcatga tcaatcatga acgttctgaa atccgtattg
    17701 acattcggac tcctgtctta gctgacaagg aagaactagt agagttgctt acaagatgtg
    17761 cacaaaacta ccaactccgc tacgaagagt ttgactatct agcgcctcta tacgtcgcaa
    17821 aagacagtaa actcgttagc acactgatgc aaatctacca agaaaagact ggcgataaca
    17881 gtcctgctat ttcatccggt ggtgccactt ttgctcgcac catgccaaat tgtgtagcct
    17941 tcggcgcctt attcccagga gcgaagcaaa cagaacatca ggcaaatgaa tgtgccgttc
    18001 tagaagattt gtaccgtgct atggatattt atgccgaagc cgtctatcga cttgcaactt
    18061 aatcaggcaa ctgtttctac caaaaaaaat cgaccgatta atgaactgca ccccaaaagt
    18121 tagacagaat aaatctaact tttggggtgt tttattatga aattgagtta tgaagataaa
    18181 gttcagatct atgaactaag aaagcaagga caaagcttca aacagctttc aaaaagattt
    18241 ggtgtggatg tttctggtct aaagtacatg gtgaaattaa ttgaccgtta tggcatagaa
    18301 atcgttaaaa aagggaagaa tcgtcactat tcttctaaat tgaaacaaga aatgatggat
    18361 aaagccttac tggaaggttg ttcacaaaga agtattagtc ttgattatgc cctcccaaac
    18421 caaggaatgc tttcattttg gccggcacaa tacaagaaaa acgggtatac tattgttgag
    18481 aaaacaagag ggagaccagc taaaatggga cgtaaacgga agaagacttg ggaagaaatg
    18541 acagaactag aacgactcca ggaggagaat gaacgcttac ggactgaggt ggcctaccta
    18601 aaaaagttaa aagagttaga ggaaagggac gaagccctag agcgagaaag gcagagacag
    18661 ttagagaaat ggtttcagga ggatttcgac tagattttct tcttgaaaca gcacgtttag
    18721 ctcgctcgac ttactattat cagttgaaac aactggatgg ggttgataaa gataaagaga
    18781 ttaaaaccga aattcagggc attgataatg aacataaagg caactatggc tatcgtcgaa
    18841 tccatttaga actaaggaat cgtggttttg tggtcaatca taagaaagtt caacggttga
    18901 tgagaattct tggtttaacg gctcgaattc gccgtaaacg gaagtattct tcctaccaag
    18961 gagagattgg caagaaagca gagaatctca ttcaacgcca gttcgaagca tcgaggccaa
    19021 tggaaaagtg ctatacagat gtgacagagt ttgccattcc aaatagcaca cagaaactct
    19081 atttatcacc agttttagat ggttttaaca gtgaaatcat tgcttatcat ctttctactt
    19141 cgccaaactt agaacaagtg aagagtatgt tagaacaggc ctttacagag aaatactatg
    19201 agaatacgat tctccatagt gaccaaggct ggcaatacca acacgattct tatcatcggt
    19261 tcctagagag taaggaaatt caagcatcca tgtcacgcaa gggcaacagc ccagacaacg
    19321 gcatgatgga atctttcttt ggcattttaa aatccgaaat gttttatggc tatgagaaga
    19381 actttagatc tttagaaaac cttgaacaag ctattgtgga ctacattgat tactacaaca
    19441 acaaacgaat taaggtaaaa ctaaaaggac ttagttctgt gcagtacaga actaaatcct
    19501 ttggataaat tatttgtcta attttttggg gtcagtacag tattaaatac catgatctta
    19561 tgcgttttat aataaaaaat ctgttcttgt tttattttta gaaaatttac taaagactaa
    19621 aaatattatg aataatttaa aaaatagtca ggttatatag ttttttgaaa ttaaaattat
    19681 tttatcgttg aaattagtta aaaattttta taaaatcaag atgcaaggct atgagatgtt
    19741 ctctagttta atttttcata cttcgagaat ataaagttat ataaaaatgc attagcatat
    19801 tttgttattg agggaagtat aaaaatcatt aaagttatcc aaactagtaa ttgattctgt
    19861 aatataaaga agagtagaac tgggataatt tcaataattc taataagaac ggcaataaaa
    19921 aaatgtttat aggctaacat gattgaattg tgtagagaat tttttaaagt gttattatat
    19981 ctaccgatta aaggaattag aaatgttgtt gctattaaat gaagtatgat atatattact
    20041 ccaatatgtc gtaagataga aatgatatat ataggtaatg gtatgtaggg taggaagaac
    20101 aaactgaata ataagattaa aattggtaaa ttagatatta atgctgctcc taaatttttc
    20161 caataatctt taaaaaaact gtttgcgaag tctctatagg gataggattc ctcgtgtcgt
    20221 acaattttta ttagagttgc tattagggca ctttcacctg atccgatagc aataactgtt
    20281 actactgacg ctacatagag tagatttaac attataagat ttgaaacttt atcaataaat
    20341 tttatctgca tctttaactc ctgctgtttt tatacttata atatcacatc atttgagttt
    20401 catcaacttt gaatacatta agaaagaata taactatgag gaaaggaaaa aattattatg
    20461 aataaatcca aaaaatataa agaaagaatt cattatgaat acgataatct tactaaatca
    20521 gagaaaaaat tgctgactat attttagtta gagatagtga aatagtttat gaaacgtctt
    20581 cagaaattgt tagtaaagta aaagttggag agggaactct taatcgattt tgcaaaaaga
    20641 ttggatactc tggttttcag gaactaaaat taaaaatgac gaaagatata ttagagttag
    20701 aatctcaaaa aatgagtagt gacacattta ttgatgaaat aaaaaataat tatttatcta
    20761 ttgtggaaag tacaagaaaa ttaattgatg gtagacaaat agaattagct ataaaattaa
    20821 taagagaagc aaaccagatt ttaatgattg gtgtgggttc tagtggaaat gcggctagag
    20881 aatttgagag tagtttgtta agaattggaa taataagtaa gacggtaatt gatacccatt
    20941 ttcaactcat gcatactgcg ttattgaaag ataatgattt gataatagcg tttagtttat
    21001 ctggttccac aaaagaagtt gaggaaactt tattaaacgc aaaaagaaaa aatgttaaaa
    21061 ttatttcaat aacaaattat tcgtccagaa atatagcaaa attatctgac tgcgttcttt
    21121 tgacatcaaa aaaagaatct tatttagagg gtggtagttt aatggctaag gcttctcaac
    21181 tattcataat tgatgtaata tgcactagac tctctttaat aaattatgaa gatactatat
    21241 gtaaaaaaga agagattgct tctttgctgt caaataaagt ggaataaatc aataattttt
    21301 aaattttaat aaaaattttt
//
LOCUS       DBERXF010000039        21269 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.39, whole genome shotgun sequence.
ACCESSION   DBERXF010000039 DBERXF010000000
VERSION     DBERXF010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21269
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.39"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..197)
                     /locus_tag="ACL8JK_001642"
     CDS             complement(<1..197)
                     /locus_tag="ACL8JK_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGS1786496.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLET"
     gene            391..888
                     /locus_tag="ACL8JK_001643"
     CDS             391..888
                     /locus_tag="ACL8JK_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGS1786497.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            888..2543
                     /gene="dnaX"
                     /locus_tag="ACL8JK_001644"
     CDS             888..2543
                     /gene="dnaX"
                     /locus_tag="ACL8JK_001644"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGS1786498.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PALSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLAGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2571..2765
                     /locus_tag="ACL8JK_001645"
     CDS             2571..2765
                     /locus_tag="ACL8JK_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HGS1786499.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2915..3685
                     /gene="sufC"
                     /locus_tag="ACL8JK_001646"
     CDS             2915..3685
                     /gene="sufC"
                     /locus_tag="ACL8JK_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGS1786500.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3713..4975
                     /gene="sufD"
                     /locus_tag="ACL8JK_001647"
     CDS             3713..4975
                     /gene="sufD"
                     /locus_tag="ACL8JK_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGS1786501.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFY
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4986..6212
                     /locus_tag="ACL8JK_001648"
     CDS             4986..6212
                     /locus_tag="ACL8JK_001648"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGS1786502.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAIEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            6199..6639
                     /gene="sufU"
                     /locus_tag="ACL8JK_001649"
     CDS             6199..6639
                     /gene="sufU"
                     /locus_tag="ACL8JK_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGS1786503.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6689..8101
                     /gene="sufB"
                     /locus_tag="ACL8JK_001650"
     CDS             6689..8101
                     /gene="sufB"
                     /locus_tag="ACL8JK_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGS1786504.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8332..9573)
                     /gene="pbp3"
                     /locus_tag="ACL8JK_001651"
     CDS             complement(8332..9573)
                     /gene="pbp3"
                     /locus_tag="ACL8JK_001651"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HGS1786505.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKNLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9676..10785
                     /gene="cozE"
                     /locus_tag="ACL8JK_001652"
     CDS             9676..10785
                     /gene="cozE"
                     /locus_tag="ACL8JK_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HGS1786506.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11431..11778
                     /gene="ssrA"
                     /locus_tag="ACL8JK_001653"
     tmRNA           11431..11778
                     /gene="ssrA"
                     /locus_tag="ACL8JK_001653"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11950..12037)
                     /locus_tag="ACL8JK_001654"
     tRNA            complement(11950..12037)
                     /locus_tag="ACL8JK_001654"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12001..12003),aa:Ser,seq:gga)
     gene            12199..12939
                     /locus_tag="ACL8JK_001655"
     CDS             12199..12939
                     /locus_tag="ACL8JK_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS1786507.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAVSLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12936..13847
                     /gene="pfkB"
                     /locus_tag="ACL8JK_001656"
     CDS             12936..13847
                     /gene="pfkB"
                     /locus_tag="ACL8JK_001656"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGS1786508.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVELVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAELIKETYGKVEVEKR"
     gene            13844..15796
                     /locus_tag="ACL8JK_001657"
     CDS             13844..15796
                     /locus_tag="ACL8JK_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGS1786509.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGSLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15933..18185
                     /locus_tag="ACL8JK_001658"
     CDS             15933..18185
                     /locus_tag="ACL8JK_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGS1786510.1"
                     /translation="MERKEAIQRMLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGS
                     LAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGT
                     MAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWS
                     VYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPP
                     VDMETGEILTEEAVQNLPPIPEEKWVEPEIILSQAELKFPEQEDDSDDEDVQVDFSAK
                     EALKYKLPSLQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVT
                     KYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFR
                     ELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASI
                     LMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYEL
                     FAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRL
                     GQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLL
                     GRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGE
                     FSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAE
                     GTKPRKVLQQ"
     gene            complement(18228..18659)
                     /locus_tag="ACL8JK_001659"
     CDS             complement(18228..18659)
                     /locus_tag="ACL8JK_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HGS1786511.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENKSNQ"
     gene            18797..19939
                     /locus_tag="ACL8JK_001660"
     CDS             18797..19939
                     /locus_tag="ACL8JK_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGS1786512.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKIDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIHQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19948..21162
                     /gene="thiI"
                     /locus_tag="ACL8JK_001661"
     CDS             19948..21162
                     /gene="thiI"
                     /locus_tag="ACL8JK_001661"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGS1786513.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
BASE COUNT         6233 a         3931 c         4704 g         6401 t
ORIGIN      
        1 gtttcgaggt aagggatctt agacggtttt tgaaagtcat atttcttcat tagacttcca
       61 caatcagggc aagatggagc ctcataatcc agcttagcga taatttcttt gtgggtatcc
      121 atattgatga tatctagaat cttgatgttt gggtctttaa tatcgagcag ttttgtgata
      181 aaatgtaatt gttccatatg attctttcta atgagttgtt ttgtcgcttt tcattatagg
      241 tcatatggga ctttttttct acacaaaaat aggctccata atatctataa gggatttacc
      301 cactacaaat attatagagc ccaaaatcct ttgtttacta aacaagggat ttttcttttg
      361 tctctgctcc ttttttgata taatagttct atgttaaaat cagaaaaaca atcacgttat
      421 caaatgttaa atgaagaatt gtccttccta ttggaaggcg aaaccaatgt tttggctaat
      481 ctttccaacg ccagtgctct tataaaatca cgttttccta ataccgtatt tgcaggcttt
      541 tatttgttcg atggaaagga attggtttta ggtcccttcc aaggaggtgt ttcctgcatc
      601 cgtattgcac taggcaaggg tgtttgtggt gaggcagctc actttcagga aactgttatt
      661 gttggagatg tgacgaccta tctcaactat atttcttgtg atagtctagc taaaagtgaa
      721 attgtggtgc cgatgatgaa gaatggtcag ttacttggag ttctggatct ggattcttca
      781 gagattgagg attacgatgc tatggatcga gattatttgg aacaatttgt cgctattttg
      841 cttgaaaaga caacatggga ctttacgatg tttgaggaaa aatcttaatg tatcaagcac
      901 tttatcgaaa atatagaagt caaaacttct cccagttagt tggtcaagaa gttgtggcta
      961 agactcttaa acaagcggtg gagcaagaga aaataagtca cgcttatctt ttttctggtc
     1021 ctcgtggaac gggaaaaacc agtgttgcta aaatctttgc caaggctatg aactgtccca
     1081 atcaagtggg tggcgaacct tgcaataact gctatatttg tcaagcagtg acggacggta
     1141 gtttagaaga tgtcattgaa atggatgcag cttctaataa tggggtagat gaaattcgcg
     1201 aaattcgtga taaatctacc tatgcaccta gccttgctcg ttataaggtt tatatcatag
     1261 atgaggttca catgctgtct acaggggctt ttaatgccct cctaaagacg ctggaagaac
     1321 caacacagaa tgtagtcttt attttggcca ctactgaatt gcacaagatt cctgctacta
     1381 ttctatcccg tgtgcaacgt tttgagttta aatcaattaa gacacaggat attaaggaac
     1441 atattcacta tatcttagaa aaagaaaata tcagttctga accagaggct gtggaaatca
     1501 ttgccagacg ggcggaaggt ggaatgcggg acgccttgtc tattttggat caagccctga
     1561 gtttgacaca gggaaatgag ctgacgactg ctatctctga agaaattact ggcaccatta
     1621 gcctatcagc cttggatgat tatgtggcgg ccttgtctca acaggatgtt cccaaagctt
     1681 tgtcttgctt gaatcttctt tttgacaatg gtaagagcat gactcgtttt gtgaccgatc
     1741 ttttgcacta tttaagagac ttgttaattg ttcaaacagg gggagaaaat actcatcata
     1801 gttcagtctt tgtagaaaat ttggcacttc ctcaaaaaaa tctgtttgaa atgattcgct
     1861 tagcaacagt gagtttagca gatattaagt ctagtttgca gcccaagatt tatgctgaaa
     1921 tgatgaccgt ccgtttggcg gaaatcaagc ccgaaccagc tctatcagga gcggttgaaa
     1981 atgaaattgc tacgctgaga caggaagttg cccgtctcaa acaagagctt tctaatgtag
     2041 gtgcggttcc taaacaagtt gcaccagctc ttagtcgacc agctacgggc aaaacagtct
     2101 atcgtgtcga tcgcaataaa gtgcaatcta tcttacaaga ggccgtcgaa aatcctgatt
     2161 tagcacgtca aaatttaatt cgtttgcaga atgcctgggg agaggtaatt gaaagtctag
     2221 gtgggccgga caaggctctg ctagctggtt ctcaaccggt tgctgccaat gaacaccatg
     2281 ctattcttgc ttttgagtct aacttcaatg ctggtcaaac tatgaaacga gacaatctca
     2341 ataccatgtt tggtaatatc ctcagtcagg cggcaggttt ttcacctgag attttagcta
     2401 tttccatgga ggaatggaaa gaagttcgcg cagccttttc agccaaagcc aaatcttctc
     2461 aaactgaaaa agaagtagaa gaaagcctga ttccagaagg atttgaattt ttggctgata
     2521 aagtgaaggt agaggaagac taaagaaaga tttcatgata caataagttt atgaataaac
     2581 aacaatttat tattatggcg ctgtttacag ctgctgagac ctattttttc aatgaagcct
     2641 ggatgactgg ccgctatatt atggcagcct tttgggcaat tttactcttt agaaatttcc
     2701 gagtcagtta tgtgatgggc aaaatcgttg atgtcatcga tcagcatttt aataggaaag
     2761 actagccctc agcttccaga caaaatcaaa gccttttagg cttttttttg ttatactaga
     2821 aaagtatatt tatagaattt ttgctctatt tctggggaaa tcagacgttt ttctagtaag
     2881 tactgtaaaa gttttgaaaa agaaaggaac tatcatgtca gtattagaga tcaaagatct
     2941 tcacgttgag attgaaggaa aagaaatttt aaaaggggtt aacctgaccc tgaaaacagg
     3001 agaaattgcc gctatcatgg gaccaaatgg tacaggtaaa tcgactcttt ctgccgctat
     3061 catgggaaat ccaaactatg aagtaactaa aggtgaagtt ttgtttgatg gcgtaaacat
     3121 ccttgagttg gaagtggatg agcgtgcgcg tatgggactt ttccttgcta tgcaataccc
     3181 atcagaaatc cctggaatta ccaatgctga gtttcttcgt gccgctatga atgcgggtaa
     3241 agaagatgat gagaagattt cagttcgtga gtttattact aagctagatg aaaaaatgga
     3301 attgctcaac atgaaagaag aaatggcaga gcgttacctc aacgaaggct tctctggtgg
     3361 tgagaaaaaa cgcaatgaaa ttcttcaact tttgatgttg gagccaacat ttgctctttt
     3421 ggacgagatt gactcaggtc ttgatattga cgctcttaaa gttgtgtcta aaggtgtcaa
     3481 tgccatgcgt ggtgaaggtt ttggtgctat gatcatcact cactaccaac gtcttttgaa
     3541 ctatatcaca cctgatgtgg tacacgtgat gatggaaggt cgtgttgtcc tttctggtgg
     3601 tccagaattg gctgcgcgtt tggaacgtga aggatacgca aaattagctg aagaacttgg
     3661 ctacgactac aaggaagaat tgtaatttcc tcgtatcttt taggagaagt aaatgactag
     3721 agaaaatatt aaactttttt cagaaatgca cgctgaacca agctggttgg ctgatctccg
     3781 tcaaaaagct tttgacaaga ttgagacttt ggaattacca gttattgagc gtgtcaaatt
     3841 ctaccgttgg aatctgggtg atggaacgat tacagaaaat gagccatcag caaatgttcc
     3901 agatttcaca gctttagatc atcacttgaa gttggtgcaa gtaggaactc aaactgtttt
     3961 cgaacaaact ccagttgagt tagctgaaca gggtgttgtc ttcacagact ttcactcagc
     4021 tttagaagaa attccagagc tgatcgaaga attcttcatg tcatctgtta agtatgatga
     4081 tgacaagttg gcggcttacc acacagctta ctttaacagt ggtgctgtac tctatattcc
     4141 agataatgta gaaattacag agccaattga aggaattttc taccaagata gcgatagcaa
     4201 tgtgccgttt aacaagcata ttatgattat cgctggtaaa aattctaaga ttagttatct
     4261 ggagcgttta gagtcacgcg gtgaaggaag tgacaaagca actgccaata tcacagtgga
     4321 agtgattgca cgttctggtg cgcaagtcaa gtttgctgct atcgaccgtc taggtgaaaa
     4381 cgtcactgcc tacattagcc gtcgtggtaa attaggcaac gatgcaagta ttgactgggc
     4441 tatcggtgtc atgaacgaag gaaatgtcgt tgctgatttt gatagtgact tgattggtaa
     4501 tggtagccat gctgacctca aggttgtagc tctttcaagt ggtcgtcagg tacaagggat
     4561 tgatactcgt gtaactaact atggctgcaa ctcaatcgga aacattctac aacatggggt
     4621 tatccttgaa aaagcaactt tgactttcaa tggtatcggc cacatcatca agggtgctaa
     4681 gggagcagat gcgcaacaag agagccgtgt tctcatgctt tcagaccaag cgcgttcaga
     4741 tgctaaccca attcttttga ttgatgaaaa tgacgtaact gcaggacatg cagcctctat
     4801 tggtcaggta gatccagaag acatgtatta cctcatgagt cgtggattgg ataaggcaac
     4861 tgcagagcgt ttggttgttc gtggtttcct tggatctgtt atcgtggaga ttccagtcaa
     4921 ggaagttcgt gatgaaatga ttgcaactat cgaagagaaa ttgtcaaaac gctaagggga
     4981 agcctatgtt agatgtagaa gcgattcgca aggattttcc aattttagat cagattgtca
     5041 atgatgaacc tctggtctat ctggacaatg ctgcgacgac acaaaaacca ctagtagttc
     5101 tgaaagctat taacagctac tatgagcagg acaatgccaa tgttcaccgt ggtgtccata
     5161 ccttagcgga acgagcgaca gcttcttatg aagctgctcg tgaaaccatt cgtaagttta
     5221 ttaatgcagg ctctacaaag gaagttctct ttaccagagg aacgacaacc agccttaact
     5281 gggtggcacg ctttgctgag gaaattctca ctgagggaga ccaggtcttg atttcagtaa
     5341 tggaacacca ttctaatatc attccatggc aggaagcttg tcgaaagact ggagcagagc
     5401 ttgtctatgt ctatcttaaa gacggtgcct tggatatgga ggatttgcga gctaaattga
     5461 ctgataaggt taaatttgtt tccctagctc atgcctccaa tgttcttggt gtggtcaatc
     5521 cgatcaagga aatcactcaa ttagcccacc aagttggggc aatcatggta gtggatggtg
     5581 ctcaatctac acctcatatg aagattgatg tccaggactt ggatctggac tttttcgcct
     5641 tttcgggtca caagatggct ggtccgactg gtatcggtgt cctttacggc aaagaaaagt
     5701 atcttgagca aatgtctcca gtagaatttg gcggcgagat gattgatttt gtctacgagc
     5761 aatctgctag ttggaaggaa ttgccttgga aatttgaggc tggaacgcca aatatggcag
     5821 gagctattgg acttgcgact gcagttgatt atctggaaaa gattggtatg gatgccattg
     5881 aagctcatga acaggaattg attgcgtacg tctatccaaa actgcaggca attgagggat
     5941 tgaccattta cggttctcag gatttggctc aacgttcggg tgttattgcc tttaacctag
     6001 gtgatctcca tcctcacgat cttgcgacgg ctctggatta tgaaggagtg gctgttcgtg
     6061 ctggtcacca ttgtgcgcaa cccttgcttc agtatttgga agtcccagca acagctcgtg
     6121 caagttttta tatctacaat accaaggcag attgcgacaa actagtcgat gccctacaaa
     6181 agacaaagga gtttttcaat ggcactttct aaactagata gcctttatat ggcagtggta
     6241 gcagaccatt cgaaaaatcc acatcaccaa gggaagttag aagacgctga gcaaatcagt
     6301 ctcaacaatc cgacttgtgg ggatgtcatc aacctctctg tcaagtttga tgcagaggac
     6361 cgtttggaag atattgcttt tctaaattca ggatgcacga tttcaactgc ttctgctagt
     6421 atgatgacag atgccgtttt aggaaaaacc aaacaagaaa ttttagaact ggcgactatt
     6481 ttttctgaaa tggttcaagg gcaaaaagat gagcgtcaag accaacttgg agacgcggca
     6541 ttcttgtcag gtgttgccaa attccctcaa agaatcaagt gtgcaaccct agcttggaat
     6601 gcccttaaga aaacaattga aaatcaagaa aaacagtaag acaagtttct tttgtcttat
     6661 gaattattag aaatgaagaa aggatattat ggctgaagaa agagtagaac caaaaccaat
     6721 tgaccttggt gaatataaat ttggtttcca tgacgatgta gagcctgtct tatcgacagg
     6781 aaaaggactc aacgaaggtg ttattcgtga attatctgct gctaagggtg agcctgagtg
     6841 gatgttggag ttccgtttga agtcttatga aaccttcaaa aaaatgccca tgcaaacttg
     6901 gggagcagac ttgtcagaga ttgactttga tgacttaatc tactaccaaa aaccatctga
     6961 caaaccagcc cgttcttggg atgatgtacc tgaaaagatt aaagaaacct ttgaacgtat
     7021 cgggattcca gaagctgaac gtgcttattt agcaggggct tctgcccagt acgagtcaga
     7081 agtggtttac cacaacatga aggaagagtt ccaaaaatta ggtattatct ttacagatac
     7141 agattccgca ctcaaggaat acccagactt atttaaacaa tactttgcga agttggtacc
     7201 gccgacagat aacaagttgg cagccctcaa ctcagcagta tggtcgggtg gaacttttat
     7261 ctacgtgcca aaaggtgtca aggtagatat tccacttcaa acttatttcc gtatcaataa
     7321 cgaaaatata ggtcagttcg aacgtacctt gattatcgtt gatgagggag caagcgtcca
     7381 ctacgtagaa ggatgtacag caccaacata ttcaagcaat agcttacacg ctgccattgt
     7441 agaaattttt gctttggacg gagcttatat gcgttataca actatccaaa actggtctga
     7501 taacgtctat aacttggtaa caaagcgtgc taaggctcaa aaggatgcca ctgttgagtg
     7561 gattgatgga aacttgggtg ccaaaacgac tatgaaatat ccatctgttt accttgatgg
     7621 agaaggagcg cgtggtacca tgctctctat cgcctttgct aatgcagggc aacaccaaga
     7681 cacgggtgct aagatgattc acaatgctcc acataccagc tcgtctattg tgtctaaatc
     7741 catcgctaaa ggtggaggaa aggttgacta ccgtggacaa gtcaccttta acaagaactc
     7801 taagaaatct gtttcccaca ttgaatgtga taccattatc atggatgact tgtcagcatc
     7861 agatactatt ccatttaatg aaattcacaa ctcgcaagtg gctttggaac acgaagccaa
     7921 agtatctaag atttcagaag agcaattgta ttatctcatg agccgtggat tgtcagaatc
     7981 tgaggcaact gaaatgattg tcatgggatt tgtagaaccc tttacaaaag aacttccaat
     8041 ggaatacgca gttgagctga accgcttgat tagctatgaa atggagggat cagttggata
     8101 aaatttgatt ttatactctt cgaaaatctc ttcaaaccac gtcagcatcg ccttaccgta
     8161 tgtatggtta ctgacttcgt cagtttcatc tacaacctca aaacagtgtt ttgagcaacc
     8221 tgcggctagc ttcctagttt gttctttgat tttgagtatt agatttactc aaaatcaagg
     8281 attttgaaga tgaacttgta tcaaaaaatc gcggtttaaa atcgcgattt tttataattt
     8341 ctcgttaaca aagcggacaa actgattcca ccaaactttt aagaagaagg ctttttcaat
     8401 tttcttgtct gctaccattt cgaaactagg gcgctctgtg gtgatgtaac cttgaccaat
     8461 caagttcttg tcttcataag tcaaatggcc aaccactgtt ccagcttcaa gtggtgctgg
     8521 gattgctttg gaatcaggtg tgaattgaac agattgggaa gattgattcc caacacgttc
     8581 tattagatag atatcctctg gagccactgc agttactgta tcttcttttc catcttgtac
     8641 aggggctttg ctatcttgat aggcatcgcc ttgttgaacg attttgcgaa gtgtaaatgt
     8701 agaagaaata taatccatta gggaagatgt agctgtaaat cgagcgtaag gattattgtc
     8761 ttgatgatct gcatttaaaa caactgtgat gactctcatg cctttttcga cagtagtacc
     8821 aacaaaagac tctccagcct tatctgttgt tcctgttttt agcccatcaa aaccaccacg
     8881 gtaagcaggc ataccttcta acatgtagtt ggttgaagtg attgtcatcc cagcaaaagt
     8941 agaagaaggt tttttggtga tttctaagac ttgtgggtat tttttgatga ggttgcgagc
     9001 aacgatagcg acatcataag cactaagctt attttcctca tcttttttag aacctgggta
     9061 aatgttatcc cctagagttt cattgttaag acctgtcgta ttgacaacag tggcatcctg
     9121 aattccccat tccaagagtt ttgcccgcat catatcgacg aaatcttttt ctgagccagc
     9181 aattttctca gctagggcaa tagcggcgct gttggcacta gataccagag ttgcttcaag
     9241 caactcttcg acagtataat tacgggcctc cataggaata ttactggctt cagaatttgt
     9301 cgtcaattga taaggataat cagaaatatc tacaggagtg gagagggtaa tacttccgtt
     9361 ttccaaagct tcatagacca gataaacagt aatcaatttt gttatggaag caatttcgac
     9421 aggttgcgtt gcatccttct catagagaat tttaccagta tttgcctcaa cagcaatcgc
     9481 atgtttagcg gcaatggtaa aatcttgagc aacagcagta gaagcacccc ctaaaagaga
     9541 gacagttaac aaagttaaaa atattttttt catagtagtt ttattctatc ataaagaaaa
     9601 aaaatattct tgctttaata attcatctgt taagcttttt gaaaatatgg taaaataaag
     9661 tgagggaggt aactcatgtt tcgtagaaat aaattatttt tttggaccac agaaatttta
     9721 ctcttaacca tcatctttta cctatggaga cagatggggt ctttgattaa cccttttgtt
     9781 agcgtgctta atacaattat gattccattt ttattagggg gctttcttta ttatttgaca
     9841 aaccctattg ttactttctt aaataaagtc tgtaaactca atcgtttgct tggtatttta
     9901 attaccttgt gtactttggt ctggggaatg gtcataggtg ttgtctatct cttacctatt
     9961 ttgattaatc agttatctag tttgattata tctagtcaaa ctatttatag tcgagtacaa
    10021 gacttaatca tagacttatc taattatcct gcgctccaga atttggatgt agaagctaca
    10081 attcagcagt taaacttatc ctatgttgat attcttcaaa atatcctaaa tagcgtatca
    10141 aatagtgtgg ggagcgtctt gtcagctctt atcagtactg ttttgatttt gattatgact
    10201 ccagtttttt tggtttattt cttattagat ggacataaat tcttgcccat gcttgaaaga
    10261 acgattctaa agagggatcg cttgcatatt gcaggcttat taaagaattt aaatgcgacg
    10321 attgctcgct atattagtgg agtttcgatt gacgcaatca ttataggttg tttggcttat
    10381 attggctata gtattattgg tttaaaatat gctttagttt ttgccatttt ttctggtgta
    10441 gccaatttaa ttccttatgt ggggccaagt attggtttga ttcctatgat catcgcaaat
    10501 atattcactg atccccatag actgctgatt gcagtgattt atatgcttgt tgttcagcag
    10561 gtagatggca atatcttata tcctcgaatc gtaggaagtg ttatgaaggt tcatccaatc
    10621 acgattttag ttttactttt gttgtcaagc aatatctatg gtgtagttgg aatgattgtc
    10681 gcagtgccaa cctattctat cttgaaagaa atttctaagt tcttatcccg tttgtatgaa
    10741 aatcataaaa taatgaaaga acgagaaaga gaattagcta agtaaaagtc aggagaaccc
    10801 tgatttttct ttactggaag tggcctttag attagaagac tgaaaataag ttaaagtctt
    10861 aaactaattt tcacagctaa gaatagtaga agttaatctg ataaaaatcg aaaaaaccag
    10921 tggaattccg tgtcagggta agttccactg gttttcatag tctattaaag ttcgaatgaa
    10981 acctatttat agtatattga aactagaata gtacacctct aattctaaaa cattgttaga
    11041 aatcgatttg actgtcctaa tctattcgtc ctattcttat ttcattttac tatattttgg
    11101 tgcaataagt gaaaagtagt ccgaataata taaggattga ttttatagtt tttaaactca
    11161 aatgaattaa aataaagaga gtacgaaaat tctcatctga aagtatttta gaataattct
    11221 cttcgtgaat ttcttcaaaa cagatagctt catcttaggt atgtgttaat tggatttcgt
    11281 aagctctatt tacaatcgta aagttatgca ctgagaaagt tgtagttagt cttccagttt
    11341 gctaaatttt tcgaatagta tcttttttag gtatgtgatt tctttttgca tttttgagtt
    11401 agataaggta taatggtttt attgtctttt ggggtcgtta cggattcgac aggcattatg
    11461 aggcatattt tgcgactcgt gtggcgacgt aaacgctcag ttaaatataa ctgcaaaaaa
    11521 taacacttct tacgctctag ctgcttaaaa accagcaggc gtgacccgat ttggattgct
    11581 cgtgttcaat gacaggtctt attattagcg agatacgatt aagccttgtc tagcggcttg
    11641 ataagagatt gatagactcg cagtttctag acttgagtta tgtgtcgagg ggctgttaaa
    11701 ataatacata acctatggtt gtagacaaat atgttggcag gtgtttggac gtgggttcga
    11761 ctcccaccgg ctccattatt cctttgcatt ccttggtaaa acgttgttaa atcaacgttt
    11821 tttattttta tctttggtat tcctttgcat tcttttgcta aaaagggagt cacaaacaga
    11881 ccctatttta aaaaaggata gaaaaaagga tacaacattt gtcgcatcct aaaaataatc
    11941 ttttttccac ggaagacatg ggattcgaac ccacgcacgc tattacacgc ctaccgcgtt
    12001 tccaacacgg cctcttaagc ctcttgagta atcttccaat acttactcaa atagtctacc
    12061 ataaaggctc ttatcttgca ataaaaattc tagaaataag aaaaatgata gattttgaaa
    12121 gaaaatgata aaaaatgctt gacttcaaaa gaaagtatga tagaatgaat agtgtaaacg
    12181 ataacaggag gtgattcggt gttaaaaaca gagcggaagc aactgatttt agaggagtta
    12241 aatcaacatc atgtagtttc tctagaaaaa ttagttagtt tgctagaaac gtcagaatca
    12301 acggttcgaa gagacttgga tgagttggaa gcggaaaaca agcttcgtcg tgtgcatggt
    12361 ggagcagaac tcccccactc cttacaggaa gaagaaacca ttcaagaaaa atctgtcaaa
    12421 aaccttcaag aaaagaagtt gctggctcag aaagcagtct ctctcattaa agaaaaagat
    12481 gtcatcttta tcgatgctgg aacaacaact gcttttttga ttcatgaatt ggtcaataag
    12541 aatgttacag ttgtgaccaa ctccattcac catgccgctc agttggttga aaagcagatt
    12601 ccaactgtca tggttggagg aaacgtcaag acggcgacag atgctagtat cgggggcgtt
    12661 gctcttaacc agattaacca attgcacttt gaccgtgcct ttatcggaat gaatggtgtt
    12721 gacgatggct attatacgac tcctgatatg gaggagggag ctgtgaaaag agctattttg
    12781 gagaatgcca agcagaccta cgtcttggtg gattcgtcaa aaattggaca aacttgcttt
    12841 gccaaggtag ccccactcaa acgcgctatc gttatcacta gtcaagggca tgagctcttg
    12901 caggttatta aggagaaaac ggaggtaata gaagtatgat ttatacagtc acactcaatc
    12961 catccattga ctatatcgtt cgtttggacc aagtcaaagt tggtagtgta aatcgtatgg
    13021 acagtgatga taagtttgct ggtgggaaag gaatcaatgt cagccgtgtc ttgaaacgtt
    13081 tgaatatacc aaatacagcg acgggattta tcggtggctt tactggtaaa tttatcacag
    13141 atactttagc agaggaagaa atcgagacac gttttgtcca ggtggcagaa gatactcgta
    13201 tcaatgttaa aattaaagca gaccaagaaa cagaaatcaa cggaacgggt ccaactgttg
    13261 aactggttca gctagaagaa ttgaaagcta ttttatctag tctgacagca gaagatacag
    13321 ttgtctttgc aggttcaagt gctaaaaatc taggtaatgt tatctataag gatttgattt
    13381 ccttgacgcg ccagactggt gcgcaagtgg tctgtgactt tgaaggacag accttaattg
    13441 atagtttgga ctaccagcct cttcttgtaa aaccaaacaa tcatgaactt ggagcgattt
    13501 ttggggttaa actcgaaagt ttagatgaaa ttgagaaata cgctcgtgag ttactggcta
    13561 agggtgctca aaatgttatt atctctatgg ctggggacgg tgctcttctt gtcacatctg
    13621 agggagctta ctttgctaaa ccaatcaaag gaacagtcaa aaattcagtt ggggctggtg
    13681 attctatggt tgctggattc acaggtgaat ttgtcaaatc aaaagacgca gtagaagcct
    13741 tcaaatgggg agtggcttgc ggaacggcaa ctaccttctc agatgacttg gcaacggcag
    13801 aacttattaa agaaacatat ggaaaagttg aggtagaaaa acgatgaaaa ttcaagacct
    13861 attgagaaaa gatgtcatgt tgctagattt gcaggcaact gaaaaaacag ctgtcatcga
    13921 cgagatgatt aaaaatttga cagaccacgg ttatgtaaca gattttgaaa catttaaaga
    13981 aggaattttg gcgcgtgaag ctttgacttc tactggtttg ggtgatggaa tcgcaatgcc
    14041 tcacagcaaa aacgctgctg tcaaagaagc gacagttcta tttgctaagt caaataaggg
    14101 tgttgactac gagagcttgg atggacaagc aactgacctc ttcttcatga ttgcagctcc
    14161 agaaggtgcc aatgatactc acttggcagc cttggcagaa ttgtctcaat acttgatgaa
    14221 agacggtttt gcagacaaac ttcgtcaagc aacatctgca gaccaagtta tcgaactttt
    14281 tgaccaagct tcagaaaaaa ctgaggaact tgttcaagca cctgctaatg actctggtga
    14341 ctttatcgta gctgttacag cttgtacaac aggtattgcc cacacttaca tggcccaaga
    14401 agcccttcaa aaagtagctg ctgaaatggg ggttggtatc aaggtcgaaa ccaacggtgc
    14461 tagcggtgtt ggaaatcaac taactgcaga agatatccgt aaggctaaag ctattatcat
    14521 tgcagcagac aaggccgttg aaatggatcg atttgatgga aaaccattga tcaatcgtcc
    14581 agttgctgac ggtatccgta agacagaaga gctaattaac ttggctcttt caggagatac
    14641 tgaagtctac cgtgccgcta atggtgcaaa agctgcaaca gcctctaacg aaaaacaaag
    14701 ccttggtggt gccttctaca aacacttgat gagtggtgta tctcaaatgt taccattcgt
    14761 tatcggtggt ggtatcatga ttgcccttgc cttcttgatt gacggtgctt tgagtgttcc
    14821 aaatgaaaac cttggcaatc ttggttctta ccatgagtta gcttctatgt tcatgaaaat
    14881 tggtggagct gcctttggtt tgatgcttcc agtctttgcg ggttatgttg cctactctat
    14941 tgctgaaaaa ccaggtttgg tagcaggttt cgtggctggt gctattgcca aagaaggttt
    15001 tgcctttggt aaaattcctt atgccgcagg tggtgaagca acttcaactc ttgcaggtgt
    15061 ctcatctggt ttcctaggtg cccttgttgg tggatttatc gcaggtgcct tggttcttgc
    15121 catcaagaaa tacgttaaag ttcctcgttc actcgaaggt gctaaatcaa tccttctatt
    15181 gccacttctt ggaacaatct tgacaggatt tgttatgtta gctgtgaata tcccaatggc
    15241 tgcaatcaac actgctatga atgacttcct aggcagtctt ggaggaggtt cagctgtcct
    15301 tcttggtatc gtccttggtg gaatgatggc tgttgacatg ggtggaccag ttaataaagc
    15361 agcttatgtc tttggtacag gtacgcttgc agcaactgtt tcttcaggtg gttctgtagc
    15421 catggcagca gttatggctg gaggaatggt gccaccactt gcaatatttg tcgcaactct
    15481 tcttttcaaa gataaattta ctaaggaaga acgtaactct ggtttgacaa acatcatcat
    15541 gggcttgtca tttatcactg agggagcgat tccatttggt gccgctgacc cagctcgtgc
    15601 gattccaagc ttcatccttg gttcagcagt agcaggtgga ctcgttggtc ttactggtat
    15661 caaactcatg gcgccacacg gaggaatctt cgttatcgcc cttacttcaa atgctctcct
    15721 ttacctcgtt tctgtcttgg taggagcaat cgtaagtggt gtggtttatg gttacctacg
    15781 caaaccacaa gcataaaaaa tagaaaaatg aaaagattgg accgtttggt gcagtctttt
    15841 tctcttcccg aaatgcctgt gaaatatggt ataatagaag aatggcaaac aagaatacaa
    15901 gtacaacaag acggagaccg tctaaagcag aactggaaag aaaagaagcg attcaacgaa
    15961 tgttgatttc gttaggaatt gcgattttat tgattttcgc agccttcaaa ttaggggctg
    16021 caggtataac cctttataat ttaattcgct tgctagtggg tagcctagct tatctggcga
    16081 tattcggcct attaatctat ctcttctttt tcaagtggat acgaaaacag gaaggactct
    16141 tatctggctt tttcaccata tttgctggct tactcttgat ttttgaggcc tacttggttt
    16201 ggaaatatgg tttggacaag tccgttctaa aagggaccat ggctcaggtt gtgacagatc
    16261 tgactggttt tcgaacgact agctttgctg gagggggctt gatcggggtc gctctttata
    16321 ttccaacagc ctttctcttt tcaaatatcg gaacttactt tattggttct atcttgattt
    16381 tagtgggttc tctcctagtc agcccttggt ctgtttacga tattgctgaa tttttcagta
    16441 gaggctttgc caaatggtgg gaagggcacg agcgtcgaaa agaggaacgc tttgtcaaac
    16501 aagaagaaaa agctcgccaa aaggctgaga aagaggctag attagaacaa gaagagactg
    16561 aaaaagcctt actcgatttg cctcctgttg atatggaaac gggtgaaatt ctgacagagg
    16621 aagctgttca aaatcttcca cctattccag aagaaaagtg ggtggaacca gaaatcatcc
    16681 tgtctcaagc tgaacttaaa ttccctgaac aggaagatga ctcagatgac gaagatgttc
    16741 aggtcgattt ttcagccaaa gaagccctta aatacaaact tccaagctta caactctttg
    16801 caccagataa accaaaagat cagtctaaag agaagaaaat tgtcagagaa aatatcaaaa
    16861 tcttagaagc aacctttgct agctttggta ttaaggtaac agttgaacgg gccgaaattg
    16921 ggccatcagt gaccaagtat gaagtcaagc cggctgttgg tgtaagggtc aaccgcattt
    16981 ccaatctatc agatgacctc gctctagcct tggctgccaa agatgtccgg attgaagcac
    17041 caatccctgg gaaatcccta atcggaattg aagtgcccaa ctccgatatt gccactgtat
    17101 ctttccgaga actatgggaa caatcgcaaa cgaaagcaga aaatttcttg gaaattcctt
    17161 tagggaaggc tgttaatgga accgcaagag cttttgacct ttctaaaatg ccccacttgc
    17221 tagttgcagg ttcaacgggt tcagggaagt cagtagcagt taacggcatt attgctagca
    17281 ttctcatgaa ggcgagacca gatcaagtta aatttatgat ggtcgatccc aagatggttg
    17341 agttatctgt ttacaatgat attccccacc tcttgattcc agtcgtgacc aatccacgca
    17401 aagccagcaa ggctctgcaa aaggttgtgg atgaaatgga aaaccgttat gaactctttg
    17461 ccaaggtggg agttcggaat attgcaggtt ttaatgccaa ggtagaagag ttcaattccc
    17521 agtctgagta caagcaaatt ccgctaccat tcattgtcgt gattgtggat gagttggctg
    17581 acctcatgat ggtggccagc aaggaagtgg aagatgctat catccgtctt gggcagaagg
    17641 cgcgtgctgc aggtatccac atgattcttg caactcagcg tccatctgtt gatgtcatct
    17701 ctggtttgat taaggccaat gttccatctc gtgtagcatt tgcggtttca tcaggaacag
    17761 actcccgtac gattttggat gaaaatggag cagaaaaact tcttggtcga ggagacatgc
    17821 tctttaaacc gattgatgaa aatcatccag ttcgtctcca aggctccttt atctcggatg
    17881 acgatgttga gcgcattgtg aacttcatca agactcaggc agatgcagac tacgatgaga
    17941 gttttgatcc aggtgaggtt tctgaaaatg aaggagaatt ttcggatgga gatgctggtg
    18001 gtgatccgct ttttgaagaa gctaagtctt tggttatcga aacacagaaa gccagtgcat
    18061 ccatgattca gcgtcgtttg tcagttggat ttaaccgtgc gacccgtctc atggaagagc
    18121 ttgagatggc aggtgtcatt ggtccagctg aaggtaccaa gccaagaaaa gtattgcagc
    18181 aataaaaaat agcttctttc caaggttgga aggagctatt ttactggcta ttgattactt
    18241 ttattttctg aagttggagt attgggctgt ttttcatttt cagtggcagg tttacttgta
    18301 gcaggtgtag tagagtcctg agttgctgtt ttctgatctt cttttttctc ttccttgacg
    18361 ctagattttg gcgtttcttc ttgttgtgtt ttttcttgag aagtgttatt ttccttattt
    18421 ggagtagtat tttcctgagg ggattctttt tgaatttctt tgacaaaggt tgtcgtctgg
    18481 cttgtcgtag gttctttttt agtattttta ttattattat ccaaggcgtt catgatcgtg
    18541 atacccgctg taatcaaacc aaggatacta ccgatagtag taatggtttt ttgaaaaaca
    18601 gtaaagcctt ttttgatatg ttctgttttc ggttttgaag ttctacgata gttagacata
    18661 cattctctcc tttgattatg atttattata ctctgtttct ttaaaaaaat cttaaaaaaa
    18721 gagaaattgc cctttcttgt cgcaagctcc gtttcatgat acaatagagg gagtgatttt
    18781 agaaagcgtg agaaacatga tttactttga taattcagcg acgaccaagc cttatcctga
    18841 agcccttgaa acctatatgc aggtcgcttc aaaaatttta ggaaacccat ctagtctcca
    18901 tcgtttggga gaccaagcaa cacgaatctt agatgcttct cgccaacaga ttgcagattt
    18961 aatcggtaag aaaatcgatg aaatcttctt tacctctggt ggaacagaag gggataactg
    19021 ggttatcaag ggtgtggcct ttgaaaaagc tcagtttggc aagcacatca ttgtttcagc
    19081 cattgaacat ccagcagtca aagagtcagc cctctggttg aaaagtcaag gatttgaagt
    19141 ggattttgct ccagttgata agaaaggctt ggtcgatgtt gaggcgttag caggtttgat
    19201 acggcctgat acaatcctcg tttccatcat ggctgtgaac aatgaaatcg gctctatcca
    19261 acctattgag gctatttcag aattcttggc agacaagccg actatttcct tccacgttga
    19321 tgcggttcag gcgcttgcca aaattccgac tgaaaagtat ctgacagaac gggtggattg
    19381 cgcgaccttc tcgagtcata aatttcatgg tgtccgtggt gttggctttg tctatatcaa
    19441 atctggcaag aagattacac ctcttcttac aggtggtggc caggagcgag attatcgttc
    19501 gacaactgaa aatgtggcag ggattgcagc gacagccaag gctctccgtt tatctatgga
    19561 aaagctagat atctttagga gcaagactgg gcagatgaag gcagtgattc accaagctct
    19621 tctgaactat ccggatattt ttgtcttttc agatgaggaa gactttgcac ctcatattct
    19681 gacttttgga atcaaaggtg ttcgaggtga agtcatcgtt cacgcctttg aagactatga
    19741 tattttcatc tcaacaacct cagcttgttc atctaaggca ggaaaaccag ccggtacctt
    19801 gattgccatg ggagtggaca aagataaggc caagtcagct gtgcgtctta gcctagactt
    19861 ggaaaatgat atgagtcagg tcgagcagtt tttgaccaag ttaaaattga tttacaatca
    19921 aactagaaaa gtaagatagg agcattcatg cagtattcag aaattatgat tcgctacgga
    19981 gagttgtcaa ccaagggtaa aaaccgtatg cgtttcatca ataaacttcg taataatatt
    20041 tcggacgttt tgtctatcta tacccaagtt aaggtaacag cagatcgcga ccgtgcccac
    20101 gcttacctca atggagctga ttacacagca gttgcagaat ctctcaaaca agtttttgga
    20161 attcaaaact tttctcctgt ttataaggtt gaaaaatctg tagaagtttt gaagtcttct
    20221 gtccaagaga ttatgcggga catctacaag gaaggtatga cctttaagat ttctagcaag
    20281 cgtagcgacc acaactttga acttgatagt cgtgaactca accaaacact tggaggggct
    20341 gtattcgaag ccattccaaa tgtgcaagtt caaatgaaaa gtcctgacat caatcttcag
    20401 gtggagattc gtgaagaagc agcctatctt tcttatgaaa ccattcgtgg ggctggtggt
    20461 ttgccagttg gaacttcagg taaagggatg ctcatgttgt caggagggat tgactcacct
    20521 gtagcaggtt atcttgctct taagcgtggg gtggatatcg aggcagttca ctttgctagt
    20581 ccaccatata ctagtcctgg tgccctcaag aaagcgcagg acttgacccg taaattgacc
    20641 aagtttggcg gaaatatcca gtttatagag gtgcctttca cagagattca agaggaaatc
    20701 aaagccaaag cgccagaagc ttatttgatg actctaactc gtcgctttat gatgcggatt
    20761 actgaccgta ttcgtgaggt acgaaatggt ttggttatca tcaatgggga aagtctaggt
    20821 caagtagcca gccaaaccct tgaaagtatg aaggctatca atgctgttac caacactccc
    20881 atcattcgtc ctgtggttac catggacaag ttggaaatca ttgacatcgc ccaggaaatc
    20941 gatacctttg acatttcaat ccaaccgttt gaagactgtt gtaccatttt tgcaccagat
    21001 cgtccaaaaa caaatcctaa aattaagaat gcggagcagt acgaagcgcg tatggatgtt
    21061 gaaggcttgg ttgagcgagc agtggctgga atcatgatta ctgaaatcac acctcaagcc
    21121 gaaaaagatg aagttgatga cttgattgat aatctactct aattcagaaa atccaaaaga
    21181 atagcgaaaa tcagtaaaaa aagttagttt tttctctaaa aacaggtaaa aaactaactt
    21241 tttttatttt tatgatataa tgatataaa
//
LOCUS       DBERXF010000040        19927 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.40, whole genome shotgun sequence.
ACCESSION   DBERXF010000040 DBERXF010000000
VERSION     DBERXF010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19927
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.40"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            240..1685
                     /gene="cps4A"
                     /locus_tag="ACL8JK_001662"
     CDS             240..1685
                     /gene="cps4A"
                     /locus_tag="ACL8JK_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HGS1786514.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVAAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGIDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIIDSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            1687..2418
                     /gene="cps4B"
                     /locus_tag="ACL8JK_001663"
     CDS             1687..2418
                     /gene="cps4B"
                     /locus_tag="ACL8JK_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HGS1786515.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYNALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            2427..3119
                     /gene="cpsC"
                     /locus_tag="ACL8JK_001664"
     CDS             2427..3119
                     /gene="cpsC"
                     /locus_tag="ACL8JK_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HGS1786516.1"
                     /translation="MKEQNTLEIDVLQLFRVLWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQGEKSGLTSQDLQAGSYLVKDYREIILSQDVLEEVVSDLKLD
                     LTPKGLANKIKVTVPADTRIVSVSVNDRVPEEASRIANSLREVAAKKIISITRVSDVT
                     TLEEARPAISPSSPNLKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIEDTLQMT
                     LLGVVPNLNKLK"
     gene            3129..3812
                     /gene="cpsD"
                     /locus_tag="ACL8JK_001665"
     CDS             3129..3812
                     /gene="cpsD"
                     /locus_tag="ACL8JK_001665"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HGS1786517.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVS
                     PGEGKTTTSVNIAWSFARAGYKTLLIDGDIRNSVISGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTATGEANKRDVQKAQQQLKQTGKLFLGVVFNKLDISVDKYGVY
                     GFYGNYGKK"
     gene            3828..5195
                     /locus_tag="ACL8JK_001666"
     CDS             3828..5195
                     /locus_tag="ACL8JK_001666"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGS1786518.1"
                     /translation="MDEKGLKIFLAVLQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFEKMG
                     MDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVISKRILDICGATIGLIL
                     FAIVSLVLVPLIRKDGGPAIFAQTRIGKNGRHFTFYKFRSMQIDAEAIKEQLMDQNTM
                     QGGMFKIDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            5226..6398
                     /gene="cps2T"
                     /locus_tag="ACL8JK_001667"
                     /gene_synonym="wchF"
     CDS             5226..6398
                     /gene="cps2T"
                     /locus_tag="ACL8JK_001667"
                     /gene_synonym="wchF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta 1-4 rhamnosyltransferase Cps2T"
                     /protein_id="HGS1786519.1"
                     /translation="MKKSVYIIGSKGIPAKYGGFETFVEKLTAFQQDKTIQYYVACMR
                     ENSAKSGTTEDVFEHNGAICYNVDVPNIGPARAIVYDIAAINRAIKIAKENKDEDPIF
                     YILACRIGPFIHGIKKKIQEIGGTLLVNPDGHEWLRAKWSAPVRRYWKISEGLMVKHA
                     DLLVCDSKNIEKYIQEDYIQYQPKTTYIAYGTDTTRSTLNSSDEKVRAWFKEKNVSEN
                     EYYLVVGRFVPENNYESMIRGFLASSSKKDFVLITNVEQNKFYNQLLASTGFDKDPRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     QSAIYWKKDELSQVIEKVEQFDAKIIDELDRQSNQRIVDFFTWEKIVTDYEKLFKK"
     gene            6395..7666
                     /locus_tag="ACL8JK_001668"
     CDS             6395..7666
                     /locus_tag="ACL8JK_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS1786520.1"
                     /translation="MKILHYTLGFQPQRTGGLVKYAEDLMLEQIAQGYQVAALYPGRI
                     KFFSKKIEIIKETSRQFECYELLNSLPMALFGGISDPTAFLTPCDKNVYRTFLEKVQP
                     DIIHIHSFMGLHKEFLEIAKSLNIRVVFTSHDYYGLAPVPHFYFNGVDYSDKSTNLTW
                     NIMSSNALSVKKLRLFQVSFYPTIRKLLKLLGKNPKSKKNLVIRDVIEEQDYSELRYY
                     YNEMFHLIDGYLFNSRLAKKVYEINEIKSANSIVLSITNSSINHHQRLTTTNNKIRVA
                     YIGPDEEYKGYFDFVDFVETLDRESYEVATYGHLPNEECPSFIEQKGYFTKEMIDSVY
                     ENIDILIVPSKWKETFGLITVEALSYGVNVFVSENVGSKDLLPESHVFKNQNDLIVKF
                     LKNDIENTKLKTLDEHSIEVIQYYERVINDS"
     gene            7656..8342
                     /locus_tag="ACL8JK_001669"
     CDS             7656..8342
                     /locus_tag="ACL8JK_001669"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HGS1786521.1"
                     /translation="MIVKSFIKKITGKTVDIHPDVPLSYILQRGINYSFGLFRGVVRG
                     IGFGQNDKRLFIGQGVSILAKRKLFVGKNVRIGKKVSIDALSKEGIHFADNVKIGDYS
                     QIIGTGSIKNMGIGLKIGKNSSFSEYSLFGSAGGITIGDNVIAGQNVRFHAENHNYSD
                     LDKLIVEQGVSRKGISVGDNCWIGAGSVFLDGSSIGSGCVVAANSVITKNFPDNVIVA
                     GVPAKIIKMK"
     gene            8354..9259
                     /locus_tag="ACL8JK_001670"
     CDS             8354..9259
                     /locus_tag="ACL8JK_001670"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012745.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS1786522.1"
                     /translation="MRKEIKAVYAILNYNTWEDTARLAQKVATFQHIQSVIIVDNLST
                     DDSYHYLKRLEGEKISVYQTQRNGGYSVGNNFAARKAYNMGVDILFISNPDVDIDEKD
                     SLMIAQNLYKNSSYALLSGIEYNAMKEIDLPIVWHENSYYDDLLDCLFLTRKWRRKKE
                     DINLSMIKSSIIDVDLVKGSFFAVRLSDFHDVGYFDESVFLFCEERILAKKLQKVNKK
                     IGILPEAKYYHNHSTSINERYKKKKEQINLLYKSRYYYNVKYNNISFVKKLCLKSVMM
                     LSILEYIILDMMNLLYTKTNYKKIQ"
     gene            complement(9360..9722)
                     /locus_tag="ACL8JK_001671"
                     /pseudo
     CDS             complement(9360..9722)
                     /locus_tag="ACL8JK_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001857010.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            9949..11211
                     /locus_tag="ACL8JK_001672"
     CDS             9949..11211
                     /locus_tag="ACL8JK_001672"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786523.1"
                     /translation="MSKLILNLKLNSFLFVIILLLVVVTPTHTLIFDALIPTKIDNLW
                     REFLLVISFLCILKINAGKIKIGKLGGPIIVMGGIGLVYTICSDRPFTALNLFRIYMF
                     PAVIYFIIINCNFRKERLLILKQAHVYTACILALWGIFQAWVLKDQFLIKIGYPSQGN
                     FLKSTAFYIGGFFGQQRVTSTFSAPNLAGVYFGISLIILLSIFDTIKSNRLVLFSIVA
                     AFVLTFSRSAIISTLVGIVFFQRKKLFSTTKINVMTLVIFPLIFLIVLVIFYLYPENV
                     IINMLYSSYSSTLNLTDSSAVKHLEDLWLPLLKVIDYPLGLGFGNNGPIVLSLYHSAN
                     LVESSIYLLAYDFGILGMFIYLFPYFYTIFVYKKYLLSGAICCLVLITYLFLPNVENF
                     EIIFFIYLFIGMDELALYTKGMNVHEID"
     gene            11198..12358
                     /locus_tag="ACL8JK_001673"
     CDS             11198..12358
                     /locus_tag="ACL8JK_001673"
                     /inference="COORDINATES: protein motif:HMM:NF016357.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HGS1786524.1"
                     /translation="MKLIKLLKKYINLYISSSVPKTNKLLIFGSWLGEKYADNPRYLF
                     EYVIKNRPDLKAIWITSNQDVFKELQKKQYLVMMAEAPETRKIVKKAKYIFTATGIFD
                     IGEQNANFVGGAYLINLWHGIPLKKIMYDDKHSALHKRSKLVTWVEKIPLRNYFVIST
                     STAITQIYQSAFRVKKSNILELGQPRNDYFYDKSNPVSSLIQELKSKNIILYMPTHRN
                     EGKKQIDLDKLMDLEHLNNWCEETKSIFVIKKHFYHSKEKTIDKKYSSIIDVTNEKVD
                     VQELLKCSNVLITDYSSCYIDYLLLNRPIIFFNYDYDDYLRVDRSLYFPYENVTPGEK
                     CQNFDELLVTLQNLYVGKDDYREERENIKTFFYSSETQKSVSEKIINHVLNL"
     gene            12376..13815
                     /locus_tag="ACL8JK_001674"
     CDS             12376..13815
                     /locus_tag="ACL8JK_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGS1786525.1"
                     /translation="MKKILNKYYSLSNPVKASIWFTICNVLQKGISMITVPVFTRVLT
                     TEQYGVYSVYQSWYSIIGVFATLNLYYGVFNNGMIKYEKDKNVFTSSMQGLTTTVTAI
                     FLLIYLIGIDFWNSLLGLPTLLILVMFFDLFFTPAYSFWVARQRFEYKYRNLVFITFI
                     IAIGSPIIGISAVVLSTYKAEARVISFVLVQSCIGLYFYILNLYRGKHFFCKKYWLYA
                     LNFNLPLIPHYLSQSVLNQSDRIMINSMVGMGEAAIYSVAYSISILMLLVTSAINSSF
                     IPYTYKCIRDKKYTELGKSANLLITLVGIGSILTISLGPEIIQLFAPKQYYEAIWIIP
                     PVALSVYFMFLYPIFGNIEFYFEANHFVMWASIGGAIMNIFLNFIFLKHFGYIAAGYT
                     TLFCYILFALGHYIFMRRVLYQNLSGIQIYNSRYLLFFSILLIILMLLIVIIYPFILI
                     RYLTISLILGGCFLKRKKIMSSIAIIKQQ"
     gene            13825..14640
                     /locus_tag="ACL8JK_001675"
     CDS             13825..14640
                     /locus_tag="ACL8JK_001675"
                     /inference="COORDINATES: protein motif:HMM:NF016852.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS1786526.1"
                     /translation="MTETNKQLHETLIEILDFVKEICEKHELTYFLVFGTALGAKRHC
                     GFIPWDDDVDIALPREHYNIFIDALSETDQSIFSLQNEDNEPNYFLPFAKLRKNNTIF
                     IEKILDVEYENNGIYIDIFPLDFVENPDSFNFKIRRTTFNYIKHILKFSSCRSFYKNK
                     YSNVRYLIENIMSIPTLFFSNRRLLFLANSLISSTTKADFIGQYDQKSNKRAIMPSNY
                     YFPPRSAVFEGKTYSVPAKLEDYLKCFYGSDYMELPPIEKRVTHQPITLRFEK"
     gene            14668..15060
                     /gene="tagD"
                     /locus_tag="ACL8JK_001676"
     CDS             14668..15060
                     /gene="tagD"
                     /locus_tag="ACL8JK_001676"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0047348 - glycerol-3-phosphate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HGS1786527.1"
                     /translation="MKRVITYGTFDLLHHGHINLLRRAKELGDYLVVVVSSDEFNLIE
                     KNKVCYFNYEHRKSLVEAIRYVDLVIPETSWEQKRSDVKEYHIDTFVMGDDWIGEFDY
                     LKEEGVEVVYLPRTKEISTTKIKKDLSM"
     gene            15217..16086
                     /gene="rfbA"
                     /locus_tag="ACL8JK_001677"
     CDS             15217..16086
                     /gene="rfbA"
                     /locus_tag="ACL8JK_001677"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HGS1786528.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGLKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKN
                     EYGQYLLRLIGEA"
     gene            16087..16683
                     /locus_tag="ACL8JK_001678"
     CDS             16087..16683
                     /locus_tag="ACL8JK_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HGS1786529.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDLE"
     gene            16693..17742
                     /gene="rfbB"
                     /locus_tag="ACL8JK_001679"
     CDS             16693..17742
                     /gene="rfbB"
                     /locus_tag="ACL8JK_001679"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HGS1786530.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            17808..18659
                     /gene="rfbD"
                     /locus_tag="ACL8JK_001680"
     CDS             17808..18659
                     /gene="rfbD"
                     /locus_tag="ACL8JK_001680"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HGS1786531.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            18756..19920
                     /locus_tag="ACL8JK_001681"
                     /pseudo
     CDS             18756..19920
                     /locus_tag="ACL8JK_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251597.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6537 a         2976 c         3966 g         6448 t
ORIGIN      
        1 cacattgtgt actatagtag attgaaacta gaatagtaca cctctgcttc taaaatattg
       61 ttagaaatcg atttgactgt cctgatcgat ttgtcatgtt cttatttcat tttactatat
      121 ttttggttcg cgggaagtct actaagatac ttaaagatgc agatagtgaa aataaaggtg
      181 tagacattac cgtaaaaaag tgatataatc gtatgatgtt caatgtatag gtgttaatca
      241 tgagtagacg ttttaaaaaa tcaggttcac agaaagtgaa gcgaagtgtt aatatagttt
      301 tgttgactat ttatttattg ttagtttgtt ttttattgtt cttaatcttt aagtacaata
      361 tccttgcttt tagatatctt aatctagtgg taactgcgtt agtcctacta gttgccttgg
      421 tagggctact cttgattatc tataaaaaag ctgaaaaatt tactattttt ctgttggtgt
      481 tctctatcct tgtcagctct gtgtcgctct ttgcagtaca gcagtttgtt ggactgacca
      541 atcgtttaaa tgcgacttct aattactcag aatattcaat cagtgtcgct gttttagcag
      601 atagtgagat cgaaaatgtt acgcaactga cgagtgtggc agcaccgact gggactgata
      661 atgaaaatat tcaaaaacta ctagctgata tcaagtcaag tcagaatacc gatttgacgg
      721 tcaaccagag ttcgtcttac ttggcagctt acaagagttt gattgcaggg gagactaagg
      781 ccattgtcct aaatagtgtc tttgaaaata tcatcgagtc agagtatcca gactacgcat
      841 cgaagataaa gaagatttat accaagggat tcactaaaaa agtagaagct cctaagacgt
      901 ctaagaatca gtctttcaat atctatgtta gtggaattga cacctatggt cctattagtt
      961 cggtgtcgcg atcagatgtc aatatcctga tgactgtcaa tcgagatacc aagaaaatcc
     1021 tcttgaccac aacaccacgt gatgcctatg taccaatcgc agatggtgga aataatcaaa
     1081 aagataaatt aacccatgcg ggcatttatg gagttgattc gtccattcac accttagaaa
     1141 atctctatgg agtggatatc aattactatg tgcgattgaa cttcacttct ttcttgaaaa
     1201 tgattgactt attgggaggg atagatgttc ataatgatca agagttttca gctctacatg
     1261 ggaagttcca tttcccagta gggaatgtcc atctagactc tgagcaagct ttaggttttg
     1321 ttcgtgagcg ctactcccta gcagatggcg atcgtgaccg tggtcgcaac caacaaaagg
     1381 tgattgtggc tatccttcaa aaattaacgt caaccgaagc actgaaaaat tatagtacga
     1441 tcattgatag cttgcaagat tctatccaaa caaatatgcc acttgagacc atgataaatt
     1501 tggtcaatgc tcagttagaa agtggtggaa cttacaaagt gaattcgcaa gacttgaaag
     1561 gtacaggtcg gatggatctt ccttcttatg caatgccaga cagtaacctc tatgtgatgg
     1621 aaatagatga tagtagttta gctgtagtta aagcagctat acaggatgtg atggagggta
     1681 gatgaaatga tagacatcca ttcgcatatc gtttttgatg tagatgacgg tcccaaatca
     1741 agagaggaaa gcaaggctct cttggcagaa gcctacagac agggggtgcg aaccattgtc
     1801 tctacctctc accgtcgcaa gggcatgttt gaaactccgg aagagaagat agcagaaaac
     1861 tttcttcagg ttcgggaaat tgcaaaagaa gtagcagatg atttagtcat tgcttatggc
     1921 gcagagatat actatactct ggatgctcta gaaaagctag aaaaaaaaga aattcctacc
     1981 cttaatgata gtcgttatgc cttgattgag tttagcatgc atacttccta tcgtcagatt
     2041 catacgggat tgagcaatat tttgatgttg ggaatcacgc cagtaattgc tcatattgaa
     2101 cgttataatg ctttagagaa taacgaaaaa cgtgttcgtg aactgattga tatggggtgc
     2161 tatactcaga taaatagtta tcatgtttca aaacctaagt tctttggtga aaaatataaa
     2221 ttcatgaaaa agagagctcg gtattttttg gaacgtgatt tagttcatgt agttgcaagt
     2281 gacatgcaca atttagacag tagacctcca tatatgcaac aggcatatga tatcattgct
     2341 aagaaatatg gagcgaaaaa agcgaaagaa ctttttgtag ataatcccag aaaaattata
     2401 atggatcaat taatttagga gaaaatatga aggaacaaaa cactttggaa atcgatgtat
     2461 tgcaactatt cagagtttta tggaaaagga agttggtcat tttattagtg gcaattataa
     2521 cttcttcagt tgcttttgcc tacagtactt ttgttatcaa acctgagttt actagtacga
     2581 ctcggattta tgtagttaac cgtaatcagg gagagaagtc tggtttaacc agtcaagact
     2641 tgcaggcagg atcgtacttg gttaaagact atcgtgaaat tatcctatcg caggatgttt
     2701 tggaggaagt tgtttctgat ttgaaactag atttgacgcc aaaaggtttg gctaataaaa
     2761 tcaaagtaac agtaccagct gatacccgta ttgtctctgt ttcagttaat gatcgagttc
     2821 ctgaagaggc aagccgtatc gctaactctt tgagagaagt agctgctaaa aaaattatca
     2881 gtattactcg tgtttctgat gtgacaacac tggaggaggc aagaccggcg atatcaccgt
     2941 cttcgccaaa tcttaaacgc aatacactaa ttggtttttt ggcaggggtg attggaacta
     3001 gtgttatagt tcttcttctt gaacttttgg acactcgtgt gaaacgtccg gaagatatcg
     3061 aagatacact acagatgaca cttttgggag ttgtaccaaa cttgaataag ttgaaatagg
     3121 agagagagat gccgacatta gaaatagcac aaaaaaaact ggagttcatt aagaaggcag
     3181 aagaatatta caatgccttg tgtacaaata tacagttgag cggagataaa ctaaaagtaa
     3241 tttccgttac ttctgttagc ccgggggaag gaaaaacaac tacttccgta aatatagcat
     3301 ggtcgtttgc gcgtgcaggc tataaaactc ttttgatcga tggcgatatt cgaaattcag
     3361 tcatatcagg attttttaaa tctcgtgaaa aaattacagg gctaacagaa tttttatctg
     3421 ggacagctga tttatctcac ggtttatgtg atacaaatat tgaaaattta tttgtagttc
     3481 aatcgggctc tgtatcacca aaccctacag ccttgttaca aagtaaaaat tttaatgata
     3541 tgattgaaac attgcgtaaa tattttgatt atatcattgt tgatacagca cctattggaa
     3601 ttgttattga tgcggcaatt atcactcaaa agtgtgatgc gtccatcttg gtaacagcaa
     3661 caggtgaggc gaataaacgt gatgtccaaa aagcgcaaca acaattaaaa caaacaggga
     3721 aactgttcct aggagttgtt tttaataaat tagatatctc ggttgataag tatggagttt
     3781 acggtttcta tggaaattat ggtaaaaaat aacttaggaa agattttatg gatgaaaaag
     3841 gattgaaaat ttttctggca gtattacaga gtattattgt cattttattg gtttattttc
     3901 ttagctttgt tagagagaca gaacttgaac gttcttcgat ggttatacta taccttctcc
     3961 acttttttgt attctatttt agttcctatg gtaacaattt ttttaaaaga gggtacctag
     4021 ttgagtttaa tagtactata agatatattt ttttctttgc aatagctata agtgtattaa
     4081 acttttttat agcggaacgg tttagcatct ctagaagagg aatggtatac ttcttaactt
     4141 tagaaggaat atccttatac ttgttaaatt tcttagtaaa gaaatattgg aagcatgtgt
     4201 tttttaatct aaaaaatagc aagaaaattt tactgttaac agtaacgaaa aatatggaaa
     4261 aagttcttga taaattgcta gaatctgatg aactttcatg gaaattggta gcagtaagtg
     4321 ttttggataa atctgatttt caacatgata aaatacctgt aattgaaaag gaaaaaatta
     4381 ttgaatttgc aacgcatgaa gttgtggatg aggtgtttgt caatcttcca ggagagagct
     4441 acgatattgg agaaattatc tctaggtttg agaaaatggg gatggatgta actgtaaatc
     4501 ttaaagcatt tgataagaat ttgggtcgca ataaacaaat tcatgagatg gtaggattga
     4561 atgtagtcac tttctctaca aatttttata aaactagtca tgtgatttca aagagaattc
     4621 tcgatatttg tggtgccact attggcctta ttctttttgc tatagttagt ctagttttag
     4681 ttccattgat tcgtaaagat ggcggaccag ctatttttgc tcaaactcgt atagggaaaa
     4741 atggtcgaca ttttaccttt tataaattcc gttcgatgca gatcgatgct gaagctatca
     4801 aagaacagtt gatggatcaa aatacgatgc aaggtggtat gtttaagata gacaatgatc
     4861 ctcgtgttac aaaaattggt cgctttattc gtaaaaccag tttagatgag ttaccccagt
     4921 tttggaatgt ctttatagga gatatgagtt tggtgggaac acgtccacct acagtagacg
     4981 agtatgatca gtatactcca gaacagaaac gtcgactcag ctttaaaccc ggtattacag
     5041 gtttatggca ggttagcggc cgtagtaaaa taaccgattt tgacgatgtt gtaaaattag
     5101 atgtggctta tattgataat tggacaatct ggaaagatat tgaaattttg cttaaaactg
     5161 ttaaagttgt atttatgaga gatggagcga agtaatttct gtatatccat catattagga
     5221 gagaaatgaa aaagtcagtt tatatcattg gttcaaaagg aattcctgct aagtatggag
     5281 gatttgaaac ttttgttgaa aaattaacag ccttccaaca agataagact atccaatatt
     5341 atgtggcttg tatgcgtgaa aactctgcaa aatcagggac tactgaggat gtttttgaac
     5401 ataatggtgc tatctgttat aacgtcgatg ttcctaatat tggtccagcg cgagccatag
     5461 tatatgatat cgcggcaatt aacagagcta ttaaaattgc caaagaaaat aaggatgaag
     5521 atccaatctt ctatattcta gcttgtcgaa tcggtccgtt catccatgga attaagaaaa
     5581 aaatccagga gataggtggg actcttctag ttaatccaga tggtcacgag tggttacgag
     5641 ctaagtggag cgctccagtt cgtcgttatt ggaaaatttc cgaaggtctt atggtcaaac
     5701 atgcagatct tttagtgtgt gatagtaaga atattgaaaa atatatccaa gaagattata
     5761 tacagtatca acctaagaca acctatatcg cttatgggac agatacaaca cgctccacat
     5821 taaatagcag tgatgaaaaa gtgcgtgctt ggttcaagga gaaaaatgtt tctgaaaacg
     5881 agtattacct agttgtagga cgttttgttc cagaaaataa ttatgagtct atgatacgtg
     5941 gtttcttggc gtctagctct aagaaggatt ttgtcctaat cacaaatgta gaacagaata
     6001 aattttataa tcagctatta gcaagtactg gatttgataa agatccacga gtgaaatttg
     6061 ttggaacagt ctacgaccaa gaacttctga agtatattcg agaaaatgct tttgcttact
     6121 tccacggaca tgaagttggt ggaacaaatc cttcgttact tgaagcatta gcatccacaa
     6181 agttaaactt actactcgat gttggtttta accgcgaagt tggggagcaa agtgcgatct
     6241 attggaaaaa agatgagctt tcccaagtaa tcgagaaagt tgaacaattt gatgcaaaaa
     6301 ttattgatga gttagataga caatcaaatc agagaattgt ggattttttc acttgggaaa
     6361 agattgtcac agactacgag aaattattta aaaaatgaaa atattacatt atactttagg
     6421 atttcaaccc cagcgaacag gtggtttggt taaatatgct gaggatttaa tgctagagca
     6481 aattgctcaa ggttatcaag tggctgccct atatccagga agaattaagt tcttttcaaa
     6541 aaaaatagaa ataattaaag agacgtcaag acagtttgag tgttatgagc tgcttaatag
     6601 cttacctatg gctttatttg gagggatatc cgatccaact gctttcctga caccttgtga
     6661 caaaaatgtt tatcgtactt ttttagaaaa agtacaaccc gacattatac atattcactc
     6721 gtttatggga ttgcataaag aattcctcga aattgctaaa agcttgaata ttagagtggt
     6781 ttttacgagc catgattatt atggattagc acccgtacct catttctatt ttaatggggt
     6841 ggattatagt gataaaagta caaacttaac atggaatatt atgtcttcca atgctttaag
     6901 tgtgaaaaaa ctaagacttt ttcaggtttc attttatcct actattcgta aacttttgaa
     6961 actattaggg aaaaatccaa aatctaaaaa gaatttagtt attcgagatg ttattgagga
     7021 gcaagattat agtgagcttc gatactatta taatgagatg tttcacttaa tagatggtta
     7081 tttgtttaat agtagacttg caaagaaggt atatgagata aatgagatta agtcagctaa
     7141 tagtatagta ttatctataa caaatagttc aattaatcat catcagagat tgacaactac
     7201 aaataataaa attagagttg cttatattgg tccagatgaa gaatataaag gatattttga
     7261 ttttgttgac tttgttgaaa ctttagatcg agagtcctat gaagtggcaa cttatggcca
     7321 tttaccaaat gaagagtgtc cttcattcat tgaacaaaaa ggatatttta ctaaggaaat
     7381 gattgacagt gtctatgaaa atattgatat tcttattgtt ccaagtaagt ggaaggaaac
     7441 atttggattg ataacagtag aagcattatc ctatggggta aatgttttcg tgagtgaaaa
     7501 tgttgggtca aaagacttac ttccagaatc gcatgttttt aaaaatcaga atgatttaat
     7561 agttaaattt ttaaaaaatg atatagaaaa tacaaaattg aaaactttag atgaacactc
     7621 gatagaagtg attcagtatt atgaaagagt gataaatgat agttaagagt ttcataaaaa
     7681 agattactgg aaaaacagta gacattcatc cagatgtacc tttgtcgtat atactacaaa
     7741 gaggtataaa ctatagtttc ggactctttc gtggggttgt acgtggaatc ggatttggtc
     7801 aaaacgacaa acgtttattc attggacaag gagtttctat cttagcaaag cgtaaattat
     7861 ttgttggaaa aaatgttcga attggtaaaa aggtgtctat agatgcactg tcaaaagaag
     7921 gaatccattt tgcagataat gtaaagattg gagattattc tcaaattatt ggcacaggtt
     7981 ctataaaaaa tatggggatt ggcttgaaaa tcggtaagaa ctcatctttt tcagaatata
     8041 gtttatttgg ttctgctgga ggtatcacaa ttggtgataa tgttatcgca ggtcagaatg
     8101 ttcgttttca tgctgaaaat cataattata gtgatttaga taaactcatt gttgaacaag
     8161 gggtatctcg aaagggaatt tcagtaggtg ataattgttg gattggtgct ggatctgttt
     8221 ttttggatgg gtccagcatt ggttcaggtt gtgttgtagc tgcaaattct gtaattacga
     8281 aaaactttcc agataacgtt attgttgctg gagtaccagc taaaattata aaaatgaaat
     8341 gataggatgt taaatgagga aagaaattaa agctgtttat gcgatattaa attacaatac
     8401 ttgggaagat actgcgcgtt tagcacagaa agttgcaaca tttcagcata ttcaatctgt
     8461 gataatagtg gataatctat caacagatga ttcataccat tatttaaaaa gacttgaggg
     8521 agagaaaatt tcagtttatc aaacacaaag aaatggtgga tattctgttg gaaataattt
     8581 tgcagcacga aaagcttata atatgggagt tgatattctt ttcatttcaa atccagacgt
     8641 tgatattgat gaaaaagatt ccttgatgat tgcacaaaat ttgtataaaa atagttcata
     8701 tgcactgcta tcaggtatag aatataatgc tatgaaggag atagatttgc caattgtctg
     8761 gcatgaaaat tcctattacg atgacttact tgattgtttg tttttaacca gaaaatggcg
     8821 aagaaaaaaa gaagatatca atttgtcaat gattaaatca tctataatag atgtagatct
     8881 tgttaaagga tcgttttttg ctgtaagact gtctgatttt catgatgttg gttattttga
     8941 tgaatctgta tttctttttt gtgaagagag aatattagct aaaaagttac aaaaagtaaa
     9001 taaaaaaata ggtattctgc ctgaagcgaa atattaccac aatcattcaa cttctataaa
     9061 tgagagatat aaaaagaaaa aagaacagat taatttatta tataagtctc gatactacta
     9121 taatgtaaag tataataata ttagttttgt caaaaaacta tgtttaaaat ctgtcatgat
     9181 gctatccatt ttagaatata taatcttaga tatgatgaat ttattatata caaagactaa
     9241 ctataagaaa attcaatagt ttaatctgaa atacttcttg tttcaaagtg gatgatttta
     9301 gagcacggca aaatgtcctt gaaaaagttt attttttcaa aggttatctt gtggcaaatt
     9361 caggagttag aacacttttt ttcgtcaaat gctagcttgt tttttaggag ataaaacaga
     9421 tttctaataa gttttttggc aaggtgaatg atggctacat tgtaatgctt tctttgttac
     9481 aacttagtcc taagataggc tttaaaaaca ggcgaaaagc gagcatatgc tttggtagct
     9541 tgtatgagtg cccaacgtag atgaggggaa cccagtttga ccattttccc tgctaaatcg
     9601 atttgacctg actggtaaat agaaggattc ggtccagcaa aagcttgtaa ttgatgaggc
     9661 ttatcgaaga tatgaatact tcgaatctca actaagataa cgtcacctaa acgattccca
     9721 agctcacttg gttatccacg aactttgtgc cttgttacct tacacaatat aaaacgttta
     9781 tgcgctatca aactcattac caattgaaac aaaaagctgt ggttagagcc tttcagaaat
     9841 cgtcaagcga ttggaggaaa tgaactaatc cacagtggct tattccaagt gtaccacttg
     9901 gactttagca gtagcgaact acactaaata taatataagg agaaataggt gagtaaatta
     9961 atattgaact tgaaattaaa ttctttttta tttgttataa ttttactttt agttgttgtt
    10021 actccgactc ataccttaat ttttgatgca ctaattccaa cgaaaattga taatttatgg
    10081 agagagtttc ttctagtaat ttcttttcta tgtattctaa agataaatgc aggaaaaatt
    10141 aaaattggaa agctaggggg cccaataatt gttatgggag gaattggttt agtttatact
    10201 atctgttcag ataggccatt tacagcttta aatcttttta gaatttatat gtttcctgct
    10261 gtaatatatt ttataataat aaattgtaat tttcgcaagg agagattact gatattgaag
    10321 caagcgcatg tatatactgc ttgcatatta gctttatggg gaatttttca ggcgtgggtg
    10381 ttaaaagatc agtttttgat taaaatagga tatccttccc aaggaaattt tctaaagagt
    10441 acagcttttt atattggtgg ttttttcggt caacaacgag ttactagcac tttttctgct
    10501 cctaatttag ctggagttta ttttggaata tctttgatca ttttactctc tatatttgat
    10561 actataaaga gtaatagatt ggtattgttt tcaattgtag cagcttttgt tcttacattt
    10621 agccgtagtg ctattataag tactcttgta ggaatcgtat tctttcaacg taagaaattg
    10681 ttttcaacga cgaagattaa tgttatgacc ttggtaatct tccccttaat ttttttgatt
    10741 gttttagtta tattttatct ttatcctgag aatgttatta taaatatgct ctatagcagt
    10801 tattcttcaa cacttaattt gacagattct tcagcggtta agcatttgga agacttatgg
    10861 cttcctcttc taaaagttat tgattatcct ttgggacttg gatttggtaa taatggccca
    10921 attgttctgt cactctatca ctcagcaaat ttagtagaat cttctattta tcttcttgca
    10981 tatgattttg gtattttagg aatgttcata tatttgttcc cttattttta tacgattttt
    11041 gtatataaaa aatatttgct tagcggtgct atatgctgct tagttcttat aacttatcta
    11101 tttcttccaa atgtagaaaa ttttgaaatc atatttttta tttacctttt cattgggatg
    11161 gatgaactag cactatatac aaaaggaatg aatgtacatg aaattgatta aattattgaa
    11221 aaaatatata aatttataca ttagtagttc ggtgcctaag acaaataaat tgttaatttt
    11281 tggatcatgg ttaggtgaaa aatatgcaga caatccaaga tatttgtttg agtatgtgat
    11341 taagaatcgt cccgatttaa aagctatatg gattacaagt aatcaagatg tttttaaaga
    11401 attacagaag aaacaatatc tcgtgatgat ggcagaggca cctgaaactc ggaaaattgt
    11461 taaaaaagca aagtatattt ttacagcaac tggtattttt gatattggag aacaaaatgc
    11521 taacttcgtt ggaggtgcct atctaattaa tctatggcat ggcattcctt tgaaaaaaat
    11581 catgtatgat gataaacatt cagcacttca caaacgtagt aaactagtga cttgggtaga
    11641 aaaaattcct cttcgaaact attttgttat ttctactagt acggcaataa ctcaaattta
    11701 tcagtctgct tttcgcgtaa agaaatctaa tatattagaa cttggtcaac ctaggaatga
    11761 ctatttttat gataagtcta atccagtgag ttcattaata caggaattaa aaagtaaaaa
    11821 tattatctta tatatgccga cacatcgcaa tgaaggaaag aaacaaatag atctagataa
    11881 gttaatggat ttagaacact taaataattg gtgtgaagaa acaaagtcaa tttttgtaat
    11941 taaaaagcat ttctatcatt caaaagaaaa aactatcgat aagaaatatt cttcgataat
    12001 tgacgtgaca aatgagaagg tggatgttca agaattactc aaatgttcaa atgttttaat
    12061 aactgactac tcaagctgct atattgacta cttattgttg aatcgtccaa ttatattttt
    12121 taattatgat tatgatgatt acttgcgggt ggatcgttcg ctatattttc catatgagaa
    12181 tgttactcca ggggagaaat gtcaaaactt tgatgaatta ttagtgactt tgcaaaatct
    12241 atatgtagga aaagatgatt atagagaaga acgtgaaaat atcaaaactt tcttttattc
    12301 tagtgaaact cagaagtcag tttctgaaaa aataattaat cacgtactaa atctataact
    12361 ttattggaat ctgtcatgaa aaaaatatta aataagtatt attctttatc taatcctgta
    12421 aaagcttcaa tttggtttac tatttgcaat gttcttcaaa aaggaatttc aatgattact
    12481 gttccagttt ttactagagt attgacaacg gaacaatatg gtgtatactc tgtatatcaa
    12541 tcatggtatt caataattgg agtttttgca acactaaacc tatattatgg agtctttaat
    12601 aatggaatga ttaaatacga gaaagataaa aatgtcttta cttcctctat gcagggacta
    12661 acaacaacag ttacagctat atttttactg atatatttaa tagggattga tttttggaac
    12721 tcgttgttag gcttacctac actactaatc ttagtgatgt tctttgattt gttttttacc
    12781 cctgcttatt ctttttgggt tgctcgtcag agatttgaat ataaatatag aaacttagta
    12841 tttatcacat ttattatagc gattggaagt cctattattg gtatttctgc agttgtttta
    12901 tcgacttata aagcggaggc tagagttatc tcatttgtgt tagttcaatc ttgtataggg
    12961 ttatatttct atattttgaa cctttaccga ggtaaacatt ttttttgtaa aaaatattgg
    13021 ctctatgctt tgaattttaa tttacctctt attcctcatt atttatcgca atcagtttta
    13081 aaccaatcgg atagaataat gattaattca atggtaggaa tgggagaagc agcaatatat
    13141 agtgttgctt acagcatatc aattttgatg cttttagtga caagtgctat aaacagctct
    13201 tttattcctt acacatataa gtgtattcga gataagaaat atactgaact agggaaaagt
    13261 gcaaatcttt taattactct ggtaggcatt ggttcgattt taactatttc tcttggacca
    13321 gaaatcattc aattatttgc accaaaacaa tattacgaag caatatggat tattcctcct
    13381 gttgctctgt cagtatattt catgttctta tatcccattt ttggtaacat tgagttttac
    13441 tttgaagcaa atcattttgt aatgtgggct tcaatcggtg gagcaattat gaatattttt
    13501 ttgaatttta tttttttaaa acactttgga tatattgcgg caggctatac aactttattc
    13561 tgttatattt tatttgcgtt gggacattac atttttatga ggagagtact gtatcagaat
    13621 ctttcgggta tccaaattta taattccaga tatcttttat ttttttcgat tcttcttatt
    13681 attctaatgc tactaatcgt gattatttat ccatttatac tgattcgtta tcttactatc
    13741 tcactcatcc taggaggatg ttttttaaag aggaaaaaga taatgagttc gatagctatc
    13801 attaaacaac agtgaggtac aagaatgaca gaaacaaata aacagttaca tgaaacatta
    13861 atcgaaattt tagactttgt aaaagaaatt tgtgaaaaac atgaattaac ttattttttg
    13921 gtctttggga cagctcttgg agcaaaacgc cattgtggat ttattccatg ggatgatgat
    13981 gttgatattg ctttgccacg agagcactac aatatattta tcgatgcatt atctgagacg
    14041 gatcaatcta tatttagtct tcaaaatgaa gataacgagc cgaattattt tttaccattt
    14101 gctaaattaa gaaaaaacaa tacgattttt attgagaaga ttcttgatgt tgaatatgag
    14161 aataacggca tttacattga tatttttcca ctagatttcg tagagaatcc ggactctttc
    14221 aattttaaga ttaggagaac tacatttaat tatataaagc atattttaaa attttcaagt
    14281 tgcagaagtt tttataaaaa taaatacagt aatgtgcgtt atttgattga aaatattatg
    14341 agtattccta ccctgttttt ttcaaatagg agattattat tcttagcgaa tagtttaatt
    14401 tcatcaacga ctaaagctga ttttattggt caatatgatc agaaaagtaa caaaagagct
    14461 attatgcctt caaactatta ttttccacct aggtccgctg tgtttgaagg aaagacctat
    14521 agtgttcctg cgaaattaga agattattta aaatgttttt atggctcgga ttatatggaa
    14581 ttaccaccaa tagaaaaaag agtcactcat caaccaataa cacttagatt cgaaaaataa
    14641 tttgctattc tgtagaagga gaatataatg aaaagagtaa ttacatatgg aacgtttgat
    14701 ttacttcatc atggacatat caatttattg cgacgtgcaa aagaattagg tgactatcta
    14761 gtggtagttg tttcaagtga tgaattcaac ctaattgaaa aaaataaagt ttgttatttc
    14821 aattatgagc atagaaaaag tctagttgaa gctattagat atgttgacct tgttattcct
    14881 gaaacgagtt gggaacaaaa acgcagtgat gtcaaagagt atcatattga tacttttgtg
    14941 atgggggatg attggattgg agaatttgat tatctaaaag aagaaggagt tgaagtcgtt
    15001 tacttacctc ggacgaaaga aatttcgaca actaaaataa aaaaagattt atcaatgtaa
    15061 tattcgtaaa taagcattgt tctgttattg ttctcgaata gaccactgta tttttaagta
    15121 gaaatgctaa aatcgataga aaagagaaaa atgataggac actaccaata taggtaaaaa
    15181 atatcgtaat tagataaata agaaaggtac cctactatga aaggtattat tctagcaggt
    15241 ggttcgggga cacgtttata tcctttgact cgcgctgcat caaaacaact tatgccggtt
    15301 tatgataaac cgatgattta ctacccactt tcaacattga tgttggctgg gattagggat
    15361 attttgatta tttccactcc acaggattta catcgattcc aagagcttct tcaagacgga
    15421 tctgagtttg ggctcaaact ttcttatgca gagcaaccaa gtccagatgg tttggcacaa
    15481 gcctttatca ttggggaaga gtttatttct gatgatagcg ttgcgctgat cttaggtgac
    15541 aatatctatc acggttctgg gctttccaag atgctacaaa aggcagcgag taaggagtcg
    15601 ggagcaactg tttttggcta ccatgtcaag gatccagagc gctttggtgt ggttgagttt
    15661 gatcaggata tgaaggctat ttctattgaa gaaaagccag agcaacctcg ttcaaactat
    15721 gcagttacag gtctctattt ctatgataat gatgtagtag agattgccaa gagtattaaa
    15781 ccaagtcctc gtggtgaact ggaaattaca gatgtaaaca aggcttacct agatcgtggt
    15841 gatttgtctg ttgagcttat gggacgtggc tttgcttggc tggatactgg aactcatgaa
    15901 agtttactag aggcttcaca gtacatcgaa acagtgcaac ggatgcaaaa tgttcaggta
    15961 gcaaacttag aagaaattgc ttaccgtatg ggctatatca gtcgagaaga tgtattggcc
    16021 ttagcccaac cacttaagaa aaatgaatac ggacagtatc tgctccgttt gattggagaa
    16081 gcatagatga cagataattt tttcggtaag acgcttgcgg cacgcaaggt tgaagctatt
    16141 ccaggcatgt tggagtttga tatccccgtt catggagata atcgtggctg gtttaaagaa
    16201 aatttccaaa aggaaaaaat gcttccactt ggatttccag agtctttctt tgcagaagga
    16261 aaattgcaaa acaatgtatc cttctcacgt aaaaatgtcc ttcgaggtct ccacgcagag
    16321 ccttgggata agtacatctc tgtagcagat ggagggaaag ttctgggttc ttgggttgat
    16381 ctacgcgagg gtgaaacctt tgggaatacc tatcagacag tgattgatgc gagtaaggga
    16441 atctttgttc ctcgaggcgt agctaatggc ttccaagttt tatcagatac agtgtcatat
    16501 agctatctgg tcaatgatta ctgggctctt gaactcaaac ccaagtatgc ctttgtgaac
    16561 tacgctgatc caagccttgg tattgaatgg gaaaatattg cagaagcaga ggtttcagaa
    16621 gcagacaaac atcatccact acttaaggat gtaaaacctt tgaaaaaaga agatttggaa
    16681 taaggaaaga atatgactga atacaaaaat attatcgtga caggtggagc tggctttatc
    16741 ggttctaact ttgtccatta tgtttacgag aactttccag atgttcatgt gacagtccta
    16801 gataagttga cttatgctgg aaaccgcgcg aatattgagg aaattttagg taatcgtgtt
    16861 gagttagttg ttggtgacat tgctgatgcg gagttggtag acaagttggc tgctcaagca
    16921 gatgctatcg ttcattatgc agcggaaagc cacaatgata attcgctcaa tgatccatcg
    16981 ccatttattc atactaactt catcggaacc tatactcttt tagaagctgc tcgtaagtat
    17041 gatattcgct tccaccatgt atcgacagat gaagtttatg gggatctccc tttacgcgaa
    17101 gatttgccag gtcatggtga aggaccaggt gagaaattta ctgctgaaac aaaatacaac
    17161 ccaagctctc cgtactcatc aaccaaggca gcctcagatt tgattgtcaa agcctgggtg
    17221 cgttcttttg gagtcaaggc aacgatttcc aactgttcaa ataactacgg tccttatcaa
    17281 catatcgaaa aattcatccc acgtcagatt actaacatcc taagtggaat taagccaaaa
    17341 ctttacggtg aaggtaagaa tgttcgtgac tggattcata ccaatgacca ttcttcagga
    17401 gtttggacaa tcttgacaaa agggcaaatc ggtgaaacct acttgattgg ggctgatggt
    17461 gagaagaaca ataaggaagt tttggaactt atccttaagg aaatgggaca agctacggat
    17521 gcctatgatc atgtgactga ccgtgcagga catgaccttc gctatgcgat tgatgccagc
    17581 aagctccgtg atgagttggg gtggaaacct gaatttacca actttgaagc tgggctcaag
    17641 gcaacaatca agtggtatac agataaccaa gaatggtgga aagcagaaaa agaagctgtt
    17701 gaagccaatt atgctaagac tcaggagatt attacagtat aaaaagcagg aaatagctgc
    17761 tttttattgc tatattggga agagttacat attagaaagg tctagagatg attttaatta
    17821 caggggcaaa tggccaatta ggaacggaac ttcgctattt attggatgaa cgtaatgaag
    17881 aatacgtggc agtagatgtg gctgagatgg acattaccaa tgaagaaatg gttgagaaag
    17941 tttttgaaga ggtgaaaccg actttagtct accattgtgc agcctacacc gctgttgatg
    18001 cagcagagga tgaaggaaaa gagttggact tcgccatcaa tgtgacgggg acaaaaaatg
    18061 tcgcaaaagc atctgaaaag catggtgcaa ctctagttta tatttctacg gactatgtct
    18121 ttgacggtaa gaaaccagtt ggacaagagt gggaagttga tgaccgacca gatccacaga
    18181 cagaatatgg acgcactaag cgtatggggg aagagttagt tgagaagcat gtgtctaatt
    18241 tctatattat ccgtactgcc tgggtatttg gaaattatgg caaaaacttc gtttttacca
    18301 tgcaaaatct tgcgaaaact cataagactt taacagttgt aaatgaccag tacggtcgtc
    18361 cgacttggac tcgtaccttg gctgagttca tgacctacct agctgaaaat cgtaaggaat
    18421 ttggttatta tcatttgtca aatgatgcga cagaagacac aacatggtat gattttgcag
    18481 ttgaaatttt gaaagataca gatgtcgaag tcaagccagt agattccagt caatttccag
    18541 ccaaagctaa acgtccgcta aactcaacga tgagcctggc caaagccaaa gctactggat
    18601 ttgttattcc aacttggcaa gatgcattgc aagaatttta caaacaagaa gtgagataag
    18661 tagtagaatg attttctagt ctaataaaag aggcagataa tgaactccaa aggagcttaa
    18721 gatgtacgct tatcttgttg ttggtgctgg tctctttggc gcatagcttt ggctcagttt
    18781 ctattatcgc tcacaccatc catcagaagt ttaatctgaa ggtacccaat tatcgccaag
    18841 aagaagattg ggctaggatg ggtttaccaa tcacacgtaa ggaaatctct aattggcata
    18901 tcaaggcaag tcaatactat ttagagtccc tttataagct tttacgagaa aagttgttag
    18961 aacaacctct tcttcctgcg gatgaaacct cttatcgggt tctagagagt gatagccatc
    19021 tgacctacta ttggaccttt ttgtctggga aagctgagaa tcaagcaatc acgctgtacc
    19081 atcatggtca gtgtcgaagt ggtttagtag tacaagaatt cctaggagat tattctggct
    19141 atgtgcattg tgatatgttg cggcagtaac ttaggacttt agtcctctag ttctgcctat
    19201 gcgatagcag tccaaggttt aggagcaagg cgacgctaag cttggtaaac tgcgaaccgc
    19261 tagaagctta tcgtcaactg gaagaagctg cacttgttgg atgttgggca catgtgagaa
    19321 ggaagttttt tgaagcgacc cccaagcaag cggataaatc atccttagga gctaaaggtt
    19381 tagcttattg taatcagtta ttttccttgg aaagagactg ggaggctttg ccagctgatg
    19441 aacgactaca gaaacgtcaa gaagagctcc aacccttaaa ggaagacttc tttgcttggt
    19501 gccgccgtca gtcagtttta gcaggttcaa aactaggaag ggcaattgaa tacagcctca
    19561 agtatgaaga aacctttaag actattttga aagacggaca tctggtcctt tccaataatc
    19621 tagctgaatg ctccattaaa tcattggtta tgggacggag taaaagagtc cagtggactc
    19681 ttttagccta agctcagttt aaaaaagcga gggtggttat tttctcaaag ttttgaagga
    19741 gctaaagcaa gagctattat tatgagtttg ttggaaacag ctaaacgtca tcaattaaat
    19801 agagagaaat atctattcta tcttctagaa tgtcttccaa acgaggaaac tctcgtaaac
    19861 aaagaggttt tagaggctta tttaccatgg actaaagttg tacaagaaaa gtgcaaataa
    19921 gaaatct
//
LOCUS       DBERXF010000041        19853 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.41, whole genome shotgun sequence.
ACCESSION   DBERXF010000041 DBERXF010000000
VERSION     DBERXF010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.41"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(739..1417)
                     /locus_tag="ACL8JK_001682"
                     /pseudo
     CDS             complement(739..1417)
                     /locus_tag="ACL8JK_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(1485..3307)
                     /locus_tag="ACL8JK_001683"
                     /pseudo
     CDS             complement(1485..3307)
                     /locus_tag="ACL8JK_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1250 family conjugative relaxase"
     gene            complement(3294..3659)
                     /locus_tag="ACL8JK_001684"
     CDS             complement(3294..3659)
                     /locus_tag="ACL8JK_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HGS1786532.1"
                     /translation="MENRYRTNLKKVFLSDSELGQLKHCIDQSGCQSFSEYARRTLLD
                     PGMNFITIDTTGYQDLVFELKRIGNNINQIARSVNQSQLISSEELQDLKKGIADLIRE
                     VEKEFSIQAKKLREFHGHH"
     gene            complement(3664..4020)
                     /locus_tag="ACL8JK_001685"
     CDS             complement(3664..4020)
                     /locus_tag="ACL8JK_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1252 family conjugative relaxosome accessory
                     protein"
                     /protein_id="HGS1786533.1"
                     /translation="MPEQYRDIRKEVNLTANELEMIGVMMKNKGFEHFSSFARNKLLE
                     NELEMTAEKWFTFWRAQKLEQISRDVYEILILSRAEHQVTQEHVSILLTCVQELIQEI
                     GNSIPLSQDFRKKYMR"
     gene            complement(4914..6452)
                     /locus_tag="ACL8JK_001686"
     CDS             complement(4914..6452)
                     /locus_tag="ACL8JK_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HGS1786534.1"
                     /translation="MSDIATQDKNVKKELLEYQGNILILANAGSGKTTFLTKKLKSDS
                     KRLNNYQKLAAITFTRNATEEIKQKLVDIPDNVVVSTIDSFLDKEIILPFLNQKYEIQ
                     TSVQFSFRIDHNFSDYSTGIKQILQDGIFGTYDFPTSKHGKNFKCEVALDILKTIDSA
                     SEYIKYKFNTLYIDEFQDCDQSMNDLFLYLKNELGIPLFIVGDDKQSIYQWRGASPKY
                     INNLWKNKNDFRKKRFIGNFRSLPRIVDFSLALTPEVTVDNIREEGSILYLEPNQDYP
                     KEDIIKYLIDNGDINLQEKNYFLIGINKDIEETATHLNDILSNKVDYVRKNPFIDCTN
                     SNFLQSMAQYYFLEDFSEYDVLNNLFPEYNDEFRKELLKKLKRLRQRPTQSLIEEIAS
                     YLDVSITNYEDKLESQILLEILSNLDNKKMFDTNLMSNNLLMTTHASKGLAADTVVIF
                     VEYLIDWRTGLKFEDHYVAITRAKSKVIIIDNRTIYTSEINRLLSNNNGNFSFEDFIE
                     RRYI"
     gene            complement(6445..8202)
                     /locus_tag="ACL8JK_001687"
     CDS             complement(6445..8202)
                     /locus_tag="ACL8JK_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS1786535.1"
                     /translation="MEFKKLVIENFRNFSSIEVALSNKNVIFGMNDSGKTNLLFAIRY
                     LLDRTIRNKGFIKSDYYRHDTSRPIKIQLELDLSDRKMEGDEESLKSSHSRLLISTVA
                     GARNNSSLDTFFISLEAVYNEKELFGNPVLSWGSTLDNLVEVPQYGTRSDIDKIFQIV
                     YVNPAIELDSFFKRNRRILFSDDSKTDEDVKLEEEIENNIEKLNENISNLHLITSVQS
                     QLTEAYKSYRKENLEIKIQSEISISGYLDNLTPYINWNDDTHNYPTSGDGRKKLLSYA
                     INHLISEKQYNKKVIIYLIEEPENSLHRSVQISLSKQLFVQNIYEYFFLTTHSAEVLY
                     EMDNTQLIKITNQQDATGQSVYYTVPNEFSNLKKKLNKSLAQSIFYDRILLVEGPSEY
                     YLFSAIFEYVSPNFEADGKYLLQVDGINFKPYSELYKALGIDFWIKTDNDLKASRGDK
                     HVFSPIGLNRCIDLLDHSATPILDNYRIDFSSKDERKQNIKSKKEELYLTNHNLVLQL
                     NADGIFISEIDLENDLAQVLSDSERNEMSKLDFVNWLQSSKQYNMLEYISNHLTKEIA
                     LKIVESGYFKVLAEFLDYE"
     gene            complement(8192..8968)
                     /gene="pezT"
                     /locus_tag="ACL8JK_001688"
     CDS             complement(8192..8968)
                     /gene="pezT"
                     /locus_tag="ACL8JK_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin PezT"
                     /protein_id="HGS1786536.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKFSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSSVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLRVVEERHKELEGKNSYGI"
     gene            complement(8968..9444)
                     /gene="pezA"
                     /locus_tag="ACL8JK_001689"
     CDS             complement(8968..9444)
                     /gene="pezA"
                     /locus_tag="ACL8JK_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PezA"
                     /protein_id="HGS1786537.1"
                     /translation="MIGKNIKSLRKTHDLTQDEFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(9889..10314)
                     /locus_tag="ACL8JK_001690"
                     /pseudo
     CDS             complement(9889..10314)
                     /locus_tag="ACL8JK_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10291..11024)
                     /locus_tag="ACL8JK_001691"
                     /pseudo
     CDS             complement(10291..11024)
                     /locus_tag="ACL8JK_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
     gene            complement(11186..12070)
                     /locus_tag="ACL8JK_001692"
     CDS             complement(11186..12070)
                     /locus_tag="ACL8JK_001692"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGS1786538.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKTFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(12182..13036)
                     /locus_tag="ACL8JK_001693"
     CDS             complement(12182..13036)
                     /locus_tag="ACL8JK_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HGS1786539.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(13094..13852)
                     /locus_tag="ACL8JK_001694"
     CDS             complement(13094..13852)
                     /locus_tag="ACL8JK_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGS1786540.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFYEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYVGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(13914..14102)
                     /locus_tag="ACL8JK_001695"
     CDS             complement(13914..14102)
                     /locus_tag="ACL8JK_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HGS1786541.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(14425..14991)
                     /locus_tag="ACL8JK_001696"
     CDS             complement(14425..14991)
                     /locus_tag="ACL8JK_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786542.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPGENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(15259..16937)
                     /locus_tag="ACL8JK_001697"
                     /pseudo
     CDS             complement(15259..16937)
                     /locus_tag="ACL8JK_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(17029..17190)
                     /locus_tag="ACL8JK_001698"
     CDS             complement(17029..17190)
                     /locus_tag="ACL8JK_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786543.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(17874..18578)
                     /locus_tag="ACL8JK_001699"
     CDS             complement(17874..18578)
                     /locus_tag="ACL8JK_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HGS1786544.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINKGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIDKEREGEIDKKSTPIFYGEF
                     KNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLR
                     QKGLNKKMNYDVGESL"
     gene            complement(18705..19232)
                     /locus_tag="ACL8JK_001700"
     CDS             complement(18705..19232)
                     /locus_tag="ACL8JK_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HGS1786545.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            complement(19418..19591)
                     /locus_tag="ACL8JK_001701"
     CDS             complement(19418..19591)
                     /locus_tag="ACL8JK_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786546.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            complement(19665..>19853)
                     /locus_tag="ACL8JK_001702"
     CDS             complement(19665..>19853)
                     /locus_tag="ACL8JK_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786547.1"
                     /translation="IKYSVDFVNKELGIDLSIEIDKLIKQGEKPSVIAQIKKFQDQVN
                     KDNEYREMMKNKKMDQER"
BASE COUNT         5830 a         3893 c         2697 g         7433 t
ORIGIN      
        1 ttgttttggt gcctgaggga catcttatat tggtgaacct tcatctagtc attacgtgtc
       61 aaagtccagt tctatcagac cactcatttt acagacacaa gtgaagtagg attacttcga
      121 ttagttgttc accccttcgc tccacttcca ctacagaagt ttcctcacta ctatgggctc
      181 ggctgacttc tcatgattcg ttgttactac gctttcggcg ctcatgagac ctcacgggat
      241 aagccgtaca tctttcctcg tttatacaag atatgaggac gttaaaaggt tacaatgaaa
      301 ataggaaatc tgacgcagag tctttagact ctaggaagat ttatcttttt cacatagacc
      361 ttagtccgaa ttcaattact ctcgtgattt acgcatatag gttacgacta cctttttgga
      421 ctttagagtt ttaagccccc ttatccgctg tatacgcctt actatcacgt tcctgttcgt
      481 agagcctcga tttcgctatc ccttcctctg acgattctta tttcctgcgt cagacttaaa
      541 acggtctatc cccagaccgt tttaatccgc tacctcacga tagtcaggct tgggaatcgc
      601 tattgggttc accggtagcg ggtgcccacg gaggacttac acctcagatg cacgacatgc
      661 ccgtcgtacc ttaaaaagcc ttggaaaaaa ctgtttccaa ggctttctct atatttgtcc
      721 ttattgacca aaccagttac attgctttat cgtatctgtg attttagtaa tagcctcttc
      781 agtattattc tgcaaccata gatagcgaca aacattataa ttaaatttaa tagaaaggtt
      841 taattcttcg attgtgttta acttgagttg atttacttga tactctaact tttctctaat
      901 ttcattaaaa ctctctaaat cttcaatatc ataataaaaa ttgaatagag tatttgcaac
      961 ttgagggtag gtcaagtcag ttacacttaa ctgagatagt accttctcca atattgccac
     1021 agcctcctct ttttgcccat agaaataaaa atctataaga gattttatcc actccatata
     1081 aaatttattt accagagaca agcgatgtac ctttacactc tctaattcat atatatttca
     1141 aagattcata atttcgattt gtgataaatg tctgggctaa ctttttaaac tctgataact
     1201 catcaatctc ttctacaatc tgctcattaa aaaaataatc tacactaact tttaacttct
     1261 tagacagagc atataaaaag tctgctcctg gagtaaattc tccattctct aatcgactaa
     1321 tctgtccctg tttacatatc ccctcagtca attctcgctg agacattttt aattcttttc
     1381 gtctattttt taatctggtt gctaatagtg tgcccaagtt tgcattttcc ttttctattc
     1441 gatttcaaaa gatacaaatt atatataagc aatgactaga taggttattt ttgaaaacct
     1501 atcccttctt cttttgaaat tttcttactc aaacgattga taaacttatt caatttaaat
     1561 acgatgttct catatctatc gctctctaat tctatttgga tacctaactc attcaactcc
     1621 ttctcaacaa catcaatgcc aattttatca gttatattca actttgaaag attcattttc
     1681 atttcttgct tattttcaac tgaagccagt aaatattctg ctacttgatt taaggttgtc
     1741 actcgttctt gaaaagcatt gattctcaat tcagaagctg ctaattcatg aactagttca
     1801 tctttaattg taatataaga gtgcttatcc gtatccagct caagtaaagt atacacttcc
     1861 tcaatcttct cctttatcat ctccacagtt gttttcctgc ggaacggaat tgtttgattt
     1921 tcagagctga attggcgaat taatgttcta cctttcatat agcaattttt ctcggcatca
     1981 tctttgtaat agacatagta ggagctcgtt tctctgataa aaaccttcac cttatcctcc
     2041 tccatatcga gctccatgtt aggcaaaaag ataagccctt cctgacgaat accaaacttg
     2101 accttgatgt aaataccatc atccactact ttttcaattt gattgagtga caactctacc
     2161 tcaaattcat gaatagcatc tctatttctc ctgaactctt gataggactc ccaaaacttc
     2221 tcctcgcttg ggagtctttt tcttttgaga atctttcttc ttgataaact tgaactaaat
     2281 cctgaacttc tggagctttc aaatcttttc tcttctcaaa ataatctttg aaaaactcta
     2341 catcatataa gtttttcttg tctagttctg tttctttcac ttctactcct gcaaattgaa
     2401 aagaaacatg cttttgctta ggattgatat ttaatccaaa tagttttgct tttttaatca
     2461 gatcttctaa gttatcaacc ttgggtaaaa taaattccat aagctcttcc attttccttt
     2521 ttgcgaagta attcttgaaa aattcttctg tgtaagcttg cttgtgattg agtttattac
     2581 cacgcaccac ttgtctcata gttgagtccg tcataaaaaa ggtagcatgc ttgtgactga
     2641 aatccatctt cacatgtagt aatggagcgt tctttttgaa atcctcaaaa tcggtagaat
     2701 tttccatcaa aaaatagagt cgttgcttaa gttcatactt gtgattggtc ttacgataaa
     2761 ctttatactg atggtaagaa tagcgattct caataatttt tgcacctgca attttagaaa
     2821 atctatctga aatcatgcga agatttcgtt cgactttata attccacttt agttttttgt
     2881 ccgaattgtt atcaaccgaa ttaacaatga tatgattatg gaaatgattt ttatcaacgt
     2941 gagtcgcaac gataaaacga aatttaccac cagttaactc cttcattgtc tcatagccaa
     3001 tctgattgat ttgtttagga gtgagatgat cttcgggtga aaaggactga atgatatgat
     3061 gagcatgaat tagtcgttga ttttcctcat gcctgtcgtg gcgaaaatcg taaagcgtat
     3121 cattactgat aaaattttca tgatacatct gcaccatctc ctcataacta ggaaaatcca
     3181 gaaaattcct catgccatag tgcgatacca atgcaagatt ttcggtcttc tcaggattga
     3241 gaatatactt gataattttt ttgcgataac actttccgtg aacggcaaaa tgcttagtga
     3301 tgaccatgaa actccctcaa ctttttagct tgaatactaa actctttctc tacctctctt
     3361 atcaagtcag cgattccctt tttcaagtct tgcaattctt cacttgaaat caactgagat
     3421 tgattgacac ttcgggcaat ctggttgatg ttattaccaa tcctcttcaa ctcaaatact
     3481 aaatcttgat aaccagttgt atcaatggtg atgaaattca taccagggtc aagtagagtt
     3541 cgtcgagcat attctgaaaa agattgacaa ccgctttggt cgatacaatg tttcaactga
     3601 cccaattcgc tatcagacag gaaaactttc tttagattgg ttcggtaacg attttccatg
     3661 tgcctacctc atgtattttt tacggaagtc ttgactaaga ggaatggaat tccctatttc
     3721 ttgaatcaat tcctgaacgc aggttaagag aatggatacg tgttcttggg tgacttgatg
     3781 ttctgccctt gataagatta aaatctcata aacatcacga ctgatttgtt ccaacttttg
     3841 agctcgccag aaggtgaacc acttttcagc agtcatttct aactcgttct ccagtaactt
     3901 gtttctggca aatgaagaaa agtgttcaaa tcctttattt ttcatcatta cgccaatcat
     3961 ttctaattca tttgcggtca aattaacctc tttgcgaatg tctctgtatt gttctggcat
     4021 actacttcct cacttttatc tattgtcgga taattcccga ccccgtgtca accacgggaa
     4081 acttataaaa acaaaatcta tcatcttgta aggctttgcg agctcagata ttgtgtccac
     4141 aatatcccaa aaatcatatc gccagctaat caaaacctac cagttttgac agctaacgat
     4201 aagataactt ggtggctccg cccccaaacc cccagtgaag atttgaggtt ttattttctt
     4261 aagaatgata taagaatagc agagaaaatt tggaaaagat atcacaggag aatgagagga
     4321 tgaaaaaaag agagcaaatg ctctcaatga actcatataa atatatatca aaatactctt
     4381 caaaaacata aggttctaaa gattatgtag aaaaagcttt agcaagtctt aaacactctg
     4441 ttgctctaac ttatactggt cgatgctaaa ataatttaat tccttgaagt aattttccag
     4501 cttttaaatg atactcttga tttttcatct cctctaaacg actatctaca gctaaggcaa
     4561 atatattcca tattacattc catcttcgta tcttgttctt gtcatataat cttaaatgtc
     4621 atagagcatg gatttcatat tttgataatt aggtattcct accaatgctc gactagctct
     4681 atttatccct tcaacataac cctttgagtc attcaatata ccaaaattcc agaacctttt
     4741 agaattattc ggtgtctagt tgtaaccgta atactcgtaa aatggctaat gtagtacaat
     4801 catcttcatt ttttattttt caactcctgc actattaaaa tcaatgtgcc aattaattgc
     4861 agaacctaaa acacctgtaa tatcaaattg caatctatct tgatttagac tagtcaaata
     4921 tatcttcttt ctataaaatc ttcaaaagaa aaattcccat tgttgttact taataatcta
     4981 ttgatttcac tagtataaat tgttcgatta tcaataatta tgacttttga ttttgctcta
     5041 gtaattgcaa cataatgatc ttcaaatttc aatcctgtgc gccaatcaat tagatattct
     5101 acaaaaatta ctacagtgtc tgcagccaaa ccttttgatg catgagtagt cattaataaa
     5161 ttattactca ttaaatttgt atcaaacatt tttttattat ccaaattact caaaatttcc
     5221 aacagtattt gactttctaa cttatcttca taatttgtaa ttgaaacatc taaatacgaa
     5281 gctatttcct caataagtga ctgtgtaggt cgttgacgaa gcctctttaa tttttttaaa
     5341 agttctttcc taaattcatc gttatattca ggaaaaagat tattcaatac atcatactca
     5401 gaaaagtctt caagaaaata atattgagcc atagattgca aaaaattact gttagtacaa
     5461 tctataaatg gattttttct aacgtaatca actttatttg aaagaatatc attcaaatgt
     5521 gtcgcagttt cttcaatatc tttattaatt ccaattaaaa aataattctt ttcttgtaaa
     5581 tttatatcac cattatcaat aaggtactta ataatatctt cttttggata atcctgatta
     5641 ggttctaaat atagaattga accctcttct ctaatattat cgacagtcac ttcaggagtc
     5701 agagctaaag agaaatccac tattctaggc aaacttctaa aattcccaat aaatctcttt
     5761 tttctaaaat catttttgtt tttccataaa ttatttatat atttgggtga tgctcctctc
     5821 cactgataaa tagattgctt atcatctcct acaataaata aaggaatccc taactcattt
     5881 tttagataca gaaataaatc attcatagac tggtcacaat cttgaaattc atcaatatac
     5941 aaagtattaa atttatattt tatatattct gacgcagaat ctattgtctt caaaatatct
     6001 aaagcaactt cacatttgaa attcttgccg tgtttagaag taggaaagtc gtaagtcccg
     6061 aaaataccat cctgcaatat ttgttttatt ccagtgctat agtcgctaaa attatggtct
     6121 atccgaaagc taaactgtac agatgtttga atttcgtatt tctgattaag aaaaggaagg
     6181 attatttctt tatctaaaaa cgaatctatg gtcgatacaa caacgttgtc cggaatatca
     6241 actaattttt gctttatttc ctccgttgca tttcgagtaa aagttattgc tgctaatttt
     6301 tgataattat ttaatcgttt agaatcactt tttagctttt tagttaaaaa agttgttttt
     6361 cccgaacctg cgttcgctaa aattaaaata tttccttggt attctaacaa ttcttttttg
     6421 acattcttgt cctgtgtagc aatatcactc atagtctaaa aactccgcca aaactttaaa
     6481 atatcctgat tccacaatct taagcgcaat ctctttagta agatgattac ttatatattc
     6541 tagcatattg tattgtttac tgctttgtaa ccaattcaca aaatctaatt tactcatttc
     6601 atttctctcg ctatcggata aaacctgagc taaatcattt tctaaatcaa tttccgatat
     6661 aaagattcca tctgcattta attgtaatac tagattatga ttagtcaaat ataattcttc
     6721 ttttttagac tttatattct gttttctctc atcttttgaa gagaaatcta tacgataatt
     6781 atctaatata ggagtcgcac tatgatcaag caagtcaata cacctattta agccaatagg
     6841 agaaaataca tgtttatctc cacgactagc ttttaaatca ttatcagttt taatccaaaa
     6901 atcaatccct aatgccttat atagctctga ataaggttta aaatttattc catcaacttg
     6961 taataagtat tttccatcag cctcgaaatt gggacttaca tattcaaaaa tagcagaaaa
     7021 tagataatat tctgatggac cttcgaccaa aagaatccta tcataaaaga ttgactgagc
     7081 caacgattta tttaattttt tctttaagtt tgaaaattca ttaggaactg tgtaatagac
     7141 tgattgccct gttgcatctt gttgattggt tatcttaatg agctgagtat tatccatttc
     7201 ataaagaact tctgctgaat gagtcgttag aaaaaagtat tcataaatat tctgaacaaa
     7261 aagttgcttt gaaagagaga tttgaacgga acgatgtaag ctattctctg gctcctcaat
     7321 taaataaata attaccttct tgttgtattg tttctctgaa attaaatggt taatagcata
     7381 tgataaaagc tttttacgac cgtctcctga cgtcggataa ttgtgagtat catcattcca
     7441 gttaatgtat ggtgtgagat tgtctaaata tcctgaaata gatatctctg attgaatttt
     7501 aatttctaaa ttttctttac gataactttt ataggcttca gtcaactgtg attgaacact
     7561 agtaatcaaa tgtaagttag aaatattttc atttaatttt tcaatgttat tctcaatctc
     7621 ttcctcaagc tttacatcct catcagtttt agaatcatca gagaacaata tccttctatt
     7681 tcgcttaaaa aaggaatcta actctatagc gggatttaca taaactattt ggaatatttt
     7741 atcaatgtca cttcttgtac catattgagg aacttccact aaattatcta gtgttgagcc
     7801 ccagcttaat accggatttc caaataactc tttctcatta taaactgctt ctaatgagat
     7861 aaagaatgta tctaagctag agttatttct tgctccagct accgttgaaa ttagaagacg
     7921 agaatgtgaa gattttagtg attcttcatc cccctccatt tttctatcag acaaatcaag
     7981 ctcaagttgt atttttatag gtctactagt atcatgtcta taataatccg atttaataaa
     8041 acctttattt cgtatagttc tgtccaagag gtatcttatt gcaaatagaa ggtttgtttt
     8101 ccctgaatca ttcattccaa atataacatt tttatttgat aaagcaacct caatagaact
     8161 aaaattacga aaattttcaa ttactagttt tttaaattcc ataactattt tttccttcta
     8221 actctttatg tctttcttcc accaccctca acatctcttt ctctacctga ctccactccc
     8281 caaagagtaa ctcttgaaga acatctgctg ctgaagttgt attttctttt gaatcatata
     8341 cagaacttct atctcgttgg taaatttgaa ttctttcaaa gatagccagt tcttccaatt
     8401 gtcgtgtatt atcaactaga tgatttacaa tgaaatcatg atgttctttt ggagttgcgc
     8461 gtgcttgatt tggattgata atgtacagtt cttcataacg gataagagta cttagatacg
     8521 acaattcagg ctttgtcgca attaaggcca attgtacttc atatccctta tttttcaaga
     8581 gttgtgctgt tttctttgga acatcaactg ttcgtaaagt tccctctatc aaaagattgt
     8641 atctcaaact actaaatttt gttactaaag actctaccat ttttcctgca aaatctttgg
     8701 tatattctac actgtctttg ccatattctt gctgcagttc taaatagtgt ggatgctgag
     8761 aacgaaaact atcaccatct atgataacaa tatttccttg aaattctttc tgtttaatac
     8821 gatgaattgt agtcttaccg gcaccacttt gacctccaag caaaatcgct ataggttgct
     8881 tactggactt ttttcctctt gtcagtgaac gaagattcct tgctaaagca tgtttgaatt
     8941 cactatcagt ataatcttgg atttccatta agctaccatc cgcttttcag atatctctaa
     9001 catacgttca attccatcca aatagccact atatctctct atttcatcaa aagtttctac
     9061 taaatagata ttcgtatgaa tcaaatcaga aagatcatca ctcattaaaa tccaaggatt
     9121 agattcatca tcaatgctaa ttccctgact atcttgatag cgatagagtc gagataatag
     9181 attagcacct ctttctttca caatttcaat ttttaaagtc aattcataat cttcaacagg
     9241 attgagcatt ttatcttctc ctacgatatc gacataagat acattaaact tctgacaaat
     9301 gatgtctatt aattcggtag agactgaact cgttccattt tcataacgac tcagactatt
     9361 tcgtgaaata cctacaatcc gtgcaaattc gtcttgtgtt aagtcatgtg ttttacgtaa
     9421 ggattttatg ttctttccaa tcatggcaaa ctcctttatt tttataattc aattatagca
     9481 taaaaaagca taatgcacca aaaatggtgc attatttctt gtttttctat cctaaacttt
     9541 acttctataa aagtcaccta aagagccata aatatttatt cttgtattaa ttttttcgat
     9601 gcgcaaacga tatctacaaa tacatctata acgattcacc ttttaggatt tttattgtca
     9661 aaattgcctt tatctacaaa gacaaaatgc ttataaaata gcttgaaatc aaggattatc
     9721 acctttttcg ttgtagcaac actccacatg tgattattag gctattagca aagcgtatcc
     9781 aatacctcaa taaagtgttg tttttactga tattttaact atattgtata gtctactatt
     9841 taaatctcaa ttaggatatt ttatagaata cccaaaattc aacaataact aaaagtaaga
     9901 ttccattgta tttccttgtt ggtctttcat atcacgaatt ttatttttca gaatattaaa
     9961 gttacaaatt tcatctctaa tatcgttatc cgctctgtag ccattaatca tctcagtcag
    10021 agttttccct ttactaccat tctttatagt agtatttact ctttttatac tgctttcaaa
    10081 aggctcatat gttttatact taattacttc gtctttaaaa ttaaataaag gtgtatccgg
    10141 cttagcattc cataaaataa tcaaccacat tatagcatta taaagctact ttgcagtttc
    10201 attccacttt tcaggttgta aatttccact ccctgtattg tcatattctt gtctattatt
    10261 tacatgagaa tcacctacaa gcggattaaa aagaggtagc cctttgtgat taattagttc
    10321 taaaaaatcc cttgccgcac ccatgcaaca ctgtctccaa aatgacggtc aatttcaaag
    10381 taatctgtcg tattgtactt gtgattgctt gtagattcaa agatgggaca aagatatagt
    10441 ccagtaatac ccaagtcttg caagtaatcc atatgatcaa taatcccctg taaatcacca
    10501 ccaaagaaat catcgctctt aggtgtgaca gatgaatccc agtctaaagt cccttctggg
    10561 tttaatagag cattgccatt ggcaaatctt tcaggaaata tctgatacca taccgtatct
    10621 gaaacccagt caggaacctt gcaggcatca atctcatgaa gataaggcaa cttaaatcca
    10681 ttcccaattg catgaagatt ttctagagaa ttttccacac accctttatc gccatacaaa
    10741 atattttgac cttctgtatc tctgagctca aagagatact ggatacgtgc aaagtcaact
    10801 gacacttcaa cctgccaatg gtcaaataag gtaccagaag ttatcttgac catttctttt
    10861 gtatcctgat aaaactcctc cataaagata aaagggtccc catagtgcaa gttaatgctt
    10921 tcaatgtccc ctttcttagt tcgaattcga atatggagtt tcttatcctt ataaagatag
    10981 gcatactccg actcaggcct atggtaaata gcactcaatt ccatcaattt gtctcctaaa
    11041 gtattcattc aaattttacg caaacgtttt caaactcaat aaatccagta tactattttt
    11101 gtaaactatt tacaaggaat gtccgttgtt aaaggaacta tcttttaaag tatacaaaaa
    11161 gccttaaaaa ggctttctct atatactaat cctctttcgg ttttgaaaat acttctactc
    11221 gctgagctag gactttgatt tctacaggta ggttatctga tttatctccg tcaacatctg
    11281 actccaattc actatctgaa gagattttaa tattacgcgc tttgatatac tcgatattat
    11341 catttgcgac aacatcccct tttaataaat caggaatgac ggataatttg gagaatatag
    11401 aggcatcttt cagaatcaaa atgttggcat agccgtcctt gttttcttca aaggttttct
    11461 tatcagcgaa gtaatttgtc aaaaggacca aaacatggct agcttcacca acataatttc
    11521 cattttctgt ctcaacctta atattaaaga cctgatctgt catgacagac ttcatggtat
    11581 ttacagcata ggttaaaata ccgaattttg ttttgtcctc tatttcaaca ttgtgaatcg
    11641 cctcaggcag agaaccgata ctaaagatat aaccaaaata gttgtcattt gctttaccga
    11701 tatcaatctt attggttaaa tcaaaatcca gttcgtcaat tgcgccatcg atgtcttgat
    11761 tgatttccaa aagttttgta atgaggttac ccgtaccgcc tgggataatc cctaacttag
    11821 gaatgtagtc tctctcatca atacctgaaa tgacttcatt gacagttcca tctccaccaa
    11881 acacaaccac tgcatcatac tgctcacgag aagcttcttc agcaaaatgt gttgcatcca
    11941 gcgctttttc ggtaattttg gtttcaacat attcaaagta ttcttttgct ttattctcca
    12001 gcttttcttt gtaatccaaa gccttctcgc caccagaagt agggttgata attaccattg
    12061 cttttttcat tgattttatc cttaatttta aacagaaatg tttacatttc gtcgtatgca
    12121 agtaaatgta atcctattat acaatgaaaa tacagaaaag agaaatctga cgtactggag
    12181 attaatacgc ttttattcta ttttcccatc gcctaactac atcctttaag ggttcatcca
    12241 agtaagaata ggccttatcc ttgatccaat caggaatacc gtaagctgcc tctgctatgt
    12301 tacaagtgat tgctgcgaga gtatcactgt cgccaccaag tgagatggca tttcttatcg
    12361 catcttcgaa gtctctactt tcaagaaagg cgataatggc ttgagggaca gtttcctgac
    12421 atgtttcgtt aaaacgatag ttaggacgga tttcatctaa agtttgagat agattgtaat
    12481 cgtattcttt ttctatataa tccttaattc gtcttttaca ctctgtagga ttgtcgttaa
    12541 ttgattgctc gtactctcta caataaccac caaagtaaaa acgacataga aagatagcat
    12601 cagctgtagc catagcgcct ttgacacctt ctggatgatt atgagttacc tctgcagaaa
    12661 gactcgtaag tcctctagat gatggccata taccagtttt cgcataaaaa ccacagtcca
    12721 tgatccaagc acatggagaa atacgcatag ctgatccatt accaaagcta ttataaggct
    12781 cacggttatc gctgtttagc catgcattaa accgagcacc gtaatcagca ttcggataca
    12841 ttctgccata tttcttcatc gcgtcaatga agtcgtcttt ttgtccacca ttcataattg
    12901 cttctgcaac agcacaagtc ataaccgtgt catctgtaaa aaagcagtcc ttccgaaata
    12961 aaggaaagtc ctttgttttg atattgttcc attcgtaaac agaaccgaca atatctccaa
    13021 taattgctcc aagcatcaga ttcctccttg ttcattttga tgctttttat attggttatc
    13081 taccatattt attttagaaa ataacatcct gttggatttt aaaaatttca tttttttcaa
    13141 aatagggttt taccatttct ttccacctag ctctatgaaa attgattgat tttaaaggag
    13201 ataggccata atttcccaat gcataaccat catttacttc aacaacaagt gttctgccat
    13261 cgcgagtaac accgatatct agtccataag ctattggcgc atctttccaa catgatatcg
    13321 cttcatcaat tacacttgca tcaaattgtg catgataatc acctgtatag ggtcgaacat
    13381 ctaatacgcg accatctaac acaaaacaac gccattcagc tatgaattct acaacctcac
    13441 taatccatat aggatagtcg aaaggtagac caatacctat taaatcatgg gttccattaa
    13501 caactcttcc agtaaagact tttgaaccag ctttaggctt aataaatttt ccccaattat
    13561 caggtatatt cacaatctct cctaaaatac caacataaat ctttcgacca taaaactctt
    13621 taagctcaat aggatagtca taaaccggaa cgtttaagcc catcattttt agtaatgctc
    13681 tagtctccat tatataatct acaactatat cttcacttgt taactctttt atttcataaa
    13741 aagattgata taaaataact tcttctcctt gtaagtaggc acctacttga gcattgtatt
    13801 tattaattga aacctcactt ggtaatttac tttgtctaat ataaacaacc atttcatcac
    13861 tcctgtatca ctagtgttac accaatttgt aaaaaataat agcaattttg ctcttatttt
    13921 tttgagtaaa tagcccccat aatatcatcg aaataatcaa cggtatttag gagtaattca
    13981 ataacctggg actttgttag tcgcattccc cttctatctc tagcatcttc tactaaattt
    14041 tcaagtttct ctagattttt atcatccaag ctaatcatta ttctattttt atcggttgcc
    14101 attttcatca cctcaagtta attctatcac aggtgtaaca cttgtgttaa ctggctttta
    14161 taatacatta gtttaaaagt ggagaggatt ttttacacag taactttaaa tctttggtat
    14221 taaaaaattt tcacaatatt tatagaaata aaatctgtct caaatcagtt atcaaatcta
    14281 gtataaatta tgagcggcta ctctaatact ttccctctaa acaagaaaaa gacttacact
    14341 caaggatttt cttccccccc cttcgttata acgttttgac tcttttacta gcaaaggtat
    14401 atactcacaa ggaactttgg ttgactattg aatctctcca acttcttctt taacatatcc
    14461 ttctacatct tcaatctcta caaacattgg gtctaagtga cacaagaaat gccaaacttc
    14521 gatccctttt tttctgtaaa gaatcgcttc accgtcttca cttccgaaaa agcttctgtc
    14581 gatttcatat ccgcggcttt ctaagaagtc ttttgcttta cgatagttcg tttctcttgt
    14641 ttcgacatag gctttaactt catggttgtt aacgacatat gcatcaattt ttgaatatcc
    14701 ttcgatcact ctatcatttt tgagggataa atttgaaatc tctttccaaa taatgtttac
    14761 attttcccca ggatcgaaca taaatttaga taaaggaaca atatttccgt taaaaataat
    14821 ttccatataa tccggtatgt ttttaggatt aaaatactcc acttcaaaac catcttctgt
    14881 ttccagagtg tatcccggga tttgagctac aaaggctttc ccatcttcta tggaatcaaa
    14941 tgctactaaa tctttagaat aatcattttg gtacaattcc aatataacca tcgataatct
    15001 ctccattttc attatcaggc taatgtaaat aagcacgtca cctgaccaat tcaggctctc
    15061 tgtatcatct catcatattt cctacttact ttacgagtcc tatacccaga acacacctta
    15121 tcgaccttcg gtctcacctc gttgcattgg ctgaacatct acttttactt cgctgatgct
    15181 tcaactcgta caagcagtga taccgcctca gcgtgatgcg tcagtgggac tcaaaaggtt
    15241 cggggaacct tttgaggatt aactacgttt ctctaataaa cttacacatt caacttgttc
    15301 atcattgtcc aaacctatgt tgagattttc ttctataatt ggtagcttaa aagtaatgga
    15361 ttttagccat tgtccgttag attgtttttc ttcataaact tgaatttcag aaatcaaagc
    15421 tgaaattaac tgcctacgct ctacatcatt catgacttta tagagcttat caaaatagat
    15481 cagaacctta tatatgttat ctcctgtaag cttttcagct tcaatagtct gtttctttgc
    15541 tttcgcatca attagtgatg attctaattc atctattttg tcatacatac gatatagtct
    15601 atcatctaaa tcctgtttcc ttctcttata gtgcttatct tcaacatcta aattatctat
    15661 ttcctcaatt agcttaaact ttgtagaatg actctttctc aattcctttt ggtaattatc
    15721 tatttctttt tctatttcag aggtatccac cttcatgttg attttttctt gcatcataga
    15781 agcaaatttc ggattactta ctatcttgac aatcacctct gcaacagcat catctaacaa
    15841 ttcttctcta atttgcttac tgaatgtaca cttatgacct cttatcatct gcctatgttt
    15901 acaaccatag taataaaaat ctttatactt tgtgccatct ttctttttct tgatacactt
    15961 gttcccaaac attcccactc cacatatccg gcattttaca attccagaaa gcaagtgtgt
    16021 gcgtgtatct tttcctttat tcacatgctc atatttcttt gcttgagatt ttagcttaac
    16081 ctgagcagct tgccaaactt catcggaaac tatagcttca tgtatccctt cagatattag
    16141 atattcatct tgttcaacct gcttatattc atttcttgta ccatgaactt tttctaaagt
    16201 tcttcttcca aatactattt tcccattata tacaggattc tttaatatct ttcttataag
    16261 acctgcatca aacaaaggat tcttaccatt ctgtcttggg atttttctaa ttccatgatt
    16321 ctctaagtat ttagatatcc cattggctcc tatcgtagta tttacatact ggtcgaaaat
    16381 cgttcttatt gcaactgcct cttcctcatt tataaacagc ttgccgtctt caagtttata
    16441 tccatacgga gcaaagccac cattccattt tccttccctt gcttttgaat gcgaccttcc
    16501 attgtttgaa tacggatgtt ttctctttct atttcagcca cagctgataa aacagaaatc
    16561 attagtttcc cagcatcttt agatgaatca atgccatctt caacgcagat aagattaact
    16621 ccataatcct gcattatctg aagtgtagaa agaacatcag cggcatttct tgcaaatctt
    16681 gataacttaa acacaagaac aaaagatact ccatcttttc cagattttat atcttccatc
    16741 attcgattga actgtattct accttcaata gacttgccag acttcccggc atcttcatac
    16801 tctccaacaa tttcataatc attgtaaata gcaaaagctt tcattcgtga tttttgtgcc
    16861 tctaacgaat acccctctat ctgtattgac gtagatactc gtgtatagag gtatactttt
    16921 attttttctt ttgacatagt attaacctca atataatttt tctatatcat atataatttt
    16981 tttaatttaa gtttggacta tcatttcaag tatattataa cacttttatt agtccgtctc
    17041 aatttgtgtt tttgccatgt caaaactatt tttcatctct tgattttttg ctggcgttgg
    17101 atcgggtaga ttatctaaat ctaaagcacc agcatatttt gcaatcagat ttgctattaa
    17161 atcagccaat ccattccagt cattgtccaa tatatacctc ctctaaagtt ttatatctaa
    17221 taattatttg tttaattaag ttttttgaca ttgacaagtg ctttggatta gcaacatagg
    17281 aatctcacct ccgcctctat tccggatgag ccggcttcaa ccttagaagt atcattatcc
    17341 tcattttctt catagcggat agggtatccc tccctatatt caaactctta cttatcgctc
    17401 actttctttt tgctcagcag aacttttttt gccgaattat tcagccgaaa gatcttgacg
    17461 gataggttat tacgctccaa aaataattaa cgtcttgtct tggtctattc aattgttaag
    17521 gttcaaaatt tatcgagagt tattaatctt tttaaaattt gaccatcaga aaatatttat
    17581 cttgatgtaa taaaattcta taaattaccc tcttatactt aacagtgaaa agaagtcttt
    17641 cttggtaacc aattttgaaa tagaatttgc ttatataaaa aggtccaatt cctactgcat
    17701 aagtagcagt gaaaattaga ccctcttggt aactgtcatc taaaagtctt ctagcatttc
    17761 tttaattttc taatcgcctt taaagtgtca tatttatatt tttttatctc tggcatactt
    17821 tgataccttt ttagacttaa agtctttaat agtgcctttc cacctctttt tatctataaa
    17881 gattctccta catcataatt cattttttta tttaaacctt tctgtcttag tttgtcttta
    17941 tcttcttcat accattttaa gattgtcaca tagtggtttt gataggtctt accactgctt
    18001 tccatgtatc tggatagttt atttatcatt atatctgtgt gtgagtttaa tttttctttt
    18061 agatttttat attcttcttt gcttaacctt acatttttga attctccata aaaaatgggg
    18121 gtggactttt tatctatctc tccctctctc tctttatcta tctcttgtcg gacatgggtt
    18181 ggactcatta aggacaatgt tctctgttta ttttgtctgt atcttctttt tttctctgcc
    18241 caggctgttt ctgatccgat taagtttggt atttcagtta ggtagtattc atcattttct
    18301 gttacaactt ctaataagcc tttattgatt aaataattta ctgttaccat tacatcatcg
    18361 tctgtttcat ctatggttag tgctaactct tttataaaat cactttctac tccgtcataa
    18421 tagagtttgc cctcatcttt taggcttagt agtagaagtt ttaggtagat tatcgtatag
    18481 gtatctcctc cagatattct ccttaacctt tttatccttt tgtctgtgaa aaattcttct
    18541 tttaatttta tccaatagta tcttttgttt gttgccatat ctgctccttt cttgattttc
    18601 gataatcgaa attcttgatt tccgattttc ggaattctgg acttctgttt ttcggaagtc
    18661 ttgttattat ggttatttaa gggtgtaact tttcgttact ccctttagat ttctctggtc
    18721 atatcttttt tgtttggttt tactttttct tttactttcc tttttccttt ttcttttgtc
    18781 ttatctttgt ttttggatag gtctttgtat ttctttattt gttttaggat actttctttt
    18841 tcttttttat tttccttggc tatgacttgc ttaaaggcat attccattac ttttatgtct
    18901 ttggcttgga agaatatttc atagtttttg ctttctttgt ttttcattac tgagaaactt
    18961 actccaagtt tgtttagttc tttttttaag tctttgaggt cgatttgatc tatgcttata
    19021 ttttctagtt gtcctttctt gtagagatct tttattttca tttcatcgcc cataagactt
    19081 tttaagtttc catttgcttt ttctaaagtt tcattcatct tttttcttat ttctttttct
    19141 aaattgattg attcttttgt tgcctttatt gtgtatgata ttatggtttg tgctgcttga
    19201 cctgcttcct tgcttatttc ttcgtttatc atgcttttct ctcctttgtt tgaattaaaa
    19261 aagggaagta taggttttaa tttttctata cttccctttg cttgttttta ttttattgtt
    19321 cttggtggtg gaatacttta ttttgatgtt tttatatatt tcttaggtct ttgtaccttt
    19381 tatactttta aaaatagctt acactacctt tccaccttta atagtttatg tgtgttcttt
    19441 tgtctgatag atagtttttc atgttggaat atataatctg tatttcttca ttgttcattg
    19501 cttttatttc ttctgtgctt ttataggttt tgtatgttcc atcttcattt gcttttatga
    19561 gttcatctat tagctcttgc cttttattca tctctattac ctcctagatc tgactttagt
    19621 tgtttggtca tattatagct tggataagat atttttacca ggtcttatct ttcttgatcc
    19681 attttcttgt ttttcatcat ttctctgtat tcattatctt tattgacttg gtcttggaac
    19741 tttttaatct gtgctattac acttggtttt tctccctgtt ttattagctt atctatttct
    19801 atggataaat ctataccaag ttctttgttt acaaaatcta ctgaatattt tat
//
LOCUS       DBERXF010000042        19679 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.42, whole genome shotgun sequence.
ACCESSION   DBERXF010000042 DBERXF010000000
VERSION     DBERXF010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19679
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.42"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(109..918)
                     /locus_tag="ACL8JK_001703"
     CDS             complement(109..918)
                     /locus_tag="ACL8JK_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS1786548.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYITPPSKEMQEWYSHSIKAYRKN"
     gene            complement(920..1723)
                     /locus_tag="ACL8JK_001704"
     CDS             complement(920..1723)
                     /locus_tag="ACL8JK_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS1786549.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1733..3220)
                     /gene="tacF"
                     /locus_tag="ACL8JK_001705"
     CDS             complement(1733..3220)
                     /gene="tacF"
                     /locus_tag="ACL8JK_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HGS1786550.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYSYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNRIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIILLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3556..4263
                     /locus_tag="ACL8JK_001706"
     CDS             3556..4263
                     /locus_tag="ACL8JK_001706"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HGS1786551.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIENIIEAIDAYRPL
                     TSEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITGIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4268..5290
                     /locus_tag="ACL8JK_001707"
     CDS             4268..5290
                     /locus_tag="ACL8JK_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribitol-5-phosphate dehydrogenase"
                     /protein_id="HGS1786552.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5307..6176
                     /gene="licA"
                     /locus_tag="ACL8JK_001708"
     CDS             5307..6176
                     /gene="licA"
                     /locus_tag="ACL8JK_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HGS1786553.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDATSI
                     KTKFDKIVPILQTIHASGKELRGEFAPFEEIKKYESLIEEKIPYANYEAVREEVFSLE
                     KRLADLGVYRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGADFGYYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            6166..7044
                     /locus_tag="ACL8JK_001709"
     CDS             6166..7044
                     /locus_tag="ACL8JK_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS1786554.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            7056..7745
                     /locus_tag="ACL8JK_001710"
     CDS             7056..7745
                     /locus_tag="ACL8JK_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HGS1786555.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            7841..8689
                     /gene="dprA"
                     /locus_tag="ACL8JK_001711"
     CDS             7841..8689
                     /gene="dprA"
                     /locus_tag="ACL8JK_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGS1786556.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPASILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            9528..10571
                     /locus_tag="ACL8JK_001712"
     CDS             9528..10571
                     /locus_tag="ACL8JK_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HGS1786557.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            10738..12825
                     /gene="topA"
                     /locus_tag="ACL8JK_001713"
     CDS             10738..12825
                     /gene="topA"
                     /locus_tag="ACL8JK_001713"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGS1786558.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            13046..13405
                     /locus_tag="ACL8JK_001714"
     CDS             13046..13405
                     /locus_tag="ACL8JK_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HGS1786559.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13498..14130
                     /locus_tag="ACL8JK_001715"
     CDS             13498..14130
                     /locus_tag="ACL8JK_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGS1786560.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILKYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            14174..14830
                     /locus_tag="ACL8JK_001716"
     CDS             14174..14830
                     /locus_tag="ACL8JK_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGS1786561.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14900..15943
                     /locus_tag="ACL8JK_001717"
                     /pseudo
     CDS             14900..15943
                     /locus_tag="ACL8JK_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261078.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
     gene            15955..16992
                     /gene="leuB"
                     /locus_tag="ACL8JK_001718"
     CDS             15955..16992
                     /gene="leuB"
                     /locus_tag="ACL8JK_001718"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HGS1786562.1"
                     /translation="MAKKIVALAGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDYILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            16989..17258
                     /locus_tag="ACL8JK_001719"
     CDS             16989..17258
                     /locus_tag="ACL8JK_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGS1786563.1"
                     /translation="MKLDEKIALVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALICGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            17262..17621
                     /locus_tag="ACL8JK_001720"
     CDS             17262..17621
                     /locus_tag="ACL8JK_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HGS1786564.1"
                     /translation="MAGSSREHAAWVLADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPIDQATVDLEQQKIISPVEEFTFEIDSEWKHKLLNTLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17783..18353
                     /locus_tag="ACL8JK_001721"
                     /pseudo
     CDS             17783..18353
                     /locus_tag="ACL8JK_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004915491.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            18447..18512
                     /locus_tag="ACL8JK_001722"
                     /pseudo
     CDS             18447..18512
                     /locus_tag="ACL8JK_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            18675..>19679
                     /locus_tag="ACL8JK_001723"
     CDS             18675..>19679
                     /locus_tag="ACL8JK_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS1786565.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     T"
BASE COUNT         6218 a         3332 c         4157 g         5972 t
ORIGIN      
        1 aaaaaccttg atatgatgcg ttttattgtg ggaatatgta tttcattttc tactaaaatt
       61 atgtttttga ataacctcta tcttagtagt ttgtataatc cccctcaatc agtttttgcg
      121 ataagcttta atgctatgac tataccactc ttgcatttct tttgatggtg gtgttatata
      181 atcgccatac atctgggtta aaaattggtc atattttttg ggaacaggca acatacggcc
      241 ctcaaactca gttaaaatca gttctttaaa ggtatcaact gggaagattt ctttcatccc
      301 ttccttaccg atcccaactc ctccttcata ttgaggagtg ttggttacag catttttgac
      361 tagttgatca attttcttgt aaaagtagcg aggattgaca aaccggagag cgtaccagct
      421 acataatcta agaaaatctt ttagtttgct atcaccgtga actgctcgtg attttttgat
      481 ataagctagt tgacgaaggg ctacatactt atagctcttg tcgacaatgc tcaagtctgt
      541 aaatcgatca attgggaaga catcgatgaa aaggctggta tcatgacgct tgtacttaac
      601 atggtcttct ataacagtag aagtgtccaa aatcgatgcg aaattatgga agtaccaaga
      661 agatgtatcg taggaaagaa ccttgtagcg agggtgattt tcttcttcaa taatcttcag
      721 taaacgctca taatcctcac gataaaggga aatatcaata tcatcatccc aaggaatcat
      781 acctttgtgg cggatggctc caagcatggt tccataactg agaaaataag gaatatcatg
      841 tttcttacaa gtctcatcaa tatagtccag cagggctagt tgaatttctt taatttcttt
      901 tttttctaaa tattgcatcc taatcctcca atttataagc gtgaaattca tgactgtaga
      961 agcgtttttc ttctggtggt agggtcatat aatctccata aaattgtgtc aaaatagtat
     1021 caaatttttc aggtgcagga aggcttaaat tctcaaaggg taaatcgatt gttttatcaa
     1081 aggtaccact tgggaagact tccttttcct taaattttga aggaataaaa gccatatact
     1141 gcccattttc acgactatat ttttgaattt ctttctcgat tttatttgca aaataacgag
     1201 gagaaaccgg tcgaaggagc aaccaaaagg ctgttcgtat ccaatctttt aaaaggctat
     1261 ccttatagac aatattttta tgtttactga aagacagcag tttgaagctt tccagtttat
     1321 aacaagtatc aatgacctta ggatcatcaa agcgatctat agggaaaata tcgataaaga
     1381 taccagactc ataggttttt gtatttcgag tatcaataat tttagtcgta ctgtcggtta
     1441 tcttgataaa gttgttaaag tagttcttat cagtttctaa ggataggagc ttatacttgc
     1501 ttttttcctt ttgaaaaatg ttaataaatc gttggtagtc ttctctaggc atggataaat
     1561 caatatcgtc gtcccaaggg ataaagccct catgtcgaac cgccccaatc agagtaccgt
     1621 agttaataat atagttgata ttgtgctttt tacagagagt atcaatataa tccaaaattt
     1681 ctaattcaat ttgtttggca tcttcaacgg ttagttgttt cattttaaac tcctatgatt
     1741 ttttaaattt attttttaag gctagaacat ggtttaaaaa ttcatagaaa atgctatctt
     1801 ttgtgaagac aagtagacta atataagaga tagctgatag caagataatc aaaccagtat
     1861 taatcaaaaa tggcaaatta atgaccatat ccacaggata cacgaaatta atcaggaaat
     1921 aaattgctac aaaggaaagt gaaaagagag agtatcgaac agtatagcta aagatatgtc
     1981 ccaagtggat gagttgtttt ctatggatga aaatgatata gaaaacaagt agagaagcct
     2041 ctgataacat agttgtcagt aagtagtatt cgggagccac gatacggttg aaaaagagga
     2101 gactattcaa gcccaaattg agtagcccag caaagactgt ataaactgtg atacgttttt
     2161 catagccatt ggtaaagaga atttgggaac caagaatggt atctaaggcc aggataatcg
     2221 tacgaaaagc gaagagagag gtcaagatgc cgcctccgat atatttttca ctaccgtaaa
     2281 gtaggatggc atttggtcct aaaaccatga gtccaaaact cagtggaatg ataaagaagt
     2341 taaagattcg actacctcta ttaaccagag aaacataggc ttctttgtct cctttcccca
     2401 gatagtaact gagacgaggc acactcactc caattgcacc tgttacaacc ccagctataa
     2461 cggtcacaat tcgctgagct atggtatagt aactaacgtt gacatcaatc cctgttttaa
     2521 cgaggaagag gcgatctaaa aaagtgaaga gcatattggc attggcaaag actaacatgg
     2581 ctgtcagagg gagaaagagt ggtttaaaat cacttaggtg aatcttaaca agtttgatgt
     2641 ctcttttaat ccaaaaataa ctaatcaggt agttaatcag cgtcgataaa ctcatcacaa
     2701 gtgtatagac aacaatatcg tgttcatttt taacaaataa gaaaatagag accagcatca
     2761 ggatacggat gaaggcagtt ttgtaaaaga gaaaactgta attttccaga gcttcattga
     2821 cccattcgat tgaaaaaatc tgggcaatga gttgaatccc cataacaagg tagacctttt
     2881 tgacgattgg attatcagta aagaagagag gataggctag gatatagaca gcagtggtca
     2941 aaatcgtaca agcgatgcac aaataaaaaa gactagaaaa ggttctgtta agatcttttt
     3001 tgttatcctt gacattactg atagccctta aaccgtagct atagacacca taagttgcaa
     3061 agggcaagaa aaatgacaaa atagtgtcga ctgagttgaa gtaaccatag tcagttcggt
     3121 ccaagacacg cgcgacatag gttccagtta ggatgggaaa aataatattc aagacacgaa
     3181 ttcccatgta agatagagca tttaatttta tacttttcat tcaatttacc tcgtttttca
     3241 ttatatcata aagttagcta ataagaaatg aagggcagta agccaagcaa tcactttgaa
     3301 gtttcaaatc ttaaatttta agttttcttt aaggaaagta tattattctg aaggactcta
     3361 aaatttcgca gtcatttatt agtaattgct acagaattcc tagtcattac tagaaatgga
     3421 ctagtttctt tgaataatag aactgcataa ttctcctatt ctagaagggg aggaccagta
     3481 tttcttttat gataggacta gattgtggta taatagagag aataagtttt tttagtaaga
     3541 caaaggagaa aatagatgat ttatgcagga attcttgccg gtggaactgg cacacgcatg
     3601 gggatcagta acttgccaaa acaattttta gagctaggtg atcgacctat tttgattcat
     3661 acaattgaaa aatttgtctt ggagccaagt attgaaaaaa ttgtagttgg tgttcatgga
     3721 gactgggttt ctcatgcaga agatcttgta gataaatatc ttcctcttta taaggaacgt
     3781 atcatcatta caaagggtgg tgctgaccgc aatacaagta ttgagaacat cattgaagcc
     3841 attgatgctt atcgtccgct tacttcagag gatatcgttg ttacccacga ttctgttcgt
     3901 ccatttatta cacttcgcat gattcaggac aatatccaac ttgcccaaaa tcatgacgca
     3961 gtggacacag tggtagaagc agtggatact atcgttgaaa gtaccaatgg gcaattcatt
     4021 acaggtattc caaatcgtgc tcacctctat cagggacaaa cacctcaaac attccgttgc
     4081 aaggacttca tggaccttta tggatctctt tctgatgaag agaaggaaat cttgacagat
     4141 gcatgtaaaa tctttgtgat caaaggaaaa gatgtggcct tggccaaagg tgaatactca
     4201 aatctgaaga ttacaaccgt aacagatttg aagattgcaa aaagtatgat tgagaaagac
     4261 tagtaaaatg attaatcaaa tttatcaact aactaagcct aagtttatca atgtcaaata
     4321 tcaggaagag gctattgacc aagagaatca tatccttatc cgtcccaact acatggctgt
     4381 ctgtcatgcg gatcagcgtt actatcaggg aaaacgtgat cccaagattt tgaataaaaa
     4441 gcttccaatg gcaatgattc acgagtcatg tggaaccgtc atttctgacc cgaccggaac
     4501 ctacgaggtt ggtcaaaaag ttgtcatgat tcccaatcag tctcctatgc agagtgatga
     4561 agaattctat gaaaactaca tgacagggac ccatttcttg tctagtggat ttgatggctt
     4621 tatgagagag tttgtttctc tccctaaaga tcgtgtggtg gcttatgatg ctattgaaga
     4681 tacggttgca gccattacag agtttgtcag tgtgggcatg cacgctatga atcgtctatt
     4741 gactcttgct catagcaagc gggagcggat cgccgttatt ggagatggaa gtttagcttt
     4801 tgtggttgcc aatattatca actatacttt gccagaatca gagattgtgg ttattggtcg
     4861 tcattgggaa aagttggaac tcttctcatt tgccaaagaa tgctatatta cggataatat
     4921 tcctgaagat ttggcctttg accatgcttt tgaatgttgt ggtggtgatg gtactggacc
     4981 agctattaat gacttgattc gctacattcg tcctcaggga acgattctca tgatgggagt
     5041 tagcgaatat aaagtcaatc tcaatactcg cgatgcctta gaaaagggct tgattttggt
     5101 tgggtcatct cgttctggtc gcattgattt tgaaaatgct atccaaatga tggaagtcaa
     5161 gaaatttgcc aatcgtctta aaaatatcct ttatctagaa gaacctgtaa gagaaattaa
     5221 agatattcat cgtgtctttg caaccgattt aaacacagcc tttaaaacag tgtttaagtg
     5281 ggaagtataa gtactggagg ttaattgtgg agaaaatcat taaagaaaaa atttcttcct
     5341 tacttagtca agaagaggaa gtcctcagtg ttgaacaact gggtggaatg accaatcaaa
     5401 actatttggc caaaacaaca aataagcaat acattgttaa attctttggt aaagggacag
     5461 aaaagcttat caatcgacaa gatgaaaagt acaatcttga actactaaag gatttaggct
     5521 tagatgtaaa aaattatctt tttgatattg aagctggtat caaagtaaat gagtatatcg
     5581 aatctgctat tacgcttgat gcgacttcaa ttaagaccaa atttgataaa attgttccaa
     5641 tattacaaac tattcatgct tctggcaagg aattaagagg agaatttgct ccttttgaag
     5701 aaatcaaaaa atatgaatcc ttaattgaag agaaaatccc ttatgccaac tatgaagctg
     5761 ttcgagaaga agtcttctcc ttagagaaaa gactggctga cttaggtgtt tacagaaaat
     5821 cttgtcatat cgatttggtg cctgaaaact ttatcgaatc acctcaagga cgactttatt
     5881 tgattgactg ggaatattca tcaatgaatg atccaatgtg ggatttggct gccctctttt
     5941 tagagtctga attcacttcc caagaggaag aaactttctt atctcactat gagagtgacc
     6001 aaacaccggt ttctcatgaa aagattgcta tttataaaat tttacaagat actatttgga
     6061 gtctatggac tgtctataag gaagagcaag gtgcagattt tggttactat ggtgtgaatc
     6121 gttaccaaag agctgttaaa ggtttggctt cttatggagg ttcagatgaa aagtaaaaac
     6181 ggagttcctt ttggccttct ctcaggtatt ttctggggct tgggtctaac ggttagtgct
     6241 tatatctttt cgatttttac agatttgtca ccctttgtgg tggctgcagc tcatgatttt
     6301 ttgagcatct ttatcttact agcttttctc ttggtaaaag aagggaaagt tcgcctctca
     6361 attttcttaa atattcgcaa tgtcagtgtt atcatcggag ccttgctagc aggccctatc
     6421 ggtatgcagg ccaatcttta tgcagttaag tatatcggaa gttctttagc ttcatctgta
     6481 tcggctattt accctgcgat ttcagttcta ttggctttct tctttttgaa gcacaagatt
     6541 tcgaaaaata ctgtatttgg gattgtcttg attattggag ggattattgc ccagacctat
     6601 aaggttgaac aggttaattc tttctacatt gggattcttt gtgctttggt ttgtgctatt
     6661 gcatggggaa gtgagagtgt tcttagctct tttgccatgg aaagtgaatt gagtgaaatc
     6721 gaagccctct taatccgtca agtaacttcg ttcttgtcct atcttgtgat tgtgctcttc
     6781 tctcatcagt catttactgc agtagccaat ggacaattgc taggtctcat gattgttttt
     6841 gcagcctttg atatgatttc ctacttggct tattatatcg ctatcaatcg cttgcaacca
     6901 gccaaggcta caggcttgaa cgtgagctat gtagtatgga cggtcttgtt tgcagttgtt
     6961 ttcttgggtg caccgctaga tatgctgacc attatgacgt cacttgtcgt cattgctgga
     7021 gtttatatta ttattaaaga ataaaggaga ttcgtgtgaa agccattatc ttagcagcgg
     7081 gattgggaac tcgcttgcgt cctatgactg aaaatacccc taaagccttg gttcaggtta
     7141 atcaaaaacc cttaattgag taccaaattg agtttctcaa agaaaaagga atcaatgaca
     7201 tcatcatcat tgttggttat cttaaagaac aattcgatta cttgaaagag aaatacggtg
     7261 ttcgtctcgt tttcaatgat aaatacgctg actacaataa cttttactct ctctatcttg
     7321 taaaagaaga attggccaac agctatgtta ttgatgcaga taactatctc tttaaaaata
     7381 tgttccgcaa tgatttgact cgttcgactt attttagtgt ttatcgtgaa gattgtacca
     7441 acgaatggtt cttggtctat ggagatgact acaaggttca agacattatt gttgatagca
     7501 aggcaggtcg catccttagt ggtgtatcct tctgggatgc tccaactgca gaaaagattg
     7561 tcagctttat cgataaggct tatgcaagtg gcgaatttgt tgatctctac tgggacaata
     7621 tggttaagga taatatcaaa gagctagatg tctatgttga agaattagaa ggcaatagca
     7681 tttatgagat cgatagtgtc caagactatc gtaaattaga agaaattctt aaaaacgaaa
     7741 attaaagatt ccaacatctg acaaaatagt cggatgtttt ttgatttttt acgaactttt
     7801 acgaatagat agatgagtag aaaaagaaat ggagttattt atgaaaatca caaactatga
     7861 aatctataag ttaaaaaaat caggtttgac caatcaacag attttgaaag tgctagaata
     7921 cggtgaaaat gttgatcagg agcttttgtt gggtgatatt gcagatatat caggttgccg
     7981 taatccagcc gtttttatgg aacgttattt tcagatagac gatgcgcatt tgtcgaaaga
     8041 gtttcaaaaa tttccatctt tctctatttt agatgactgt tatccttggg atttgagtga
     8101 aatatatgat gcgcctgtac ttttatttta caagggaaat cttgacctcc tgaaattccc
     8161 gaaggtagcg gtcgtgggca gtcgtgcttg tagcaaacag ggagctaaat cagttgaaaa
     8221 agtcattcaa ggcttggaaa atgaactggt tattgtcagt ggtctggcca agggcattga
     8281 cacagcagct catatggcag ctcttcagaa tggcggaaaa accattgcag tgattggaac
     8341 aggactggat gtgttttatc ctaaagccaa taaacgcttg caagactaca tcggcaatga
     8401 ccatctggtt ttaagtgaat atggacctgg cgaacaacct ctgaaatttc attttcctgc
     8461 ccgtaatcgc atcattgctg gactttgtcg tggtgtgatt gtagcagagg ctaagatgcg
     8521 ttcaggtagt ctcattacgt gtgagcgagc aatggaagaa ggacgcgatg tctttgctat
     8581 tcctgctagc attttagatg gactatcaga cggttgccat catttgattc aagaaggagc
     8641 aaaattggtc accagtgggc aagatgttct tgcggaattt gaattttaaa aatgacctaa
     8701 gctagaattc taagaaaaaa tcaattttaa gagaaaatga acccaacatt tccataataa
     8761 aacgcatatt agcaagtttt taacacttga taatatgcgt tttttctaag tggattagta
     8821 gagtagagga tttttctcat ataatactct tcgaaaatct cttcaaacta cgtcagcttc
     8881 catctgcaac ctcaaaacag tattttgagc aacctgtggc tcgcttccta gtttgcgctt
     8941 tgattttcat tgagtataag ggaaagtata gtgaattgaa ataagatgtg aacaactcta
     9001 tcaggaaagt caaattaatt tatagaaata ttttagcagc caaggtgcac tgttatagat
     9061 tcaatacaca ataatttagt gtaattgaga aaggagaaat gattgtgatt gatgttggct
     9121 aggttatgtt caatgattcc taccgtctca aatcttgtca gtaaggaaaa ataaattctt
     9181 caaaagtaga gattacaagg cttgtttaag aaagaattca aagaccttga caaataaaaa
     9241 taaaatggtt attataaaaa atggtctgaa atagatgatg atacttttcg aaaatctttt
     9301 tacgtcagct cagctttgcc ttgctgtgtt ttgagcaagc tacggttagc ttccgagttt
     9361 gattttcatt tactagaaat gaaactgatg agagatatca gtagacatct gagttaggat
     9421 attatggaaa atgataaaaa gagctcgtga gattggcata tcagactact aaagtattga
     9481 gtttgttagg attttagcga ctagttagct gggaaaggaa gatatttgtg acaaataata
     9541 aactgtattc gttgatagaa tttagaaata aaatatatga agaattagaa ctttccagaa
     9601 gtgatttagc gattttacta tgtgccatgc ttatcgcctc tatcggatta aatatggatt
     9661 cgactcccgt gattattgga gccatgttaa tctctccttt gatgacacct attctgggag
     9721 tggggctctc tctagctata tttgatttta aattgttaag aaaatctttt aaaatattag
     9781 ctattcaaat tcttgccagt ctaatagctt caacacttta tttttatctt tctcccattt
     9841 cgtatgctag ttcggagatt gttgctagaa cctctccgac tatttgggat gttctcattg
     9901 cttttgtagg agggatagca ggtattattg gtgctaggaa aaaagagacc aataatattg
     9961 ttcctggtgt tgctattgca accgccttga tgcctcctct ttgtacagta ggttatgcta
    10021 ttgcttctgc taatctaaaa tttatcatag gctcctctta cctattcctc atcaattgta
    10081 gctttattgt cattgcgact tatataggtg ttaggttgat gatggttaag aaacattatt
    10141 ttaaagataa tgaagaagac tctaaaatgc gtaggatttt gcttctagtt gctgttttgc
    10201 tgatgattcc gagtttcatc tctgcaacga ctttagtgag agaaacgttg aaaaaagagt
    10261 cccttaagaa atttatatca gagcagtttc aggggtataa tattttgaaa aaaacctatt
    10321 ctaaaaagac tcatacccta aagctaacca tttcaggaaa ttatttgaca gaagaagaac
    10381 tcgatatgat ttcaagtaag agaggtgact atggtttaag tgatgtttct gttcaagttt
    10441 cacaattgtc tgattcagaa caacttagta aggaagagct ggtggagtat ttcttccagt
    10501 atatcaagga taaggaagca aaagaaaagg agaaagctaa taaatttgat acagagtctg
    10561 aggagcaata atttcttgag aatagctggt ttctctcgtg agtcttctat gtatatcaaa
    10621 ggaagactga ggttttaagt ataaaacttt tcttctatta tagtagctaa gtcttgacag
    10681 ggttcaaaaa atggtttaca ctttataaag tttattactt tgaaaaggtg tgatactgtg
    10741 gctacggcaa caaaaaagaa aaaatcaaca gttaaaaaaa atctagtcat cgtggagtcg
    10801 cctgctaagg ccaagacgat tgaaaaatat ctaggcagaa actacaaggt tttagccagt
    10861 gtcgggcata tccgtgattt gaagaaatcc agtatgtccg tcgatattga aaataattat
    10921 gaaccgcaat atatcaatat ccgaggaaaa ggccctctta tcaatgactt gaaaaaagaa
    10981 gctaaaaaag ctaataaagt ttttctcgcg agtgacccgg accgtgaagg agaagcgatt
    11041 tcttggcatt tggcccatat tctcaacttg gatgaaaatg atgccaaccg tgtggtcttc
    11101 aatgaaatca ccaaggatgc agtcaaaaat gcttttaaag aacctcgtaa gatcgatatg
    11161 gacttggtcg atgcccaaca agctcgtcgg atcttggatc gcttggtagg gtattcgatt
    11221 tcgcctattt tgtggaagaa ggtcaagaag ggcttgtcag caggtcgcgt tcagtccatt
    11281 gcccttaaac tcatcattga ccgtgaaaat gaaatcaatg ccttccagcc agaagaatac
    11341 tggacagttg atgctgtctt taaaaaggga accaaacaat ttcatgcttc cttctatgga
    11401 gtagatggta aaaagatgaa actgaccagc aatgacgaag tcaaggaagt cttgtctcgt
    11461 ctgacgagta aagacttttc agtagatcag gtggataaga aagagcgcaa gcgcaatgct
    11521 cctttaccct ataccacttc atctatgcag atggatgctg ccaataaaat caatttccgt
    11581 actcgaaaaa ccatgatggt tgcccaacag ctctatgaag gaattaatat cggttctggt
    11641 gttcaaggtt tgattaccta tatgcgtacc gattcgactc gtatcagtcc tgtagcgcaa
    11701 aatgaggcgg caagcttcat tacggatcgt tttggtagta agtattctaa gcacggtagc
    11761 aaggtcaaaa atgcatcagg tgctcaggat gcccatgagg ctattcgtcc gtcaagtgtc
    11821 tttaatacac cagaaagcat cgctaagtat ctggacaagg atcagctcaa gctatatacc
    11881 cttatctgga atcgttttgt ggctagccag atgacagcgg ccgtttttga taccatggct
    11941 gttaaattgt ctcaaaatgg agttcaattt gctgccaatg gtagtcaggt taagtttgat
    12001 ggttatcttg ccatttataa tgattctgac aagaataaga tgttaccgga catggttgtt
    12061 ggagatgtgg tcaaacaggt caatagcaaa ccagagcaac atttcaccca accgcctgcc
    12121 cgttattctg aagcaacact gattaaaacc ttagaggaaa atggggttgg acgtccatca
    12181 acctatgcgc caaccattga aaccattcag aaacgttatt atgttcgcct ggcagccaaa
    12241 cgttttgaac cgacagagtt gggagaaatt gtcaataagc tcatcgttga atatttccca
    12301 gatatcgtaa acgtgacctt cacagctgaa atggaaggta aactggatga tgtcgaagtt
    12361 ggaaaagagc agtggcgacg ggtcattgat gccttttaca aaccattctc taaagaagtt
    12421 gccaaggctg aagaagaaat ggaaaaaatc cagattaagg atgaaccagc tggatttgac
    12481 tgtgaagtgt gtggcagtcc aatggtcatt aaacttggtc gttttggtaa attctacgct
    12541 tgtagcaatt tcccagattg ccgtcatacc caagcaatcg tgaaagagat tggtgttgag
    12601 tgtccaagct gtcatcaggg acaaattatt gagcgaaaaa ccaagcgtaa tcgcctcttc
    12661 tatggttgca atcgctatcc agaatgtgaa tttacctctt gggacaagcc tgttggtcgt
    12721 gactgtccaa aatgtggcaa cttcctcatg gagaaaaaag tccgtggtgg tggcaagcag
    12781 gttgtttgta gcaaaggcga ctacgaggaa gaaaagatta aataagagga ggggcccgaa
    12841 agtaaatttc aggctccttt tggttagaac ttgacaaaat acatcatttt atgcgaaact
    12901 agaagaagat tattttatac tcaatgagaa tcaaagagca aattagaaag ctagtcgcag
    12961 gttgctcaaa gcactacttt gaggttgaag atggaagctg acctggtttg aagagatttt
    13021 cgaagagtat taactaggag aagttatgcg tcttatctat ctgataattg gttttttatc
    13081 actggccttg gctattgttg gggttgtttt acccttgttg ccgacaacac ctttcctttt
    13141 gttgtctatt gcttgtttct ccagaagttc caagcgattc gaagattggc tttatcatac
    13201 caagctctat caagcatatg tagctgattt tcgtgagacc aagtctattg cgcgtgaacg
    13261 aaagaaaaaa atcatcgtct ctatctacgt cttgatggga atttctattt attttgcacc
    13321 tcttttacca gtcaaaatcg gtctgggtgc tttgaccatc tttattactt attatctctt
    13381 caaggtcatt ccagacaaag aatagttaaa acagtagtta tttgccttga taaaattgaa
    13441 agcatattca taacaatatg atataataaa attgaagtaa tattcaagga gaatcaaatg
    13501 atttacgaat tttgtgctga aaatgtgact ttacttgaaa aagcgatgca ggctggagct
    13561 cgtcggattg aactctgtga taatctagca gttggtggga caacacccag ctatggagtg
    13621 actaaggcag cggttgaact ggcagctaac tacgatacaa ccatcatgac catgattcgg
    13681 ccacgtggtg gtgactttgt ctataatgac ctagaaattg ctatcatgct agaagacatt
    13741 cgtttgactg ctcaggctgg aagtcaaggg gttgtatttg gagctttaac tgctgataaa
    13801 aagttggata agcctaatct ggaaaagtta attgctgcat caaaaggaat ggaaattgtc
    13861 tttcacatgg cctttgatga actaagtgat gaagatcaac cggaagctat tgactggctc
    13921 agtcaagccg gtgtcactcg tatcctaact cgtgctggtg tgtctggcga ctccttagaa
    13981 aaacgttttg ttcactatca cagaattttg aagtacgcta aaggtaaaat tgaaattcta
    14041 ccaggtgggg ggattgacct tgaaaaccgt caaaccttta tcgaccaggt gggggtaaca
    14101 caattgcatg gtactaaggt tgttttttaa aaaatagaaa ggaactgcta gctttgggta
    14161 gcagttttca cttatgtttg aaatttttaa atcctatcaa tttaatcaag aaaaggctca
    14221 tgattatggt tttatagaaa atagcgaagt ctggacatat agttgccaga ttttgcaagg
    14281 tgactttgtc atgactgtgt ccatcactgc tgataatgtg aactttcaag tctttgacca
    14341 agagactggt gacctctatc ctcacgttta tatggaaagc atgaggggaa gttttgtcgg
    14401 aaatgtccgt gaggcttgtc tggagattct ttaccagatt cggaaggctt gttttgatgt
    14461 gcaagatttt atctgtcatc agactaagcg tatcatgact caagttcagg aaaagtatgg
    14521 aaaccagttg gagtatctgt gggaaaaatc gcctgataca gctgtattgc gccatgaagg
    14581 caatcaaaag tggtatgccg tcttgatgaa aatctcttgg aataagctgg aaaagggcag
    14641 agaaggacaa gtggaagcag tcaacctcaa gcatgaccaa gtagctaatt tgctttcaca
    14701 aaaggggatt tatccagcct tccatatgag caagcgctac tggattagtg tgtcccttga
    14761 tgatacttta tcagatgaag aagtactgga attgatagaa aaaagttgga acttaacctc
    14821 taaaaaatga aatattttaa taattttcat gaactttcaa ttagctaaat attctttact
    14881 gaagaaattt tcagaaaata taggatttac cacaccagag gaatgtggtg ccatcttcaa
    14941 atacctgatt gagaatgtca agacggatcg tcagatcatc tattcgcctc actgtcatga
    15001 tgacctcgga atggcagtgg caaatagcct tgctgctgtc aagaatggtg caggacgtgt
    15061 tgaagggact atcaatggta ttagggagcg agctgaaaat gctgctttgg aagaaattgc
    15121 agtggctctc aatattcgcc aagattacta ccaagtagaa accagtattg tcctaaatga
    15181 gaccatcaat acgtcagaaa tggtttctcg cttctctggt attccagttc ctaaaaacaa
    15241 agccgtcgtt ggtggcaata ccttctccca cgaatctggt attcaccaag atggagtcct
    15301 taaaaatcct ctcacttatg agatcatcac acctgaattg gttggtgtta agattccgct
    15361 tggaaaatta tctggtcgcc atgcttttgt tgagaaactg agagaattgg ccctagattt
    15421 tacagaagag gatatcaaac cactctttgc taagttcaag gcactggccg ataagaagta
    15481 agaaatcaca gatgcagata ctcgagcttt ggtagctgga accatggttg aaaatccaga
    15541 aggcttccac tttgatgatt tacaacttca aactcatgca gataatgaca ttgaagcgct
    15601 cgttagccta gccaatatgg atggtgagaa agtcgaattt aatgcgacag ggcaaggttc
    15661 cgttgaagca atctttaacg ctatcgataa gttctttaac caatctgttc gtttggtgtc
    15721 ctacactatc aatgcggtaa cagatggaat cgatgcccag gatcgggttt tggtcactgt
    15781 tgaaaacaga gatacagaaa ccatctttaa tgcagcaggg cttgattttg atgtgttgaa
    15841 ggcttctgct attgtctata taaacgctaa tacctttgtt caaaaagaga atgcaggtga
    15901 gatgggacgc agtgtttctt accacgatat gcctagtgtg taaaggagaa ggctatggca
    15961 aagaaaatag tagctctagc aggagacgga attggcccag aaatcatgga ggctggttta
    16021 gaagttctgg aggctctagc tgaaaaaaca ggttttgact atgagattga cagacgaccg
    16081 ttcggaggtg cagatattga tgcagcaggg cctcccttac ctgatgaaac ccttaaggca
    16141 agtagggaag cagatgctat cctactagca gctatcggta gtcctcagta tgatggagca
    16201 gtggttcgcc ctgaacaagg cctgatggct ctccgtaagg aactcaatct ttacgctaat
    16261 attcgtcctg taaaaatctt tgacagtctc aagcatttgt caccactcaa actggaacga
    16321 attgctggtg tagactttgt cgtggtgcgt gaattgacag gcgggattta ctttggagat
    16381 tatattcttg aagagcgcaa tgcgcgtgat atcaacgact atagctatga ggaagtggag
    16441 cggattattc gcaaagcctt tgaaattgca agaaatcgca gaaaaatcgt tactagtatc
    16501 gataagcaaa atgttctagc gacctcaaaa ctctggcgga aagtagctga ggaagtcgca
    16561 caggatttcc cagatgtaac cttggaacac cagctggtag actcagctgc tatgcttatg
    16621 attaccaatc ctgctaagtt tgatgttatt gtaacggaga atctttttgg agatatttta
    16681 tctgatgaat caagcgtctt atctggtaca cttgaggtta tgccatcagc cagtcattct
    16741 gaaaatggac caagtctcta tgaacctatt cacggttcag cacctgatat tgcaggtcaa
    16801 ggaattgcca atcctacttc catgatttta tcagttgcca tgatgttgag agatagtttc
    16861 ggacgttatg aggatgcaga gcgtatcaaa cgtgctgttg agacaagtct ggcggcagga
    16921 attttaacga gagatatagg aggtcaggct tcaacaaagg aaatgacgga agctattatt
    16981 gcaaggttat gaagttagac gaaaaaattg ctctagtcct tttgatttgg aatgtcatca
    17041 ttttcttgat ttatggcatt gacaaattca aggcaaggag aagagcttgg cgcatccaag
    17101 agaaaatctt actcatttta gcccttattt gtggtggttt tggggcctgg ttagctggaa
    17161 tcacttttca ccacaagact cgaaaatggt actttaaaac agtttggttt cttgggatgg
    17221 tgaccacact agtagcctta tattttattt ggaggtaatg gatggcaggg tcttcgaggg
    17281 aacacgctgc ttgggttcta gcggactatg gttttaaggt cgtgattgca ggatctttcg
    17341 gtgacattca ttacaataat gaactcaata atggcctgtt gccaatcgtt cagcctagag
    17401 aggttagaga gaaattagcc cagctaaaac caatcgacca ggcaactgtg gacttggaac
    17461 aacaaaaaat catctcacca gttgaagaat tcaccttcga gatagatagc gagtggaaac
    17521 ataaactcct aaatactttg gatgatatcg gtattacctt gcagtatgaa gagttgattg
    17581 ctgcttatga aaaacaacga ccagcctact ggcaggatta gaaaaaatag aaaaggaaat
    17641 atagtaaact gaaataagat gtaaacaaat gaattagagc ttaacatcca tttccagcaa
    17701 ttttttagaa actacagtgg actattctgg attcaacaca ttataaaatt atgacaaaac
    17761 acattcacaa gaaggctacg acattttaaa aggtgagggc ggatgtatcg tttgccctac
    17821 taaagttggt tacattatca tgaccagtga caaggcagga cttgagcgta agttcgcagc
    17881 caaagaacgt aagcgtaaca aaccaggtgt tgttctctgc ggtagcatgg atgaacttcg
    17941 cgctttagcg caactcaacc cagaaattga agcattctac taaaaacatt gggatgaaga
    18001 tattcttctt ggttgtatcc ttccttggaa accagaagcc tctgaaaaac tcaaagcata
    18061 cggggatggc cgtgaagaac ttatgactga tgtacgtggt actagctgtt ttgttatcaa
    18121 gtttggaaaa gcaggtgaac aattggctgc caagctttgg gaagaaggta aaatggtcta
    18181 cgcctcatct gcttcaatga caaaacgatt gaaactcgct atgagagcaa ggtgtaatgg
    18241 tgtctatggt cgataaggac ggcaaactca tcccagaaca aggaggagca cgttcaactt
    18301 caccagcacc agttgtgatc cgtaaagggc ttgacattga tatagtaaaa tgaagtaaga
    18361 gcaggacaaa ttaatcagga cagtcaaatc gatttctaac aatgttttag aagtagaggt
    18421 gtactattct agtttcaatc cactataaaa tcatgatgca cctgtcagat acttttaact
    18481 catgggacta ccgtcaggtt gagtattatt aggatagaga agaagtctag tgttaaggac
    18541 attacagctc ataatactag gcttttttat agaaattctt ttctttttct ataggatatg
    18601 gtattctatg tagaaaatat atgttaataa gtaatgccaa tatttaaaca tcattagtaa
    18661 aaggagttag attgatgaat aaaagaaaag ttagtttaga agatttttat aaatggtata
    18721 gtctaaataa agaagagtta ttaaataagg caactgttgg tgaaaagttt aatgataaat
    18781 taaaagaaga gtttctccag gaatggcctt tggataggat tttaacaatg tcaatcgatg
    18841 aatatgtaat aggaaaggga cagcaaaata agtctttatg ctacgctctt gagaagggaa
    18901 aatacaaaaa tctatttctt ggaatttctg gtggctcagc ttcaaaattt ggtatttatt
    18961 ggaataaaaa aacaaacaaa tataaagatc aagctaataa tgagatttca gagttggatc
    19021 agcgattttc aaaattaaaa tcagatttgt atgaaattat caaagaaggt attcgtttta
    19081 actttgaaaa tcctattttt gatatgaaaa gatcaacaaa tgaatttatt ggtcgttctg
    19141 ctatggtgac aaaattactt tgtatctatt ctgagggaga tcctttcttt ggtgtaaata
    19201 ttaatagtca gaaagaattt tggaaccact ttgtttctca gacaaatcaa ggtggacctt
    19261 atctgcaaaa tcataaaata attgaactgg tgtccaaaac ttatcctgag ttggagccat
    19321 cgaaattagg aactatgctt tttgagtatt ctaagctttt tatggaaaat aaggaagaca
    19381 atagtacaat ggattcatca aacaattttc gtcatcaatt aactcaatct ctattaaagt
    19441 ctccaaacct tatccttcgt ggtgctcctg gcacaggaaa gacttatctt gctaaagaaa
    19501 ttgccaaaga attaacggat ggcaacgaag accaaatcgg atttgtacaa tttcacccat
    19561 catatgatta tacggatttt gtagaaggtt taagaccagt atcaaatggg gatggagcta
    19621 ttgagtttag gctacaggac ggtattttta aagatttttg tcagaaagca aaagaaacc
//
LOCUS       DBERXF010000043        19591 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.43, whole genome shotgun sequence.
ACCESSION   DBERXF010000043 DBERXF010000000
VERSION     DBERXF010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19591
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.43"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(23..670)
                     /locus_tag="ACL8JK_001724"
     CDS             complement(23..670)
                     /locus_tag="ACL8JK_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HGS1786566.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(779..1298)
                     /locus_tag="ACL8JK_001725"
                     /pseudo
     CDS             complement(779..1298)
                     /locus_tag="ACL8JK_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
     gene            complement(1335..1463)
                     /locus_tag="ACL8JK_001726"
                     /pseudo
     CDS             complement(1335..1463)
                     /locus_tag="ACL8JK_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
     gene            complement(1525..2394)
                     /gene="rsmI"
                     /locus_tag="ACL8JK_001727"
     CDS             complement(1525..2394)
                     /gene="rsmI"
                     /locus_tag="ACL8JK_001727"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGS1786567.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2397..2714)
                     /gene="yabA"
                     /locus_tag="ACL8JK_001728"
     CDS             complement(2397..2714)
                     /gene="yabA"
                     /locus_tag="ACL8JK_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGS1786568.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2754..3644)
                     /locus_tag="ACL8JK_001729"
     CDS             complement(2754..3644)
                     /locus_tag="ACL8JK_001729"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGS1786569.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3641..4279)
                     /gene="tmk"
                     /locus_tag="ACL8JK_001730"
     CDS             complement(3641..4279)
                     /gene="tmk"
                     /locus_tag="ACL8JK_001730"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGS1786570.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4499..5296)
                     /gene="proC"
                     /locus_tag="ACL8JK_001731"
     CDS             complement(4499..5296)
                     /gene="proC"
                     /locus_tag="ACL8JK_001731"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGS1786571.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFYQLLAKAGLLVELGES
                     LIDAATGLAGCGPAFVYLFIEALADAGVQTGLPREIALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(5300..6562)
                     /locus_tag="ACL8JK_001732"
     CDS             complement(5300..6562)
                     /locus_tag="ACL8JK_001732"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGS1786572.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(6572..7681)
                     /gene="proB"
                     /locus_tag="ACL8JK_001733"
     CDS             complement(6572..7681)
                     /gene="proB"
                     /locus_tag="ACL8JK_001733"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGS1786573.1"
                     /translation="MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHEL
                     ILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILL
                     TQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSAQVAAMVQ
                     ADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIK
                     AATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQG
                     SIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKGRVQFGAS
                     ALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7782..9665)
                     /gene="cbpE"
                     /locus_tag="ACL8JK_001734"
                     /gene_synonym="pce"
     CDS             complement(7782..9665)
                     /gene="cbpE"
                     /locus_tag="ACL8JK_001734"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HGS1786574.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIAGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(9668..10555)
                     /locus_tag="ACL8JK_001735"
     CDS             complement(9668..10555)
                     /locus_tag="ACL8JK_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS1786575.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10545..11006)
                     /gene="lspA"
                     /locus_tag="ACL8JK_001736"
     CDS             complement(10545..11006)
                     /gene="lspA"
                     /locus_tag="ACL8JK_001736"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGS1786576.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(11003..11911)
                     /locus_tag="ACL8JK_001737"
     CDS             complement(11003..11911)
                     /locus_tag="ACL8JK_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGS1786577.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11904..12101
                     /locus_tag="ACL8JK_001738"
     CDS             11904..12101
                     /locus_tag="ACL8JK_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGS1786578.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(12153..12824)
                     /locus_tag="ACL8JK_001739"
     CDS             complement(12153..12824)
                     /locus_tag="ACL8JK_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS1786579.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKFFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12878..13099)
                     /locus_tag="ACL8JK_001740"
     CDS             complement(12878..13099)
                     /locus_tag="ACL8JK_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HGS1786580.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAVRF"
     gene            13371..14180
                     /locus_tag="ACL8JK_001741"
     CDS             13371..14180
                     /locus_tag="ACL8JK_001741"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS1786581.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWSLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14361..15236)
                     /gene="aguB"
                     /locus_tag="ACL8JK_001742"
     CDS             complement(14361..15236)
                     /gene="aguB"
                     /locus_tag="ACL8JK_001742"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0050126 - N-carbamoylputrescine amidase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HGS1786582.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15246..16331)
                     /gene="aguA"
                     /locus_tag="ACL8JK_001743"
     CDS             complement(15246..16331)
                     /gene="aguA"
                     /locus_tag="ACL8JK_001743"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047632 - agmatine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HGS1786583.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALEKPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16328..17455)
                     /gene="nspC"
                     /locus_tag="ACL8JK_001744"
     CDS             complement(16328..17455)
                     /gene="nspC"
                     /locus_tag="ACL8JK_001744"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HGS1786584.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGSRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17455..18714)
                     /locus_tag="ACL8JK_001745"
     CDS             complement(17455..18714)
                     /locus_tag="ACL8JK_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HGS1786585.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTRIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDAINFNGQDIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(18711..19571)
                     /gene="speE"
                     /locus_tag="ACL8JK_001746"
     CDS             complement(18711..19571)
                     /gene="speE"
                     /locus_tag="ACL8JK_001746"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HGS1786586.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
BASE COUNT         5672 a         4540 c         3484 g         5895 t
ORIGIN      
        1 tgctggtatt atcaatcatg aactaggatt ctagttttgc aggaagtcta atgtaattct
       61 caagctgtga gttcattatg atttgtaaat ccgatatatc ttcagcagct aaaaacacat
      121 tttgaaatgt tccaagtccg ttttcaccaa aactatattc tctcttacta tacttactct
      181 tattattctc tatatagtta gagtcaaggt tcttaacctc ttgaagttca ttttctttac
      241 ttctgaggtt aaaatctttt acttctgaag ttaagttttt tgacttctgt aagtcatttt
      301 cttttacctg aaatatactc ataaagtctt taacataaat gatgttcggc ttaccaagtc
      361 caagccttac tctttcgatc agtcctattc ctttttttac atcaagctca tctaatgttt
      421 ttatggcagt tggctttgag atatttcttc ttttcataat ttcttcgaca gtaaaataga
      481 taaatactct gccttccttg tctatccagt tattcttaaa tgacattcct gtccgtttaa
      541 gaagtatgga ataaaggata attgcttctg ctgataagcc ccgaaattct tctctatcaa
      601 ctaatatctc cggtactttt aagaagttaa atctttccgc ttctctgtta taaaaatatt
      661 caaagtccat gcaagatcac ctcccttctt aaaaatttgc aaagaaaaga cgatagtttt
      721 tgcttctatc gcctttggta accattttta tgaaattttt taaagttaaa aatataattt
      781 ataatactat cttcttccat tttctgattt tagttctgaa agttccaaaa ggtgcaaccg
      841 tatttacatg aataaactta tacacttccc aagtcgctgt tttagtcgct tcatcagccc
      901 actttctcat atgcggttca aataattctt cctcactcaa cgaatcaatc attgcagaga
      961 tagaattaat attttcattt aattttgctt tcaactcttg cagagataaa tgagcgtagg
     1021 tatctgtgaa ccactgatat aaattcacca agttgattcc atttaaattt atccgatggt
     1081 gtttttactt gaagcccctt tctttcatct tcttcccatt taagaaccaa gttggtccag
     1141 ccaacctgat aagcaaggtt ttctgctgga gttctatcaa cttcatcaac tctcttatct
     1201 tttaaatttt ctggaatatt atcaaattct gaaatatatt tctcaaatgt tttctctatc
     1261 tcagctttta gttcttcttt attttcgtat gttcgcaaaa aatcaccttc tttctgattt
     1321 atcaatcctt tgatttaaaa tgaccttatt tttctattta taccttctag gaacactata
     1381 actgctgctc caaccatcgg tattccgtat gggcttaata aaaaacttaa taccaaagct
     1441 tctataccaa gtgatacatc tttatattat catcactaat taagttaaac agaaacagac
     1501 agaattatta catcctgtct ccctttattg tttttcttcc cagtcgtggt aggcagcgta
     1561 gagctgactt ttattccact ggtaaatctt agcgacttcc ttgatagctt ggtttttctt
     1621 cacaccttgc tggatgcggg tttgaatttc tacgaacaag tcttcctcgt ccttttcctc
     1681 cacaccctga ctggcaccct caacaatgag aagacattcg cccttgagtg gcgtttcagc
     1741 aatgctttct aataactcag agatagtacc tcgttggtat tcttcataga ttttggtcaa
     1801 ttccctgacc aagacaactg agcggtcacc gtagacttct aacatatttt ccaacgtgtc
     1861 tgctacacga tgaggtgatt cataaaaaat ctgtgtttca ggataatctt ttttcaagcc
     1921 aaaaaattgc ttctgctgac ctgattttct cggtaaaaaa ccgtaaaaga tatgtggctg
     1981 tggcgctaaa ccactggcaa tcaaggcaga aattcctgca gaggcacctg gaactgtcac
     2041 aactgcaatt tcttcctcaa tagctgcctt aactaaatca tgaccagggt ctgaaatgct
     2101 aggcaaaccg gcatcagaga cctgagcaat actttgccct gctttcaaga aaccaatcaa
     2161 atcaggaatt ttttccttgg cattgtgctc atgaaaactg atctgcttag tggaaatgtc
     2221 aaaatgcttg agcaaaagac ctgtattgcg cgtatcctca gcagcaatcc aatctacttc
     2281 tttcaaggtc tggatagctc gaaaggtcat atcatctaga ttgccaatcg gcgttgccac
     2341 tagatacagc ttgccatagg gagactgccc cttaaaactt ttttgaatct gcatgcctac
     2401 tccctgtata gcaactcgtc acaaaacata cattcctcgt cctgctctcg acgttgtcca
     2461 taaaaatcat tacatacgtg aaatccatca cggtaaatgc gacggacact ttcacgaaca
     2521 tgcttggcct tgacaggagc atctgcttcc acctcaccca agcgttctcg caacttacta
     2581 ttttccaagc gaagagctgt attttcctct accaggctct tgagattttt cttgatggct
     2641 tccacatcgg ctaaggttac caataattgt tgggaaaaat catccagcgc gtcaaataat
     2701 tcttttttgt ccataaaaca gccctttcct ttctttatca ttcatttttg agtttatatt
     2761 tctttcaaga ccagatattc catggcattt tgaaagctga cattagcttg ccacattttt
     2821 ctagcttcta gtaaatcttg tagaatcact cttactctta cctgcaagag gtcctgccca
     2881 cagagaactt caagaatccg taaaacctga tcctgttttt ccttatcatc tgccaagttg
     2941 gctaatttgg caacctgtag ataactttct tttttcttag ctactaacca agtcagcagg
     3001 cgttcacttt catcgaccaa ggtccaaaaa cttgcctgat tagccaactt ttctgcttca
     3061 gctcgcgatt gactaaactt agctaaaaga gtcgcttttt tcttaacaag tcccatttgt
     3121 tctaagagta agataagttt ttcttcttgc tttttaaagt ggaagatctg agtccgactt
     3181 cggattgtcg gtaacatctt ttcctcatcg ctagtcaaga agaaaatata aacttcactc
     3241 tggggttctt cgatgacctt gagcagagaa ttggctgcgt tgggatgcat tttatccgct
     3301 tgctcgatga taaagacctg ttgctggctt tcaatccctg cttgagaaaa ctgtcccacc
     3361 aattcccgaa tgcgttctgt cttgatgacc tgattgactg gcttaatcaa ggtgacatct
     3421 ggaaactctt cctgttcaat cagcttgcaa cttcggcatt tctcacatgg taagacgcca
     3481 actttatccg tacaaaagag gctcttagct aaaaattgcg ctatttccaa gcttccaaag
     3541 aaacctgaaa agagataggc gtgattgagc tggtcttgtt ctaagatacg gacaaaacgg
     3601 tcaaactgag ctggttgcca agcctttagt tgatcttgtt tcatttggcc aagcccattc
     3661 cgtcaaacaa gacagccttg gtagtttcca caacttgctc caaagggaga ctagcatcaa
     3721 tcttgacaat gcgatttccc tctttatcca gaagagaaag gtagccttga cgaacttttt
     3781 tatgcaagtc caacccttcc aaatccaaac gattaacctc gcggtcacta ttagcagcaa
     3841 tacgagccag cccttcttcc acctcgatgt caaaatagag tgtcaaatcg ggtttgaggc
     3901 catctgtcgc aaactgattg agccagtcaa tggcttcaat atctaagcca cgaccaaatc
     3961 cctgataggc aacagaacta tcgataaaac gatccatgat gaccaacttg ccagcttcaa
     4021 gtgctggaag aactttttcc accaaatgct gtctgcgact ggcaatatag agaagtagct
     4081 ctgttttagc atccatctga gtatgacttg gatccaaaat cacttcccga atcttctccc
     4141 caatcaagac tccgccaggt tcacgggtcg tcaacacctc tactcctttt tcctctaaaa
     4201 ttggtagcag agcctctaaa acactggtct tgcctgctcc ctctggtccc tcaagagaga
     4261 ctaaaaatcc ttttgacatg tctaactcat ttctttttta ctacttctat tctatcaaaa
     4321 aaataggggt ttgtgacaat atttttgtct tctcatttca tactcaatga aaatcaaaga
     4381 gcaaactagg aagctagccg caggctgtac ttgagtacgg caaggtgaag ctgacgcagt
     4441 ttgaatttga ttttcgaaga gtatcagcca ccataaaaga ggcagtcaaa gctacctctt
     4501 atttacctag ttcttgtgtt cgtttatagg cttgatgaac tgcctccatg actgtgcctc
     4561 gaaaagcatg cgcttctagg cttgctacgc cagcaatagt cgaaccgcct ggactacaaa
     4621 cttgatcttt caaaactcca ggatgttgct gactttcaag gaccaattgc ccagctccta
     4681 ccacagtttg tgctgccatt ttcaatgcta tttctcgtgg taatcctgtc tgaacacctg
     4741 catctgccaa ggcctcgata aaaagataga caaaggctgg tccacaacct gcaagacctg
     4801 tcgctgcatc gattaaactt tctcctagtt caaccaagag accagccttg gctaaaagct
     4861 gataaaagag ctcactgtcc tcagccctgc aattaggaga caaggcataa ctaatcactc
     4921 cttgcccgat agaagcaggg gtattaggca tcatacgaat aattcggtgt tgacttggga
     4981 taagacttgc tagtttttct aaggtcaatc cagctgccat cgaaatcaaa agaagacttt
     5041 ctcttttttc aaggatggtc tggtattgag aaagcagttc agaaaactga gcaggcttaa
     5101 ctcctagaaa aatcacatct gcttctgcaa acatttcttc attgctggaa gcctgaccac
     5161 caaagtctgc aatgaaagca tctaccttag cttgactacg attggcaagg agaatctcat
     5221 ctgacgtcct agtctgcaag acagattttg ccaagctagc acccatattc cccaaaccga
     5281 taaatccaat cttcatctct tactccctta tctgcccatc accggcaacc acatacttgt
     5341 agctggtcaa ctctttcaag cccatgggac cacgcgcgtg caatttctga gtagaaatcc
     5401 ccatttcaca accaagacca aattgtcctc catctgtgaa acgagttgag gcattaacat
     5461 acaccgctgc agagtccact tgatctgtaa agtatgctgc agcttcagca ttttccgtca
     5521 caatagcatc cgaatgatgg gtgctgtggg attcaatgtg cgcaaccgct tcttctaaac
     5581 tgctcacaac cttaacagca aggacatagt ctaaaaactc ggtgtcaaag tcttgggtct
     5641 cagctgcttg acctgaaaca aactggcttg ctttgctatc caagcggaat tgaattggtt
     5701 ccagtccggc ttccttacgc tctgcaacca gcatttgatc caagcgagga aggatgcttg
     5761 ctgccttgtt ttcatgaacc agcagaacct ccatggcatt acaaacagaa ggacgactgg
     5821 ttttagcatt gttgatgata gacagcgcct tgtcttcgtc tgcatcctta tccacataga
     5881 catggacaat cccagtccct gtctcgataa caggtacaat cgcattctca accactgcat
     5941 tgatcaagcc agctcctcca cgaggaatga gaaggtctag atagcccttg gccttcatca
     6001 tagcataact actttcacgg ctagtatcct ccaccagttg aatcacattt ggatgaatag
     6061 tagtcgtctc caagcccttc ttcaaggctg tgacaatggc atgggttgtt tgataggcat
     6121 ccttaccact acgaagaaca accgcatttc cactcttaag agtcaaagca gccgcatcag
     6181 acgtcacatt tggacggctt tcatagataa taccgatgac acccatagct acacgttttt
     6241 ttgtgataac caaaccattt tcaagctgac ttgtttctaa aacttcaccg attggatctg
     6301 gtaaggcaac cacttcacga attcctcttg ccatcgcttc tatacgatct gcatccaaat
     6361 aaagacgatc caacatcaca tctgagattt tccccttagc cgctgccata tcgagggcat
     6421 tagccgctaa aatttcctca gtagcagcca ctaagtgatc agccatggct agcaaggctt
     6481 ggtttttcac ttcttcacta gctgtgttaa tcgatttttt aacagcctgt acctgttcaa
     6541 attgttcttg tctactcacc atagtttacc tctaaaattc tgtaaaaagt agttggattt
     6601 caggagtaat ggaaatccag tcgtcacggt aaatcaagac acccttggct ttttgagaac
     6661 gcaacatatc ctccaaagca gatgctccaa attgcacgcg tccttttcca agtgattttc
     6721 cactttcctt gtcaaatact gtcacgatat caccgtaaga aaaggctcct tctgcttcaa
     6781 cgataccaga taagagaaga ctctttccat gttgagagag agcttccgca gcccctttat
     6841 caacccaaat agaaccttga ctctgagcat agaaggcaag ccattgtttc tgggtacgaa
     6901 gccccttctc ttgagcaaca aagtaagaac catcctcggt ctcctctgcc gcctcaatca
     6961 tggaatctga tttcaaggat gagcagatat aaacaggaac tcctgattcc gtcgcgatag
     7021 ttgcagcctt gattttggtt aacatacccc cagttccgtt tgacgaacca gctccaccag
     7081 ccatatcaat aatctcacga ttgatggtct cgattctctc caagcgtttg gctcttggat
     7141 ctgaattagg atttccagta tagagaccgt ccacatctgt caagaaaact aaaaggtctg
     7201 cttggaccat cgccgctact tgagcactta gagtgtcatt gtccccaacc ttgagctcat
     7261 caataacgac actatcattc tcattgatga taggaattgc cccacggttg agcaaaaccg
     7321 acaaagcctg atgggcattt ttataacgac gcttatccac aaagtcatct tgggtcagca
     7381 agatttgtgc agaaacgatt tgacgcaaga gaagattggt cgtatattct tccaacaaaa
     7441 gtccctgccc taccgctgct gaagcctgtt tatcagcaat tttagtcgga cgctttttaa
     7501 atcctaaggc tccaaaacca gccgcaatgg cacctgaaga caccaaaatc aactcatgac
     7561 cagcctcgtg cagcatagcc aactgctggg taatatcctt taccttacta cgtgataaac
     7621 ttccatcctc atttgtcaga gaagaagtac ccaccttaaa gacaatccgt ttgtatttca
     7681 tagtctcact ccgattattc atatttatcc attataacat gaataacagg aaatagaaaa
     7741 gagttgatag gaaaaagaag gccctaaaac cttcttttct actactgttc tgattccgat
     7801 ttgtttacac tcgtttcaga gctttgtgaa gttgaggatg tcaaatcttg actagttgaa
     7861 aaatttgtaa cactttcatg ttgactcgtt tctttatttt caagatcctt tttcactact
     7921 tctttggatt cttttatttc tgaatgactt gtagttttaa ttgtagcaga tttctcgatc
     7981 gaaacatcca ctaaccaggc accacttgaa tccacagtat aaccttctgg tgtcttaccg
     8041 ttcacaagta attgaccatt ttctttcaag aagtaccatt tatccttgtc cttgatccaa
     8101 cccacagctc gtgaaccgtc tgtcttgtag aaataccaat catttgcctt tttatgccag
     8161 ccttgcttca tagctcctga atcttccaga taataatgtt gaccagcaac ttctatctca
     8221 cctgtcttca tgacaccagt agaatccata tagtaccagg tttctttatc ttttacccag
     8281 cccattttca tttcccctga tggagcaaag taataccatt gccccatata ttgaagccat
     8341 cctgtcttca tagaaccatc aacatccaaa taataccact gctctttatc ttgaacccaa
     8401 ccaatttcca tctgattttc tttgttaaaa taataccaga ttccagcgat tttcttccaa
     8461 tttttagcag aagcaccaga gtctgtcaaa tagaaccaat gattgttcca ttttttccat
     8521 tgattctgta acaagatacc cgtttggtta aagtaatacc attcaccttc gatttcattc
     8581 caaccgacag catactctcc tgtagaatca ggcgcttgat accaccagtt cccatatgca
     8641 ctcttatgcc aaccagcttg aaaacttgga atcggcttgt aggatgttga aatattgaca
     8701 aaaccgtctt ttcgaatatc aaaaactgtt gcatcatagt ctttgctggc tgcgttgatt
     8761 ctctcaattc ctcgttcttt gagccaatta acatactcac tatcaacacc atttttccaa
     8821 ggtagactat ccgaagtttg aacaatcaaa ctcggactca aatttttaat gaaatccttg
     8881 gtatttgatt tgttggtatc atggtgatga ttaaacttca tcaaatcaac ttttccaatg
     8941 agaggaccat acttgtcttc tgctccatga acattatcta aatcgccccc aaggtaaatt
     9001 ttcttgccat tgactttcac cacgctaatc aaggaattgg aattgtcatc ccaaattttc
     9061 tttaattcac ccgatgaatc agtttcattt tcataattat agagctgaat atccatgtcc
     9121 ccaaactgaa aatgagcatc cccttgtgtg atattttgaa taactgaaac acctttttct
     9181 gcagcagtct gtaaaacctt atcatagcca tacagattat cccatagacg ttcagaatta
     9241 gtaatacgac tatcactata tttcttaaga tagactcggt caactggata ggtagacagt
     9301 aattcatcaa catttccaat atgatcactg tgggtatggg tcaccaaaat aaaatcaagt
     9361 ttttggacac ccaattcctt caaacgacga aagacacggt ctgttagaac atgcttataa
     9421 gacgtttcaa ttccttctct ccatggataa cgagaatcac ttccatctgg gaaatcataa
     9481 tcttctcctg tatccaccat ggcaaaatgt ccattgcttt caagaataat cgcatcactg
     9541 ccaccttctt gaacattgat aaagtggatt ttatttcctg aactttcttg agcctgaaca
     9601 ttcccatacc atgacaaacc taaaaaagcg cctacaagtg ctaaactagt taatttcttt
     9661 ttcattctta ctttctcaat ctctccaagg tttccttaaa aatctctggg atatctgctt
     9721 taaattccaa ggtcttacct gttctcggat gagtaaaacc taaagtcttg gcatgaagaa
     9781 attgtccatg tcctttcaaa gtcttgcgag gaccatagac ctcatcacca gcgactggat
     9841 ggccgatata agccatgtgg acacggattt gatgagtgcg ccctgtctcc agttgcaact
     9901 ctactaagct ataatcgcca aagcgttcca agacgtgaaa acgcgtcact gcaggcttcc
     9961 ctttagcagt tacagcctgt ttcttacggt ctttttcact ccggccaatc ggcgcttcaa
    10021 ttacaccacg atcattaggc agatttccat gaacaatcgc ccaatatttg cggagagact
    10081 ttttatcttt gagttcttgg gcaagtacta gatgcgcatc atcgttttta gcaatcatga
    10141 gaagacctga cgtatcctta tcaatacggt gaacaatccc tggacgcaga accccattga
    10201 tacccgacaa gtccttaata tgatacatga gggcatttac tagggttcca ctggtatgac
    10261 cagcactcgg gtgcacaacc attccctgag gtttgttaac gacagccaca tcctcatctt
    10321 ggtagactat ttctagcgga agatcctcag ccacatactc taatacctct ggttctggca
    10381 catggtaagt gacgacatca ccctcttgga ctgtgtattt agctttcttg acttgaccat
    10441 tgaccaagac ctggcctgat ttaatttgtt cattcgcgag actacgtgat aattctgaca
    10501 aatctgacaa agccttatcc aaacgcagac caccagtttc aattttaatt tccatttatt
    10561 tcctctttta gcattgcaat caataaaata atcactccaa ccgtcagata gctatctgcc
    10621 acattgaaaa ttgcaaagtt gataaagtca aggtggaaca tatccacaac aaagccctga
    10681 ctgaccctgt caataaagtt tccaagacca cccgcgatta ttagagtcaa acccaagacc
    10741 atccagaatg agtcctccat gtgtttatgt aaataccaaa tggcacctat cacgacaacc
    10801 agagtaatga cagcgaataa cagctgctga tcttgtaaga tagaaaaggc tgcacctcga
    10861 ttttgcaggt aggtcaagct aacgaaattg ggaatccagg agcgcacttc acccagtgga
    10921 atctgctgga cgatatagga tttgaccaac tgatccagcc caattaaaag cagtacaatg
    10981 actgccacta ttgctctttt tttcatgatt tcctcttttg atcaaaatat tcttgcatga
    11041 cttctacgaa gagagtccca gcttgactaa gctccacttc ttcacgttta acatagacca
    11101 tgcggttatc taggttatcc ttgagacgaa taactgtaat gccattaaca ctgtcactat
    11161 ctaaaaatcc agaacctgtc gcataggcgt ccgtccgctc caaaatacca ttcaaggtgg
    11221 cacggtctgt cacattaaac atctgtgagc tagcgctggt atcgacaaag ttctctgaat
    11281 aataaaggta ctcgtctttc tcttgagtga aacgaaccgt tggtaaatcc gctaaatcct
    11341 ccatgactaa ttcctctttc tgggctaaag gatgaccctc acagagataa atatgggtat
    11401 ggaaaggaat caattcgatg acctccagac ctaacttttc aacccgttgc ataatcccct
    11461 ttttattttg attgttgagg tagataatcc caatctcact atgcccttgc gccacttcat
    11521 ctaatatttg aacagtagtt gattcaaaaa tacggaagtt cttatagtca ggatagcgct
    11581 ctgaaaaggc cgtaatagtt ggtggtaaga agtcatagtg ctggctagca acggaaaatt
    11641 catctttttc ttcttcagga ttggcatact gattttgaaa aatatcaaat cctttaacca
    11701 attcttgcgc tttttcataa aattccatcc cacgacgggt caagaaagtc cctgagctgg
    11761 tccgacggaa aatcttaaag cccaactctt tttccaaatc acgaacagaa atagacagac
    11821 tcggctgact aacatacatc ttttcagcag cttcacgaaa agtaccacta ttggcaatag
    11881 ccacaacata gcgtaattgt tgaatgttca tcttctaccc ccaacttctt tatcttttca
    11941 ttataccata ttttagaagt tttccaaaaa ggaaaaaaga acatcctatt cttcttaact
    12001 atcttcacta tctgcctttc tcacgccaat cttattttca aaatcaattc aaaaaaataa
    12061 gtggctacac accacttcag tatcggaaag aaaaacgttg actatttgtg aaaaaagaaa
    12121 attccggaaa gttccgacat tattttagta agctaacttc ctgaaaatag gagcaaccac
    12181 acatcccaga aggcagtgat attaatgaga atatgaacta gtattggata gtagagattt
    12241 ttagtcatgc gatacaatag agctaaaata agacctccac tagcataaat gaaaaaagca
    12301 agaggagtta aagcaaaatt gatatgaata taaccgaaaa taatagcaga aagcaaaaca
    12361 tctccgtacc aaggcgagtt tttgaaaaag gttgtcataa gcacaccgcg ataaatcaat
    12421 tcctcagcaa taggggcgat gaagcaaacg atgagcaaga aataagggaa ctcctgtctc
    12481 cccatcattt ctaccgtttc attcaaagaa atctgatttg aagacaggga tatgaaatac
    12541 gaaaagagga agtcagacat atatgaaatg atgtagccca gtaaaaggta gatgaagtac
    12601 ctcagctgcc acttgaaatg aaaaaatttt tttcctgcaa aaaccagtag atagatgacc
    12661 gctaagaaaa gaactccgct ctccatcaaa agcagaatct gaaaaaattc acgacttgct
    12721 ggtagatagg gctttgcgag gtgattgaaa actctccaaa accaagttga tttgtaaaaa
    12781 attaaggaca atgctagtaa aatttgaata gcccgttttt tcatattaaa ttctctgctt
    12841 tctccacttg tttcttcata ttactaataa attttactta aaatctcaca gcacttcctt
    12901 tgcaaagatg attgcctcct ccaatatatc ctaaatcata ggtgcctctg ggacaaaatc
    12961 catgaaccgg cagagttaat actggttcta tttcccaatc gtacctacca ttaggatttt
    13021 taccatatga atctgctcca ccttgtatca gctctaattc ttcatttgtt agatttatat
    13081 tttttgtcat taaaatcatg atatatttcc tccattattc ttcagattag ttgagtaatc
    13141 tgatactcat acctacttac aaaaaaacta ttatattaag ttggtttttt aatttgtcta
    13201 gttgcaacat tgacaaacat agtatagcat atctttgcca aatatcctct tcaaatcatg
    13261 aattgtcatc aaaacatctt aaactataaa atcaattagt ctcaagcttt ctatcaattt
    13321 cttctccaaa atatgctata atactaccaa aagataaaga aggaagacct atgattaaac
    13381 tactagcctt ggatatggat ggaaccctcc tcaatgaagc caaggaaatc ccacaggctc
    13441 acatcgctgc tattcaccaa gccattgaaa aaggtgtcaa actggttctc tgtacgggtc
    13501 gccccctttt cggtgtcctc ccctactaca aaaaactggg gcttgacctc cagaacgaat
    13561 atgttattgt taacaacggt tgttcaactc accagaccag tgattggagt ctagttgact
    13621 ggcaagaact gagtccagct gacatcgaat acctctatga ccttgctgaa aagagtgatg
    13681 ttcagttgac actttttgac gagtcacatt attttgttct cggtggaaag cccaatcaag
    13741 ttattgaaaa tgatgctaaa ctagtatttt cagacctgac tgaaatttct cttgaagaag
    13801 cgactagtgg aaagttccgg atgttccaag gtatgttttt aggaacaaaa gaacaaacag
    13861 acgattttga gcagcgtttt gctgaagagc tttgccaacg attcagtgga gttcgttcgc
    13921 agcctgtcat ttatgaagca atgccgcttg gaacgacaaa ggctactgct ctttcacgac
    13981 tagctgagat tttgaagatt gattcctcag agattatggc catgggcgat gctaataacg
    14041 atatcgaaat gctccagttt gcagggcttg ggattgcaat gggaaatgcc agcgattatg
    14101 tcaaatctct tgcggatgcc gttacctcaa gcaacgaaga agacggcgtt gcgcgtgcta
    14161 ttgagaaata tattctataa aaaagaaaag caaatagaca gaagttactg ctatttgctt
    14221 ttttgctaat attttaaaat acggactaat caatagacaa gaatagcgaa tcataaaaat
    14281 cgatttacta gatgccatag tatcttatag ttgctaataa gaagttagtc tagcagaatg
    14341 aatctctcat ttctcccaca ctaatctgta atttgtctat acatttctgg tcttctatct
    14401 cgaaacaagc cccagtttag gcgttcactt gctcccttgt ctaggtcata agtagctaac
    14461 agaacagctt cttcttgtct ttcagctcgt tctagaatag ctcctgtttc atccgtcata
    14521 aaggaggaac cgtagaagtc aagactggaa ctctgtccgc cattttcctc actaggagta
    14581 acctcctcta aaccataacg attggctgcg atgactggaa caatattcgc tgctgcgtgc
    14641 ccttgcatag tacgttgcca gtgaccacaa ctatctgtat ccaaaattgg ctctgaaccg
    14701 atagctgtag gataaaagag caattcagca ccattcaatg caagacagcg cgctgtttca
    14761 gggaaccatt gatcccaaca gataccgata ccaatcttag catagcgagt attccagacc
    14821 ttgaaaccag tgttaccagg cgtgaaatag aatttttctt gataataatg gtcatctggt
    14881 atgtgggtct ttcgataaac gcccagcact tccccatctg catcaatgac ggcaatagag
    14941 ttatacaaga cattaccatc tttttcatag aaactgattg gtaaaacaac ttgtagttcc
    15001 ttagcaatca ccttaaaatg ctgaatggca gtattttccg ctacagattg ggcatactgg
    15061 tagtagtcat actgacgttc ctgacagaaa tagggatgtt caaacaactc gggcaagaga
    15121 ataatttggg ctccttgctc agcagcctga cgtactaaac gctctgcggt ttggatattt
    15181 gttgccacat ccttagcgca ttgcatctga atggttgcaa ctcttacatt tctcatcttt
    15241 ttctcctatt ctggaatttg ttgggtgata cagtggatat tgccaccacc taagagaata
    15301 tctctggctg gtattccgac aactttacgg tctgggaaac acttgctgag gatatctaag
    15361 gccacttggt cgtttacatc ctcaaactgt ggaaccaaga cagccttgtt ggcgatataa
    15421 aagtttacgt aggaagctgc tagtcgttca cctgcgtatc gctcttcttc tccttcttca
    15481 tagatgtagc ctggcaaatc ttcttctgtc acaacttgtc gaactgcagg gataggcaat
    15541 ttatgaatgg tgaagtgaca accttttgca tctgtttcct gttctaagag ttcgagatct
    15601 gcttttgaca tggcatactg gggatcattt tcgtcatctg tccaagccaa aacaagctca
    15661 gcaggaccaa caaaggcagc aacattatcg acgtgttcat tggtttcatc ctgataaata
    15721 ccataaggaa gccaaataac tttttcagca ccaagacttt ctaataatgt gttttcaatc
    15781 tcctctttag tcaggttagg attgcgacca ggactaagca agcaactttc agttacgaga
    15841 atagttcctt gaccatcgct atggattgcg cctccttcca gtacaaaagg tttagcatca
    15901 tagacaggct tttccaaggc ctcagcaaaa cgactggcta cttggtcatc ctcttcataa
    15961 tcttgataaa gaccatcata ggtgcctccc caagcattga aggcccaatc cacggctaat
    16021 ttcttacctt tatcattgac gagaatggtt gggccagtat cacgcgccca ggcatcattg
    16081 gtgggaatgt ctaaataaac aaccttgtct ccaagatagg attgggcttc agatagatag
    16141 gcctgctcca ccaaaagata gactctttcc ccttctgcta tggtctcgat gatctgagta
    16201 aatgctcttt tagcagcctt tccttgaaaa ggccatgatc ctggtcgagt cggccatatc
    16261 atgagggtac catgatgggg ttcgtactct gctggcatgt gatagcctaa tttttttgga
    16321 ctgtccatca tgataatctc cctttaaagt cttgatagcc aaaagctttg agtaagctac
    16381 agtctccctg ttcgtccatg agatagagac ttggcaatcc aataccatta aaggtattat
    16441 ttttgacaaa agaataaatg gccatgtctt gaaaataaag tctgtctccg atttggactg
    16501 gattttcaaa actataatca ccaatcacat cgccagtcag acaggtatta gaagaaagtc
    16561 tgtaggtatg ggctttttcc tgtgactcaa agccatttct caaaggtgga cgatagggca
    16621 tctcaagtac atcaggcata tggcaggtcg cagaggcgtc taaaaccaag atttccatac
    16681 cgttttctac aatatctaat acctcagttg ctaaataacc cgcattaagc gcaatggctt
    16741 caccaggctc gatatagatt tcaagattgt aagtttttcg gatacgcttg atttctgaaa
    16801 tcagcaaatc cacatcgtaa ccttctcttg taatatgatg accaccaccc atattgagcc
    16861 attttacctc atgtaagtag ggaccaaact gttcttctac tgctttcaaa gttgtttgta
    16921 aatcatctgc tccctgctcg caaagggtat gaaaatgaag tccgtcaacc aaatctagca
    16981 aatcactcgg aatcttgtct atagtaactc caaagcgaga accaggtgca caagggtcat
    17041 agagcgcgtg atctccttga gttgaacact gagggttgag gcgcaaacca acactgacac
    17101 cagcctctcg acaacgcgaa ccatgcttac gcaactgtct ctctgagtta aagacgatat
    17161 ggtctgttat cccaagcaat tcctccatgt cctcatcctt gaaagctggt gcaaaaacat
    17221 ggacttcacc aggaaattct tcccttgcca atttggcctc atagagtcca ctagctgtcg
    17281 tacctgatag atactggcta atcaagggat aagttttgta gagggaatat gccttctggg
    17341 caagcaagac cttgcaaccg gcctcttctt gtacatattg tagaatgcgg caattagctt
    17401 ctaacttggc caagtcaata acataggctg gtgttggtac ttgttctaac ttcattagtc
    17461 caccatttgt ggattttcaa ccacaaccca tggcaaacca tactcattca aagcttccat
    17521 gaatggatct ggatctaact cctcaaggtt atacactcca gcttgtttcc aagtaccgtt
    17581 cataactaat tttgtcccaa tcatggctgg aacgcctgtt gtgtaagaaa tagcttgtga
    17641 accaacttct gcgtaacatt cctgatggtc gcaaacattg tagatataga tggtcttttc
    17701 aacaccgtcc ttgacacctg taaagataca accgatattg gttttaccaa cagtgcgcgg
    17761 gccaaggctt gcagggtctg gaagcaaggc ttttaagaat tgaatcggaa caatgtcttg
    17821 accgttgaag ttaatagcat ctgtacgaag gagtccaaca ttttcaagac atttcatgtg
    17881 cgtcaagtaa gattgaccaa aggtcataaa gaaacgaata cgtttaacac ctggaatgtt
    17941 cttagccaat gattcgattt cttcgtggtg aaggagatac atgtcttttt gtccaacttg
    18001 agggaaatcg tactcgcgct tgatagacat ggcttcaacc tcgacccatt ttccatcttc
    18061 ccagtaagaa cctggcgcag aaacctcgcg tagattgatt tctgggttaa agtttgtcgc
    18121 aaatggataa ccgtggtcac caccattaca gtctaaaatg tcgatatagt ggatttcatc
    18181 aaaatagtgt ttgagggcat aagccgagaa aacactagtc acacctgggt caaaaccaga
    18241 accaagcaga gcggtcaagc cagcttcttt gaatttctcc tgataagccc attgccatga
    18301 gtagtcaaag taggctgtaa aaccaagttc cttgcaacgt ttttcataaa tagcacgcca
    18361 ctcagggtct tctgtatcct cagcctcgta gttggctgta tcgatatagt gaacacctgt
    18421 tgccaagcaa gcatccatga tggtcaagtc ttgataaggc aaagctacgt tcaacacagc
    18481 ttctggtttg tagctttcaa tcagggcaat cacttcttca accttatcag catcaagagc
    18541 tgctgtctca atccttgtac ttgttttgcc ttccagttta gctttcaagt catcacattt
    18601 tgacttagta cggctagcaa tcataatctc tgtaaaggtt tcgctatctt gacaaatctt
    18661 tgaaatagca acttgggcaa cgcccccaca tccaataact agtaaacgac tcattttttt
    18721 ccttcctctt cttctaaaat gtcctcaaca tacttgggca acataaaggc tcccacgtgt
    18781 aagtttgcag tgtagtattc tgtgaaaagc tgacgttttt tccagccttc cttgtcaaaa
    18841 tctttgacag ggtggtattt ttttgatgca aatccaaaca accaatagcc agctggactg
    18901 gttgggatat gggcctgata gacccgactg attggaaagg cttgattaac cttgcgatgc
    18961 atgcttcggc aagctgactc atcctcatca aagaagggac tcccatgctg ataaatcatg
    19021 ataccatctt cctttagagc tcgataacta ttaccgtaaa attccttggt aaagagccct
    19081 tccgtatggc caaatggatc tgtcgcatcg ttgatgataa tatcgtagtc atcttcgcag
    19141 tttcgcaaaa agcgtagccc attttgataa taaatggtaa cacgaggatc atctagccct
    19201 gcggcaaaat ctgggaaata ctcacgacag acttcaacca acatctcatc tggttccaca
    19261 atgtcgattt gttccagctc aggatagagt gttaatactt gggcaacacc gccgtcacca
    19321 cctccaataa ccaatacttt ctttggattt gggtggacag ccatgggaac gtggacggtc
    19381 atttcattgt agacaaaatc atccgcatct gaaaacaaaa catgcccatt taaaatcagt
    19441 attttcccaa aagctggcgt atccaagact tcgatatcct gccattcact ttttccagcg
    19501 taaagttgct tggctgttct cagagacaat ttgacatctg gagtatgaac ttcagaaaac
    19561 cataaatcca tctatttctc cttatattat a
//
LOCUS       DBERXF010000044        18578 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.44, whole genome shotgun sequence.
ACCESSION   DBERXF010000044 DBERXF010000000
VERSION     DBERXF010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18578
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.44"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(39..2492)
                     /gene="phtA"
                     /locus_tag="ACL8JK_001747"
     CDS             complement(39..2492)
                     /gene="phtA"
                     /locus_tag="ACL8JK_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HGS1786587.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLAPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVTLARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNEDVDSLLKQLYALPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYH
                     FIPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQQTPEPSPGPQPAPNLKIDS
                     NSSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKK
                     ENVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDD
                     LLAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAY
                     VTPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRV
                     KGEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDL
                     FATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEV
                     PQVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEK
                     LLALLKGSNPSSVSKEKIN"
     gene            complement(2746..4479)
                     /gene="ptsP"
                     /locus_tag="ACL8JK_001748"
     CDS             complement(2746..4479)
                     /gene="ptsP"
                     /locus_tag="ACL8JK_001748"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGS1786588.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKEAGEAYAKQKAEWALLKDAKTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVAYNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(4485..4748)
                     /locus_tag="ACL8JK_001749"
     CDS             complement(4485..4748)
                     /locus_tag="ACL8JK_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGS1786589.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            5099..5317
                     /gene="nrdH"
                     /locus_tag="ACL8JK_001750"
     CDS             5099..5317
                     /gene="nrdH"
                     /locus_tag="ACL8JK_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGS1786590.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            5398..7557
                     /gene="nrdE"
                     /locus_tag="ACL8JK_001751"
     CDS             5398..7557
                     /gene="nrdE"
                     /locus_tag="ACL8JK_001751"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGS1786591.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            7745..8707
                     /gene="nrdF"
                     /locus_tag="ACL8JK_001752"
     CDS             7745..8707
                     /gene="nrdF"
                     /locus_tag="ACL8JK_001752"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGS1786592.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            8889..9650
                     /locus_tag="ACL8JK_001753"
     CDS             8889..9650
                     /locus_tag="ACL8JK_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS1786593.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9761..9970)
                     /locus_tag="ACL8JK_001754"
     CDS             complement(9761..9970)
                     /locus_tag="ACL8JK_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HGS1786594.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDDLEEFKNLFLNFINPEE"
     gene            complement(10013..11419)
                     /gene="lacG"
                     /locus_tag="ACL8JK_001755"
     CDS             complement(10013..11419)
                     /gene="lacG"
                     /locus_tag="ACL8JK_001755"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGS1786595.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDHENPADVRAAELEDIIHNKFILDATYLGHYSEKTLAGVEAILAANGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            complement(11634..13325)
                     /locus_tag="ACL8JK_001756"
     CDS             complement(11634..13325)
                     /locus_tag="ACL8JK_001756"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HGS1786596.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARYFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FNLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            complement(13325..13642)
                     /locus_tag="ACL8JK_001757"
     CDS             complement(13325..13642)
                     /locus_tag="ACL8JK_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS1786597.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVQ"
     gene            complement(13678..14514)
                     /locus_tag="ACL8JK_001758"
     CDS             complement(13678..14514)
                     /locus_tag="ACL8JK_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGS1786598.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            complement(14748..15728)
                     /gene="lacD"
                     /locus_tag="ACL8JK_001759"
     CDS             complement(14748..15728)
                     /gene="lacD"
                     /locus_tag="ACL8JK_001759"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGS1786599.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            complement(15730..16659)
                     /locus_tag="ACL8JK_001760"
     CDS             complement(15730..16659)
                     /locus_tag="ACL8JK_001760"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HGS1786600.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            complement(16670..17185)
                     /gene="lacB"
                     /locus_tag="ACL8JK_001761"
     CDS             complement(16670..17185)
                     /gene="lacB"
                     /locus_tag="ACL8JK_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HGS1786601.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGDYHD"
     gene            complement(17216..17641)
                     /gene="lacA"
                     /locus_tag="ACL8JK_001762"
     CDS             complement(17216..17641)
                     /gene="lacA"
                     /locus_tag="ACL8JK_001762"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HGS1786602.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            complement(17798..18295)
                     /locus_tag="ACL8JK_001763"
                     /pseudo
     CDS             complement(17798..18295)
                     /locus_tag="ACL8JK_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
     gene            complement(18311..>18578)
                     /locus_tag="ACL8JK_001764"
     CDS             complement(18311..>18578)
                     /locus_tag="ACL8JK_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGS1786603.1"
                     /translation="QAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKACNHAL
                     SKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIIGF"
BASE COUNT         5491 a         3855 c         3377 g         5855 t
ORIGIN      
        1 aaaaatgaaa gcctctttat cgagactttc atttttcatt agtttatttt ttccttactt
       61 acagatgaag gattacttcc ttttaacaac gcaagtaatt tttctgcttc tgccatgata
      121 ctattgttat ccataatttg aagagtcaaa ttatttcgta aaccagctag agtttctgtt
      181 gcattggctt tcagactaga atccgttact ttcgcaagca aaacttctgc ttctttgagt
      241 tgggcttcta ctttttcagt ctctacttga gggacttctg gctcagcagg tgtttcctct
      301 actggctctt catccgcttt gaagttctta tttggatctt cactgtggtc tttcttgcct
      361 aacacatgct cactggcatt gccccatcca tcattagaat gtggacgttc gtcagggtgt
      421 tctacgtagt acttaatcgt cgcaaacaaa tcttccaagg tatagccatt tggagctttg
      481 tatgtgtgat catcaaacca agcaaattta atgttatggt aatgatcctt atgaggaata
      541 atcaaattac cgtttttaac ctcaactgta tgctcaacca tatatggaag tcgaacgagt
      601 ggaattcgtt tttccccttt cacacgattg taaatagctg ctgcactatc tccagttgga
      661 tttgctttaa catctgcgtc tggagatgga ggtaggatac ctttttcttt agtataggct
      721 tgagctgcaa ctttttcctt atcagaaagg ctgtcttttc caatccagtg actatggccc
      781 atatgaggcg ttacatatgc atctccttca tcactgatta tatcatgttc atcaaaaatg
      841 taaccatctg acgttgtata cttatcagct aattgagcaa tacgaacttc gtcttcagta
      901 tactcaattt gagaatttgg cttgccaagt cgctctggat gggtaattgg tgctaggaat
      961 gccaataaat catctaccaa tttttcttta ttagtcgatt catcattcaa gcgttctaat
     1021 aatttgtcta aggcttggaa atcagaatta cgacccttat tttcaaacaa ggctttatga
     1081 gcctcagtta acagattata tgctttatca taaaattctt ggtcacgagg agcaacattt
     1141 tcttttttag cagttaaagt gtgtgaaaca ctctcttgtt ttgataactt gctttcaaga
     1201 tttttaacag tttcagatgg taaatctttc gcaaaaacat aacgagagat gcccttttct
     1261 tcgaatacat atccttcccc aacttttcgt accagctgac taaccaaaga agaatttgag
     1321 tctattttaa gatttggtgc aggttgcggg cctggactag gttccggagt ctgttgtgga
     1381 cttggttgtt ctggccttga atccggtacc caatggtttg aacgataacg aaggggaata
     1441 atacgagcga ttcgttcttc caattcagac atttgagagt aagggatgaa gtggtaatga
     1501 tctccgtgtg gcactgcaac acctctagct gttcgacttg tgatttgtgc tggatcaaag
     1561 acaaggccat cagattctac gtgtcgttgg ctgagtggca aggcataaag ttgtttcaga
     1621 aggctatcaa catcctcatt actttgactt gcttgactgt tagtgttgct gttgttactt
     1681 gtgttagtat ttgtagttcc tggattgctt acagaaggta cccagtttgt tcttgaagtg
     1741 ttatcgctat tttgtcggcg ataggttctt gaatttgaca gatttccccg accagatagg
     1801 aaggcttctg cagcagctaa ctcgctagct gataactcat tcttaggaat gtaatggtaa
     1861 tgatctccat gaggaacgat ataagcatca ccagtatcct ctatgatatc agaagcatta
     1921 aagatataac catcatctgt agtatagcgt ccttgcgaac gtgccaaggt aacagcacca
     1981 tcgtttcttg gagtcccacc ttcacgatgt tgactatgtt cttgtttttg tcgattgatt
     2041 tcctcttttg tacggacatt atccgcgtgg gcagcatcct taaggtaaac atagtatttt
     2101 ccatctacct tgataacata tccacccttg acctcattaa caatatcctc atcttttagc
     2161 ttatagtttg gatctttcat gagtaattct tcactgaaaa tcgcatcata aggaacctta
     2221 ccattgtaat aatgatagtg gtcgccatgt gaagtgacat agccttggtc tgttatcttg
     2281 atgacgattt gctcagcatt gattccttca cgcttgctaa cctcatcagg agccaaattc
     2341 tccgtttttt gcgtcgcttg ttttccatct atataggaaa cacgattatt ttccttaacc
     2401 gttctagctt gatacagtcc caactcgtaa gaacaaacac ttaaaatcaa agctgccgca
     2461 gaaccaacaa ggtatttctt attaattttc atcgaaactc tctttctatt tgatatttct
     2521 agttgcaatt catttctaaa ttgcagaaac tcccctctat tacttaactg gttaatagtt
     2581 tactcctaaa tctccaactt gtcaagaatt ttatgaacca tttaagtatt ttttgttctg
     2641 accactactt tttcaaggtt ggactttcta taagaaagat tttcttgaaa attcttttta
     2701 aaatatcaaa aaaatccctg taactgagtt gcagggactt ttcgattaat caaaattaac
     2761 gtattctttt tgaagttcaa gaacttcttc cattgttgag cattctgtaa gggcacggtt
     2821 tgcgtactct tccatcttag ctgtgtcgag tttcttcatc aagctgcgtg tacgaagtac
     2881 agatgttgct gacatagaga actcatccaa gcccattccg acaagaagtg gaacagcttg
     2941 ttggtcacca gccatctcac cacacatacc agcccattta ccttcagcgt gagctgcttt
     3001 gatcacattg ttaatcaagc gtaggattga tgggttgtat ggttggtaaa ggtatgaaac
     3061 ttgttcgttc atacggtctg ctgccattgt atattggatc aagtcatttg taccaattga
     3121 gaagaagtca acttctttag caaattggtc tgcaagcata gccgctgcag gaatctcgat
     3181 catgatacca acttgaatgt tatacgcaac tgcaacacct tcagcaagaa ggtttgcttt
     3241 ttcttcatca aagactgctt tcgctgcacg gaattctttc aagagcgcaa ccattgggaa
     3301 catgatacgc aattgaccgt gaacagacgc acgaagaaga gcacggattt gtgtgcggaa
     3361 catagcatct ccagtctcag agatagagat acgaagagca cggaatccaa ggaatgggtt
     3421 catttcgtga ggcatatcga agtaaggaag ttccttatct ccaccgatat ccattgtacg
     3481 aacgacaaca ggtttaccgt tcattccttc aagaacagcc ttgtatgctt catactgctc
     3541 atcttcagtt gggaagtctt gagaatccat gtacaagaac tctgtacggt aaagtccaac
     3601 agcttctgca ccgttgttgt taacaccttc aacgtctttt ggagtaccga tattagcagc
     3661 caactcgaag tgtttaccgt cagcagtcac tgttttagcg tctttcaaga gcgcccattc
     3721 agctttttgt tttgcatagg cttcaccagc ttctttaaat tctgccgctt gttcatcagt
     3781 tgggttgata ataacctcac cagtgatccc gttaacagca aggatgtcac cgtctttaac
     3841 gatttcagtg atgttatttg tacctaatac agcagcaatt tcaagtgtac gtgccatgat
     3901 agctgagtgg cttgtacgtc caccgatgtt ggttacaaaa gcttttacaa agtttttgtc
     3961 caattgagct gtatctgaag gagtcaagtc atgcgcaatc acaatcactt cttcattgat
     4021 agaagctggg tttggcaatt ttttaccaag aaggtttgcc aatacacgtt ttgtcacgtc
     4081 gcggatatcc gctgcgcgtt cttgcatgta tgggttgtct tccatgcctt caaagatagt
     4141 gataaacata tctgtaactt ctttcagacc tgcttctgca ttcactttct tcgcacggat
     4201 agtttccttg atttggctga tcatttctgg gtcagcaaga accattaagt gagcatcaaa
     4261 aacttgagct gcttcttcac cgagcgtacc tactgctttc tcgcgaataa cagaaagctc
     4321 gtcttgtgat gcctgtagag cggcatcaag gcgagcttct tctgcgtttg tatcttcgac
     4381 tgtaatagtc tcaaatgaca aatccggctg aacgagtaga tatgcttttg caactgcaac
     4441 accgtcagat gctgcgattc ctttaagcat ttctgtcatt tcccttatgc caatccttct
     4501 ttttccattg tttctgagat tgcagcgata gcgtcatctg catctgcacc ttcagctgag
     4561 atagttacgt cagcaccttg accaacacca agactcataa cacccataat tgatttaagg
     4621 ttaactgatt tacctttgta ctcaagagtg atatctgaag caaatttgct agcagtttgt
     4681 accaacaatg ttgctggacg tgcgtgaata cctgtttctg ccactacgtg gaaatcttta
     4741 gaagccatag tttgactctc cttttgttct ttcttttttt gagttatatg tgataaccct
     4801 tacaatttag tattatacca tcttctagga tttttttcaa gcattttctg gattttcctt
     4861 caatttcctt tcagataact tgctgaaaat cttctatcct agataacaaa acacaggata
     4921 tagtttcttc aaaaacaatt tataggataa tcattgctat ttcacaatac aaacactata
     4981 tattgtgttt atatatgaaa acaacaaaag aacaccacta tatttagttt aaatcattga
     5041 caaaatttta ttttctgata tactaagata gtattaaatt ttgaagagga gttacacaat
     5101 ggtaaccgtt tattctaaaa acaattgtgt ccaatgtaaa atgaccaagc gtttcttgga
     5161 cagtaataat gtctcttatc gtgaaatcaa tcttgatgag caacctgagt acgtcgatca
     5221 agttaaagag ctcggtttta gcgcagctcc tgttatccaa acaccaactg aagtcttttc
     5281 aggtttccaa ccaggaaaac tgaaacaatt agcataatct tagtacatca tccagaagaa
     5341 actgctttta gggctaactt agaagccttt cttttgtaat tagataaggg aaattttatg
     5401 ggattaaaac atcttgaaga cgtgacttac ttccgtctta ataacgaaat taaccgtcct
     5461 gttaatggac aaatcatgct tcataaagat aaggaagcct tggatgcttt ctttaaagaa
     5521 aatgtagttc caaacactat ggtttttgat tcaatcaaag acaaaatcaa ttacctcatt
     5581 gaacacaact acatcgaaac agcctttata aagaaatacc gtccagagtt cttggaagaa
     5641 ttggctcaat ttatcaaaga ccaaaacttc caattcaagt cattcatggc agcttataaa
     5701 ttttacaatc aatatgcctt aaagactaat gacggtgaat actatcttga aaatatggaa
     5761 gaccgtgtct tcttcaacgc cctttatttc gctgatggga atgaagctgt tgcaatcgat
     5821 attgccaatg aaatcatcca ccaacgctac caacctgcta ctccttcctt cttgaatgct
     5881 ggacgtgctc gtcgtgggga gttggtatct tgtttcctaa tccaagtgac ggatgatatg
     5941 aactctatcg gacgttctat caactcagct cttcaacttt cacgtattgg tggtggtgtg
     6001 ggaattaccc tcagcaacct tcgtgaagct ggtgcaccta tcaaaggcta tgaaggagct
     6061 gcttcaggtg tcgttcctgt catgaagctt tttgaagaca gcttctctta ctccaaccaa
     6121 ttggggcaac gtcaaggtgc cggtgttgtc tacctcaacg tctttcaccc agatatcatc
     6181 gctttccttt caactaagaa agaaaacgct gatgaaaaag tacgtgtcaa gactctatca
     6241 cttggtgttg tagtacctga taaattctac gaattggctc gtaaaaatga agaaatgtac
     6301 ctcttcagcc cttactctgt agaaaaagaa tacggtgtgc cattcaatta catcgacatt
     6361 actgaaaaat acgatgaatt ggtcgcaaat ccaaatattc gcaagacaaa aatcaaggcg
     6421 cgggatttgg aaactgaaat ctctaaattg caacaagagt ctggctatcc ttatgtagtc
     6481 aacatcgata cggctaaccg tgcaaatcct gttgatggaa agattatcat gagtaacttg
     6541 tgttctgaga ttcttcaagt tcaagaacca agcttgatca acgatgctca agaattcctt
     6601 caaatgggaa cagatgtttc atgtaacctg ggttcaacca acgtggttaa catgatgact
     6661 tcacctgatt ttggtcgttc tatccgtgct atggttcgtg cccttacttt cgttacagat
     6721 agttcacata tcgtagctgt accaacgatt gaccatggaa atagccaagc ccacaccttt
     6781 ggtctcggtg ccatgggact gcacagctac cttgcccaac aactcattga atatggttca
     6841 cctgagtctg ttgaatttac aagcatctac tttatgctta tgaactactg gaccttggta
     6901 gagtcaaaca atattgcgcg tgaacgtggt attaccttcc acaactttga aaaatcagac
     6961 tatgctaacg gaagttactt tgacaagtat gtaactggtg aatttgttcc aacatcagac
     7021 cgtgttaaag aactcttcaa aaatgtcttt atccctggtg ttgctgattg ggctgaactt
     7081 cgcgacaagg ttcaagaaga tggtctttac caccaaaatc gccttgctgt agcgccaaat
     7141 ggttctatca gctatatcaa cgacgtttct gcttctatcc acccaattac gcaacgtatc
     7201 gaagaacgcc aagagaagaa aattggtaaa atctactacc ctgctgctgg cttgtctaca
     7261 gaaaccattc cttactacac ttctgcctac gatatggata tgcgtaaagt catcgatgtt
     7321 tacgctgctg cgactgaaca cgtggatcaa ggactttcac tcaccctctt catgcgtagt
     7381 gacattccaa aaggccttta cgaatggaag agggaaaata aacaaacgac acgtgacttg
     7441 tccatccttc gtaactatgc ctttaacaag ggaatcaagt ctatctacta cgtccgtacc
     7501 tttacagatg acggtggaga agtcggcgcc aaccaatgtg aaagctgtgt gatttagttt
     7561 ctatcataga aacactattt ttccctaagc agcactgata aaatcaaatc tactatgtca
     7621 taacataatt tatgtaacat tttaaaagtc gggcttccga ctttttgtgc gatactccta
     7681 tagaattatg gtaaagtaga aataattgtg agttcgcaat actaaacaca gaaagagatt
     7741 ttaaatggaa acttactaca aagccattaa ctggaatgcc atcgaagatg tcatcgacaa
     7801 atcaacttgg gaaaaactga cggagcaatt ttggctcgat acacgtattc ccttatcaaa
     7861 cgacttggat gactggagaa agctatctaa caaagagaaa gacttggtcg gaaaagtttt
     7921 tggtggttta acccttcttg acactatgca atctgaaact ggggttcaag cccttcgcgc
     7981 agacatccgt acaccacatg aggaagctgt tttcaataac atccaattta tggaatctgt
     8041 ccacgctaaa tcttactcat caatcttttc taccttgaat actaaggctg agattgaaga
     8101 aattttcgaa tggaccaata ccaatcctta cctacaaaag aaggctgaga ttgtcaacga
     8161 aatctaccta aacggcagcc cacttgaaaa gaaagttgcc agcgtcttcc tcgaaacctt
     8221 cctcttctac tctggtttct tcactcccct ctactatctc ggtaacaaca aactagccaa
     8281 cgttgcagaa atcattaaat tgattattcg tgacgagtct gttcacggaa cctacattgg
     8341 ttacaaattc caacttggtt tcaatgaatt gcctgaagaa gagcaagaaa aactcaaaga
     8401 atggatgtac gacctactct atactcttta tgaaaatgaa gaaggctaca cagagagtct
     8461 ttatgacggt gttggttgga ctgaagaggt taaaaccttc cttcgctaca atgccaataa
     8521 agctctcatg aacatgggac aagatccact tttcccagat tcagctgaag atgtcaaccc
     8581 aatcgttatg aacggtattt caacaggaac ttccaaccat gacttcttct ctcaagtcgg
     8641 aaatggttac cttcttggcg aagttgaagc catgcaagac gatgactata actacggttt
     8701 agactaattc tccatcactc tcaatcatca aaaagtaaac tagaaacatc aaagttataa
     8761 cccaacaaaa atatcgaaag ttttgaaaac aaacttcgat atttttgttt ttgtttcatt
     8821 ttgttgtttt tgtatttgaa tgatgagttt gtttatggta agatagtagt aggaaacgag
     8881 gtgataatat gctcaaacaa gaaaaattaa ccaaaatttt agagatagta aatagtaaag
     8941 gaaccataac agttaaacag attatggacg aaatagccgt ttcagatatg actgcaaggc
     9001 gctatttaca ggaattagct gataaagatt tgctgattcg tgtgcatggt ggagctgaaa
     9061 aacttcgaac caactccctt ttgactaatg agcgatcaaa tattgaaaaa caagccctcc
     9121 aaacggcaga aaaacaagaa atagcccatt ttgcaggcag tctagtagaa gaaagagaaa
     9181 ctattttcat tggaccagga acaacattag agttttttgc gcgtgagttg cctattgaca
     9241 atatccgcgt cgtaaccaac agtctacctg tttttctgat tttaagcgaa cgaaaattaa
     9301 cagatttgat tttgataggt ggaaattatc gcgatattac aggtgctttt gttggcacat
     9361 tgaccctaca aaatctctct aatctccaat tttctaaagc tttcgttagc tgtaatggta
     9421 ttcaaaacgg agctctagct acttttagcg aggaagaggg agaggctcaa cgcatcgctt
     9481 taaataattc taataaaaaa tatttactcg cagatcatag taagttcaat aagtttgatt
     9541 tttatacttt ttataatata tcaaatcttg atactattgt ttcagattct aaactaagtg
     9601 attcaatcct ttttaagcta tctaaacaca ttaaagtcat caagccttaa taaactgaaa
     9661 gagcctgggt aacaactcaa tttcagaaga aaaaaagtaa atcttcccac aataaaacgc
     9721 atagtatcag gtgtttcaac acctgatact atgcgttttt ctattcttca ggattgataa
     9781 aatttaaaaa tagattttta aattcttcca gatcatcatc tgaatgacaa atccattctt
     9841 taccagtcga gacataccat tttccaagac ttttcaattc ttcactcgtc aaacacggta
     9901 tttgagagca tttttcgaaa tttataatat aaactttttc ataaatagat tggataaaat
     9961 ctttgaacat ctttttgact cactaaaatt ctatatctaa tgactaattc tactagtcta
    10021 taatctgagt ttccgctact ttcttgtacc agtgagctga tttcttagga taacgttctt
    10081 gagtttcaaa atctacgtag aagagaccat aacgtttctc ataaccgttt gaccatgaga
    10141 agacatccat taatgaccaa atgaagtaac cttttacatt agctccatct gcaatcgcat
    10201 cagataaaac ctccaagtgt tgcttcacgt aatcaatacg tccatcatcg taaacagtgt
    10261 tatcaacgaa ctcatcttta tatccaagac cattttcagt gatgtagatt ttcttatagt
    10321 taggataatc tttcttcacg cgcatgattt ggtcatacaa accttgaggg tagataatcc
    10381 aatcccaatc cgtgcgtggt acatagtcag gagctacacg acgaccaata cctttgattt
    10441 ggtatttaga gcttcctttt tcacctttac cattatggat aatttcagtt tctccatcaa
    10501 aggcttccat ccagtcactc atatagtagt tgattcctag gaaatcattc aagtcttttg
    10561 cagcttctaa tgctgtaaaa tcttcttcac gaagatccaa gctaccacca ttggcagcca
    10621 agatagcctc tacccctgcc agagtctttt cagagtagtg acccagatag gttgcatcca
    10681 aaataaattt gttgtgaata atatcttcca actcagctgc acgaacatct gctggatttt
    10741 catgatctag aggatattta gtaggcaggg cgtgaacaac accaatttcc cctttatagc
    10801 ctttctcttt gtacaatttt accgcgcgtg catgagacac catcatattg tggtgtgatt
    10861 gaaagacttt ggcaaggtcg tactggatac ctggagggaa tttcccaacc aaatattgac
    10921 catcaccgat tggtccaatt tcattaaagg ttgtccaata gtttacttct ggaaattctt
    10981 caaaacagaa agcagcgtag tctacaaaat gttcgatatt ttcacggttt aagaagtctc
    11041 catttgagtg gagagcttct ggcgtgtcaa agtgatgaag agttacaaaa ggctcaacat
    11101 gacgtttgtg acactctgca aataaattat gataaaactc aacaccttta gcatttactt
    11161 ggccgtaacc agtcgggaaa atacgtgacc aagcaataga aattcgaata ccattgacac
    11221 catactcttc tgctagcttg aggtcaactg gatatcgatt gtaaaaatca ctagctggtt
    11281 cggcagtgta ccagtagtta tcctcaagat atttatccca agcaactggt ccttttccat
    11341 cagtatgtgt agcaccttct gcttgataag cagctgttgc gccaccgaaa ataaagtctt
    11401 ttggaagtgt ttttgtcatt tttttcacct atttcttgat ttaaataaag taaaagtgag
    11461 aggagaggag tcagtgagcc atgcttctcc atctcacttc ttgtaccaag tcactgaatt
    11521 gtgacatgag gaggtaaaaa cgatatcttt ttaccgacga attaataagg cgattaggaa
    11581 attcgccata gcgatttccg taacgatggg agactgtttc acagttccta gccttaatcg
    11641 aattgctctt gtacgaatgc tagggcacct tttccatcac gagttaattt gatgtattga
    11701 gcgccttctg tcttagcaag tttaataccg agcttatctg tttctgcctt catatcttca
    11761 aagtttgaag caacttgagg ggcaaggata actagattaa actctggtaa catttcacgg
    11821 tgagcaccat agccgcctgc tgctgctttc acagggacat tgtattctgc tgctgcctta
    11881 ttcaaagcat ttgcaaggag tccacttgta cctccaccag cacagagaac gaggacattt
    11941 gtttcttcag tgatggtatt ttgtgctgca tcgacacccg ctttttcaag aatagcatcc
    12001 gcttttgcag tgttgaagtt tgcagcaact ttttctttca attcatcatt agacttacct
    12061 gaacgttctt cttcaagaat ttgttcatca tagactttaa ggaatgggta ataaataact
    12121 acgtcaacca caattagaag ggcagcaaga atgaatgata gcacttggaa gttagttcca
    12181 agaactagac ctagtggagc tggagttgtc catggtagat tagcagtgaa tgagttcatt
    12241 ccaagagttt caataaagaa tttgaaaatc catacgtttg caattggagc aaagataaat
    12301 ggaatgaaga agattggatt caaaacaaga ggtgcaccaa acaagattgg ttcatttaca
    12361 ccgaagaagg taggaactac tgaagcacgt ccgattgcac ggttacgttt cgattttgtc
    12421 aaccacatga acataaatgg aacgaccaat gtcgcacctg taccacccat ggtaacgata
    12481 aacatttgtg taccagaagt aagaatcttg tctgcatgca tcccttgttg gagaaggttc
    12541 aagttaactt cggcattggc ataggtaata gctgcgatag ctggttcaac gatagatgga
    12601 ccatgaatcc caacaaacca gaagaaggca aaggcaccaa agataatggt aataccaagg
    12661 tatccgtctg ctgctgagaa gagtggtgcg aagaatttac cgattgattc tgccacacta
    12721 gaaccaacaa aataacgtgc taataagtca agagcataaa gagaaacaac agatagagtg
    12781 aatggaatca catctttaaa gacttgtgag atatttggtg gaacttcgtc aggcatacga
    12841 atagtgacgt tgttcttaac acaaacctta tagatggcta cagtaacaaa ggcagcaagg
    12901 aaggctgaaa gcaaaccttt tgtccccaag aatccagtag ctagaccact ttcgatagga
    12961 tcagctgcca acatcaacaa accaacaatt gctgccaaca atgttgacat atagttgatt
    13021 tgattggttt tttccatgct ccggtttact gagtcagtca atgacttagc tgttgtacca
    13081 gctaccaaga gagccagaat acccatagaa tagctataag gtttcatcag aaaggctaca
    13141 acttcatcag accatttaaa gccccatgag tttggtacaa aggcaatcaa gataaagata
    13201 cttgagaaga gaataacagg catacctgca atgaaaccat cacgaatagc acgaagatag
    13261 atattacgag atagtttttc aaagaaaggc tttcctttct cgataaatgc aattagttta
    13321 ttcattattg aactcctctc ttgtagagtt caattaaatg atgcatcaaa tcttttaaca
    13381 agatagttgt cattaagtgg tcttggccat gcatcatggt tacactataa gccaagtcct
    13441 cacctgaagc ttccttagtc aatagacttg tttgcgcgtg gtgagcctct gcaatacagc
    13501 taccagcttc ctctaccaga gcgtccgctt tttcaaaatc accagcttca gcagccttca
    13561 aggcttccaa tagttttgaa cgagcatcgc cagcataggc tacgatttca aaacctaaca
    13621 atgttacttc ttctctattc atgatagaat tctccttata tagttttaaa taaattttta
    13681 tgacaataaa cgttggatat gtagaactag ataaactcgt tcacttttat acaaatcaag
    13741 acccgtatgt tgcgtaatca catcatagat cttggaacca atctcgaagg cttttggata
    13801 ggattgttta atatgatctt ccatatccag aagtgattgg ttatcatctc tagatctgtc
    13861 taaataatcc aagaaataat tcaaatggat cataaagcga tcatagaaat ggttattctt
    13921 tttagttcgt tgaattgcat agtccgttaa aacttcttca acattcctga gaatttcttt
    13981 cctcttatca atcgactcca caagttccac ttcattttca ccttcagcat taatgaaatg
    14041 ataagcaatc cgaataattt cgtcctcagg aaaatgatct gctagcttct gacggtaaat
    14101 ttcaaaagct tcatttgcga tttgaaaagc gacaggatac ttagcggaaa tatctggcag
    14161 attactatcc ttgtaccttc cttgagttag agcttgataa gaacagtaaa tatgatctgt
    14221 caaggttaca tagagatact cttgaatcgg ataatgatat ttctttgata gcttatcaat
    14281 gatttcatag gtcactgtga taaaatcaag cggaacatct ttgagaagag ccataaagtt
    14341 ttctctggac tcttcggtct tcatccgaaa gattttctca acctgatttt cagcaatcaa
    14401 atcccccttc ttctttccga atgcaattcc cttaccaatt acaatcacct cttctccctt
    14461 atcatttctg acaagcgaga cattgtgatt cattggattt agaattcgat acatgtcaac
    14521 ctccttttat atcttaaagg tatataagta caaaaaatga ccacaaatga actagaaaat
    14581 cagctgattt ctaattcacc tgtgatcatg cctaatatta cttagtaaca ctcaccttgt
    14641 attaacttgt gatttaagta tagcacaagt aagttatttt gtaaaccttt acatacaact
    14701 ttttttaaat ttttttagat tcatgttcct aaactaggag gactttctta cacacgttct
    14761 ttccatgaag tcgctgttgt ttgaagaact ttattgagct catcaatgtt ttcaaatcca
    14821 gttgtgcgaa gccattcgcg agctgctgct tcaccatctt tgatgtaagc ttcaactgat
    14881 cctgcccatg tagcacggcc acaaagaact ccgttaaagt ttgcacctga ttcatgagca
    14941 aatacaagag tatcttggaa gagtttagct gatacaccag cactcaagta gatgtatggc
    15001 aagttcgttg cttcatcttg cgctttgaag aaggctgctg cttcttcacg tgtataaact
    15061 acttcacctt cagcgaagcc ttcaacatat ttaatgttaa caggaacttc aactttcaag
    15121 acatcaatgt taaagcgtgg gtctgaaaag actttcatag cgccgataac tttgtgtggt
    15181 tttactttcg cgtattctac agaacctgca tccgcaattt tttcatcgta agcaaggatt
    15241 tcaaggaaga atgggatatc ttcagccaca cactcagaac cgatgcgttc gatgtaggct
    15301 tgtttttctt gattgagttc gtctgagcta tctacatcat agtaaagcaa gaatttaact
    15361 gcatctgcac cttcttcttt aatacgtttt gcagaccaga catccaagca gtctggcaag
    15421 cgttttgtgc ttgttgtgtc ataacctgtt ttttcataag caaggagaag accagctttt
    15481 tcatcaagag ctttagttgc tggaagtcca tactcagggt caagaagcat agatgaagcg
    15541 tatttagtca attcatctgc taccaagact ttaagttctt ccatttgggc cacagttggt
    15601 tcttctgttt ggtgttgagc catgaggcgt ttcaaagcac cacgttggtc aaatgcaaga
    15661 gctgagatga taccattttc atcagaaagt ttttctaagc gtacacgttt ttgttctgtt
    15721 aaagccattt tatacctctt ttactattaa ttgatcatat agaacttgat agttggccat
    15781 gttgacatga ccagtcattt tttcttgagc attgagcata ccaaggacat ttgccttgat
    15841 gagtaattct gcatccgatt ctttgtgaag aagtcctgaa gaaattcctg ccacagtaga
    15901 gtctccagat ccaacaggat ttaccacctg aattctagga atatctacct tgtagaaagt
    15961 gtcaccatgt ttggcaaaag taccgttggc accaagtgaa acgataatcc attcaatccc
    16021 tgcaaacaaa ggttcttgaa gtacttcttt taattcatcc aaatcctcag aaacttctct
    16081 tccaagaagc tgagacaatt cttcattatt tggtttgatg actgttggtt tatggggtga
    16141 ttcaagaaca gcctgaagtg ctgcacctga gcagtccaag actacaggct tgccagcttg
    16201 attagcaagt tctaccaagc tcgcatagta atcaactgga aggccagctg gcagactacc
    16261 tgagatggcc actacttcaa ctgactccaa gagttttttg aaatgttcca aaaagtcttg
    16321 accttcctgt tccaatactt caggaccttt ttcaagaact tctgtttggt tgtctccgtg
    16381 gagaatagcg atacagttac gagtttctcc ctgaattgag aagaaatctt tctttacttg
    16441 attatcgata tgttcaacca aaaactcacc aagtttgcca cccactaaac cagtagcaag
    16501 aacagaatcg ccaaattctg aaagtactcg ggtaacattg agtcccttac caccagccgt
    16561 tttggttaca tccaccacac gattgacagt atcaatcttc aactcatcca agggatagga
    16621 aatatcaatg gatgggttca ttgtaactgt taaaatcata gtttacctct tagtcgtggt
    16681 agtctccgcg atcccatttt tcaaggaatt cagtgaagaa gtttgcgtct gtttgttgag
    16741 cattgtgact ttcaaggtgt tcaattttcg caatcaattt tttgttttct tcagatggtt
    16801 tgtattcagc atgaatgaaa gcttcgatga tatcacacat aagcaattca ccagtaatct
    16861 taccaccaaa accgataacg ttggcgttca attgttcttt agcataaagg gctgttgtca
    16921 tatcacgaac caaggcagaa cgaacacctg gaactttatt tacagcgttg ttgataccaa
    16981 caccagtacc acagatacat accccgagat cagcttgacc actagttact gcttccccta
    17041 cttttttacc aaagattggg tagtgagtcc gtgtatggtc atatgtacca aagtcaatga
    17101 cttcatatcc ttttgatttc aaaaattctg aaaccgccat tttttcatca gttacgatgt
    17161 ggtcacatcc aattgcaatt ctcattttta acttaccttt cttactataa tctaattagc
    17221 ccattttgtt caacatgtca acccggattt ggtgacgacc accgtcgtat ttaccattaa
    17281 caaatccttt agcgatgttt ttagccaatt catcaccaac aagttgtgcc cccatagtga
    17341 tcatacgtga gttgttgtgg ccacgagtca tataagctga acgttcgtca gatacttctg
    17401 cagcaaccat tcctttgatc ttagttgcaa ccataaatgg accagctcca taagcatcaa
    17461 tcacgatacc aaggttttgt tcttctttgt ttacttctgc agcaacagcg agagtcacat
    17521 caacaaagtc ttgaccttca gctgtaacat ccacaaggtg gaagttttct ttttctaaaa
    17581 agtctttcac aacttctttc aatctcaaac ctgcagcatc tgcaccgata acaatagaca
    17641 tattgtatac tcctttttat tttttctatg ctggattcca gcagtgtatt ggctgtcttt
    17701 aaaaaacagt caattagtcc tcacaaacat aatatactac tattgtttga agaagtcaac
    17761 agtttgtgtt tgtttttgtt atttattttt tactttttta taaaacttct atctcaaacc
    17821 ctaattcttc aacctgattg gcttctaaga gacaaacatt cttcttatct tctaaatgat
    17881 ctccttcttc aaggaatgtt gacaagccag accatggttc aaaggtaatg aaaggtccct
    17941 tgttcaaagt tgaccagatg atgaggtttg gaaattctgc aaaatgcact ttcaatccct
    18001 tatcatgttt aagagaacga agggcaattg ttcgagattg caattcatcc aaagtcactg
    18061 catctgtgct gaaaagatca taactaagat ctatttcttt ttgtccctct agccatggac
    18121 ttctatcttg gaaatccaac atacctgttt ctgggaaagg acgtggaaca gagcaaatct
    18181 cttctttctc aaactctaga taataatctt catagacttc atcatcaagt agaagacaat
    18241 taaatcctgg atgtccacca ataaagtaag gcctgacctt gctagtttct ttattagact
    18301 tcctgcaaaa ctagaatccg ataataccag caatcaaatt cattcgtaat ccgaagcgtt
    18361 tacgatgatt tcgataggtt gttgaaaaca ttttaaacgt ttttactttg gcaaagatat
    18421 tctcaacctt gcttctctcc ttagatagcg catgattaca ggctttatct tcaactgtta
    18481 gcggcttgag tttgctggat ttacgtggag tttgtgcttg aggatatatc ttcatgagcc
    18541 cttgataacc actgtcagcc aagattttac cagcttgt
//
LOCUS       DBERXF010000045        18295 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.45, whole genome shotgun sequence.
ACCESSION   DBERXF010000045 DBERXF010000000
VERSION     DBERXF010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18295
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.45"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(27..1706)
                     /locus_tag="ACL8JK_001765"
     CDS             complement(27..1706)
                     /locus_tag="ACL8JK_001765"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGS1786604.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(1708..1941)
                     /locus_tag="ACL8JK_001766"
     CDS             complement(1708..1941)
                     /locus_tag="ACL8JK_001766"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HGS1786605.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            2221..2436
                     /locus_tag="ACL8JK_001767"
                     /pseudo
     CDS             2221..2436
                     /locus_tag="ACL8JK_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2759..2911)
                     /gene="cibB"
                     /locus_tag="ACL8JK_001768"
     CDS             complement(2759..2911)
                     /gene="cibB"
                     /locus_tag="ACL8JK_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HGS1786606.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(2913..3098)
                     /gene="cibA"
                     /locus_tag="ACL8JK_001769"
     CDS             complement(2913..3098)
                     /gene="cibA"
                     /locus_tag="ACL8JK_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HGS1786607.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            3276..3959
                     /gene="tsaB"
                     /locus_tag="ACL8JK_001770"
     CDS             3276..3959
                     /gene="tsaB"
                     /locus_tag="ACL8JK_001770"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGS1786608.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            3956..4393
                     /gene="rimI"
                     /locus_tag="ACL8JK_001771"
     CDS             3956..4393
                     /gene="rimI"
                     /locus_tag="ACL8JK_001771"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGS1786609.1"
                     /translation="MIEIKRIQQQPDLAKAIYAVMIAVYPVSPWTLEQIQADLFQDQT
                     WYALAYDGAEVIGFLAVQETLFEAEVLQIAVKGAYQGKGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIADRKAYYHDPVEDAIIMKREIDEG"
     gene            4383..5393
                     /gene="tsaD"
                     /locus_tag="ACL8JK_001772"
     CDS             4383..5393
                     /gene="tsaD"
                     /locus_tag="ACL8JK_001772"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGS1786610.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(5433..6739)
                     /locus_tag="ACL8JK_001773"
                     /pseudo
     CDS             complement(5433..6739)
                     /locus_tag="ACL8JK_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(7078..7766)
                     /locus_tag="ACL8JK_001774"
                     /pseudo
     CDS             complement(7078..7766)
                     /locus_tag="ACL8JK_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8009..8563
                     /locus_tag="ACL8JK_001775"
     CDS             8009..8563
                     /locus_tag="ACL8JK_001775"
                     /inference="COORDINATES: protein motif:HMM:NF024831.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS1786611.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKK"
     gene            8691..9215
                     /locus_tag="ACL8JK_001776"
     CDS             8691..9215
                     /locus_tag="ACL8JK_001776"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS1786612.1"
                     /translation="MDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICH
                     LKCRDNFRLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNVGGLS
                     EIIEHRVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVET
                     MRVYDELLEKSSHG"
     gene            9208..10161
                     /locus_tag="ACL8JK_001777"
     CDS             9208..10161
                     /locus_tag="ACL8JK_001777"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS1786613.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLNDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYYFGFFYCIYDNYVQLKFRK"
     gene            10171..11787
                     /locus_tag="ACL8JK_001778"
     CDS             10171..11787
                     /locus_tag="ACL8JK_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1786614.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            12066..12476
                     /locus_tag="ACL8JK_001779"
     CDS             12066..12476
                     /locus_tag="ACL8JK_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786615.1"
                     /translation="MSKKISNLNDKKEFHKKNCELRFQDSVLDNINSVPGTTHLFSCL
                     NIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIERILKYL
                     YICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            12488..13237
                     /locus_tag="ACL8JK_001780"
     CDS             12488..13237
                     /locus_tag="ACL8JK_001780"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HGS1786616.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIIFWIKK"
     gene            13250..14421
                     /locus_tag="ACL8JK_001781"
                     /pseudo
     CDS             13250..14421
                     /locus_tag="ACL8JK_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            14816..15679
                     /locus_tag="ACL8JK_001782"
     CDS             14816..15679
                     /locus_tag="ACL8JK_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGS1786617.1"
                     /translation="MIERMELGEFYKELRLARKLKQTDVACEGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMRIGRKVVNRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKDAIHSLNKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFIQSLQVLENPQLTSLFE
                     LRFQQYKELID"
     gene            15970..16167
                     /locus_tag="ACL8JK_001783"
     CDS             15970..16167
                     /locus_tag="ACL8JK_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HGS1786618.1"
                     /translation="MLNLQFAETMELTEAELETVYGGEFGNNAVIPAGAWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            16235..16900
                     /locus_tag="ACL8JK_001784"
     CDS             16235..16900
                     /locus_tag="ACL8JK_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS1786619.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            16972..18198
                     /locus_tag="ACL8JK_001785"
     CDS             16972..18198
                     /locus_tag="ACL8JK_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS1786620.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         5674 a         2948 c         3746 g         5927 t
ORIGIN      
        1 gcgaagctga cgtggtttga agagtattat tcttcatctg gtgtgaggat catcgggatg
       61 atgatcggtt cacgttcggt attttcatag aggaaggggc gaatagcgtt gacaatggca
      121 ccattgacag attgcacgct agcatcctta tttttcagtg cgatacgaat ggcattgaag
      181 aggatacgct ggctttggcg aatcaagtcg ccagactctc tcatgtagac aaagcctcgg
      241 ctgaggatgt ctggaccaga tagaatcatc tgcgatttga agtcaacagt tgcgactgcc
      301 agaacgacac cgtcttcaga tagatcgcga cgatctttga ggacagctgc gccaatttca
      361 ccgatacgat ttccatcgac atagatatct tgggcgttga aatggcctgc gatacgagct
      421 gagtcagcag taagggcaag cacatcgcca ttgctcatga taaagatatt gtccttctca
      481 acaccagtat ccactgctag tccagcgtgg actttttgca tgcggtattc accgtggaca
      541 ggcatgaagt attttggctt aatcaagcag agcatgagtt tttgctcttg ctgaccaccg
      601 tgtccagatg tatggatatt gttcacttta ccgtggataa cttcgacacc agcttcagaa
      661 atgatgttaa tcagcttgtt gacgctagta gtgtttccag ggatgggact agaagagaag
      721 ataacggtat cacctggttg taattgtact tgacggtggg ttccgttggc gatacgagag
      781 agggctgcca taggctcacc ctgactacct gtacagagga taagaacttc tcctgcagga
      841 taatctttga tttcatttgg ctcgataaag gttcccttag gagctttgat gtagccaaga
      901 tcgattccgt tgacaatggc cttttccata gaacgaccaa agaccgcaat cttgcgtcca
      961 gtcttaacag cagcttctgt tgcctgctgg agacggaaga tatttgaggc aaaggatgca
     1021 aagatgatac gtccttcaat accttggata atcttcataa tggactgacc aacgactttt
     1081 tcagagttgg taaaggttgg tacttccgca tttgtcgagt cagacaggag acagagcacg
     1141 ccttcttcac caagcgcagc catacgatgc aagtccgcag gttctccaac tggagtaaag
     1201 tcgaacttaa agtcacccgt acagacgatt ttcccttgag gagtatgaat gacaatcccc
     1261 aaaggctctg gaatagagtg agtcgttcta aagaaagttg ccttgagatt tttaaaggtc
     1321 aactcggtgt tgtggttgat ttcgtaaagt ttggcgttgc gcaagaggcc gtgttcttcg
     1381 agtttcccac ggatcaaagc caaggcaagc ggtccagcat aaatagggac atttgcttgc
     1441 ttgagtagga acggaatccc accaatgtgg tcctcgtgtc cgtgtgtgat taaaacagcc
     1501 ttgacgcggt cgatattgtc tacgatgtaa gagtagtcag gaatgacata gtcgatacca
     1561 agcaagtcat cttctgggaa tttaatccca gcatcgacga tgataatctc gtcttggtat
     1621 tcaattccgt aagtgttttt cccgatttct cctagaccac cgatggcaaa aacgccgact
     1681 tcttcaggtt taagagtgta ggccatatta gaactccgta atttcgaagg cgccagtttc
     1741 tttttcgtaa tcgagcaatt tgtcagacaa gagttcgata tattcgatat tgtactctgg
     1801 gcgattttct tcgacaagtt ggcgagcagt gatacggccc tcaagttctg agctggcatc
     1861 gatgtctagg taaagcgcgc gtgttgtttc acggcgtggg ctacgttctt ttgtttcttg
     1921 ataaaaaact ttgtaaatca tatagttcct ttctatttac aggtcagctt attccaaact
     1981 tttagcagat atttgcttga tttcattcca ttttgtgtct agattgacct tgattcgtta
     2041 caattatttc aattatacca caaaatgaaa aattagtaaa agacggaaac gagaaagtta
     2101 gggggcaatt tctttggtaa gcgtttacaa aaataaagaa aatgtattat gttgataacg
     2161 gaagtgaaat ttattgcttg tcataattcc atatagattt taagtcaagg aggttgccct
     2221 atgtataact tatttgcttt tgctatcgga gttcgtttgt tagcttttat cgtttttgtt
     2281 gcttgcgttt atggaggaaa tcttccattt gccaaactgg aacgatgaca aaccaagttc
     2341 ttgtggaaaa ttacctttgt gactctctac tcgctttttc tcctcctcgt gccctatgtc
     2401 gtttggtttg tattttactt tggattaaat gcttagatgc cctgcttatg ctggggtttt
     2461 ttgtttgggg atgtagagat agtagattta cgacacgaaa attccacccc atctatcaag
     2521 atgaggtggt ctttgcattt ttctaacatg acatgacaat ggaattttca aagcttatta
     2581 tttttatggg agtcattgtt ctgctcaaaa atagagttga agcataaaaa taaaacaata
     2641 caaacagata aatcgaatgg taaagggata gtagtaatgt tcaaatcatt gagaatgctg
     2701 agcaaactgt aagagatgaa gacaataaaa tttatccttc taaaaatgtg tttcttatct
     2761 agcatgactt accaaacttt ttacgaaggt cttttccaat ggtataacct gccataaata
     2821 aagcgatacc aacacctaca ccaaagccac ccttgatttc ttgcaattcc ttattagaaa
     2881 tttcacgata gttgttcaaa tttttcatca tattaatctc ctcctaaaaa ataaccagct
     2941 gccaaaccag aacctataag tgctgttcca cctgcaatag ccttccaaga tactgctact
     3001 ccaaagataa ccaagggagc gagaccgcca tcaatatctg ataattcatt ttcagataag
     3061 gataaaaatt gattgtcaag aatgtcaaaa tttgtcattg aactttcctc cttttttctt
     3121 gttcactttt atattcggaa aagaaaagga aaagtgagca tttttttaaa ttatttttag
     3181 ttaagtgagg gcactcttgt ctgggggcaa agaaaattcc catgtgccag cttttgtagt
     3241 ataatagtaa gcagacaaaa agataggaat gtgttatgaa agtattagct tttgatacgt
     3301 ccagcaaggc tctttctctg gctattttag aggataagca ggttcttgcc gagacgacga
     3361 ttaatattaa gaaaaatcac agtattactc ttatgcctgc catcgatttt ttgatggcaa
     3421 gtttggattg gacacccaag gatttggacc gaatcgtggt agctgaaggg ccgggtagct
     3481 atacaggctt gcgaattgcg gtagcaactg ctaagacctt agcttacacc ctgaacatcg
     3541 agttggttgg tatgtcgagt ctcttggctc tggtgcccca ccaacaagaa ggtttgtttg
     3601 tccccttgat ggatgcgcgt cgcaataatg tttatgcagg attttatgaa aatgctaaac
     3661 ctgtcatggc agaagcgcac ctatcttttg aagaggtgct agaaaaagtc aagggtacta
     3721 gtcaggtaac ctttgtcgga gaagttggcc cctttgttga gcagattcaa aaacacttgc
     3781 caaggactga ttacaaagaa acattgccca atgcagctaa tctagctctt ttggcctggg
     3841 acaaggaagc agactccttg catgattttg tgccgaatta cctcaaacga gtcgaggctg
     3901 aggaaaactg gctcaagaac cataccgagt ctggtgagtc ctacattaaa cgcctatgat
     3961 agaaatcaaa cgaatccaac agcagcctga tctagctaaa gccatctacg ctgttatgat
     4021 agctgtttac ccagtcagtc cttggacgct ggaacaaatc caagctgacc tgttccaaga
     4081 ccagacttgg tatgctctgg cttatgatgg ggcagaagtg attggctttc tagctgttca
     4141 ggagactctc tttgaagcag aagtcctgca aatcgctgtc aaaggagcct atcagggtaa
     4201 gggcattgcg tcagccttgt ttgctcaatt gccgacagat aaggagattt tcctcgaagt
     4261 cagaaagtca aatcaacgag cgcaagcatt ttacaagaaa gaaaaaatgg cggtcatcgc
     4321 tgatcgaaag gcctactacc atgacccagt cgaggacgcc attatcatga agagagaaat
     4381 agatgaagga tagatatatt ttagcatttg agacatcctg tgatgagacc agtgtcgccg
     4441 tcttgaaaaa cgacgatgag ctcttgtcca atgtcattgc tagtcaaatt gagagtcaca
     4501 aacgttttgg tggcgtagtg cccgaagtag ccagtcgtca ccatgtcgag gtcattacag
     4561 cctgtatcga ggaggcattg gcagaagcag ggattaccga agaggatgtg acagctgttg
     4621 cggttaccta cggaccaggc ttggtcggag ccttgctagt tggtttgtca gctgccaagg
     4681 cctttgcttg ggctcacgga cttccactga ttcctgttaa tcacatggct gggcacctca
     4741 tggcagctca gagtgtggag cctttggagt ttcccttgct agccctcttg gttagcggtg
     4801 ggcacacaga gttggtctat gtttcggagg caggagatta caagattgtt ggggagacac
     4861 gagacgatgc agttggggag gcttatgaca aggtcggtcg tgtcatgggc ttgacctatc
     4921 ctgcaggtcg tgagattgac gagctggctc atcaggggca ggatatttat gatttccccc
     4981 gtgccatgat taaggaagat aatctggagt tctccttctc aggtttgaaa tctgccttta
     5041 tcaatcttca tcacaatgcc gagcaaaagg gagaaagcct gtctacagaa gatttgtgtg
     5101 cttccttcca agcagcagtt atggacattc tcatggcaaa aaccaagaag gctttggaga
     5161 aatatcctgt taaaacccta gttgtggcag gtggtgtggc agccaataaa ggtctcagag
     5221 aacgcctagc agccgaaatc acagatgtca aggttatcat cccccctctg cgactctgcg
     5281 gagacaatgc aggtatgatt gcctatgcca gcgtcagcga gtggaacaaa gaaaacttcg
     5341 caggctggga cctcaatgcc aaaccaagtc ttgcctttga taccatggaa taaagagtgg
     5401 ctctttgtca agtgtagtgg gtaggcgaaa agctacaatc tggagagtac gaaattcgta
     5461 ctctcttttt tgatgttcaa agtcatcaaa atccgttttt taaaattgtt aaagttccgg
     5521 aaaccaaagg ctttgcgctt gataacctta atcaaattat tggtcgcttc aagtttagcg
     5581 ttggaataag gcagcttaag tgcgttgata atcttatctc tatcccttaa aaaagtccaa
     5641 aagaccgttt gaaaaagcgg atgaaccgtt ggcagttctt gctcaatcaa tccaaagaaa
     5701 tggtcggcat tcttctcttg aaaatgaaag agcaggagtt gatagagttc gtagtgaacc
     5761 tgtaatccct cagagtaaga aagcagctta tctcgtactt cccgatgggt taagtgcatt
     5821 cgaaacgtgg gctgatagaa tcgtttctga cagagcttga agctatcctg gtgtagtaaa
     5881 tcagtccagt ggactgattt agcccgagcc tagaaacgaa aaagcgaggg ttccaaaagc
     5941 gcttgagcgc ccgatactcc aaggattttc ggtcaaattg gttcatgatt tggattcgta
     6001 ctcggttcat agctcggctc agatgttgga caatgtggaa gcggtcaaga acaatcttcg
     6061 cctttggaaa gagttgctta gcgagccgat aataagggct gtacatgtcc atggtgatga
     6121 cctcgaccag ctcccgaacc tctctctgat agcgttggaa atggtttcga atcaccgcat
     6181 gagttcgccc gtctaaaatt gcgaggatgg atttggactc aaaatcttgg gcaatgaagc
     6241 tcattttgct ctttttgaag ctatactcat cccaactcat aacttttggc aacttggtcc
     6301 aatcggtttc aaacttaaat tccctcagtt ttcggatgac ggtggaagtt gagaccgcca
     6361 atctgtgggc aatctcagtc atagactgct tttcaaggag gagctgagcg attttttgtc
     6421 tcaccatgtt ggaaatctgg caatttttct tgacaatgga tgtttgagaa acgaccacct
     6481 taaggcaatt cttgcactga aagcggcgct ttttgagatg tagtaccgtg ggtaaaccct
     6541 gacagtcgag aagcggaatt ttagaggctt tctggaagtc gtatttgatc atcttccctt
     6601 gacaatgagg acaaggagga gcgggggaat ccaactttgc ctgaacgact agatgggttt
     6661 ggtatttcag aacagacaag attttgatat ttttgtcttc caatccgagc aaatctgtgg
     6721 tattcttaag ttgttccata tgaccccttt ctaatgagtt ggttagacgc ttttcattat
     6781 aggtcatatg gggctttttt tctacaagaa acgaccctat aattcctggg gtgggattac
     6841 ccactacaga aattatagag ccaaaacatt ccaaagtctt gtctgactct ggaatgtttt
     6901 ctgttcacag ttgttttgta actgcctaat aagtaaccgc gctataacga ggtatctacc
     6961 gagattgtca attctccagt atactgttat aaaaaacaaa actggaggat ttttttatgt
     7021 ccccccatcg tcccatcgac tgttccgtag ctgcccaata acggagtata gtcgtctgaa
     7081 acaagaatag gacaaaagtg cctcaagaaa agcatcgtaa tttgacaata ttattctgag
     7141 atgtttttga tgtaagccca tattttctca atgggattat actcgggtga ataggtagga
     7201 agtggtaaca gtctatgccc tgctccttac acatgttcat tctgtgaaac cttgcattgt
     7261 ccataatgat aagggatggt gtatctaaag taggtagtaa gaatttttgg aagcaagctt
     7321 cgaaaaagtc actcgtcatc gtatctttat aggtcatcgg agccatagta tattgaaaca
     7381 aaaaagggta ttagtacttc tataacagta tcgcaatctc tggtgtgcgt tgtctcgatc
     7441 ttaattcaaa taattatatc ttcttccaga gagactaact gcctgctcaa ggatcaatca
     7501 tattcgagat aaaaataggt ctcaacccct gtctcataaa tataaatagg agtcaggtag
     7561 cttaagtgat tcaattcttt aaggaaccga tttacttttt ctgggtcttg ttcgcagtag
     7621 gtacagctct tttttagact atatcccata gcctttagag cgtaatgaat agttgttgga
     7681 ggacagttga attcagcagc tatttcagtc aaataagcat cgggatgagt ttcaatatag
     7741 atctttaatt tatctctatc aactttttca attaatagtg gaagttttct tgaagttagt
     7801 gtattgaaac gtttttatac agtgctaaaa tttgaagtgt agtgcagatg tatttgtaat
     7861 agtattatag caattctttg gagaaggtcg agacaagaga aaataggtat ctttgagata
     7921 taagcatgat ttactataaa attattgagt tattcataaa aatttctcta tcaaatatca
     7981 taatgcgtcg tttaaggaga tggttacaat gcaatatagt tgtggaaaaa taaatattaa
     8041 tatccctgat ggatatggag acattaagga tatagtgttt tcggctcata ttatagttag
     8101 gtataataat ggacattgtg gaggtataga tccgcatata attggacttt gtaaaaagca
     8161 gatcagaagg atgtctctat atcctatttt gataatcgta tctagagatt caaaggttat
     8221 tgatgattat aaaaatttag atattgccta tgttgattgt actcaatgtt caaataattt
     8281 tgaaactgcc ttacacgtta aaaatatttt aaaattatta aaaatccaac ttatacactg
     8341 tcatggctac tcaactaatt attttttata tatgttaaaa aaacttgaca agaatggatt
     8401 tggaaaggtt aagacagtga taacatgcca tggatgggtt gaatataact taaaaaagaa
     8461 attcttgact tattttgatt tttggacata ttctatggga gatgctttta tttgtgtatc
     8521 tgaaactatg aaaaaaagat tggagagtat aataaaaaaa taagaagata gttgcaataa
     8581 ataacggaat taatgtatca aatagcgatt tagatgtagt aggtgttcaa gactttaaaa
     8641 aagaattttg tattccaaat aacaaaaaaa tcatttgtta tgttggaagg ttggatccag
     8701 aaaaaaggcc ggatagattc cttgaatttg cagaaaaatt atttttagtc agagaagatg
     8761 tgatttttat tatggctgga aatggtagta tgtgggctgc tttgaaagaa aaaatttgcc
     8821 atttgaaatg tagagataat ttcaggttac ttggtgaaat ctatccagct actatagttt
     8881 accaaatatc ggatttattg tatattcctt ctgatacaga aggaatacct atgtgtgttt
     8941 tagagtcaat gtcacaagga actccggttt tagctagtaa tgttggcggg ttaagtgaaa
     9001 ttattgaaca tagggttgat ggatttttat ttgagaagga agatgttgag ggagtgtgtg
     9061 cttgtgctaa ttttttactc aatgattctg agtatttgaa atatataggt gagaatagta
     9121 aatcaaaaat aagaaaacat ttttctgtgc aaaaaatgtt tgtagaaacc atgagagtat
     9181 atgatgaatt attagagaag agtagtcatg gataggaata tagatcaaga attagtaagt
     9241 attataatac caacacataa taggtatgaa tctctgatta gagctgtgaa aagttgttta
     9301 catcaaagtt ataaaaatat cgaagttata attattgatg ataattatag taatgtaaat
     9361 ttaagaaata aaattatcca tcaatttggc tataccaatc atagaattaa gttaatttta
     9421 agtaatgaag atttaggtgc aactaatgcc agaaacatag gtatcaaaaa ttctagaggt
     9481 aagtatatat catttttaaa cgatgatgat gaatatatgc cagatcgaat tttaaagttg
     9541 atggcttgtt ttaaaaagag tagaatgaag aatttagctt tagtttatag ttatggaata
     9601 ataatttatc caaatggtac acgagaagag gagaagaccg attttgttgg aaatcccttg
     9661 tttgttcaaa tggttcacaa tatagcaggt acgtcatttt ggttgtgtaa aaaagaggtg
     9721 ctagaattaa ttaatggttt tgagaaaata gattcacatc aggacggtgt tgttttatta
     9781 aaactacttg ctcaaggata ccaaattgat atagtgcgag aattcttggt gaattactac
     9841 gctcacagta aagaaaacgg tatcactgga gtgacacaaa aaacaattaa tgcagatgaa
     9901 gaatattata attactgtag gaaatatttt aatttattga gtttcaacga gagaatattg
     9961 gttacaaaga aatattattc tttaaacata aagcggttac tattaatagg agacaaatgc
    10021 aaggctttaa aagtaatcaa gaaggcaaga gaagaaaaaa tttttaacga atttcttttt
    10081 ttgaaataca tgttattata ttattttggt tttttctatt gtatatatga caactatgtt
    10141 caattaaaat ttagaaagtg agaaactatt gtgtatacta ttataaaatc aaatataaaa
    10201 aaatttagtt tattaacgat atttattgtt gctggtcaat tattgctaat ttatgcagca
    10261 actattaatg ctctggtgtt gaatgaatta attgcgatga atttagagcg gtttttgaaa
    10321 ttgtcaatct accaaatgat tgtctggtgt gggataatat tccttgactg ggtagtgaaa
    10381 aattatcagg ttgaagtgat ccaagagttt aatctagaga ttcgaaatag agttgccaca
    10441 gacatctcta actctaccta tcaagaattt catagtaaat catcaggaac atatctttcg
    10501 tggctaaata atgatgttca gactttaaat gatcaggctt ttaaacaact ttttttagta
    10561 ataaaaggaa tttctggtac tatatttgca gttgtgactc ttaatcacta tcattggtca
    10621 ttgactgtag ccaccttgtt ttcattaatg attatgctac ttgtaccaaa aatctttgca
    10681 tcgaaaatgc gagaagttag tctaaattta actagccaaa atgaagcttt tttaaaatct
    10741 agtgagacta tattgaatgg atttgatgtg ttagcgtcct tgaatctttt atatgtattg
    10801 cctaagaaaa ttaaagaagc aggaatttta ttaaagatgg ttatacaaag aaagacaact
    10861 gtagaaacgt tagcaggcgc tattagcttc tttctcaata ttttttttca gatatctctc
    10921 gtttttttaa caggctatct tgcaataaaa ggaatagtga aaattggtac tattgaagca
    10981 ataggagcac taacaggtgt tatttttaca gcgctaggtg aattaggagg tcaattatcc
    11041 tctattattg gtacgaagcc tattttttta aaattgtatt caattaatcc aattgagtca
    11101 aataaaatga atgatatcga accaaatgag gtgaatagag attttccgtt atatgaagca
    11161 aaaaatattt gctataagta tggagataaa gaaatattaa aaaacttaaa tttttgtttt
    11221 caacgtaatg aaaagtattt aattttaggt gaaagtggaa gcgggaaatc tacattatta
    11281 aaattattga atggcttttt gagagattat agtggagaat tgcgattctg cggggatgat
    11341 ataaaaaaaa cctcctattt aaatatggtt tcgaatgttc tatatgtaga tcaaaaagct
    11401 tatttgtttg aaggtacgat tagagataat attttattgg aagaaaatta tactgatgaa
    11461 gaaatactac agtctttaga acaagttggt ttgagtgtaa aagattttcc taataacatt
    11521 ttagattatt atgttggtga tgatgggaga ttactgtcag gagggcagaa acaaaaaatt
    11581 actttagcta gaggcctaat tagaaataag aaaatagtat taattgacga gggaacttct
    11641 gctatcgata ggagaacttc gttagcgatt gaacgtaaga tattagatag agaggatttg
    11701 actgtcatta ttgttaccca tgctccgcat ccggaactta aacaatattt tactaagata
    11761 tatcaatttc caaaggattt tatttaagaa tataggggag ggaaacatga gattctattg
    11821 tgaagcttat gaggtaatta ctgaagagaa aaaagtatca tttttttatg tagatgagaa
    11881 acccttaagg tatctgttat ttgactatat atttctacta gttctagcta aaaaaaaata
    11941 tcccaatctt atgaactgca ccccaaaagt tagatttatt ctgtctaact tttggggtgc
    12001 agttcatttt gcatagtttt ggcattcatc ctagatatcc atataaaatg tctgagattg
    12061 ttgaaatgtc taaaaaaata tcaaatctaa acgataaaaa agaatttcac aaaaagaact
    12121 gtgagttgag gtttcaagat agtgttcttg ataacataaa tagtgtcccg ggtacaactc
    12181 atttatttag ttgtttaaat attcaaacat tagtaaaaat tattttatat atttttcgat
    12241 acaacagttg tatgaaaata tttaatttta gagataaaga gcttatcttt tttaataaga
    12301 ttgtaaatgg gctgatacaa aatattgagg agaatttaga ggatgatatt gaaaggatat
    12361 tgaaatattt atatatatgt ttatttaacg aaatattcat tattaagaat aaggtgaatt
    12421 tttttgatga tgtggaattt aatcagacac ttagtgagtt tttagataaa ttgtagaggg
    12481 aatggttatg agtaacaata ctaagtatat ctttttatct ccacatttag atgacgcaat
    12541 tttttcctgt ggtgattata tttcaaaatt aacttcagaa ggagaaattg tacttgttat
    12601 tactatattt tctggttacc ctttgagtca acagctacag ccctctgcta agcaatttca
    12661 taagttgtgt aaccttggga aatatccgat tgaagaaagg aagaaagaag ataggttagc
    12721 ttgtgaacgt ctacaatgtg attttagaca cttatcgtac tatgaatgtc tctataggaa
    12781 agatagaaat ggcaattttc tataccgtca tatctatagt gaattaaaaa atgaggacac
    12841 attaaagaat gatatcataa aagagctgtt aatgcattta gacgacaaat gtgtcgtata
    12901 ttgtccgctt tcacttggtg accatgttga tcatgttttt gtgaatagta ttggaagggc
    12961 gcttgaattt atgcgttata aagtaatata ttatgaggat ttcccatatg taagtgatag
    13021 tagtatggtt agttatatgg gaaaaactaa agaattaaaa atgtatcaag aggaactcga
    13081 tgaaaaacat tatattgata gaatatcatc aatattgtgc tataaatctc agattttgat
    13141 aatctggaaa tcagttgaaa aacttttaaa caatattaaa gagttgtatt taaggaatgg
    13201 ggcagcttat tctattatat tttggattaa gaaataagga agtagtttta tgaatatagc
    13261 agtaattggt ttggggcatg ttgggctggc ctacgcgtta ctatttgcat ctaaatataa
    13321 agttgttgca tatgatatag attctgtaaa aataaataat ttaaaaaagg gcattcttcc
    13381 atctaaaaat gaagagctta tgaagttttt ttgcgagaat aacttaaata ttactttttt
    13441 tgatacattt tctgaaatta aaaataatat tgattattat attattgcgc ttccgacaga
    13501 ttatgatgag aaaattggta gttttaatac atatgaaatc gaacaaacgg tatcgaagat
    13561 tctgagggta aaacctaatg gaaagattat tttaaagtca acagttccga tcggcttttc
    13621 aaacaaatta aaaaggctgt ttgatacaaa aaatatcatt tttgtccctg aatttttgag
    13681 agaaggttgt tctatatatg ataatttata tccaagtcgc atagttgttg gagatgagac
    13741 agttgaagga agaaaaattg cagagttgtt cctttcgatt agtactcata gtactgccaa
    13801 tattaaaaat gttatgttag tttctcctac tgaagcagaa gcaattaagc ttttttctaa
    13861 cacattctta gctctccgtg ttgctttttt aatgaactag attcttttgc tgagaggaga
    13921 agcttaaatg ctgaagttgt aataaaaggt gtttgtttag atccaagaat tggaaatttt
    13981 tataataatc cttcttttgg atttggagga tattgtcttc ccaaagatac taaacaatta
    14041 aaaaaagaat ttatagaaat aaatgcccca gtgatagaag cgattgatat ttcaaacaca
    14101 aatagaaaac agttcatagt taaacaaata ttggaacgaa agccaaagat agtaggaata
    14161 tataaattgg ggatgaaata taattcagat aattacaaag agtcagctat tttaagtata
    14221 attaatgaac tattgattgt cggtataaaa attttagtat atgaaccaaa tttaaacgtt
    14281 agtatagata acgtaattat tgaaaagaat tttgaactat ttacaaaaca aagtgatcta
    14341 attgttgcaa atagatggga taggggcctt gaagcttata aagataaagt ttacacaagg
    14401 gggatctgga taagagatta actattgata ttaaaaaggc aataatttat aaaatttgta
    14461 caaaaaaatg ttaaattttc acattttcat agtatactgt ttaatagaaa gtaggttctt
    14521 tgtaaccgct ccattataaa atcctttcac tcttccggta tactattagg aaaaacataa
    14581 ctggaggata ttttgagctc acacctcatc gttccagtgg ctgttcccca agctcgtgta
    14641 ctgcccaaaa aagttagaca ttctatttag aacgaggatt gagttctgta ttgtacaagg
    14701 ctcggtcctt ttagagtcag cttaaggctg gcttttttgc cctcttaaat atcagaatat
    14761 tttgacaaat gattgtaaat aatgatataa tatgcaaaag ctaggaggtg gtcagatgat
    14821 tgagagaatg gaactggggg aattttacaa ggaattacgt ttggcgagaa agcttaagca
    14881 gacagatgtg gcttgtgagg gtctaacagc ttctcagttg tccaagtttg aactagggca
    14941 gtctatgctg tctgcggata agttgattct agctatccaa ggtataaatg tgacctttga
    15001 tgagtttggg cacaagctca acaactatca agaatctcca catatgcgaa tcggtcgaaa
    15061 ggttgtgaat cgctttgccc atcaggatat agctgcttta gagcagctat tggaggaagt
    15121 cgatcaagaa cagatggcgc agacctatcg tcgtttgaat gccatcgtga ttaaagatgc
    15181 catccattca ctaaataaaa gctacccact agcagaggag gatagcgagt ttttgaccac
    15241 ctatctctat gctatcgagt cttggacctg gtttgaactc tatctctttt gcaataccat
    15301 gcccttcttg agcaatcaag atctgatttt tttatcaacc tccttactcg aaaaatccaa
    15361 agaatttaaa gagttagtac acaatcgatt gtatatgaag caaggactct taaatatctt
    15421 atcagaactc atggagcgaa aacttttctc ctacatccca atcttcgaag ccgagttgga
    15481 gaggatgtta cgaccgtatg atgtttttga aaaagtatcg tggcaatttt taaagaagat
    15541 gagtgtcttt cttcaaacaa agggaagcaa tcaaaaagag attgaacgct ttattcaatc
    15601 tctgcaggta ttagaaaatc cacaattaac atcccttttt gaattgcgtt ttcagcaata
    15661 taaagaactt atagattagt taaaaatgga atgacaataa cccactccga aataagtagg
    15721 agtatcagtt ggatttttct tttcttcatc tattatattc ctccttgtta gtaataactt
    15781 tattatacca gggaaataat caaatctatc aaaatcgcaa ataagaaatt tctataagaa
    15841 aaaatatcaa atatgcgatt ttttaaaata agccaatttt cgtgttatac tgtacttgta
    15901 aagcacttga agcaaatcct aggtcgcaga agtggtttac aaatgaagat aattgaagga
    15961 gtgtaaaaga tgttaaattt acaatttgca gaaacaatgg aattgacaga agctgagttg
    16021 gagacagttt atggagggga atttgggaat aatgctgtta tcccagccgg tgcttgggga
    16081 ggtttaggaa cgtcttggtc aatcactaat ttctggaaga aatattttaa ccatgattct
    16141 tccactgtta atcgtcgcca ttattgatat tcagagtcct tgcctttttc ttgggtaggg
    16201 actgtcttta tttcatagta taggagaaaa tagaatgaaa aagataatct cacaccgcta
    16261 ctttattata gtttttctac tagttattgc tgaccagaag ttcagtgttt tagttttacg
    16321 cagcgacctt gttgctgggc tatctgactt tgcctattat ctgtcggata tgatgttgaa
    16381 ttttcttgtg gttttatttg ctcttattgc tatgatttgg tcggggaaat ggcagaaaat
    16441 caatagtaga aagtttaaag gatcctatct tttctattcc ttcctagctc tgcttgcttt
    16501 tgttgcttgg aattttgtca ccttttttct tttcccacct actcgaaatg aaatttctta
    16561 tcaacatgct gctcctactt ttacaggagc tacggcattt ttgatgtatt ttttttatcc
    16621 tgtgattgca ggtcccattt ttgaagacat gatttatcgt ggattagtga tgactgctct
    16681 ggaaaaagga aagaaatggg ggctagatgt acttggttcc gctgttttat ttggggtctc
    16741 gcacattagt aatcacggtt gggtcttgac agactttgtc ttctatatgg gtggaggtct
    16801 tatatttgca gtcttattta gaatgacaaa gtcaatttat tggcctattg gactgcatat
    16861 agtctacaat ggcattggtc agcttttgat gttactgtaa ttttggttgt tagtagtatc
    16921 gcggtctatc cttggggaaa gattcccatt tgaacttaag aaggagttgt gatgaaagta
    16981 tttcttcaaa atagagattt taggcaatta actatcaacc agtggatttc aacgcttggg
    17041 gatacgattt tttatctggc ctttctgaat tatgtggcag atgcgtcttt tgcacctttg
    17101 gcgattttac tcattacgat ttcagaaacc cttccccaaa ttttacaaat ctttctggga
    17161 gttttggcag attttcaaca tcatcgtgtc ttgaaataca cagtcattag ttttgcaaaa
    17221 tttttgcttt actctatcgt ttctttatca ctttcagggc agtctttctc cttgttgcta
    17281 gtagcattta tttgtctgct taacctcttg tctgacacat tgagttactt ttcaggagcc
    17341 atgctcactc cgattttcat tagaattatt gggcaagacc atctggcaga agctattgga
    17401 tttaaacagt caactgttag tttagtgaaa acaatcagta atattctagg aggagtcttg
    17461 ctagggattc tctccatcca gttcatttcc ttgctgaacg ctcttacctt tttaatcgca
    17521 tttttaggta tcctcttcat aaaaactgac ctcttgaaag tagaaaaaac gattaactat
    17581 caagaaggac tctctgtaaa atccttttgc cagcatttgc tccaatcatc gaaattgata
    17641 tggaatatga ataaggtgct cttggttttg tttattatct ctactagtca agcagtgata
    17701 aatgttacag ttcctgtctc tactctattt ttgaggaatc aacccttttt gaatttacaa
    17761 acaggtcaat ctcttgcctt gctatccact tttgaactgt cagccctgat tgtcggaagc
    17821 cttgtaagtg gctatctgca acataccatt tccataaaaa cagctctcta tgcctcactt
    17881 gtcatccagt tgcttcttct agtaggattt gccacagttc gttttgactg gattctcatc
    17941 tttagtacct tggatgcctt tttcgcaggt gttctctctc ctagattgca agaactcgtt
    18001 tttaaacaaa tacctgagga gtcaatggga gcagttcaat cctctatcgg tgccattacg
    18061 gttgttttac ctagcttatt tacaatagct ttggtaacca ttgctactag ctttggaact
    18121 ctggcagtta gctttgtttt attgctattt cttctagttg cctttgttat gcttctgaat
    18181 attcgtgaaa gtatttagtg gagaatttct ataatatatg tttgagactg gattgccagt
    18241 ctttttatga tggtcaaaat caacagactt ttttctcttt tctgaatgtg ttata
//
LOCUS       DBERXF010000046        16695 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.46, whole genome shotgun sequence.
ACCESSION   DBERXF010000046 DBERXF010000000
VERSION     DBERXF010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 16695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16695
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.46"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            59..637
                     /locus_tag="ACL8JK_001786"
                     /pseudo
     CDS             59..637
                     /locus_tag="ACL8JK_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(736..2358)
                     /gene="groL"
                     /locus_tag="ACL8JK_001787"
     CDS             complement(736..2358)
                     /gene="groL"
                     /locus_tag="ACL8JK_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGS1786621.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEVTGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(2374..2658)
                     /gene="groES"
                     /locus_tag="ACL8JK_001788"
     CDS             complement(2374..2658)
                     /gene="groES"
                     /locus_tag="ACL8JK_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGS1786622.1"
                     /translation="MLKPLGDRVLLKIEEKEQTVGGFVLAGSAQEKTKTAQVVTTGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2814..3209)
                     /locus_tag="ACL8JK_001789"
     CDS             complement(2814..3209)
                     /locus_tag="ACL8JK_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGS1786623.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3287..4048)
                     /locus_tag="ACL8JK_001790"
     CDS             complement(3287..4048)
                     /locus_tag="ACL8JK_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS1786624.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEALKA
                     EFAETFPNQTVWTFLLDVTDMTIVKTVCSDILETIGQIDILVNNAGLALGLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKANQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(4081..4707)
                     /gene="ytpR"
                     /locus_tag="ACL8JK_001791"
     CDS             complement(4081..4707)
                     /gene="ytpR"
                     /locus_tag="ACL8JK_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGS1786625.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNMERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(4723..5040)
                     /locus_tag="ACL8JK_001792"
     CDS             complement(4723..5040)
                     /locus_tag="ACL8JK_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGS1786626.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(5037..5336)
                     /locus_tag="ACL8JK_001793"
     CDS             complement(5037..5336)
                     /locus_tag="ACL8JK_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HGS1786627.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATFYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5534..5731)
                     /locus_tag="ACL8JK_001794"
                     /pseudo
     CDS             complement(5534..5731)
                     /locus_tag="ACL8JK_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724444.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(5973..6647)
                     /locus_tag="ACL8JK_001795"
     CDS             complement(5973..6647)
                     /locus_tag="ACL8JK_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786628.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(6653..7099)
                     /locus_tag="ACL8JK_001796"
     CDS             complement(6653..7099)
                     /locus_tag="ACL8JK_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS1786629.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(7213..7716)
                     /locus_tag="ACL8JK_001797"
     CDS             complement(7213..7716)
                     /locus_tag="ACL8JK_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGS1786630.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7713..8075)
                     /locus_tag="ACL8JK_001798"
     CDS             complement(7713..8075)
                     /locus_tag="ACL8JK_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HGS1786631.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(8141..9172)
                     /locus_tag="ACL8JK_001799"
                     /pseudo
     CDS             complement(8141..9172)
                     /locus_tag="ACL8JK_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155117.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(9179..10000)
                     /locus_tag="ACL8JK_001800"
     CDS             complement(9179..10000)
                     /locus_tag="ACL8JK_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1786632.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQGTNLDELWQPA
                     SMMMGMLFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLT
                     RTTNDITQVQMLITMGLQVVTRGPIMAIWAIGKILGHSEYWLWAVLVAVIVNVLMTTV
                     LMTLDFPKQSLIQGLIDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIVFMSYAM"
     gene            complement(10016..10487)
                     /locus_tag="ACL8JK_001801"
                     /pseudo
     CDS             complement(10016..10487)
                     /locus_tag="ACL8JK_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            complement(10611..11327)
                     /locus_tag="ACL8JK_001802"
     CDS             complement(10611..11327)
                     /locus_tag="ACL8JK_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS1786633.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(12208..13623)
                     /gene="ply"
                     /locus_tag="ACL8JK_001803"
     CDS             complement(12208..13623)
                     /gene="ply"
                     /locus_tag="ACL8JK_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HGS1786634.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13634..14044)
                     /locus_tag="ACL8JK_001804"
     CDS             complement(13634..14044)
                     /locus_tag="ACL8JK_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786635.1"
                     /translation="MIKRGDVVALYLPFPTISSDLAVKNHMYICIDNSMTKNKELVKN
                     QTFKPALLTRRLVKNFMIEEPDLARNPFTRPTLIDLDKVFMLDNTVIPTSYLARRRRN
                     VSEELYEEILDHLVQPRLISLNKSEFMQLNPGTY"
     gene            complement(14037..14645)
                     /locus_tag="ACL8JK_001805"
     CDS             complement(14037..14645)
                     /locus_tag="ACL8JK_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786636.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14658..15116)
                     /locus_tag="ACL8JK_001806"
     CDS             complement(14658..15116)
                     /locus_tag="ACL8JK_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGS1786637.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            15241..15640
                     /locus_tag="ACL8JK_001807"
                     /pseudo
     CDS             15241..15640
                     /locus_tag="ACL8JK_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(16404..16664)
                     /locus_tag="ACL8JK_001808"
     CDS             complement(16404..16664)
                     /locus_tag="ACL8JK_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786638.1"
                     /translation="MRERSATGAQDLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
BASE COUNT         4918 a         3812 c         3000 g         4965 t
ORIGIN      
        1 gctttcaaat ttctaggctc aggctgaaac agtctcccag actgtttcac tcccgaatgc
       61 taaaatcgtt cttgatcgct ttcacattgt acaacatctt agccgtgcta tgagtcgtgt
      121 gcgtgttcaa attatgaacc aattggatcg aaaatcccat gaatacaagg ctatcaagcg
      181 ctactggaag ctcatacaac aggatagccg taaactgagt gataagcgat tttatcgtcc
      241 tacttttcgt atgcatttaa ccaataaaga gattttagac aagcttttga gctattcaca
      301 agacttgaaa catcactatc agctctatca actcttgctg tttcactttc agaataagga
      361 accggagaaa tttttcggac ttattgagga caatcttaag caagttcatc ctatttttca
      421 gactgtcttt aaaaccttcc tcaaagataa ggaaaagatt atcaacgccc ttcaactaca
      481 ctattctaac gccaaaccgg aagcgaccaa taatctcatc aaacttatca agcgcaatgc
      541 ctttggtttt cgaaactttg aaaacttcaa aaaacggatt tttatcgctt tgaacatcaa
      601 aaaagaaagg acgaaatttg tcctttctcg agcttagctg acttcaaccc actacagttg
      661 acaaagagcc tataaaaaga agggttagtc attccctcct tttgtgtttt ttataagttg
      721 ttttctatag aaagcttaca tcatcccgcc catcatgctt ggatccattg ctggagctgg
      781 ggctactggt tctggtttat tggctacgac tgcttctgtt gtcaaaatca agctggctac
      841 agatgctgca ttttgtaggg ctgaacgact cactttaact ggatcaatga taccttgatc
      901 aatcatgtta acccactcgc cagttgctgc gttgaatcct ataccaagct cagcattttt
      961 caaacgatcg ataacgatag atccttcaaa tcctgcattg tgagcaattt gacgaacagg
     1021 ttcttccaaa gcacggagaa caatattacg tcctgttact tcatctcctg tcaattccaa
     1081 ggtagcaaca gctggaatca cattggcaag agctgttcca ccacctgcaa caataccttc
     1141 ttcaacagct gcacgagtag cgttgagggc atcttcaatg cggagtttca tttctttcaa
     1201 ctcagtttca gttgcggctc cgaccttaat aaccgctaca ccacctgaca atttggccaa
     1261 gcgttcttgc aatttttcac ggtcaaattc agaagttgta gtttcgattt gagacttgat
     1321 aaccgcaaca cggtgagaaa tcgcttcagg atttcctgca ccttctacaa taaccgtgct
     1381 atctttgtcc acggtcactc tcgctgcttg accaagagct tcaattgtcg catctttcaa
     1441 ctcaagacca aggtcttctg tgataactgt tccgcctgtt aagatggcga tatcttcaag
     1501 catggctttg cgacggtcac caaaaccagg tgccttgact gctactacgt tgaaggttcc
     1561 acgaatcttg ttcaaaacaa gagttggaag agcctcacca tccacatcat ccgcaataat
     1621 caagagtgga cgattgcttt ggagaatgct ttccaaaagt ggcaagattt cttggatatt
     1681 ggaaattttc ttgtctgtaa tcaaaatgta cggattttca aggtcagcca ccattttttc
     1741 gctatctgtc accatgtact gtgaaaggta accacggtca aactgcattc cttctacgac
     1801 ttcaagctct gtttccatac cacgtgactc ttcgatggtg atgacaccgt ctttgccaac
     1861 tttttccatt gcttcagaga tgtactcacc aactttttca gaacgagaag atacggctgc
     1921 aacttgagcg atagcttctt tattggcaac agggatggcg ttgtttttca aagcttcaac
     1981 tgctgcggca actgctgttt caatcccacg acgaataccg attggatttg cacctgctgt
     2041 gacgtttttg attccttcac ggacgatagc ttgggtcaag actgttgcag tcgtagttcc
     2101 gtcacctgcg atatcattgg ttttagaagc tacttctgat actaacttag cacccatatt
     2161 ttcaaaatgg tcttccaatt cgatttcttt ggcaatggtc acaccgtcat tggtaatcaa
     2221 gggtgaaccg aatgactttt caagaacgac attgcgacct tttggtccca aggttacttt
     2281 aacagtgtct gcaaggatat cgacaccacg aaccatggct gaacgggcat ctgatgaaaa
     2341 tttaatttct tttgacatac ttactttctc cttctattcc tcaatgattg ccaaaatgtt
     2401 agcttcgcct acgatgatgt acttttcatc gccatctttg acatcaagac ctgcgtgggc
     2461 ttcaactaag acacgatctc cagttttaac acttggagca accaagtcac cgttcaaggt
     2521 acgaacacct tgtccagtag tcacaacttg agctgttttg gttttttctt gggctgagcc
     2581 tgcaaggaca aagcccccaa cggtttgttc tttttcttct atttttaaga gcacacggtc
     2641 ccctaatggt ttcaacatct gatttcctcc ataatgagat agatattatt agcactcttt
     2701 gaactggagt gctaattcat aattctattg tatcacttgg tcagaaatag tcaagaaaaa
     2761 agtctgactt tctcaagata aaaagcctga gaccaactca gactttttaa ttcttaaaat
     2821 ggcaattctt cctcttccaa gaccaaatct gccaaatctt ggcctgcatt attttcacgc
     2881 atagcacgtt gggcacgact ttccaagagt tggaatcctg tcacaaggac ttcggttaca
     2941 taattcatct gaccattttt ctcaaagcga cgggtacgca attctccatc aacggaaatg
     3001 agactacctt tggttgcgta gcttgccaaa gtttctgcta gtctgcccca tagaaccata
     3061 ttaacaaaat cagcttcacg ttcaccgttt tggtctttgt aacgacggtt gacagcgata
     3121 gttgctcgcg ctaccgactt gtcattgttg gttttgtgca attctggtgt agacgttaaa
     3181 cgcccaatca tgataacttt attatacata ttttcttcct cctacttatc tattcgtagg
     3241 aaatcaaaaa aagttacaga aatttgtaac ttttcgagga aatttcttat tttttatgaa
     3301 tcatgaaacc tgtcgcctgt tgattggcca taatggtcat atctgtaatc tgaacacggc
     3361 gaggctgact ggtcacatag actactgtgt ctgcaatatc ctgagcttgc aaggcttcta
     3421 ttccttggta aacggacgca gctcgttctt tatcaccatg aaaacgcact gtagaaaaat
     3481 ctgtttcgac aattccaggc tgaatggtcg tcaccttgat atccgttgcg atggtatcaa
     3541 ttcgcagtcc atctgaaaag gtcttaactg ccgccttggt ggctgagtaa acagctgcac
     3601 cagcataggc ataaattcct gcggttgacc ccatattgat aatatgacct tgattggctt
     3661 ttaccattgc tggcaagaaa cagcgagtga ctgccatcaa acctttgaca ttggtatcca
     3721 acatggtcag catatccaac tcttcatagt cttgataggg agctaagcca agagccagtc
     3781 ctgcgttatt gaccaggatg tcaatctgac ctatcgtttc taaaatatca gagcagacag
     3841 tctttactat tgtcatatcc gtgacatcta ggagaaaagt ccaaactgtt tgatttggaa
     3901 aagtttctgc aaactccgcc ttaagagctt ctagtctgtc tatccgtcgt cctgttagaa
     3961 cgacatcctc accctgctcc agataagcac gcgcaatcgc ttcaccgatt cctgaggttg
     4021 ctcccgtaat cactacattt tttgccatct tatttccttc tatcagatgc tgacaagttc
     4081 ctaggcagtc cagtgtttcg ctgggtcgaa cggtgttccg acaacttggt cttctgataa
     4141 ttcaagcacc ccacgttttt gcggagcatt tggcaaatgc aattcacgag gactacacat
     4201 catcccaaaa ctcttttcac cacgaagttc gcctgggaaa atgaaattcc cttttggcat
     4261 catggcacca ggaagagcca caatggtttt caacccaaca cgcgcattag gtgctcctgc
     4321 aacgatttgc actatcttgt cacttgcgac tgcaacttgg cagatgttga ggtggtcact
     4381 gtctggatga gctaccatct cgacaatttc accaacaaca aacttaggtt ccttatcatt
     4441 aacaatttct tctgtaaaac cttccgcctg taattcttgg ttcaaacgag cgacttgctc
     4501 atctgataaa aagacttgac cgcgctctgc aatttcaaac aagctcgaaa cctcaaaaat
     4561 gttccaagct actgtttccc cattttcttt gaggaaaaca cgggctacct tgcctttgcg
     4621 ttccatattc agtttggcat ctccgctatt tttcacgatg accataagga catcaccgac
     4681 atgttctttg ttatacgtaa aaatcattgt ttcctttttc tcctatttca atcctgctaa
     4741 aaaatcgtta atttgctcct tacttttacg gtcgcgattg acaaaacgac cgatttcctt
     4801 gtccttttct agaacaacaa ggctaggaat tccgtaaaca tcccagagtt tggccaaatc
     4861 catatactga tctcggtcca ttcgaataaa ggtgaactct ggattggtct cctcaatctc
     4921 tggtaaggca ggataaatat aacgacaatc gccacaccag tctgccacaa aaaggaagac
     4981 cttcttgccc gctttttcca ctaaagatgc taattcttct aaacttgctg gctgtatcat
     5041 aagacttcct cctcatagac taggtcttca ttttcataga caaaggtata atgacggcca
     5101 tcctcaaaaa tgacgccacc aaccaagctc tccagactgc tttcgtaaac ttgaacatag
     5161 aaggtcgcaa tttcccccat gtcggaaaaa tggtctcgca caatctctgt caactcttcc
     5221 tgagtcttca tgagcttacg gtcatctgca acttttttcg tggcaagagc aaggcttccg
     5281 atacctagca gagccaagcc tgccatccac atttttttag ctttcatacc attcatttta
     5341 acacaaaaaa ggcttcagga caaatgagga agcagcagaa aagcaagtaa aaagcctctt
     5401 cctttaagga aaaggacttc ttatactaag agcaaactag gaagctagcc gcaggctgct
     5461 caaaacacgg ttttgaggtt gtggataagg cgacgctgac gtggtttgaa gagattttca
     5521 aagagtatta ttcttattgc caggcgcctg agttgccaac gtagtaacca tcaggtgtgt
     5581 agatattgcg aagcatctta cctgatgaag ctagataata ccacttgcca ttgtctttga
     5641 cccaatcatt cgctagcatg gctccagaag aacttacata ataccattct cccttgtcat
     5701 aaacccaagt gcttgctttc atggctcctg agcaattaaa ggttcaaaaa actgtccaat
     5761 atcattcatt tttttaaagc attttacact acatcatcca cgctgtagga catagataca
     5821 tcaaatgtaa gagccaaaat atcgaaaaat atacaacttt taaaggcaac atttcatttt
     5881 ttaaagtcta acaaccatag aactgaaatc agagcaaggc atcaacttcc tactcttagt
     5941 acgtctattt tgatggttga agtgaagatt ttttatttaa cgtagacaat ttccaacttc
     6001 ccaaaagcca catctccacg gataatcaag gttttgctgg ttggggctac aggagcgtca
     6061 gccttagctg caccaaagga ggtttctact ttcaaatcta cacgccagtg ttgtggaaca
     6121 tagacggttg catttccgaa ggccacttca atatttaaag ttgcaaaatc acctagcatc
     6181 tctgcattat catagtagat tttagcatcc ccaaaagcga cttccacttg gtcatctacg
     6241 agatcttgat cttgcttata gaaggtcccg ctaccaaaag cgacttcctt atccgtgacg
     6301 actgtttttt tcccattgta ccaccatttt ttttcattcc agaacttact tgaatgcgtc
     6361 agataaccaa caccaagtac caccaagatg ctagcccaaa taagagaatg attggtaact
     6421 ggtaacaagt cataagcgta atttgcaatg atgagcgcca gtaaacctgt aaaaactgcc
     6481 gaagtgagat gacgtctaag gatggactca atggacttat aagcaaaaaa aacaatacct
     6541 agtaaaggcc atattttacc atccaaagaa ggaattccaa aattcccttg cagcaagatc
     6601 caagctgcta aaaccaataa aacaatacca aatgctttct ttttcatgtt ttttacctca
     6661 tgtttcttag attttctttt aggagggatt ggtaatgccg tgagacatga acctccttgt
     6721 gcgtctgata aaaggaaatg gtgcccgttc ctgaaaagga cttgtccact gagtaaatct
     6781 gacggatgtt tgcgatcgtt gacttggaaa ctcgattaaa atagcgaggc aagatagact
     6841 ccaactcata gagcttgagg cgaacctcat aagcttcctt ctggttatga gcgtagatct
     6901 tgctcccttc tgtttcaaag aagagaattt ctgacaggtc tagataatat tcacctgtcc
     6961 ccttgtaaaa agtcaacctc ggagcctttg actcttgcaa gagccgttgc aagtctgcaa
     7021 tttcatctgt caaagtgggg gtcttgatga caatttcagt ctcctctaaa ttgccgtcaa
     7081 tctcaattcg taacttcatc acatctcctt tctgactcta ctatatcaaa gctaagttag
     7141 gaatacaagg gcaaaaaagc aagtggtcaa tttgaagcag taagtggttg taggactagc
     7201 ttaacttaca tgtcagaata ggaagaaaag gaatccccac accaaaccac aagcatagcc
     7261 aaccaagaca tccttgggat aatgaacacc ccctaaaacc ctcaccaacc ccagcaaagc
     7321 tgaaaagatc aagcatacta agccaatagg tagactagca tgcagacagg ccatggagat
     7381 gatagttgcc gaaaagacat ggcgactggg catcgaccgt cccgaactat ccttatcaag
     7441 aaggggacag atatcccaag tttcataagg tctcgggtga ttgattttct tacgaaacag
     7501 ggacaaggcc acaaaacctg atgcaggaat aagcacataa accccaactt gctgaccaag
     7561 tcctagttgc aggtaagtgg tgactagcaa gatcagatag accaggggca tggcgactgt
     7621 catcaaacga ttgaaactgc gtaataggaa taaaagaatt ggacgactag ttagtctgga
     7681 gctgatattt cgataccatt cttgataatt tttcatttat gcttctcata cttttctaga
     7741 acttgttgag atgttttccc cttggcaagc caatccacta gcttgtccaa gcgacgtatt
     7801 tcctgcatca gaggatcatc aatttcctca atacggacac cgcaaatctt ccctgtaatt
     7861 gcaattcgtt cagggacata atatggtgct tgtctaaaaa aatctccgta agtaacatcc
     7921 ctatccagac aagcaagaac atcactcact tcataccctg tcaaccaact ggtcacttgg
     7981 tgaactgact ctgcctttcc accctttcgc tcaacttttg caatcaaggc taagtagaca
     8041 gcagcaaatt tcatattgta taatttctga ctcatacttc tctctttcta tgtgtactag
     8101 tataaataag aaaaagaagg ccgtcaagcc ttcttttgat ttattcttct gcttcatctt
     8161 ctgtaaattg actattgtac aagtcagcgt agaagccacc ttgcgccatc agttcctcat
     8221 agttgccttg ctcgatgata tttccatctt tcatgaccaa gatcaagtct gcatttcgga
     8281 tggttgacaa gcggtgggca atgacaaagg atgtgcgtca ttccatcaaa cggtccatgg
     8341 ctttttggat caattcctct gtccgtgtgt caacagaaga agtcgcctca tccaaaatca
     8401 aaagcggtgc atccttaaga agggcacgag caatagtcaa tagttgtttt tgtcctacag
     8461 acaaggtcac ggtgtcatcc aagatggtat catagccatc tggcaaggtc ataataaagt
     8521 ggtgaattcc cacagcctta ctagcttcca tcattcgttc atcactaatc cctatttgat
     8581 tatagatgag attgtctcga atagttcctt caaagagcca ggtatcctgc aagaccattg
     8641 aaaaggcatc atgcacttct gaacgcgtca tagccttggt atccacacca tcaatgcgaa
     8701 tacttccctt atcaatctca tagaatttca tcaaaagatt gacaatggtt gtcttaccag
     8761 ccccagtcgg cccaacaatg gcaacctttt gaccagcatg agctgtcgca gagaagtcat
     8821 agtcttgaac attgacaccg tccaccagaa tttctcctgc tgacacgtcg tagaaacgtg
     8881 gaatcagatt gaccagagtt gatttaccag aacctgttga cccaataaag gccactgttt
     8941 gaccagtttc tgctttaaag ctaacatgtt caataactgc ctccgaattt gccgcatagc
     9001 ggaaggtcac atccttaaac tcgacctgac ctttgaagtt ttcatcagtc agctgcactt
     9061 gaacagggtt ttggatagaa gaatgcaaat ctaaaacttg attaatccgc ttagcagaga
     9121 ccatagttcg gggaagaacg atgaagagtg ctcccatgag aaggaagccc atgacaacct
     9181 acatggcata agacatgaaa acaatcatgt cactaaagag aggcagacgc gctatcggag
     9241 cagcgtcgtt aatcacatag gccccaatcc agtaaatcgc tacactcaaa ccacttgaaa
     9301 tccccatcat gataggattc aaaatagcca taagacggtt gacaaacaaa ttcaaacggg
     9361 tcaattcatc atttactgct gcaaattttt cattttgata atcctctgca ttgtaggcac
     9421 gaacgacacg aatacctgtt aaactctcac gagtgatact gttcagttta tctatcagcc
     9481 cctgaatcaa ggactgtttt ggaaagtcta gcgtcatcaa aacggtcgtc atcaggacgt
     9541 tgacaatcac tgccacaagt acggcccaaa gccagtattc tgaatgacct aaaatcttcc
     9601 caatagccca aatagccata attggaccac gcgttaccac ttgcaagccc atagtaatca
     9661 acatttgaac ttgagtaatg tcattggtag tacgcgtcaa gaggctagga attgaaaatt
     9721 tcttaatctc tgtctgcgag taatccaaaa ctcggttaaa aatatcactt ctcagcctac
     9781 tagtataaga agccgccact cgggatgcaa aaaatccaac tgcaactacg gacaagaagg
     9841 caagaaagag cattcccatc atcatgcttg ccggctgcca caactcatct aaattagttc
     9901 cttgactacc tagcaaatcc gtaattttcg agatataggt cggcacttcc aactctagat
     9961 agaccgaaaa gcaagtaaag agaatggcta gtaaaatcat ccccattctt ttctactaat
    10021 tcttttggct aatttcttta ttctctcctc ctattccctt gatattttgc ctgtagttga
    10081 ccgagaactt tctcaaaaat cagtaattca tcttcatcaa tgtcttccat caactgcttg
    10141 tctatgcgtt caaaaaaagc cttaacctgt tgcatctgag aacgtgcttt gtccgtcaga
    10201 cgaacaaact tagcccgctt atcaacagga ctcgcctcca attccaccaa accattttgc
    10261 actatacgct taaccagatt actagcaaca gacttggtaa tattgagttc ctgctcgata
    10321 tctttaatca agaccaagtc ttggtttttc tcgcgattat ccaaaaaacg cacaacctga
    10381 ccttgcggcc cacccataaa ttcaatgccg caacgtttgg cttccttttg caccatcagg
    10441 taaatttgat gaccaaaacg cttaaagact aacatcggtt tatccataat ctcccccttc
    10501 taaataaaaa tagttctctg gagaataatt aaatttctat gagaactatt ttcttgatta
    10561 aaaaaatccc aagtgatttt ctcacttagg atcatgttct ataggttaaa ttaaaaccca
    10621 tctacgttcg tataaatctt ttggacgtct tcgtcgtctt caagaacgct gtaaagtttt
    10681 tcaaaggttt caaggtcttc gcctgacaat tccacttctg actgaggaat catttccaat
    10741 tcagtcactt ggaattcttc aataccagac tcacggagag caacgatagc cttgtgaagg
    10801 tcagttggcg ctgtgtaaac tgtgattgta ccttcttgtg cttctacgtc atccacatcc
    10861 acatccgctt cgagcaattg ctcaaagact gcgtccgcat cttcacctcc aaatacaata
    10921 acacctttgt tgtcaaaaag gtaagaaaca gaacctgaag cgcccatgtt tccgccgttt
    10981 ttaccaaagg ctgcacggac attggctgct gtacggttaa cgttagaagt caaagtatcc
    11041 acaattagca tagagccatt tggcccaaaa ccttcgtaac gtccttctgt aaaggtttcg
    11101 tctgtgtttc ctttggcttt atcaatcgct ttatcgataa tgtgttttgg cacttgggct
    11161 tgtttagcac ggtcgataac gaatttcaaa gctgagtttg attctggatc tggatcacct
    11221 tttttagctg ctacatagat ttctacacca aattttgcat atactttaga gttagctcca
    11281 tctttagccg ttttcttggc tacgatattg gcccatttac gtcccattag gaatctcctt
    11341 ttttcacatt ttaatctttc ttattataac acaagttttt ttgattttca ctagaggaaa
    11401 tggattttat tagcaaatca agctaggata gtactttacc tgctaagatg gtcttgcctt
    11461 tctatcttta tcaacagaca ctcatccaca ttcaaaaaac aaactagacc attatctgca
    11521 aatagaaagt ttcagccaag tttgacaaag tcagctcaaa ttactgtttg aagtttgtag
    11581 atataagcga caaaaacaat catactgcac cttttgttga cagtctactc cagacatatc
    11641 atagttccag taaatacttt gaaatccaac agttcttata ggcgctattg tattctaaga
    11701 aatcaataga agagtttcta agcaaacctc taatactcaa taaaaatcaa agagcaaact
    11761 agaaagctag cctcaggttg ctcaaaacac tgttttgagg ttgcggatag ggctgacatg
    11821 gtttgaagag attttcaaag agtataattt acgtgttccc aagatggaga agttagacta
    11881 gtacactggc acttctaaac cattgctagc aattgatttg ttcatattta atttcatttt
    11941 ttccataaat gggtattaga tataaacagc aaaatatttc cgatacgtgt cgttcttgaa
    12001 tttccaatca tctaaaacaa gtaaaggata atcaatcccc tgtatatcaa ggaattggct
    12061 acccttttta cttttttaca cattctgttt gatagattca ttttaacatc acgagcatac
    12121 tccaatggaa atcgctaggc aagagataaa ctttcagata tccgcagaga gatcatcgcc
    12181 tctttttgtc gcaagcattc tcctctccta gtcattttct accttatctt ctacctgagg
    12241 atagagagtt gttccccaaa tagaaatcgt ccgcttacgc actagtggca aatcggtttt
    12301 ttcataaacc gtacgccacc attcccaggc aagcccggta cactctctaa ttttgacaga
    12361 gagattacga acattccctt ttaaaggaat actagtggta aagtgagccg ttaaatcctg
    12421 cccatttctg tcccaagcct taggagtcaa gacttcctta ccttgatgat cataggataa
    12481 ttcattccaa gtaatataat attgggcaac ataggcacca ctatgatcca gcagtaaatc
    12541 tccgtttctg taagctgtaa ccttagtctc aacatagtct gtactatttt gaaaggtcgc
    12601 aactacattg tcacgtaaaa aagaagttgt ataggaaatc ggcaagcctg gatgatctgc
    12661 tgtaaagcga ctgccttctt gaatcaagtc ctctaccata tccaccttgc ctgttacaac
    12721 tcgggcaccc gaacttgggt cgccccctaa aataaccgcc ttcacttctg tattgtccaa
    12781 aatctgcttc cactctgtct gaggagctac cttgactcct tttatcaaag cttcaaaagc
    12841 agcctctact tcatcactct tactcgtggt ttccaacttg agatagactt ggcgcccata
    12901 agcaacactc gaaatataga ccaaaggacg ctctgcagaa attcctctct gttttaaatc
    12961 ctctaccgtt acagtatctt gaaacacatc tcctggattt ttaacagcgt ctacgctgac
    13021 tgtataataa atctgcttaa aattaacaat ctgaatctgc ttttcgcctg aatggacaga
    13081 gttaaaatca atatcaagag aattccctgt cttttcaaag tcagaaccaa acttgacctt
    13141 gagttgttcc atgctgtgag ccgtgatttt ttcatactgc attctagctg ggacattatt
    13201 gacctgacca taatcttgat gccacttagc caacaaatcg tttaccgctc cgcgaacact
    13261 tgaattgctg gggtcttcca cttggagaaa gctatcgcta cttgccaaac caggcaaatc
    13321 aatactataa gtcatcggag cacgatcgac cgcaagaaga gtgggattat tctctaacaa
    13381 ggtctcatcc actacgagaa gtgctccagg atagaggcga ctgtcgttgg tagctgttac
    13441 agaaatatca cttgtatttg tcgacaagct ccgcttcttt ctttcgataa caacaaactc
    13501 atcgggtagc tgattaccct ctttgatgaa acgattttca atactttctc cctgatgggt
    13561 caagagtttc tttttatcgt aattcatagc tagtataaag tcatttactg ctttatttgc
    13621 catcttctac ctcctaataa gttcctggat tgagttgcat aaactcagac ttgttcagcg
    13681 aaatcagccg tggttggact aagtgatcca aaatttcctc gtacaattct tctgagacat
    13741 tgcgtcgccg tctggctaga taagaagtcg gaataaccgt attatccaac ataaatacct
    13801 tatctaagtc aatcaaggtt ggtcttgtaa aaggattacg agctagatcc ggctcttcta
    13861 tcataaagtt cttgaccaaa cgtctggtca agagagctgg tttgaaggtc tgatttttaa
    13921 ccaactcttt gtttttagtc atgctgttgt caatacagat atacatatga ttcttcacag
    13981 ccaaatcgct actaatagtc ggaaaaggca aataaagagc tacaacatct cctctcttaa
    14041 tcaagcaaga gcaccccctt ttctcctaat gtaacataga caggattgac caagtcttct
    14101 gattgactca gaatttccaa agtttgagtt tggcgcgctg tcaatttagt agcatcttgt
    14161 ctcttcaata caaaatgctt gtcgccaata accttgacaa tataatcctt ctccaaagct
    14221 gactggtaaa tccacatcag atgttgtctg tcctgagaac tcaagagaga aggattttca
    14281 agcctcccga tagtctgata aaaatcaaaa acaggagcta actcctgcca atctgattgg
    14341 ctagttgtca aggctagaaa aagggctttg cgagctgata cttcttggtt agccttgaga
    14401 gttactttcc cctccaagtt ttttagaaat cgggaaactc cagaaagcaa atttttctct
    14461 aactgcgaga aataaaaacc tttcgttccc agacataagt ctttcatgtc gctttctcta
    14521 gcaaataaga gctcaaacat ttgatagtaa aagaaaaata tctggcactg ggtcgcgctc
    14581 atcttttcct tatcggcttc tttttttaac cagagcaagg gcgacaggta gctggattga
    14641 gacatttcct ctacctccta ctctttttta actggagcat ctgcactagc tgccacttct
    14701 tttgactgga tactttccca ctggttaatc tcctctgaga taagaccttc gcatgtcttg
    14761 acaaataggg caaaagcctt ggtctttcct gcatatttct ccgtttggca ttgatagagg
    14821 aatttttctt tctccaggag ttgcgcagtt ttttggtaag aaatccaatt ttcctttgca
    14881 ttatacaaat tgataatccc ctcacacagc aagccgagac tggataaggc aaccgaaatc
    14941 aaacggtagc gatcacctgg cataggaata gcacaaaaga cagctatgag gaaacctgcc
    15001 acgatttctg ttatttttaa taccttatag cgcctacgat gttgaacgct tttctttaaa
    15061 aaatgagcta tctgtacgtc taatcgctct gtcaggtaca tttcttctgg cgtcatattc
    15121 gtaactcctt tcatttactt tgataaccat agtataacat atttgaatat caaagtatag
    15181 taaaaactgg actataactt attagacttc ctgcgaaaca aaatatggta tagtagttct
    15241 atgaattatg aagcaagtaa acaactaact gatacacgat ttaagcgtct tgttggtgtt
    15301 cagcgtacca cttttgaaga gatgttagct gtattaaaaa cagcttatca aaaaagtcgg
    15361 acaagctggt aaaatcttgg ctgacagtaa ttatcaaggg ctcatgaaga tatatcctca
    15421 agcacaaact ccacgtaaat ccagcaaact caagccgcta atagctgaag ataaagccta
    15481 taaccgtgcg ctatctaagg agagaagcaa gattgagaac atctttgcca aagtaaaaac
    15541 gtttaaaata ttttcaacaa cctatcgaaa tcatcgtaaa cgcttcggat tacgaatgaa
    15601 tttgagtgct ggtattatca atcatgaact aggattctag ttttgcagga agtctattat
    15661 atatatgcac agacatatga aatctttttg atacagcctt ctttttacat agagagacag
    15721 cagttatgat atatttatcc atacacaaca tcttctgtac caatactaca atattggtac
    15781 attttgatta cacaatcgtt tcaaaaaata tgatggaagc ctgagtattt tatagtaatt
    15841 cccttcctat caactagatc aaccagttga gtgttgaatg ttgaaacacc ctagcctcag
    15901 caaaggacta tgatcagcat ttcctagcca ataggacgct ccaaatcacc tattctaagt
    15961 ccataactag cttggtcagt aagatacaga ctgcaaggcg agactgacgt ggttgatgag
    16021 atttttgaag agtattacaa tcatagattc accagtagac ttgaacgcag atttaactat
    16081 agtagattga aactagaata gtacacctct gcttctaaaa cattgttaga aatcgatttg
    16141 actgtcctga tcaatttgtc ctgttctcgt ttcattttac tatactaaaa aaccacctga
    16201 aacaaatcaa gtgactagag gataaaaaca aagactgggc aaaaagtttt gaaaagcaaa
    16261 aaacgcataa tatcaggtct tgaaaaacct tgatactata cgtttgattg tgggaagatt
    16321 gacttcattt tctcctgaaa ttgaagtttt ttctagtttc cagatataga cgaattcaat
    16381 atagccatct cgctacaatt attttaacca tcgagaaaat ttttcagaat ttcaaaaatt
    16441 tcattttgat ccaatgaaat gtcatcattt tgaagaatag ttgacttcac aggctctaat
    16501 tctatcacaa agcggtgcat gtctgctttt accgcactac ttgatgttat agccgataac
    16561 ttttcatctc ctagcaagga agctgtcaaa cgggtaaggt cattcaaatg ctttttaatg
    16621 gacttactta aatcttgagc acctgtagca gagcgctctc tcatatccag ccaagcttta
    16681 gccttaaaaa taatt
//
LOCUS       DBERXF010000047        15928 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.47, whole genome shotgun sequence.
ACCESSION   DBERXF010000047 DBERXF010000000
VERSION     DBERXF010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15928
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.47"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            822..1193
                     /locus_tag="ACL8JK_001809"
     CDS             822..1193
                     /locus_tag="ACL8JK_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HGS1786639.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
     gene            1201..1413
                     /locus_tag="ACL8JK_001810"
     CDS             1201..1413
                     /locus_tag="ACL8JK_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786640.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQTK"
     gene            1787..1912
                     /locus_tag="ACL8JK_001811"
     CDS             1787..1912
                     /locus_tag="ACL8JK_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786641.1"
                     /translation="MATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDGYLWA"
     gene            1893..2139
                     /locus_tag="ACL8JK_001812"
                     /pseudo
     CDS             1893..2139
                     /locus_tag="ACL8JK_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2296..3354
                     /locus_tag="ACL8JK_001813"
     CDS             2296..3354
                     /locus_tag="ACL8JK_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786642.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            3669..4646
                     /locus_tag="ACL8JK_001814"
     CDS             3669..4646
                     /locus_tag="ACL8JK_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786643.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGVAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            5023..5397
                     /locus_tag="ACL8JK_001815"
     CDS             5023..5397
                     /locus_tag="ACL8JK_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HGS1786644.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            5404..5586
                     /locus_tag="ACL8JK_001816"
     CDS             5404..5586
                     /locus_tag="ACL8JK_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786645.1"
                     /translation="MGIKMEKIFVIIFFVCLFISSITFLAYDFVSEEIKKLIIWMNVV
                     FLILIIAMIIYPKLRK"
     gene            5605..6507
                     /locus_tag="ACL8JK_001817"
     CDS             5605..6507
                     /locus_tag="ACL8JK_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786646.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHLLVSNLQLNLEIPLDFVVSTSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWSNKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            6563..6802
                     /locus_tag="ACL8JK_001818"
     CDS             6563..6802
                     /locus_tag="ACL8JK_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGS1786647.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAAAGVLATA
                     AGKIAYCIGYGVLNRGCDINGNPYPWDGFISATVR"
     gene            6799..7527
                     /locus_tag="ACL8JK_001819"
     CDS             6799..7527
                     /locus_tag="ACL8JK_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786648.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLISFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVANHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIVYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            8013..8204
                     /locus_tag="ACL8JK_001820"
     CDS             8013..8204
                     /locus_tag="ACL8JK_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786649.1"
                     /translation="MFFAGIGEIKLVGYLLYICVGLAPLFHIYVIGSELSFVKIVLSI
                     LGVIFVSMLTIARIYRTFL"
     gene            8663..8902
                     /locus_tag="ACL8JK_001821"
     CDS             8663..8902
                     /locus_tag="ACL8JK_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR4 domain-containing protein"
                     /protein_id="HGS1786650.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     GLHKITRDFASHTIPAIQAGVFILEDFRNILCTMM"
     gene            8887..9165
                     /locus_tag="ACL8JK_001822"
     CDS             8887..9165
                     /locus_tag="ACL8JK_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786651.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKLTSCCIVAKDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            9451..11619
                     /gene="pspA"
                     /locus_tag="ACL8JK_001823"
     CDS             9451..11619
                     /gene="pspA"
                     /locus_tag="ACL8JK_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HGS1786652.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPQVVEKSSLE
                     KKYEEAKAKADTAKKDYETAKKKAAEAQKKYEDDQKRTEEKGALEEETSRKVNDATLE
                     VQNAYVEYGEANKKKGKDREKKLADAQKKIDEAQEKLTKAKNEFQSVRAMVVPEPEQL
                     AETKKKAEEAKAEEAVAKEKSDKAAKEVEVAKKRVEAEEAELDKKVAELQNKVADLEK
                     EIADAEKTVADLEKEVAKLEKDVEDFKNSNGEQAEQYLAAAEKDLVAKKAELAEAKIK
                     AATKKAELEPELEKAEAELENLLSTLDPEGKTQDELDKEAAEAELNKKVEALQNQVAE
                     LEEELSKLEDNLKDAETNNVEDYIKEGLEEAIATKKAELEKTQKELDAALNELGPDGD
                     EEETPAPAPQPEKPAPAPAPKPEQPAPAPAPKPEQPAPAPAPKPEKTDDQQAEEDYAR
                     RSEEEYNRLPQQQPPKAEKPAPAPKPEQPVPAPKTGWKQENGMWYFYNTDGSMATGWL
                     QNNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWLQYNGSWYYLNSNGAMATG
                     WLQYNDSWYYLNANGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMA
                     TGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEASGA
                     MKASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNANGEWV"
     gene            12020..13141
                     /gene="mnmA"
                     /locus_tag="ACL8JK_001824"
     CDS             12020..13141
                     /gene="mnmA"
                     /locus_tag="ACL8JK_001824"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGS1786653.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKALSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTCDMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            13282..13737
                     /locus_tag="ACL8JK_001825"
     CDS             13282..13737
                     /locus_tag="ACL8JK_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS1786654.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAAVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            13747..15660
                     /gene="mnmG"
                     /locus_tag="ACL8JK_001826"
     CDS             13747..15660
                     /gene="mnmG"
                     /locus_tag="ACL8JK_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGS1786655.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
BASE COUNT         5194 a         2480 c         3255 g         4999 t
ORIGIN      
        1 aatagaattg tcattcgcaa gtcatataaa tgttgatagt ttttatagac ttctaagcgt
       61 tgcaagattt tctcggatta ttgacaaata aacggacatt ctgatagacg attgctctag
      121 cggcttagtg taaactttac aaatttggct tgtaattttt ttataaaatt cactttagtt
      181 acttgacagt tattatattt tcgctcataa tatagataaa aggatgggat aggagtttaa
      241 aaatttgaaa gcgctatcca taatcgtaac gcataatttt ctccttttcg tgaaaaaagt
      301 taacgtaatt ttgaaatgag cttaataaga ggtactatgt aggtagaaaa taaagatagg
      361 agaaaaagta tgaataaaaa aatattttgt attctagtat gtattatatc attgattagt
      421 ctagctatag tctttccatg gggctggtcg atataatgta agggagcttg agttgttagt
      481 ggaggataaa atgttaagag taatagtagt tattcaatct ttagtaataa tactgcttgc
      541 tgttgcttta ttattatctc ggaaaaactt tgattcgtta aatgttgttc ttataatgat
      601 gatcgtatca caattgttgt tattagtata tttgataaaa tcagggaatc agtgattagc
      661 tgttatttga attaagtaaa ctgttaagct tcaagcagta actggtttta aatatttaaa
      721 ataagataaa ggaaggaagt ctaatttagg taactaaaca aagcctgcga tcacttgtta
      781 ggaaaccatc ctaagcatgc ttaataaaaa ggagaaaaca aatggaactt gtattaccaa
      841 ataattatgt tgtgattgat gaagaagaga tgatgtacct tgatgggggg gctatatata
      901 tacccaggtg ggcaattaca ggagccatta ctggtgcagc atatgcagca ttagcagcag
      961 caggaggtgg aggccttcaa ctagttcttg catcttatgg attacgctcc gcactggtag
     1021 ctgggattgt taaaggttta ggagtattag gaattcatat tggaaatgct tttgcaaata
     1081 ctgttattag aagtattgca tctgctggaa ttggtgctgg agctgattgg atttttacca
     1141 atattattga tggctgggat gggcgacgtg ataatcaatt gagaataggt taataatctt
     1201 atgttgattg ttttaatttc agttattgtt gcattcctgt atcataaaat tacagagtat
     1261 gtcaacaaca ggaaaattga tattgttatt tttctatcat tgctgatttc tcattttatt
     1321 tggaattact attttttacc aattgaaata ttgatagcaa tcagtggagc aaatttacta
     1381 ttaagttttt taaaaaaatt acagactaaa taatattaat ctgtgtaata cagtagctcg
     1441 gtcattagat tctattgaag atataaatta aaaatgaggc tgggaaaaaa ctcaatttga
     1501 aaatgagatt gagtaaatct ttctatctat ataacgtata tcatcaatat ttttgaacac
     1561 ctgataatat gcatttttct tattttaaag attttttgcc tttcttcatt tcttgaatga
     1621 attggagaga tgactttatt taggtgtttg acattactat agataggatt tagcagtact
     1681 aatatgaact catattatag gtgcagactt aaattttgga agcaagctaa aggatatctt
     1741 atctaggtaa ctaagtgcta taacaagata tattggtgga gttagtatgg caactattac
     1801 taatgctctt aatattgcgg ctactgttgc tgaagtcttc tcattaggag gagccattgc
     1861 atatggttta gatatcgtag acggtaaatt tgatgggtat ttatgggcgt aaaactatag
     1921 ctatgaaaca ttttttttgc aggaattggt gaaattcatt ttttgttatt tttattatat
     1981 ctaagcatgt ctgctagtcc aattattgga ctagtgattg gatatactaa aataaatcta
     2041 ataaattcta ttattatagc tcttggtatg atattggcat taattttggt attatcaaga
     2101 gtgtatagaa aatattttta tagagacgat gatgactaaa gtttttatca ataatttggg
     2161 ctccttgtca actgtagtgg gttgaataaa agctaacgtc tggggaaggg tttaaagctt
     2221 tgctttatca aatattgact tacagagttg ctctattgta ttgatgtatt cttagtaaat
     2281 aatatggtgt tttaaatgaa agatgatcag aaatatttat tagcgggact ttattcgctt
     2341 ctagttgcaa tattttattt tccattgatt gagtccaagg ggatttttgt aagtatattg
     2401 atggcggttt tacttttata tttaatatac ttcattgcaa cagtcattca tattgtgata
     2461 attaagttta taagaaaaaa atcttttaag tatttggttc tatatccatt tacttacgat
     2521 gggagctgga gatttcaacc tataaactta ctctactttc cagaaatggt gagagatgtc
     2581 attccgatta atttagttca agaatattgc caaggacaac cttacggact gttaaaaaag
     2641 atgctgaaaa gaattcgatt gtcacgagag atatctttac tcctggctac cattatcgtc
     2701 tattttttta cgcatagaat tctacctctt tcagtattta cgttcatatt ttcttacata
     2761 ttgctatttg cacaatctta tttgggtggt aataccgctt ggattggaaa tagaagatta
     2821 ataatagatg atgaatttga aaaaatcttg ctttcaaaaa gttatataaa agaaatatca
     2881 tctgcacgat actcagaata cttgacatgt gaatacaaaa actttacacc aatcatattg
     2941 ttagctattt ttgaaaattt gcttgactcc tacttgcttc agaatcagag tgaggttgac
     3001 ttagatattt tttataaagt tttacctttg ctttataaag aaaaatatac tatgggattc
     3061 aattactttg taagtttaaa ttatttacta tataaggttg gatttttggg aatcatttac
     3121 gataatgaag cattaagaga tttgtcaaaa caatatttaa acaaaaatat ttcggaatta
     3181 caagatggtt ctttcgaggg cggtatacaa gatgctgttg cctctaaaca aatagtagtt
     3241 ataaatgaat ttatagcttg tttaaattcc agatgcatgc catcccaata tgatagattt
     3301 ttttataaag atagacctta tattttttcc agaaagagtc ctattaaggg gtgaaaattt
     3361 gttacatttg gattaacaag tgtcctaggg attagaaata actctagtat agctagatat
     3421 ttttgagtaa ctagaaatat cattaggcta ctcatatgat tgccagaaaa gatggctgat
     3481 gaatcttatt tatactgttg cagtaagcat tgtctaggat aaataagcta tcttgatggg
     3541 ggagattgga ataattttag tagaaacatt aaaggattat gggcaagtag cgcaggatta
     3601 ggtgatgcaa tgtgctaagt tggcttggtg ttagcagtag tattatttaa caatggaaag
     3661 tagactaaat gaaaaataaa cgttattttt ttgacacaat tttaatgatt ttactgctta
     3721 taagcacgat attttgtgtc agcccagtat ttataaaatt ggacatctta ggaactccct
     3781 ctcatgccat cttaaccttt gtattggcga taccgttatt ctatattttg tctcaatgct
     3841 tacatacttt gctattacta gtttcctcaa tcttttgtaa attaagacca atttattttt
     3901 attttatatt tgtgatcatt ataggagcta ggaaatacta tcgaattctc tttcaccaac
     3961 taatgggatt tagtccagga gtagcagtgt tttataagga gagtcaaaca actaagaatc
     4021 tgtttaaatt ttactacttc ttgtacttta caacactaat ttcatactat tttttcttta
     4081 cttttgtgta tgacaaaccg ttgcttttgc ctcttattcc attttctatt atcatagcat
     4141 tagtacaaaa actttataga attgagaatc agcaattatt tctgttaaaa tcaaaggtac
     4201 taacaatact ggaatctaag aagaattgtg agtttaatct tcaggattat catgaaattt
     4261 ggaaattgca atcaaaatct gagttgccat gcgtggcttt atcttatatc agtttaatca
     4321 agccatatct ttcagagagt gtgcgtgaac aaattgattt attagaagtt aagcgattta
     4381 aaaaaataaa tcatccaata tcactttatg gtatgttgga tgttataaaa ttaaatctat
     4441 atttacggca ttataatgaa aaaaataaat atgaatcaat gttaaagaaa attttagagg
     4501 taagaccaga ctttgtttta atcgagcaga atattgatga tagtttaaat agctcgcaac
     4561 cattatcttt atctttagcc atttcagaaa tccaactttt gcttgaagtg tatatgggga
     4621 tcaaacatgt ttcaattagg agataaaacc agaataatat ttgccattat aggggcaagt
     4681 tgcatattag tcagtatgta tcttattcca cttattaaaa ctgagaataa attttgggaa
     4741 atacttttat ttatattagg tgtattgcta attggaattg cgttactaag tcaaaaaaaa
     4801 taaattttga aatagtattg gtgagttcgc aatcatttat tgctagtggt ttagaactgt
     4861 taagtttcaa acaataattg attttaaacc ttaggtaacc tataaaaaca aataaggtag
     4921 agaaaggata tcttatctag gtagctaagt gataaaaaca cagtcgtcta tcacttgtta
     4981 ggaaactatc ctaactatgc ttaataaaaa aggagaaaat aaatggaact cgtattacca
     5041 aataattatg ttgctcttga gcaagaagag atgatgtatc ttgatggggg attttctatt
     5101 ctgagatggc ctgttgcaac agccattaat atagctttta atggtgtttt aggtggagga
     5161 gcaatcagtc tagttagaaa ttatattcgt aattatggtt tgcggcgagt tacaagcgca
     5221 attgctggag cagctgcaag atatgttggg gtacgagttg caaatagagt ggcaggattt
     5281 gcactgtctg ctattaatgg atttgcagct tggatgtcaa ttggcgatgc tattacaaca
     5341 atctgggcca acaatgatgt aaataggaga gacccaaatt taaacgcctt gtggtaacta
     5401 gatatgggta ttaaaatgga aaaaattttt gttattattt tttttgtatg tctatttata
     5461 tcatccataa cttttttagc ctatgatttt gttagcgaag aaataaaaaa attgattatt
     5521 tggatgaatg tcgttttttt gattttaatc atagcaatga taatttatcc aaaattaaga
     5581 aaatgataag gacactgtaa aattatgata cgtaaactaa tcattttttt attaatgctc
     5641 cctctttttg tcttgtggct agagttgcat ttgttagtga gtaacttgca attgaatcta
     5701 gaaattcccc ttgattttgt ggttagtacg agtcttgctt tctgtagttt gattttatca
     5761 aaaatagttt tagacatact atacgcattg aaagatttgt acaagaaaga agctcttatt
     5821 acgatttttc cttttatttt tataggcagg aagaaagtaa atgtgaggtt ctcgccctat
     5881 ttttcattcc atcgtaaaag tttgtcgcct gatgatttaa gatctaggat tatatggagt
     5941 tttattcttg aaattgctat tattctagta tttattttaa aaattccttt tgcaatcatc
     6001 atgcttacta caatattttt ctggactata atggatatca atcatctcgt ttttaataag
     6061 acggaatttc tttttaatca aaataaatgg gaaaaagaag attcgtttga aagcgatttg
     6121 acgaaaacgt taaaggacaa aatacaaaaa tcagagttaa gctattctga cttaatgtcc
     6181 cttcttctct atgatgcgat gaaccaatcc acctttttaa cggatagtga actttttgag
     6241 gatattttga aaaaaatcga agattctcat aacacccttc tgtgtacagg tcttgtcgag
     6301 ttactgctgt atgagatttc tattagtaac aataacaact ggtccaacaa ggttgataaa
     6361 attagaatac agctcatcag aatcaatcaa ttagattttt tctattatac aagttggtta
     6421 aggcaaaatt ttgatttctg tatgaataga gagtatcata aaatgaaatc tcggaaatta
     6481 ttactgagta ataaaaagat agtttaagtt cgtcctattt gtaaaacaaa tgaaacaatt
     6541 tcaactaagg aggagaaaac aaatggaact tgtattacca aataattatg ttgtgattga
     6601 tgaagaagta atgatgtatc ttgatggggg agcttattta agcaagcgtg cttgtcaagg
     6661 aatttgcgca gcagcaggtg tattggctac agcagcaggg aaaatagctt actgtattgg
     6721 atatggtgtt cttaatagag gttgtgatat taacgggaac ccttatcctt gggatggatt
     6781 catatctgca acagtaagat gagtaatgta gataagattc gaaaaataca catcatcgtg
     6841 tgttgggtgt atatattttt atcattcagg gcgattataa atgatacgga gtattttttg
     6901 cttatttttt tagcttttat ctactcaata gtatcactac ctctatattc tgtgaaaaat
     6961 aaaatagtat ctatctgtct agccataaat tcgattctgt taatcagttt ccccatttta
     7021 atcaataagt ttttcccaga aagttttttg acttataccg tattaataag tgtttttatt
     7081 acagagttga taatttttca tttaattggg aaagattttg atattaaatt gactaacgaa
     7141 tataagaaaa ttagtcagtt tagaagcaag gtgtctcaat ctccttggat aaaatattta
     7201 gagatttcta gttttatatt aactatattt ccatctattc tttatggtac agttgctaat
     7261 catgtactga ctcttatctt tttgataaaa atttgtgtag ataccacgat aaaattttta
     7321 ttcatcagat tatttgacac aagtacttta atgaagagga gaatattttt tcttttcgca
     7381 ttggatgtta tagtttactt atttttagga tatcttttag tgattcaaaa agcaggctat
     7441 ttgttttcgg ttttacttct tttttctaat ttttcagttc catttatcaa agaaaaggaa
     7501 tacgaattat ttaaaaatag caagtaatag aaatatggat taaatcttag aacggcttaa
     7561 aatcagatat gataaaggga aatagtctta tctaggtaac taagtgctac aaacacaatc
     7621 gaggatcact tgttaggatt acattttaat catgcttaat aagaatggag aattcctatg
     7681 gggattgtat tactctgaag tttcgaatac cttagttctc gtgattttga gctattctag
     7741 ctttagaatc cttcagaacg taaaatttta agcagtcaaa gacttagaat agcctgaaaa
     7801 catttatttt atagcaattc taggcttaga attgctcata tatatgtatt tgagctgctc
     7861 gatagttagg acagctctat tctgagaaat ctgagctatc aatgcttcag aatagtattt
     7921 cgccaatggt ttttattgaa gaggtgattg ttttatgata gtctaaaata aaactgattt
     7981 aatggagtaa atggagaatc gttacatgaa acattttttt tgcaggaatt ggtgagataa
     8041 aacttgttgg ctacttattg tatatatgtg taggactagc ccctcttttt catatatatg
     8101 tcataggttc ggaactgagt tttgtgaaaa tagtgttatc tattttggga gttatatttg
     8161 taagtatgtt aactattgct cgaatttatc ggacttttct ataaagaata gtttggactt
     8221 gaactgtatc taaaaacaga ggttggtcga ttatcagcct ctttcttgtc gttgaaaaga
     8281 gtgagatata ttgacttttg aaaaaaagat gtcataattg agttgggata aacctaaaag
     8341 taatatagta gattgaatct ggaatagtcc gttatgactg ttaaaatatt tctagaaatt
     8401 aatttgactt tcctaatcga tttgttcaca tcttgtttca atctactata ctttttcgtt
     8461 aaaccgttcg gcaattcatg gtgacatgga cacatagtag taagcacact atgtggcttg
     8521 gcagagctaa aaactgttcc cttgcgataa gcctaataag cacaacatag ggagttagag
     8581 aagccgactc taatcaacca ctttgggcag tagtgagaac tgccccgtgc ttttttattt
     8641 tgagaaaata tggagcttgt cgttgaaatt acttgattgt attttggatt atcaagaaag
     8701 attcaatgga aaaacatgtc aagtatcaac gaattataag tatttagaga ctttcaaagt
     8761 gaatttttgc ttgactgatt tacatcattt atttggttta cacaaaatca cacgagattt
     8821 tgctagtcat acgatacctg ctattcaagc tggtgttttt attttagaag attttagaaa
     8881 tatcctatgt acaatgatgt aatcgaaagg atatctttat atgagtttat cggcgatatc
     8941 ttctattcta agctaacaag ttgttgcatc gtagctaagg atttatctaa aaatactatg
     9001 aaattagacg tcatattttt tgaggataaa aataaaagat ccgcagtttt aggtttacga
     9061 agagacaaaa gcggagtgtt taaaccagtt actctacatt ttacaagcgc taagaaatat
     9121 gctaaagttc gtaaaacaga tgtgaaagaa atgaaatggc tataaagatt gtccgcagcc
     9181 ttaagcttgc gttttttgtt gtttaacgaa attaaaaaac aagctctctc atcggaaatg
     9241 tttttatagg aatgaaggaa gatgatgcta tgtttaaaaa gagaatcgaa aagggcaaaa
     9301 gtagtgtctt tatctttttg gagtagaagc ttatgatata gaaatttgta ataaaaatgt
     9361 aatataaaac atttgacaaa tatttacggg gggactatac ttaatataag tatagtctaa
     9421 aaatgactat cagaaaagag gtaaatttag atgaataaga aaaaaatgat tttaacaagt
     9481 ctagccagcg tcgctatctt aggggctggt tttgttacgt ctcagcctac ttttgtaaga
     9541 gcagaagaag ctccacaagt tgtcgaaaaa tcttcattag agaagaaata tgaggaagca
     9601 aaagcaaaag ctgatactgc caagaaagat tacgaaacgg ctaaaaagaa agcagcagaa
     9661 gctcagaaaa agtatgaaga tgatcagaag agaactgagg agaaaggcgc gctagaagaa
     9721 gaaacttcta ggaaggtaaa cgatgctact ttagaggtac aaaacgcata tgtagaatat
     9781 ggagaagcta ataagaaaaa aggtaaggac cgtgagaaaa aattagcaga tgcgcaaaaa
     9841 aaaatagatg aagcgcagga aaaactaacc aaagctaaaa atgagtttca atctgttcga
     9901 gcaatggtag ttcctgagcc agagcagttg gctgagacta agaaaaaagc agaagaagct
     9961 aaagcagaag aggcagtggc taaggaaaaa tctgataagg cagctaaaga ggtagaagta
    10021 gcgaaaaaaa gagtagaggc agaagaagct gagttggata aaaaagttgc tgaacttcaa
    10081 aataaagttg ctgatttaga aaaagaaata gctgatgctg aaaaaacggt agcagattta
    10141 gaaaaagaag ttgctaaact tgaaaaagat gtagaagatt tcaaaaactc aaacggtgag
    10201 caagctgaac aataccttgc tgcagctgaa aaagacttag ttgctaaaaa agctgaatta
    10261 gcagaagcta aaattaaagc tgctactaaa aaagctgaat tagaacctga attagaaaaa
    10321 gcagaagctg aacttgaaaa cctattatct acactagacc ctgaaggtaa gactcaggat
    10381 gaattagata aagaagctgc tgaagctgag ttgaataaaa aagttgaagc tcttcaaaac
    10441 caagttgctg aattagaaga agaactttca aaacttgaag ataatcttaa agatgctgaa
    10501 acaaacaacg ttgaagacta cattaaagaa ggtttagaag aagctatcgc gactaaaaaa
    10561 gctgaattgg aaaaaactca aaaagaatta gatgcagctc ttaatgagtt aggccctgat
    10621 ggagatgaag aagagactcc agcgccggct cctcaaccag aaaaaccagc tccagctcct
    10681 gcaccaaaac cagagcaacc agctccagct cctgcaccaa aaccagagca accagctcca
    10741 gctcctgcac caaaaccaga aaaaacagat gatcaacaag ctgaagaaga ctatgctcgt
    10801 agatcagaag aagaatataa ccgcttgccc caacagcaac cgccaaaagc agaaaaacca
    10861 gctccagcac caaaaccaga gcaaccagtt cctgcaccaa aaacaggttg gaaacaagaa
    10921 aacggtatgt ggtacttcta caatactgat ggttcaatgg ctacaggttg gctccaaaac
    10981 aacggttcat ggtactacct caacagcaat ggcgctatgg ctacaggttg gctccaatac
    11041 aatggttcat ggtattacct aaacgctaac ggcgctatgg ctacaggttg gctccaatac
    11101 aacggttcat ggtactacct caacagcaat ggtgctatgg ctacaggatg gctccaatac
    11161 aacgattcat ggtattacct aaacgctaac ggcgctatgg cgacaggatg gctccaatac
    11221 aacggttcat ggtactacct caacgctaac ggtgctatgg ctacaggttg ggctaaagtc
    11281 aacggttcat ggtactacct caacgctaat ggtgctatgg ctacaggatg gctccaatac
    11341 aacggttcat ggtactacct aaacgctaac ggtgctatgg ctacaggttg ggctaaagtc
    11401 aacggttcat ggtactacct aaacgctaac ggttcaatgg caacaggttg ggtgaaagat
    11461 ggagatacct ggtactatct tgaagcatca ggtgctatga aagcaagcca atggttcaaa
    11521 gtatcagata aatggtacta tgtcaatggt ttaggtgccc ttgcagtcaa cacaactgta
    11581 gatggctata aagtcaatgc caatggtgaa tgggtttaag ccgattaaat taaatcatgt
    11641 taagaacatt tgacatttta attttgaaac aaagataagg ttcgattgaa tagatttatg
    11701 ttcgtattct ttaggtacct atcttatgat ttcaggaaat gtcattaaaa aaacgactcc
    11761 ttttctctaa cttgaaaaat agattagaga aaatgggttg ttttatttat tatagttatt
    11821 tgaatgaaga taagaagaag gtatactcac atcattcaca tcatctgtat gttgactata
    11881 agttttaaaa aacaattttt aagctcttcc ttgtcttctc caaccaagcg tgttataatg
    11941 aatactgctc aagcgacctt caatcgtgaa gcacacacga ccttcaatcg tgaataaacg
    12001 aatagatggg agacttacca tgagtgataa ctctaaaaca cgtgttgtcg tggggatgag
    12061 tggtggtgtt gattcgtcgg tgacggctct tttgctcaag gagcagggct acgatgtgat
    12121 cggtatcttc atgaagaact gggatgacac agatgaaaac ggcgtctgta cggcgaccga
    12181 agattacaag gatgtggttg cggtggcaga ccagattggc attccctact actctgtcaa
    12241 ttttgaaaaa gagtactggg accgcgtttt tgagtatttc ctagcggaat accgtgcagg
    12301 gcgcacgcca aatccggacg ttatgtgcaa caaggaaatc aagttcaagg cctttttgga
    12361 ctatgccata accttggggg cagactatgt agcgactggg cattatgctc gagtggcgcg
    12421 tgatgaggat ggtaccgttc acatgcttcg tggcgtggac aatggcaagg atcagaccta
    12481 tttcctcagc caactttcgc aagaacaact tcaaaaaacc atgttcccac taggacattt
    12541 ggaaaagcct gaagttcgaa aactagcaga agaagcaggt ctttcgactg ctaagaagaa
    12601 agactcgaca gggatttgct ttatcggaga aaagaacttt aaaaactttc tcagcaacta
    12661 cctgccagct cagcctggtc gcatgatgac tgtggatggt cgcgatatgg gcgagcatgc
    12721 aggtctgatg tactatacga ttggtcagcg tggcgggctt ggtatcggtg ggcaacacgg
    12781 tggtgacaat gccccttggt tcgttgtcgg aaaagctcta agcaagaata ttctctatgt
    12841 aggacaagga ttctaccatg attcgctcat gtcaaccagc ctagaggcta gccaagtcca
    12901 ctttacttgt gatatgcccg aggagtttac gctagaatgt acggctaaat tccgttaccg
    12961 tcagcctgac tctaaggtga ccgtccatgt caaaggagac aaggcagagg tcatctttgc
    13021 ggaaccacaa cgcgccatta caccaggaca ggcagttgtc ttttacgatg gcgaagagtg
    13081 tctaggtggc ggtttgattg acaatgctta ccgcgatgga caagtttgtc agtacattta
    13141 gattgacaaa ttttctcaat ttgctacaat aataacagca atagaaatga tggtcaaagc
    13201 tcatggatgt tgcaggcttt tttgtcctgc acttctttgt agttttgact gtttttgtgt
    13261 cgtttaaggg aaaggacaag aatgactcaa caagactttc ggacaaaagt agacaatacg
    13321 gtttttggtg ttcgggcgac agccttgatt gtccaaaatc acaagcttct agttaccaaa
    13381 gacaagggca agtattacac tattggaggt gcgattcaag tcaatgaaag cacggaagac
    13441 gcggcagtcc gtgaagtgaa ggaagaactg ggtgtcaaag ctcaagctgg gcagctagct
    13501 tttgtggttg aaaatcgttt tgaagtggac ggcgtttcct atcacaatat cgagtttcat
    13561 tatctggtgg atttgcttga agatgccccg ttgaccatgc aggaagatga gaaaaggcag
    13621 ccctgtgagt ggattgactt ggataagctt gaggatatcc agctagttcc agccttttta
    13681 aaaacggccc taccagattg ggaaggccaa ctaagacaca ttcatcttga ggaataggag
    13741 agaaacatga cttatcattt tactgaagaa tacgatatta ttgtaattgg tgcgggacac
    13801 gctggggttg aggcttcctt ggccgctagc cgtatgggct gtaaggtcct gcttgcgacc
    13861 atcaatattg aaatgctggc tttcatgcct tgtaatccct ctatcggtgg ttctgccaag
    13921 gggattgtcg tgcgtgaagt cgatgccctc ggtggcgaga tggccaaaac cattgacaag
    13981 acttacatcc agatgaagat gctaaacaca gggaaggggc cagctgtccg tgcccttcgt
    14041 gcgcaggctg acaaggaact ttactctaag gagatgcgca agacggttga aaaccaagaa
    14101 aatctgaccc ttcgtcaaac catgattgat gagattttgg tggaagatgg caaggttgtc
    14161 ggtgtgcgta cagccaccca tcaagaatat gctgctaagg ctgttattgt gacgacaggg
    14221 actgctctcc gtggggaaat tatcatcgga gacctcaagt actcatcagg tcctaaccac
    14281 agcttggctt ctattaacct agctgataat ctcaaggaat taggactcga aatcggtcgt
    14341 ttcaagacag gaacccctcc acgtgtcaag gcttcttcta tcaactacga cgtgacagaa
    14401 attcagccag gagacgaagt gcctaatcat ttctcataca cttcacgtga tgaggattat
    14461 gtcaaagatc aagtgccatg ctggttgacc tacaccaatg gtaccagtca tgagattatc
    14521 caaaacaacc tccaccgtgc gcctatgttt acaggtgtgg tcaagggagt ggggcctcgt
    14581 tactgtccgt cgattgaaga caagattgtg cgctttgcgg acaaggaacg tcaccaactc
    14641 ttccttgagc cagaagggcg caatactgag gaagtctatg ttcaaggact ttcaaccagt
    14701 ctgcctgagg atgtccagcg tgacttggtt cattccatca aaggtttgga aaatgcagag
    14761 atgatgcgga caggttatgc tattgagtat gatatggtct tgcctcatca gttgcgtgcg
    14821 actctggaaa ccaagaaaat ctcaggtctc ttcactgctg gtcagacaaa tggaacgtca
    14881 ggttacgaag aggcagcagg ccaagggatt atcgcgggta tcaatgcggc tctgaaaatc
    14941 caaggtaagc ctgagttgat tttgaagcga agtgacggtt atatcggggt catgatcgac
    15001 gacttggtga ccaagggaac cattgaacct taccgtctct tgaccagtcg tgctgaatat
    15061 cgtctcattc ttcgccatga caatgctgat atgcgcttga ctgagatggg acgcgagatt
    15121 ggccttgtgg atgatgaacg ctgggctcgt tttgaaatca agaaaaatca atttgataat
    15181 gagatgaaac gcctagacag tatcaaactc aagccagtca aggaaaccaa tgctaaggtt
    15241 gaggaaatgg gcttcaagcc gttgacagat gcggtgacag ccaaggaatt ccttcgccgt
    15301 ccagaagttt cttaccaaga tgtggtggcc ttcatcggac cagctgcaga agacttggat
    15361 gacaagatta tcgaattgat tgaaacagaa atcaagtatg aaggctatat ttccaaagcc
    15421 atggaccagg ttgccaagat gaaacgcatg gaagaaaaac gcattccggc caatatcgac
    15481 tgggatgaca ttgattctat cgcaaccgaa gcccgtcaga agttcaaact catcaatcca
    15541 gaaaccatcg gccaagccag ccgtatttcg ggagtaaacc cagcagatat ttctattttg
    15601 atggtgtatc tggaaggtaa aaatcgtagt atttctaaaa ctcttcaaaa atcaaaatga
    15661 tacgtcgtag gcttcttacg aatgagttca aagcttggct ttgattcatc tccaacctcc
    15721 catagttccc cgaactatgg gagctaactc aagttatgca ttttcctagc cttctggtct
    15781 gattttcatt gagttttaat ctaaaaagaa agcatagaga aaaacagctc cgaagacggg
    15841 gctgttttgt tgatttgtac tcaatgaaaa tcaaagagca aactaggaag ctagccgtag
    15901 gttgctcaaa gcactgcttt gaggttgt
//
LOCUS       DBERXF010000048        13553 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.48, whole genome shotgun sequence.
ACCESSION   DBERXF010000048 DBERXF010000000
VERSION     DBERXF010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13553
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.48"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            76..1335
                     /locus_tag="ACL8JK_001827"
                     /pseudo
     CDS             76..1335
                     /locus_tag="ACL8JK_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
     misc_feature    1411..1546
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1585..2085
                     /gene="rplJ"
                     /locus_tag="ACL8JK_001828"
     CDS             1585..2085
                     /gene="rplJ"
                     /locus_tag="ACL8JK_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGS1786656.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2161..2529
                     /gene="rplL"
                     /locus_tag="ACL8JK_001829"
     CDS             2161..2529
                     /gene="rplL"
                     /locus_tag="ACL8JK_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGS1786657.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            2716..2886
                     /locus_tag="ACL8JK_001830"
     CDS             2716..2886
                     /locus_tag="ACL8JK_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786658.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2886..3134
                     /locus_tag="ACL8JK_001831"
                     /pseudo
     CDS             2886..3134
                     /locus_tag="ACL8JK_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3148..3488
                     /locus_tag="ACL8JK_001832"
                     /pseudo
     CDS             3148..3488
                     /locus_tag="ACL8JK_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134542.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3481..3861
                     /locus_tag="ACL8JK_001833"
     CDS             3481..3861
                     /locus_tag="ACL8JK_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGS1786659.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3874..4107
                     /locus_tag="ACL8JK_001834"
                     /pseudo
     CDS             3874..4107
                     /locus_tag="ACL8JK_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            4110..4697
                     /locus_tag="ACL8JK_001835"
     CDS             4110..4697
                     /locus_tag="ACL8JK_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS1786660.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            4899..5036
                     /locus_tag="ACL8JK_001836"
     CDS             4899..5036
                     /locus_tag="ACL8JK_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGS1786661.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            5215..7824
                     /locus_tag="ACL8JK_001837"
     CDS             5215..7824
                     /locus_tag="ACL8JK_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGS1786662.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            7857..9797
                     /locus_tag="ACL8JK_001838"
     CDS             7857..9797
                     /locus_tag="ACL8JK_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HGS1786663.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            9794..11401
                     /locus_tag="ACL8JK_001839"
     CDS             9794..11401
                     /locus_tag="ACL8JK_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1786664.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKSQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            11416..12156
                     /locus_tag="ACL8JK_001840"
     CDS             11416..12156
                     /locus_tag="ACL8JK_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1786665.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            12159..13478
                     /locus_tag="ACL8JK_001841"
     CDS             12159..13478
                     /locus_tag="ACL8JK_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786666.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
BASE COUNT         4536 a         1897 c         2662 g         4458 t
ORIGIN      
        1 aaccacacct acggcaaagt gaatctgaag tggtttgaag agagtacaac ttgtctttta
       61 gaaaaggagc ctacaatgaa agtctttcag catgtaaata tcgtgacttg tgatcaaaat
      121 ttccatgttt atcttgatgg aatcttagca gtcaaggatt cttaaatcgt ctatgtcggt
      181 caagataagc cagcgttttt agaacaagct gagcagatta tagactatca gggagcttgg
      241 attatgcctg gtttggtcaa ttgtcacacc cattctgcaa tgacaggtct gagagggatc
      301 cgagatgaca gcaatctcca tgaatggctc aatgactata tctggccagc agaatctgag
      361 tttactcccg acatgactac caatgcggtc aaagaagcct tgacagagat gctccagtca
      421 ggaacaacaa cctttaacga tatgtataat cccagtggtg tggatatcca gcaaatttat
      481 caggtggtga aaacttccaa gatgcgttgt tatttttctc cgactctctt ttcttcagag
      541 acagaaacaa ctgctgagac tataagcaga actcgatcca tcatagatga aatcttaaaa
      601 tataaaaatc caaatttcaa ggttatggta gcacctcatt ctccgtatag ctgcagtaga
      661 gacttgctgg aagcgagttt ggaaatggca aaagagctaa atattccgct ccatgtccat
      721 gtggcggaga ccaaggagga gtcaggaatt atcctcaaac gatacggcaa acgccccctt
      781 gcttttcttg aagaactggg ttatttagat catccgtccg tatttgctca cggggtcgaa
      841 ttaaacgaga gagaaattga acgcttggca tcttctcaag tggctatcgc ccacaatcct
      901 atcagtaacc tcaaactggc atcaggaatt gctccaatta tccagctcca aaaagcggga
      961 gtagcagtcg gaattgcgac tgactcggtt gcttccaata acaatctaga tatgtttgag
     1021 gaaggaagga ctgcagctct tcttcagaag atgaaaagtg gggatgccag ccagtttcca
     1081 atcgaaacag ctctcaaggt actgacaatc gaaggggcta aggtccttgg aatggaaaat
     1141 cagataggaa gtctggaagt cggcaagcaa gcagattttc tggtcattca accacaaggg
     1201 aaaattcatc tccaacctca ggaaaatatg ctgtctcacc tggtttatgc agttaaatct
     1261 agtgatgtag atgatgttta tatcgccgga gaacaggttg ttaagcaagg tcaagtcctg
     1321 acagtagaac tttaaaagaa aaattacgaa aaattttaaa aaaagtttgc aaaaatcttg
     1381 cattcttttt ttgactatgc tatacttata tacggtttaa aaaaactgcc taagacagta
     1441 ggggagctcg actcataaat atcctaccga ggacaaaacg tatcatgtaa aaagaagcgt
     1501 attgtacttt cgtgtctagg tttgggcgcg tttttctttt tgaaaaattc cccaagcaaa
     1561 ataattacgg aggtgaacac actaatgagt gaagcaatta ttgctaaaaa agcggaacta
     1621 gttgacgtag tagctgaaaa aatgaaagct gctgcatcta tcgtcgttgt agacgctcgt
     1681 ggtttgacag ttgagcaaga tacagttctt cgtcgtgagc ttcgtggaag cgaagttgag
     1741 tataaagtta ttaaaaactc aatcttgcgt cgtgcagctg aaaaagctgg tcttgaagat
     1801 cttgcatctg tatttgttgg accatctgca gtagcatttt ctaatgaaga tgttatcgca
     1861 ccagcgaaaa tcttgaacga cttttctaaa aacgctgaag cacttgaaat taaaggtggt
     1921 gcaatcgaag gcgctgtcgc atctaaagaa gagattcttg cacttgcaac tcttccaaac
     1981 cgcgaaggac ttctttctat gctcctttct gtacttcaag cgccagtgcg caacgttgct
     2041 cttgcagtca aagcggttgc agaaagcaaa gaagacgcgg cttaatctta agctacacag
     2101 cgtagcctag ctacgaaaaa aactattata aaatttaaaa cttatttgga ggaaataaca
     2161 atggcattga acattgaaaa cattattgct gaaattaaag aagcttcaat ccttgaattg
     2221 aacgaccttg taaaagctat cgaagaagaa tttggtgtaa ctgcagctgc tcctgtagct
     2281 gttgctgcag ctgatgcagc tgatgctggt gctgctaaag attcattcga cgttgaattg
     2341 acatctgcag gcgacaaaaa agttggcgtt atcaaagttg tacgtgaaat cactggtctt
     2401 ggtcttaaag aagctaaaga acttgttgac ggtgcaccag cacttgttaa agaaggcgtt
     2461 gcaactgcag aagctgaaga aatcaaagct aaattggaag aagctggagc ttcagttact
     2521 cttaaataat agagtatcgc aatttgattg cggaatccct atttaccagt ctttgagagc
     2581 gataagcgat tgatagaaac tgataaattg atttggtttc ctgccaaaaa ttctttggca
     2641 ggatttttgt tttaataaac tttcgggggt agacactaga ttgtctaccc ctttttttgt
     2701 gtttcggagg taattatgca aaaggaagga cagtcatcac gtcaattcgt gaagagtcat
     2761 ctcatgacta tcatgggagt tgatattgta aaagcaactc agttagttga tgaaatggaa
     2821 caagtaggtt taatccgatt tgatgaattt ggaaatgttg gaattttagt cttggaggga
     2881 caataatgaa gcgtattacc gctaatcaat atcagacatc agagcgttat tataagctcc
     2941 ccaaactttt atttgagagt gaacggtata agaatatgaa actggaggtt aaggtggttt
     3001 actcagtttt aaaagatcgg ttggagttgt ctttgagcaa aggttggatt gatgaggatg
     3061 gggctattta tttgatttat tccaattcaa atttgatggc acttttaggc tgttcaaagt
     3121 caaaattact ctccatgtga gtttgaagtg acatttttag atgattacca taaaaaacat
     3181 aactacccac tattttacga atcctatctt caaaacgtta tggaattcct tgaaagtcaa
     3241 gacataaaga atggggttga tgcctttgta gatgatcatc aaaatctcgt ttttgtttta
     3301 tatggacaag gctatcgagc cgagggaaaa gagggaatac ttacaaccca agtaactgta
     3361 aaagcttatg atgaagacaa gaaaccgatt aacttcgcaa atttattaga ttccttaatt
     3421 tattagattc cttaatcgtg tcagaatatc aaatggaacc gaatctttgg gaggtctccc
     3481 atgattgatc tctatctaag taaaaataga caaagaaatc aacttctttt agatttcttc
     3541 caaaactatg gcatagaggt atcttgtcat tcagtttctg aaatgacaaa ggacaaatta
     3601 attgagatga tgagctattc ttcagattgt tttgagtttt tatctcccaa tttattacga
     3661 tttaagaacc gtgacaatct aagattaacg gatttcgttg agataatttt aaaaaatcct
     3721 gaactaacca tcagacttcc tcttgcggtt tcaaataagc gagtttatcc aagtctgaat
     3781 ttggaagagg ctagagctct attgccaaga gatacgaaac aattgattta catggcgcaa
     3841 acacattatt tatctaacta aaggagaagc aatatggctg aacgattttg ggagaacttg
     3901 tccattattt tggctgaaag aaatatcagc tggattgagt taaccagaaa aatgtttgcg
     3961 ggagagtttc actatccaag tgaattgaat cgtttgtatc aaaagattcg ccactagaag
     4021 atggaacaat gaatgcctca aagtccatgg gtagaaagga ttgtgcaggt attagattta
     4081 gattatgaag atttatttcg gaggtaacta tgaaaagaat aattccagtt tatatattcc
     4141 aacaagtaaa tgtcctattg gtatctctat acttattgaa atttctttgt atcggtgagt
     4201 taactatact acagattctc tatggttcgt cactcatttc ttttttatgg atgtatggcc
     4261 aacgcaaaca agcgcataag gtcaatatga aatctaggat gaaatggctt ggtgttgaat
     4321 ttgttagcct actgattata agtctatgtt ttagtctgat tcatgctcaa ggaagcacga
     4381 atcaagcaaa cttaattggc cttcaacatc aaattccttg gttttcattt ttattgttct
     4441 taatcaatgc gagtatggtt gaagaatttc tgtatcgaga aattttatgg aatttggtca
     4501 gaaaattaga tatcagagtt gctttgacaa gtgttttatt tgccttagca catcatacag
     4561 gaaccattct agcttggtgt ttgtatgttt cacttgggat gtttttaggt atggtgcgct
     4621 ataaatctga cttatggggc agtatgggac tacatttggt gtggaaccta ctagtttata
     4681 gtttgctgct tttttaaaat aggtgacctg atttttaggt aacttctaaa actaacttcc
     4741 agttttggga gagagatgga agttactttg aaaagttacg gaaacattat tttctatgtg
     4801 acaacattgt ataattgctt gcattttact ggtggagaga gtataatgag ggtggataaa
     4861 gtacttaatc ccaaaaattt aaataggagg agctagctat ggcagaagaa gtattaaatc
     4921 ttcaattagt atctgttcaa gttgacgaaa cagatgaagt tgatggaatg cgatttagta
     4981 cattcagtac aaatcgttgc ggtaactgga gtgcttttag ttgggaaaat tgttaattca
     5041 tttaaattgt aaactttaga gattctctgg agttatggat gtcgttccaa tatgtgcacg
     5101 ttggaatgtt agtgcttata tggggagaat ccaaaggatt ctcccttttt atttaaataa
     5161 gtctgtctag ctatagatat attaagtttg ataaaatttc ttggagattt tgttatggat
     5221 tataatttca atttggagca tcctttcttt ttcactaata atgattatag tacagatact
     5281 agcataaagt accaagtaag tctgcctttt aattggcacg aagtaatgaa taatgatgag
     5341 tgggtttatc aataccctat tggaaaattt gttgaaagac aagggtggaa aatacacatt
     5401 agttcagagt ataacagttc acatgaattg ttacaagatg tagcaaaaat ttgccatgaa
     5461 atgcgaattc catttaaaca tcttagtaca gaagacaaat ttatcatgcg aaacgggaaa
     5521 ttggttagtc gaggattttc tggtaaattt attacatgtt atccaaatca aaatgaatta
     5581 gagtcggttt tgcaaaggtt agaaagtgcc ttaaagcaat ataatgggcc atatatttta
     5641 agcgataaac gttgggatga agcaccaata tatctgaggt atggtgtgtt taggccgtca
     5701 agggatgatg aaaagaaggt tgctattgat gaattaattg ttggcgatga agttgttaaa
     5761 gatgaacgtt taccagtatt taaaattcca aaaggtatag tgccccctga ctttttgaat
     5821 aaatggcttg acaagaaaga taaaaaacag ggagactttc cctttattat agataatgca
     5881 attagatttt caaacagtgg tgggatatat aatgctaggc taaaagaaga tgggaaaaaa
     5941 ataattttaa aagaggctag accgtataca ggtctaggat ttgatggtac ttattcttca
     6001 gagaaattag cttcggagtg caaagcacta aaaattctaa atgaatggag tgagacgcct
     6061 aaaatatact ggcacggtaa gatctgggag cacaccttct taggaattga acatatgaag
     6121 ggcgttccac taaatagatg ggttaccaat aattttcctt tatatgaagt tgttgataag
     6181 accaaagatt atctattgag agtttcaaag atagtagaaa aactcatcga tttaacgaat
     6241 aagtttcatt ctgaaaatgt atatcatcaa gatttacatt taggaaatat cttggttaag
     6301 gatgaagatg agattagtat aatagactgg gaacaggctg tcttttcaaa tgatgaaaaa
     6361 gttgtacata aagttgcagc ccctggtttt agagcatggc gagaaacact tcccagtgag
     6421 atagattggt atggtattag acaaatagct cattatttat acatgccact agtaactaca
     6481 tcggatttga catacaacta tgtaagtcaa accaggatag aaggaaaaaa actatttgag
     6541 tctttgggtt atacaagaga acatatagat tatgtagaaa gtttattgtc atatctagat
     6601 tctaaatgtc cacagattga gaatatttcc aggaaaaaag ttttaaaacc catgcatgag
     6661 attagaacta tcgagagtga gcaagatata caagatttta ttataaaatt attgagaggg
     6721 tttacgctaa cttatggaca gtggcgtaaa gaatttcaat caagattctt cccagttcat
     6781 tattatggtc tgaattttaa tcaaggaatt gcgttttcag atttagctat cctttggagt
     6841 tatcaacaac tagctaagaa agtaaaaaat ttcaagtttg atgactatta tgagattcga
     6901 acacaggtta ttaatgaggc agtaaataat tttaagaaat cgtccctttc tggtcttttt
     6961 gatggtaaaa ttggtacaat ctggctcatt tatgaatttg gggagataga tcgggcagtt
     7021 gaacttttta caactcattt tatagagata tttgagaatt cacaaaataa aaatttatat
     7081 agtgggcagg ctggaatttt actggttgga ctgtattttc ttagtaaagg ggaaattgat
     7141 aataaactag gagaagaaat actaattagg cttagagaat atactttaaa ttatatagaa
     7201 aatccagaaa ctttttgtaa agttggcgct agtgatgttc agagtaatga tccttatgag
     7261 aattttggtg gattactata tggtcacgca ggggtagctt ggctcttcgg tgaagcttat
     7321 aaattaactg gtgaaagtat ctataaaaat ggtctagaat tggctgtaga taaagaatta
     7381 gttgcttata aagtagatag taataattca ttgcagtaca gccaaggtca tagattacta
     7441 ccatatctag caactggaag tgctggcctg cttttactta ttaatagaaa taaagaaatc
     7501 ttgtcaagca aatacttaaa atatttaact tctttagaga gggcaactga tgtagttttt
     7561 tgtgtattac caggtttatt taacggattt tgtggtcttg aagttgctaa taatatatat
     7621 agtgatatcg atgataactt ttcaggacaa aagaaattaa ttgaacaact ttatagatat
     7681 ttgtgtgtaa ttgaagaagg atttgttatt gcgggagata atggtttaaa gataacaaca
     7741 gatattgctt cgggatttgc gggtgttgca attggattgg tatcaataat ggataataaa
     7801 ttgacgattc ttcctcaaat ataatattta gataccatta ttaaggggtc atacttgtga
     7861 atcagagtaa tgaaatattt ttaaatacaa tacaggaaaa aacacactat aagaggtcta
     7921 tctcttcatc atttcaggaa ttaaaaaaat ggaattcttt gatatttagg agagggcgat
     7981 attggtacca atttgataat tggagtatac ccaatactgg tgtaataaag gaatggtatg
     8041 tcgaagataa tgactggatt cctaaggtta gttcttccag tttagacaat tcaaattcac
     8101 ttaaaattgt ctttgatgtg gaaaaatata ctttgccaga tgatagtatc ttacaggatg
     8161 ttaggatttc atctgatgag agttatatag ttttggttgt atcctcactg cgtagcacta
     8221 atttaattgg aataaaaaaa tatactatgg aagagttatt tatcattgaa gatatttcag
     8281 tagaaagttc gttctatttg ggtaaattcg gtgttatgta tactcgctcc aaagagtacg
     8341 ggaggccaag taagttattc tataaatctt ttgatagctt tacagaagag gaactgtttg
     8401 aagaaaacga atgctctttt cgattaaaaa tagtccacat tgatagcaat aattgttttg
     8461 taaagtcagt agactttcag aaaggcagga tttttctata cagtttcgac cggacgggtt
     8521 ttgttagaca ctcttacaca gaaacggtag ccccaacacc tagagatatc gctctattta
     8581 gtacagaaaa agcacagtac tttcttgggc tctcttcaac tgaagaaaag aaagatcaac
     8641 taattctaag ggaaacttct tcgggagaca gagtttctat tactatacca tatcaagata
     8701 gggctagaag agttcactgt ataggacgtt atatcctttt agactgttca aacgcagcga
     8761 attccgtctt ttatcttgct acatttaaaa ataatagttt gagggagttg agtgttaata
     8821 agataacatt tgatgaaaag acaacacttt atgaaaattc attttctgat cgtgttcttc
     8881 tgtttttaga gaggagaact ttttacgaaa aaatacttag ttttgattta atagaaaata
     8941 cattaaaaac tgaatttgaa agacccatca taaaatcgaa taatactaaa tatttttcta
     9001 aggtgatttg gactaaaaaa gacagttatg atgtaagcat accgatttct ttattttgga
     9061 aaagtgaaga tacggatgag ctcccaagaa gaaaaaaatg tattctaagt gtctatgggg
     9121 cttatggtaa gaatgataat tctgatttag atgaaattat gttatctata atagatgcag
     9181 gttttattta tgctatagtt catgtaagag gtggaggcta tttgggtggt gaatggtatc
     9241 gctcaggaaa ggcgttaaac aaatggaatt ctatcagaga ttttattgag ggagtaaatt
     9301 atttaaggga aaatgatgta attgacagta agcgattagg tttaataact tctagtgcag
     9361 gtggaataat tgctggtgcg gtgttgaacg aggaaaaaaa tttattgcaa agcattctct
     9421 tattttcgcc atttataaat ccttatgata cacttcagaa tccaaatgat cctctttcta
     9481 agaccgaaat agcagagtgg ggagatatta gagaccctga agtaaaggct tatataaagt
     9541 catattcgcc tatgcaaaat attgaaaagg cacgagactc aaatactgtt atagttaata
     9601 ttttgggtga gaaagaccca tatattaata ataacgaagt gatagagtgg tcaaagaaat
     9661 taaattctat tggagttaaa agtttgttgt atttaaacaa agcagctggt catggaggtt
     9721 ttactccatc agatgttctc ttaatgattg atactttaaa ttatttcttt gaagaagtgg
     9781 gaaggaataa cttatgaatt atttaaaatt tataaaaaag actaaactta tattaatggg
     9841 gattttaata tttctatctt cgtttaatgg tgtcttgctc tcaggaatta ttgtatatgc
     9901 aggtagttta aatcagactt cctcattttc tgacgttcta agatttggtg ctataagtat
     9961 tctgggttgg tcagcaatct atatatcaaa ttactattta gaagtaacgg aagcatcaat
    10021 aacgaaagat ataaatgtaa aaattaaaca aggatatttt agagaacagt atctttcttc
    10081 tgaaatggtt aaagattact catctattat ttcagttttg tcaaatgatt tgagattaat
    10141 cgaagaaaac tattttagac aaatttttga aataatttct tcaatattgt tgttcatcgt
    10201 ctctctaagt tttatgcttt atttaaactt cctagtttca ataatattta ttgtattatc
    10261 agcattgccg attatagtac ctgtctttat gaagaagatg ttgtctaatt cagctaatga
    10321 gtactctaac agcaatgcag agtatactca cataataaaa gaaattttta atggttttaa
    10381 gacattaaaa tcttattctg ttactaaaga aataattagt ttgtcggata aaaagttgga
    10441 taaactagaa gattctactt ttaatttgaa acgatcagag gttctttcaa aattggttgc
    10501 agtactaatt tcaggttttt gctttctagt tcccttggtt gtaggatgtt attttgtaat
    10561 ttatcataaa agcctttctt ttagtgaact gataggtatt ttcttagcaa acgataaagt
    10621 tttagggccg atacaatcaa ttgcctattc attaaataag ataaatacaa ccaaagattt
    10681 aaggaaaccg tttttaaaat acttaagtgg agagaagaat tttatagacg ctgaacatga
    10741 taataacgga ctgtatactt catcaataga tgagatacac atgaaagatg ttgtatattc
    10801 tattacacca gaaaataaat taagtattga cttctcattt aagtcaccat ttagggtatt
    10861 attaacagga acttctggta gtgggaaaac aacgatttta aatttaatta atggttcttt
    10921 aaagtcacaa aaaggttatg taaatttgtt atcacatggg aaaaagagtt cagattcaat
    10981 accaacagtt gatcagacac catatatttt tgacactact attcgtgaga acgtaacttt
    11041 atttcaaaat gaatattttt cagatgatca gataattgag gtgttaaaaa aggtaaatct
    11101 atatgaagaa ttagaaaaga tagatatact aaattatcaa tgtggtgaaa atggtagtaa
    11161 tttgtctgga ggtcaaaaac aaaaaatagc tttagctaga gctctgatta gaaataataa
    11221 agtgtactta tttgacgaaa tatcagctaa tttagataat gataattcaa attccataca
    11281 tgatattctg ttcaatttag gtatttcatt tattgaagtt tcacatcatt atgacttaaa
    11341 tgacaagaga tacactgata tatataaatt ggaaaatgga acacttttca aaattaagtg
    11401 attggaggca agaatatgga taaagattat atattaaaag tgaaagggct gtatcatcaa
    11461 tttttactag gaaataataa aacgttgcaa gtgctgaaaa atgtttctct ttctgcttcg
    11521 agaggagaat ttataagtat tctaggaatt agtggttctg gaaagtcaac tttattaaaa
    11581 tgtatttcta gtttgcttga accaacaagt ggggaagtaa ttttaaatgg aatcaacccc
    11641 tataaaatca gaaatgcaaa attgtcaagt ataagacgta acgaagtatc ttttatattt
    11701 caagcataca atttaatacc ttccctgccg gtaatagaaa atatagcact tcctttgcga
    11761 ttatcacaaa aaaaattaac tattaaaaat gtagaaaact tactcaaaag aatgaagttt
    11821 aatgctggct taaacgattt tgttggaact ctgtctggtg gagaacaaca gaaggttgct
    11881 atagctagag cggttattgc tgatagtgat ataatatttg ctgatgagcc aactggggct
    11941 ttagacagcg tttctcgtga agtaattttt gaattattga gagagttagt aggggcgggt
    12001 aagtgtgtaa ttatggtaac gcacgatata gaattggcct cgaaaactga tcgtgcatta
    12061 atattgaaag atggaaaaat tttcaaagaa cttcatagac ctagcgggga agagttgtat
    12121 aaaatcttag aggtacaatc aactacggag gaatagagat gctcagatta gtttactatc
    12181 aatttttaca taataagaaa caatggttag gcgtttcacc agtaattttt gtttcgagtt
    12241 tagttatggg attggctgtt aatggggtaa ttaatgttga gaataattcg caagtatttg
    12301 tcggacttcc agatcctaaa ccaattttta tgtttccgat agtattcgga ggagtaacat
    12361 tattctttgt gctctctaac ataataaata tgttggttga aatttttaga gatgattacg
    12421 aacttctgga ggtgttggga gcaagtctcc ttcaactatc atttcttgtg gggggacaga
    12481 tttttatcat ttcctcgatt attagtttta ttgcatatct atgctctata tttgttacgt
    12541 caaattatta ttatttttta caatactttt tcggggaaaa tatattacct gatatccaat
    12601 ttcaaacgag tgctgttgga tgtatcatta cagtagtgtt gatttcattt ttagcctttc
    12661 taagtggttg cttttatacg ttcaagaaga ttagaaatag gaagagttct aaaataaggc
    12721 atgttctttc aatagtaaaa agaatactgc tattggctgg ttttagtgtt atctggttgc
    12781 tttctttgca acaaattttc caagatagca caattttagc gaaggcccag ataatattca
    12841 atattgtaat cttagatatt gtgattattt atcaattatc tccttttata cagtcatgtt
    12901 ttatcaaact actttctata attatattta gaaataattt tatgttcatt gtttcgaagt
    12961 ggaatttact atatcgtaag ccttatataa aatctatcag tgctgcaatt acaggagcta
    13021 tattactaat ttctagtttt caaatgattt ctcagaatat actatctcaa tttcaagatg
    13081 acagtgattt agagctaaaa gtggcattta ttgtctatgt aggagcacca attttgatag
    13141 tacttgcaaa tattatttca attgcatttt tgtcatcgca tcaagaaagg attgagattc
    13201 agcaatttga aattttagga acttctaatt accagatggt taagattaaa gttggtgagg
    13261 ctatattttt gacatttgtt acttcattaa ttgcattttt acttaacatt aaaattatgg
    13321 ctttaatata ctactcttta gaggatattt taatagatga tatgaatctt ttggggttaa
    13381 tacttccaaa ttttatagtg tctattattt tatttatttt aatatttatt actaaaagtt
    13441 cctattttat ctttaagaat gcaaaaatta tttcttaaaa atttgtaagt tttcgctata
    13501 taaaatagtt aaatctattt tgtatcattg cttgcatttt actggtggag aga
//
LOCUS       DBERXF010000049        13403 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.49, whole genome shotgun sequence.
ACCESSION   DBERXF010000049 DBERXF010000000
VERSION     DBERXF010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13403
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.49"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            148..804
                     /locus_tag="ACL8JK_001842"
     CDS             148..804
                     /locus_tag="ACL8JK_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGS1786667.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            794..1117
                     /locus_tag="ACL8JK_001843"
     CDS             794..1117
                     /locus_tag="ACL8JK_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HGS1786668.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1221..2051
                     /locus_tag="ACL8JK_001844"
     CDS             1221..2051
                     /locus_tag="ACL8JK_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1786669.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2205..3059
                     /locus_tag="ACL8JK_001845"
     CDS             2205..3059
                     /locus_tag="ACL8JK_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGS1786670.1"
                     /translation="MKIKKWLGLVALATVAGLALAACGNSEKKADNAITIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3159..4532
                     /locus_tag="ACL8JK_001846"
     CDS             3159..4532
                     /locus_tag="ACL8JK_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGS1786671.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4525..5586
                     /locus_tag="ACL8JK_001847"
     CDS             4525..5586
                     /locus_tag="ACL8JK_001847"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGS1786672.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5588..6280
                     /locus_tag="ACL8JK_001848"
     CDS             5588..6280
                     /locus_tag="ACL8JK_001848"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGS1786673.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6310..6879)
                     /locus_tag="ACL8JK_001849"
     CDS             complement(6310..6879)
                     /locus_tag="ACL8JK_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGS1786674.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVTPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7014..7628
                     /locus_tag="ACL8JK_001850"
     CDS             7014..7628
                     /locus_tag="ACL8JK_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGS1786675.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7606..9276
                     /locus_tag="ACL8JK_001851"
     CDS             7606..9276
                     /locus_tag="ACL8JK_001851"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS1786676.1"
                     /translation="MKNWRQNRMKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSR
                     EKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQ
                     LERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDF
                     KPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIF
                     HMGETVDKESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLT
                     LRQTFANYQKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNI
                     HDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLR
                     NNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVE
                     NYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQ
                     ASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9288..10574
                     /locus_tag="ACL8JK_001852"
     CDS             9288..10574
                     /locus_tag="ACL8JK_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS1786677.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10626..11159
                     /locus_tag="ACL8JK_001853"
     CDS             10626..11159
                     /locus_tag="ACL8JK_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1786678.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            11237..11707
                     /gene="nrdI"
                     /locus_tag="ACL8JK_001854"
     CDS             11237..11707
                     /gene="nrdI"
                     /locus_tag="ACL8JK_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGS1786679.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12000..13262)
                     /locus_tag="ACL8JK_001855"
     CDS             complement(12000..13262)
                     /locus_tag="ACL8JK_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HGS1786680.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT         3924 a         2513 c         3084 g         3882 t
ORIGIN      
        1 tcagttctat ctgcaacctc aaaacagtgt tttgagcaac ctgcggctag tttcctagtt
       61 tgctctttga ttttcattga gtattattaa gacaatatga ggagaaagat gaaagaaaaa
      121 ggattttagg agggggcgca ggcagccatg ccaacggctc ttggctatgt cagtatcggc
      181 ctggcctgtg ggactatcgg tgcgccctat gtgacacctg ttgagatggg cttgatgagt
      241 ctctttgttt atgctgggag tgcccagttt gccatgttgg cactgattgt ggttcaagct
      301 cctgtggcag ctattgctat gacggttttt ctaatcaact tgcgtctctt tttgttgagt
      361 ttacacgcat cgacttattt ccgtcatacc agtctttggt acaatatcgg tatgtctagt
      421 atcttgacag atgagaccta tggcgttttg atgggtgaat tggcccatac agacaaggta
      481 aatcctatgt ggatgcacgg aaacaatctt aacagctatg tggcttggtt tgtggggaca
      541 gtagtcggaa cggctctggg tggcctgcta ccaaatccag aaatctttgg cttggatttt
      601 gccctggttg ggatgtttat tggtattttt gcttcgcaat ttcagattat gcaaagacgg
      661 attcctgtcc gcaatctgct cattatccta gcagttgttg cggtgtcctt ctttttgctc
      721 ttgacagtgg tgtctcagtc actagctgtt ctgtttgcga cgctacttgg ttgtagcatg
      781 ggggtggttt tagatggtca gtaagtatct tttattagca gttattttct ctggcttggt
      841 gacttggatt ctccgtatga ttcccttcat cttagtcaag tataagggct tgcctgcaat
      901 cgttgagcgt tttttgaagt tcttgcccgt ttccattatc tttgccttga ttctttcaag
      961 cgtagtgaca ggtaaggttg ggagccttcc tcaaattaaa tggctagact tcttagccgt
     1021 ctttccaaca gcttgggtag cctttcgcta ccgcaatcta gtcggaacag ttctctttgg
     1081 agtggtcttg attgccatct tgcgtttggt cttttaaatt acccataaaa aaaacttatc
     1141 acagagatag atatcatata atggcgtaaa tgctcttttt ctgttaagat tataaggtat
     1201 tctattttgg aggaaatgac atgaaaaaaa tcgttaaata ctcatctctt gctgccctag
     1261 gacttgttgc tgcaggtgtg cttgcggctt gctcaggggg tgctaagaaa gaaggagaag
     1321 cagctagcaa gaaagaaatc atcgttgcaa ccaatggatc accaaggcca tttatctatg
     1381 aagaaaatgg cgaattgact ggttacgaga ttgaagtcgt tcgcgctatc tttaaagatt
     1441 ctgacaaata tgatgtcaag tttgaaaaga cagaatggtc aggtgtcttt gctggtcttg
     1501 acgctgaccg ttacaatatg gctgtcaaca atcttagcta cactaaagaa cgtgcggaga
     1561 aatacctcta tgccgcacca attgcccaaa atcctaatgt ccttgtcgtg aagaaagatg
     1621 actctagtat caagtctctc gatgatatcg gtggaaaatc gacggaagtc gttcaagcca
     1681 ctacatcagc taagcagtta gaagcataca acgctgaaca cacggacaac ccaactatcc
     1741 ttaactatac taaggcagat ttccaacaaa tcatggtacg tttgagcgat ggacaatttg
     1801 actataagat ttttgataaa ataggtgttg aaacagttat caagaaccaa ggtttggaca
     1861 acttgaaagt tatcgaactt ccaagcgacc aacaaccgta cgtttaccca cttcttgctc
     1921 aaggtcaaga tgagttgaaa tcatttgtag acaaacgcat taaagaactc tacaaagacg
     1981 gaacgcttga aaaattgtct aaacaattct tcggagatac ttatctacca gcagaggctg
     2041 atattaaata atttcttgaa atcatccatt ctgagtaaga tgggtgattt ctcagttttt
     2101 agggatatag ttttaaacta tatatctgat tatctaataa caatttgtga aatcaaacaa
     2161 attgtgagat actagtacgg tattattttt aaggagaaag aatcatgaaa atcaaaaaat
     2221 ggcttggcct agtagccctt gctacagtcg caggtttggc tcttgcagct tgcggaaact
     2281 cagaaaagaa agcagacaat gcaataacta tcaaaatcgc aactgttaac cgtagcggtt
     2341 ctgaagaaaa acgttgggac aaaatccaag aattggttaa aaaagacgga attaccttgg
     2401 aatttacaga gttcacagac tactcacaac caaacaaagc aactgctgat ggcgaagtag
     2461 atttgaacgc tttccaacac tataacttct tgaacaactg gaacaaagaa aacggaaaag
     2521 accttgtagc gattgcagat acttacatct ctccaatccg cctttactca ggtttgaatg
     2581 gaagtgccaa caagtacact aaagtagaag acatcccagc aaacggagaa atcgctgtac
     2641 cgaatgacgc tacaaacgaa agccgtgcgc tttacttgct tcaatcagct ggcttgatta
     2701 aattggatgt ttctggaact gctcttgcaa cagttgccaa catcaaagaa aatccaaaga
     2761 acttgaaaat cactgaattg gacgctagcc aaacagctcg ttcattgtca tcagttgacg
     2821 ctgccgttgt aaacaatacc ttcgttacag aagcaaaatt ggactacaag aaagcacttt
     2881 tcaaagaaca agctgatgaa aactcaaaac aatggtacaa catcattgtt gcgaaaaaag
     2941 attgggaaac atcacctaag gctgatgcta tcaagaaagt aatcgcagct taccacacag
     3001 atgacgtgaa aaaagttatc gaagaatcat cagacggttt ggatcaacca gtttggtaat
     3061 aagaaacagg gaggtgggag agagaattcc acctcttgct tttgtataga gcacggagtg
     3121 taaagaagac tattcgttca tagaaaggta gagagaatat ggtttttcct agcgaacaag
     3181 aacagattga aaaatttgaa aaggatcatg tagcccagca ttattttgag gttttgcgta
     3241 ccttgatttc taagaaatca gtctttgccc agcaggttgg actcaaggaa gtcgcaaatt
     3301 atctgggtga gattttcaag cgtgttggag ctgaagtgga gattgatgag agctatacag
     3361 cgccctttgt catggcacat ttcaagagtt cgcgtccaga tgccaagacc ttgattttct
     3421 ataaccacta tgacactgtg ccagcggatg gggatcaggt ctggacagag gatcctttta
     3481 cgctttcggt ccgcaatggc ttcatgtatg ggcgtggagt tgatgacgac aagggtcata
     3541 tcacagctcg cttgagtgct ttgagaaaat atatgcagca ccatgatgat ttacctgtca
     3601 atatcagctt tatcatggag ggagcggagg aatcggcttc aacagaccta gataagtatt
     3661 tggaaaagca tgcagacaaa ctccgtgggg cggatttgtt ggtctgggaa caagggacca
     3721 aaaatgcctt ggaacagctg gaaatttctg gtggcaataa ggggattgtg acctttgatg
     3781 ccaaggtaaa aagcgctgat gtggatatcc actcgagtta tggtggtgtt gtggaatcag
     3841 ctccttggta tctcctccaa gccttacagt ctcttcgtgc tgcggatggc cgtatcttgg
     3901 ttgaaggctt gtacgaagaa gtacaagagc ccaatgaacg agaaatggcc ttgctagaaa
     3961 cttatggtca acgaaaccca gaggaagtta gtcggattta tggattggag ttgcctctct
     4021 tacaggagga gcggatggcc tttctaaaac gtttcttttt cgagccagcg cttaatatcg
     4081 aaggaatcca gtctggttat caaggtcagg gtgttaagac tattttacct gcagaagcca
     4141 gtgccaagct agaggttcgt ctggttccgg gcctagaacc gcatgatgtt ctggaaaaaa
     4201 ttcggaaaca gctagacaaa aatggctttg ataaggtaga attatactat accttgggag
     4261 agatgagcta tcgaagcgat atgagcgcac cagccattct caatgtgatc gagttggcca
     4321 agaaattcta tccacagggc gtttcagtct tgccgacgac agcggggaca ggacctatgc
     4381 atacggtctt tgatgcccta gaggtaccaa tggttgcatt cggtctagga aatgccaata
     4441 gccgagacca cggtggagat gaaaatgtgc gaatcgctga ttattacacc catatcgaat
     4501 tagtagagga gctgattaga agctatgagt agagatatta tcaagttaga tcagatcgat
     4561 gtgacttttc accaaaagaa gagaaccatt acagcggtta aggatgtgac cattcacatc
     4621 caagaagggg atatctacgg aatcgttgga tattctggag cagggaaatc aacccttgta
     4681 cgggtgatta acctcttgca aaaaccatct gcagggaaaa ttaccattga cgacgatgtg
     4741 atttttgacg gcaaggtgac cttgacggca gagcagttgc gtcgtaaacg tcaagatatc
     4801 ggaatgattt tccagcattt taacctgatg agccaaaaga cagcagagga gaatgtagcc
     4861 tttgccctta aacactctga actcagcaag gaagaaaaga aggctaaagt agctaagttg
     4921 ttggacttgg ttggtttggc agatcgtgct gaaaactacc cttcacaact atctggaggg
     4981 caaaaacagc gtgtggcaat tgcgcgtgcc ttggccaatg atccaaaaat cttgatttca
     5041 gacgagtcaa cttctgccct tgatccgaag acaaccaagc agattttggc cttgttgcaa
     5101 gatttgaacc aaaaattagg cttgactgtt gtcttgatta cgcatgaaat gcagattgtc
     5161 aaagacattg ccaaccgtgt tgcagttatg caggatgggc atttgattga agagggtagt
     5221 gtgcttgaaa tcttctcaaa ccctaaacaa cctttgactc aagactttat ctcaacagct
     5281 acaggtattg acgaagccat ggtcaaaatc gagaagcaag aaatcgtgga acacttgtct
     5341 gaaaacagtc tcttggtgca actcaagtac gctggagctt caacagacga gccacttttg
     5401 aatgaattgt acaagcatta ccaagtaatg gctaatattc tctatgggaa tatcgaaatt
     5461 ctcgatggta ctcctgttgg agaattggtg gtggttttgt caggtgaaaa agcagcgttg
     5521 gcaggtgccc aagaagccat tcgtcaagca ggtgtacaac taaaagtatt gaagggagta
     5581 cagtaagatg gaatcattga ttcaaaccta tttaccaaat gtctataaga tgggttgggc
     5641 tggtcaggca ggctggggaa cggctatcta cttaactctt tatatgacag ttctttcctt
     5701 cattatcgga ggcttcttgg ggctagtggc aggtctcttt ctcgtcttga cagcgccagg
     5761 tggtgtcttg gagaataaag tcgtattctg gattttagac aaaattacct caatttttcg
     5821 tgcggttccc tttatcatcc tcttggcaat cttgtcacca ctttctcact tgattgttaa
     5881 aacaagtatc gggccaaatg cagcccttgt cccactttct tttgcagtct ttgccttctt
     5941 tgcccgtcag gtgcaggttg tcttggctga attggatggc ggtgtcattg aggcggctca
     6001 agcgagcgga gcgactttct gggacatcgt gggtgtttac ctatcagaag gtcttccaga
     6061 tttgatccgt gtgacgactg tgaccttgat ttcccttgtt ggggaaacag ctatggccgg
     6121 tgcggttgga gctggtggta tcggtaacgt agccatcgct tatggattta accgctacaa
     6181 tcacgatgtg accatcttgg caaccatcat tatcattttg attatctttg caatccaatt
     6241 cttgggagat ttcttgacta agaaattgag ccataaataa aaaagagccg tgtggctctt
     6301 tttaactgat cagattttct gggcaaattt tttactcaag gcttgtccaa tcaaggcacc
     6361 cactagggct ccgatgacaa tacttgcgat aaatagaagg acagttccag ggtttggagt
     6421 gaccatgata cggtcgatat attcttggga ttttcctctt gccagaagag tagccatata
     6481 ggctttgggc gcaatccaca taagcaagat tggtcctgtt gtactaaagg cgaaaataat
     6541 gaaagaaagg aagttctttg ttttgtcctt gtattttcct aaatgagcta cttcatctgc
     6601 taggaggcca cagataattc caggaaggaa ggaaccagca ccgtgtttag ttcccaagaa
     6661 aaagaaggca atgacaaggc cgatagtggt aatggctcca aagcgcggaa cttttgcgac
     6721 taggatcata tagacgctac cgccgacaag ggcagtaaag gcaggcgcat aaaacatgtt
     6781 tccagtttgg tcaaagagat tgcccaaaag gacaccaatc cccatgcaga ggaagtaaag
     6841 aactgcaaaa agcagtgtag ttaagataga ttttttcatg aattgtctcc tgataatttt
     6901 ttcacaattc tcattgtacc acggtttggt gggattgtaa atggatacta gaagtttttg
     6961 aaaacgcttg aaatatgata taatggtttc atagttattt ttaggggaat atcatgggta
     7021 gatttttaga ctttgtcttt aatcgtttct ttttagggat gattgcgaca gccttctttt
     7081 ggctattaac tttagcagga gggattatcc ttggtctagc gccggctagt gccaccttga
     7141 tgagcttata tgcagaacat ggttatagct ttcgggaata cagtttgaag gaggcttggt
     7201 ctctttacaa gcaaaatttt gtctcaagca acctgatttt ctatagcttt ttaggtgtgg
     7261 gtctagtttt gacctatggt ttgtatctct tggtgcaatt gcctcatcag accattgttc
     7321 atttgattgc gacccttttg aatgtcctag tagttgccct gatctttttg gcttatacag
     7381 tatctttaaa attacaagtt tattttgcct tgtcctatcg aaatagtctc aaattatcct
     7441 tgattggcat ctttatgagt ctagcagctg tggccaaggt tctccttggg actgtgctac
     7501 ttgtagcaat tggttactat atgcctgccc tgctattttt tgtaggaatt gggatgtggc
     7561 atttctttat cagtgatatg ttggaacctg tctatgaaat catccatgaa aaattggcga
     7621 caaaatagaa tgaagcagtt ttggctacat acgcttctaa gaacctatag ttcagtgatg
     7681 atcattatca ttgcgagttt tgcaatctta ctctcttacg ctgactggga ttcacgtgaa
     7741 aaggaagccc agagagtagc ccagcgtgta actgctagaa cagtgagtga aattgaatat
     7801 taccatagag agtcaaccca gatagctcag gctttagttg aaaaccaagc tcgtattgag
     7861 ggaatctata aatactttag ccttagcatg ccagactatt tttactggca attagagcgg
     7921 aaagcttcgc cttatatatc agtctctctg tatgaaaatg ttgatgacct ctatgttcga
     7981 aatgattttg taactggggt ggccattgct tttcaagatt acaaggaagt ctatgtttct
     8041 actaaagaca aacgtagtgg agaaaaaatc agggctgagg atttcaaacc agcaggaaat
     8101 agttttgcca ttccagtgtc agatccagtg tcagatcaag acttaggagt gatttacatc
     8161 tccttggatc ctgctgtttt ataccatgcc attgataata ctagaggtca tactccgatg
     8221 gcagtaacag tgacctcacc ttttgatacg gagatttttc atatgggtga gacagttgat
     8281 aaggagagtg aaaattggct agttggctta acttctcatg gttatcaggt tcaggtggca
     8341 gttcccaaaa actttgtttt acaaggaacg gtgaccagct ctgctttgat tgtgggcttg
     8401 agccttctct ttattgtcat tctttatctg actttgaggc agacctttgc taattatcaa
     8461 aagcaggtag tggatttggt ggattccatc caagctattg cccaaggaca agaaggtctt
     8521 cgcattgata cgcttgaaaa ggatcaggaa ttgctcctaa tcgcggagac gaccaatgat
     8581 atgttggatc gattggaaaa gaatatccat gatatttacc agttagaact cagtcaaaaa
     8641 gatgccaata tgcgggcctt gcaggcgcaa atcaaccctc acttcatgta taatacgctg
     8701 gagttcttgc gtatgtacgc agtcatgcag agtcaagatg agttggcaga tatcatttat
     8761 gaattcagta gtctcttgcg taacaatatt tccgacgaaa gagagaccct cctcaaacag
     8821 gaattagaat tttgccgtaa atacagctat ctctgcatgg ttcgctatcc caagtccatt
     8881 gcctatggtt tcaagataga tccagagtta gagaatatga agattcccaa gtttaccttg
     8941 caaccgctgg tagaaaacta tttcgcgcat ggtgttgacc acaggcggac agataatgtg
     9001 attagcatca aggctcttaa acaggatggg tttgtggaaa ttttggtggt cgataatggt
     9061 agaggaatgt cggctgaaaa gttggcaaat atccgagaaa aattaagtca gaaatatttt
     9121 gaacaccaag ccagctacag tgatcaaagg cagtctatcg ggattgtcaa tgtacacgag
     9181 cgttttgtgc tctattttgg agaccgctat gccattacta tagagtctgc agagcaagcc
     9241 ggtgttcagt atcgtattac aattcaagat gagtagaaag ggagaaaatg tataaagtat
     9301 tattagtaga tgatgagtac atggtgacag aaggtctgaa gcgtttgatt ccctttgata
     9361 agtgggatat ggaggtcgtc gcaacagcca gtcatgccga tgaagctcta gaatatgttc
     9421 aggaaaatcc tgtcgatgtc atcatttccg atgtcaatat gccagacaaa acagggcttg
     9481 atatgattcg ggagatgaaa gagatcttac cagatgctgc ctatatcctg ctctcaggtt
     9541 atcaggagtt tgattatgta aaaagagcaa tgaaccttag tgtggtggac tatttggtca
     9601 agcctgttga taaggtagag ctgggaaatc tgctggagaa gattgcaggt cagctcggcg
     9661 agagagggaa gaaaagtcag actcttagtc aagaattaga cgaggctgga tttgttagtt
     9721 atttagggga taaggagaat tggtggatag gtctatccaa ggaaaaacaa ggttccttca
     9781 ccattcccta ctatgtcttg ggccaagact ggcagatttt catttctgac caacccctag
     9841 atggtttagt cgttacacct tttgaagctc cttatcaaga acactttgaa cgctggaagc
     9901 tgaatgctga gaaaaccctc ttttacggtt ctgtaaattt gcagcagtct gagagtctct
     9961 ttgcctatta cgaaccgatt tatagggtta tcattcaggg aaatctcaat caaatcgtag
    10021 aagagttaaa tctcttggag aaggtagttc ttgaaaatac gccgcgtgtt ccgattacta
    10081 aacagctttt tattcagttt gtcatggatg ttttccattt atttgaacat ctcaaagctg
    10141 atgacctgac agacatcgtc aaaaccattc atgctattca atccttcgat gaattggttc
    10201 cttatatcaa ggaaactctg agcagctttt tcggtcaata ccgtatgaat gaaaatgtgg
    10261 tcagtgtgct ggaagtcatt ggtcgtgatt accaaaaaga gctttccctc aaggatatca
    10321 gtaaggctct ctttatcaat cctgtctatc tagggcagtt gattaagcgt gaaaccgatt
    10381 cgacttttgc agagttacta aacaaacaac gtattaaggc tgcccaacaa cttttgcttt
    10441 caactagtga cagcatcgaa gatatttgtt atgctgttgg ttacagtaac cttggatatt
    10501 tctataaagt tttccgaaaa ttgtgcggaa aatcgccaaa agcctaccga aaacaggtag
    10561 aaactatact ataagatttg tattccttta caaaaggtgc tataatatta tcaggaggtc
    10621 ctatcatgaa aaagaaacca atttatctat gggtcttgct aatcttgtct gcccttattt
    10681 cagttccgtc tctgtttgga attgtgagtc ccttgcctag taaagaagcc cttcgtgctg
    10741 ctcagaaaca agttgcaggg gtcaatgctc agcaattaga agaccagctt aattatacct
    10801 atagagtagc agaagcatct cattctattt ttaatgttgc tttgattgtg ctatctacta
    10861 ttttagtggt cgtagcgatt gtcttccttg ttcgtaaaaa tttgcaatat gcaaactata
    10921 cttacgttgg ctatgttttg ttagctatta ttggttcgat ttatggctat gttggtttac
    10981 aagacgctgt gcagttggtt caagatgaga gcatgcgttt gacagtgagt attggctcaa
    11041 aagctgttag cattttctat atcgtcatca atgttctctt cctagccctt gtcttctata
    11101 agatgtggcg acaacagaaa gccttggcag aagaagagga aacagaagag cttacctaag
    11161 tattgacaaa aaagaactat caagatacaa tcttggtagt tgttttttga ttatagataa
    11221 aatcatggag gtacatatga agacaatttc tttagtttat attagtttga gtggcaacac
    11281 tgaaagtttt gtgacgcgct tgaaagacta tctcttgtcc cagtacaaag ggattgaggt
    11341 tcaaaagatt catatcaagg atttggtcaa ggaaggcaaa aatttctatg aaatggacca
    11401 tccctatgtc gcttttttgc cgacctatct cgaaggtggg aatggcgtgg ataacggaga
    11461 tgttgagatt ttgacgacac cggtgggaga ttttattgcc tatggtaaca atgctagtaa
    11521 gtgttttggt gtggttgggt caggaaatcg taactttaat aaccaatact gcctaacagc
    11581 caagcaatac agtcaacgct ttggcttccc tgtattggct gactttgaaa tgcgaggcat
    11641 gctggaagat atcaaacatg tcgcagctat tatcgcagat ttgtatgagt tggaaaagga
    11701 gaattaatac tcaatgaaaa tcaaagagca aactaggaag ctagtcgcag gttgctcaaa
    11761 gcacagcttt gaggttgcag atagagctga cgtggtttga agagattctc gaatagtata
    11821 aagttcttat aagaggtggt tgaagttgtt caactgtttt ttgagtataa acagtcttta
    11881 agaacgtaaa aaagcataag ttcaggtctt caaaaccttg ttcttatgct ttttatcata
    11941 gaaatatttg ctgaattttc tcttgaaatg aaaccttatc ttcatctcgc gcttgtccct
    12001 taccctgctt ttccgattgc gagtgcgtag ataaagaaga tggcgaagcc aaagaggaaa
    12061 atcaatcccg caatggcaag gtgtttgagc caagaaggaa gatttttgtt ttcacgcgtt
    12121 accaaggcgt aattcaaaag agcaaagaaa ggtgttgtca ggaaagatcc aatcatggca
    12181 aagcggagca tggttgaaac ctgaccagcg aagaacttga taatgacgat accgatgata
    12241 gcagtgatgg tcatccagat gttcaaagat ttacgattgt cctctttttg actgattagc
    12301 agtcggagag attcctgatt aacgcgagaa tagccatcga taacagttat aactgttcca
    12361 aagatacaga ggaaggcaat aaaggtaatc aagtaacggg accattcgcc aagaacagag
    12421 gcatacatgc ccacgaattg agagatgtat ttggctgaag cagcttcaac cgcctgccct
    12481 gtaggatact gaatcagtgc tcccagtgcc acaaagaaga cggctaggat agctgttcca
    12541 atataaccag tgttaaagtc aaacagagcg tcttctgtgt taaagttgac ggtctttctc
    12601 ttttcagctg accaaagtga attgatggct gaaatttcaa taggagccgg catccatcct
    12661 aggagggaga cgatgaaggg cagagctgcc atttgccaag gtgtcttctc gacaaaatca
    12721 gaactgtatt ctggatgctt gaccgccgca atgataactg caagaacagt cgcaatggtt
    12781 aaggcagaca taatccattt gaccatgccg tctaaaagtt tgtagcctcc aaagagtagc
    12841 atagcccaaa tgattgcaac gagaatgagg gaccactgag taatgctaag tccaatcatt
    12901 gggaaggcac tggcgatgat agctgagcac agaatggcaa caccagccgt gttgaccata
    12961 gccgaaaaga cattgagaat aaagaaaatc cagagataga gttttccttt ttcggcataa
    13021 ccttcaacca aagtctttcc agtatcagct gtgtattcag caccaaaacg gaaaaatgga
    13081 tatttaaaga cattggctaa gatgaccaag agaagtagag accaaccgta agaaccgcca
    13141 gcttgagttg aggatacaat gtgggaacct ccaacagcgg cagttgccat taggattcca
    13201 ggtcccattg cttttagctt gcttgcccag gttgattgat ttaaggaaat agcttgcgac
    13261 atgataaata ctcctttttg aattttcaga ataatctgta tatgcaatct atattctaca
    13321 aaaaattttg gaaaaatgca agaatatttt gaaaaaagat agaaaattta caaagaaaat
    13381 ctgaaataac tgttatgata tag
//
LOCUS       DBERXF010000050        13289 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.50, whole genome shotgun sequence.
ACCESSION   DBERXF010000050 DBERXF010000000
VERSION     DBERXF010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13289
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.50"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            103..450
                     /locus_tag="ACL8JK_001856"
     CDS             103..450
                     /locus_tag="ACL8JK_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGS1786681.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(729..1565)
                     /locus_tag="ACL8JK_001857"
     CDS             complement(729..1565)
                     /locus_tag="ACL8JK_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1786682.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(1578..2207)
                     /locus_tag="ACL8JK_001858"
     CDS             complement(1578..2207)
                     /locus_tag="ACL8JK_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS1786683.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(2217..2858)
                     /locus_tag="ACL8JK_001859"
     CDS             complement(2217..2858)
                     /locus_tag="ACL8JK_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS1786684.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(3004..4233)
                     /locus_tag="ACL8JK_001860"
     CDS             complement(3004..4233)
                     /locus_tag="ACL8JK_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGS1786685.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSNLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(4223..5389)
                     /locus_tag="ACL8JK_001861"
     CDS             complement(4223..5389)
                     /locus_tag="ACL8JK_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGS1786686.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            5533..6546
                     /locus_tag="ACL8JK_001862"
     CDS             5533..6546
                     /locus_tag="ACL8JK_001862"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGS1786687.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNNTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(6591..7010)
                     /locus_tag="ACL8JK_001863"
     CDS             complement(6591..7010)
                     /locus_tag="ACL8JK_001863"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGS1786688.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(7021..8427)
                     /gene="atpD"
                     /locus_tag="ACL8JK_001864"
     CDS             complement(7021..8427)
                     /gene="atpD"
                     /locus_tag="ACL8JK_001864"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGS1786689.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(8513..9391)
                     /locus_tag="ACL8JK_001865"
     CDS             complement(8513..9391)
                     /locus_tag="ACL8JK_001865"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGS1786690.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(9407..10912)
                     /gene="atpA"
                     /locus_tag="ACL8JK_001866"
     CDS             complement(9407..10912)
                     /gene="atpA"
                     /locus_tag="ACL8JK_001866"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGS1786691.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(10927..11463)
                     /locus_tag="ACL8JK_001867"
     CDS             complement(10927..11463)
                     /locus_tag="ACL8JK_001867"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGS1786692.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(11463..11957)
                     /gene="atpF"
                     /locus_tag="ACL8JK_001868"
     CDS             complement(11463..11957)
                     /gene="atpF"
                     /locus_tag="ACL8JK_001868"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGS1786693.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(11971..12687)
                     /gene="atpB"
                     /locus_tag="ACL8JK_001869"
     CDS             complement(11971..12687)
                     /gene="atpB"
                     /locus_tag="ACL8JK_001869"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGS1786694.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(12722..12922)
                     /locus_tag="ACL8JK_001870"
     CDS             complement(12722..12922)
                     /locus_tag="ACL8JK_001870"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HGS1786695.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(12997..>13289)
                     /locus_tag="ACL8JK_001871"
     CDS             complement(12997..>13289)
                     /locus_tag="ACL8JK_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGS1786696.1"
                     /translation="EFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRRWLPKGTK
                     KMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRFQ"
BASE COUNT         4087 a         2945 c         2367 g         3890 t
ORIGIN      
        1 aaaagatgag accaaccaac ctcatctttt ttcgtatcaa atctaagcaa ttttagaaac
       61 tttatggcat actagactta tcaatgaaag cgaggtaatc tcatggaaca atttttagat
      121 aacatcaaag accttgaagt cactacagtt gtgcgtgcgc aagaagctct tgataaaaaa
      181 gaaactgcaa ccttctttat cggtcgcaaa acttgccctt actgccgtaa atttgcaggt
      241 acattgtcag gtgtcgtagc tgaaaccaaa gctcacattt acttcatcaa tagtgaagaa
      301 ccaagccaac tcaatgattt gcaagcattc cgctcacgct atggaatccc aactgtacca
      361 ggttttattc atattacaga tggacaaatc aacgtccgtt gcgactcttc aatgtcagca
      421 caagaaatca aagatttcgc aggattgtaa aaaatcagct aacaagtctt aaaatcacaa
      481 aaacgcataa tgtaaggtgc aaaaaccttg atattatgcg ttttattgtt cctaaaacag
      541 ttacatcagc atttcattac agaacatttt aattttggaa gtcaaatcaa tttttaacaa
      601 tattttagaa atcacagtgg gctattccat attcaattat ccagattcaa tcgctattat
      661 cgttttccta gattacaaaa aaaactacgt tttgctaatc aaaacgtagt ctcagccact
      721 attttatctt actgtccttc ttttacttct ttggttgcta catcttctcc aaaccatttt
      781 tggctgattt cttggaactt gccgtccttg taaagactag aaaaagcttc atttatcttc
      841 ttaaccaagg ttgtatcttc cttacgggct ccaaccgcaa aagcttctgt ttctagtcca
      901 actgtaaaga cattataatc gtttaaaaca ccttctgctt ctaaataata gtttgcatag
      961 acacggtcaa tcaatagacc atcaattcga tcgtttttca aatcaatcaa ggcttcatta
     1021 aaggtttggt attgattcgc ttccttatta gcgacaatat tcttcaaaag ttctggattt
     1081 gcttcaaagt ccgcataacc agatgaacca gcttgagctc ctaatgtctt tccagtcata
     1141 tcctttgcag tcgtgatacc agatgatttc ttcgtaacca atacctgctc attcttcata
     1201 tatgagttac tgaaagccac cttttcacgg cgttcgtctg tagcggaata gccattccaa
     1261 atcagatcaa tcgttccttt tgtcaattca gcttctttca aatcccaatc aatcggttgc
     1321 caatttaccg tgattccgta tttttcaaaa acagctgtag ctaaatcaat atcaaatcct
     1381 gcataagaac catctttctg agcaaatccc attggaacaa aagtactatc aaatccaata
     1441 gtaatagact tgttagactg gtactttgac caattatctc cactagtttc gctagaattt
     1501 ttcccacaag ctactaagaa caaagcagtc atcagactga ctaatacaag catccatttt
     1561 ttcatccatt tttcctccta tttaggttct actttcaata atacatctgc gatattttca
     1621 gcaaactgca aatcatgggt aaccacaatc tgggtcatcc caagttccct attttgcaag
     1681 attagcttct ccacttccaa acgtaattct ggatccaggg cagaagttgg ttcatcgtag
     1741 ccaatgattt ctgggtcaat catcatagca cgcgccaaag ccactcgctg cttttgccca
     1801 ccagatagtg agaaaggata ggcctctgcg tgtcctccta gtcctaactg ttccaagagt
     1861 ccactcgcct tcttctcagc ctcttcctgc ttcattccca tggtcttcac aggcgataaa
     1921 gtcaaatttt ccagaactga tagatgagga aatagttgaa aatcttggaa gacaaatccc
     1981 agtaggttgc gcttctgcaa ttcatccagc tctaaaggtt gtccattata aaagatttgc
     2041 cctgaatcaa tggtttcaag acctgcaagc atacgtaaaa gagttgtctt acctccacca
     2101 gaaggtccaa cgatagccag gatttgcttt tcaggaatac ttagactgaa attagacagg
     2161 atttgtttgt ctccaaagac tttattgata tttcgtaatt ctaacatggc agcctcctat
     2221 ctataataac tatacttctt ctcaactttt ttggaaataa ttgtcacaat cccaatcaaa
     2281 atcaaataaa tggctcctgc caagaacata ggaactagac tagcatcgcg gttagcagct
     2341 gttcgactag ccaagataag gtctgaaatt ccgagagcat agaccaaaga agtatccttg
     2401 accaaactca taacttcatt aaagacacta ggaagaacaa tcttggtcac ttggggcaag
     2461 ataatatagc gcactctgtc aaaagggcta aactttaaga ccttggcagc ctcatactgt
     2521 cctcttggaa tagtgtcaat tcccccacgg aaaatttctg caaagtaagc tgcatagttg
     2581 agaacaaagg caataatagc tgcaggaagg cggtctaaac gaatcccaat acttgggagc
     2641 acataataga taaaaatcag ttgcaagagt aagggggttc ctcgcataac ccagatgtaa
     2701 atgttaatca gataatggag gggcttccaa tggacttgca aggcaaaggc aatcaaaacg
     2761 cccaagggaa tcgaaaatag caagaccagt gcaaagacct gtacagtcgt gctcgcacca
     2821 ttcagtaaac tcggtaatat ctcaaataaa taagacatac tgcacctcct aaaagtaatt
     2881 gttcctatta tagcatgaat aaacaagatt accaagtatt tttgtaaaaa gattctacca
     2941 tatacaaata aaaaccgtag ctatcaaaag agataaacta cagttctata tgtttaaaca
     3001 ttcttacaat ctctcaaaca gttcttgcat ttgcacatca tctggaacca gttttaagta
     3061 agtgtgagca tggacttttg cttcttcaaa atgtcccaat tcacgcaaga gatagatata
     3121 gtgttccaga aattctggat tgtccttcaa atctcctgtc aactcttgat aatgctcata
     3181 agcagtatcc aaatcgtcca tttcttgata agaacgagca atcatccact tggtcaaaag
     3241 attttctggc tcctcactct gcaagtctag aatatcctca taacgctcct gctccagata
     3301 aatagtggct aaacgaagca agatttcttc tgtatcctca gcgtcttctt ttgcagtaag
     3361 gagataattt tctgcaccac tagcatcatg caattcataa gaaaattgtg aagcagctag
     3421 caagaggcga gtttcaaagg gatttttctc taatccttgc ttagcgatac gcagggcttc
     3481 ttgaacttga tgttccttat gtaaagcctg actgtaccca tactcatagc cttcaaagtc
     3541 aggagaaatg gtatcaagct gcttaaagta gagggtggct ttttgatatt cttcttgatc
     3601 aaaataaaga ctggccaact caaaagctgt taagtcatcg tattctaact ccagggcttt
     3661 ttctaaaaac tcagtagccg tttcaaattt ccctaactga gcataggcaa agccaattcg
     3721 ttgataggtg gaaatgcccg tttgctcata aatcgagcga ttatctaact gggcataggc
     3781 ttgaatagcc gcttggtaat tttccaactc actatccaac tctgccaaac ccaatatcaa
     3841 gagagaatcc tctgagtagg tcaaggcctc caataatttc tcacgtgcca catctgtcaa
     3901 accttccagc tggtaaaggt ctgccttcaa aaccaaagac gagacatacc agtcactgtc
     3961 agcttggatt tcctcaagat aggtaaaggc ttcttctatt tgaccatcct cgctagcaat
     4021 tgcagctaga ttaagatgaa cctctggaaa atcctctaca attttcaggt aaatttcctt
     4081 ggcctgagga tagaaaccaa tcccttcaag ataagttgcc aactcataca gaagattact
     4141 tgaatcattt tctaaagctt tggcgaaata atgctcagcc ttagttaaat cttgctcctc
     4201 caaagcctgt aacatctgtt gactattgtt cactcttgac ttcctcaccc tctaattcat
     4261 atagaccact gactacctta taccattcga aaatggctga aatgacaacc ttagcagagg
     4321 cataaaccgg aataccaagt aaaactcccc agataccaaa catagatcct gaagttaaca
     4381 aaacaaagag aacattaata gggtggatgt ttaattgact tcccaaaatc aatggagaga
     4441 caaaacggcc ttcaatagtt tgttctacga taaagacaat cactactttc aaaagcatga
     4501 ctggaccagc aatcaaaccc aatactagag caggaagcat ggctagaaag ctaccaagat
     4561 aagggaccag atttaaaata ccagcagtaa cccccagcgt aaccgcatag cgtagaccaa
     4621 taatcttgaa gaagatgata aacattactg ctacaataat agccactgtc acttgccctc
     4681 gaacatagtt ggacaactgt tgattcacat ctgataaaac ttgtccaaca ggttccttca
     4741 attttcttgg aatgaattgg gtcaaatagt tacgcaagcc tttcccatca cgcaagagat
     4801 aaaagagcat gaaaggaacg ataatcaagg caacaatcac ttgagaagcc ccgctaataa
     4861 aggcactcac ccagttgact gcctgagatg aaaccttact tgccaaaact gtagcctggc
     4921 tagaaaaatt ggtcaaaact tgctctaatt gaggtctgaa atcatctggc aggtgctggg
     4981 ctaccaatcc attaacaatc ctatctatat cttctaagta aacaggaacg tttcttgcaa
     5041 aggtcaaaac ctgacgttgc agatttggaa tggcgactgc caagccccaa atgataaaga
     5101 gagcgatgat aacaaagaca atagtgatag ctataacacg attaacctta tgcttctcca
     5161 tccaatcaac aataggattc aacaaataat ataacaaacc agacaaaatg actggcaaca
     5221 tcacaactgc taaaaagtct aaaacaggtg aaaatagaaa actaatctta cttaaaataa
     5281 aaagattcag tcccaataat aaggttacta aaaataccgt aattgccttg ttatctaaaa
     5341 accacttgaa aaaccaagat aggctaaaat gtttctcttt ttgctccata aatacttcct
     5401 ttctattgtt ctctcattat accatttttg aaacaaaata actctttttt aaagtgctta
     5461 catctaattg gatatcttta atttacttgt ttttgtgata taatagtctt atctttacac
     5521 agaggtatag taatgaaaga aactgtttat tttggaactt atacacgtcg tacttctcaa
     5581 gggatttaca aggcagactt tgatacagaa actggtcagc tttcaaatct agaacttttt
     5641 gcagctgagc caagtccaac ctaccttgcc tttgaccagc accaacattt atacactgtt
     5701 ggtagccaag acgataaggg gggaattgca gcctatcaaa ctgacgggac tgtgttaaat
     5761 catgttgttg aagaaggagc tccccactgt tatgttgctg tcgatgaaaa gcgtgatttg
     5821 gtttacgcag ctaactatca caagggacaa gtccttgttt ataaacgcca ggaagatggt
     5881 agtcttctac ttagtgatat ggatcaacac agtggccaag gtccacatga aaatcaagct
     5941 tccccccatg ttcactatac agatttaaca cctgaccact atctagtgac ctgcgacttg
     6001 ggaactgacc aagtcatcac ctatgacctc gatcaagaag gaaaattatc taagctctat
     6061 acctatcaca gcaagccagg agcaggctca cgccatatca ttttccataa ccactataaa
     6121 atcgcttatc tcatttgtga actcaataat actatcgaag ttttaatcta cgatggcgtt
     6181 ggcgaatttg aacgtatgca ggtcatttca actttaccgg aagcttacga aggctttaat
     6241 ggaaccgctg ctattcatct ctctaaagac ggtaaatacc tctacgcttc taaccgtggc
     6301 catgattcta tcgcagtata taccatcctt gcggacggta gcttagagtt attagaaatc
     6361 gttccaacgc atggtcagac tccacgtgat tttgatttga cacccgacca aaaatttctc
     6421 attgttgtcc atcaagactc tgacaatgca actgtcttta aacgtaattg tgacaatggt
     6481 cgtctagcag aactctccaa cgacttccat gttcccgaag cagtctgcat ccgttttgct
     6541 ccttaaaaca ccataaaaaa tgaacttggt attttcaagt tcattttttc ttatagtcta
     6601 tttccgacat taatacggtt aatggcacgt tgcaaagcaa tcttagcacg acgttcttgg
     6661 tcaatcaaat gtttgtcttg tgcttcttca attgcacgtt ctgcacgaag tttggcacgt
     6721 tctgcacgac tgatatcgat atcacgagca cgttctgcag agtcagcgac gattgtgatc
     6781 atatcattgg caatttcaat aacgccaccg tttactgcaa tccagttcac gtgatcttta
     6841 tcatcgatac gttttacctt tacttcatca actgctaaaa ccgcaatcat attttcatgt
     6901 cgtggcaaga tccccatctc accatccaga gttcgaaccg atacatagct ggcatggtga
     6961 tcatagacga gaccatctgg tgtcacgatc tggacagtta actgagccat agatcacctc
     7021 ttaaaatccc attttttcag cttttgcaat cacatcttcg atagaaccta caccacggaa
     7081 ggcatcttct ggcaagtggt cgtatttacc atcaaggatt tccttaaagc cacgtacagt
     7141 ttcagcaact ggaacataag aacctggctg accagtaaat tgttccgcaa cgttgaagtt
     7201 ttgtgacaag aagaactgga tacgacgggc gcgagcaacc aaggtctttt cttcatcaga
     7261 aagctcatcc ataccaagga tagcaatgat atcttgcaat tcatggtaac gttgaaggac
     7321 acgttttact tcagcagcaa ctgcatagtg ctcttctcca acgatttcag gtgccaaggc
     7381 acgtgagctt gaagcaagtg ggtcaacggc tgggtagata cccaattgta ccaacttacg
     7441 ttccaagttt gttgttgaat ccaagtgagc gaaggctgtt gctggcgctg ggtcagtata
     7501 gtcatccgct ggcacataga tagcctggat agaggttaca gaacccttct tggttgatgt
     7561 gatacgttct tgcaattgac ccatttccgt agcaagtgtt ggttggtaac caacggctga
     7621 tggcatacga cccaaaaggg cagatacttc tgaaccagcc tgagtgaaac ggaagatatt
     7681 atcgataaag agaagcacgt cttggccttc cacatcacgg aagtattcag cgattgtcaa
     7741 accagtaagg gcaacacgca tacgtgctcc tggtggctca ttcatctgac caaagaccat
     7801 ggctgttttc tcgataacgc ctgattcttt catttcccag taaaggtcat tcccctcacg
     7861 agtacgttcc ccaacaccag taaatactga aataccaccg tgctcttggg caatgttgtg
     7921 aatcaattct tggattaaga cggttttacc aactccggca ccaccgaaaa gtccaacttt
     7981 accaccttta aggtaagggg caagaaggtc aataaccttg atccctgttt caaggatttc
     8041 agaagaggta gacaactcat caaaagttgg agctttttta tgaattggct gacgctctgc
     8101 gtcttctgta aaaggagctt ccaaatcaat ggtatctccc aaaacgttga agacacgtcc
     8161 caaagtttct ttacctactg gtacagagat tggacgacct gtgtccaata cttccattcc
     8221 acgagtcaac ccatctgttg attccatggc gatagtacga accataccat ctcctaactc
     8281 caaggctact tcaaggacga tttttgtttt tctttcgtca tttttgtaga cgacaagtgc
     8341 attgttaatc tcaggaagtt tttcccctgc tgcaaacaaa acgtctacaa cgggaccgat
     8401 aacctgagca attttacctg aactcatctc cttctcctat tctatataag atactgtcgg
     8461 ttcctagctc aactaggtcc taagttcatt ttcatacgag ctggactaga gcctattcta
     8521 aggcactagc acctgctacg atttctgtaa tttcttgtgt aatcgccgcc tgtctggcac
     8581 ggttatactg aattgtcaaa tcattgatga ctttcttagc attatctgtc gctgtttgca
     8641 tggctgtcat acccgcagca ttctcagctg tcttggcatc gataatggca ccgtaaatca
     8701 tactttctgc aaactgaggc aacaactgct ccagaatttc ttctcggctg gtttccaatt
     8761 caaaagtcaa gctgtactct tcatccgctt catttggatc caagtcaaca atcggaagca
     8821 tttgttccac acgcatttga ctggttagcg tattgacatg gtggttgtag caaacataaa
     8881 gctcatcaaa gagttcattt tggtacattt caacagtttt tgaaataatc ttacgaactt
     8941 gatcaaagct aggttggtct gccaagccac gtaattcata aagtggttga ataccgcgag
     9001 ccttaaagaa atcagctccc atcccaccga tacagatcat ttcaaaacct ttaccgtctg
     9061 ggtggtattc ttctttcaac tccataacag ctttcaaaat agaggaatta taacctccaa
     9121 ccaaaccgcg gtctgaagtg ataacgatat agcctgtctt cttcacagaa cggctaatca
     9181 acatcggatt agttgaagca ccagctccat taccatgaag gatatctgtc aaaagtttac
     9241 gcactttctg agcgtaaact tggaagttgc gagcagcttc ttcagaacga cctagcttag
     9301 cagccgatac catttgcatg gcattagtga tttgactcgt attttttgtt gaggcgattt
     9361 ttgttttaat atcatttaga gatactgcca tctgacacct ctattcttat tggaagctag
     9421 attgattgag aaactctgta atcgcagcat ccaagactgc ttcttctggc aagtcttttg
     9481 tatcacgaat ggtttccaaa atctctggat gttgagcatc aaagaaggta tggaactctt
     9541 cctcgaaacg aacaatatca tctactggaa cagtatccaa gaaaccatgt gtcaaagcat
     9601 aaagaatggt tacttgtttc tcaacaggta atggtttgtg aacaggttgt ttcaagacct
     9661 caacggtacg acgtccacgg ttcaacttag cctgtgttgc tgcgtccaag tcagaaccaa
     9721 acttagtaaa ggcttccaac tcacggtatg aagcaaggtc gatacgaagt gtaccagcaa
     9781 ccttcttcat ggctttgatt tgtgcagaac cacctacacg agatacagat gaacccgcat
     9841 cgatggctgg acgaatacct gcattgaaga ggccatcgcc aaggaagatt tgtccatcag
     9901 tgatagaaat cacgttggtt gcgatatagg ctgagatatc tcctgcttgt gtctcgataa
     9961 atggtagggc tgtaattgat ccaccaccaa gttcatcaga aactttagct gagcgctcaa
    10021 gcaaacggct gtggagatag aaaacatccc ctgggaaggc ttcacgacct ggaggacgac
    10081 gaagcaagag cgacagttca cgataagcta ccgcttgttt tgatagatca tcgtatacaa
    10141 tcaaaacatg cttaccttga tacataaatt cttccgccat agcaacccca gcataaggag
    10201 ctaggaagag caatggagat ggttgtgaag cagaggctgt cacaacgatt gtgtagtcca
    10261 aggcaccgta ctgacgaagt gtttctactt gcgtacgaac tgttgattct ttttgtccaa
    10321 tcgcgacgta gatacagatc atatcttgat ctttttggtt caagattgta tcaatcgcaa
    10381 tggttgtttt ccctgtctga cggtcaccga taatcaactc acgttgacca cgaccaatcg
    10441 gtacaagggc gtcaatagct ttcaaaccag tttgcaatgg ttctgaaaca gacttacgtt
    10501 gcataacacc aggagctggt gcttctactg gacgagtttt atcagtgtgg atttctccaa
    10561 gaccgtcaac tggacgacca agcggatcca caacacgacc aatcagactt tcacctacag
    10621 ggacttccat gattttccct gtacggcgga ttgtatcgcc ttcacggata tctgtaaagt
    10681 cacctaggat gataatacca acgtctgttg actccaagtt ttgagccata ccataagagc
    10741 cgttttcaaa attcaacaac tctccactca tgacattttc aaggccgtga gcacgcgcga
    10801 taccgtcccc gatataggtt acaacacctg tttcagtcac atcaaaattg ggtttgaaat
    10861 tttcaatttg ttgcttaatt aaagcgctga tttcttgtgc gttaattgcc aaaagaacac
    10921 cactttctat ttcaaatttt ctttaacaac tttaagttgt tgtttaatac tcacatcaat
    10981 tgtcttgtga ttggcaaaaa tgacaaaacc accaatgaga ctttcatcga tttgttcttt
    11041 tacactcctt actttcagag acattttttt ctcaatcaaa gggagcaaac gagtcttctg
    11101 ttcatcagtt agaggatgag cagacgtaat cgtcacttca aatcgatttg tttctttttc
    11161 aagtcggttc aagcaatcta caagcacatc ataaaaaaga tttgctctat gattgtaggc
    11221 cagaacctgg ataaagtttt gtaataaagg tgacacagaa tcttggaaaa aagcaattgt
    11281 tttttcctta tccgactcgt ctactgccac ttgctttaaa aaagaaggca gacctgtttt
    11341 ttcaacaact tgcttgattt gagtcaagtc tgaaaagata cggtcttctt ctcctttttc
    11401 aagtaccaat tggacaaaag gcatgctata tttttcaatt acctttactg ttttcttgtc
    11461 cattaagctt ctcctagctg atcgatatac tgatcaatga gtgctttatg ggcatgactg
    11521 tcaaggtttt gtgagatgat tttaccagct aagctgatgg tcaaatctgc gacctcaccc
    11581 ttaacactct gtaaagcttc tactttattt tgagcaattt cttgattggc tttttctttt
    11641 aagtgtcctg cttctagttt agcatctgct aagatattag ccttactttg ctcagctgtt
    11701 tcctttgcat tttcaatgat tgtcttagct tctttacggc taccagccaa ttcatcttcg
    11761 cgtttttgag ccaatacttc tgctttttga cgggcttctt cagctctgtc aatatctgaa
    11821 gcaatttttt cagctctttc ttcgaaaatg cctgtaatat tagaccatgc aaatttttta
    11881 atcaagacta gcaaaagaat aaaagagcca gtgattaaaa taaaattacc aattaattca
    11941 cctactgtta cgtgcatcag ttactccttt ctattcctct tcaatattaa tcttattccc
    12001 taaatacaca gatgtcaaaa gagtaaaaac ataagcttgg atgcaggaaa taaagacaga
    12061 aaatgcagtc caagccaaat tagctccaaa ggctactgga taccaataaa tagcttggtg
    12121 ggaaagaaga agtaacaaac tcgtcatgac ctctcctgca aagatattcc caaaaatccg
    12181 caaagccaaa gataagaagt ttgtaaattc ttccaagata ttcatcggta tgacaaaaac
    12241 aggactcata aaagatttta tacttttttt aaatccacga cgacgaacgc tttctatatg
    12301 tgtcaacaaa atgacaagaa aagataaggt taagtcatac tgtaaattag cggttggcga
    12361 actccaccag ttagtcccat cgatcgtttg aagctttgtc attaagccaa ggttattggc
    12421 aatcaccatg aaaaggaata aacaaaggaa aaagagtgag taatctttca tgtagcgcga
    12481 accaatgtta ggttctgtaa atccaataac aaagtcatag acatactcaa gtacattttg
    12541 ctttcctttg ggtttcaagg tcatattgcg gcttgcccaa taaataaaga caaaaataac
    12601 tcccacaatc aacaaagtca tggctaacat agtcagattg aagataacag gaccaataga
    12661 gatgattgga ttaatacttt cttccatcta aaatcctccc ttttcttctc gttccatgta
    12721 tttatttgat aataaatgag aagacaagag ttacaaagaa agttccttca ataaaggcaa
    12781 cacctaaaaa catcaaacta cgaaactcag aaagcatatc tggttggcgt gctactgatt
    12841 taaacagtcc attcatcaat aaaccttcac cgacagatac gcccatacag gcaatacata
    12901 agcctaaaaa tgttaaattc ataacaaatt ctcctttaaa ataaaattta cttacttagt
    12961 gtagtcctaa aatttaaatt tgtcaacttt taaccgctat tggaagcgtt taataaaaat
    13021 tatttccatt ttgctaaatt tcaagttcaa gttagccatc cagaagtctt ctctgggtga
    13081 cttgtagtcc aagcattttt taggatagtt gttaatccac ttttcgatga atgcgacttc
    13141 tttgggagtc attttcttgg ttcccttagg taaccatcta cgaatgagcc tgttatgatt
    13201 ctcattagtt cccctttccc aagaggcata ggggtgcgca taatagatgt gctcctcaga
    13261 aaatacatca aacaagcgat tgaattccg
//
LOCUS       DBERXF010000051        13263 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.51, whole genome shotgun sequence.
ACCESSION   DBERXF010000051 DBERXF010000000
VERSION     DBERXF010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13263
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.51"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(120..557)
                     /locus_tag="ACL8JK_001872"
     CDS             complement(120..557)
                     /locus_tag="ACL8JK_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGS1786697.1"
                     /translation="MSQEVINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(642..3275)
                     /gene="polA"
                     /locus_tag="ACL8JK_001873"
     CDS             complement(642..3275)
                     /gene="polA"
                     /locus_tag="ACL8JK_001873"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGS1786698.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDY
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            complement(3773..4718)
                     /locus_tag="ACL8JK_001874"
                     /pseudo
     CDS             complement(3773..4718)
                     /locus_tag="ACL8JK_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175244.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            complement(4836..5804)
                     /locus_tag="ACL8JK_001875"
     CDS             complement(4836..5804)
                     /locus_tag="ACL8JK_001875"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGS1786699.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(5949..6618)
                     /locus_tag="ACL8JK_001876"
                     /pseudo
     CDS             complement(5949..6618)
                     /locus_tag="ACL8JK_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family glutamic-type intramembrane
                     protease"
     gene            complement(6643..7140)
                     /locus_tag="ACL8JK_001877"
     CDS             complement(6643..7140)
                     /locus_tag="ACL8JK_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HGS1786700.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(7213..8574)
                     /gene="radA"
                     /locus_tag="ACL8JK_001878"
     CDS             complement(7213..8574)
                     /gene="radA"
                     /locus_tag="ACL8JK_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016893792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGS1786701.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(8588..9103)
                     /locus_tag="ACL8JK_001879"
     CDS             complement(8588..9103)
                     /locus_tag="ACL8JK_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS1786702.1"
                     /translation="MKIIFVRHGEPDYSELEERSYIGFGINLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(9105..9548)
                     /locus_tag="ACL8JK_001880"
     CDS             complement(9105..9548)
                     /locus_tag="ACL8JK_001880"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGS1786703.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(9605..9702)
                     /gene="ffs"
                     /locus_tag="ACL8JK_001881"
     ncRNA           complement(9605..9702)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACL8JK_001881"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(9735..10202)
                     /gene="tadA"
                     /locus_tag="ACL8JK_001882"
     CDS             complement(9735..10202)
                     /gene="tadA"
                     /locus_tag="ACL8JK_001882"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGS1786704.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGATGSLYDILTDERLNHRVEVETGILEDECAAIMQDFFRNRRKK"
     gene            complement(10403..11689)
                     /locus_tag="ACL8JK_001883"
     CDS             complement(10403..11689)
                     /locus_tag="ACL8JK_001883"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGS1786705.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGIGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGARNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(11920..12156)
                     /gene="comW"
                     /locus_tag="ACL8JK_001884"
     CDS             complement(11920..12156)
                     /gene="comW"
                     /locus_tag="ACL8JK_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma(X)-activator ComW"
                     /protein_id="HGS1786706.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            12416..13231
                     /locus_tag="ACL8JK_001885"
                     /pseudo
     CDS             12416..13231
                     /locus_tag="ACL8JK_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259226.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4121 a         3212 c         2202 g         3728 t
ORIGIN      
        1 gtatctacaa cctcaaaacg gtgttttgag cagcccgcgg ctagtttcct agtttgctag
       61 tgtgctcttt gattttcatt gagtataaca caaaaggtag cccatcagct acctttttct
      121 tatgcttcct caatcaagcg agtatgttct ctcttgatac agcgattcat cacgatatca
      181 tcacatccac catcacgcaa aatctctttc gcttctaaac tttcaagtcc tagctgtgcc
      241 caaaaaatct tggcatcagc tttgagaaaa tcacgcgcca catcgggcag aaattcactg
      301 cgacgataaa cattgacaat atctacagga aaaggaattt cagcgaggct agcataagcc
      361 ttttcaccca agatttcgcc acctgccgcc ttgggattga ctgggatgat tttatagccc
      421 cgagcctgca tttcctttgt cactcgattg ctggttgttt cttcacggtc agacaaaccc
      481 accacagcaa gggttttact cgttgcgaga tactgacgaa tcacgccatc acttggattg
      541 ataacttctt gactcataga aatcctcctt tttcatcagt atagcacatt ttgaaaaggt
      601 ttgcagaatt ctactacaaa aaaggaggac tagccccctt tttatttagc ctcgtaccag
      661 gttgcccctt cattctcatc tgcgataaga ggaacactga gttgaatggc ttcttccatg
      721 gtttgtttca ccaatttttt catctctacc aattcagatt taggcacttc aaggacgatt
      781 tcatcgtgca cttgtaacag catcttagtc tgataaccac ctgcaaccaa ggctttatcc
      841 agctgaatca tggcaatctt gagaatatct gctgccgaac cctggatagg tgagttgata
      901 gcagttcgct ccgcaaaacc acgaatattg aagttgcgcg aattgatatc tggcaactca
      961 cggcgacgct taaagagggt ctctacatag cccttatcac gcgcctcccg caccacttca
     1021 tccatgtagt ttttaatacc tggaaaacgt tcaaagtagg tatcaatgta ggctttggct
     1081 tccttacgac taattcccaa attattagac aagccaaagt ctgaaatccc ataaaccact
     1141 ccaaagttaa ctgccttggc attgcgacgg tcatttgcag tcacattatc aggacgctca
     1201 atgccaaaga cccgcatggc tgtcgaagta tggatatctg ccccctcttg gaaggcctta
     1261 atcaagtgct catccttaga aatatgcgcc aaaacgcgca attcaatctg tgaatagtca
     1321 gagctgagta gcacactatc ctcccactct ggcacaaaag ccttccgaat caagcgccct
     1381 tgttccaatc gggcaggaat attttgcaag tttggatcca cactagacaa acgcccggtc
     1441 tgggtcaaat cctgcatata gcgagtatga atctttccat cagccaaaat ccagtcctgc
     1501 aagccaatta cataagtaga ttgaatctta gcaatttgac ggtaatccag gattttctta
     1561 acaatcggag caataggagc gagacgctcc aacacatcca ctgctgtcga ataacctgtc
     1621 ttggttttct tagtgtattc tagaggaagt cccaatttct caaagagaag cacgcccaac
     1681 tgcttaggcg agttgacatt aaactcctca ccagccagct cgtaaatctc ttgagtcagt
     1741 ttttcaatga caagctcatt ttcagcctgc atctcaagca aggtctcttt cttgaccaca
     1801 atcccagcaa tttccatctt ggcaagaaca aaagccagag gttgctccat atcataaaga
     1861 agctctaatt gcccattttc gctgagtttt tcaagtaaaa taggctctgt ttctaccaaa
     1921 acagcaagtt tacaagctaa atgttccaag aatttctcac gttcaggaat ggccttttta
     1981 acacccttac cgtagaaagt ttcatcatca accaagtaag tctgaccata aagactagcg
     2041 atggtcgcaa tttcattgtc ctccacagtc gaaaggaggt atttagccaa acggatgtca
     2101 aaagcaggcg cctgcaaatc cacaccaaaa cgttgcaaaa gaactttaac cttcttaaag
     2161 tcataaactc tcagagatgt tttttctaag aaatccttga aaatcgggtc ttgcaacagc
     2221 tcaagcttgt ctgtggcata gagcttatcc ccacaagacc aggcaaatcc aaccaaatta
     2281 tccgtatggt aattctcacc aaaaagctca aagtggaaga tagactcttc actcagcata
     2341 tcttgactga tttggtcaac aatagtaaaa tccaaactct cagacacatc agctgacgac
     2401 acatttaaag cctgcttgag ctgtttgaag cccatctcat cgtaaaattt cccaagattt
     2461 tcaacatctg gaccactata gaccaagtcc tctaaaccaa tcgcaatcgg tgccttggta
     2521 tcaatggtcg ctagtgtttt agacaaaaag gcctgttcct tgtcattgat gagattttcc
     2581 ttcatcttag aagtcttcat tccatcaata ttttcataaa tcccctcaag cgaaccatgc
     2641 tccagcaaga gcttaatacc cgtcttttca ccgactttgg tcaccccagg gatattatcc
     2701 gacttatcac ccatgagcgc cttgagatcg ataaactgag ctggtgtgag gcccatttct
     2761 tccatgaggt aatctggcgt aaaggcctca aactcagcca cacctttctt ggaaatttca
     2821 accaccgtat gctcatccgt cagctgaatc aaatccttgt ccccactgac aatggtaata
     2881 tcaaaaccat cctgctctgc tagcttatcc agcgtcccaa tgatgtcatc cgcctcatac
     2941 tgagccagct catagtgacg aatccccata taatccagca actcacgaat gaaaggaaat
     3001 tgctcacgaa actcatcagg agtcttggcc cgaccaccct tatagtccgc atacatctct
     3061 gtccggaagg tcgtctttcc cgcatcaaaa gccaccaaaa tatgactcgg ctcaacccgc
     3121 tccaacaaat gactcaacat caactgaaaa ccataaatcg cattggtatg caaaccagcc
     3181 gcattcttaa aacggtccaa ctgctgatac agcgcaaaaa acgcccgaaa agctacagaa
     3241 gacccatcaa tcaataataa ttttttctta tccatacacc cattataaag gaaagaatca
     3301 aaaaatacca ttgggaagag ctagagcaag tatttttcaa actttttccg aataaataga
     3361 tagagccaga gaatttagta aacctagatt taaaaatgtg ctataatata ttgaatctat
     3421 aatagtacac cttgactgct aaaatatttc tataaattaa tttgactttc ctgatagagt
     3481 tattcacatc ttatttcaac tcactataga aggaggaaaa ggagggctgg gtggctaact
     3541 tcattataga actttcaaaa agatgaaaaa atagcgtcaa agaggctttt ttctctttaa
     3601 aacaggaaat ctcaaagaca atcttgcgac tatccaaact gtatgaatag cgagacataa
     3661 cttacttcgc taatactatc ttataaaaag atagaaatgt caagcaaaaa tgacaagtat
     3721 tttgataata aacttgccat cccatcaact ttctactata taaagtatga actcatagca
     3781 aggactcaaa ctcagccacg gtcatgccta attgctcact cgcaacctca ggtgttagaa
     3841 gaccttgacg tactagattt actaaaccta cttttaatcc ctcttcaagg ccttcttctc
     3901 gtccttgttc acgaccctct gcacgaccac gttcaatacc acgctccagt ccttgttcaa
     3961 ggccttcagc cctagcagtt tccaaggcat agtcctgtgc taacaagact tgttcttctc
     4021 gcatatgtag ttgactaaac attttcctgt cctcttcgga ccagctcttg tagtccagca
     4081 gttgatttgc ttgggtaatg gctcgttgcg gttgctgggt aaagggcttg ttgccgaaaa
     4141 actccaacca tggcttgcga accttgtctt tgctggtttc tctgtatttt ttaattccaa
     4201 gaatgccatc ttaaccagat ggttttcctg tccattgttg gtaatcgcca atacctcacc
     4261 tgttgtgtct tcgcgcatac taaagctatg aaaagccagg tcatctgaga aataattact
     4321 atccacgata gcaatggcgt aaacaggagc gatgtgtttg tagctctagt gagtatcacc
     4381 ttctcgctga cgaatttttt caagattttg attaacctga ctgcacaggt aagcccacaa
     4441 gcgattgatg aaaaattctg atgatggact tgaatctcaa taattacttg agtactgtta
     4501 tccaactccc ccaagacgtc tatactggta taaaaatcct gcaccgagta aggcatggag
     4561 agtaatacgt gaatattgct accctccaaa atggtcacat ttttggctgg caaatccagc
     4621 atatcgcgaa taaattgaca agtgatttct ggattgctaa agattttctt agctaccaag
     4681 tcattggttg ggctaatgcc cggatgacgt acagtcatat ttcttctctt tttattatat
     4741 cacagtttta aatctagctt tactagattc accgctacta tctatttatt cggaaaaaag
     4801 acgaaaaaac ctgagaatca tctcaggctt ggtcattaaa tttttttctc aatatcgaaa
     4861 agtggagaaa gtggtcgttt ttcatgaata cgtacgatag catcccctag gagatgagcg
     4921 attgaaatct gctcaatctt atcaatcaaa cgctcttctg gcagatagat ggtatccaaa
     4981 acaaccaatt tcttaatagc tgatttttgg atattgtccg tagcaggacc agaaagaact
     5041 gggtgcgtac agcttgcata gacttcaaca gcaccagctt ccgcaagagc atctgccgca
     5101 tgacaaatcg ttccagcggt atcaatcata tcatcaatca agatacaagt cttgccttca
     5161 accttaccga tgatgttcat aacttcacta gtattcatct tatcaacgct acgacgttta
     5221 tcaataatag cgatagatgt tttcaaaaat tctgccaact tacgagcacg agtcacccct
     5281 ccatggtctg ggctgacaac cacatagtca gaaccaacca taccacgacg ctcaaaataa
     5341 tctgcaatta gaggagcacc catcaaatga tccacaggaa tatcgaagaa tccttgaatt
     5401 tgcgcagcat gcaagtcgat ggtcaataaa cgatccactc cagctacttc aagcatattt
     5461 gcgacaagtt ttgaagtgat tggctcacgc gctctcgcct ttctatcctg acgtgcatac
     5521 ccatagtaag gcatgacaac attgacagat tctgcactcg cacgcttcaa agcatctacc
     5581 ataatcaaaa tttcaagcag attgtcattt acaggcgaac tagttgattg taggataaag
     5641 acgtgtttcc cacggattga ttcttcaatg ttgacctgaa tctctccatc tgaaaattgg
     5701 cgaacacttg atttccccaa ctctatccca atctcctgcg ccacacgttc tgccaattct
     5761 ttattagaag aaagggcaaa cagctttaaa tcagaaaaag acatgatttc ctccggtata
     5821 tatgtatcgc ttgtgctttt cacaagattt tccatctacc attgtagcgc tttttgcact
     5881 atttttcaat caaaaataaa agaagggcac catatttgta cccttgcatc attcttttga
     5941 aaaatattct aggtcatcaa ctcattgtgt ttctcaacaa agcaataagc atgataataa
     6001 ccatagagag caatagccgt aaccactgga atcgctaaag gcaactctgt ttccaactcc
     6061 acaaaaggag agttaaacaa taagaccctg tttcttgcca accttctgtc ctttataggc
     6121 tctgtaaagc aagtaaacac ctactacagc tagacctgaa aaagtccagt gagaggcaat
     6181 tccaagtaaa aacaaaaatt ttaattttcg cacaggaatc aaagccaaaa caaaaacaag
     6241 tggcaataat ttcaagggtt cttctaccaa aggagccaca atagcacttt caaaggcatt
     6301 taaaaatgta ctatctggga aaagaacccc cagtaaatca tggatataag tattagcaaa
     6361 actagacaac cagcctgaaa ggaacatccc tcccaataaa gacagaatca aaaccttctt
     6421 tggcaattcc cattttttcc caatacggaa gagaaaataa agagccggaa tcatgtaaaa
     6481 gagagctaga aagatagaaa ctcccattag tccatattcc gcacctgacc tcgaaccgtc
     6541 cgtatagtag atggtttcat actgtaaacc aatacatagc aataaaataa aaataaataa
     6601 aatactgctt ttcttcatac actttctttc taaatgaagt atttataatt ctacgactgt
     6661 catacttcct gtatcaacat tgtaaatggc accagagata atgacatcgt ctggtattag
     6721 gggagactcg ataagcagtt gcatatcctc gcgtacactc tcttctatat cttggaaggg
     6781 caagaagtcc tggtctgaca catctacacc taattcctct tttaaatact cctgaaaagg
     6841 ttcattttca aaggtctgag caccacagtc tgtatggtgc aataccacaa tctctcttgt
     6901 ccccatttgt tgctgggaaa taactagcga acgaatcatg tcttcagtca ctcgaccacc
     6961 tgcattccgc aagatatgag catccccaag tgccaagccc agagcttgcg caacgtgcag
     7021 acgagagtcc atacaggtca caatagctac tcttgttttg ggtttaagtg gcagatttaa
     7081 ctgcccatgt agggcaacat aagcctgatt ggcttgcata aactgttcaa aatacgacac
     7141 gattccctcc ttgaaaattt gatagtcaaa tatttctcct atcttatcat ttttaagaga
     7201 atttgtcacg gattatgcaa agaccttttt caagacttcc tgaatcgttg tcacgccaat
     7261 gacctgaatt tccttaggca gagtgattcc tgtcaaggaa ttcttaggta cataaatctt
     7321 agtaaagccc agtttagcag cttcgttgat gcgttgctca atacgattca cgcgccgaat
     7381 ctctcctgtc aagcccagtt ctccgacaaa acattcctga ggattagttg gcttgtcttt
     7441 gtagctcgaa gcaatagcaa ctgcaacagc caagtcaatc gcaggttcat ccaatttaac
     7501 accaccagca gatttgagat aggcatcctg attttgcaag agaagccctg cccgtttttc
     7561 caaaacagcc ataatcaagc tagcacggtt aaaatcaagt cctgtcgtag tacgcttggc
     7621 atttccaaac atggtcggtg ttaccaaagc ctgaacctcc gccaaaatcg gacgcgtccc
     7681 ttccatggtt acaacgatgg aggaaccagt cgccccatcc aaacgctctt ctaggaaaac
     7741 ttgactcgga ttgagtacct caaccaagcc gcccgactgc atctcaaaaa tcccaatctc
     7801 attagtggaa ccaaaacgat ttttgaccgc tctcaaaata cgaaaggtgt ggtgacgctc
     7861 cccttcaaag taaagcaccg tatccaccat atgctccaac atacgaggcc cagccaaggt
     7921 tccttctttg gtcacatgac ctacgataaa gatggcaatg ttattggtct tggccaactg
     7981 catgagttca gcggtcactt cacgcacctg agaaacagac ccctgcaccc ctgaaatctc
     8041 aggagacatg atggtctgga tggaatcaat aatgagaaag tctggctgga tacgctccac
     8101 ttctgcacga acactctgca tattggtctc tgcatagaga taaaactcac tatcaatatc
     8161 acctaagcgc tctgcacgta gtttaatctg ctgggcagac tcctccccac tgacatagag
     8221 aactgtcccc acttgggaca actgggttga gacttgtagg agaagagttg atttcccaat
     8281 cccaggatcc ccaccgatga ggacgagact tcctggtacc actccgcctc caagcacacg
     8341 gttgaattcc tccatctccg tcttggttcg attgacattg atggaagtca cctcagctag
     8401 tttcatgggc ttggttttct cacctgtcaa ggacacacgc gcattcttga cctcggcaac
     8461 ctcaacctct tccacaaaag aagaccaaga cccacagttg gggcaacgtc ccagatattt
     8521 aggggaatta tacccacaat tttgacatac aaatgtcgct tttttctttg cgatgacaaa
     8581 cctctttcta tatctctaac tcacactcaa tcacttggca aaaatcaatc ttctcatttg
     8641 gcacaaactg gcgcatgagc attcgatgag caacaactac cacagtctga tgttctcgat
     8701 acttagacat acattctaga aaccgagact tcatttccgt agctgtctca tattgaatag
     8761 gactattagg aagcaactcc cccttgtttt ctaaaaacag tcttctagct gtttcaaagt
     8821 tttctattcc tgttttatag acctgccatt catgtaataa aggctctact cttaaaggaa
     8881 gacccgtagc acagaccaca tacgaagccg tttctaaagc tcttgtgact gcagaagata
     8941 cgattatttc agctgacgag agtaaaggat ttttgctcaa tttctggact tgctgccgtc
     9001 ccatctcaga caagggtgcc aaatttatcc caaatcctat ataagaacgc tcctctaact
     9061 cactgtaatc cggctcccca tgacgtacaa agataatctt cattctagtg ccctgtcgat
     9121 ccaaatccac cagttcgaac gccatcagct gcatctccat ctgcaattaa gaaagtagca
     9181 aaaacagcct ggacaatacg ctccccaact tcaagaacaa cctcttggtc tgtgatattc
     9241 ttcatctgcg caaaaatatg cccttcattt ccaggatttc cataataatc cccatcaatg
     9301 accccaactg agttaattaa aaccaagccc ttcttacgag gatttgaaga acgatcatag
     9361 aggtagagaa cctcagtcgg ctgcatataa gccttaaccc ctgtcggaac caagacaatc
     9421 tctcctggcg caacaactgt acgcacagca acctttaagt cgtaaccagc cgcatgcgct
     9481 gtctcacgct tgggcaataa attttcatct gtaaaactcg aaaccaattc aaaaccacga
     9541 attttcataa ttttctcttt tctattatca tttattctag attattctat cttatttatt
     9601 cggaaaaagc acgaaaaaaa gagcacacaa ttcaaatcgc ttagggctgc tggattcctc
     9661 ccctgacccg cttcacgcag aactgttgct ccactattta ttatatcaca ttcctattca
     9721 ttttaaaagc aaaattattt tttccgtcta tttctaaaaa agtcctgcat gatagctgca
     9781 cattcatctt ccaaaattcc cgtttcaacc tctacacgat ggttaagacg ctcatctgtc
     9841 aagatatcgt acaaacttcc agtagcgcca aatttctggt ttttagcccc atagaccaca
     9901 tttggaatgc gggcaagccc aatcgcccca ctacacatga cacaaggttc aatggtcaca
     9961 aaaagtgtgc aatccagcaa gcgccagctc tcctcactca agttcgcatc ctctatagcc
    10021 ataatttccg catgcataac cgctcgctgt aattcctcac gcgcattatg cccacgacca
    10081 atgatttccc catctttgac aatcacacaa ccaattggaa tttcatcgtg ttcaagagca
    10141 atctcagcct ctctcaaagc ctccctcata aagacttctt tttcttcaag cgtataatac
    10201 atctcttttc tcttttccta cttatcgatt ttattattat atcatgaatc ccaacacaaa
    10261 aaaagccacc gaatgcggtg actctatagg gagattatta tgaaaaagaa aagtttagga
    10321 tatttgttac aacaagttag gaggtcttct tgtaactgtc tatagtatac ccgacctatc
    10381 ttaaacaaat cttaaaaatc tcttaggacc aaacactttc taaaatattt gtttgttcac
    10441 gaccaggacc tactgagaaa gtagaaatac gaacgccaac caattcactc acacgacgaa
    10501 catagttacg cgcattctca ggaagatctt ccaaattgcg agctccggta atatcttctg
    10561 accaacctgg caactcttca tagataggct tgcaacgttt caattgctca agactagctg
    10621 gatagtagtc aatacgttga ccgtcaagat cataggccac acaaattttc acagtatcca
    10681 agccgctcaa aacatcaata gagttcaaag aaaggttagt aataccagaa acacgacggc
    10741 tatgacgcat cacaactgag tcaaaccaac ctacacgacg tggacgacca gttgttgtac
    10801 catattcatg acccacttca cggatacgtt ctcccacttc atcaaacaac tcagttggga
    10861 aaggaccatc tcctacacga ctcgtataag ctttacatac acctacaacc ttgtcaatct
    10921 tgcttggacc gataccagaa ccaattgtca caccaccagc tacagggttt gatgacgtaa
    10981 caaatggata agtaccttga tcgatatcta gcataacacc ttgtgcacct tcaaaaagca
    11041 cacgtttgcc attatcaagc gcatcattca agataacaga tgtatctatc acgtatttct
    11101 tgatttgttg accatattcg taatattctt caaaaatatc atcgaaaaca atcgctttac
    11161 tgtcatacaa tttttcaaaa agacgattct tttcagcaag gttacgttct aaacgctcac
    11221 ggaaaatatc tttatctaaa agatctgcaa tacgaattcc aacacgagca gccttgtcca
    11281 tataagctgg accaattccc ttaattgtcg taccaatctt attgtcgccc ttagcttctt
    11341 cttgcaagcg atccaactcg atatgataag gcaaaataac atgcgcacga tcagaaatac
    11401 gcaagttatc agttgttaca ccttcctcat gaagatagct caactctttt acaagagatt
    11461 taggatttac aaccatacca ttcccaatga cagatatttt ttcagggaag aaaatcccag
    11521 atggaatcaa gtgcaactta aatttcttac cgtcaatcac aatcgtgtga ccagcattat
    11581 caccaccttg gtaacgtgca attacttctg cattcgctga aaggaagtct gtaatcttcc
    11641 ctttaccttc atcaccccat tgggtaccta caacaacaac tgaagtcata attttgtctg
    11701 agccctcagg ctcttccttt ctcacataca tggcaggact ctcacctgca attatatctt
    11761 acaatttatt ataataaaaa atcgcctttt tatcaagaag aaacaataga aagatttgct
    11821 atttccaact attaaaaaat gatttagaaa aattactagc tatttactat tatctttcca
    11881 taaaagagta aattagttcg gaaatttact aaaattacct caacaagaaa taaaaccccg
    11941 attcattacc aatttttcaa gatacaaacg ataagcaaca cgataatggt aaacgataaa
    12001 atccctacga caaccaatgc catatctcac taaataataa attaaaaatt taaaatgaac
    12061 atgttcccag tcaaaattat caccaaatgt aggaccatac tcttcttcaa tactatcata
    12121 gaaattagcc atctgctcat aaattttttg taacataatc aaatactcct tttctttttt
    12181 ataaacttat tctaacaaaa aattttacac attcactatc aattcctgaa ttgttaaaat
    12241 accagcctca acaagataaa aataggaaaa gttgacagaa tagaaacaaa tttgctacct
    12301 aaatttcaaa cgattaaagt tctaaaaaga ccgccttaaa acttttgggt aaatcctatt
    12361 agaactataa tatttttata taggtattat ggttctgatt ttctagtata aaaaaattca
    12421 aactagaatt cttcttataa aagtaaaagg ccgttttaag tgctatcatt gctcaaaaat
    12481 ggaggtcgct gagacttcta tcgtcaagaa gaatcatcaa attccttgta tcatcaacca
    12541 aaagattgct cagaagctaa ttgaaaagac ttctatgacc gacattgatc atcagttgtc
    12601 tatttcaatt tcaacttcaa ctgtcattcg caagatcaat gattttcact ttgagcatga
    12661 tttttcgcgt cttcctgaga ttatgtccta ggacgttgaa acagtccggg gagtgactgt
    12721 ttcaatcggg agatggagat gagctttatt gctcaagact ttgataagct caatatcata
    12781 actgttcttg agagcagaac acaagccatc atccgaaatc ccatgaatac aaggctatca
    12841 agcgatactg aaagctcatt caacaagata gtcagaaact gagtgataaa cgattttatc
    12901 gccctacttt tcgtatgcac ttgactaata aagaaattct agataaactt ttgagctatt
    12961 ccgaagactt gaaacaccac tataatctct atcagctctt gcttttccac ctctttttca
    13021 gactctgttt aaaaccttcc tcaaagataa agagaaaatc gtcaacgccc ttcaattacc
    13081 ttattccaac gccaaactgg aagccaccaa taatctcatc aaacttatca agcacaatgc
    13141 ctttggtttt aggaactttg aaaacttcaa aaaagaaagg acgaaatttg tcctttctag
    13201 attttcgctt tcttcaaccc actacagttg acaaagaacc gaaaaatgtc tcgcctctaa
    13261 tat
//
LOCUS       DBERXF010000052        12407 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.52, whole genome shotgun sequence.
ACCESSION   DBERXF010000052 DBERXF010000000
VERSION     DBERXF010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12407
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.52"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(133..1335)
                     /gene="rpsA"
                     /locus_tag="ACL8JK_001886"
     CDS             complement(133..1335)
                     /gene="rpsA"
                     /locus_tag="ACL8JK_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HGS1786707.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1497..1568)
                     /locus_tag="ACL8JK_001887"
     tRNA            complement(1497..1568)
                     /locus_tag="ACL8JK_001887"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1534..1536),aa:Gln,seq:ttg)
     gene            complement(1578..1658)
                     /locus_tag="ACL8JK_001888"
     tRNA            complement(1578..1658)
                     /locus_tag="ACL8JK_001888"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1622..1624),aa:Tyr,seq:gta)
     gene            complement(1708..1938)
                     /locus_tag="ACL8JK_001889"
     CDS             complement(1708..1938)
                     /locus_tag="ACL8JK_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGS1786708.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2106..2750)
                     /gene="pcp"
                     /locus_tag="ACL8JK_001890"
     CDS             complement(2106..2750)
                     /gene="pcp"
                     /locus_tag="ACL8JK_001890"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGS1786709.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2765..3688)
                     /locus_tag="ACL8JK_001891"
     CDS             complement(2765..3688)
                     /locus_tag="ACL8JK_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0859 family membrane protein"
                     /protein_id="HGS1786710.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3685..4374)
                     /locus_tag="ACL8JK_001892"
     CDS             complement(3685..4374)
                     /locus_tag="ACL8JK_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0858 family membrane protein"
                     /protein_id="HGS1786711.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4439..5143)
                     /locus_tag="ACL8JK_001893"
     CDS             complement(4439..5143)
                     /locus_tag="ACL8JK_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS1786712.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGDPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            complement(5199..6221)
                     /locus_tag="ACL8JK_001894"
     CDS             complement(5199..6221)
                     /locus_tag="ACL8JK_001894"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGS1786713.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6353..8824)
                     /gene="parC"
                     /locus_tag="ACL8JK_001895"
     CDS             complement(6353..8824)
                     /gene="parC"
                     /locus_tag="ACL8JK_001895"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGS1786714.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9025..9229)
                     /locus_tag="ACL8JK_001896"
                     /pseudo
     CDS             complement(9025..9229)
                     /locus_tag="ACL8JK_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014166.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            complement(9244..11187)
                     /gene="parE"
                     /locus_tag="ACL8JK_001897"
     CDS             complement(9244..11187)
                     /gene="parE"
                     /locus_tag="ACL8JK_001897"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGS1786715.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11323..11964
                     /gene="plsY"
                     /locus_tag="ACL8JK_001898"
     CDS             11323..11964
                     /gene="plsY"
                     /locus_tag="ACL8JK_001898"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGS1786716.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(12009..>12407)
                     /locus_tag="ACL8JK_001899"
     CDS             complement(12009..>12407)
                     /locus_tag="ACL8JK_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGS1786717.1"
                     /translation="SEIIAYNLSCSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQ
                     HDSYHQFLEGKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKTFKSLNQLEQAI
                     IDYIDYYNNKRIKVKLKGLIPVQYRTKSFG"
BASE COUNT         3572 a         2798 c         2186 g         3851 t
ORIGIN      
        1 ctgaatatca aaaaagaaag gacgaatttt gtcctttatc gagcttagct gacttcaacc
       61 cactacagtt gacaaagagc cagaaaaatc ccttgtttag taaacaaagg attttgtgaa
      121 ttttcaattt gattaaagtt cgatgtcacc aaacaaatca gccattgaaa atcctgtttg
      181 tgtttctgga agttcgaaat cacgcttttc ttgacgtctt ggacgacgtg gacgagcagc
      241 acgtttttct tctttttgtc cttcttcttg ggctggacgt tcttcaagag ctttaataga
      301 aagtgacacg cgttctgcat ctgcgttaac ttcaagaact ttaacttgaa cttcttgacc
      361 aactttaaga gcttcttttg gattttcaat ccgtttgtgt gaaatttgtg atacgtgaac
      421 aagtccatcg atacctggca atacttcaac aaatgcaccg aagtcagtca aacgtttaac
      481 tgttccttct actacatcac ctttagccaa tttttgctca acgccatccc atggtcctgg
      541 tactgttgct ttaagtgaaa gtgatacacg tccttcttct tcgttaagat caaggatttt
      601 cacttcaatt tcttcaccaa cagttacaac tgattttggt gatacgttac gttcatgtga
      661 caattcagtc aagtgaacca atccgtcaac accaccaagg tcgacgaaag cgccgaagct
      721 tgtgatacga gcaactttac cagttacaac atcaccaaca gccaatttac cgaatacttc
      781 agcgcgagct gctgcagtag ctgcttcaac aacttcacga cgtgaaagga tgaagcggtt
      841 ttctttagcg ttaacttctt tgattttagt atcaaattct tgacctacaa aacgctcagc
      901 attacgtacg aaacgagtat ccaacattga agctgggata aatccacgaa caccttcaaa
      961 ttctactgaa agtccacctt taacggcacg cgttccttta acagtaacaa cttcttcttc
     1021 gcgaccaaca agtttgtccc atgctttgcg agcttcaagg cgttttttag atacaaggta
     1081 tgtaactgta tcagtatctt taccaactac ttgacgaagt acaagaacat ccaatacttc
     1141 tcctacttta acaaagtcat tgatatctgc atcacgatcg tttgtcaatt cgcgaagagt
     1201 caagacacct tcaacaccag ttccagagat tgcaacgtta gcttgagtcg catcaactgt
     1261 caatacttca gcactaacaa catcaccagt ctcaacttga ctaacgctat ttagcaaatc
     1321 ttcaaattcg ttcatctaaa aaatcctcca acaatcaagt ttttcttaaa cttgacatac
     1381 ttataatttt tttcctaagc acccgcaagg acatgttcat atcattcacg tctttcaatt
     1441 ataaaaataa aataccctaa gatattttgc tttttatctt gattattacc taagaactgg
     1501 ggtagctgga ttcgaaccaa cgcatgaggg agtcaaagtc ccttgcctta ccgcttggct
     1561 ataccccatt aatgaaatgg agagagaggg attcgaaccc ccgaacccga aggagcggat
     1621 ttacagtccg ccgcgtttag cctcttcgct atctctccta caatcaacat ggactattat
     1681 atcatgaaaa tttcaaaaaa acaagactta ttttgctaaa ttataatttt caatcaaaat
     1741 ttccacagct ttttccaatt ttttataaaa actatcgaca ttcccattct ttataatggc
     1801 aaattgtccg tctaattcgg caatttctcc gataactttt ttaccgatag tcaatgtata
     1861 accttcaaaa ctgtctttac caacattaac tttggcatcc gctacttgaa tttcgatttt
     1921 tttatctttc ttgctcattt catacctctc ttcacttttt ctattttaca agaaaattct
     1981 aaaactagca agaaaaaact ctatatcagg cttctctgat atagagtttt atgtaaacaa
     2041 cctcaattga tttagcatag ttaatagtta gtaaacaagc ataattgact atccttttta
     2101 ggttatcagt gagtctcacc gcctactaac tgcaaatcct tatctttgta gtctacaata
     2161 gcttcaatag ctacctctat gcctcttaca atatcacata gactcattcc tgcagtattc
     2221 ggcttattta ctacttgttc catcatatat ggaatatgca tgaaacctgc tctcatatta
     2281 gggaattttt tatccactaa ataaagagct tggtacatca aatgattgca aacaaaggtt
     2341 cctgcactat tggatacaac tgccggaagt ccctgttttt tgatagcttg taccatcgct
     2401 ttgataggta aactactaaa ataggccgat gctccatcaa tacgaatcgg tgtatcaatt
     2461 ggttgattgc cttcgttatc aggtatgcga gcatcatctt gattaatagc cactcgttca
     2521 ggtgttaagc cggtcctgcc gcctgcttgt ccaatacaaa gtacagcatc tggttgatat
     2581 cgtaatattt ctgcctctaa aacttctgac gacttataaa aaaccgttgg aatttctacc
     2641 cagcgaactt cagccccatt aatctcagat ggtaataatt ttacagcctc caaagctgga
     2701 ttaatctttt cacctccaaa aggattaaaa cctgtaacca atattttcat tttattttcc
     2761 tttactaaaa tgcgagaaag tacattaaga atatgtgaat aacaatcatt actagagcaa
     2821 cacctgcttg agcctttata acgccattct gatctttcat atccatcaat gctgctggta
     2881 gagcgttaaa attagcagcc attggggtca ataaagtccc acaataacct gctgtcatgg
     2941 caagagcacc agccacaatt ggattagctc ccagagcaaa tacaaaggga actccaacac
     3001 ctgctgtaat aacggtgaat gctgcaaaag catttcccat aatcattgtg aatagaacca
     3061 ttccaagaac ataggccaaa actcctataa agcgactatc tgaaggaaca ataccgctaa
     3121 tcagatgaga gataacatca ccaacacctg ctacagtaaa aatagccccc aaagccccta
     3181 ataattgagg aacaatccca cttgttgaaa cttgctgagt cattcgatta ttttctgata
     3241 acagactctt agggtgacta ttggtaatca caagaacaga aattgtagca aacaaggcgg
     3301 caaggctaat cgaaatcttg ctaaattctg gaatcatttg cgctaagacc aacgcaagta
     3361 ttgccatcag cataactgga ataaaaattt tatttttcaa cctgttagat tcaatattgg
     3421 ctttcatttc atctaaggat ggcaaggttc cgatacggac ttgcttaaac aatgttaaca
     3481 gcgataatag gattacaata ataccaatac tcatatttgg catataggaa ccacctataa
     3541 acgtaataga caatagagtc caaaatgcag atgtcccaag tcgaactggg tttgttttat
     3601 ctttataact acaataggct gtatggagaa attgacaacc aatcacaata taggtcaact
     3661 ctaatagttg ctttgccaac tctgtcattt ttgttctcct cccctagtct tttttgatat
     3721 caatttttta tcaaataaat aattgtaaat ccccactaca ataagtgtta taacagcaac
     3781 aataatagat gtagaagcaa tccctgcata attgctttca tagcctaact gatctaatgt
     3841 tccccctatc aagaggactc ccccagcacc tacaaacgta ttttgagcaa agaaatttcc
     3901 aaaattttca ttcgcagccg cacgcgcttt tattgtctca tcttcaacct ctgttaactt
     3961 tctacctaat tgagactctg cagctgcttc tcccataggt tgaaccaaag gtctgacaaa
     4021 ctgagggtgt cctcctagac gaattgaaaa gaaaccagct aactctcgaa taaagaaata
     4081 aactgtatag aagtttccaa ctgtcagacc tttaatcttt cgaatcaaat cgattgatcg
     4141 ttgcttgagt ccaaaggttt ctgacagccc cacaagaggc aaggtaacca taaaaatcgt
     4201 gagcactcgc tgattgctaa attcttttcc caaaatctcc aaaaattcaa cgagagaaac
     4261 acctgaaact aaagctgtaa ccaaaccagc taagactact gttgcaattg tatcaaattt
     4321 taaaataaaa cccacaacaa tgattgctat tcctattaat ctaatccact ccatatcaaa
     4381 ctcctttata ttcaaaatga cagtattttt aaaattttat caagatcaat accattcctt
     4441 atttaatgtg tttttctagt tctttttggt atttgctatt ggattccaat ttttcttttt
     4501 gccatttttt aaaaacctcg ttatattctt ttgttgtaac aatatctttt tgcaatttca
     4561 ttcctttaaa gatatatgga tcccccttaa taccaacttg tgagtatggt tttgagaatg
     4621 gtactacgtt acttacaact ggagaaccac cagatgaagc tgttggcatc aataatgaac
     4681 tatctgtcga ccaagcttga gctttggcat atttttcata tctcttctct aggtcagtgg
     4741 tctcagaaac agcatcttct aacaatttct tatatttatc caaaccaggt ttagctacaa
     4801 catccttatc ttttcctttc gtaataccaa ggtgtttcat ggcagaacca gattttggat
     4861 ccataatatt caagtaagac gctggatctt gatagcttgg agcccatcct gtactattca
     4921 aatcatagtc tttttgagaa ggagcaacat tgccgtattt atcattttcc atcaaaccat
     4981 caataacatt tccaataacg tctgtcgtcg atgttcgagt cgctatactg tagcccaatg
     5041 atgctggatc tactgcatag acataagaaa atgttgtcgg tgcatctgct tctttatcag
     5101 tttttccaca agccactaaa atagctgacg tgctcaggac cactcctgct gttaagagcc
     5161 actttttcta tttcataaaa aatctccttt ggtttatttt aatctacttt tacaatccaa
     5221 ccttctggcg cttcaatatc gccaaactga atacccgtca attcattata taatttacgc
     5281 gtcacaggac ctacttctgt ttcactatag aatacatgga aatcatcacc atgttgaata
     5341 cctccaattg gagaaataac cgctgctgta ccacaggcac ctgcctctac aaaacggtca
     5401 agattatcaa ttggaacatc accctcaata ggagttaatc ccaagcgatg ttctgccaaa
     5461 taaagcaagg aatacttggt aatagatggc aagatagatg gactcaatgg tgttacaaat
     5521 tcattatcag ctgtaattcc aaagaagtta gctgatccga cttcttcaat ctttgtatga
     5581 gttgatgggt ccagatagat aacatctgag aaatgacgtg acttggccat ttttcctggt
     5641 aagagacttg cagcatagtt tccaccaacc ttagccgcac ctgtaccatt tggtgctgca
     5701 cggtcgtact catcctgaat caagaagttg gttgggacca aaccaccttt aaagtaattt
     5761 ccaactggca tagcaaagat ggtgaaaatg tactcttctg ccggttttac cccgataata
     5821 tctccgacac caatcaaaag agggcgaaga tataaggttc cacctgttcc gtatggtggt
     5881 acgtattctt cattcgcacg gacaactgct ttacaagctt ctacaaacat gtctgtcgga
     5941 acttgtggca tcaagagacg gtcacatgta cgttgcagac gtttagcatt ttcatcagga
     6001 cggaacagtt gaacactgcc atccttagta cgataagctt tcaaaccttc aaatgcttgt
     6061 tgtccatagt gaagacttgg agaagactct gaaatatgca aagttgcatc ctctgtaagc
     6121 tctccttgat cccattgtcc atttttgaaa tgagcaagat agcgataagg taatttcata
     6181 taggaaaaac cgaggttttc ccaatcaatc gttactgtca tattccactc cttattctaa
     6241 aaacctattt cttatattct acactatttt tctaaaatag caagtatatt ttgtaatttt
     6301 cagaaaattt ctccaataaa aaccagctct tagaactgat tcttcatttc acttatttat
     6361 cttcagtaac tacttcctga agataagcgt caaaaacttc ttcatctgaa atcgtgtcag
     6421 aaatgaagct tccattgcta gtgcgttctg acaagttcaa gtcttgcaat cggctttcat
     6481 agattgttcc tttattggat tggacaagca gagtttggtc gttcacatcc acttccgtac
     6541 tgaagaaatc gccaacaaat ccttgctctg caactgctcc tgccaagaag acacgatgcg
     6601 gtttgttttt caactcacgc aagacttgta atcctcgttt ggcacggctg gttgctagaa
     6661 tttcctcaat agaaacacgt ttcaagcttc cacgctgggt caagaggtag aaggacgaag
     6721 tattacagat aaagccagat tggaggacat catcttcttt caaattcata gccttgacac
     6781 ctgctgcctt agcaccgaca accggaacct cttcgatatt gaaacgcagg gcataaccat
     6841 tttgactaac caagacaaca tcatctagtt taatcggagc cactgctaca atctgatctg
     6901 tatcgtcttt gagcttagca tacttgacag acttagatct ataggtccgc catggagtga
     6961 attcttttcg ctctacccgt ttgatttgac caaggcgagt cactgcaaag taggttgtcg
     7021 catcgtcaaa ctgatccagt acttccacat aaaggatttc ttcattcgtt tcaaagtttg
     7081 tgatggtttg gctcagatgc tctccgatgt ccttccaacg aatatctgcc aactcatgga
     7141 ttggtctgta gatgacattt ccaagacttg tgaacatcaa gaggtgctgg gttgtcttgg
     7201 cagattgaac aaaaatcaaa cggtcatcat cacgcttgcc aatttcttcc aaggtggaag
     7261 ccgcaaagga acgtggactg gtacgcttga tgtaacctgc cttggtcacg ctgacgtagg
     7321 tatcttcctc agcgataaga ctagctgtat caatctcaat tgctttcgca gtgtcttcta
     7381 aagaactcaa acgaggagtt gcaaatttct tcttgacctc acgaagttct ttcttcatga
     7441 gattgtacat agtcctttca tcaccgataa tagccgccag catagcaatc ttctcacgaa
     7501 gctctgcttc ttcttcctgc aagacaacca catcggtatt ggtcaaacgg tacagttgca
     7561 aagttacgat agcctcagcc tgttcttccg taaaatcata gctaactttg aggttttcct
     7621 tggcgtccgc cttattctca gaagcacgga taagagcaat gacttcatcc aaaatcgaaa
     7681 tcacacgaat caaaccttcg acgatatgga gacgtttctc agccttttct ttgtcaaagc
     7741 gtgaacgcgc caaaatcact tctcgacggt gagcgatgta gctagacagg attggaacaa
     7801 tcccaacctg acgaggtgtg aaattgtcaa tcgccaccat attaaagttg tagttgattt
     7861 gtaggtcggt gtacttaaat aagtagttga gaacaagctc agtattagcg tctttcttaa
     7921 gttcgatagc gatacgaaga ccatcacggt cagactcatc acgaacctca gcaatcccag
     7981 ctaccttgtt attaacacga acatcatcga ttttcttgac tagattggcc ttattgattt
     8041 cataaggaat ctcagtaata acgatttgtt ccttaccacc ttttagcttt tcaatttcag
     8101 tcttggaacg aacaaccacg cgccctttcc cagtctcata agctttcttg atttcatcac
     8161 gaccctgaat aatagcccct gtagggaagt ctggtccagg caagaattcc atgagtttat
     8221 caatctttgc agttgggtgg tcaatcatgt aaactgcagc atctatgacc tcagctaaat
     8281 tatggggagg aatgtctgtg gcataaccag ccgaaatccc agtcgaacca ttgaccaaga
     8341 ggtttggaaa ggctgctggc aagaccgttg gttctttctc cgtatcgtca aagttccatg
     8401 caaaaggaac tgtatttttc tcgatatcct gaagaaggta acctgcaatt tcagacaaac
     8461 gtgcctcagt ataacgcata gccgcaggag gatctccgtc catagaaccg ttattaccgt
     8521 gcatttcaac tagaatctca cgatttttcc agttctgtga catacgaacc atggcatcat
     8581 agatagaaga atccccgtgt gggtggaaat tccccatgat gttcccgact gacttggccg
     8641 acttacggta gctcttgtca aaagtattgc tatccttatt catagaataa agaatacggc
     8701 gctgaaccgg cttcaaccca tcacgaatat ctggcaaagc ccggtcttga ataatgtact
     8761 tggagtagcg accaaagcgc tctcccatga tgtcctccag ggacatgttt tgaatgttag
     8821 acataagata caaagcccat aaaataccaa gtgaaaatag aaaattcttg aagtaagcaa
     8881 actcacaaga gaatttatct ttttcacaca gtatctaggg cgtgttcaac tcctttcaaa
     8941 gaatgtagag taggttttta tgcagtaaaa gatattttac gggaattcct cccgtgttca
     9001 gttacgataa gtaaccaaac tatcctgttt gtatttttca atatgaaaat ctggttttcc
     9061 aaaattagtc ttagtttgtg tcttaaccgc tcccttaagc gcctctttga gataagcact
     9121 catagcagat tcttcattaa taatcctgca attttttcaa accaagattt tcaaactgct
     9181 ttttcacata gtcattcaca tccgactcta atttccagtt tactaacata ttattttctt
     9241 tcattaaaac actgtcgctt cttctagcgt aaacttgaca ttatcttcaa tccatttacg
     9301 gcgtggttct accttatctc ccatgagaac attgacgcgg cgttcggcgc gcgctaaatc
     9361 ttcaattgtg acacggatga gggtacgtgt ttctgggttc atggttgttt cccagagctg
     9421 gtccgcattc atctcaccaa gtcctttgta tcgttggagg gtagcgcctt taccgaactg
     9481 tttacggagt tcttctagtt ctccgtccgt ccaagcgtag gccacttctt ctttcttgcc
     9541 tttacctttg gacatcttgt aaagaggtgg gagggcaata tagacatgac ctgcctcgac
     9601 tagcggacgc atgtaacggt agaaaaatgt caagagcaag gtctggatat gggcaccgtc
     9661 ggtatccgca tcggtcatga taatgatctt atcatagttg gcatcttcaa tagagaagtc
     9721 tgctccaaca cccgcaccaa tggtataaat catggtattg atctcttcat ttttgaggat
     9781 atccgccatc ttggccttgg ctgtattgat aaccttacca cgaagaggta gaatagcctg
     9841 gaacttgcgg tcacgacctt gtttggcaga accaccggca gagtccccct caactagata
     9901 gagttcattc ttagcaggat tcttagattg ggctggggtc aatttcccag acaacaagcc
     9961 cttatctttc ttgtttttct tcccatttcg gctctcatca cgcgccttac gtgctgcttc
    10021 acgagcatca cgggccttga tagccttgcg gatgaggtta gaagctaatt ccccattttc
    10081 cataaggaaa aaggtcaact tatcagccac tattccatcc acaactgggc gagctagggg
    10141 gcttcctagt ttatccttgg tctgtccttc aaactgcaag tgttcttcag gaactaagat
    10201 agaaagaacg gccgctagtc cctcacgata gtctgaacct tcaaggtttt tatctttttc
    10261 cttgagaaga cctgttttac gtgcatagtc attcatgacc ttggtaatgg cagacttgag
    10321 tcctgtctcg tgcgttccac cgtccttggt gcgaacgtta ttgacaaagg atagaatgtt
    10381 atctgagaat ccgtcattgt actggagggc tacttccact tgaaaaccat tgtcttcccc
    10441 ttcaaagtaa agaactggcg tcaagatttc cttatcttcg ttgagataag aaacaaaatc
    10501 ttgtactcca ttctcatagt ggaactcaat cgcttcatct gttcgcttgt ccgttaaaga
    10561 caaggtcaca tttttcaaga gaaaggctga ttcattaagg cgctctgaaa tggtattgta
    10621 cttgaaatct gtcgtagaaa agatagtcgc gtcaggcata aaagtaactt tggtgcctgt
    10681 tttagacttg ggtgctgtac cgattttctt caaagtcgtg acaggttttc caccattttc
    10741 gaaacgttgc ttgtaaactg cgccatcacg ggtaatttca acttctaacc agctagaaag
    10801 ggcgttaaca acggaagaac ccactccgtg aagtccacct gatgtcttat agccaccttg
    10861 accgaatttc cctccggcat gaagaatggt aaagataacc tcaacagttg gaattcccat
    10921 agcgtgcata cctgtcggca tcccacgtcc atggtcttga accgttagac taccgtcttt
    10981 attgatggtt acatcgatac gatcaccaaa cccagacaag gcttcatcga ctgcattatc
    11041 aacgatttcc caaactaggt gatgaagacc agcgccatcg gtcgatccaa tatacatccc
    11101 tggacgtttt cggaccgcat ccaacccttc tagcacctga atagcatcat cattataatt
    11161 gttaatattg atttcctttt ttgacacaag gaacctccta ttcgttcatc tttactattc
    11221 tacaggtttt ccaaggattt tgcaaaattt ttctttctcc gatgtgacaa ttttagcaga
    11281 gattctctgc ttttctttcc caattcatga tataatagga gtatgattac aatagtttta
    11341 ttaatcctag cctatctgct gggttcgatt ccatctggtc tctggattgg acaagtattc
    11401 tttcaaatca atctacgcga gcatggttct ggtaacactg gaacgaccaa taccttccgc
    11461 attttaggta agaaagctgg catggcaacc tttgtgattg actttttcaa aggaacccta
    11521 gcaacgctgc ttccgattat ttttcatcta caaggcgttt ctcctctcat ctttggactt
    11581 ttggctgtta tcggccatac cttccctatc tttgcaggat ttaaaggtgg taaggctgtc
    11641 gcaaccagtg ctggagtaat tttcggattt gcgcctatct tctgtctcta ccttgcgatt
    11701 atcttctttg gagctctcta tcttggcagt atgatttcac tgtctagtgt cacagcatcg
    11761 atcgcggctg ttatcggggt tctgctcttt ccactttttg gttttatcct gagtaactat
    11821 gactctctct tcatcgctat tatcttagca cttgctagtt tgattatcat tcgtcataag
    11881 gacaatatag ctcgtatcaa aaataaaact gaaaatttgg tcccttgggg attgaactta
    11941 acccatcaag atcctaaaaa ataaaatgcc agttctgtga actgcacccc aaaagttaga
    12001 caattaattt atccaaagga tttagttctg tattgcacag ggataagtcc ttttagtttt
    12061 accttaattc gtttattgtt gtagtaatca atatagtcta taatagcttg ttccaattga
    12121 ttaagtgatt taaatgtttt ctcataaccg taaaacattt ccgatttcag aatcccaaag
    12181 aaggactcca tcataccatt gtctgggctg ttacccttac gtgacatgga tgcttgaatt
    12241 cccttaccct caagaaactg atgataagaa tcgtgttgat attgccagcc ttggtcacta
    12301 tggagaatcg tattctcgta gtgcttctct gtgaatgcct gttccaacat tgtttgtact
    12361 tgttctaaat taggcgaaca agaaagatta taggcgataa tttcgct
//
LOCUS       DBERXF010000053        11900 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.53, whole genome shotgun sequence.
ACCESSION   DBERXF010000053 DBERXF010000000
VERSION     DBERXF010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11900
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.53"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(38..1174)
                     /gene="dnaJ"
                     /locus_tag="ACL8JK_001900"
     CDS             complement(38..1174)
                     /gene="dnaJ"
                     /locus_tag="ACL8JK_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGS1786718.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGDGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGQGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(1576..1932)
                     /locus_tag="ACL8JK_001901"
     CDS             complement(1576..1932)
                     /locus_tag="ACL8JK_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HGS1786719.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(1934..3757)
                     /gene="dnaK"
                     /locus_tag="ACL8JK_001902"
     CDS             complement(1934..3757)
                     /gene="dnaK"
                     /locus_tag="ACL8JK_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGS1786720.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(4237..4761)
                     /gene="grpE"
                     /locus_tag="ACL8JK_001903"
     CDS             complement(4237..4761)
                     /gene="grpE"
                     /locus_tag="ACL8JK_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGS1786721.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(4788..5822)
                     /gene="hrcA"
                     /locus_tag="ACL8JK_001904"
     CDS             complement(4788..5822)
                     /gene="hrcA"
                     /locus_tag="ACL8JK_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGS1786722.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKTLQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKRIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(5986..6495)
                     /locus_tag="ACL8JK_001905"
     CDS             complement(5986..6495)
                     /locus_tag="ACL8JK_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HGS1786723.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFEQ
                     GQPDDVIYRIYDSRFLKEHKRELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCMSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            7104..9437
                     /gene="hsdR"
                     /locus_tag="ACL8JK_001906"
     CDS             7104..9437
                     /gene="hsdR"
                     /locus_tag="ACL8JK_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HGS1786724.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKEDSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            9450..10913
                     /locus_tag="ACL8JK_001907"
     CDS             9450..10913
                     /locus_tag="ACL8JK_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGS1786725.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            10913..>11900
                     /locus_tag="ACL8JK_001908"
     CDS             10913..>11900
                     /locus_tag="ACL8JK_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1786726.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQ"
BASE COUNT         3679 a         2298 c         2298 g         3625 t
ORIGIN      
        1 cgacgctgac gtggtttgaa gagattttca aagagtatta ttctccatca aaggcatctt
       61 taatatgatc aaagaagcct tttttctttg gatttacttt caagtcacca gcagccgcga
      121 attctttcaa ggctactttt tggcggtcgt tcaagcctgt cggtgttacg acattaacag
      181 taacgtattg gtcaccaact gcaccgccac gaaggctcgg tgccccctta ctacgtaggc
      241 ggaatttctt accagtctga gttccctctg gaataaccaa ttcaacatca ccgtgaacag
      301 ttggaatatc tactgtatca ccaagagccg cttggacaaa gttgaggttg agattgtaga
      361 agatagtcgt tccttcacgt tcaaacttgt cgctagcttc cacagaaact actacataca
      421 agtcaccata aggtccaccg ttaaagcctg cttcaccttg accagcgagg cgaatttgtt
      481 gacctgtttc cacaccagca gggattttca catgtacgct atgagcttgt ttctcatgac
      541 ctgttccatg acaggttgta catggatatt tgatttcttt tccttggccg tgacagacat
      601 cacaggttac ttggcgacgc atcataccaa gaggagtctg cgtatcgacg ttaatgacac
      661 cagcgccatg acagcgtcca caagtgactg gacttgtccc tggcttagca ccagagccat
      721 tacatgtacg acagccagct tcacgatgat acttaacttc cttctcagtt ccgaagatag
      781 cttcttcaaa ggtcaaattg acacgatact ggagatcatc tccttggcga ggagcgtttg
      841 gattgcgcga agaaccgcct ccgccgaaga aacttgagaa aatatcctca aaaccaccga
      901 agccacctgc cccattgaaa ccgccgaaac caccatctcc accaaaacca ccattggcgc
      961 ctgcagcacc atactggtca taggcagcac gtttttggtc gtcactcaaa gtctcatagg
     1021 cttcttgaac ttccttgtac ttgtcctcag caccaggctc cttgttgata tctgggtgat
     1081 attttttgga aagcttacga taagcctttt tgatttcgtc tgccgaagcg tttttggata
     1141 cccccagacg atcataaaat tcagtattgt tcataattca agatacaaag ggcgtcaaac
     1201 ggacacagcc atctaggagt tttgacgacg gacgcttatg tcctagaaaa aactatcttt
     1261 ttggcacagt ccgtagcccg tgttcagtta cgaacaccct tattcctttc tattgatgtt
     1321 ctgaatcgaa ccaccattta ggtcggattc aattcctttc ttttatattt agtaagaaat
     1381 tctgaaaccc gtgttcagtt acgaacactc tttgttcctt tctattgatg agacaaaacc
     1441 caaacaaatg agattccgtc cctttttatc gaaaaacaga ggctgggttg caacctctgc
     1501 aaataagtaa attaacttta ttttgatttt aaatatccta taagtacaga aatatttata
     1561 tatttttgtc tcttcttagt atttgcctat ataattccaa ttgatcataa gaaatacaac
     1621 tactgtccaa atcataccaa ttatgaacgg tattacaaat ttatatgttt gtatttctaa
     1681 tgatatcata gctgatacca tcgccgatac aaatgcagac aacaatactg aagtaacaaa
     1741 attccttacc gcttcatcat ttttgacaca actatcatgc tcagctaata taatttctct
     1801 atatatagtc aaacattcta ctggaatatt atctataaaa ccttttgctg cttcatagtt
     1861 gtcagcttga ttacaaaaat cattataaac ttttcgtgta ttttttagat actcatcatc
     1921 caatacactc atcttatttt tccgtaaact ctccgtctac gacgtcatcg cctgcgtttc
     1981 ctgttgcttg tgcgccttct gctccttctt gagcttgttg cgctgctgcg gcttgttcgt
     2041 agagtttcac agcaaggcct tgagcttttt cgttcaacgc ttcaagtttc gctttcatgt
     2101 cgtccaagtt gttgtcttct tgagctttct taaggtcatc aagggcagct tgggcagcgt
     2161 cacgttctgc gtcgaagcct ttaccttcag tttccttgat tgtcttttca gtcgcaaaga
     2221 ttgcttggtc tacttcatta cgaaggtcta cttcttcttt acgtttctta tcagcttcag
     2281 cgtttgcttc tgcatctttc atcatgcggt cgatttcttc gtcagtcaaa cctgagttcg
     2341 attggatgac aatagtttgt tctttttgag ttccaaggtc tttggcctta acagacacga
     2401 taccgttctt gtcgatgtca aatgttactt cgatttgagg aattccacga ggtgcagctg
     2461 ggatatcagt caattggaag cgtccaagag tcttgttatc tgctgccatt gggcgttcac
     2521 cttgaagaac gtggatatca acggctggtt ggttgtctgc tgctgttgag aagacttgtg
     2581 atttagatgt tgggattgta gtgttgcgat cgataagttt tgtaaatact ccacccattg
     2641 tttcgatacc aagtgacaat ggcgttacat caagaaggac aacgtccttg acatcaccag
     2701 taatcacacc accttggata gccgcaccca tagcaactac ttcatcaggg tttactgatt
     2761 tgtttggttc tttaccagtt tcagctttaa cagcttcaac aacggcaggg atacgagttg
     2821 aaccaccaac aaggataact tcgtcgattt ctgacaagct caaacctgca tctgaaaggg
     2881 cttgacgaac tggaactttt gtacgttcaa caaggtcacg agtcaaatcg tcaaatttcg
     2941 cacgagtcaa agtcatttcc aagtgaagag gtccagcctc acctgcagtg ataaatggca
     3001 agctgatttg tgttgaagtt acaccagaaa ggtctttctt cgctttttca gccgcatctt
     3061 tcaaacgttg cattgccatc ttgtcagtag acaagtcgat accgttttct ttcttgaatt
     3121 ctgctaccaa gtggtcaatg attttttggt caaagtcgtc accaccaagt ttgttgtccc
     3181 ctgcagttga caatacgtcg aagacaccgt cacccaattc aaggatagag acgtcgaatg
     3241 taccaccacc aaggtcaaat accaagattt tttcttcttt gtcagtcttg tccaaaccat
     3301 aagcaagagc tgctgcagtt ggttcgttaa caatacgttc tacttcaaga ccagcaattt
     3361 taccagcgtc ttttgttgct tgacgttgag cgtcgttgaa gtaagccgga actgtgataa
     3421 cagctttggt tactttctca ccaaggtagt cttcagcgta gcctttcaag tattgaagga
     3481 tcatagctga gatttcttgt ggagtgtatt cttttccatt tgcagaaact ttttcagaag
     3541 ttcccatctt agatttgata gagataactg tatctgggtt tgtaactgct tgacgttttg
     3601 cagcatcacc aacgatgatt tctccgtttt tgaatgagac tacagatgga gttgtgcggt
     3661 ttccttctgg gtttgcgatg attttgcttt cagttccttc aagaactgca actgctgagt
     3721 ttgttgtacc taagtcaata ccgataattt tagacatgtg tttttctcct tgttagttaa
     3781 ttttctattt ttctttttga tactcttctt aagtggcgac gccgtcagag cttgacttcg
     3841 tcaatctctt tgactaaact ttgagcctaa ggtctcaaaa tttgcgcaaa tagcaccacg
     3901 gcgaagagta tcgtctttgg ttcgcttcgc tcactattac aaagccaaac atattttatc
     3961 tttcttcata gtttattgtc gtttcggaca agttttctat tatgtaaatt gcgacacgag
     4021 gagtcgaaat cgattttatt tcgacgacga gttagtaagg aagctaggca aacgccatag
     4081 cgattgccgt tttctgacga gttgctttag ctaccgtcag aattgccgaa tcgaacacgc
     4141 cctaagctct gagtaaaaaa gatagatttt cttgtgttca tcgaacactt cgtcaatctc
     4201 ctatttttac tgcgagcttt ttacgagctt tgtatcttag ttatacacca ctaccattgc
     4261 tgggcgtagg atgcggtcat ggagtttgta gcctttttga aagacttggg cgatggtatc
     4321 tactgggtgt tcatcgtctg ctgggagagt ttggatggcc atatggtagt tatggtcaaa
     4381 ttcgccatct gctgcgattt cttcaattcc ttcttctttc aaagcgtgaa tcaagctttc
     4441 ttgcaccatc gccaagccct tcttcacatc atctgtcaaa ccttcaactg caagtgcacg
     4501 ctcaaggttg tcaagagatg gtaagattgc ttttgccaag tcctggctac gataacgttg
     4561 caagttttga cgttcttcat tggcacggcg ttggatattt tgcatttctg catgagcgcg
     4621 aagatatttg ttttcgaact catctgcacg ttcatttgcc aagtccaact cagacttttc
     4681 aggagttgtt tcttcagctg tttccacaac ttcctcttct tgaacttctt ctacttcttc
     4741 attttttata tcttgggcca tgttcgcctc ctttaatgat ttcaatctta atgtacttcg
     4801 taatgattac tgctgaggta gcggtaaaaa tctgtcaact tcatggtcaa aacacggttg
     4861 accacattga cttgattgat tagctgttgg taatccagat taactggacc gataatggct
     4921 agaattccaa ctccccgata aggaatgagg aacttactac taatcaccgc taggtcagct
     4981 aaacaggact cttgaccgtc tgcaacacga acattttgca tctgatcctc acgcaacccc
     5041 tcacgaatct ccaaggccac cttttgcggt tggtcaaaga actgataggc tgctagattg
     5101 gcaaaattca agagattgac cttgcccgcc atcacaatgt tttcgttgaa catttcctta
     5161 aagatgtgtt caaagagatc gatgacatta tccgttgttg taaagtaacg ctggataatc
     5221 tgcggaatct ccgtccgaat cttgtagtga atatctaaaa cggtgtgacc gaggaaacgt
     5281 tcctgaatga ttctcttcag tttcagcaaa tcctcctgca agaagttcct tggaatcaga
     5341 aactgactag taaccgttcg cgactcgtct agggtaaata ccgccaaggc tgtatgttgc
     5401 cccaaaacaa cgatatcaaa ggctgtcaac cgttgcctgc tcggctcaac atccagtgcc
     5461 actaccgtac agccactcag gtctgttagc aagttagcag cctcttgcag aatatcctcc
     5521 aatttgaaga attcctgatc aaaggctttg acaatctcat atacctcatt ttcagccagt
     5581 cggtcaaaat ccagtgagtg tttcacatag tactgaaaac cagcaacact tggcatccga
     5641 ccgcttgaag tatgagcctt ctcaagcaac ccttgttttt ctagttccgc catgtcatta
     5701 cgaatggttg cactgctaga gttaatagac tcttgcaagg tttttgatcc gacaggttcg
     5761 tgcgttttgg taaagatgtc aataatcaga tttaaaatat cctgctgacg ctctgtaacc
     5821 atctcatcac tcctctctgt ctgatcaatt agcactcaat gcatccaagt gctaactcat
     5881 gattctatta tacaccctta gaagagaatg tcaagacaaa aactcaaaaa attagcactc
     5941 ttttatcaag agtgctaaaa atcaatctga agacctagaa ccttgctatt catctactcg
     6001 gtatttcctt tttagtctga aataaccatg aattagataa gaaatcagaa aagcatataa
     6061 aacaaaaata agaaagaaag acatagaaag atcctctcta aacaaactca tacaaacaac
     6121 aagaccacct aagaaagtag ctgtacagga acgaagtcta gatcgcataa cttcccattt
     6181 gagcccctta ctcatataga cttgatcctc tggaagtaaa tcagaagacg atttacgaag
     6241 aatcgaacaa gaacctgctc ctatcaattc ccaacctcta tctctaaaat cttgcagttc
     6301 acgcttatgc tctttaagaa atctagaatc atagatacga tagataacat cgtccggttg
     6361 accttgctca aaatagaaca aaccaaaacg actcgttcta tacctccaac ctttcaaatg
     6421 catctcatgt aaatattctt ctttcttgtc caaatcaaca atggtgaaaa tccgaaattc
     6481 tactctgcta ttcattgtct taccccaaaa ttagaaaaca tgcctggcgt tatttagtta
     6541 gataattctt tccacttttg actcaatctc caaaaaatat aagaaatctg aatcgcaaaa
     6601 actatcaata aaacccaatc tattatgaaa atcaaaaaca ctttccaact gaaagaacta
     6661 cctccagtaa caaactttga gaaaaacggt agtagagcta aaaagagaag taaaatagga
     6721 agcatccgca ttgttaaaat ccgtttggca taaaaaaatc ttcatttaaa cgaaaatatt
     6781 atagcaaaat ttacgccagt ttttgaacgg ctgatgtaga tattttatac tttcaaaatg
     6841 tttaaatgtg attatttatt tttgaaaaat agctcaccag cccgactgaa agtgcttata
     6901 gaatgataat aagtcgcctg ccgaaaacag cggaaaatag cggtgttatg cggagataat
     6961 ctgacgcgat gcgaaagtat attgcatact tattttcaac aatttagcag agtattttta
     7021 taagtgtgat ataatagaag tataatttgt tctgatagtt tattttatgg agaagtagat
     7081 ttttagaatg cggagggttc aatatggttg agtttataaa gtctaagaaa gaaatgagtg
     7141 aggaggatat taaagcaaat ttcatcactc ctgctattgt atccaaagga tggaaaaatg
     7201 gtgagcatat cgcttacgaa gaatacttca ctgatggtcg aattgaggtt agaggagata
     7261 aggctcgtcg taaagaagga aaaaaatcag actattcact gtattaccaa tttggaactc
     7321 gaattgcaat tgttgaggca aaggataata aacacagcgt tcgagcagga ttacaacaag
     7381 ctattgaata tggagagatt ttagatgttc catttgttta ttcttcgaat ggtgatggct
     7441 ttattgaaca cgaccgtatc acgagagaag aacgtgagct ggagttagac gaattcccta
     7501 ctcgtgaaga attattttct cgtatgacga aggaaaaagg attgacgtac gaaattacag
     7561 aagctatctc aactccatac tatacagacg ccttctcaat gaaaacgcca cgctattatc
     7621 agcaaatagc tatcaaccgt actattgaaa cagttgccag aggacaaaaa cgagtaatgt
     7681 ttgtgatggc aacaggaacg gggaaaacgt tcatggcttt tcaaattatt catcgccttc
     7741 gaaaagctgg tttggctaaa cgagttttat tcttagcaga tagaaacatc ttagtagacc
     7801 aaacgatggc tgaagacttt aagccattcg aaaaggtaat gacgaaaatt acaccaaaac
     7861 ttttgactgc tcctgaaaag ttaaattctt ttgaaattta tctagggctt tatcagcaac
     7921 taactggtga agatggaact gaaacacatt atcaaaaatt tgacaaagac ttctttgatt
     7981 taatcgtaat tgatgaagcg caccgtggtt cagctaagga agacagtaac tggcgtaaga
     8041 taattgatta tttcagttct gcgacacaga ttgggatgac cgctactcct aaagaaacca
     8101 agaatgcttc caatacggaa tactttggtg agccaatcta tacttatagt ttaaaacagg
     8161 gaatcgagga tggttttttg gctccatatc gtgttatgag ggttaattta gatgtggatg
     8221 tggatggtta tcgtccagaa actggaaaag ttgatgctaa cggacaatta atagaagata
     8281 ggtactacgg caggaaagat tttgataaaa ccattgtcat tgatgataga acgcaaagag
     8341 ttgccaagtt tgtttctgat tatatgaagc aaaacaatgc acgatttgat aaaacaattg
     8401 ttttttgtgt tgatattgac catgccgagc gaatgcgtgc tgcacttgta aaagagaatc
     8461 tagacttagt ccaagaagac tatcgttatg tcatgcaagt aactggtgac aacgctgaag
     8521 gaaaagctca actggataac tttatggatg tcaattctaa ttttcccgct attgtaacaa
     8581 cgtctaaatt attaacgaca ggagttaatg ctaaaacatg tcgtttgatt gttttagact
     8641 ctaatatcca atccatgact gaatttaaac aaattattgg tcgtggcaca cgtctttatc
     8701 ctcaaaaggg gaaagaattt tttacgatta ttgattttcg aaatgttacc aatttgtttg
     8761 ctgaccctga ttttgatggt gatccagtga aggtgctaga aacaggtgcg aaaacagtca
     8821 gtggttctac gcccggtttc gtagatgagg aaggtgaccc agtagaaaaa tatatcgtta
     8881 cagacaagca ggttaccatt cttaattcta ctgttcaagt attggatgaa aacgggaaac
     8941 tgattaccga aagcctgacc gactacactc gaaagaatat cttaggtagc tacgccactt
     9001 tgaacgattt tatcacagtt tggcatacgg cagataagaa gaagcttatc ttagacgaac
     9061 tttataaaaa aggagtttat ctagatgcta ttcgagagtc ggagggaata tcagaacaag
     9121 aaatcgatga ttttgattta ctcctaaaac ttgcctatgg tcaaaaagaa ttaaccaaaa
     9181 cggaacgtat caataaactc aaacaaagcg gatatttata taaatatagt gaggaagcgc
     9241 gtgctgtttt ggaaatttta ctgaacaaat acatggataa aggtattgga gaactcgaaa
     9301 gcattgaaac attaaaactt ccagaatttc agatatatgg tggaaccttc aaaatcatca
     9361 atacttattt tggagataaa aaacgatatt tacaagcaat taaagaattg gagcaagagc
     9421 tatttacagt agcttaatga aaggaaagta tgtcaattac atcatttgta aaaagaattc
     9481 aagatatcac tcgaaacgat gctggtgtta atggtgatgc tcaacgtatt gagcaaatgt
     9541 cttggttatt attcttaaaa atttatgata gccgtgaaat ggtttgggaa ttagaagaag
     9601 acgagtatga gtcaattatc ccagaggaat taaaatggcg aaattgggct catgctcaaa
     9661 atggggaacg ggtattgaca ggcgatgaat tacttgattt tgtcaataac aagttattca
     9721 aagagttgaa agagcttgaa ataacttcaa atatgcctat tcgaaaaacg attgttaaat
     9781 cagcttttga agatgcgaac aactatatga aaaatggcgt cttgttacgc caagtcatca
     9841 atgttattga tgaagttgat ttcaatagcc ctgaagatcg tcattcgttt aatgatattt
     9901 acgaaaaaat tcttaaagat attcaaaatg ctgggaactc aggagaattt tatacgccac
     9961 gtgcagcgac tgattttatt gccgaagttc ttgacccaaa acttggagaa tcaatggcag
    10021 accttgcttg cggaacagga ggcttcttga cttcgactct gaaccgttta agtagtcaac
    10081 gtaaaactag tgaagatacc aaaaaatata atacagctgt ttttggtatt gaaaagaaag
    10141 catttcctca tcttttagca gttacaaatc tgtttcttca cgaaattgat gaccctaaaa
    10201 ttgttcatgg aaatactttg gagaaaaatg ttcgtgaata tacggatgat gaaaaatttg
    10261 acattattat gatgaatcca ccttttggag ggtcagaatt agaaacaata aaaaataact
    10321 ttccagcaga attacggagt tctgaaacag ctgatttatt tatggctgtc attatgtatc
    10381 gtttgaaaga aaatggtcgt gttggagtta ttttacctga tggttttcta tttggtgaag
    10441 gtgtaaaaac tcgcttgaaa caaaaactgg tagatgagtt caacttgcat acgattatta
    10501 ggttgcctca tagtgtcttt gcaccgtata caggaatcca tacgaacatt cttttctttg
    10561 ataaaacaaa gaaaacagaa gaaacttggt tttatcgttt agatatgcca gatggttata
    10621 aaaatttctc gaaaactaag ccgatgaagt cagaacactt caatcctgtt cgtgactggt
    10681 gggaaaatcg tgaagagatt ctggaaggta agttctacaa atctaaatca tttacaccta
    10741 gtgaattggc tgagttgaat tataatttag accagtgtgg ttttccaaaa gaggaagagg
    10801 aaatcttaaa tccctttgag ttgattcaga attatcaagc ggaaagagca actttaaatc
    10861 ataagattga taatgtatta gctgatattt tgcagttgtt ggaggacaaa taatgacacc
    10921 agaacaactt aaagcaagta ttctccaaag agcgatggaa gggaaattag tgccgcaaaa
    10981 tcccaatgac gaacctgcaa gtgaattatt aaagagaatt aaagctgaaa aagaaaaact
    11041 tatcagtgaa ggaaaaatca aacgagataa aaaggaaact gagatatttc gtggtgatga
    11101 tgggaaacat tatgggaagt ttgctgatgg aagtactcaa gaaattgatg ttccttatga
    11161 tattcctgat acttgggagt gggtgaggtt ttctacattg gttgaaattg tcagaggtgg
    11221 ctctccacga ccaatcaaag attatcttac ttctgaagta gatggaataa attggataaa
    11281 aataggtgat actgaaaagg gtgaaaagta tataaataat gttaaagaaa aaatcaaaaa
    11341 atcagggctt aacaaaacta gatttgtaaa aaaaggtaca tttttgttaa ctaattctat
    11401 gagttttggt agaccttata ttttgaatgt tgatggtgca atacacgatg gatggttggc
    11461 tatttcgaac tatgaaaact cattaaataa agattaccta ttctatattc tttcatcaaa
    11521 tgtagtttat tctcaatttc tatctctaat tagtggagct gttgtgaaaa acttgaatag
    11581 tgataaagtt gcttctattc ttatccctct ccccccacta tccgaacaac aacgcataat
    11641 agaagcaatc gaatcagctt tagaaaaagt agatgaatat gctgaaagtt ataatagact
    11701 agaacagcta gataaagaat ttccagataa actaaaaaaa tctattcttc aatatgctat
    11761 gcaaggaaaa ttagttgaac aagacccaaa tgatgaatca gtcgaagttt tacttgaaaa
    11821 aatacgagca gaaaaacaaa aactctttga agaaggcaag attaaaaaga aagatttgga
    11881 catttctatt gtttcccaag
//
LOCUS       DBERXF010000054        11890 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.54, whole genome shotgun sequence.
ACCESSION   DBERXF010000054 DBERXF010000000
VERSION     DBERXF010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11890
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.54"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            152..397
                     /locus_tag="ACL8JK_001909"
     CDS             152..397
                     /locus_tag="ACL8JK_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786727.1"
                     /translation="MKAFYITIEKFIRDDESLKCYFIKVISSRSKVTSLDQIEADKTI
                     QRKYSSELKKFIGFYNEIICEENSFLHVRKRWSSWFR"
     gene            798..1790
                     /locus_tag="ACL8JK_001910"
     CDS             798..1790
                     /locus_tag="ACL8JK_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1786728.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1792..2610
                     /locus_tag="ACL8JK_001911"
     CDS             1792..2610
                     /locus_tag="ACL8JK_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1786729.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2612..3397
                     /locus_tag="ACL8JK_001912"
     CDS             2612..3397
                     /locus_tag="ACL8JK_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1786730.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3436..3714
                     /locus_tag="ACL8JK_001913"
     CDS             3436..3714
                     /locus_tag="ACL8JK_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HGS1786731.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTGFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3699..3896
                     /locus_tag="ACL8JK_001914"
     CDS             3699..3896
                     /locus_tag="ACL8JK_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1786732.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFLQLWNPQNPCQILIKKLE"
     gene            4428..10847
                     /locus_tag="ACL8JK_001915"
     CDS             4428..10847
                     /locus_tag="ACL8JK_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGS1786733.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     AENKEKHEDIHSAMETSQDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKEENSNK
                     SQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKELSSLKNTKVLYTYDRIF
                     NGGAIETTQDNLNKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFG
                     KNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAF
                     NYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSY
                     KMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAG
                     IPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFD
                     KVNIGGQSFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKI
                     AVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQV
                     FSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKE
                     IDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKST
                     YGYMSGTSMATPIVAASTVLIRPKLKEMLEKPVLKNLKGDDKIDLTSLTKIALQNTAR
                     PMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLK
                     EIKGDKKYFTIKLHNTSNRPLTFKVSASAVTTDSLTDRLKLDETYKDEKSPDGKQIVP
                     EIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEME
                     ALSSNGKKTDFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSKSKTMEGYDDDGKPKIP
                     GTLNKGIGGEHGIDKFNPAGVIQNRKDKNRTSLDQDPDLFAFNNQGVHAESTSGSKIA
                     NIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVVSREHF
                     IRGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQ
                     FEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTY
                     HKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQ
                     GRNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEKGMISY
                     YLVDPDQDSSKYQKLGEIPESKFKNLKNVKDDSLNKETAEVENNLLVDNQSIEGKSLF
                     NIHKTISTIRDFENKDLKKLIKKKYKQEDDFVNGGTRTVERDYKYDDKGNIIAYDDGT
                     DLEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKSIEIKATK
                     YDFHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDNDQKKAEIKIRMPEKIKETKSEY
                     PYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKV
                     TTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLM
                     SALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEA
                     IKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVN
                     ESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYL
                     QTGYSNLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFD
                     GEIQEQHIYINGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSE
                     LKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYV
                     INLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDH
                     SQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLG
                     LKKKNQD"
     gene            11474..>11890
                     /locus_tag="ACL8JK_001916"
     CDS             11474..>11890
                     /locus_tag="ACL8JK_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS1786734.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLED"
BASE COUNT         4173 a         1786 c         2372 g         3559 t
ORIGIN      
        1 gtacgaaaca attgctaaaa catttataga aattaatttt actttcccaa tcgatttgtt
       61 ctcatcttat ttcaatccgc tatatattat ggtatcgaat cttcatcaga atgataaaat
      121 taatcaattg atatctgatt acaaacagaa tatgaaagct ttttatatca ctattgaaaa
      181 atttatacga gatgatgaaa gccttaagtg ttattttata aaggttattt caagtcgttc
      241 caaggtaaca agtctagatc agattgaagc tgataaaacg atacaaagaa aatattcaag
      301 tgagctaaaa aaatttattg gattttataa tgagattatt tgtgaggaaa atagtttcct
      361 acatgtacga aagaggtggt cgagttggtt taggtagtcg atgcgtgagt tgataattct
      421 cagggtatgg acttcttttt catgaatgag gtaaaagagc aggtattgtt tagagacaat
      481 cattctgagc atattttctg gatagaggga gtatccgatt ttatgatcaa agttaatacc
      541 gccctctggt gagaagataa gtaggttggt aatttaaact attaaacaga atttttgatt
      601 aaaagtatta ttttatgaga gaaatcctaa tttcacaatc cataggcaaa cgcttgcatt
      661 tcgtttttta ttggactata ataggttggt ataaagcctt ttgtagtaat aaaatgtaga
      721 aggtgtagaa agcaaggatt tagaatattt gtagttaaaa acacaatgtt gctattcctt
      781 acgataggga gatagatatg gcaatgatag aagtggaaca tcttcagaaa aattttgtga
      841 agactgttaa ggaaccgggc ttgaaggggg ctttgcgctc ctttattcat cctgaaaagc
      901 agacctttga agcggtcaag gatttgacct ttgaggttcc aaaagggcag attttaggat
      961 ttatcggggc aaatggtgct gggaagtcga caaccattaa aatgctgaca ggaattttga
     1021 aaccaacatc tggtttttgt cggattaacg gcaagattcc ccaggacaat cggcaagatt
     1081 atgtcaaaga tattggcgta gtctttggac aacgcaccca gctatggtgg gatttggctc
     1141 tgcaagagac ctacactgtc ttaaaagaga tttatgatgt gccaaactcg ctctttcata
     1201 agcgcatgga ctttttgaat gaagtcttgg atttgaagga ctttatcaag gatcccgtgc
     1261 ggactctttc actgggacaa cggatgcggg cggatattgc ggcctccttg ctccacaatc
     1321 ccaaggttct ttttttagat gagccgacca ttggtttgga cgtttcggtt aaggataata
     1381 ttcgtcgggc aattactcag atcaatcaag aggaagaaac taccattctt ttgaccactc
     1441 acgatttgag tgatattgag caactttgtg atcggatttt catgattgac aaggggcaag
     1501 agatttttga tggaacggtg agccaactca aggagacctt tggtaagatg aagactctct
     1561 cttttgaact gctaccaggt caaagtcatc tcgtctctca ctatgaaggt ctgtctgata
     1621 tgaccattga tagacaagga aacagcctca acattgaatt tgatagttct cgctaccagt
     1681 cagctgacat tatcaagcaa accctgtctg attttgaaat ccgcgatttg aagatggtgg
     1741 atacggatat tgaggatatt atccgtcgct tctaccgaaa ggagctctag gatgatcaaa
     1801 ttgtggagac gttataaacc ctttatcaat gcaggggttc aggagttgat tacttaccga
     1861 gtcaacttta ttctctatcg gattggcgat gtcatggggg cttttgtggc cttttatctc
     1921 tggaaggctg tctttgattc ttcgcaagag tctttgattc agggcttcag tatggcggat
     1981 atcaccctct acatcatcat gagttttgtg accaatcttc tgactagatc cgattcgtcc
     2041 tttatgattg gggaggaggt caaggatggc tccattatca tgcgtttgtt gcgaccagtg
     2101 cattttgcgg cctcctatct tttcaccgag cttggttcca agtggttgat ttttatcagc
     2161 gttggccttc catttttaag tgtcattgtc ttgatgaaaa tcatatcggg tcaaggtatt
     2221 gtagaggtgc taggattaac tgtcctttat ctttttagct taacgctcgc ctatctgatt
     2281 aactttttct ttaatatttg ctttggattt tcagcctttg tgtttaaaaa tctttggggt
     2341 tccaacctac ttaagacttc catagtggct tttatgtcgg ggagtttgat tcccttggca
     2401 ttctttccaa aggttgtttc agatattctt tcctttttgc ctttttcatc cttgatttat
     2461 actccagtta tgatcattgt tggaaaatac gatgccagtc agattcttca ggcactcctt
     2521 ttgcagttct tctggctctt agtgatggtg ggattgtctc agttgatttg gaaacgggtc
     2581 cagtccttta tcaccattca aggaggttag tatgaaaaaa tatcaacgaa tgcatctgat
     2641 ttttatcaga caatacatca aacaaatcat ggaatataag gtggattttg tggttggtgt
     2701 cttgggagtc tttctggctc aaggcttgaa tctcttgttt ctcaatgtca tctttcaaca
     2761 tattccattc ctagaaggct ggacctttca agagatagct ttcatttatg gattttcctt
     2821 gattcccaag ggaatggacc atctcttttt tgacaatctc tgggcactag ggcaacgcct
     2881 agtccgaaaa ggagagtttg acaagtatct gactcgtccc atcaatcctc tctttcacat
     2941 cctagttgaa acctttcaga ttgatgcctt gggtgaactc ttagtcggtg gtattttatt
     3001 gggaacaaca gtgaccagca ttgtttggac tcttccaaaa ttcctgcttt tcctagtttg
     3061 tattcctttt gcgaccttga tttatacttc tcttaaaatc gcaacagcca gtatcgcctt
     3121 ttggactaag cagtcaggcg ccatgattta catcttctat atgttcaatg actttgctaa
     3181 gtatccgatt tctatttaca attctcttct tcgttggttg attagcttta tcgtgccttt
     3241 cgcctttaca gcctattatc cagctagcta tttcttacag gaaaaggatg tgttctttaa
     3301 cgtaggaggt ttgatgttga tttctctggt tttctttgtt atttccctta aactttggga
     3361 taagggctta gattcctacg aaagtgcggg ttcgtaaaag ctaaagtaag actaaaatca
     3421 agaaagaaac ttatgatgtt tgtaattgaa gaagtcaagg atgaaaatca aaaaaaggca
     3481 gttgtagctg aggttttgaa ggatttgcca gaatggtttg gaatcccaga aagcacacaa
     3541 gcctatatag aaggaaccac gacactgcaa gtttggaccg cctatcagga gagtgatttg
     3601 actggatttg taagcttatc ctattcgagt gaagattgtg cagagattga ttgtctcggc
     3661 gtaaaaaagc ttatcaaggt agaaaaattg ggagccaatt gcttgctact ttagagagtg
     3721 aagctcgtaa aaaagttggt tatctgcagg tcaaaacagt ggcagaaggt tctaataaag
     3781 attatgatcg aacaaatgac ttttatcgag gtcttggctt taaaaagtta gagatttttc
     3841 ttcaactatg gaatccgcaa aatccttgtc agattttgat taaaaagctt gaataatatt
     3901 acttgacatc tattctcaga gtgctatact gtaagtgtaa tcgccgattt agcttagttg
     3961 gtagagcaag gcactcgtaa agcctaggtt ataggtagat aaacgactga ggatttgaaa
     4021 aaatagatag gtagaagata accgttaagc cttattctta gcggttattt atattgttta
     4081 atagcgctga tatttcatca attatgcctg ttttcgtgtt tctggtagtt gttcaagttt
     4141 attgctacta tttttgatgg tatgaatgtg cttataatgt atccctgtta agtacgaaac
     4201 ttttgcatta ttttttaaca tatattaaaa aataaattaa tgtgtattaa tttttcttga
     4261 attaattttt tttaaatgat atactgtttt tatggagaga taacaattat atataaatgt
     4321 actactctat ttcctagata atacttagta aaacttttta taacaaaggc tagcaaagtt
     4381 aaagtttatt atctattgga agttatataa atatgtaagg aattaaaatg aaaaaaagta
     4441 cagtattgtc attaaccaca gctgcagtta ttttagcagc ctatgcccct aatgaggtag
     4501 tcttagcaga cacatctagc tctgaagatg ctttaagcat ctctgataaa gaaaaagtag
     4561 cagaaaataa agagaaacat gaagatatcc atagtgctat ggaaacttca caggatactg
     4621 aagaaaagaa aacaacaatt attgaggaaa aagaagttgt tagtaaaaat cctgtgatag
     4681 acactaaaac tagcaatgaa gaagcaaaaa tcaaagaaga aaattccaat aaatcccaag
     4741 gagatcatac ggactcattt gtgaataaaa acacagaaaa tcccaaaaaa gaagataaag
     4801 ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc aaggagctat
     4861 ccagtcttaa gaatacaaaa gttttatata cttatgatag aatttttaac ggtggtgcta
     4921 ttgaaacaac tcaagataat ctgaataaaa ttaaacaaat agaaggtatt acatcggttg
     4981 aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt ggagttgagg
     5041 aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt gatggtagag
     5101 gtatggtcat ttcaaatatc gatactggaa cagattatag gcataaggct atgagaatcg
     5161 atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga actgataaaa
     5221 attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt ggcaaaatca
     5281 ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg catattgcag
     5341 ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc atagatggaa
     5401 ttgcgcctaa tgcacaaatt ttctcttata aaatgtattc tgacgcagga tctgggtttg
     5461 cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac gttgatgttg
     5521 tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat tggcaagcta
     5581 ttagggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac tatgcgactt
     5641 ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg accgacactg
     5701 gaaatgtaac acgaactgca gcacatgaag atgcgatagc ggtcgcttct gctaaaaatc
     5761 aaacagttga gtttgataag gttaacattg gaggacaaag ttttaaatac agaaatatag
     5821 gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa gctcctagta
     5881 aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt ttggatctta
     5941 ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat gcttttaaaa
     6001 aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat tactacaata
     6061 gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt actaaaagtc
     6121 aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt aatcctgata
     6181 aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg gagcaatact
     6241 atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac gaaaaagaga
     6301 ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat atcatcgttc
     6361 cagcaggatc cacatcttgg gggccaagaa tagatttact tttaaaaccc gatgtttcag
     6421 cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca acttatggct
     6481 atatgtccgg aactagtatg gcgactccaa tcgtagcagc ttctactgtt ttgattcgac
     6541 caaaattgaa ggaaatgctt gaaaaacccg tattaaaaaa tcttaaaggt gatgataaaa
     6601 tagaccttac aagtcttaca aaaatagccc tacaaaatac tgcaagacct atgatggatg
     6661 caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacagcag ggggcggggc
     6721 taattaatgt ggccaacgct ttgagaaatg aagttgtagc gactttcaaa aacacggatt
     6781 ctaaaggttt ggtaaattca tatggttcca tttctcttaa agaaataaaa ggtgataaaa
     6841 aatactttac aattaagctt cacaatacat ccaacaggcc tttaaccttt aaagtttcag
     6901 catcagcggt gactacagat tctctaactg acagactaaa actggatgaa acatataaag
     6961 atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcatccagaa aaagtcaaag
     7021 gggcaaatat tacatttgag catgacactt tcactatagg ggcaaattct agctttgatt
     7081 taaatgcggt tataaatgtt ggggaggcta aaaataaaaa taaatttgta gaatcattta
     7141 ttcattttga gtcagtagaa gaaatggaag cattaagctc caatggcaag aaaaccgact
     7201 tccaaccatc tttatcaatg cccctaatgg gatttgctgg gaattggaac cacgaaccaa
     7261 tccttgataa atgggcttgg gaagaaggat caaaatcaaa aacaatggaa ggttatgatg
     7321 atgacggtaa accaaaaatt ccaggaacct taaataaggg gattggtgga gaacatggta
     7381 tagataaatt taatccagca ggagttatcc aaaatagaaa agataaaaat agaacatctc
     7441 tagatcaaga tccagactta tttgccttta acaaccaagg tgttcatgca gaatccacta
     7501 gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct caagatgctc
     7561 aactagaaag aggactaact ccatctccac ttgttctaag aagtgcagaa gaaggactaa
     7621 tttcaattgt aaacaccaac aaagaaggag aaaaccaaaa agaccttaaa gttgtatcaa
     7681 gagagcactt cataagagga attctaaatt ctaagggaaa tgacgctaag ggtatcaaat
     7741 catccaaact aaaagtttgg ggtgacttga aatgggatgg actcatctat aacccaagag
     7801 gtagagaaga aaatgcccca gaaagtaagg ataaccaaga tccagctact aagatacgag
     7861 gacaatttga accgattgcg gaaggtcaat atttctataa atttaaatat agattaacta
     7921 aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacaca gcccctaaga
     7981 ttgtttcggt tgatttttca aatcctgaaa aaattaagct aatcacaaag gatacttatc
     8041 acaaggtaaa agatcaatac aagaatgaaa ctttatttgc tagagatcaa aaagaacatc
     8101 ctgaaaaatt tgatgagatt gcaaatgagg tgtggtatgc aggagctgct cttgttaatg
     8161 aagatggaga ggttgagaaa aatcttgaag taacttatgc aggtgagggt caaggaagaa
     8221 ataggaagct tgataaagat gggaatacta tctatgaaat tagcggagca ggagatctaa
     8281 gaggaaaaat catcgaagta atcgccctag atggagcaag caactttacc aaaatccata
     8341 ggattaaatt tgctaatcaa gctgatgaaa aagggatgat ttcctattat ctagtagatc
     8401 ctgatcagga ttcatctaaa taccaaaagc ttggcgaaat tcctgaatct aaatttaaga
     8461 atttaaaaaa tgttaaagat gatagcctaa acaaagagac agctgaggtg gaaaataacc
     8521 ttttagtaga taatcagtct atcgaaggaa aatctctctt taatattcat aaaactattt
     8581 caacaattag agactttgaa aataaagacc taaagaaact cattaaaaag aaatataagc
     8641 aagaagacga ctttgtaaat ggtggaacaa gaacagtaga gcgtgattat aaatacgatg
     8701 ataaaggaaa tataatagcc tacgatgatg ggactgatct agaatatgaa actgagaaac
     8761 ttgacgaaat caaatcaaaa atttatggtg ttctaagtcc gtctaaagat ggacactttg
     8821 aaattcttgg aaagataagt aatgtttcta aaaatgccaa ggtatattat gggaataact
     8881 ataaatctat agaaatcaaa gcgaccaagt atgatttcca ctcaaaaacg atgacatttg
     8941 atctatacgc taatattaat gatattgtgg atggattagc ttttgcagga gatatgagat
     9001 tatttgttaa agataatgat cagaaaaaag ctgaaattaa aattagaatg cctgaaaaaa
     9061 ttaaggaaac taaatcagaa tatccctatg tatcaagtta tgggaatgtc atagaattag
     9121 gggaaggaga tctttcaaaa aacaaaccag acaatttaac taaaatggaa tctggtaaaa
     9181 tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt ctaagaaaag
     9241 gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta gaaggaaatg
     9301 gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat ctaagagtcc
     9361 tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga agtacccaag
     9421 ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg tttacattta
     9481 aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca gattcttcta
     9541 aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag tccaatgtag
     9601 aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta aacctttcaa
     9661 tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga aatccagaat
     9721 tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg agagttaatg
     9781 aatcggttgt agataattat ttaatctacg gagatttaca cattgataac actagagatt
     9841 ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg aaagactata
     9901 aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat cttcaaactg
     9961 gctatagcaa tttgaatgct aaagcagttg gagtccacta tcagttttta tatgataatg
    10021 ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat gctgatggaa
    10081 aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt gagattcaag
    10141 aacaacatat ttatataaat ggaaaagaat atacatcatt tgatgatatt aaacaaataa
    10201 cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat acaaccgtaa
    10261 aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct catagggtaa
    10321 ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa gaagatttta
    10381 ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt tgggaaattt
    10441 ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa gataccttta
    10501 taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa cctacttttg
    10561 atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat gaaagtcaca
    10621 gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact aaggatgtta
    10681 cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac aatcctaata
    10741 agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc ggaataatgt
    10801 ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagat aaaagctata
    10861 gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt tttgtgaaaa
    10921 cagccattta taactcaatt atttagttta cttcactatt gatactattt ggagttatta
    10981 atggacttag tttagataac taatgaattg attgaaaggg ttagtattga caatattggt
    11041 catattgatt agaaaataga gtctatcaaa atttaaaggc taatagaggt gatgagacaa
    11101 tttcaaggaa ttaagtagcg tttggttgct taattccttt ttatttggaa ggaagttttt
    11161 cgtaaccgcc caataacgaa gtctattgga cggttacgat atgatcactg acttcgtcag
    11221 ttctatctac aacctaaaaa cagtgttttg aacaacctgc ggctagcttt ctagtttgct
    11281 ctttgatttt cattgaatat tagaacagca aaaatgcttg gagtatttgt ttgtgtgttt
    11341 gtttttatat aacaaactat aaacaaaaca aaaatataaa aaaagagaca aaaaagaaca
    11401 gaaagtaatt gacaacggtt tcatatagtg ttatacttat ggcataaagt taatggaaag
    11461 aagggaaaac cttatggtat tagattattt ctttgacaaa aaccttgtgt tttgcttaga
    11521 agcggataat caagaacaac tctttgatca ggtagcaagc ttgttggaag aacgagaaat
    11581 tgtcactcca acttatcgtg aagccttgat cacgcgtgaa aagtcatttc caactggttt
    11641 agatatggaa tttctaggaa aggacttgcc aaatgtagcg attcctcaca cagatattgt
    11701 tcataatttg gctgaaaaag ttgtggtcgt tcgattagag aaaccggtga ctttccataa
    11761 tatgattgcg ccagataagg aagtagaagt atccttgctc ttctttatca tcaataactc
    11821 aagttcaagt caaacgaaca ttcttgctca gttaatggac ttcttcacag gaaatggtca
    11881 tcttgaagac
//
LOCUS       DBERXF010000055        11751 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.55, whole genome shotgun sequence.
ACCESSION   DBERXF010000055 DBERXF010000000
VERSION     DBERXF010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11751
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.55"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            172..2463
                     /gene="pcrA"
                     /locus_tag="ACL8JK_001917"
     CDS             172..2463
                     /gene="pcrA"
                     /locus_tag="ACL8JK_001917"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGS1786735.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDSDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2506..3186
                     /gene="radC"
                     /locus_tag="ACL8JK_001918"
     CDS             2506..3186
                     /gene="radC"
                     /locus_tag="ACL8JK_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGS1786736.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3183..3872)
                     /locus_tag="ACL8JK_001919"
     CDS             complement(3183..3872)
                     /locus_tag="ACL8JK_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGS1786737.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(3890..4531)
                     /locus_tag="ACL8JK_001920"
     CDS             complement(3890..4531)
                     /locus_tag="ACL8JK_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGS1786738.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4614..4829)
                     /locus_tag="ACL8JK_001921"
     CDS             complement(4614..4829)
                     /locus_tag="ACL8JK_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGS1786739.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(4837..5184)
                     /locus_tag="ACL8JK_001922"
     CDS             complement(4837..5184)
                     /locus_tag="ACL8JK_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGS1786740.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5189..6304)
                     /locus_tag="ACL8JK_001923"
     CDS             complement(5189..6304)
                     /locus_tag="ACL8JK_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGS1786741.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6314..7273)
                     /locus_tag="ACL8JK_001924"
     CDS             complement(6314..7273)
                     /locus_tag="ACL8JK_001924"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGS1786742.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7386..7955)
                     /locus_tag="ACL8JK_001925"
     CDS             complement(7386..7955)
                     /locus_tag="ACL8JK_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGS1786743.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8083..8754
                     /locus_tag="ACL8JK_001926"
     CDS             8083..8754
                     /locus_tag="ACL8JK_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGS1786744.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGVKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8738..9556
                     /locus_tag="ACL8JK_001927"
     CDS             8738..9556
                     /locus_tag="ACL8JK_001927"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGS1786745.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9553..10449
                     /locus_tag="ACL8JK_001928"
     CDS             9553..10449
                     /locus_tag="ACL8JK_001928"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS1786746.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10493..11467
                     /gene="pta"
                     /locus_tag="ACL8JK_001929"
     CDS             10493..11467
                     /gene="pta"
                     /locus_tag="ACL8JK_001929"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGS1786747.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         3420 a         2255 c         2535 g         3541 t
ORIGIN      
        1 aggtattgag ctagtttatg aaaaaattgg gtgaaaagtc gagtgtttta gaaacccaca
       61 gtgtagtatt ctagtttcaa tccactatat tttgctactc cccgtaaagt ttctattttc
      121 cctgatttct gatataatag aaatattgac ttcaagagta aggaagagaa gatgaacgca
      181 ttattaaatg gaatgaatga ccgtcaggct gaggcggtgc aaacgacaga aggtcccttg
      241 ctaatcatgg caggggctgg ttctggaaag actcgtgttt tgacccaccg tatcgcttat
      301 ttgattgatg aaaagctggt caatccttgg aatatcttgg ccattacctt taccaacaag
      361 gctgcgcgtg agatgaaaga gcgtgcttat agcctcaatc cagcgactca ggactgtctg
      421 attgcgacct tccactccat gtgtgtgcgt attttgcgtc gcgatgcgga ccatattggc
      481 tacaatcgta attttacaat tgtggatcct ggtgaacagc gaacgctcat gaaacgtatt
      541 ctcaaacagt tgaacttgga ccctaaaaaa tggaatgaac gaactatttt ggggaccatt
      601 tccaatgcta agaatgattt gattgatgat gttgcttatg ctgcccaagc tggcgatatg
      661 tatacgcaaa ttgtggccca gtgttataca gcctatcaaa aagaacttcg tcagtctgaa
      721 tccgttgact ttgatgattt gattatgctg accttgcgtc tctttgatca aaatcctgat
      781 gttttgacct actaccagca aaaattccaa tacatccacg ttgatgagta ccaagatacc
      841 aaccacgctc agtaccaatt ggtcaaactc ttggcttccc gttttaaaaa tatctgtgtg
      901 gttggggatg cggaccagtc tatctacggt tggcgtggtg ctgatatgca gaatatcttg
      961 gactttgaaa aggattaccc caaagccaag gttgttttgt tggaggaaaa ttaccgctca
     1021 accaaaacca ttctccaagc ggccaacgag gttattaaaa ataataaaaa tcgccgtcct
     1081 aaaaatctct ggactcaaaa cgctgatggg gagcaaatcg tttactatcg tgccgatgat
     1141 gagctggatg aggctgtatt tgtagccaga accatcgatg aacttagtcg cagtcaaaac
     1201 ttccttcata aggattttgc agttctctat cggactaatg cccagtcccg tacaattgag
     1261 gaagccctgc tcaagtctaa cattccttat accatggttg gcggaaccaa attctacagc
     1321 cgtaaggaaa ttcgcgatat tattgcttat ctcaacctta ttgctaattt gagtgacaat
     1381 attagttttg agcgtattat caacgagcct aaacgtggaa ttggtctagg tacagttgag
     1441 aaaatccgtg attttgcaaa tttgcaaaat atgtctatgc tggatgcttc tgctaatatt
     1501 atgttgtctg gtatcaaggg taaggcagcc caatctatct gggattttgc caatatgatg
     1561 cttgatttgc gggagcagct agaccactta agcattacag agttggttga gtccgtccta
     1621 gaaaaaacag gttatgtcga tattcttaac gcccaagcga ctctagaaag caaggcacgg
     1681 gttgaaaata tcgaagagtt tctttctgtt acgaagaact ttgatgacac cacggatgtg
     1741 acagaagagg aaactggtct ggacaaactg agtcgtttct taaatgactt ggctttgatt
     1801 gccgacacag attcaggtag tcaggagaca tcagaagtga ccttgatgac cctgcatgct
     1861 gccaaaggtc tcgaatttcc agttgtcttt ttgattggga tggaagaaaa tgtctttcca
     1921 cttagtcgtg cgactgaaga ttcagatgaa ttagaagaag agcgccgtct agcctatgta
     1981 ggtatcacgc gtgcagagaa aattctctat ctgaccaatg ccaactcacg cttgcttttt
     2041 ggtcgtacca attataaccg tccgactcgt tttattaacg aaatcagttc agacttgctt
     2101 gagtatcaag gtctggctcg tcctgcaaat acaagcttta aggcatcata tagcagtggt
     2161 agtatttcct ttggtcaagg tatgagtttg gctcaggctc ttcaagaccg taaacgcggt
     2221 gctgccccaa aatcaatcca gtcaagcggt cttccatttg gtcaatttac agctggcgca
     2281 aaaccagcat ctagcgaggc aaattggtcc attggtgata ttgctctcca caagaaatgg
     2341 ggagagggaa ccgttctgga agtttcaggt agcggtgcta ggcaggaatt gaaaatcaat
     2401 ttcccagaag taggtttgaa aaaactttta gccagtgtgg ctccaattga gaaaaaaatc
     2461 taattttcca tccttctcac gaataataaa gtgaggagga tttttatgta cagtatttca
     2521 ttccaagaag attcactatt accaagagaa aggctggcca aggaaggagt tgaagcgctt
     2581 agtaaccaag agttgctagc tattttactc aggacaggaa cacgtcaagc tagcgttttt
     2641 gaaattgccc aaaaagtctt gaacaatctt tcaagcctaa cggatttgaa aaaaatgacc
     2701 ctgcaggaat tgcagagttt gtctggtatt gggcgtgtta aggccataga attacaagct
     2761 atgattgaac tggggcatcg tattcacaaa cacgagactc ttgaaatgga aagtattctc
     2821 agcagtcaaa agttggccaa gaagatgcag caggaattag gggataaaaa acaagagcac
     2881 ctggtggcac tctatctcaa tactcaaaat caaatcatcc atcagcagac catttttatc
     2941 gggtctgtaa ctcgtagtat cgctgaaccg cgagagattc ttcactatgc aatcaagcat
     3001 atggcgactt ctcttatctt ggtccacaat catccttcag gagcggtagc gcctagccaa
     3061 aatgatgatc atgtcactaa acttgttaaa gaagcctgcg aattgatggg gattgttctc
     3121 ttggaccatt tgattgtctc tcattctaat tactttagtt atcgtgaaaa gacagattta
     3181 atctaaagtt cattaacgac atagtcaaag agttttttat ctttgggacg attttcaaaa
     3241 agaagttctg gatgccattg gacaccgaga aaggcgacat catccgtact catgacagcc
     3301 tcaatgatac catctttagg atcatgagcc acaactttta aatttggtgc taagtccttg
     3361 atgctctggt ggtggaagga gttgatatga gagatttctc catagatttc ttggagaacg
     3421 gtatctggtt ctgttaccaa gcgttgagtt gtgtactcaa cagaagaatc ctgccaatgg
     3481 tcttcgatat cttggtacaa agttccaccc atggcaacgt taaagagttg ggtaccacgg
     3541 cagacagaga aaatgggctt tttctgttta atagcttcct tgatgagggc cagttcgaag
     3601 atatctcttt gaaggtgata gtcatcacta tcaatggttt tgggttcgcc ataaaatttt
     3661 ggatcgacat tttgcccacc tgtcaagatg agcttgtcaa tcaaactgat atagtggcag
     3721 gccatttctt gatcaccaat cggtaggatg atgggaatcc ctccagcatc tttaacgcct
     3781 tcaacaaagc cttttgctgc gtagctcatc atgatgtcat catctggatg agttttttcg
     3841 tttcctgtaa tcccaataac tggttttttc ataaaatgat tttcgctttc taatcctctt
     3901 ttcgcatgaa gtagaggagg gtttggagtt cacttgtcaa atcgacatac tgaacgacca
     3961 cgtcttttgg taaatgcaga tggactggtg aaaaactgag aattcctttc acaccagcat
     4021 caaccaagag attagcaacc tcttgtgact tgacgctggg aacagttagg atagcagtct
     4081 tcacatcagc atccttgatt ttatccttga tctgagaaat cccgtaaatg ggaatcccgt
     4141 caggagtttg ggtaccgact tcaggatggt cgtctaggtc aaaggccatg ataatcttca
     4201 tcttgttacg ttcgtggaag cggtagtgga gaagggcatg gcccatattt ccaataccaa
     4261 ccagcatgac attggtaata gagttgtcat tgagcaaatc ggcaaaaaat gtcattagtt
     4321 ttttgacatc atagccaaaa ccacgacgac caagttcacc aaaataggaa aaatcacgac
     4381 gtacggtcgc tgaatcaata ccgatagcct ctgcaatttg cttagagttg gcacgttcaa
     4441 tcttttctgc atgaaatctc ttaaaaattc gatagtagag agagagtctt tttgctgtag
     4501 cttttggaat agcaaactgt ttatctttca caaaatcaca acctttctat tcttctattt
     4561 tatagaaaca ttgtgaaaaa atcaacaaaa ataagaaaaa actaagaaaa atcttagttt
     4621 tgatgtaaaa aatctgcatg agatagaaaa cggtagaggt ctccgaccag cccctgataa
     4681 acttttttgc ccctaaaagt cagagaagtc acataaagtg tatctggtaa ggttacacat
     4741 cctgacaaag tcaacatgag agcctcatga tcctcatact tgagagtacg ctctacatga
     4801 tagcagtcct tataggtcag ttcaaacatt ttggctctat ctttccgatt ttgtaaagac
     4861 accacgttct accaagctat ccatgaggaa gtagaatttt tcctgatgaa tatggtggtc
     4921 ttctgatttg aaaatatcaa ctagacgaag gccaaacttg tcagtgatat tgattttagc
     4981 ccctgtaagt tccttgttaa tgatgatttt gagttggaag ccttcaccgc tgtttggcac
     5041 tttttccaaa aggcgagtca gttcatagtt accaacctta gtttcaaaaa aggtgttatc
     5101 tttgagggtg aattttttaa cagaagggct aagagtgtaa tcgtaacgac aattttttaa
     5161 ctgaatgatt ttttcaaatg ccatatggct aacctccgat aatttctttt aaggtttttg
     5221 cgagggtttg taggtcttca acggtatttt gtggcgacaa actgatgcga agggattcct
     5281 tcaagcgttc tgaatttgcg ccatacatgg ctttaagaac atggctggat tggacaacgc
     5341 ctgcagtaca ggctgagcca gtagagattg aaattccagc taaatctagc cgaaggagta
     5401 agaggtcatt tttctgacca ggaaatccaa tattgagaac ataagggaga tgatgttttc
     5461 ctctattcaa gtaatactga atgccctcca gctctgccag aaaggcagtt tctagatttt
     5521 gtacatgttg aaaatgttct tcttgttttt ctaggtcttc ttttagggct gcaaccatgc
     5581 ctacgatggc aggcagattt tcagttcctg cacgtttttt ctgttcctga tctccgccat
     5641 gtagatagga atcaaagtcc atgctagatg cgtagagaaa accgattccc ttaggaccat
     5701 ggaatttgtg ggcagaagca gtgagaaaat caatgcccaa ttcttctgaa tgaattggga
     5761 ttttaccaat agcctgaact gcatcaacat gataggcagc agggtgttgc ttgagtattt
     5821 ggccaatttc agcgatggga agtaggtttc ctgtctcatt attggcaaac atagtagaaa
     5881 ccaaaatcgt atcgtcacgt aaagcctttt gaatttgctg ggctgtgatt tcttgatttt
     5941 ctggctggat aatggttgct tcaaacccaa agtgttgaac caagtaatca attgtttcaa
     6001 ggacagcatg gtgctcgatg gcagttgtga tgatatgttt tccttgttct tggtgacgaa
     6061 gacagtagcc aatgatggta gtattattgc cttcagtccc accagaagtg aaaaagatat
     6121 gttgaggttt tgtccttagt aactgggcta gttcctgacg ggcttctcgc aagagtttgc
     6181 cagcttgacg accatgacca tgaatactag aaggatttcc gtgggtttct tgcataacct
     6241 tggtcatagc tgaaatagca actgctgaca taggagtcgt tgcagcattg tccaaataaa
     6301 tcaaagaatc accttatttc tttttattgt aggcaaagag tgggctgact ggttttcttt
     6361 cgtgaatacg gacgatagca tcaccaatta actcactagc agtgatgtag catacatttt
     6421 taggagtttt ttcttttgtt gctactgaat cagtcacaag aatttcttta atattagtat
     6481 tgtcaagaag ctcagcagct ccctcgacga agagaccgtg gctagaaaca gcataaattt
     6541 ctgtagctcc ttcacgttca acgattttag aagcttcaga gaaggtacgt cctgtattta
     6601 aaatatcatc aatcaagata gctttcttac cttcaacatc accaataata taaccttcgt
     6661 tacgagttgc atcgtcttga gggtagtcga taatggcgat aggagcatca agatattcag
     6721 ccaggctacg cgcacgtttg acacctgaat ttttagggct aacgacaaca acatctgaac
     6781 caagcaatcc tttatcgcag taatgttttg cgaatagggg aacagtgaaa agattatcca
     6841 ctggaatatc aaagaaacct tgaacctgaa cggcatgcaa atcaagagtc aggatacgat
     6901 caactccagc cttaaccagc atattggcaa ctagttttgc tgtaagtggc tcacgaggac
     6961 aagcaatgcg gtcttgacgt gcatagccaa aatatggaag gacaacgttg atactgtggg
     7021 cacttgcacg cacacaagca tcgaccatga ttaacaattc cattaggtgg ttgttgacag
     7081 ggaaacttgt tgattggatg atgtaaacat cataaccacg gacactttct tcgatattta
     7141 cttggatttc tccgtctgaa aattgacgtg atgatagttt tccaagtggg acaccaacag
     7201 cttgtgcaat tttttgtgca atctcttggt tagagttgag tgcgaaaagt ttcatgtttt
     7261 ttctatctga cattatagac cgtcctctgt aaactttata aatcctagtt atatttacct
     7321 tacatatatg aactgggatt tgtgtatttt tatcttttct attttaccaa aaaatggaga
     7381 ttatttcagc tatttttcat acttttgaca aatcgaacca attttgaagg agctttttgg
     7441 taggaaatct gatttttctc taaaaattgt cggaaatcct gtttgccttg ctcatgattt
     7501 tccacttcaa gctccaattc gtaatctgtt atatcaaagt atcggctctg atccagtgcc
     7561 atgagaccaa tagctgtttt catttcatag cgaagcgttg ttagacaacc aagaacctgc
     7621 cagttcttac tttggatacc atgtttcgcc aattcatcca gtactagccc ttgaggaagt
     7681 tcttccttac tcagatagtt ctcagcatct tttagttgca atttttggtt gtattccatg
     7741 tttccaacac tctgcgggac tttgagtgtc aactcagccc agtcttcaaa ggttcgaatg
     7801 cgcatagcga ctttcttttc tcgcagttca aaatcaggcg tgtcgatgta gtaatttgtt
     7861 tgaagaacag gagtgacacc tgtgaactgg tcttttagac gattgtattc atcttttttc
     7921 aatagtgttt tcaattcaat ttctaaatgt ttcatttttc ttaccttttt ttatcgttga
     7981 aagcggattt atggtataat aagcattgta tttattgtat atgaatctgg agaaaaaatc
     8041 aaagatattt ttgacggata atatgagaac aagggagaat atatgacctt agaatgggaa
     8101 gaatttctag atccttacat tcaagctgtt ggtgagttaa agattaaact tcgtggtatt
     8161 cgtaagcaat atcgtaagca aaataagcat tctccaattg agtttgtgac cggtcgagtt
     8221 aagccaattg agagcatcaa agaaaaaatg gctcgtcgtg gcattactta tgcgaccttg
     8281 gaacacgatt tgcaggatat tgctggctta cgtgtgatgg ttcagtttgt agatgacgtc
     8341 aaggaagtag tggatatttt gcacaagcgt caggatatgc gaatcataca ggagcgagat
     8401 tacattactc atagaaaagc atcaggctat cgttcctatc atgtggtagt agaatatacg
     8461 gttgatacca tcaatggagt taagactatt ttggcagaaa ttcaaattcg tactttggcc
     8521 atgaatttct gggcaacgat agaacattct ctcaactaca agtaccaagg ggatttccca
     8581 gatgagatta agaagcgact ggaaattaca gctagaatcg cccatcagtt ggatgaagaa
     8641 atgggtgaaa ttcgtgatga tatccaagaa gctcaggcac tttttgatcc tttgagtaga
     8701 aaattaaatg acggtgtagg aaacagtgac gatacagatg aagaatacag gtaaacgaat
     8761 tgatctgata gccaatagaa aaccgcagag tcaaagggtt ttgtatgaat tgcgagatcg
     8821 tttgaagaga aatcagttta tactcaatga taccaatccg gatattgtca tttccattgg
     8881 cggggatggt atgctcttgt cggcctttca taagtacgaa aatcagcttg agaaggtccg
     8941 ctttatcggt cttcacactg gacatttggg cttctataca gattatcgtg attttgagtt
     9001 ggacaagcta gtgactaatt tgcagctaga tactggggca agggtttctt accctgttct
     9061 gaatgtgaag gtctttcttg aaaatggtga agttaagatt ttcagagcac tcaacgaagc
     9121 cagcatccgc aggtctgatc gaaccatggt ggcagatatt gtaataaatg gtgttccctt
     9181 tgaacgtttt cgtggagacg ggctaacagt ttcgacaccg actggtagta ctgcctataa
     9241 caagtctctt ggcggtgctg ttttacaccc taccattgaa gctttgcaat taacggaaat
     9301 tgccagcctt aataatcgtg tctatcgaac actgggctct tccattattg tgcctaagaa
     9361 ggataagatt gaacttattc caacaagaaa cgattatcat actatttcgg ttgacaatag
     9421 cgtttattct ttccgtaata ttgagcgtat tgagtatcaa atcgcccatc ataagattca
     9481 ctttgtcgcg actcctagcc ataccagttt ctggaaccgt gttaaggatg cctttatcgg
     9541 tgaggtggat gaatgaggtt tgaatttatc gcagatgaac atgtcaaggt taagaccttc
     9601 ttaaaaaagc acgaggtttc taagggattg ctggccaaga ttaagtttcg aggtggagct
     9661 attctggtca ataatcaacc gcaaaatgca acgtatctat tggacgttgg agactacgtt
     9721 accattgaca ttcccgctga gaaaggcttt gaaaccttgg aggctattga gcttccatta
     9781 gatattctct atgaggatga ccactttcta gtcttgaata aaccctatgg agtggcttct
     9841 attcctagtg ttaatcactc taataccatt gccaatttta tcaagggtta ctatgtcaag
     9901 caaaattatg aaaatcagca ggttcacatt gttaccagac tagataggga cacttctggc
     9961 ttgatgctct ttgccaagca cggttatgcc catgcacgat tagacaagca gttgcagaag
    10021 aaatctatcg agaaacgcta ctttgctttg gttaagggag atggacattt ggaaccagaa
    10081 ggggaaatta ttgctccgat tgcgcgtgat gaagattcca ttattaccag acgagtggct
    10141 aaaggcggaa agtatgccca tacttcatac aagattgtag cttcttatgg aaatattcac
    10201 ttggtctata ttcacctgca cactggtcga acccatcaaa tccgagtcca tttttctcat
    10261 atcggttttc ctttgctggg agatgatttg tatggtggta gtctggaaga tggtattcaa
    10321 cgtcaggctc tgcattgcca ttacctatcc ttttatcatc catttttaga gcaagacttg
    10381 cagttagaaa gtcccttgcc ggatgatttc agtaacctta ttacccagtt atcaactaat
    10441 actctataaa aactgtctca gagtataatt attatcttaa aggagaaaac tcatggaagt
    10501 ttttgaaagt ctcaaagcca accttgttgg taaaaatgct cgtatcgttc tccctgaagg
    10561 ggaagagcct cgtattcttc aagcaacaaa acgcttagta aaagaaacag aagtgattcc
    10621 tgttttgctt ggaaatcctg aaaaaattaa aatttatctt gaaattgaag gaatcatgga
    10681 tggttatgag gtcatcgacc ctcaacatta tcctcaattt gaagaaatgg tttctgcctt
    10741 ggtggagcgt cgcaagggca aaatgactga agaagatgta cgcaaggttt tggttgaaga
    10801 tgtcaactac tttggtgtga tgttggttta cttgggcttg gttgatggaa tggtgtcagg
    10861 agcgattcac tcaacagctt caacagttcg cccagctcta caaatcatca aaactcgtcc
    10921 aaatgtaact cgtacttcag gagccttcct catggttcgt ggtacggaac gttacctatt
    10981 tggagactgt gccattaata tcaatccaga tgcagaagcc ttggctgaaa ttgccatcaa
    11041 ctcagcaatc acagctaaga tgtttggcat cgaacctaaa attgccatgt tgagctattc
    11101 tactaaaggt tcagggtttg gtgaaagcgt tgataaggtc gttgaagcaa ctaaaattgc
    11161 tcacgacttg cgtcctgacc ttgaaatcga tggtgagttg caatttgatg cggcctttgt
    11221 tcccgaaact gcagctctga aagctccggg aagtacagta gctggtcaag caaatgtctt
    11281 catcttccca ggtatcgagg caggaaatat cggttacaag atggctgaac gcctgggtgg
    11341 ctttgcggct gtaggacctg ttttgcaagg tttaaacaag ccagttaatg atctttctcg
    11401 tggatgtaat gcagatgatg tttacaagtt gaccctcatc acagcagctc aagcagttca
    11461 tcaatagtga aaactataaa gtgatatact atgctatact gtagttatga aactatgtac
    11521 gaaaagcact gccattaatt cctgagaact aaattactga ttggtgtcaa aaaggaaaac
    11581 ttccaagcga tgatatcctg tctatacacg acctatagaa atctgtaata tacatatccg
    11641 taaaacgata aattcccttt ttgattttaa atgagtatga aaagagaatt ttttggctct
    11701 ttgtcaactg tagtgggttg aagtcagcta agctcgagaa aggacaaatt t
//
LOCUS       DBERXF010000056        10853 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.56, whole genome shotgun sequence.
ACCESSION   DBERXF010000056 DBERXF010000000
VERSION     DBERXF010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.56"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(212..1636)
                     /locus_tag="ACL8JK_001930"
     CDS             complement(212..1636)
                     /locus_tag="ACL8JK_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HGS1786748.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHTAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2181..4460)
                     /gene="pulA"
                     /locus_tag="ACL8JK_001931"
     CDS             complement(2181..4460)
                     /gene="pulA"
                     /locus_tag="ACL8JK_001931"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HGS1786749.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAAFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4572..6530)
                     /gene="ligA"
                     /locus_tag="ACL8JK_001932"
     CDS             complement(4572..6530)
                     /gene="ligA"
                     /locus_tag="ACL8JK_001932"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGS1786750.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVADSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6623..7801)
                     /locus_tag="ACL8JK_001933"
     CDS             complement(6623..7801)
                     /locus_tag="ACL8JK_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS1786751.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LNMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7881..8744)
                     /locus_tag="ACL8JK_001934"
     CDS             complement(7881..8744)
                     /locus_tag="ACL8JK_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGS1786752.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDATYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8747..10648)
                     /locus_tag="ACL8JK_001935"
     CDS             complement(8747..10648)
                     /locus_tag="ACL8JK_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS1786753.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3277 a         2380 c         1922 g         3274 t
ORIGIN      
        1 acttcaatgt actatatata gtaaaatgaa ataataacag gacaaatcga tcaggacagt
       61 caaatcgatt tctagcaatg ttttagaagt agagctgtac tattctagtt tcaatatact
      121 ataataccaa aaagttcgta ttttttctat aattattatt attttatagc aaaaaaataa
      181 aaccaggaaa acaatttcct ggttttacac gttatttcac atcaaaaaca atggatttga
      241 catttgtcat cgcttcaatg ctatatttaa ttccttgcac tccagctcca gaacctttga
      301 caccaaggaa tgggaaatta tctggaccac gctgggtttt attattaatg tggactgtac
      361 ctacttcaag tttttcagca atttcaaagg cttttttgaa atcatttgta aagactgatg
      421 attgaaggcc gaattcagat tcgttggcaa aggcaatagc ttcctctaca ctagccacac
      481 gaatgattgg taaaacagga ccaaatggct cttcccatgc cactttcata tcttttgtaa
      541 cttggtcaaa aagcactggc cagaggagat tgccctcacg tttgattggt gtaagagcct
      601 gagcctcttt ttcttgtgca tcctcaatca agccccaaat gaagtcggct gaagcattgt
      661 caataacagg tgtaatatca gcattgtcaa atggatcacc aactgttaat ttagaaactt
      721 cttcctgaag caaagtagct aatttatctg ctacactttc gagaacaatg acacgtttaa
      781 tggccgtgca acgttgtcct gagtagctaa aggctcccgc aacaatttgc ttggcagtat
      841 gttccaaatc tgcatcttct agtacaagag ctgcatcttt cccaccaagt tccaacatga
      901 taggacgcat accagctaaa cgaccaatac gttctccaat aggagttgaa cctgtaaagt
      961 tgatgaaatt gacttctttg tgctcaatga tataatcccc aatttctgaa ccacgacctg
     1021 taatggtgtt gaaaacacct gccggaatcc ctgcttcttc aaatgcttta gccaacaaga
     1081 gtccagaaat ggaaccttgt gttggtggct taaacatgac cacattccct gcaatcaagg
     1141 caggtgcaat tttagaagca gataaattaa ctggataatt aaaaggagca atcgctagca
     1201 cgataccaac tggttcacga cggacaacag ccagtttgtt tttacttgct gcctcaaaac
     1261 caccaccttc cattgcttgt ccagtgatac ggagaccttc ctcagcagca taacgaatca
     1321 agtctgctgt acgcactact tctccaattg ctgctttaat cccttttgct acttctttgg
     1381 caaggatagt accaattttt tccttatcgc gttctaaaat agctgctgtt ttatgcaaat
     1441 aagccgcacg ttcaattgct gataaagctc gccatgctgg cagggctgca cgcgcagctt
     1501 gcatagcctc atcagcttca gtctgagtca tggctggaac tgtacccaat tcttcttgat
     1561 tgattggtga ataaatcgta atttcttgtt cagatgattt ccattttcca tttactaaat
     1621 tctgatatct tgtcaaattc ttgtcctcct gaaaatgatt aagatatatt ttaccaaatt
     1681 ttcagaaaat cacaaccctt tttgcaaaat ttttgagatt attttcacaa tcttgatttt
     1741 tcaaagtata ctcaataaaa attaaaaaaa tccactacgt caaggcgagg ctaatgtggt
     1801 ttgaagaaat tttcgaagag cgtgaatgag tatcatctat agtaaaataa aaaaactgaa
     1861 caatttggtt ggggacagcc aaaccaattt ctcacaatgt ttcagaaaca agggtgtgct
     1921 attccaattt cagcctacta taactgtcat agattgctga aacaaagtct agataaaagt
     1981 cttcataata aaaagacctc ctatcaagtg ttcaaaaact ttgataggag gtcttgtttt
     2041 gtgaaaatat ttatcaaatt ttctatacaa gtgagctgtt agccaggttc tttctattct
     2101 ttcaatttca atgaatggat tttttactaa tactcataac tgggaatttg tctgtgtaaa
     2161 aatagcgaga tagatggtat ttataaaaca ctcaagacag ctagactaat atcatttaaa
     2221 acattatctt cttttgagcg actgttggtt accaacatag ctaaatttcc tgcattttca
     2281 aattgatagg gttctgattt agcattcaca accaccaaga ggtgttcttt gccgtgaact
     2341 tcatagataa ggtagccgct atgttcaatc gcagaatgca caaagacatg atggtaaatt
     2401 tcatcatagc tagagtaaga aaaggcacca gtttttgtct tcaatcggat gacttgacgg
     2461 ataaactcaa tactgtcttg acgctcatta atcaagttcc agttcacttg gttcacactg
     2521 tcaggagcat tatagctatt catcgcacgc tctctatcat catgggtcaa ctcaccattt
     2581 tcaccagtcg caaccagttt ggtacgacca aattcttgac cgatttccat aaaggccatc
     2641 ccctgcatga gcagattcat ggctgtggca gtttcgacct tgcgcatgat ttgctctgaa
     2701 ctttggtctg gatgaagggt tgccaataaa tcgtgaagat tgtaattgtc atgggcttct
     2761 acatagttaa gcacctgatt tggatgtgta tagcttccta attcacgact tcctaggatt
     2821 gctttagcta gaattggctc tgtcgcagca ccactgacaa aacctgactt gatagcacca
     2881 taaacttctc cccctttgac agcatcgcgc tgattgtcat taaagaaacc aatatttggc
     2941 atctggtagg cattgtcctt cttggcctta tcataagggg caagacctgt tcccatatcc
     3001 catccttctc catagaggat aatgttggag tcgatttcat ccaagctttg acgaatcatc
     3061 tgcatggtct tgacatcatg aatccccatc aagtcaaaac ggaagccgtc aatattatat
     3121 tcctgcaccc agtatagaag agaatcaatc atatacttgc gaaacatttc gtgttcactg
     3181 gctgtttcat ttccaacacc cgttccattc tggaaggtac catctggatt catacgataa
     3241 tagtaatcag ggactgttgt ttggaatgct gcatcaacaa ctgagaaggt atggttatag
     3301 actacatcca taatgactcc aatacccgca tcgtgataag cttgaaccat caccttcaaa
     3361 tcacgaatga cctgagctgg atcatctgga ttagttgaaa aactagtttc tggcgcgtta
     3421 tagttttgtg gatcataacc ccagttgtag gttacatttc catcctcatc gtattcttta
     3481 tgacggtctg caattggttg caattgaaca taattgtagc ccagcttctt gatgtaatca
     3541 aaagcagttg actggccgta ttggttaact gttccagcct gagcagcacc caagaaagtt
     3601 cctcgaagat gttcatctac acccgatgta ggtgatttag tcaaatcacg aatatgcatt
     3661 tcacagataa ctgccttaca tggattttcc aagcgccaag tagcctccga accgtgctta
     3721 acctcgaagt tttcaacttg cttttctaca tggctcagaa tagctgaacg tttgccatca
     3781 gggctggtcg cgattgtata aggatcacgt gtcagtgttt ggtgatgagg gaattggact
     3841 tgatactgat aagtcttacc taccaaatct tcttcaacat ccaaactcca gacaccgatt
     3901 gtattgtcct tatgattata agagtagcta ttgcctcttt tcatctcaaa agtcttccaa
     3961 acgggtgcat cattagcagc tgattcataa acgacaactt gcacttctgt cgctgtaggt
     4021 gaccagaggg aaaaatgagc ctgattgtcc tctacacggc aacccaattc tccttggtaa
     4081 ccccaatgat gatcaaaact agcactgtta atggccttat caaaggcaaa aggattttga
     4141 tttttataga aaggactggc aatagcagga ttttcagagt aataaatcct atcatcgcct
     4201 tccaaaatcc agacctctgt taatagggga tagtgattaa aacggataga atattcttta
     4261 ctagtttgac ctgtatgaac cacaaaattc aagctttcta taacatgtga acttgggtgt
     4321 tcaaagctaa ataaagctcc aaaataatct tctttgtagg ttagcaaatc aattcgttga
     4381 tcctgacttt ttacaaagga gcaagtgtca tattctccat tcttacgatg gtaatgaatg
     4441 cgcatagggt agttatacat tttttatttt tcctttttac tttgtttcta tttcactaat
     4501 aaatttttgt caatctcgtc tcaattaaca gacatagtca tattctctaa actctgtttt
     4561 taaacgatcc attacaaact ttctagccat gcctcatctc tgacctggat accaagttct
     4621 tgtgcttttt gcagtttact tccagcgtct gcacctacca cgacgaggtc ggtcttttta
     4681 gaaacactac ctgtcacttt ggcacccaga ctttcgagtt tacttttagc ttctgagcgc
     4741 ttgagtcgtt ccaattttcc tgtcaatacc acggtcaaac ctgacaaggc cgcatccgct
     4801 actaccgtct gtcctttata gtccagattg accccagttt ctttcaattc tctgagcaga
     4861 atttcagagc cttctgtcgc aaaataagtc tgaagacttt tggcaatcac gccacctaga
     4921 ctttcaatac tagccacttc ctctgaatct gcctgagaca gattttcaat tgaatggaaa
     4981 tattgaagta aaagctgact aaccttgctt ccgacatgac gaattcccaa accaaataag
     5041 agcttctcgg cagaattttc ctttgatgct tggatagcct gatacagttt agcagcggac
     5101 ttttccttaa ccccctctaa aaggaggaaa tcctcttctt gcaaacgata aatatccgcc
     5161 acatccttga ctaaattagc agcaaaaagc ttctcaacaa tagatggacc aaggcctgta
     5221 atattcatag catcacgaga agcaaagtga atcaagcctt ccatgatttg agcagggcaa
     5281 cgcggattga tacaacgtag ggccacttca tcttcaaagt gcaacaagtc agagttacaa
     5341 cttggacagt ttgtagggat atctagtttt tcttcagaaa cccgtttgga ctctaccaca
     5401 cgtaaaacgg cagggatgat gtcaccagcc ttatatacaa tgaccgtatc gtcttttcgg
     5461 atatcttttt cagcaatata atctacattg tgcagggtcg cacggctaac agtcgtaccg
     5521 gcaagttgta ctggtgttag attagcagtt ggagttacaa caccggtacg gccaactgtc
     5581 cagtcaactg ataagagttg agcttctttt tcttcggcag ggaacttgta ggctactgcc
     5641 cactttggag ccttaactgt aaaaccaagt tcttcttgac ttgctaggtc gttgaccttg
     5701 attaccactc catcaatatc gtaaggcaga ttttcccgtt cctgtcctac ttcttggata
     5761 aaattccaga tttcatctat gttttcagcc aagattcgct taggattgac cacaaaacct
     5821 agttgttcta ggtacttcaa acccttttct tggctatcac gagttgaagg gctggcttct
     5881 tgatagagaa acgttgcaag attacgcttg gcaactactg ctgtatccaa ctgacgcaga
     5941 gttcctgctg ccgcattacg aggattagca aattcaggct ctccattttc ttggcgcact
     6001 tggttaactt ggtcaaagga agcgcgtggc atgtaacatt ccccacgaac tgtgatatct
     6061 agttcttctg gcaaagtcaa agggatgtcc ttaacacgct tgaggttttc tgtgatattt
     6121 tcaccaattg aaccatctcc acgtgttacc ccagcaacca aaatcccctt ttcataagtc
     6181 agcgagatag ataagccatc gattttcagc tcacaaatat aggtcggatg agccacttcc
     6241 ttacgaacac gcgcatcaaa agcatctagc tcctcacgtg aaaaagcatc ctgcaaacta
     6301 taaagaggat actgatgact gtatttttca aaaccatcta aaaccttgcc accaacacga
     6361 tgagtcggac tgtctgctag cacttgctct ggataagcag tttctaactc gaccaactca
     6421 cggtaaaggc ggtcatactc actgtctgca accgagggat tatcgctggt atagtactca
     6481 gtcgcatagc gattgagcaa agcgactaac tcattcattc ttttattcat aagaccattt
     6541 taccataaaa caagccctcc tcacaaacga gaagggcgga aaaaacactt agtttgaaat
     6601 tatttttgaa actcaagcaa ccttatatca atttttcaaa atgagttcga acataaataa
     6661 acgatataca agacaagatg ataacaccac ttccaattat caggaaagaa gagagatgta
     6721 cacttggcaa gactgtcata aatccttttg caataggcat aaatagaata gctaaggtaa
     6781 aaattgtact cagtactctt ccaagaaatt cgctctcaac cttggtttgt acttgagtaa
     6841 aaaagtgaat attaaaaatc gtcataaaca attcacaaac taaatttcca gaaaaggaaa
     6901 gaaaagttgg aagtggtaat cccatcataa aaactccgac acctgtcaaa gccagtaaaa
     6961 tcaaaagatt ataaatatta gctttaattt tactagctag aagagcccca atgatggaac
     7021 caatagcccc catagttaaa atacttgcat aggctccttc tgacccgtaa agctgattcg
     7081 aaaagggaag tagaaattca aaagctgcaa aaaagaaatt aacgctggaa gctaccagca
     7141 aaaggaagaa aatttcttgc tgatgccaga tatagtgtaa cccatccttg atatctacaa
     7201 aaatatctct cccagtaaaa gcctttttct cttgaacttt tgcttcctct tttggaagga
     7261 aagccactag aacaaaagca atgaaaaaag tcagcgagtc tagcagtagc gtcatattga
     7321 gacttgcaaa ctgtaaaaca aggaaggaaa gaacaggaga gctaacacct acaacctgca
     7381 aaaccagctc taagcgagaa ttatagatca caatctcatc tttctccacc acttcagtta
     7441 tgatagcttt attggctgtg cgagaaaagg caaaagcaat agcctgcaca atgttagcaa
     7501 caatcaaagc gccaatcatc cagctatcat tccttatgaa agaaatagcc agacaaagaa
     7561 tcccacaaac aagatctgcc gtcattaaaa tcttacgacg agaaaaacgg tctgaaataa
     7621 ctccgccaaa gggattgacg agaatagatg tgacgagctc agaaatctga tacattccta
     7681 aaactgtctg tcctatagtc cccatagaag ccaaccagac actatttcca taatcataga
     7741 gcatatttcc cattttattg atagccccac ggctaatcaa ctgcactgca tagcgattca
     7801 tattaaagct cctctcaaat tttgaaacta ttgtatcaaa accgaaagga gctttttatt
     7861 ttttccctta tttgggaaaa ttaacttttg acaaattttt cgtagtgttc ctgataatag
     7921 gctacttgct ctggaagacc taacacatca aaaatatgca tggcctcttg catctgctta
     7981 cagccttctt tacactgtcc tttttgatat aaggcaaaac cttttaaata atggaaaaca
     8041 ttacgctcat aaagcttaat acctttgtca ataatcttct ctgtataagc ctcaaaatag
     8101 ttggcattat aaaaagaaga atgctctaaa caatgctggt aacaattgag ggccaaaatc
     8161 aaaactaatc tcttatggcg actaatctct tggtaaaatt cctccctctc cataacttct
     8221 ctaccaatcc gagtgacata gtctacatcg tagaaactat agaggttacc gaaaagaatc
     8281 aactcataca tggtccattc ttctgttttg aagagataat ctgctacctt atccaaatca
     8341 tcctgcttca tatcataagt cgcatctctt tgacaaatca gaccttgtag caaaatccag
     8401 ttcagctcaa aataaaggga agtcgtcgaa ctcttagact tttcaagttg ttctctttga
     8461 agcttttgaa aacctgcaat atcgtttgaa tagtaaagtg ggataatctg tgccatcata
     8521 gacacatgtt catgattatg aaaattcctt gccttatcca tgaaattttc gattgttaca
     8581 tgaatgttat ccaaaatctc aaagaaacgg gagactgcca ggtcagactc cccaagctca
     8641 aagcgagata actgagaggt agagcaggat tcgcctgctg cttcctttaa agaataattt
     8701 ccacttgttc gaaattcacg aaatactttt ccaagatgtt ccatctttac acctgatctg
     8761 ataattcttc ccactcaagc atagcttctt cctgacgatg gctgattttg tccagctcag
     8821 cctgtaattc catgagtttg tcggcatcgt ttgtttccaa catttgttca gaaatggctt
     8881 ggctttgact ttctagctct tcaatttcag cttctagact ttcgatttgt cgcatgagtt
     8941 tgcgaacttc tttttgactt tctttctggg cctgatagtc attgactgga cttgcttcct
     9001 ttgcttgatt gctagttgaa gcttcctcag tctgactcat ttctgctgtt gctttcttct
     9061 caacatagta gtcgtaatct ccaaggtaga gagttgaacc attctcagac aattccaaaa
     9121 catgagttgc cacacgattg ataaagtaac gatcatgact gacaaaaagc aaggtaccat
     9181 caaagtcaat caaggcattt tctagcactt ccttactatc aatatccaag tggttggtcg
     9241 gctcatccag aatcaaaaag ttattgtttt ccatagacaa tttagctaaa agcaaacgag
     9301 ctttttcgcc accagatagc atgccgactg attttttaac atcatctcct gagaaaagga
     9361 aggccccaag acggttgcgg atttcaactt ctggtgtcag tttgaaatca ttccagagtt
     9421 catccagcac cgtattactt ggtgtcagct tgctttgggt ttggtcatag taaccaacct
     9481 caacattagc gccaaagcgc ttttcacctt tgataaaagg aatctggtcc acaatagact
     9541 tgataaaggt tgacttgccg ataccatttg gaccaacgat agcgacagca ttcatcttac
     9601 gaagatctag gttgataggt tgtgacaaaa cttccccgtc ataaccaata gcagtatttt
     9661 caacagtcaa aacaacattg cccgacgttt tttcagactg gaaggtcatg ttggctgctt
     9721 tcttgccagc ttcaggcttg tccaaacgct ccattttttc tagttgttta cggcgagatt
     9781 gagcacgttt ggtcgttgaa gcacgaacta gattgcgatt gacaaagtct tccagagcag
     9841 cgatttcctt ctgttgcttt tcatagtttt ttgcctcagt agctagcttt tgctccttca
     9901 actcaacaaa acgagagtaa ttccccacat agcgatccaa ggaatgcttg gtcaaatcta
     9961 gcgtaattgt cgcaaccttg tccaagaaat aacggtcgtg gctgacgata atgagggcac
    10021 cgctatagtt taccaagtaa ttctctagcc aggagatggt ttcaatatcc aagtggttag
    10081 ttggctcgtc caagaccaag agattgggct tttcaaggag cattttagct agagccaaac
    10141 gagtattttg accaccagaa agctcagcaa ttttcatctg ccacatagac tcgtcaaact
    10201 tgaatccatt caaaatcgct cgaatatcag cttcataggt aaagccacct gcttggcgaa
    10261 aattttcaga taagcggtca taatctgaca tcagtttatc caaatcctca ccagactttt
    10321 cacccatctc cagctccatc tgacgcagtt gtttatctgt ccgacgtaag tcatcaaaga
    10381 catgaagcat ctcatcatag atggtatttt cagactcaaa acggctatct tgagctaggt
    10441 aagacagaga aatatctttt ttcttattga tttctccact agttggctcc tcttctccaa
    10501 ctaaaatctt caaaagagta gacttacctg caccattttt cccaacaagg gcaatccgat
    10561 ctcgttcatc aacctgcagg ttgatattat cgaaaagaac ctctcctgca aaagaacgtt
    10621 caattttatt agcttgtaaa ataatcatac aagtagtata gcatgtttcc ctaaggcatt
    10681 caagataatc gtaagtcttt tagtacaact tttataacat aaaataaact aaattatgta
    10741 tattttatat tagattcctt cactatcttg ttggattttc taaccagcta atcttgtttc
    10801 aaatagttat cgcacaagcc tattatttaa ttcttttcat tatttacgta cgc
//
LOCUS       DBERXF010000057        10381 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.57, whole genome shotgun sequence.
ACCESSION   DBERXF010000057 DBERXF010000000
VERSION     DBERXF010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10381
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.57"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(77..568)
                     /locus_tag="ACL8JK_001936"
     CDS             complement(77..568)
                     /locus_tag="ACL8JK_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786754.1"
                     /translation="MKFQTNNSLYKLMNLIIYLFLLYLFIDLLMKSGILDEQIDKLSE
                     LSNLFTIKIETILTVISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITL
                     SFSILLCYLFNPSDIKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSII
                     NSF"
     gene            complement(549..1145)
                     /locus_tag="ACL8JK_001937"
     CDS             complement(549..1145)
                     /locus_tag="ACL8JK_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS1786755.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            complement(1142..1624)
                     /locus_tag="ACL8JK_001938"
     CDS             complement(1142..1624)
                     /locus_tag="ACL8JK_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HGS1786756.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
     gene            complement(1621..2753)
                     /locus_tag="ACL8JK_001939"
                     /pseudo
     CDS             complement(1621..2753)
                     /locus_tag="ACL8JK_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698829.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2760..3056)
                     /locus_tag="ACL8JK_001940"
     CDS             complement(2760..3056)
                     /locus_tag="ACL8JK_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HGS1786757.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(3587..4480)
                     /locus_tag="ACL8JK_001941"
     CDS             complement(3587..4480)
                     /locus_tag="ACL8JK_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1786758.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(4501..4695)
                     /locus_tag="ACL8JK_001942"
     CDS             complement(4501..4695)
                     /locus_tag="ACL8JK_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786759.1"
                     /translation="MKKVLKYFLVFVFLFLMNIFIFKILATLGFQLIMSEKSYIVLPL
                     FSLIVLYMIDKRIRKKKKSL"
     gene            complement(5106..5231)
                     /locus_tag="ACL8JK_001943"
     CDS             complement(5106..5231)
                     /locus_tag="ACL8JK_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGS1786760.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            complement(5234..5464)
                     /gene="blpU"
                     /locus_tag="ACL8JK_001944"
     CDS             complement(5234..5464)
                     /gene="blpU"
                     /locus_tag="ACL8JK_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HGS1786761.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAVGGAILGGVAYAATCWW"
     gene            complement(5667..5957)
                     /locus_tag="ACL8JK_001945"
                     /pseudo
     CDS             complement(5667..5957)
                     /locus_tag="ACL8JK_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(6003..6236)
                     /locus_tag="ACL8JK_001946"
     CDS             complement(6003..6236)
                     /locus_tag="ACL8JK_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGS1786762.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(6242..7234)
                     /gene="plsX"
                     /locus_tag="ACL8JK_001947"
     CDS             complement(6242..7234)
                     /gene="plsX"
                     /locus_tag="ACL8JK_001947"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGS1786763.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLVADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(7231..8001)
                     /gene="recO"
                     /locus_tag="ACL8JK_001948"
     CDS             complement(7231..8001)
                     /gene="recO"
                     /locus_tag="ACL8JK_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGS1786764.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(7998..9167)
                     /locus_tag="ACL8JK_001949"
     CDS             complement(7998..9167)
                     /locus_tag="ACL8JK_001949"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS1786765.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            9316..10326
                     /locus_tag="ACL8JK_001950"
     CDS             9316..10326
                     /locus_tag="ACL8JK_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HGS1786766.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
BASE COUNT         3345 a         2196 c         1524 g         3316 t
ORIGIN      
        1 aatataagaa ttacaagtta acaaaaccga aatgatttca tatcattatt aagtaaagaa
       61 aaaaatttta gtatttctaa aaactattta taatagacat tatagcatta aataaaaatg
      121 gtacagaaaa cactactgtc aatcttaaat ttttaaatct cgcataattt gttatcccaa
      181 ttagtaatac tgtcaatacg ctgaaatagg caaactttat atccgatgga ttaaataaat
      241 aacaaagtaa aatgctaaaa cttaaggtta tatttttaga taaaagaata tctccaaagt
      301 tcctcttatt cttatcaaaa aataatgtaa tcagaaagag agaaaatcca tattcaataa
      361 gagttgctat aaatgtgaaa acaacagaaa tcactgtcaa tattgtttct attttaattg
      421 taaaaagatt agatagttca gataatttat caatttgttc atctaaaatt cccgacttca
      481 tcagtaaatc aataaacaaa tataaaagaa aaagataaat aatcagattc attaatttgt
      541 ataaactatt atttgtttga aatttcataa acccgtcctt cctctattaa aatcctttga
      601 gatttgctaa tcaattcttg attcaataaa ttatgagata catatataat agtagagctt
      661 tctttcatgg aaattaagcg tttagcaatc atatcaatac ttcttgcatc cactgttgat
      721 aaagtctcat caataaaaat ataatcccaa tttttagcaa aaattaagga taagcctaat
      781 ttgaattttg ttccagtaga tgctgtcata tagttatctc cgattttatt atcaaaaaaa
      841 gtattaattt gttctttatc ctcaaatgat agatggattt gaaaagaatc acacaacaac
      901 tgcaaatttt cttctatagt aaatggaaca accccaagct gattggtatc aaggtatagt
      961 acatctttgg agacacaatt ctttaaacca ctatcaaaag tctctagccc agctaaaagt
     1021 tgtagaaggg tgctctttcc tgaaccattc tctccttcaa ctctgtaaat tcccttatca
     1081 atctctagtg atatattttt caatatacat ttatcataac ttttagattc attttcaatt
     1141 ttcataattt aattccctct atcaacgctg ctaaaattaa taaaagataa gaaatgatat
     1201 accattttaa attacttttt atataaataa gtatattttt aattccccta tccttcaata
     1261 atcggtataa aagatactga ctcatacctt gataccaaat aaaattcggt atttcaataa
     1321 gagcatgagg taatattcct tttattgtag ctactattcc aatcatctga ccagatatac
     1381 ccaattgtat tcctaaagat agcaaatcaa aaagttgcaa taagggcgaa atcggaaaac
     1441 agaatagata tagcaaaaaa tttgtagaat ttgcctgtaa aactgtcaat gtaaattgta
     1501 attccagttt cggaggtata gtagcaaaag tctcattttt taatataaag cttaaaagta
     1561 aacctagtaa aaaacagact atacaaaata acacatagta aatcagaaaa ccactttttc
     1621 tcatctaatg ccccctacta aaattacaaa tattatcaga aaacaatata aaaccagaaa
     1681 actccatctc aataaactaa ctgtaccttt aattaaaaat agagctttct tataatagac
     1741 ataggctata aaataattga atggaatcaa taacaaattc aacaaaatac tttttatatc
     1801 attactataa cttgtcaccg gaatcaaaca taacaacaat gaaaattgta agaaagagat
     1861 taaatgcgtc aacatcatta gttgtgcatt cttaaaaaag aaattcattt tagaatgatt
     1921 aagagcagat aattgaagta aagctagatc taccccaatt gaggatttat gattccctat
     1981 tattgcctcc attaatgtaa tatatattga ggtataaaga aataatattg gtatttttgt
     2041 gtcatcaatt gataacatcg tcatcatata ccaaaataga taggaaagaa gaatactaat
     2101 caaaataaaa gaaaaagtta accctttatt taaccaacaa aaacgaagca atataaatag
     2161 actgctacga aatctttttt gactcattcg actgctttta aaatagaaat tactcgcatg
     2221 attatctaat atccccatga ctaaaataaa ataattgagt agtatgacat aaattacaac
     2281 ttgtccttgt tctatagaca atagtcctat agataaaaat aagaacaatt tacttataat
     2341 tgaaaacaaa ctaggtagaa ttaaagaaat aatttgaata gctatcaaac aaagagtaat
     2401 ggataaataa aaatatccaa taatatctag aaaatacaaa ataaataaat gaatgattgt
     2461 aaaatttgga aagaataata tttcttgaca atggcaagaa gatagagaaa aatatagttt
     2521 ttccttatat agaaagtatt tattttttta ctttggatag gcagtttcat attataacga
     2581 ttcaaagtag cgtaatctac taccaaaaaa agtaaaaata atttcccttg aaaaggaaga
     2641 tagcttttaa aatagattga caaacttatg ataacaaaaa acaaaagggt tatcccaata
     2701 aaattaagat aacctaaaat actttcacat tcttttttag aaagtatttt catctagttc
     2761 taccatagag ctgctttagc agcacctttc tttttcaata tataaagaac tgttgctgca
     2821 atacccgaac caatagaacc tactcctgtg attgcaccta caattgaaat tactgctgta
     2881 actgtactat aagcactaat caaattgact acagtagcag cagcttttgt cgaaattcct
     2941 aatgtcccag ccaacatagg aaaagaaaca acacctaagc ttaaccaact aatgactgct
     3001 aacattgctg aaacaataag aaatttatta tgaaattcca ttcttttaga tttcatttta
     3061 gtgtactcct tttgtatatt atgtatgttt tattgagagt taattcgcac atgttgtatt
     3121 cctaactctc ttcaaatgtt cgtctatatt ttatactact tttattaaca tatctataat
     3181 aaataaatta ctactacatt ttcctagatt atcaaattac ttttatatca ctaagactca
     3241 ataaaagata atgtctattt aacttttata cgattactac cttcttttta gtttacactt
     3301 cctacatcat aaataaacat actcaaccct cacaatctcc aaataactct tctatatcat
     3361 tgaaaattga gtttcatcct ctatactaat gtaggacatt cctttaatcc aatataagaa
     3421 taccttgttc cattaatctc tacccgatat tatagataga accaaattcc tatacttaaa
     3481 aggacaaata acgttccaac cataataaac ctcctttctt tttgagaacg ttttctttat
     3541 aggtttagta tagcaaaaac atgaaaaaaa caacatgact tagaagtcag gttgttggga
     3601 aatctatctg tttttctgct aaaattctct gaactaatac ctgatcgtct agcaattctg
     3661 ctagagaaat cgccttttca tagaaacttt ctgcctctaa aatattcttg tctacaaata
     3721 aagcatattt tgcctttagc aaaaatagat gaggtcggta aaaaacatgt cttgttttag
     3781 caataatttt ctcaaatgtt tgaatatata tcagactatc ttctgtctga atttggataa
     3841 ataggctcag aagaactttt tccatttgaa ctaggctagc cttatcttca tattctgaac
     3901 atagcaatac tttttgagct aactcctcaa aatgttcttt atcttctaat cccatagcac
     3961 aacaaaagaa atacaattca ataatcaaca aatcatttac agaaaaatat ttctttttta
     4021 ataactgctg gaaatattct tccactaacc ctaaaccgta ggtcacatct gaactaccat
     4081 aaatatcaaa acgagcttgt gtcacatcca caattaactg ctcttcctca ggcaaattct
     4141 cataatagtt ttcatatatt tcctcaagta tagcttcttt tcgttcgatt cttcccttat
     4201 cagcgtaggt ttgagaatga atcagctcat ctttgagttt taggaatcct tttggaatct
     4261 ctataacctt aacatccaca atattctgta atgatactcc aagtttatcc gcaatcaata
     4321 ataatttagg aagtgttgct aaagcttgcc cattttcaat acgtgctagc tgacgaatcg
     4381 tcaactctga ttcatcacca caaatatcta tctgagtttt tccacaagat cgcctaatag
     4441 ttttgatttt ataaccaatt tcacgtttca actcatccat agtaatactc cttaagttga
     4501 ttacaaagat ttctttttct tcctaattct tttgtcaatc atatataaaa cgataagcga
     4561 aaacagcggt agaacaatat aactcttttc actcattatc agctgaaatc ccagggttgc
     4621 tagtatctta aagatgaaaa tattcatcaa aaatagaaaa acaaatacta aaaaatattt
     4681 taaaaccttc ttcatttctt ttcttcaact ttcctaattt ctacacctat tttatcgaaa
     4741 atatatataa aactccaaat aaacacttca actgcacttt ttttggcaaa aaatagacag
     4801 aacaaacatc ctacctacta aaaatatgat atgaaaggaa aatgattttt tactgacacc
     4861 ctaggcaagc ttgggacaaa taaatcattg atagcaacat ttacgacatc ctatttaaag
     4921 ttccttcaat ttctaatgtc cccgctattt ctaagccacc tctggtatga tctattccta
     4981 gtcagaatag ataacaccgt tctaaattac gattcatagt tactcctttt ttgactcgtt
     5041 actataagac tcctatttac atgcgcaaaa taattttgat tcagattcat catttatagt
     5101 tttgattatt ttttaacaga tttttctgtt ttcttctccg aagactttaa aaattttttt
     5161 ctaattaaat catccatata aggaccaaat ataccaacta ctaaaccaat aataaaactt
     5221 ttaaaatcca taattaccac caacatgtcg ctgcataggc cacacctcca agtatagctc
     5281 ctcccacagc accagttgct gcaccttgcc atgttcttgt tttaattcct agctgaagac
     5341 ctcgtgctgc tcctcctcca acacctgctt tggcaaaatc tccccaattg catccgccac
     5401 cttcaacgca agcaagcatc tcagtatcca taatttcaaa ttgtgacatc gtttttgtat
     5461 tcataacgaa tacctctttt ttatttttaa tatttgtctt gttacaaact tgacaagttt
     5521 agtataacag tatctattaa tttttttcat ccaaatcttg aattggcatc gaaacgtctt
     5581 gaattagctt ttttgtttca aaatcatctc tatttttaaa aaagatgttt tctaatcact
     5641 tttttactat tagacttcct gcaaaactag aatcctagtt catgattgat aataccagca
     5701 atcaaattca ttcgtaatcc gaagcgttta cgatgatttc gataggttgt tgaaaacatt
     5761 ttaaacgttt ttactttggc aaagatattc tcaaccttgc ttctctcctt agatagcgca
     5821 tgattacagg ctttatcttc aactgttagc ggcttgagtt tgctggattt acgtggagtt
     5881 tgtgcttgag gatatatctt catgagccct tgataaccac tgtcagccaa gattttacca
     5941 gcttgtccga tatttctcat ttctaaaaac catctacttc cgttgacttg gaactccgat
     6001 tgctattttc cttgaatgat tttaaccaca tctcctacgt tttggagttg gtcaatttct
     6061 tcatcgctga tttcgatact aaattcatct tccagagtca agataaactc catcaagtca
     6121 acagaatccg catccaaatc gtctttcaga ctcaaggatt ctgtcacgac aaagtcctct
     6181 ccctgtcgct cttggataat ggtcacaata cggtcaaaaa tttctttttc tgtcatctct
     6241 tttattctcc tgaaaattca cgcgcagtct gggcaactac gtctgtttct agcatggtac
     6301 gaatctggcg aatcgtacta taaacagcct tggcatcgct tgagccatga gtcttgacaa
     6361 caggtgcctt aacaccaaac aagaccgctc caccaacatc tgaataattg agctgttttt
     6421 tcaaacctct gaggctgtcc ttgagaagga gggcacctag tttcgctcga agaccaccac
     6481 ctgtaatagc tgtcttgagc aagcccatga ttcccatagc tgtcccttcg atggatttga
     6541 gcacagcgtt tcccgtgaaa ccatctgcca caacaacatc tgcaacgcca ttcatcaaat
     6601 cacgcgcttc cacatttccg ataaagttca aactttcatc agccactagt aattcataag
     6661 tttccttacg aagcggatcg cccttgctac tctctgttcc gttattgagc aagccaacac
     6721 gtggttgcgc aatgccacga acatttttag catagaagga tcctagaacc gcgtattgat
     6781 ggaggtgctg ggctgtattt tccgcattgg caccgaggtc tagcatgtca aatcccttcc
     6841 catctacagt cggcaaagtc gacataagcc caggacggtc gatattcttg atacgaccca
     6901 cgatgaagaa tccagcagcc aacaaggcac ctgtattccc agccgaaagg acagcgtctg
     6961 cttcaccatc tttgacagcc ttggctgcca ataccatact ggcatttttc ttattcctaa
     7021 tagctctcgt aggttcatca tccgaatcaa tcttctcatc cgtatggata atgctgacgc
     7081 gctctgtcgc tgtcagatat tgcttgattt tagcttcatc tccgtaaagt tgaacctcga
     7141 tatctgaaaa gtcagatagg gcttgattga caccctcaac aatggcctga ggtgcgtaat
     7201 cgccccccat ggcatctact gcgatttttt tcatttcttt tcctctttta gtaattgtcc
     7261 ccagtctgct agggaatcaa taaatttctt tgattttagg tgaatcccaa cgtactcttc
     7321 atataattga tccataaatt ggcgtagctc ttgcttgatt ccaggcttga gcgaaatggt
     7381 ctccaaagtc tcaaaatcaa tagcttgaaa ttgattgagc agatagggga tattgggatt
     7441 gagatgacaa cgtctcttat cctcatgata atgctctgga cagaggcagg ctccatattt
     7501 gaaagaaaag tcaaaagcct gaccaacccg atggcagaag acacactcat taaaattgag
     7561 gctgattcca aatcgagtca aaatttgaat ttcaaaaata ttggtcaaaa cctgataatc
     7621 caagcctgct tccatcaact ccaaagtctt ttgcaaaaaa gcaaacaagg gagcatcctg
     7681 ctgattgtcc tgcaaactag catctgcaag agctgccaca taggtcgcat aggccatgac
     7741 aaagaggtca ctattaatct tgggaaaagt catgacctca tgatagtctt cgatgtaact
     7801 gagtccgtca tcattgattc gcaagagaaa tcgtgccagc accaagggct gaataacagg
     7861 cgccagctta gactgaccag cgtgtttgac aaaaaacatg cgtttgccaa cctgctctgt
     7921 aaaaattttg acgagcttgt catcctcacg aaaattgcga ttgtaaagca ccaagccttg
     7981 actcgtgata gactgaatca tgcttctctc atgtactcct caagtcgttt catggcttct
     8041 ttgatagtct ccatgctggc tgcataagat aggcggacgt agccttcccc gtaacgtcca
     8101 aaggctgcac cagggataaa ggcaacggcc ttcttctgag caaaatcctt cagaaaagca
     8161 aaggagtctt gattgtagcc cgctggaatt ttagcaaaaa tatagaaggc accgtctggt
     8221 ttgataatct caaaaccaag agcagtcatt ttttcgatga tatagtcccg acgttggata
     8281 tattccttct tcatgggctc cgcatcgttt ttaccagccg tcaaggcttc taccgcagca
     8341 tgttgcgcca tggtatttgc ggcagtgacc aagtactggt gactcttgat taactgggct
     8401 gtgaaggtcg caggagcgaa aatcagcccc aaacgccaac ctgtcatggc atgcgattta
     8461 gacaaaccat tgataataat agcctggtct ctcaacatcg ttcctagaga cacatgggct
     8521 tcgcctgtgt aggtcaattc tgagtaaacc tcatcacaga caacaaaaat ttcgtacttg
     8581 cgtaaaacag ctgccaaggc ctctaactgc tctcgactgt aggtaattcc tgtcggattg
     8641 gctggatagt tgagaataac cgccttgagc ttatcaccct gctccaaaat ggccttctcc
     8701 aacatctcag gagtcaagac aaaaccattt tcagtcgtat caatctcaac aatttctgcc
     8761 ccaactaagt taacaatcgg ttcatagcct ggataagcag gagctggcaa aagtaccttg
     8821 tctccctctt ccaaaatagc cgtcaaagtc gcagataaag cctctgtcgc cccaattgta
     8881 accaagattt cattttcagg agcatagtcc agttggtact tttccttaac aaagtcactg
     8941 gctgcctgac gtagagtcag cagaccactc atccctgtat agtaggattg gttctgatca
     9001 atcgctcgct tggccgcctc cttgacatgg tctggcgttg taaaatcagg ttcccccaag
     9061 gtcaaacgca agaccccagg aatctccgaa ataacctggt caaactgacg aatcaacgaa
     9121 acttgaattt tatctaactg tttattaaag cgcttagtta agtccataga tacctcctac
     9181 tttcaaaacg tatctctatt atactacaaa agccccccga ccgcaaaaat acattagaga
     9241 atagctttcc actttctatt ttacttttcc tgtttatagg tctataatgg taatagattt
     9301 tatttggagg tttttatgtc atttctatca aaaaatggag caggtatctt ggcctgcctt
     9361 ctcatttcca tcctatcttg gtacttagga ggattcttcc ctgtgattgg cgcgcccgtt
     9421 tttgccattt tcataggcat gctcctacat ccctttctct cgtcctataa acaactggat
     9481 gctggtttga cctttagttc caagaagttg ctccaatatg ccgttgtctt gcttggtttt
     9541 ggtctcaata tctcgcaggt cttcgcagtt ggccaatctt cactccctgt catcctgtcc
     9601 actatctcaa tagctctgat tattgcctac ctcttccagc gtttctttgc actggataca
     9661 aaactggcta ccttggttgg agtaggttct tctatctgtg ggggttctgc cattgcagcg
     9721 acagcgcctg ttatccatgc taaggaaaag gaagtagccc aagccatttc cgttatcttt
     9781 ttcttcaatg tcttggctgc gctcatcttt ccaaccctcg gcacctggct tcatctatcc
     9841 aatgaaggct tcgccctctt tgcagggact gcggtcaacg acacttcctc tgtaacggct
     9901 gccgccagcg cttgggacag tctttaccaa agcaataccc tcgagtctgc aaccattgtt
     9961 aaactcacac gtactttggc cattatccct atcacgctct ttctatccta ctggcaaagt
    10021 cgccaacaag aaaacaagca aagcctacaa ctgaaaaaag tcttcccact ttttatcctt
    10081 tactttatcc ttgcctctct cctcactaca ctactcacct ctctaggtgt gtccagtagt
    10141 ttctttaccc ctctcaaaca actctctaaa ttccttattg tcatggccat gagtgctatc
    10201 ggtctcaaaa ccaatctggt cgctatggtc aaatccagtg gaaaatccat tcttcttgga
    10261 gccatctgct ggattgccat catcctcacc actcttggta tgcagaccct tatcggcatt
    10321 ttctaacact cttcgaaaat ctcttcaaac cacgtcaacg tcgccttgcc gtatatatgt
    10381 t
//
LOCUS       DBERXF010000058         9285 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.58, whole genome shotgun sequence.
ACCESSION   DBERXF010000058 DBERXF010000000
VERSION     DBERXF010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9285
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.58"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            168..854
                     /locus_tag="ACL8JK_001951"
     CDS             168..854
                     /locus_tag="ACL8JK_001951"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGS1786767.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            855..1787
                     /locus_tag="ACL8JK_001952"
     CDS             855..1787
                     /locus_tag="ACL8JK_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1786768.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1798..2727
                     /locus_tag="ACL8JK_001953"
     CDS             1798..2727
                     /locus_tag="ACL8JK_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS1786769.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLKNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            2741..4180
                     /locus_tag="ACL8JK_001954"
     CDS             2741..4180
                     /locus_tag="ACL8JK_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786770.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            4249..5826
                     /locus_tag="ACL8JK_001955"
     CDS             4249..5826
                     /locus_tag="ACL8JK_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS1786771.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKPFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            5886..7346
                     /locus_tag="ACL8JK_001956"
     CDS             5886..7346
                     /locus_tag="ACL8JK_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGS1786772.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNVEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKIIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            7368..7823
                     /locus_tag="ACL8JK_001957"
     CDS             7368..7823
                     /locus_tag="ACL8JK_001957"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGS1786773.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            8328..8777
                     /locus_tag="ACL8JK_001958"
     CDS             8328..8777
                     /locus_tag="ACL8JK_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGS1786774.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDIPKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEEIILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHKTGLLVEEPINIKKVVFKVKI"
     gene            complement(8822..>9285)
                     /locus_tag="ACL8JK_001959"
     CDS             complement(8822..>9285)
                     /locus_tag="ACL8JK_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGS1786775.1"
                     /translation="CWSPIGVGPHVHSHYIREFRYCYGAVDAHTGESFFLIAGGCNTE
                     WMNAFLEELSQAYPDDYLLLVMDNAIWHKSSILKIPTNIGFAFIPPYTPEMNPIEQVW
                     KEIRKCGFKNKAFRTLEDVMNQLQDVIQGLEKEVIKSIVNRRWTRMLFENR"
BASE COUNT         3213 a         1242 c         1728 g         3102 t
ORIGIN      
        1 gtgtattgaa tctataacag tacgccttaa atgctaaaat atttctataa attaatttaa
       61 ctttcctgat agggctgttc atatcttatt tcaattcact atataaataa aattgtagta
      121 gatgttattg aattagtaaa aaaaataaaa aaacggaggt tttctgaatg gaaactaaaa
      181 aaattaaaaa tttaaaaggt caaataattg tttcctgcca agcgttagaa ggagagccac
      241 tttatactcc aaatggagga gtgatgccgt tattagcaaa agccgccttt caagcaggcg
      301 ctaaaggtat tcgtgctaat tctgtccgcg atatttcaga aataaaagaa gaagttgact
      361 taccaattat aggtatcata aaaagagatt acgatggctt tgaacctttt atttcagcaa
      421 ctatgaaaga gattgatgaa ttagttagtg aaggagtaga cattttagct ttggattgta
      481 ctaatcgttc aagaccaggt tatgataata ttactgactt tattcatgat attaaagtca
      541 agtatccaaa ccaattatta atggctgata tttctacttt tgaagaaggg aaagtagctg
      601 ctgaatcggg agtagatttt gtgggtacga cattatctgg ttatacacca tatagcccta
      661 aaaaagataa tcctgatttt gagttagttg aaagattggt aaaagagctt gacgtaccag
      721 ttattgctga aggaagaata agtactccgg aacaagctag aaaaatgtta gatttaggtg
      781 cttacgcagt ggttgttgga ggagctatca ctcgtccttt ggaaatagcg aagaagttta
      841 ttgaggtagt ttagatgaat caagaaatat taaaaaagag taagattcaa ttgacagttg
      901 aacatattca aaaatattgg attttatatt taatgatgat tccagcaact gttctactaa
      961 ttttatttac gtatggacca atgtacggca ttattatggc ctttcaagac tttactgtct
     1021 tcaagggata tactggaagt ccatttgtcg gtttaaaaca ttttcaaaga ttgttctcag
     1081 atcctttgtt ttatagattg ttcaagaata cgttcatggt aggggtttta gactttttat
     1141 tctctttccc agctccgctt atttttgcac tcatattaaa cgaagtcaga aaagtaagat
     1201 ttaagagtgt agttcaatct attagttatc ttcctcattt tattccccta gtggttatgg
     1261 ttggtattat ttttgaacta tttggttcat atggtattat taacagttta ctttcatcac
     1321 ttggaatgga gccaataagt ttctttacaa aatctgaatg gttcttgcct ctctacattg
     1381 gttcaggagt atggaaaaca ataggttggg gttctatcat ttatatggga gcattaacca
     1441 atatagattc aactttatat gaagcagcag atatggacgg ggctaataga tggcacaaaa
     1501 tgtggcatgt aactctacca agtttaagac ctacagtagt tactttgttt atactaaatg
     1561 ctggtggtat catgcaagta ggatttgaaa aggtattctt gatgtctagt cctgcaacat
     1621 atgaagtatc tgatgtatta tctacttatg tttatagaca aggtatttta aattctgatt
     1681 tcagttactc agctgcagta ggattattta ataacatagt agctttgtta tttgttttat
     1741 tagctaataa gattgctaaa aaacttggcg aagaaggaat tgtataaggg gggtaaaatg
     1801 attttttcaa aaaatacaaa aaagagtaat agagacaaag aaaccttcgt tgattatctc
     1861 tttatattca ttttaataat aataacctta cttatgttgt atccattatg gtgggtagtg
     1921 atgacgtcac tttcagaacc agtttggcta tctaaaaacg ttgttaaatt atttccctta
     1981 aaaatagata ttactgcata taagtttatt tttggggatt ctaaactatg gcaagcatat
     2041 ggtaatagtg tattgtatgc tgcactatct acaattgtta gtgttgcggt atgtagtatg
     2101 tatgcctatc cacttacaat tcctgaaatt aggggtaaaa aattctggaa tactcttatt
     2161 ttgattccaa tgttctttag tggaggaatg atcccgcttt atatacaagt tgcaaacctc
     2221 ggtttattga atactgcttg ggctcttgtt ttacctggtg ctgtttctac atattatata
     2281 attttgttta gaacacagtt taaatcaatc ccaatggagc ttcgtgagtc tgctagaatt
     2341 gatggggcaa gtgaatttag aattttttgg aatttagtat taccattatc aaaagttatt
     2401 ttcatgatta tagcacttta ttgcatagtt ggttcatgga atagttttac tcctccatta
     2461 ctttatttga atgacgacac taagatgcct ttatctattt atttgaaaaa tttagttgtt
     2521 acaaatacaa ctgatactgc tgaattatca ctttctgcag gtaatacata ttaccaacaa
     2581 attgctgctc aaggtggagg tattggtatg cgtattgcta ttaagatggg tactattgtt
     2641 gttagtgtta ttccaattat gatgatttat ccatttattc agaaacattt tgttaaggga
     2701 atcctgctag gttctgtgaa aggttaataa ggtaattatt ttgcaaaatt taaaaaaata
     2761 tcttttatta gatagcggtt tagtagttgg gtatacatta gaaaatgctc aattaaaatt
     2821 aaataagcta aaaaaagata ctgaaaacaa tccactattt ggtgaagagt attttgccga
     2881 aaatcctaaa ttatgggaag ttcgttttga taattcatat ccaaacgtta tctatgataa
     2941 agaattgaaa ttatatagat gttggtatca aacatttgtt agtgatgaag caagcgaaga
     3001 gactccttta gcagaacgtg gagagaagga atacattgtc aagtcatcta gaatgacagc
     3061 actttgctat gctgaaagta aagatggagt aaaatgggaa aaaccaaatc tcaatctagt
     3121 aaaatttaaa ggttcaaaag ataataatat tgttctgatg catgcacacg gtgcaggtat
     3181 catgctagat gaacaggagt tggatcctaa gaaacgatat aaattagttt caaaattaga
     3241 attttctccg aatcttcatt acatggttgt tgttttttca gaagacggta ttcattttga
     3301 cgaacctatt ccatggaaaa aatggaatcc tgcagcagat agtcataatt ttccatttag
     3361 agatccaaaa actggtaaat acgctgttat tacaagaacc tgggcaaata acgtacgtct
     3421 aagtgcaatt actttcagtg atgattttat taattggtca gaacctaaag aaatccttag
     3481 gggagatgga tttgaagatc aaatttattc tatgccagta atttcatacg cggatatcta
     3541 tttaggtttt gcttcaatgt accacgaagg cgacacttta aatgaaaact atgataaagt
     3601 agacttagaa ttgaaattct ctgctaattt ggaacaatgg gatagtgtat gtaagggcga
     3661 ctatctcatt gaaaggggag gtggagtata cccgcagaat gctgattttg atgctagttg
     3721 tattttcacg gctgctccaa taattgaaga tgataagatt tggttctact atatgggtgg
     3781 aaatggtaat cacactggct tccgagaaag ttcattagct agaggatata ttaagaaaga
     3841 ccaatttgct tattatacta ataagagaga aggaattcca gctaaaatat ctacagttag
     3901 cttccaaact tacgatgatg aaatttatat cttagctgat attcctgaaa atggttatat
     3961 taaagttgcg gtaggtacta aatacggtaa tgcttattca gattttggtc aggaagatat
     4021 ctctcttgtt caagtttccg atggtaagta taagttggaa tttaataaaa aatctatctt
     4081 agatttaggt aattctccag ttgcgttcaa atttgaaatc gagaatgcaa aattgtatgg
     4141 tattgaaggt agtattcagc aacactatct caaatattaa ccagaataat tcgttaacaa
     4201 ataatctcta tattagtgga gatagatata taaaatggag gtcttattat ggtaaagctt
     4261 aataaggtat taaaagggag tgttgcattc ctgagtgcaa gtttattgct agcagcttgt
     4321 ggcaataacg ctaattcaaa gcccgctgaa aaaacagctg atggtaaaac gaaaatttcg
     4381 tttctatcta catggcaaat taatgatgtt cgtccgccta aagatgaaac acttgttggt
     4441 caatggttag aagaacagct aggtattgat attgatcttg taactattcc tggcgaggga
     4501 gtaagttcta aagtaaattc tcttattact agtaaccagt taccgactgt tttgttgaca
     4561 acaggagata agagtgatat cgctggtatc aacaaacttg gtaaacaggg tgcattctta
     4621 gatttgtcac aacacatgga caaactacca aactataaga agtaccttga aaaaaataat
     4681 gcattagctc aaatagaaga tgatgaaaaa catatttatg ctttcacaaa attctttact
     4741 gatgagaata tcatgtatac tacaccaatt ctgagaaaag acttacttgt tggttcagaa
     4801 tttgaagatc tttcaaaaat taaaactgtt gatgactata caaaagtttt gaaatatttg
     4861 actgaaaaac aaggttctcc agcatttatt caacgtaatg gctatgaagg cttcatgaag
     4921 cgagttacac cattgtggaa tttaagccat cgtacatact atgactatga atcagattca
     4981 tataaacatc cagttgaaca acctcaattg aaacaattcg ttgaatggtt gaaagaatta
     5041 cgtaaagata acgtacttca ccctgactgg gcagttatga aagatgaaac ttgggaaggt
     5101 ctattggctt ctaacaaggg ttcattcact gttgaccgta tgaatatcat tggagataat
     5161 aactttgata aaccatttga ttggcagcca cttgtttatc cagaaattaa tggaaaacgt
     5221 tatttgcaac cgaaaacacc gtacatttct gattcaggtt gggtaatcaa tgccaatgca
     5281 ccaaaagaag aaattgataa agcgttagaa ttctttaatt tcttatacgc tgatgaaaat
     5341 caagaaaaac ttgctattgg atttgaaggt aaaacattta cacgtgaaaa ccctaatact
     5401 caagcaggta ttaaatggtt gattcaaatt tacggtgaaa atgctggaaa tgataaagca
     5461 gaactgctgt ttaaacatgg taaccaagca tttactcgcg ttcaaactaa attagatatt
     5521 gaggcacagc caggaacatt ccctaaagtt atgtatgatc aagtagataa aattaagaaa
     5581 gatttaggtg gttttagacc agatactccg gttctttcct ttacaactga agaattagat
     5641 gttttaacta aatctgaagc aggattaaat actttctttg atgaaaatat tattaaattc
     5701 attgaaggac aaagagatat gagtgagtgg gattcattta tcaatgaagc taaatctaaa
     5761 gacttggata aagttacaaa agtatataat gatgcctaca aacgtgtcaa agatagaatg
     5821 aaatagacta aatggtagct ctctggtttt tcagagagct actactgcct gagggggagt
     5881 aagctttgta tgatgtagta attataggtg caggaagttc gggcgcattg gctgcaattg
     5941 cttcggggcg tctagggtta aaaacttgtc taatagagaa gggaagtaga attggtggag
     6001 ttcctattaa tacactaatg gggtcatttg ctaatctata ttttgatgat tctggtagag
     6061 taaatgcaag taaaattgtt ggggaattaa tagaacgtat tatcaaaaaa ggtggtactg
     6121 tctttaactc tatggaagaa ttgatgaatg taaatgattt ttatcagatt acaattccct
     6181 atcaaccaga agtttatgaa tcggttttaa ctgatatgtt gattgagtct aaagttgata
     6241 ttttactaaa tgttgaagtt aataatatta tttatgatag taaaaatatt aaaagtcttg
     6301 aaattttaag taatcaggaa gttaaattga ttgattctaa agtttttatt gatgctacag
     6361 ggaatgcaac aattgcttct gctagtggag ctgatgttta tgaaaaaaat tcttcttacg
     6421 gttgtttaat gagagttgga ggagttgata tctcaaagat tatagaacat attgaaaaaa
     6481 caaagcagtg gaactatata gaaggatata atcagtggtt agaagaagta ttagcaaatc
     6541 gaaagtacag agccactgga gcagttttaa aagatccagt ttcttatgat catgccccta
     6601 tgctttcaaa agacgaccat tttatgaatg atgaaaaatg gaattacatt aaagaaagat
     6661 gggaaaaatt tagatttatt tacactttag aagtatcact atttaggaat gaattaaaaa
     6721 aagctgtaga atctggggat tttaattttg aaatttatca tgatgataaa tctggagtca
     6781 ctatgaatgg cgacggtata agctatggtt catggggtca aaatgtagca ttaattaatg
     6841 ttgcaaaagc atttggattc aatcccaaat atatggaaga tgaatcacat gctaatattc
     6901 tttctagaaa atataattta acatttttat cttttcttaa aaaatatgta ccaggttttg
     6961 aaaattcttt tatccttgat cagggaacta gagctactaa cagatcatgt aggcacattg
     7021 ataattcatc tatgatggac gaaattcttg attttccaat gtatacattt aagactatgt
     7081 atagctatca aactcctaaa gaaataacgt ataaatcaat tgtaggtgga aaattgaata
     7141 atttgtttgt aataggtaaa ggtgcttacc aatccgaaag ttttagatca caaattagtt
     7201 gtatgttaat ggggatatca tcagcagcag cggcaaaaac tattattgaa gataaaagca
     7261 atactctaaa cattaataga gatttgttta aatcgaactt agatatatta tttacatggg
     7321 agttttctaa ttggattact gattaacaaa taataaggga atattaaatg aatgatacta
     7381 ataaaaatca atactttgtt tatgaatttg atactagctt tgtagaaatg tcttattctc
     7441 agttttttga aggatattgt attctttttt caaaagaacc ctatccttct ttatctgata
     7501 tgccaatgga atttagaaaa gaatttttaa tggaaatgag tatattaggt gatgcgatgc
     7561 ttgaagtgtt aaatgcctat agaattaatt atgatatctt aggaaattca acacctgtac
     7621 ttcatgctca tttatttccg agatacatgt gggaagagga agagagaaga aaaactgtag
     7681 ttcatagata tgattcttca gtttttagca atcctgagtt tgaatttact atagaaaagc
     7741 atggaccaat tattaaaaaa ctgaggtctg ctattgatag acattataga gagtatcaac
     7801 aattattaga tgattcaaac tgaactccac attttcgatt agatttaata ccttgtatat
     7861 tacaactagg ttgtggatga tataattttt cgaaaaatat attttaggaa tgacttataa
     7921 agtaattata tcagaggtta ttaaatcaat ggtccaagct tatgctcctt attcttattt
     7981 taaggttgga gctgcgttag aaactgaaga taaaaatttt tttctggatg taatatagaa
     8041 aatgttgctt ttctcctact tgctgtgcag aacgagtata tttttacaaa gctgtattta
     8101 aaggagaacg ttcgttttca aaaatatgta ttgtaggcgg aaaaaaaggt attttatcat
     8161 cttttatagc atcttgcagg gtgtcttgtc aggtaatgat agaattttgt aatcttgatt
     8221 catttgtagt tatattggct agtgatgttg atacttataa agtatataaa cttaaagaac
     8281 tactaccagt tagttttaat caagaaaatt tataacagga gggaactatg gaattagttg
     8341 aatttaaaaa tggacatgtt aatacggttc atgagcatat cgcaataacg aaagtaaaag
     8401 agtttctaaa taatcatgat ataccaaaag ataaaggtgg catacataaa atttctactg
     8461 atttctttta caatataatt gatatggaaa ctacaactga agaaaataga ccgtgggaaa
     8521 gtcataagga atattatgat gtccattatc tgttaaatgg agaagaaata attttatata
     8581 atttcttgtc tcaaatggaa ttgtctgaat ataaagtaga tgatgattgg caacaaatga
     8641 atgggacagc tttatttagt attaaattaa agaaagatat gttacttttg ttggaaccaa
     8701 acgatgcaca taaaacaggc ctattggttg aagaaccaat taatattaag aaagttgttt
     8761 ttaaggtaaa aatttaactg aaagtacttt cagggattaa gaattttaaa atatttaata
     8821 ctcatctgtt ttcaaaaagc attctagtcc atctccgatt aacgatggac tttatcacct
     8881 ccttctccag tccttgtatg acatcttgaa gttgattcat gacatcttcc aaagttcgaa
     8941 aggctttatt cttaaatcca catttacgaa tctctttcca cacttgttca atggggttca
     9001 tctctggtgt gtatggagga ataaatgcaa aaccaatatt agtcggaatc tttaagatac
     9061 ttgatttatg ccatatagca ttgtccataa cgagtaaaag ataatcatct ggataagctt
     9121 gtgaaagctc ttctaaaaag gcgttcatcc actcagtatt acatccacca gctattaaga
     9181 aaaatgattc gcctgtatgg gcatcaacag ctccataaca atagcgaaat tctcgtatat
     9241 agtgactatg gacatgtgga cctactccta ttggagacca acaag
//
LOCUS       DBERXF010000059         8777 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.59, whole genome shotgun sequence.
ACCESSION   DBERXF010000059 DBERXF010000000
VERSION     DBERXF010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8777
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.59"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(394..1590)
                     /gene="tuf"
                     /locus_tag="ACL8JK_001960"
     CDS             complement(394..1590)
                     /gene="tuf"
                     /locus_tag="ACL8JK_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGS1786776.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2501..3370)
                     /gene="gla"
                     /locus_tag="ACL8JK_001961"
     CDS             complement(2501..3370)
                     /gene="gla"
                     /locus_tag="ACL8JK_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HGS1786777.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3594..4115)
                     /locus_tag="ACL8JK_001962"
                     /pseudo
     CDS             complement(3594..4115)
                     /locus_tag="ACL8JK_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(4073..5179)
                     /locus_tag="ACL8JK_001963"
     CDS             complement(4073..5179)
                     /locus_tag="ACL8JK_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HGS1786778.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEVDTNSASLTGNIVSEGRTVTLVYRESEAPTTVTVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5290..5544)
                     /locus_tag="ACL8JK_001964"
     CDS             complement(5290..5544)
                     /locus_tag="ACL8JK_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786779.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5538..5780)
                     /locus_tag="ACL8JK_001965"
     CDS             complement(5538..5780)
                     /locus_tag="ACL8JK_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786780.1"
                     /translation="MVQNEDLYKKGLNVELAHQQIKGFFEAEFKNRINGVLNTKIKNS
                     TLNRVNKKTIHQSNKNSMINLKQKQRKMLKNKAILC"
     gene            complement(5884..6728)
                     /locus_tag="ACL8JK_001966"
                     /pseudo
     CDS             complement(5884..6728)
                     /locus_tag="ACL8JK_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078372828.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            6962..8680
                     /locus_tag="ACL8JK_001967"
     CDS             6962..8680
                     /locus_tag="ACL8JK_001967"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGS1786781.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
BASE COUNT         2504 a         1796 c         1650 g         2827 t
ORIGIN      
        1 ttgatttcat attactattg tataatgctt tttgatttta gtctagtatt atactcttcg
       61 aaaatctctt caaaccgcgt cagcttcgcc ttgtcgtata gatgttactg acttcgtcag
      121 ttctatctac aacctaaaaa cagtgttttg agcagtctgt agctaacttt ctatagtaaa
      181 atgaaataag aacaagacaa atcgatcagg acagtcaaat cgatttctaa caatgtttta
      241 gaagtagatg tgtactattc tagtttcaat atattatagt ttgctctttg attttcattg
      301 agtattagtt caatatctaa aaaaagaacc ttgccaagca agattctttt agtgtctgac
      361 ttaaataatt gttcttctgg gaactaaatc gaattaagct tcgatttctg taaccatacc
      421 tgaaccaaca gtacgtccac cctcacggat agagaatgta gtaccttgtt ctacggcgat
      481 tgggtgaatc aactcaacgt cgattgtcac gttatcacca ggcattacca tttcagtacc
      541 tgctggaagt tcgattgaac ctgtaacgtc agtagtacgg aagtagaatt gtggacggta
      601 gttgttgaag aatggagtgt gacgtccacc ttcttcttta gtaaggatgt agacttcacc
      661 tttgaattta gtgtgtgggt tgattgaacc tggtttagcg ataacttgtc cacgttcgat
      721 ttcatcacgt tgaacaccac gaagaaggac acctacgtta tctccagcaa gaccttcgtc
      781 aagttgttta cggaacattt caacaccagt aacaactgct ttttgagttt cttctttgat
      841 accaacgatt tcgatttcgt cgttgacttt aacgatacca cggtcgatac gtcctgaagc
      901 aactgtacca cgtccagtga ttgagaatac gtcctcgact ggaagaagca atggtttgtc
      961 agtgtcacgt tctggttctg ggatatactc atcaactgtg ttcatcaatt ccataacgat
     1021 gtcttcgtat ttagagtcac cttcaagagc tttaagtgct gaaccttgga taactggaag
     1081 atcgtcacct gggaagtcgt attctgacaa taggtcacgg atttccattt caaccaattc
     1141 aagcaattct tcgtcgtcaa ccaagtcaac tttgttcatg aagacgataa ggtgtttaac
     1201 accaacctga cgtgaaagaa ggatgtgctc acgagtttgt ggcattggtc cgtcagttga
     1261 agctactaca aggatagctc cgtccatttg agcagcacca gtgatcatgt ttttaacgta
     1321 gtccgcgtgt cctggagcgt cgatgtgagc gtagtgacgt ttttcagttt cgtactcaac
     1381 gtgcgcagtg ttgatagtga taccgcgttc gcgttcttct ggagcagcat cgatagacgc
     1441 atagtcttta ggttggttaa ctgatgaagg caagcgacgt gccaaaacag ttgtgatagc
     1501 tgcagttagg gtagttttac cgtggtcaac gtgtccgata gtaccaatgt taacgtgtgg
     1561 tttactacga tcgtattttt cttttgccat ttgagtaaaa gcctccaata aaatatattt
     1621 tatagataga cagtaggcaa tacagtctaa ctttccttac tattttatca aatttcagct
     1681 aaattgcaag tgttttacaa cgtttttgtg aattattctt ggtaaaaatt taactaatta
     1741 atagaaagta ctaaatagac ttatccttca aggagttttc agcattatcc atccactcac
     1801 ttgctgaaaa tgtaaacagt ctctggttta tatagtaaaa tgaaacaaga atagggcaaa
     1861 tcgatcagga cagtcaaatc gatttctaac aatgttttag aagtagatgt gtactattct
     1921 agtttcaatc tactatacaa cctcaaaact gtgttttgaa caacctgcgg ctagcttctt
     1981 agtttgccct ttgattttca ttgagtataa aattgcagat aaaacgataa caatcatagg
     2041 actcagcaga gtcaatgtag gtcgaagaat agccccccta atcgcttatt ttatagcaaa
     2101 atgaaataga aactgaacat tttgttgagg aaggtaaatc aattcctcac aatgtttgag
     2161 aaagaaggga ggactattcc aacttcaacc cactataaag cagacttaca agatagggaa
     2221 cccatctccg ataatatata gtagaatgaa aactgcacaa tttgattgga gaattcaaac
     2281 caatttctaa caatgtttta gaaacaaggg tctattattt caactgcaac ctactatagc
     2341 ccattgaagc tggaatagcc cactgagact tctaaaccac tgctggagag gagtttgttt
     2401 agagtttctt tcatttccct aaaaaatcaa aaagagagaa ccagtctgat cctctcttac
     2461 ttatagatgg tgctcactca aatgttaaag gagctatttc ttagagataa aggaatttga
     2521 atacagctac tgccgcaatt gctgctgcga taggtgctac tactggtacc caagaatacc
     2581 accattttga atcgccttta tgctcaccaa gaactgattt tggaaggaaa gcatgaagga
     2641 gacgtggtcc caagtcacgg gctgggttca aggcaggtcc tgtaggtcct ccaagtgatg
     2701 ttaccaaagc cataacgagg aatccaagtg ccaagtgagc cacagaaagt cctgaagcag
     2761 tgtgtggagc cacctgtgct ttaatagcca agtcagaaaa atcaactgtt tgtcctgctt
     2821 ctattgcctt ttgtttcatg aattgaagca cttcagcacc aaagaagttt ttagtcaaac
     2881 caagagctgc aaagaacaaa acaaatgaac caacaaactc attaatcaaa ccattgacag
     2941 ttgctgcata gcgactttct tttgtaccat ggtcaatact tgaaatagtt gagaaagttc
     3001 ccaagatgtt atttgggttt tcagttttca agtagaatgg acggtatgtt gccacaacta
     3061 aggcttggcc aaagatagcc cccaagactt gcgcgataat gtaaggtacc acttgtgccc
     3121 aagggaaaag accgctaact gcaagcccta gagtgaaagc agggttgatg tgattcccag
     3181 atacgttacc aaacatcaag gctgggatca taacccccat accataacca acagcgatga
     3241 cgatccagcc actttggtga cctttcgtac ctttaagttc aacgttggca actgcaccat
     3301 tcccaagaat gatcaaaatg gcagttccca aaaattcagt ggcatacttc agtgcccatg
     3361 tgaaatccat ttgctagatt ctccttaaaa ttttttagat attccttatt ttatcaattt
     3421 ttaccctatt tagcaactga tttctggaaa tatttttaaa aaaataggat tcatagtttc
     3481 ccagttcaac ggacttgtaa gcgtttttat tcttcacgaa agacctcgtt ctcaaaacca
     3541 ggaaaaaagc ccacatctgt gagcttttcc ttgttcctag attctaaaat ctattatttt
     3601 tcatcttctt ttttcttgaa gaatcctaat cctagaccag ctaacaaggt catgatacca
     3661 gcactagcca aggtagcatt agcttctgta cctgtgtttg gcaattcctc tctcttacct
     3721 gtctcataag tcggaacttc tgggtctgga ttcactggag tttcagtttt tggagtacct
     3781 ggttctggag ttggtttatc tggtgttgat aaacggtcat accttaccgt tatttcttta
     3841 tcactagagt ctgacgtaac ttcttgtgat taaactgttg gaatatctgg agctttgtac
     3901 ttgtcaatct taccagatat aacctcgtcc cagtttcctg ttgtccattc accgtaggtt
     3961 acaactcccg tgaccttgtt ctcagttttt gtacggctta aggttacagg ttgaacaaca
     4021 tcttctttta cattttggtt cgtaacttta tcaacgtaat gaatgatacg cgttatagtc
     4081 ttcgtctcag tagaggttgc tgttttggga accactgttt cctcaacatt ctcacggtag
     4141 taatagtcaa ctgttgcacc gtcttctggt acgcatttgc aggagttgct accaaggtgt
     4201 atgttgtttt ccttgtgata actcggtctt ctttgtcctc agttgttgtt ttcccttcaa
     4261 tagtttttga ttctgtggta tactcagaac ctatcgctaa atcagctttt ataacagact
     4321 ctgccaactt ctcttggcta ccttctttat agtaattggc tgttactgta acagtggttg
     4381 gcgcttcgct ttctctataa actaaggtca ctgttctacc ttcgcttaca atattcccag
     4441 ttaaacttgc agaatttgta tctacttctt taaaagtata atattttccg tcagtagtag
     4501 tcatgctact gagtttttta tctgtgacat tgtagctggt accaatcagt tgttttttat
     4561 tggtaatgta ggttccgtca ctttcttttt ctccaattcc agtatcattt ttcaatgata
     4621 gcaaacgccc ttgttcatca acatagcgaa ctttcacatt ttctgagatt agttctgcca
     4681 attctgaagt ttttttcttt ttcttgattt cttcggttat tttccctttc tcttcttcgg
     4741 gaatatttag ttttggaatg attttttcaa caacggttcg tgatggttcc acagtatctt
     4801 ggatgactga aaagtcagct agaattggga gattatactg aacacggtga ctttgagtgt
     4861 ttactcctac tctttcatta ttctctgaaa atacttgtac ggtataagaa acaacatctt
     4921 ttcctaatag aacatcccca gtagagaaat agccgccttt tcctagtttg ctatctccag
     4981 agcccacttc tttcctaatc ttatcagata gttttttacc agtcagtaca ttcgttcgca
     5041 caatcccttt gtctacccct acaaagtggg agaacttttt gaactcttca gaaccagatc
     5101 tagcccaacc attattaagg gcatttgctt ttgtatttgt attctctctc aaaagtttgg
     5161 cgattagaat tatattcatc ggcacttaga gttgctgcta tatctgactc ttgaatacca
     5221 acttccttac taccatttct agcggcagta tatgtgtatt tatctgtttc tacttctagc
     5281 tgattatcct taacatgata ggtaattttc tcctggtata agagtcttca gtagtttata
     5341 tgctctgtca tcatctttag ctttagaagc agctgagttt agccaagttg gggtattagg
     5401 agtatcttta tcagcctgtt tcaagacatt attcaagtca tttgctagcc tattggttgt
     5461 cctcactgtg aaagttttct tccagtctga accactttta ttagacttag atatgctcat
     5521 gaaatcctgg tcaacattca acacaatatc gccttgtttt ttagcatctt ccgttgcttc
     5581 tgcttcaaat tgatcatgga gtttttgttg ctctggtgta tagttttttt atttacacga
     5641 tttaatgtac tattttttat tttagtatta agaactccat taatacgatt tttaaactct
     5701 gcttcaaaaa atcccttaat ttgttggtgc gcaagttcaa cattcaaacc ttttttatac
     5761 aagtcttcat tctgaacgat ttcggctaca cggtgaatgg tttgattgta taccgtcttc
     5821 tcttaaccag cagtatcctt agttttaatg actactcgat aggttccttt agaaccgtta
     5881 tagtcatcta gttttaaaaa agcattccaa acattcaaaa atagttggaa cttcccttaa
     5941 taaatccgtc actttctttt tcaagatagc ccaagcttgc tcaataggat tcaaatccgg
     6001 tgaataaggt ggtagaggta agaaaaagtg tttatcttgg atgcagagtt catccaaaat
     6061 gttcttggga tgaaaaccag cattgcccat gacaataaca tgaggtgtct tcaaagcagg
     6121 taggagttgc gttttgaacc actccacaaa gaaatcgctt gtcatgcttt tcttgtaaat
     6181 catgggagct ataaactctc cgtctacttg tcctgcaaca attgaagttc gctcaaaacg
     6241 acgtccgcta atcttttcat agactttctc ccctctagga gcccctgcat aaggacgata
     6301 gagatagcgg tcgattcctg tttcatcaat ataaacaggt gctaggtgct ttaaactatt
     6361 aaaattctta agaaataagg ctacttttct gggtcttgtt ccttaaagct cgtcatcttt
     6421 ttttaaagtg accttaatct gctttaaagc tgcccatact gaaggaacag cacaatcaaa
     6481 atgtgccgca atttcccgta aaaaagcatc tggatgagcc tctacaaagg ctttcaattc
     6541 ctctaaagga atctttcggt ttttgacgac tcgctttttc ctctctatgt gttcttgttc
     6601 acgtctttct tttcccacgt gaagagagtt ctgacgccaa caccaaaaaa cttggctgcc
     6661 tcgacatggc tgtgcccctc tttgatgtaa tctaatgctc gctgtttaaa atcagtacta
     6721 tatgccatag ctttattata atatgcttgt ttaaaactaa gtaactatat caatgttttg
     6781 ttatgagaag acttactttt tttactgaaa ttgaattttt cctagcctca acatcatata
     6841 accccaaaat tcaatctgac ctggtttgaa gagattttcg aagcagataa ggttttacta
     6901 aaactaaaaa aaatgatata atcaaactga ttaaatgttt taaaaataaa ggagaatttg
     6961 aatgtcttac caagaaaatt accagaaatg ggttgatttt gtggagcttc ctgactacct
     7021 tcgtcaagat ttggaaaata tggacgaaaa aactaaggaa gatgccttct atacaaatct
     7081 tgaatttggt actgcaggta tgcgtggctt ggttggtgct ggtacaaacc gtatcaacat
     7141 ctacgttgtt cgccaagcta ctgaaggatt ggctcgtttg attgagtcaa aaggtggaaa
     7201 cgagaaagaa cgcggtgtag caattgccta cgatagccgt cacttctcac ctgagtttgc
     7261 ctttgaatct gcggcagttc ttgctaaaca cggcatcaaa tcttacgtat ttgaaagcct
     7321 tcgtccaact ccagaactat catttgcagt tcgtcatctc aactgtttcg caggtatcat
     7381 ggtcacagcc agccacaacc ctgctccatt taacggttac aaggtttacg gtgaagacgg
     7441 tggacaaatg cctccacacg atgcggacgc tttgactact tatatccgtg caatcgaaaa
     7501 cccatttgca gttgaagttg ctgatgtgga aactgaaaaa gcttctggct tgattgaagt
     7561 tatcggcgaa gctgttgaca tagaatacct taaagaggtt aaggacataa acatcaaccc
     7621 agccttgatt gaagaatttg gtaaagacat gaagattgtc tacacaccac ttcatggtac
     7681 tggtgaaatg ttggctcgtc gtgctcttgc ccaagcagga tttgactctg ttcaagttgt
     7741 tgaagcgcaa gcaactgctg acccagactt ctcaactgta acatctccaa acccagaaag
     7801 ccaagcagcc tttgcccttg ctgaagaact tggtcgtcaa gttggtgcag atgttcttgt
     7861 cgcaactgac ccagacgctg accgtgttgg tgttgaagtt cttcaaaaag atggtagcta
     7921 cctcaacctt tcaggtaacc aaatcggtgc tatcatggct aaatacatct tggaagctca
     7981 caaaaacgct ggaactcttc ctgaaaatgc cgctctctgc aaatctatcg tttcaactga
     8041 cttggtaacg aagattgctg aaagctacgg cgcaactatg ttcaacgtct tgacaggttt
     8101 caaatttatc gctgaaaaaa tccaagaatt cgaagaaaaa cacaaccaca cttacatgat
     8161 gggatttgaa gaaagcttcg gttacttgat taaaccattt gtacgtgata aagatgccat
     8221 ccaagccgtt cttgtcgttg ctgaacttgc tgcctactac cgttctcgtg gtttgacact
     8281 tgctgacggt atcgaagaaa tctataaaga atatggctac tacgcagaaa aaacaatctc
     8341 tgttactctt tcaggtgtcg atggtgctga acaaatcaaa gcgattatgg ctaaattccg
     8401 caacaatgct ccaacagaat ggaacgcaac agctatcact gtcgtagaag acttcaaggc
     8461 acaaactgct actgttgctg acggtactgt tacaaacttg acaactcctc caagtgatgt
     8521 gttgaaatac acacttgctg acggttcatg gattgccgtt cgcccttcag gtacagaacc
     8581 aaaaatcaag ttctacattg cagttgtagg ggaaaccaac gaagaatcac aagctaagat
     8641 tgctaacatc gaagcagaaa tcaatgcatt tgtaaaataa agacctataa aagatggctt
     8701 tttgtcaact gtagtgggtt gaaaaaaagc taagcttgag aaaggacaaa tttcgtcctt
     8761 tcttttttga tattcag
//
LOCUS       DBERXF010000060         7980 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.60, whole genome shotgun sequence.
ACCESSION   DBERXF010000060 DBERXF010000000
VERSION     DBERXF010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7980
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.60"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(116..391)
                     /locus_tag="ACL8JK_001968"
     CDS             complement(116..391)
                     /locus_tag="ACL8JK_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGS1786782.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(498..1337)
                     /locus_tag="ACL8JK_001969"
     CDS             complement(498..1337)
                     /locus_tag="ACL8JK_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS1786783.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1479..2327
                     /locus_tag="ACL8JK_001970"
     CDS             1479..2327
                     /locus_tag="ACL8JK_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGS1786784.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2420..3337)
                     /locus_tag="ACL8JK_001971"
     CDS             complement(2420..3337)
                     /locus_tag="ACL8JK_001971"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HGS1786785.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3816..3964
                     /locus_tag="ACL8JK_001972"
                     /pseudo
     CDS             3816..3964
                     /locus_tag="ACL8JK_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
     gene            complement(4290..4583)
                     /gene="rpmA"
                     /locus_tag="ACL8JK_001973"
     CDS             complement(4290..4583)
                     /gene="rpmA"
                     /locus_tag="ACL8JK_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGS1786786.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4600..4944)
                     /locus_tag="ACL8JK_001974"
     CDS             complement(4600..4944)
                     /locus_tag="ACL8JK_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGS1786787.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(4960..5274)
                     /gene="rplU"
                     /locus_tag="ACL8JK_001975"
     CDS             complement(4960..5274)
                     /gene="rplU"
                     /locus_tag="ACL8JK_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGS1786788.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5310..5397)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5456..6160)
                     /locus_tag="ACL8JK_001976"
     CDS             complement(5456..6160)
                     /locus_tag="ACL8JK_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGS1786789.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     gene            6562..6861
                     /locus_tag="ACL8JK_001977"
     CDS             6562..6861
                     /locus_tag="ACL8JK_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGS1786790.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            7043..7980
                     /locus_tag="ACL8JK_001978"
                     /pseudo
     CDS             7043..7980
                     /locus_tag="ACL8JK_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2531 a         1629 c         1319 g         2501 t
ORIGIN      
        1 atacaatatt ttcggaacat tcaacttttt aactctattt attactagat ttcataatta
       61 aaaagcctac tgaccaagct agaaagcttg atacaatagg ctttttaaag actgattatt
      121 taacagcgtc tttaagagct ttaccagctt tgaatgctgg cactttagaa gctgcaattg
      181 tcatttcttt accagtttgt gggttgcgac ctttacgttc tgcgcgctca cgaacttcaa
      241 agttaccaaa accgatcaac tgaacttttt caccagctgc aagatagtca gctactgctg
      301 caaatacagc ttcaactgct gctgctgagt ctttcttagt caattctgta gcttctgcta
      361 ctttagcgat caaatcttgt ttgtttgcca tgttaatgat tcctccaaat aatttctaat
      421 taacaaatat aatcatatcc taaaatccct tttaggtcaa gttaaaaacg ctatttcttc
      481 ccattttatt tattttttta ggagtggtaa cgtatcaaaa tagcccaagc gttctcaccc
      541 gtgtgagttt gaataatgga acccgtttcc aaaacagaaa ttggcttttc aacataagct
      601 tgtaagcttt ctttcatctc ttttgcccaa tcatcactac cagaatatga aattccaatc
      661 tctgctacag cacgttcaga aagcgatgtt atcaactcat ctaaccattt tttaaatgtt
      721 ttagttccac gacctttaac cattggctgc aattcatggt ctttcatttg catgacaaca
      781 cggatattga gaagagagct caacaagcca gttacacggc taattcgtcc acctttgaca
      841 agattttcca aagttgaaac accaatataa agctctgtat ggtttttaac ctcttctaca
      901 tgagataaaa ttgcctccat atctttacct tcttgagcta acttcgcagc ctcaacaact
      961 tggaatttca gggcttggtc agtgaaggaa ctatcaacaa cagtcacatc tgcagtagat
     1021 aggctagcac cttggcgtgc tgcttctacc gtacccgaaa gagcatggga catatgaata
     1081 gcaagaatct ggccaccatc tttgcatagg tcttcaaaaa tctcagcaaa gacacctaca
     1141 ggtggctgac ttgttttcgg aagattctta ctttcttgca tcaactgaag aaatttacct
     1201 tcttctttca aatccgcatc agaataaaca acattatcaa tcattacaga taatggaaca
     1261 attgtaatat ctaattgctt tactagttca ggttcaatag taacagatga atcggttaca
     1321 atcttaattt ttgtcatagt atcaatcttt ctattttagg attcagattg gtttccttac
     1381 ttctaattat atcaaaaaaa agattaaaaa tcctaatgga gtcaatcaaa ttttccgtaa
     1441 aatttgatat aatcaactta taagaaaaga ggtgtcctat gattaaaaaa atttacccca
     1501 tttttaccat tttactaggt gctgctattt atgcttttgg actgacttat tttgtagttc
     1561 cccatcatct ctttgaagga ggggcgacag gcattaccct catcaccttt tatcttttta
     1621 aaatccctgt ttccctcatg aacctgctga ttaatattcc ccttttcatc ctagcttgga
     1681 agatctttgg agccaaatcc ctctattcta gtttactagg aaccttagct ttgtccgcct
     1741 ggttagcttt ttttgagcat attccccttc atattgatct tcaaggtgat ttactaatca
     1801 cagcccttat agcgggaatc ctattgggaa ttggccttgg aattattttt aatgctggag
     1861 gtacaactgg cggaactgat attctagctc gtattctcaa caaatacact catatatcca
     1921 taggaaaact gctctttatc ttagattttt gtattctcat gttgattctc ctaatcttca
     1981 aggatttgag attggtttcc tacacgcttt tgtttgattt tattgtttct cgtgttattg
     2041 atttgattgg tgaaggagga tatgccggca aaggctttat gattatcaca aaacgtcctg
     2101 accaacttgc taaggcgatt aatgatgacc tcggaagagg tgttactttt atttctggtc
     2161 aaggctacta tagtaaagaa aatttgaaaa tcatctactg tattgtcgga agaaatgaaa
     2221 ttgtgaaaac gaaggaaatg attcatcgaa tcgatcctca agcctttata actattacag
     2281 aagcccatga aatcctagga gaaggcttca cctttgaaaa agaataaaaa gaggtaatgt
     2341 cgtgacctca aaagttagac taaatcatct atcttttggg ttacagacaa cctctttttt
     2401 gttttattta ctcaagctct taagaccaat tccgagttac ttcttcatca gcctttaact
     2461 gatccactaa ttggtcaact gagtcaaatt tggtcatatc acgaatgcga tcaagccaat
     2521 aaaccatgac ggtttcccca taaatatctt gattaaaatc aaaaatattg acttcaaaac
     2581 gtgcttcttc tccatcaaag gtcacatttt tcccgacact agccatagca cgatacttct
     2641 gtctttgaat ctcaacatca acgacataaa cgccatctgc tggcatataa gtacggtcta
     2701 aaagcactaa attcgctgtc ggataaccaa ttgtacgacc acgagcatta ccatgaacca
     2761 ccatacctct tgatggaagc ggtgccccca aaagttttcc tgcttctttc acatttccat
     2821 ctaaaatagc ttgacggata cgagttgaac taatctttcc tttctcatct tctacaggtg
     2881 gaacaatgat aacttctcca tcaaagtaat cctttaaatc ttctgctgtt tttttgtcag
     2941 aaccaaatgt ataatcaaaa cctgcaacaa taattttggc attcatagcc ttgatataag
     3001 ttgcaaagaa ttcttgtgca gtgagactag cgaattgact actaaaatca aggagatata
     3061 attcttctac accttcgcgc tttaattttc tttcacgttc agcagggttc aaaatatgca
     3121 aaaacaaatc tggatgataa ggctctaaag cgatctttgg agattcatta aaggtcataa
     3181 cgacgatagg caataaatcc tttctcgcag ccttgttggc aacacgaaat aattcttgat
     3241 gccccttatg tatgccatca aaatagccga gaacaacgac tgaatcagat ggtgtgccaa
     3301 tatctttttg gttttttata ggaatagtaa taatcataaa ataattatat catagcgata
     3361 gctatttctg gaacagaaaa tctgaaatgt tgtttttttc acatgaagtg tacctgtttt
     3421 caaaaagcac tttattctat cgttgcttaa ctatgaactt tgcaatattc ttctcaaaaa
     3481 cttgtaggac atcttcaaaa ttttgcaagg agtgattaga cttgttcggt aaccataaag
     3541 tgtcatacta tgttatgtat gaaaaagcaa tgcaactaac tcctgagaac tttaaattac
     3601 taattggtgc cgaaaaggta gaatttagaa tcgaggtaca cctatggctg taaaatttac
     3661 aaaatgagac aacttgggca agatgtttga agaatttcct aaactccctg atttgaagca
     3721 agtcactttc cctgatgaca aagaaaaaag ccaaaacagc aaagaaaaac tagatgactg
     3781 ctttccaaca actcccatct agtgtgcttc agactgggct atttttctct ccatctgtta
     3841 gcttggattc tcagaccgtt tcagctaaag aatatctttt cccttatcag aaggaacggc
     3901 tcaaaccatt cagacaagtg aagggatgac aagccaatat ttgaaaccag atagcagttc
     3961 ttatagtcaa ttgaaataaa atctgaagaa atcgagtagg aaactcatat caatttttaa
     4021 cagtgttcta ttccagattc atactcaatg aaaattaaag tgcaaactag gaagttagcc
     4081 gcaggctgta cttgagtacg gcaaggtgaa attgacgtgg tttgaatttg attttcgaag
     4141 agtatcaatc cactatacat attaaaaagt atgggtatca aaataaaaaa acaggctctc
     4201 cgaaaactcg gaaagcctta ttttaagctg tttctagctt cctcaccttt acatttcaag
     4261 gttcgggata aaaggttcaa tgaacctttt tattttgcga ttgggtaaac agaaacttgt
     4321 tttttatcgc gtcctttacg ttcaaagcgt actacgcctt caactttagc gaacaaagta
     4381 tcgtctccac cacgaccaac gtttacacct ggatagatgt gtgtaccacg ttgacggtaa
     4441 aggattgatc cacctgttac agtttgtccg tcagctgctt tagctccaag acgttttgct
     4501 tgtgaatcac gtccgtttga tgtagaacct ccaccttttt tgtgggcgaa aagttgcaag
     4561 ttgttaagag tcatttttaa cataatgttt tcctccgtgt tagttttctg tgataactct
     4621 ggtttggacg aactcagaag agttctccga taagtttgcc atacctaaga aaaatgattc
     4681 aaagaataac tgggtcattt ctctctggtg tgaaggaaga tcttttggta tttcaaccat
     4741 cagatagcca ccttcatctt cgtttaattc taggattggt tcatagcctg caaatttctc
     4801 aatagaattg ataaagttaa tggcaagcgt agaaaccgat gcacacacga catctaagcc
     4861 gtattcgcca ctctcggcgt gtccagtaat ttccgcactc ctcagctcgc catcttcggc
     4921 tctctcaaag actgcctgta tcatgtgttc tccttaaaat taagcgttga ttgcgttgat
     4981 gacaactttt gtatatggtt gacggtgacc ttgtttacgg tggctacctt ttttaggttt
     5041 gtacttgtaa gtaaccactt tcttttgttt tccttgtttt tcaacagttc caactacagt
     5101 agctccagca acaagtggag ttccgacaac agtgttttca ccaccaacaa gaacaacttc
     5161 gttaaaagta acttcttgac cagcttcaac gttcaatttt tcaacgtaaa ctgcttgacc
     5221 aacttcaact ttaacttgtt ttccgccagt tttgataatt gcgtatgtgc tcattatgca
     5281 cctcctatga tttttatggg tttccccgat tttttgtgaa gactcgccta gcatcgtggg
     5341 acgaaccact taaacttgaa taatcaagca acgatgttcg tgcggttgca caggatcgtg
     5401 catagtcaac tcttcaagta tagcatatct cctattttct tacaagtaat aacacctaaa
     5461 atgaagcttt ttcttttact tttttctgcc aagaggcaaa aagcatgctg aggtaaaaaa
     5521 cgctcatcat aataggaaca ccaagaatgg tcttttcatg atagaaaatc gtcaaatagg
     5581 ctgaaaagac aacgccaagg acaaaactac taagcaggct aacaaatatg aatccttcac
     5641 gcaaaaaagg agtgtgcttg gttcggaaat aatctccaaa agccagcatg gtccgtttga
     5701 tattccctgt cataaaagcg ttattatagg caatacccga cacttctcca aaagcagttg
     5761 tcaccagtcc catacagaag gccaagggcg gcactagata gatattatcc acagtttgcg
     5821 gcacaaaagc aataatgatt gataagattg ccaagggaat caaggacaga ataggttttt
     5881 tcacaattct caatttttcc ttataaatcg ttaataaaaa gactcccatc ataaacgcta
     5941 gcaaggtgag aaccttgtcc ctaacatccg aaacattatt tttaattaat tctactgaaa
     6001 gaaagacaac atttccagtt tgtccagcta caagggtatt cccgcgaaca ataaaagtgt
     6061 aagcatccac atatccagca caaaacgtca aaaaaagtgc taacctttta gactgacgtg
     6121 atatttttct tataggtaat aacctcattt tacctcccat tgtattttct cttagaaata
     6181 ttgtaccatt ttctttctaa aaaatcgtag gctaccattt agattttact attagcataa
     6241 aaataataat agacaactat ttatccaaaa atagatagat gtaacatgtt tgcaaacaaa
     6301 gcatacgaac ctttagtaaa atcatttcca tgaaactaga atagagccct cttagcaaaa
     6361 atcattattt taatttattt ctaatcactc cttgacataa ataactctca ccaataaaag
     6421 actatgtctt aaaaaaatgg tataataaaa tcaatacttg ggcttgatgg ctatgctact
     6481 aataacaatt aggagagaaa atcaggcact tgttaacaac aaggattatc cccttgagat
     6541 gaaaggaact ttagaaatct tatgatgaac atgcaaaaca tgatgcgtca agcacaaaaa
     6601 cttcaaaaac aaatggaaca aagccaagct gaacttgctg ctatgcaatt tgttggcaaa
     6661 tctgctcaag atcttgtcca agcgacctta actggcgata agaaagttgt cagcattgat
     6721 ttcaatccag ctgtcgttga cccagaggac cttgagactc tttctgatat gaccgttcaa
     6781 gccatcaact ctgctcttga acaaatcgat gaaactacca agaaaaaact gggtgctttc
     6841 gctgggaaat tacctttcta aaaacaagga gctagaacaa tgcttgtcga taacaaaggc
     6901 taagaaaggt gcaaaaatga ctctataata tttgtagtgg gtaaatccac tatagatatt
     6961 atggagccta ttttattgta gaaaaaaagt cccatatgac ctataatgaa aagcgacaaa
     7021 acaactcatt agaaagaatc atatggaaca attacatttt atcacaaaat tactagacat
     7081 taaagaccct aatatccaga ttttagacat catcaagaag gatacacaca aggaaatcat
     7141 cgccaaactg gactacgacg ccccatcttg ccctgagtgc ggaaaccaat tgaagaaata
     7201 tgactttcaa aaaccttcta aaattcctta tcttgaaaca actggtatgc ctactagaat
     7261 tctccttaga aagcgtcgtt tcaagtgcta tcattgttct aaaatgatgg ttgctgaaac
     7321 ttctatcgtc aagaagaatc accaaatccc tcgtattatc aaccaaaaaa ttgcgcaaaa
     7381 gttaattgaa aagatttcta tgaccgatat tgcccatcag ctttccatct caacttcaac
     7441 tgttattcgt aagctcaatg attttcactt taaacatgat ttttcttgtc ttcctgagat
     7501 tatgtcttgg gatgagtatg cttttacaaa aggaaagatg agcttcattg cgcaagattt
     7561 taacaatctc aatatcatca ctgttcttaa gggaagaaca caagctgtca tccgaaatca
     7621 ctttcttaaa tatgatagag ccgtccgatg tcgcgtcaaa atcattacta tggatatgtt
     7681 tagtccttac tatgacttag ctagacagct tcgctttcaa atttctaggc tcaggctgaa
     7741 acagtctccc agactgtttc actcccgaat gctaaaatcg ttctagatcg tttccatatt
     7801 atccaacatc tcagccgtgc tatgagtcgt gtgcgtgtcc aaatcatgaa tcagtttcat
     7861 cgaaaatccc atgaatacaa ggctatcaag cgctactgga aactcattca acaggatagc
     7921 cgtaaactga gtgataagcg attttatcgt cctacttttc gcatgcattt aaccaataaa
//
LOCUS       DBERXF010000061         7732 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.61, whole genome shotgun sequence.
ACCESSION   DBERXF010000061 DBERXF010000000
VERSION     DBERXF010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7732
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.61"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..281
                     /locus_tag="ACL8JK_001979"
     CDS             <1..281
                     /locus_tag="ACL8JK_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1786791.1"
                     /translation="EFNRLSNVFSEEHIYYAHSYASWERGTNENHNRLIRRWLPKGTK
                     KMTPKEVAFIEKWINNYPKKYLDYKSPREDFWMANLNLKFSVRNKSRN"
     gene            277..951
                     /locus_tag="ACL8JK_001980"
     CDS             277..951
                     /locus_tag="ACL8JK_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HGS1786792.1"
                     /translation="MDSNFAGRLNILRAGVLDANDGIISIAGVVIGVASATTNIWIIF
                     LSGFAAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQN
                     GECKTSAQLLTNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPML
                     SVTIFPSEYRIPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLL
                     EQLFNI"
     gene            complement(993..2981)
                     /locus_tag="ACL8JK_001981"
     CDS             complement(993..2981)
                     /locus_tag="ACL8JK_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS1786793.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFVKNDGLKGQKTLTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(2983..3741)
                     /locus_tag="ACL8JK_001982"
     CDS             complement(2983..3741)
                     /locus_tag="ACL8JK_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1786794.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVMTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            4169..4360
                     /locus_tag="ACL8JK_001983"
     CDS             4169..4360
                     /locus_tag="ACL8JK_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786795.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(4714..4986)
                     /locus_tag="ACL8JK_001984"
     CDS             complement(4714..4986)
                     /locus_tag="ACL8JK_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGS1786796.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(5044..5493)
                     /locus_tag="ACL8JK_001985"
     CDS             complement(5044..5493)
                     /locus_tag="ACL8JK_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGS1786797.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTKRYRCGLCRGKLLLVNQPED"
     gene            complement(5480..7609)
                     /locus_tag="ACL8JK_001986"
     CDS             complement(5480..7609)
                     /locus_tag="ACL8JK_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGS1786798.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRAMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         2307 a         1624 c         1509 g         2292 t
ORIGIN      
        1 cggaattcaa tcgcttgtct aatgtatttt ctgaggagca catttattat gcacattcct
       61 atgcctcttg ggaaagggga actaatgaga atcacaacag gctcattcgt agatggttac
      121 ctaagggaac caagaaaatg actcccaaag aagtcgcatt catcgaaaag tggatcaaca
      181 actatcctaa aaaatacttg gactacaagt cacccagaga agacttctgg atggctaact
      241 tgaacttgaa atttagcgtc agaaacaaat cacgaaattg attcaaattt tgcaggtcgt
      301 ttaaatatcc tgcgtgcggg tgttcttgat gctaacgatg gaattatttc cattgctggt
      361 gtggttatcg gagttgccag tgccacgacc aatatctgga ttatcttttt atcaggtttt
      421 gcggctatct tagctggtgc cttttcaatg gctggtggag aatatgtatc cgtttcaact
      481 ccaaaagata ccgaggaagc tgccgtttcg cgagaaaaac tcttgttaga ccaagatagg
      541 gaactagcca aaaaatccct ctatgctgct tatatccaaa atggagaatg caaaacttct
      601 gcccaactct tgaccaataa gatctttctt aaaaatccac tcaaggctct ggtagaggaa
      661 aaatatggga ttgagtatga agaatttacc aatccttggc acgctgccat ttctagcttc
      721 gttgcctttt tccttagaag tttgcctcca atgctgtcag tgaccatatt cccaagtgaa
      781 tatcgcatcc ctgctactgt ccttattgtc ggtgtggccc ttcttctcac tggttacact
      841 agtgccagac ttggaaagga tccgactaga acagctatga ttcggaacct tgctattggt
      901 ctcttgacca tgggagttac cttcctgctc gaacaacttt tcaacattta gaatacaaga
      961 aatacctcga ttttgaagtc gaggtatctt ttttacattt gcacaatctt gcgataactt
     1021 cttgaagtaa tcatgaaaat cagcacatag gcgatgagga agatagcgca gatagacaag
     1081 gtcacaatca acatcatagt cgtatccagt acaccaatca cttttaaaat caggctaagc
     1141 atatggtagg caaaggcgag atgtatgaag gcaaagagca aaggaaggaa gaaaacagtt
     1201 aaaacctgtt tgttgatggt ttgcttgatt tgcttttggt ccaaaccgac tttctgcaag
     1261 ataataaagc gttcacggtc ttcgtagcct tcagaaattt gtttgtagta gatgaccaga
     1321 acagttccga ccataaagat aatggatagg aaaataccga taaagaagac accaccaaag
     1381 agggcactca tctgagaact agcatctgct agattgctac cataaacata gctaccttct
     1441 gtgtctaatt gagcattaaa ttgattgagg tagttttcat actcctcagc gaccttgagt
     1501 tgttcttctt cgctggcatc tacattcata ccaccgtaaa actgattata gatagccgaa
     1561 tctgggaatt gatccaaaaa ggcttgtaaa tcaggaacaa caaggtaatt gtaatcagta
     1621 gtcaagatat taaacttatt tggaacatgg ttgacaatga aatctttatt aaattcttct
     1681 ttgacagaaa attgatgatc atttagagtt agagttttct gtcctttcag tccgtcattt
     1741 ttgacaaaga gaccgacctc atttcctgat agagacagtt tttgaccagt catattttca
     1801 taatcttttt ggtcaaatac catgaaaact gtttttggtt ggacacggtt ttgtcctttt
     1861 tcaaaaatag ttaacttggt tccttcttga ttcgcaacag caaagtaagt gtaacgaagc
     1921 acttctttct ctttaatctt ataacctttg tcacttgcaa actggctcaa gagtttgtcc
     1981 aaatcttctt tttcaacatt ttgccctgaa accccaaaat catgaggatt tagaactttt
     2041 ttaaaggatt ctgcggaatt gaaaatgctt gtcgctgctg acatggttac caaaaccatt
     2101 gttgacaaaa tagcgatagt tgctagtcca actgcatttt tcttcatacg gaaaatcagg
     2161 ttggaaacag agatgaggtt attaggttgg taatagtatt tcttgttttt cttcaagatt
     2221 tgaagaaaaa cggtaatccc tgcattgaac aaaagataag taccaaagat aaccagtaaa
     2281 acagctatga agaaggttgt taaggctgta agaggatctt ttaccgtaag ggcaagataa
     2341 tatccaatcc ctaaacttat ggaaccaaga atagtttgga gaggaaggaa gcgacctttt
     2401 ttctctccgc tagctttctc acgtgagagc tggagggcat tcatacgggc gattcgaagg
     2461 gcattcagga acatgaggcc taggaaaatc aaaccgaaga caagaagtac tgtaatgaca
     2521 actttcatct ggaaggtagc gaccagttcc accttcaatt tcatcagttt gagtaggaaa
     2581 gcgaaaatca acttgtcaaa caaggctcca ataccgattc ctgctccaac agttagaatc
     2641 ccaaatagca ctaactcctt aaaggtcata ctgattagat ggcgcttctc caagcctaac
     2701 atgccatata tacccagttc cttggaacgg tttttcatga caaaactatt ggcatagagg
     2761 acgataatgg ctgacgcaag ggtaacgaca aacataccaa atccaagtgt tgcttgaatg
     2821 gtggttcctc cacggatttc cgcaatcttg ggattgaagg ttagggagta aaagagatag
     2881 gtgatggtga ctgccaagag aacagccagt gcaaagggat agtagagctt gcggttttta
     2941 atcaagttcg ataccgctaa cttattggtt aatcgaaaca tactaattca cctcgcttgc
     3001 catgacagtc aaggtatcag agatttcttg gaacatctga cgctctgtct tctctccacg
     3061 gtagatttgg ttgtaaagaa tgccgtcttt gataaagaga acacgcttgg ccctgctagc
     3121 agctgctgtt gagtgggtta ccatgaggat ggtttgccca cgctcattga tttcattaaa
     3181 gacatcaagt aaggctgcag atgacttgga atcaagggct cctgttggct cgtccgcaag
     3241 gagaatttca ggttctgtga tgatggcgcg ggctactgct acacgctgtt tctgaccacc
     3301 agaaatctcg taagggtact tctcttgcaa ttggttgata cccagatttt cagctgtcat
     3361 caccaatttc ttcatcatct ccgttatagg tcttcttgac aagacaagcg gaagcaagat
     3421 attgtcctta acagacagag tatctagcaa gttaaagtct tggaagacaa atcctagctt
     3481 ttcacgccgg aaactagaag cctgtgaatt tttaatagtt gctgtatcag ttccatttaa
     3541 gtaaacctga ccacgacttg gtttgtccag catagctagg atattgagaa gagtggattt
     3601 accagaacca gactcaccca tgatggcaac atagtcaccc ttttctacgg taaagtgaat
     3661 atccttgagg gcctctactt ggttgccctg aaaacgtgtt ttataaattt tttgaacgtg
     3721 ttttacatct aaaagtgtca tgagaatctc ctttcttaat atcccatcaa atgaaatgta
     3781 gcttgcatca tagtgcatcc cagctgaacg cgctcaattt ctttgtgact tggttttcta
     3841 gttttcttat gtaagatttg tttcatgatg ttactccttt gttctttatg agtctagttt
     3901 acatcaaaaa aagaccgctt gccataacct aaccttacaa aagagacttt aatcttacat
     3961 ttttgtaaga ttgggtgaaa tataagcaaa attacttaga aaatgatttg atttcctatt
     4021 tttaaagttg taaaatataa gtgtgaaaag gcttactttg aaaaggagga agcgggaact
     4081 aacattttag taaggttacc tagataacat accattcaat ttaacacttg caagtcgttc
     4141 aacctataag gaaagaaggt gcgctttaat gaaacacaaa gaacatatac tcatcggact
     4201 tctctatctg ctctctccat tcatcggtca gctcttagtt gaacacacac actttatcag
     4261 tacagaattt accggcactg cttatgttat ttgctggtta tcagttgtta tcagcatcca
     4321 ccatttttcc aaaaatgtat tgtctcaaca gcaaaaatag attaaaaaac tgcgtttaaa
     4381 ttactgcttt tatagtaaaa tgaaataaga acaggacaaa tcgatcagga cagtcaaatc
     4441 gatttctaac aattttttag aagtataggt gtcctattct agttccaatc cactatagtt
     4501 tgtggatgaa gctggcgaaa tattattaat actattcaaa aatcaaagtg caaactatat
     4561 caacttcaca ttgccgacta aattacagcc tgcggctggc ttcctagttt gcactttgat
     4621 ttttattgag tataaaagta aaaaagcttt aaatcaagca gtttagacta ttgatttaaa
     4681 gctttttgcg tattccaaat cttttgtaaa acctcaccaa aaccagcctt cattatcgtc
     4741 aatggcttga gcttctttgc gtttacgtgg gcctgttccg tacatttctg cttcgatttc
     4801 ttccttggtt ggcatgatag aagctaggat gatatagata atcaccccaa gtccaaagtt
     4861 tgcgactgta aaaatggcaa acagaaaacg tacaagggta acatcaaagt tccacttgtc
     4921 tgacagacct gctaaaactc ctgaaatcat gcgatttcgt ctcattttat aaaacttact
     4981 gttcatgata tttcctcttt ctgctaggtt agactagtat atcacggata ggctcggctt
     5041 tcatcagtcc tcaggctgat ttactaatag caactttcct cgacaaagtc cacagcgata
     5101 gcgtttggta tcaatcctac gcttacgctg ataagtttgc tggcaggatt ggcaacgata
     5161 gagcttgatt ggcttggagt tactattggg caaggatggt acaaaccgta atccatccac
     5221 tgctttcaac agttccttaa aatcccgatc cttgtgttga tagcctttcc cttgaaaata
     5281 gaggtgataa tgacagagtt catgtcggac aattttccta aaaacgtcca accccagttc
     5341 ctgataaacc ttgggattaa aatccaaatg cccatctttg gggaaaaatc gcccacctgt
     5401 cgaacgtaga cgcctattcc actggacatg atggataaaa ggtctgccga agtcttctag
     5461 tgaaacctgc ttgacgtaat cagtcagttt catttggagc taggagagac agattaactt
     5521 tttcacgttc agtatcaatt ttcttaaccc aaacgctcac caaatctcca actgccacca
     5581 cttgactagg gtgtttgata aacttgcgac tcatatggga aatatggatg agaccgtcct
     5641 catgaattcc gatatcaaca aaagcaccga aatcaacaac gttacgcacc actccttcta
     5701 gcttttgtcc aaccactaag tccttgatat ctaggacatc ttgacggaga actggagcat
     5761 caaaggaatc acggaaatct cgacctggtt tgagaagatc tgcaatgata tctttaagag
     5821 tttctggacc aaggtctaac tcttgcgcca tttccttgac tgaaagcgac ttgagtttgc
     5881 tttgggcctc ttcattcaga tccttaatgt ccaagcattt gaagagttcc ttaacggcag
     5941 cgtaattttc tgggtgaact cctgtattat caaggatatt gctactttca gggatacgga
     6001 ggaaaccagc agcctgttca aaagccttgg cccccaaacg aggaactttc ttgatttggg
     6061 agcgtgaagt gatttttccc tcttcctcac ggtatttgac gatattttca gaaatggttt
     6121 tattgagtcc agctacgtgt gaaagaagag ctgggctagc tgtattgaca ttgacaccaa
     6181 cttggttaac cactgtatcg acaacaaagt ccagactctc agatagtttc ttctgactga
     6241 catcgtgttg gtattgaccg acaccaattg acttaggatc gattttgacc aattccgcaa
     6301 gaggatcttg caaacgacgg gcgatagaaa tggcagagcg tttttcaacg gtcaagtctg
     6361 gaaactcctg acgagcaagt tcgctggcag aatagacaga agcaccactt tcattaacga
     6421 taacatagct gacttcaggg aaatctttca gaacttccgc tacaaaagct tcactttcac
     6481 gactggccgt tccatttcca atggcaataa tctctacacc gtattgacca attaaatctg
     6541 ctaaatcttt cttggcttct tcgatttgac gagctgatgc tggtttaaca ggataaataa
     6601 cctgagttgt cagcattttt cctgttgcat ccacgacagc tagcttggca cctgtacgaa
     6661 aggctgggtc aaacccaaga accacgcgcc ctttcagtgg agcaaccaag aggagattgc
     6721 gcagattgtc agaaaaaagt tggatagctc cctcttcagc tttctcagtt aattctgtcc
     6781 gaatacgacg ctcaatagca ggcaagacct ttttcttaac ggattgctga acaacttcat
     6841 caatataagc atttttcacc ttgaaacgag tagcaaagaa ggcaagaata cggtccgtcg
     6901 catgttcaaa accgatcttc aagacaccaa gtttctcccc acgattgaga gccaaggtac
     6961 gatagccttg catagttcca actgtctctg aaaaatcata ataaatctga aaaacctgct
     7021 tttcatcaag actttcatcc ttggcttgag aagtgagttt agagtgtctc agcacttcct
     7081 gataagtcat agcacgcaat gtcacatctt ccgataaggc ttcgaccaaa atatcaactg
     7141 caccggtcaa ggcttccttg ccagtcgcaa atccttcaca gacgaacttt tcagcttctt
     7201 tctctaagtc aactatattc tgcaaaatca agcgagcaag aggaaagagt ccagcttcac
     7261 gggcaatggt tgccttggta cgacgctttt ccttataagg aagatagagt tcttcaacgt
     7321 ctgctaattt ttcggcaact aagatagctt cttccaattc cttggtcaac ttaccttgtt
     7381 cttgaatctt agctaagaca gcttccttac ggtcattgag atttgtcaga cttttatcca
     7441 aatcaataat agccttaatc gccacctcat ccagactacc agtcatgtcc ttgcgataac
     7501 gcgcgataaa gggaatagtc gccccttcag ctgtcaaact tagaacggta tcaatttgct
     7561 ttaacgtcac tcccaaatcc tgagagattt tttcatattt tttatccata aatctattat
     7621 accacaagct ggaaggcttt ctccaatcct tttcatactc aatgaaaatc aaaaagcaaa
     7681 ctaggaagct agccgcaggc tgctcaaaat actgttttga ggttgtggat aa
//
LOCUS       DBERXF010000062         7145 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.62, whole genome shotgun sequence.
ACCESSION   DBERXF010000062 DBERXF010000000
VERSION     DBERXF010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7145
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.62"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..259
                     /locus_tag="ACL8JK_001987"
     CDS             <1..259
                     /locus_tag="ACL8JK_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1786799.1"
                     /translation="WFQKFFLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLP
                     PYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEAFLSCSCFN"
     gene            320..1282
                     /locus_tag="ACL8JK_001988"
     CDS             320..1282
                     /locus_tag="ACL8JK_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGS1786800.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPIESLCYE"
     gene            1459..2466
                     /gene="gap"
                     /locus_tag="ACL8JK_001989"
     CDS             1459..2466
                     /gene="gap"
                     /locus_tag="ACL8JK_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGS1786801.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2534..3409)
                     /locus_tag="ACL8JK_001990"
     CDS             complement(2534..3409)
                     /locus_tag="ACL8JK_001990"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS1786802.1"
                     /translation="MQFTFTLPASLPQMTVKQLLEEQLLIPRKIRHFLRIKKHILINQ
                     EEVHWNEIVNPGDVCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTH
                     GNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISR
                     EYWALVDGNINKKELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLA
                     HCKLKTGRTHQIRVHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTF
                     TTLSNTFEKELKKNG"
     gene            3496..5691
                     /gene="pbp2a"
                     /locus_tag="ACL8JK_001991"
     CDS             3496..5691
                     /gene="pbp2a"
                     /locus_tag="ACL8JK_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HGS1786803.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTSAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYTVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5744..5896
                     /gene="rpmG"
                     /locus_tag="ACL8JK_001992"
     CDS             5744..5896
                     /gene="rpmG"
                     /locus_tag="ACL8JK_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS1786804.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5906..6082
                     /gene="secE"
                     /locus_tag="ACL8JK_001993"
     CDS             5906..6082
                     /gene="secE"
                     /locus_tag="ACL8JK_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGS1786805.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6137..6673
                     /gene="nusG"
                     /locus_tag="ACL8JK_001994"
     CDS             6137..6673
                     /gene="nusG"
                     /locus_tag="ACL8JK_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGS1786806.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            6795..>7145
                     /locus_tag="ACL8JK_001995"
     CDS             6795..>7145
                     /locus_tag="ACL8JK_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGS1786807.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRKYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYR"
BASE COUNT         2242 a         1230 c         1550 g         2123 t
ORIGIN      
        1 atggtttcag aagtttttct taccaacatt aaccacacca tcggttatta ttatggataa
       61 tgcaagattc catagaatgg ggaagctaga actcttgtgt gaagagtttg ggcataaact
      121 tttacctctt cctccctact cacctgagta caatcctatt gagaaaacat gggctcatat
      181 caaaaagcac ctcaaaaagg tattaccaag ttgcaatacc ttttacgagg cttttttatc
      241 ctgctcttgt ttcaattgac tatatatcac ggatacagtt gggaaagaag ctattaaata
      301 tttggagagt ccttttggga tgaacatgtc aaatattact atagatgggc aagaaatgga
      361 tctgagtcaa acgatgcctt cttatgctca agtagtgagt ctttatgatg atacaagtat
      421 ctctgttagt aataatgaga cggacaaagt gttggctgga tccctctata ctgatacaaa
      481 tgaacaggga ttaacgattc caagcagttt actaaaaaat tggaatgaac agacaggaaa
      541 aaatttgaca gctaatgatc ttattggcaa atcagtctca gccagcattg tagaaagtgc
      601 tgccgaaact agtaagattg ctcaatttca aacgaagatt gtacgtgtaa tcaatgatga
      661 agatgacatg gaggacagca acagtttcat gctgtctcat caaatggaaa cgattttgaa
      721 agaggctgga tttacgaaag ctgtatctta ttttatcttg gaactcaaag atccatcaca
      781 gacaaaagta gtaacagaag aattacagaa aaataagaag tatactgtgc tttctcaaca
      841 gagagttctt gatattgtga ttacctttat tcgtgttatt cagggattat tgattgtgct
      901 ttcatcacaa gctattgtgg tagcagcggt tatgattggt atcattattt acatcaatat
      961 catgcaacgt tccaaggaaa taggtgtcat gaaagcagtt ggttatcaga atcgtgatgt
     1021 caaaggaatt tttatttacg aggctatctg gattgtaggc atcgccttgc tgctggcatt
     1081 tttggttgca caaggggtgg gaagtttggc gaatgcgatt gtaagtcact tttacccatc
     1141 catcactaag gtttttgaat taaatctttt atctgtttta ggaactctag ttttcgctct
     1201 attacttggt tatgtctcag cctacttccc ggcgcgtaag attagtaaaa tggatcctat
     1261 agaatcgtta tgctatgaat agtaagggat tccttggttt acagtcttaa aaagaaacta
     1321 acatagaaaa acaatggcca tacttgcaat tcaactcaaa tagttgtata ataggtttgt
     1381 tgaaaggtga tttgtagtga ttcaagttac tcttttcaca ataaaaattt catgattttc
     1441 ataaggagga aatcactaat ggtagttaaa gttggtatta acggtttcgg acgtatcggt
     1501 cgtcttgctt tccgtcgtat ccaaaacgta gaaggtgttg aagttacacg catcaacgac
     1561 cttacagatc cagttatgct tgcacacttg ttgaaatacg acacaactca aggtcgtttc
     1621 gacggtactg ttgaagttaa agaaggtgga tttgaagtta acggtaaatt catcaaagtt
     1681 tctgctgaac gtgatccaga acaaatcgac tgggctactg acggtgtaga aatcgttctt
     1741 gaagctactg gtttctttgc taagaaagaa gcagctgaaa aacaccttaa aggtggagct
     1801 aaaaaagttg ttatcactgc tcctggtgga aacgacgtta aaacagttgt attcaacact
     1861 aaccacgacg ttcttgacgg tactgaaaca gttatctcag gtgcttcatg tactacaaac
     1921 tgcttggctc caatggctaa agctcttcaa gacaactttg gtgttgttga aggattgatg
     1981 actactatcc acgcttacac tggtgaccaa atgatccttg acggaccaca ccgtggtggt
     2041 gaccttcgcc gtgctcgcgc tggtgctgca aacatcgttc ctaactcaac tggtgctgca
     2101 aaagctatcg gtcttgtaat cccagaattg aatggtaaac ttgatggatc tgcacaacgc
     2161 gttccaactc caactggatc agttactgaa ttggtagcag ttcttgaaaa gaacgttact
     2221 gttgatgaag tgaacgcagc tatgaaagca gcttcaaacg aatcatacgg ttacacagaa
     2281 gatccaatcg tatcttcaga tatcgtaggt atgtcttacg gttcattgtt tgacgcaact
     2341 caaactaaag ttcttgacgt tgacggtaaa caattggtta aagttgtatc atggtacgac
     2401 aacgaaatgt catacactgc acaacttgtt cgtactcttg aatacttcgc aaagattgct
     2461 aaataattct tgagttgata gaaagcaagg ctttgtggtc ttgctttttt atatggaaaa
     2521 atggatgaca cgatcatcca ttctttttta attctttttc aaatgtattt gaaagggtag
     2581 tgaaagttag cctctctaaa gtaagtgggt gggtaaagga aagtcggaag gcatgaagca
     2641 taagccggct tgtctttgat ttactattat agagagggtc tcccaggata ggaagattat
     2701 gatgcaaaag gtgcacacga atctgatggg ttcgccctgt ctttagcttg caatgagcca
     2761 aggaagtctt gtttgagaat tgctttaatc tgcttacatg cgtttcagca tattgcccat
     2821 tttttgcatc aactattctt tttctacgat catggcgatc acgtccaatt ttgtctctga
     2881 aaacaagttc ttttttgttg atatttccat caactagagc ccaatattct ctagaaatct
     2941 cttttttctc caataagcga ttgagaatgg gcaggataaa aggatttttg gcaaagagaa
     3001 ctaagccact ggtttccatg tccagacgat gaacgacata gcaggtttgg ccaacatagg
     3061 tactaacatg gttaagaagg gcaatttcgt ttggttgatt accatgcgtt ttcataccct
     3121 ctggtttgtt tacaataatc aagtgttgat cttgataaac ttcctgcact aagtctgggt
     3181 tgccccaagg gatcgtcttt tggggataat cttcctcgtc aaaagtcaac tggcaaacat
     3241 ctccaggatt tacgatttcg ttccagtgga cttcttcttg atttatcaaa atatgtttct
     3301 tgattctcaa aaaatgacgg atttttctag ggatgaggag ttgttcctca agtaattgct
     3361 ttaccgtcat ttgaggtaga gaggcgggta atgtaaatgt gaattgcata cagatattgt
     3421 aacaaaaaaa gccctatttg gataggaaat agctaaattc ttgtcttcct atgatgaaga
     3481 tgataaaata aacgcatgaa attagataaa ttatttgaga aatttctttc tctttttaaa
     3541 aaagaaacaa gtgaactaga ggactctgat tctactatct tacgtcgctc tcgtagtgat
     3601 cgaaaaaaat tagcccaagt aggtccgatt cgaaaattct ggcgtcgtta tcatctaaca
     3661 aagattatcc ttatactagg tttgagtgca ggcttgctag ttggaatcta tttgtttgct
     3721 gtagccaagt cgaccaatgt caatgatttg caaaatgcct tgaaaactcg gactcttatt
     3781 tttgatcgtg aagaaaaaga ggctggtgcc ttgtctggtc aaaagggaac ctatgttgag
     3841 ctgactgata tcagtaaaaa cttgcagaat gctgttattg cgacagaaga ccgttctttc
     3901 tataaaaatg acgggattaa ctatggccgt ttcttcttgg ctattgtcac tgctggacgt
     3961 tcaggtggtg gctctaccat tacccaacag ctggctaaaa acgcctattt atcacaagat
     4021 caaactgttg agagaaaagc gaaagaattt ttccttgcct tagaattaag caaaaaatat
     4081 agtaaggagc aaattctaac catgtacctt aacaacgctt attttggaaa tggtgtgtgg
     4141 ggtgtagaag atgcgagtaa gaaatacttt ggagtttctg catcagaagt gagtctggat
     4201 caagctgcga ctctggcagg gatgctcaag gggccggaac tgtataatcc cttgaattcc
     4261 gtagaagatt ctactaatcg gcgcgatact gtcttgcaga atatggttgc agcaggatat
     4321 attgataaaa accaagaaac cgaagctgct gaagttgata tgacttcgca attgcacgat
     4381 aagtatgaag gaaaaatctc agattaccgt tacccctctt attttgatgc ggtggttaat
     4441 gaagctgttt ccaagtataa tctaacagag gaagagattg tcaataatgg ctaccgcatt
     4501 tacacagagc tggaccaaaa ctaccaagca aatatgcaga ttgtttatga aaacacatcg
     4561 ctatttccga gggcagagga tggaacgtct gctcaatcag gaagtgtagc tctcgaaccg
     4621 aaaacagggg gagttcgtgg agttgtcggt caagttgctg acaatgataa aactggattc
     4681 cggaatttca actatgcaac ccaatcaaag cgtagtcctg gttctacaat taagccttta
     4741 gttgtttata cgccagcagt tgaagcaggc tgggctttga ataagcagtt ggataaccat
     4801 accatgcagt atgacagcta tacggttgat aactatgcag ggatcaaaac gagtcgagaa
     4861 gttcctatgt atcaagcctt ggcagaatcg cttaatctac ctgctgttgc cactgttaat
     4921 gatttgggtg tcgacaaggc ttttgaggca ggcgaaaaat tcggactcaa catggaaaag
     4981 gtcgaccgtg ttcttggtgt cgccttggga agcggtgttg aaaccaaccc tcttcaaatg
     5041 gctcaagcat acgctgcctt tgcaaatgaa ggtttaatgc ctgaagctca ttttattagt
     5101 agaattgaaa atgctagtgg acaagttatt gcgaatcata aaaattcaca aaaacgggtg
     5161 attgataagt ctgtagctga caagatgacc agtatgatgt tggggacttt caccaacggt
     5221 accggtatta gttcatcgcc tgcagactat gtcatggcag ggaaaactgg aacaactgaa
     5281 gcagttttca atccggagta cacaagtgac cagtgggtaa ttggttatac tccggatgta
     5341 gtgattagcc actggcttgg ctttccgacc actgatgaaa atcactatct agctggctct
     5401 acttcaaacg gtgcagctca tgtctttaga aacattgcca ataccatttt accttatacg
     5461 ccaggaagta cctttacggt tgaaaatgct tataagcaaa atggaattgc accagccaat
     5521 acaaaaagac aagtacaaac caatgataat agccagacag atgataattt gtctgatatt
     5581 cgagggcgtg cgcaaagtct agtagatgag gctagccggg ctatctcaga tgcgaagatt
     5641 aaggaaaagg ctcaaacaat atgggattcg atagtcaatc tatttcgcta agatgcttgt
     5701 caaagcctag ctttcttgtt ataatggata agatggaggc gttatggcac taaaaaaagc
     5761 aagcctagct tgtgcggttt gtggttcgag aaactattca atcaagatca gcggaaaccc
     5821 caagcctaca cgactagaag taaataaatt ttgtaagcat tgtggcaagt acactacaca
     5881 cagagaaacg agataggaga gagcgatgcg ttttattgga gatattttta gacttcttaa
     5941 agacacaaca tggccaactc gcaaggaaag ctggagagat tttcgttcta tcatggaata
     6001 cacagctttc tttgtagtaa ttatttacat ttttgaccag ttgattgttt caggtttgat
     6061 tcgatttatt aacatttttt agaagattag tggagttaat tacactagaa atcttctatt
     6121 tatgaaagga aatatcatgg atagttttga taaaggatgg tttgttttac aaacttattc
     6181 tggttatgaa aataaggtga aagaaaatct attacaacgt gcacaaacct acaatatgtt
     6241 ggataatatt ctacgcgttg aaattccaac acaaacagtg caagttgaaa aaaatggaaa
     6301 gagaaaagaa gtagaagaaa atcgctttcc aggttatgtt cttgtagaaa tggtcatgac
     6361 agatgaagct tggtttgttg ttcgaaacac accaaatgtt acaggatttg tcggatcaca
     6421 cgggaacaga tcaaaaccaa ctccattatt ggaacaagaa attcgtgaca ttttggtatc
     6481 tatgggacaa actgttcaag aatttgattt cgatgttgag attggtcaaa ctgtacgtat
     6541 tattgatggt gcttttgcag actacactgg taagattaca gaaattgata ataacaaagt
     6601 gaaaatgatt atctctatgt ttggtaatga cacagttgca gaagtaaacc taaaccaaat
     6661 cgcagaatta taatcctgag agaggctgga gcctctcttt tttgtgcagt ttaggagcta
     6721 aagggaacag aatggagaaa atggaacaaa tgtgttttct aatctgttag actgtatcta
     6781 gaaaggggaa aattatgatt aaagaattgt atgaagaagt ccaagggact gtgtataagt
     6841 gtagaaatga atattacctt catttatggg aattatcgga ttgggaccaa gaaggcatgc
     6901 tctgcttaca tgaattgatt agtagagaag aaggactggt agacgatatt ccacgtttaa
     6961 ggaaatattt caaaaccaag tttcgaaatc gaattttaga ctatatccgt aagcaggaaa
     7021 gtcagaagcg taaatacgat aaagaaccct atgaagaagt gggtgagatc agtcatcgta
     7081 taagtgaggg gggtctctgg ctagatgatt attatctctt tcatgaaaca ctaagagatt
     7141 ataga
//
LOCUS       DBERXF010000063         6760 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.63, whole genome shotgun sequence.
ACCESSION   DBERXF010000063 DBERXF010000000
VERSION     DBERXF010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6760
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.63"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..339)
                     /locus_tag="ACL8JK_001996"
                     /pseudo
     CDS             complement(1..339)
                     /locus_tag="ACL8JK_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            537..2303
                     /gene="patB"
                     /locus_tag="ACL8JK_001997"
     CDS             537..2303
                     /gene="patB"
                     /locus_tag="ACL8JK_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HGS1786808.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMIDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            2442..3131
                     /locus_tag="ACL8JK_001998"
     CDS             2442..3131
                     /locus_tag="ACL8JK_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGS1786809.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            3135..3314
                     /locus_tag="ACL8JK_001999"
     CDS             3135..3314
                     /locus_tag="ACL8JK_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786810.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNYDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            3301..4650
                     /locus_tag="ACL8JK_002000"
     CDS             3301..4650
                     /locus_tag="ACL8JK_002000"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGS1786811.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            4774..6234
                     /gene="gltX"
                     /locus_tag="ACL8JK_002001"
     CDS             4774..6234
                     /gene="gltX"
                     /locus_tag="ACL8JK_002001"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGS1786812.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGEHSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            6248..6682
                     /locus_tag="ACL8JK_002002"
     CDS             6248..6682
                     /locus_tag="ACL8JK_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGS1786813.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         2127 a         1295 c         1456 g         1882 t
ORIGIN      
        1 ttctaactta gtcttaagat aggccttaaa agcaggtgaa aagcgagggc atgctttggc
       61 agcttgtatg agtgcctacc gcagatgagg ggaaccccgt ttgatcattc ttccagctaa
      121 atcaatctga tctgactgat aaatagaaga atccagtcca gcgaaagctt gtaattgagc
      181 aagattatca aaggcatgaa tatttcgaat ctcggctaaa atgaccgccc ctaaacgatt
      241 cccaatccca gtaaccgtcg tgatgatcga gttgaactca gccatcaagt cattgacaca
      301 tgtttccgcc ttgtcaatga gcctcttgta atgtttgatg ttttcattac acgagataaa
      361 acgtttatgc gttatcaaac tcatgaccaa ttgaaacaaa aagctgtggt tagatccttt
      421 cggaaattgt caagcgattg gaggaaatga actaatccac agcggcttat tccaagtata
      481 ccacttgggc tttggcagta gctaactgcg ctaaatataa tataaggagg agtaaaatga
      541 agacagttca atttttttgg cattatttta aggtctacaa gttctcattt gtagttgtca
      601 tcctgatgat tgttctggcg acttttgccc aagccctctt tccagtcttt tctggacaag
      661 cggtgacgca gctagccaat ttagttcaag cttatcaaaa tggcaatcca gaacttgtat
      721 ggcaaagcct atcaggaatc atggtcaatc ttggcctgct ggttttggtt ctatttatct
      781 ctagtgtaat atacatgtgt ctcatgacgc gcgtgattgc agaatcgacc aacgagatgc
      841 gcaaaggcct ctttggtaag cttgctcagt tgacggtttc tttctttgac cgtcgacaag
      901 atggcgatat cctgtctcat tttaccagtg atttggataa tatcctccaa gcctttaacg
      961 aaagcttgat tcaggtcatg agcaatattg ttttatacat tggtctgatt cttgtcatgt
     1021 tttcgagaaa tgtgacgctg gctctcatca ccattgccag caccccattg gctttcctta
     1081 tgctgatttt catcgtgaaa atggcacgca aatacaccaa cctccagcag aaagaggtag
     1141 ggaagctcaa cgcctatatg gatgagagca tctcaggcca aaaagccgtg attgtgcaag
     1201 gaattcaaga ggatatgatg gcaggatttc ttgaacaaaa tgagcgcgtg cgcaaggcaa
     1261 cctttaaagg aagaatgttc tcaggaattc ttttccctgt catgaatggg atgagcctga
     1321 ttaatacagc catcgtcatc tttgctggtt cggctgtact tttgaatgat aagtctattg
     1381 aaacaagtac agccctaggt ttgattgtta tgtttgcaca attttcacag cagtactacc
     1441 agcctattat ccaagttgca gcgagttggg gaagccttca gttggccttt actggagctg
     1501 aacgaattca ggaaatgttt gatgcagagg aggaaatccg acctgaaaag gctccaacct
     1561 tcactaagtt gcaagaaagt gttgaaatca gtcatatcga tttttcatac ttgcctgata
     1621 aacctatttt gaaagatgtc agcatttctg cccctaaagg ccagatgaca gcagttgttg
     1681 ggccgacagg ttcaggaaaa acgactatta tgaacctcat caatcgcttt tatgatgttg
     1741 atgctggtgg tatttatttt gatggtaaag acattcgtgg ctatgactta gatagtctta
     1801 gaagcaaggt gggaattgta ttgcaagatt cggtcttgtt tagcggaacg attagagaca
     1861 atatccgatt tggtgtgcca gatgctagtc aggaaatggt tgaggtagca gcaaaagcaa
     1921 cccacattca cgactatatc gaaagtttgc ctgataagta cgatactctt attgatgatg
     1981 accagagcat cttttcaaca gggcagaagc aattgatttc aatcgctcga accctgatga
     2041 tagatccaga agttctcatt ctcgatgaag caacttcaaa cgtagatacg gtgacagaaa
     2101 gcaagattca gcatgccatg gaggtggttg tagcaggtag aactagtttc gtcattgccc
     2161 accgcttgaa aaccattctc aatgcagatc agattattgt ccttaaagat ggagaagtca
     2221 ttgaacgtgg taaccaccat gaacttttga agctaggtgg cttttattca gaactctatc
     2281 acaatcaatt tgttttcgaa taagaaagaa gttgtcctat gtgggcagct ttttcttgtc
     2341 cataaaaaat gtttatcaca gccttaaaaa aaacatatta gacgaaagtc attttgagtg
     2401 atatgatagg actatcgtta gcattcgaaa ggagaggcat catggctaga acggttgtag
     2461 gagttgctgc aaatctatgt cccgtagacg cagaaggcaa aatcattcat tcatctgtat
     2521 cttgtagatt cgcagagatc attcgtcaag tcggtggtct ccctttagtc attcctgttg
     2581 gtgatgagtc agttgtacgt gattatgtgg aaatgattga caaactcatt ttgacaggag
     2641 gccaaaatgt tcatcctcag ttttatggag agaaaaagac cgtcgagagc gatgattaca
     2701 atctggtccg tgacgaattt gaattggcac tcttgaagga agcgcttcgt cagaataaac
     2761 caattatggc aatctgtcgc ggtgtccaac ttgtcaatgt tgcctttggt ggaaccctca
     2821 atcaagaaat cgaaggtcac tggcaaggac tacctttcgg gacatctcac tctattgaga
     2881 cagtagaagg aagcgtggtg gctaagctat ttgggaaaga aagtcaggtc aactcagtcc
     2941 atcgtcaaag cattaaagat ttggcaccta atttccgtgt aactgctatt gattcaagag
     3001 accaaactat tgaagcgatt gagtctatcg acgagcaccg cattatcggt ttacagtggc
     3061 atccagagtt tctggttaat gaagaagatg gcaatttaga attatttgag tatttattga
     3121 atgaactgta acgattggaa catctggtcg ttctttcttt tattttttca aaatttttag
     3181 aatgtggcat tttacgcaaa cgtttgaatt atgataaaaa ttggagaaat tcgacaaaaa
     3241 aacttgaaaa aaacgaaggt aagcgttatg atagaaaaga agaaatattg gaggaagaac
     3301 atgtcacata ttaaatttga ttattcaaaa gttttagaca aatttgttgc accacatgaa
     3361 gtggaataca tgcaatcaca agtaacagca gcagatgaat tgatccgtaa aggaactggt
     3421 gctggtagcg acttcttggg atggttggac cttcctgaaa aatacgatcg cgaagaattt
     3481 gaccgcatct tgaaagctgc tgagcaaatc aagtcagaca gcgatgtttt ggttgtgatc
     3541 ggtattggtg gatcttacct tggtgcaaaa gcagcaatcg acttcttgaa tcaccatttt
     3601 gctaacttgc aaacaaaaga agaacgcaaa gctccacaaa tcctttacgc aggaaactca
     3661 atctcatcta cttaccttgc tgacttggta gagtatgttg cagacaaaga cttctcagta
     3721 aacgtaattt ctaaatcagg tacaacaact gaaccagcga ttgctttccg tgtctttaaa
     3781 gaactcttgg ttaagaaata cggtcaagaa gaagctaaca aacgtatcta tgcaacaact
     3841 gaccgccaaa agggtgctgt taaggttgaa gcagacgcta acggttgggg aacatttgtt
     3901 gttccagatg atatcggtgg acgcttctca gtattgacag ccgttggttt gcttccaatc
     3961 gcagcatcag gagctgacat caaagctctt atggaaggtg cgaatgcagc tcgcaaagac
     4021 tacacttcag acaaaatctc tgaaaacgaa gcttaccaat acgcagctgt tcgtaacatc
     4081 ctttatcgta aaggctatgc aactgagatc ttggtaaact atgagccatc acttcaatac
     4141 ttctcagaat ggtggaaaca attggctggt gaatcagaag gaaaagacca aaaaggtatc
     4201 tacccaactt cagccaactt ctcaactgac ttgcactcac ttggtcaatt tatccaagaa
     4261 ggaactcgta tcatgtttga aacagttgtc cgtgttgaca aacctcgtaa aaacgtgctt
     4321 attcctactt tggaagaaga ccttgacgga cttggttacc ttcaaggaaa agacgttgac
     4381 tttgtaaaca aaaaagcaac tgacggtgtt cttcttgccc acacagatgg tgatgtacca
     4441 aacatgtatg tgactcttcc agagcaagac gctttcactc ttggttacac tatctacttc
     4501 ttcgaattgg caattgccct ttcaggttac ttgaatgcta tcaacccatt tgaccaacca
     4561 ggtgttgaag cttataaacg taacatgttt gcccttcttg gaaaaccagg atttgaagaa
     4621 ttgagcaaag aacttaacgc acgtctataa tagaagaaaa gagtggtttg cccactcttt
     4681 ttactctctt tatccataga aattggactc agccaagact tgtgatataa tatagaaagc
     4741 aaaaaggcag acgcctagat aataggagaa actatgtcaa aagatatccg cgtacgttac
     4801 gcaccaagtc caacaggact actacacatc ggaaatgctc gtacagcatt gtttaattac
     4861 ttgtatgcgc gccatcatgg tggaacattt ctcatccgta tcgaagatac tgaccgtaaa
     4921 cgccatgtcg aggatggtga acattcacaa cttgaaaacc ttcgctggtt aggcatggat
     4981 tgggatgaaa gtccagaatc acatgagaat tatcgccagt ctgagcgttt ggacttgtat
     5041 caaaaataca ttgaccaact attagctgaa ggaaaagcct ataaatctta cgttacagaa
     5101 gaagagttgg cagctgaacg cgaacgccaa gaagtagctg gcgaaacacc acgctacatc
     5161 aatgaatacc ttggtatgag tgaagaagaa aaagcagctt acatcgcaga acgtgaagca
     5221 gcagggatca tcccaactgt tcgtttggct gtcaatgagt caggtatcta caagtggcat
     5281 gatatggtca aaggcgatat cgaatttgaa ggtggcaata tcggtggtga ctggattatc
     5341 caaaagaaag acggttaccc aacttacaac tttgccgttg ttatcgatga ccacgatatg
     5401 caaatctctc atgttatccg tggagatgac catattgcta atacaccaaa acagcttatg
     5461 gtctatgaag ctcttggttg ggaagctcca gagttcggtc acatgacctt gattatcaac
     5521 tctgagactg gtaagaagtt atctaaacgt gatactaata cacttcaatt tatcgaagat
     5581 taccgaaaga aaggttacct tccagaagca gtctttaatt ttattgctct tcttggttgg
     5641 aacccaggtg gtgaagatga gattttctct cgtgaagaac tcattaaact ttttgatgaa
     5701 aaccgcctca gcaagtcacc agcagccttt gatcagaaaa aactagactg gatgagcaat
     5761 gattatatca agaatgcaga ccttgaaacc atctttgaaa tggcaaaacc attcttagag
     5821 gaagcaggcc gtttgactga caaggctgaa aaattagttg agctctataa accacaaatg
     5881 aaatcagtag atgagattat cccattgaca gatcttttct tctcagattt cccagaattg
     5941 acagaagcag agcgcgaagt catgacgggt gaaacagttc caacagttct tgaagcattc
     6001 aaagcaaaac ttgaagcgat gacagatgat aaatttgtga cagaaaatat cttcccacaa
     6061 attaaagcag ttcaaaaaga aacaggtatt aaagggaaaa atcttttcat gcctattcgt
     6121 atcgcagttt caggcgaaat gcatgggcca gaattaccag atacaatttt cttgcttgga
     6181 cgtgaaaaat caattcagca tatcgaaaac atgctaaaag aaatctctaa ataaagagga
     6241 tacaataatg gacatctggg aaaagatgta cgaagaagca cagaaactat acaatccaca
     6301 tgaagtatca gactttgttt atgccaatca tgttgtagct gcagtagaag cagaagatgg
     6361 acaaatattt acaggattct gtatggaggg aacctgtggt gttttccatc tctgcgcaga
     6421 acgggcggcc ctcttcaata tgtaccaatt ttcaggacaa actaaggtta agaaagtatt
     6481 agcctttcga gacaaaccac cttatggtgg aagttcagcc atgccttgcg gtgcttgtag
     6541 agaattcctt ttagagctta atgctgaaaa taaagatgca gaattcatga tggactataa
     6601 tataagaaaa acagttaaag tcgcagaact aatcccttat tggtggggag aagaacgtgc
     6661 ttctaagttt aatgagcgat agaagagtca gtataattct ggcttttttt actataagtt
     6721 gaaaaaataa aaaaaaatta gaaaaagtag ttgacaaagt
//
LOCUS       DBERXF010000064         6646 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.64, whole genome shotgun sequence.
ACCESSION   DBERXF010000064 DBERXF010000000
VERSION     DBERXF010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6646
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.64"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(407..984)
                     /locus_tag="ACL8JK_002003"
                     /pseudo
     CDS             complement(407..984)
                     /locus_tag="ACL8JK_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
     gene            complement(1257..2099)
                     /locus_tag="ACL8JK_002004"
     CDS             complement(1257..2099)
                     /locus_tag="ACL8JK_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGS1786814.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYHAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(2213..3604)
                     /gene="pgdA"
                     /locus_tag="ACL8JK_002005"
     CDS             complement(2213..3604)
                     /gene="pgdA"
                     /locus_tag="ACL8JK_002005"
                     /EC_number="3.5.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050119 - N-acetylglucosamine deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-N-acetylglucosamine deacetylase
                     PgdA"
                     /protein_id="HGS1786815.1"
                     /translation="MDKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIELLKKEKDDQLSEGNQKEYFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKSFSDQDLSAWNFDYKDS
                     QIILYPSPVLENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(3842..4210)
                     /locus_tag="ACL8JK_002006"
                     /pseudo
     CDS             complement(3842..4210)
                     /locus_tag="ACL8JK_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            4431..5408
                     /locus_tag="ACL8JK_002007"
     CDS             4431..5408
                     /locus_tag="ACL8JK_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGS1786816.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQIPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            5405..6487
                     /locus_tag="ACL8JK_002008"
     CDS             5405..6487
                     /locus_tag="ACL8JK_002008"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS1786817.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     ILRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
BASE COUNT         1981 a         1468 c         1145 g         2052 t
ORIGIN      
        1 tctgccactg acgcagtgaa atgtcaattt cttagacatt gtttactcct ttttatataa
       61 attacttgcg acacgagtct gcctcgtcga tcatacgagg caagacgagt tagtactgcg
      121 tctagctcag gcactctagt gctgagcgta gggcagtccg actgtaagga ggtttctgcc
      181 actgacgcag tgaaatgtta atttcttaga cattgaatac tccttaataa aaaataattt
      241 cttgcgacac gagtctacct cgtcgattat acgaggcaag acgagttagt actgcgtcta
      301 gctcagcacc ctagtgctga gcgtggggca gtccgactgt aaggaggtct ctgccactga
      361 tgcagtgaaa tgtcaatttc ttagacattg tttactcctt tagtttttat atttcttttt
      421 caattaattt ctgctgaaca aaccaatcta acaagggaaa agttttttct gtatttgccc
      481 ataaatgata agaatctaag accgcttgta cactacctaa attttctacc aacttatcta
      541 ctgtcaaaaa gctgcgccag tattcataaa aaatacttgc atagttctta tcataagtcg
      601 aagaaccaaa atcattcaat gaatgccaac tatacttctt ctgaaaaagt tctacgagag
      661 attgattaca aattttttcc gcttgaaatt cctcttctgt caagaaatac ttgcgactaa
      721 tatattcaac catcccctct tcgaaccaga tataagagtc ataaccattc gtctattatt
      781 tgtataggct ggaacagcgc tttccctaat aatctgtgta gcagcattaa aatctgacca
      841 aataacggct tgcggtaaat cacagactgc aagttcattc tttaaaaaag attgataatc
      901 tttcaacttt tcagtatttc ttactacaaa atcacgaaat gtagctagtt gactatcgtc
      961 ttttacaaga taaaggttgt ccacggctct cctttctttc acacaataga ctgaataagc
     1021 aaaagaaccg cgtccgacaa tcctaggttg atttaaccta ggggcgtcag aaacgcggtt
     1081 ccaccctaat ttattacttc attgtttttg aaaatactac agaaagcgcc agctcattat
     1141 tttgccctac ttggctccca ctatcccaag ctcgcttgaa gaacgccata agactttctt
     1201 tcctgctgac tattatatca aaaattagaa taatgtacaa ttctttttat gattttctag
     1261 aaatccacat catcaactcg tggagcaccc gattgaacag caatcgtttt taaggtttct
     1321 ctctcctcat gactcagttc aattccaaag caatcaagat tagcttgaat acgagaggtt
     1381 gtgacagatt ttggaagtgg taaaaatcct tctgccaagc tccaggccaa ggctatctga
     1441 gcaatcgatt ttccgtgatt tgctgcgatt tcttgcactt gcttgctatc aaatagttct
     1501 ccctgaccaa aaggccccca agcttccaat aaaattccct tttcacgaca gtaagctacg
     1561 acttgatctt gatacacacc tggcgccaag cgaacttgat tgaccgcagg aacgatagtt
     1621 gcagtttcaa gcaaggcatc caaatgatgg ggaagaaaat tgctaacgcc gatagcacgg
     1681 attttccctt cttgatagag gtcttccatc gctctccaaa cttccgcatt gcgagttttc
     1741 catgcgtcat tttctctgag cggttttggg ttcggccaat gaatcaaata caaatccaaa
     1801 taatccaagc ccagtttttc tatagatttt tccaaagctt gacgagtttg ctcataggtt
     1861 tgctgactat tccaaagctt ggtagttacg aacatttctt cacgtggaac tccgctatct
     1921 ttgattgctt gaccaacact ttcttcattc tgataaatcg ccgccgtatc aatatgacga
     1981 taaccagcct tcaaggcttc taacactgca tgataggctt cttctccatc cttagcctta
     2041 aaagttccaa atcccaatac tggaatttct actccattat ttaattgata ggtattcata
     2101 tgcttctcct tctattttat tcatcaatta tagcataaga cattttttaa gtagtactat
     2161 cttctgtaaa aaataagtct gtcaaatatc taacagacct attttttctt gcttattcat
     2221 cacgactata gtacagctca tgagctttta ggcgagtatt gagcatctct ggtatggtca
     2281 caaaggtata accttgattt ttcaaatact caatgaccct tggcaaggca ttgactgtcg
     2341 gactgtgaat atcatgcatc aaaacgatag agccgttagc tacttgatgc tgaatttctg
     2401 tcaaaataga tgcttcattt ttactcttcc agtccagact atccacatcc cacatgataa
     2461 agctcaaatc caagctattg cgaatatcat ctgtaatagc accataaggt ggacgcatga
     2521 gtttagaact agaacccagc actttagtta gcacatcctc agtatcagta atctgctttt
     2581 tagcttcatc aagagagagt tgcgagagaa tcggatggct ccaactatgg tttccaacaa
     2641 catgaccttc agattttatc ctcttcacca agtcctcatt cccagaaaca tttttcccaa
     2701 gcacaaagaa agtcgcttta atatcatatt tagctagggt ctctaatacc tgcggggtcg
     2761 ttgctggatt tggaccatca tcaaaggtta gagcgacaac tttttgatat ttcttatcaa
     2821 agtaagattg atacaaggcc gcatcttttt cgagtaagta cgaagattgg ataacatcaa
     2881 agaaagcaga tactggcaag gctatctctt ctaaattttc aagcacagga cttggataaa
     2941 ggataatctg actatccttg taatcaaaat tccatgcaga caagtcttgg tcagagaagc
     3001 tttttacaat ctgctcactc tggtcttgct ctattttttt atcctctatg aaggaggtca
     3061 actcttttat cagctgttcc ttagccttac tagcatctga aaacagttgg tcaagtgtaa
     3121 aaggttgccc atcttctgtt aagtgaacct ttcctagact ggtcttttca gtctcttcaa
     3181 tcttaaaagc aactaaatca tagatttgtt tggtcacatt acgattaacg actcccttta
     3241 aacctgactc ttcttgctct gtatagtaga aaacaagatt gtccttactt tctagcttgt
     3301 ccttaacatc ttgatttatc agctccctaa cagaggaaat cactttctcc ccttggagag
     3361 ggtaataggc aatcacttcg gcttgcccct gacgaaaata ctccttctga tttccctcac
     3421 tcaattgatc atctttctct tttttgagca attcaatctt ttgctcaaaa cttttttgct
     3481 ggtagatctt aaaagcaata aatccgccta ataggcaaat agaaattgct aaaataccaa
     3541 tcaaagccaa taatacatgt ctcgttttcc cgtgtctgcc acgtcccagt ctacttttat
     3601 ccatatttat atcataacaa atttgagcaa taatttcaat gatacaattt ggcaatccac
     3661 aattcctcta gcaagccaaa gcatcttaca tcaactccaa catccgtatc tgtagagatt
     3721 atgtagtttt ctatctatgg aatttctagt agattgaagc tagaatagta gacctatact
     3781 tctaaaacat tgttagaaat cgatttgatt gtcctgatcg atttgtcctg ttctcatttc
     3841 attttactat aaaactatga aaagctaggt catctgagaa gtaattacta tcgacaattg
     3901 cgatagcgta tactagtgcg atttgtttgt agctctggtg ggtatcacct tcacgttggc
     3961 gaattttttc taggttttga ttaacctgac tgcacagata aggccatagg cgattgatga
     4021 aaaaattctg atgatgatcc tgaatttcga tgataacttg gattccatta tctaactccg
     4081 ccaagacgtc tatactagta tagaaatctt acgctgagta gggcatggaa ggcaagacgt
     4141 gaatgttact tccctccaaa atcgtcacat tttttgctgg caagtccagc atatcgcgga
     4201 taaattgaca aatcattagt tgggctgata cctggatgtc tgagaatcct ccttttcctc
     4261 cttctattat agcacatttt taaatctagg tttgctagat tctatgcttc tatctattta
     4321 ttcggaaaag aaagctaata gcttatttga aattttctcc tctctgttgg atagtcccgt
     4381 ctatctatgt tataatgaaa gaaggattta aaatcggaaa aggagtattt atgctaaaat
     4441 taggtgtcat cggaactggc gctatcagcc atcatttcat agaagcagcc cataccagtg
     4501 gagaatacca actggtcgca atctattcta gaaaactaga aactgcagca acctttgctt
     4561 ctcgctatca gaatatccaa ctattcgatc aattagaagt cttcttcaaa tcttcttttg
     4621 atttagtcta tatcgccagt ccaaactcct tacattttgc tcaggcaaaa gctgccttgt
     4681 ctgctggtaa acatgttatt ctcgaaaagc cagctgtcac tcaaccacaa gaatggtttg
     4741 atttgattca aacagctgaa aaaaataact gttttatctt tgaagcagct cgtaattacc
     4801 acgagaaagc ctttactact atcaaaaact ttttagcaga taagcaagtg ttaggagcag
     4861 atttcaacta tgccaaatac tcttccaaga tgcctgactt gttggctgga caaacaccaa
     4921 atgtcttttc agaccgtttt gctggtggag ccctcatgga tttggggatt tatcccctct
     4981 atgctgctgt tcgtcttttt gaaaaagcta atgacgcgac ttaccatgct caacagcttg
     5041 acaatagcat tgacctaaat ggagatggta tcctcttcta cccagactat caagttcaca
     5101 tcaaggctgg aaaaaacatc acttccaatc ttccttgcga gatttataca acagatggaa
     5161 ccttgactct caacacgatt gagcatattc gctcagctat ttttaccgac caccaaggaa
     5221 atcaagtcca gattcctatc caacaggctc ctcatacgat gactgaggaa gtcgctgcat
     5281 ttgcacacat gatccagcaa ccagatctga atctctacca aacttggctg tatgatgcag
     5341 gctctgttca tgagctacta tataccatgc gccagactgc tggcattaga tttgaggcag
     5401 aaaaatgaaa accaaactac cgactgaatg gcaagaactg agtgaccaac tcggtttcca
     5461 agaattcacc cccattcaaa ctcaactatt tgagcccctt cttgctggag aaaacctcct
     5521 aggagtgagc caaaccggaa ctggtaagac cctagcgtat ctcctaccaa gtcttctcag
     5581 actacaaaag aaaaaagccc aacaactctt gattctagca ccaaacacgg aacttgctgg
     5641 acagattttt gatgtatgta aaacgtgggc agaagctatc ggattgactg ctcaactctt
     5701 cctttcaggt tcaagtcaga aacgacaaat tgaacgtctt aaaaaggggc cagaaattct
     5761 gattggaact cctggccgta tctttgaact cattaaactt aaaaaaatca agatgatgaa
     5821 tgtggaaacc atcatcctgg atgaatttga ccaattacta gatgattctc agattcactt
     5881 tgtagaaaaa atcactcact acgcacctcg tgaccaccaa ctggtctaca tgagtgccac
     5941 gaccaagttt gatcaagaaa agattgtgcc gaatacacgc actattgatc tctctgatca
     6001 aaaattggac aatatccagc atttctacat gcaggtcgac caacgtcatc gagtggatat
     6061 actacgaaaa ctggctcatg tagaggattt ccgtggtcta gtcttcttca atagcctgtc
     6121 agaccttggg aatgccgagg aaaaactaca gtatcgtgat atattggctg tttccctcgc
     6181 tagtgatgtt aatgttaaat ttagaaaagt catcttagaa aagtttaaag ataaccaact
     6241 aaccctgctt cttgcaactg accttttggc tcgtggaatt gatatcgata gcctagaatg
     6301 tgtcgtaaac tttgatattc ctagagatag cgaaacctac acacaccgtg ctggccgtac
     6361 tggccgtatg ggcaaggaag gatatgttat tactctcgtc actcatccag aagaaatcaa
     6421 aaaacttaaa aagtttgcaa gtatccgaga aattgtccta aaaaaccaag aactctatat
     6481 caaataaagc cccattgctc tatacacatc cagtgtatgg agctttttta taagcaattc
     6541 aattttatac tcatctgctt tcaaaaagca ttctagtcca tctctgatta acgatggact
     6601 ttatcacctc cttctccagt ccttgtatga catcttgaag ttgatt
//
LOCUS       DBERXF010000065         6284 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.65, whole genome shotgun sequence.
ACCESSION   DBERXF010000065 DBERXF010000000
VERSION     DBERXF010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.65"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..161
                     /locus_tag="ACL8JK_002009"
                     /pseudo
     CDS             1..161
                     /locus_tag="ACL8JK_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            314..514
                     /locus_tag="ACL8JK_002010"
     CDS             314..514
                     /locus_tag="ACL8JK_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786818.1"
                     /translation="MVVSASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            539..956
                     /locus_tag="ACL8JK_002011"
                     /pseudo
     CDS             539..956
                     /locus_tag="ACL8JK_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane domain-containing protein"
     gene            1187..1894
                     /gene="ccdA2"
                     /locus_tag="ACL8JK_002012"
     CDS             1187..1894
                     /gene="ccdA2"
                     /locus_tag="ACL8JK_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGS1786819.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQERAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1905..2462
                     /gene="sdbB"
                     /locus_tag="ACL8JK_002013"
     CDS             1905..2462
                     /gene="sdbB"
                     /locus_tag="ACL8JK_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HGS1786820.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDVPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2836..4227
                     /locus_tag="ACL8JK_002014"
     CDS             2836..4227
                     /locus_tag="ACL8JK_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGS1786821.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4370..5287
                     /gene="adcAII"
                     /locus_tag="ACL8JK_002015"
     CDS             4370..5287
                     /gene="adcAII"
                     /locus_tag="ACL8JK_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HGS1786822.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5295..>6284
                     /gene="phtB"
                     /locus_tag="ACL8JK_002016"
     CDS             5295..>6284
                     /gene="phtB"
                     /locus_tag="ACL8JK_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HGS1786823.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANTAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELE"
BASE COUNT         1918 a         1139 c         1327 g         1900 t
ORIGIN      
        1 ctggaagaag atatcagagg atttctttgg ttgcaggtct aacaaatggt gagttaatcg
       61 ttccaatgac ttacgaagag acgatgacga gcgacttttt tgaagcttgg tttcagaagt
      121 ttttcttacc aacattaaac acaccatcgg ttattatagt aaaatgaaat aagaacagga
      181 caatcaaatc aatttctagc aatgttttag aagtccatat gtactattct agtttcaata
      241 taccataact gctcctagtc aacctgcaag tcctgtccca gctccaagct cagctccgac
      301 tcaagatcct agagtggtag taagcgcttc ggctagctca acgagcacac aagctcaaga
      361 gcaagttgac aagtctgaac ttcgtgcctt gagtcaagag ttagaccaac gcttgaaagc
      421 tttggcaaca gtatctgatc cgaaaatcga tgcaaccaag gctgtcctcc tagatgctca
      481 aaaagctccg gaagatagtg ccttgacaga gtaaggtctg catactgcag tagagtctgt
      541 gaagactgcc ttggactctc tcaaagatgt gatggcaaat gctagcgaca gcaagcctac
      601 acaggacaag aaggatgcaa aacaaggaac ggaagatagt aaggattcag ataagatgac
      661 tgaaacaaac tcagttccag caggagtgat tgtggtcagt ctacttgccc tcctaggcgt
      721 gattgccttc tggctaattc gccgtaagaa agagtcagaa atccagcaat taagcacgga
      781 attgaccaag gttctaggac agctagatgc agaaaaaagc ggataaaaaa gtccttgcca
      841 aagcccaaaa ccttctccaa gaaacccttg atttcgtgaa ataagaaaat ggctcagcag
      901 agacagaaac taaactagta gaggagctta aagcaatcct tgacaaactc aagtaaaaca
      961 tgatttatga aatgtcagac ctaaaagaca ttttcgttca caaaagcagc gacgagtaat
     1021 ccttgtcgtt gctttttggc tattttgggg gataagatcc gccttgacta gcaaaagaaa
     1081 agattggtcc aatagtgccc gatacgattt tgcgtagcag aaagcttaca aataaaattg
     1141 aatatagtaa aataggatta gaattattaa gaaagttggt tctttattgg aaacgatagt
     1201 atttttaatc tctgtttttc tagcaggtgt tttatccttt ttttctcctt gtatttttcc
     1261 tcttctgcca gtctatgctg ggattttatt ggatgatcaa gaaagggcaa aaagcttttc
     1321 tttgtttggg agaaaggttc tctggtcagg cttgattcga acactttgct ttatcgctgg
     1381 tatctctctc attttcttta ttctaggctt tggtgctggt tactttggtc atattctcta
     1441 tgcaaattgg tttcgatatg tcatgggagc tattattatc attttgggtc ttcaccagat
     1501 ggaaattttt catttgaaga aattagaagt tcaaaaaagt tttaccttta aaaaatcaga
     1561 ttctaatcgt tattggtcag cttttttact tggtattacc tttagctttg gttggacacc
     1621 ttgtattggt ccagttttaa gttctgtttt agcacttgcg gcttctggag gcaatggtgc
     1681 ttggcaagga gcgatttata ctctcattta cactctgggc atggcccttc ctttcttggt
     1741 cttggcacta gcttcaggtc tagtcatgcc atattttagt aaaatcaagc gtcatatgat
     1801 gctactaaag aaaattggtg gtttcctcat tgttttaatg ggaattttgt tactattagg
     1861 acaagtaaat gttctagctg gaatttttga ataaaggagg acaaatgaaa aaagtaatgt
     1921 ttgctggctt aagtctcttg tcattagttg tattgatggc ctgtggtgag gaagaaacta
     1981 aaaagactca agcagcacaa cagccaaaac aacaaacgac tgtacaacaa atttctgttg
     2041 gaaaagatgt tccagacttt acattgcaat ccatggatgg caaagaagtt aagttatctg
     2101 attttaaggg taaaaaggtt tacttgaagt tttgggcttc atggtgtggt ccatgcaaga
     2161 aaagtatgcc agagttgatg gaactagcgg cgaaaccaga tcgtgatttc gaaattctta
     2221 ctgtcattgc accaggaatt caaggtgaaa aaactgttga gcaattccca caatggttcc
     2281 aagaacaagg atataaggat atcccagttc tttatgatac caaagcaacc accttccaag
     2341 cttatcaaat tcgaagcatt cctacagaat atttaattga tagccaagga aagattggaa
     2401 agattcaatt tggtgctatc agtaatgcgg atgcagaagc agcatttaaa gaaatgaact
     2461 agaatcgata aaatctgatt acaagatgta gtcagatttt ggtaacttct aaaactaact
     2521 tccagtttcc cacaacctag cttttagtat gagaaaaacg cgtgacatca gtggaaatcc
     2581 gtcttagact aacttccact ggttttcttt ttcttgatat ataagggttc aaaagcgaaa
     2641 agactcagaa aaagtgcacg acaaatagcc ctaaaacaga gtcgtcttag agtaacttcc
     2701 agttttggga gagagatgga agttactttg agaagttacg gtagtcagat ttttttagaa
     2761 aaacatttta taaatattca catatctcct atatttatgg taaaatagaa ttatcagttt
     2821 attttggagt caaagatgaa tatatttaga acaaagaatg ttagtttaga taaaacagag
     2881 atgcataggc atttgaagtt atgggatttg attttgctgg gtatcggagc catggtaggg
     2941 acaggcgtct ttacaatcac aggtactgca gctgcaacac ttgctggccc agccctagtg
     3001 atttcaatcg ttatttctgc cttgtgtgtg ggattatcag ccctcttttt tgcagaattt
     3061 gcctcgcgag tacccgctac aggaggtgcc tatagttacc tctatgctat cttaggagaa
     3121 ttccctgcct ggttggctgg ttggttaacc atgatggagt tcatgacagc catatcaggc
     3181 gtagcttcgg gttgggcagc ttattttaaa ggcttgctct ctcaatacgg gatagccttt
     3241 cctcaggctt taaatggtac ctttaatcct caagcaggga catttgttga tttattgcct
     3301 attcttgtct tggtcttggt gacttcgctt gttttactaa atgccaaggc agccttacgc
     3361 tttaattcga ttctagttat tttgaaattt tccgctttag ctctctttgt tttagtagga
     3421 atttggaata ttaagtttga taattggagc aattttgctc cttacggttt tggacaaatc
     3481 tatggagcta gtactggtat tatggctggt gcatccttga tgttcttcgg ttttttggga
     3541 tttgaatcca tctctatggc tgtagatgaa gtcaagactc ctcaaaaaaa tattcctaga
     3601 gggattgtct tatcgctttc tatcgtaacc attctctatg ccttggtgac ccttgttttg
     3661 actggtgtgg ttcactatag tcatttaaat gtcgatgatg ccgttgcctt tgcccttcgt
     3721 agtgttggga ttagttgggc agccaactat gtgtcattag tggctatctt gaccttgatt
     3781 acagtttgta tttcgatgac ctatgcccta tcgcgtatga tttacagttt agcacgtgac
     3841 ggcttagtgc ctgctgcctt taaggaactg acgaagacta gcaagatacc aaagaatgct
     3901 actatcttga caggtctagc ttcagcagta gcagcaggaa tgttcccact agccagtatt
     3961 gcagcctttt taaatatttg taccttagcc tacttgatca tgttggctta tggtctgatt
     4021 cgcttacgga aagaaaaagg aatgcccaaa gctggggaat ttaaaacacc attggtacct
     4081 ctgttaccaa ttttatcgat catcatttgt ttatccttca tgttacagta taatatgaat
     4141 acctggattg ctttcctagt tgcgttgtta gtaggaagta ttatttactt cacttatggc
     4201 tataagcatt ctaccataga agaataaagt gaaagtctat tgagttgttg acactcagca
     4261 gatttttata tgtgaaagaa atttcaaatt ttttctaaaa atatcttgac agattaaatt
     4321 ttcaggagta gaatatttac tagttaatta aatggttaag gagttgttca tgaagaaaca
     4381 aaatttattt ttagtcctgt taagtgtctt tcttttgtgc ttgggggctt gtggtcaaaa
     4441 ggaaagtcag acaggaaagg ggatgaaaat tgtgaccagt ttttatccta tctacgctat
     4501 ggttaaggaa gtatctggtg acttgaatga tgttcggatg attcagtcaa gtagtggtat
     4561 tcactccttt gaaccttcgg caaatgatat cgcagccatc tatgatgcag atgtctttgt
     4621 ttaccattct catacactcg aatcttgggc aggaagtctg gatccaaatc taaaaaaatc
     4681 caaagtgaag gtcttagagg cttctgaggg aatgaccttg gaacgtgtcc ctggactaga
     4741 ggatgtggaa gcaggggatg gagttgatga aaaaacgctc tatgaccctc acacatggct
     4801 agatcctgaa aaagctggag aagaagccca aattatcgct gataaacttt cagaggtgga
     4861 tagtgagcat aaagagactt atcaaaaaaa tgcgcaagcc tttatcaaaa aagctcagga
     4921 attgactaag aaattccaac caaaatttga aaaagcgact cagaaaacat ttgtaacaca
     4981 acatacagcc ttttcttatc tagcgaagag atttgggctt aatcaacttg gtattgcagg
     5041 tatctctcct gaacaagaac caagtccacg acaactaaca gaaattcagg aatttgttaa
     5101 gacctataag gttaaaacga tttttacaga aagtaacgct tcttcaaaag tagctgaaac
     5161 tcttgtcaaa tcaacaggtg tgggtcttaa aactctgaat cctttagagt cagacccaca
     5221 aaatgacaag acctatttag aaaatcttga agaaaatatg agtattctag cagaagaatt
     5281 aaagtgagga aagaatgaaa atcaataaaa aatatctagc aggttcagtg gcagtccttg
     5341 ccctaagtgt ttgttcctat gaacttggtc gtcaccaagc tggtcaggtt aagaaagagt
     5401 ctaatcgagt ttcttatata gatggtgatc aggctggtca aaaggcagaa aatttgacac
     5461 cagatgaagt cagtaagagg gaggggatca acgccgaaca aatcgtcatc aagattacgg
     5521 atcaaggtta tgtgacctct catggagacc attatcatta ctataatggc aaggtccctt
     5581 atgatgccat catcagtgaa gagctcctca tgaaagatcc gaattatcag ttgaaggatt
     5641 cagacattgt caatgaaatc aagggtggtt atgtcattaa ggtaaacggt aaatactatg
     5701 tttaccttaa ggatgcagct catgcggata atattcggac aaaagaagag attaaacgtc
     5761 agaagcagga acgcagtcat aatcataact caagagcaga taatgctgtt gctgcagcca
     5821 gagcccaagg acgttataca acggatgatg ggtatatctt caatgcatct gatatcattg
     5881 aggacacggg tgatgcttat atcgttcctc acggcgacca ttaccattac attcctaaga
     5941 atgagttatc agctagcgag ttagctgctg cagaagccta ttggaatggg aagcagggat
     6001 ctcgtccttc ttcaagttct agttataatg caaatacagc tcaaccaaga ttgtcagaga
     6061 accacaatct gactgtcact ccaacttatc atcaaaatca aggggaaaac atttcaagcc
     6121 ttttacgtga attgtatgct aaacccttat cagaacgcca tgtggaatct gatggcctta
     6181 ttttcgaccc agcgcaaatc acaagtcgaa ccgccagagg tgtagctgtc cctcatggta
     6241 accattacca ctttatccct tatgaacaaa tgtctgaatt ggaa
//
LOCUS       DBERXF010000066         5756 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.66, whole genome shotgun sequence.
ACCESSION   DBERXF010000066 DBERXF010000000
VERSION     DBERXF010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5756
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.66"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..1504)
                     /gene="glpK"
                     /locus_tag="ACL8JK_002017"
     CDS             complement(<1..1504)
                     /gene="glpK"
                     /locus_tag="ACL8JK_002017"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGS1786824.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEID"
     gene            complement(1663..3090)
                     /locus_tag="ACL8JK_002018"
     CDS             complement(1663..3090)
                     /locus_tag="ACL8JK_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS1786825.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3255..4127
                     /gene="hslO"
                     /locus_tag="ACL8JK_002019"
     CDS             3255..4127
                     /gene="hslO"
                     /locus_tag="ACL8JK_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGS1786826.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            4114..5094
                     /gene="dusB"
                     /locus_tag="ACL8JK_002020"
     CDS             4114..5094
                     /gene="dusB"
                     /locus_tag="ACL8JK_002020"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGS1786827.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            5190..5756
                     /locus_tag="ACL8JK_002021"
                     /pseudo
     CDS             5190..5756
                     /locus_tag="ACL8JK_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1739 a         1320 c         1139 g         1558 t
ORIGIN      
        1 catcgatttc cgcaaagact tgagttgctt tcacagcctt cttccagccc ttgtagagtt
       61 gttccttgcg agattcgttc atagatggct caaagagttc tcctgtctcg ttcaagagtt
      121 tcaactcgtc caagtctttc cagtacccta ctgacaaacc tgctaggaag gccgctccta
      181 gagctgttgt ttccaggttt ttagcacgtg caatgtcaat gcctaaaata tccgcctgga
      241 actgcatgag gaagttgttc atggctgcac caccatccac cttcagtact tgaatggcgg
      301 tctgagtatc cacttgcatg gtgtcgatga tatcacgcac ttgataagca atagattgca
      361 aagtcgcctt gataaagtct tctttgcttg ttccacgagt caaaccaaag acggaaccac
      421 gagcattttg gttccagtat ggagcgccta gacctgtaaa ggctggaacg acataaactt
      481 catcgttgtt gtgagaatca cgagcgtatt tttcagattc tggtgaattt tcaaccatgc
      541 gaagaccgtc acgaagccac tgaatagcac ttcctgcgat gaagatagaa ccttccaagg
      601 cataataaac cttaccgttg attccgtaac caatggttgt caagaggttg ttttcagaca
      661 actgcatctc ttccccagta ttcatgatga tgaaagagcc tgttccataa gtattcttaa
      721 ccatacctgg ctcaaaagcc aactgtccaa agagggctgc ttgttggtcc ccagccatac
      781 ctgagattgg cacctctcca ccgtagaaat ggaatggagc tgtcttgccg tagatttcgg
      841 agttagaacg aacttctgga agtatagcct tcggaatgtt aaggatttcc aaaatctcat
      901 catcccattt gagttcttta atgttataaa gcatggtacg agctgcattt gagtagtcag
      961 tcacgtgagc cgcaccgtca gtcaatttcc aaaccaacca agtatcgata gtaccaaaga
     1021 gcaattcccc tttttctgct cgctcttgag caccttctac atgatccaaa atccaacgaa
     1081 ccttggtagc agagaagtaa gcatcaataa tcaaaccagt cttttcatgg aatttttcca
     1141 cataaccttg gctttttagt tgctcagcca aaggtgctgt ctggcgtgac tgccaaacga
     1201 tagcattgta gataggaagt cctgttttct tatcccagac aaccgttgtt tcacgttggt
     1261 tggtaatccc gattgcctcg atttgatttg gcttgacacc actttcgatg aaagcacccg
     1321 caataactga ctgaacagag ttccaaattt cattggcatt gtgctcaacc caacctgcct
     1381 gagggaaaat ctgggtaaac tctttttgac tcgagctaac cttttcccct tttttgttga
     1441 aaatgatggc acgagaactt gtagttccct ggtcaatggc catgatgtat ttttcttgtg
     1501 acatgtactg tcctcctgat aaagatcttg aggtatttcc tctttgcact tactagtata
     1561 caaaataaag cgctttcttg tttatcaact ttttttaatt tttaaaaaaa tgtgaggaga
     1621 ttgtgtgaat ttcacaaaaa agacctggat taaccaagcc ttttaagtga ataataactg
     1681 acgaatccct gccaaatctt ccatatccaa gtcatttttt aaataataga ctggggtctg
     1741 ttccttctta tgaatcgggt tattggtaac cagcaaatca taatgccgac tagggtcata
     1801 agcttcaatg gtaataaaac gattgtattc caaataccgt ttcaaaatgg ctgccatcct
     1861 tgaaaaaaca agaaaaccag atgtcaaatc cagaccaatc cgcatatgct ggccaccgtt
     1921 ttcagccata tattcgatta actggagcca ttcccagaga atcttcttat ctaaatctgt
     1981 cccctgttga aaagcaggta gagcatgaaa aatctcctct gctgtctctt taaaatcatg
     2041 ttccatcagt aaatatggat gacgattctc taactggtac ttgtagcgat cctgtaaaat
     2101 atagccctta tagagataga cttgagcaca aagctgactg agttcatagg tgacatggtc
     2161 ctctgtataa tcccccaata gttcctcctt cttcatttct tgaatcaatt gcgtcagtaa
     2221 atctgccaac tgccctccaa aaccaagaat atactccata gtatgaagag gaagaatgcg
     2281 atgagatagg agaaaagaga agaatatcat catctcacca tcctcaactc ctagtggaat
     2341 atgttgccca gcaaaaaagg acggaacctt tctcagcaaa cgaaggtaga aaatattgtc
     2401 aaaataccct cgcattttct cttctatgac ttgaaactga caagcattga cccgaagacg
     2461 ttgttgactg atgtgagccc agagaaccaa gtccaatttc tgccccacag acaaacttgc
     2521 accgcagatt tcctctaaat tggcaatctc ctgttttctc tctggtttct gcatgtgacc
     2581 ttcccattcc tgactcgacc agacctttcg gaaaagacag aaatagaaat agcgaatctg
     2641 atgctctgga cctcgccaac gtccattttg gatggataaa tcaaattctg acaaaatctg
     2701 atttaaacca gccaagtgac gaccaagcgt agcctcgcta atcaccaatt cttgagccag
     2761 ctgatgggct aaaaactgtt ggtggtagag aagataaacc aaaatctggt atttaacagc
     2821 actctccaaa aacaagctcc gaatatctct ccccttggta gctgcaccga tagacagacg
     2881 cagattttca tcttctgagt gaatagtcag ttctaagcca ctatccaaag ccttgtcatt
     2941 gagcagggtg acatatttgg ttagggttgc ttttgaaaat cctgtttctt ccattacagc
     3001 cttgacggtc gtctgagact cttgtaatag aaaggaaagg attgaaaatt gaccacactc
     3061 ggctttctcc atcaaatctc ctaaatacat ttgttacccc tttcattttc taccttaagc
     3121 atagcataaa tcttacaaat gctaaaataa tctgtttctc tttttatttt catgctgatt
     3181 tcctggtcca ttatcctgaa aatcagtaaa cacacggctc cccctttggg catttttatg
     3241 ctaaaatagt agctatggat aaaattatta aaactatatc agaaagcgga gcctttcgtg
     3301 cttttgtcct tgacagcacg gaaaccgtcc gcactgctca agaaaaacac caaacccaag
     3361 ctagctcaac tgtagcgctt ggtcgaactc ttatcgctag ccagattctc gcagccaatg
     3421 aaaaaggaaa taccaaactt acagttaagg tgttgggatc tagctctcta ggtgctatta
     3481 tcaccgtcgc tgataccaag gggaacgtca aaggctacgt tcaaaatcct ggtgttgaca
     3541 tcaaaaagac tgcgactggt gaagtcctag tcggaccttt tgttggaaat ggtcaattcc
     3601 tcgttatcac agactacggt actggaaatc cttacaactc tataactccc ctcatctctg
     3661 gagaaatcgg tgaagacctt gccttttacc ttactgaaag ccaacaaacg ccttcagcgg
     3721 tcggcctcaa tgtccttttg gacgaggaag acaaggtcaa ggttgcaggt ggtttcctag
     3781 ttcaagtctt gccaggagcc aagaaagaag agattgctcg ctttgaaaaa cgcatccaag
     3841 aaatgccagc tatctctact cttctcgaaa gcgacgacca tatcgaagcc ctcctcaagg
     3901 ctatctacgg ggacgaagcc tacaagcgtc tttctgaaga agaaatccgt ttccaatgtg
     3961 actgtagcca tgaacgcttt atgaacgctc ttgccagcct tccaagctca gacttacagg
     4021 aaatgaaaga ggaagaccac ggggcagaaa tcacttgtca attctgccaa actacttaca
     4081 actttgatga aaaggacctg gaggaactca ttcgtgacaa atcttaatac accttttatg
     4141 attggcaatg ttgagattcc caatcgtacc gttttagcgc ctatggctgg cgtgaccaac
     4201 tcagcctttc gtaccatcgc aaaagagctc ggagctggac tcgttgtaat ggaaatggtc
     4261 tctgacaagg gaatccaata caacaacgaa aaaaccctgc acatgcttca tatcgatgag
     4321 ggcgaaaacc ctgtctctat ccaacttttt ggtagcgatg aagacagcct agcacgcgca
     4381 gcagaattca tccaagaaaa caccaagacc gatatcgtcg atatcaacat gggctgccct
     4441 gtcaacaaaa tcgtgaagaa cgaagctggt gctatgtggc tcaaggatcc tgacaagatc
     4501 tactctatca tcaacaaggt ccagtctgtc cttgatatcc cacttactgt caaaatgcgt
     4561 accggctggg cggacccatc tctggcagta gaaaatgctc tcgctgctga ggctgcaggt
     4621 gtttctgccc tcgccatgca tggccgtacc cgtgaacaaa tgtatactgg ccacgcagac
     4681 cttgagaccc tttacaaggt tgcccaagct ctaaccaaga ttccattcat cgccaacggt
     4741 gatatccgta ctgtccaaga agccaagcaa cgcatcgaag aagttggtgc tgacgcagtc
     4801 atgattggcc gagctgccat gggaaatcct tacctcttca accaaatcaa ccattacttt
     4861 gaaacaggag aaatcctacc tgatttgacc tttgaagaca agatgaagat cgcctacgaa
     4921 cacttgaaac gattgattaa cctcaaagga gaaaacgtcg cagttcgtga attccgcggc
     4981 ctcgctcctc actatctccg tggaacatct ggcgctgcca aactccgtgg agccatttcg
     5041 caagctagca ccctagcaga gattgaagcc ctcttgcaat tggagaaggc atagtcttac
     5101 atctacaact cagaaaaacg gcaaagctca aaatgaacta ccccaaaaaa gttagacaga
     5161 aaaaatctaa cttttggggt gtttttatta tgaaactaac ttatgatgat aaagttcaga
     5221 tctatgaact tagaaaacaa ggatatagct tagagaagct ttcaaataaa tttgggataa
     5281 ataattctaa tattaggtac atgattaaat tgattgatcg ttacggaata gagttcgtca
     5341 aaaaaggaaa aaatcgttac tattttcctg atttaaaaca agaaatgatt aataaagtct
     5401 tacatgaagg ctgaactaaa gatagagttt ctcttgaata cggcctccca agtcgtacga
     5461 tacttcttaa ttggctagca caatacaaga aaaacgggta tactattgtt gagaaaacaa
     5521 gagggagagt acctaaaatg ggacgtaagc cacaaaagag acctgaagag aggacagaat
     5581 tagaacgtct tcaagcagaa aatgagtacc tgagagcgga gaatgctatc ctaaaaaagt
     5641 taagagaact ccgatggaag gaggaaaaag agaaagaaga aagacagaaa ttgttcaaga
     5701 attaatgact gagttttcgt tagatattct tctaaaagcc attaaactag ctcgtt
//
LOCUS       DBERXF010000067         5230 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.67, whole genome shotgun sequence.
ACCESSION   DBERXF010000067 DBERXF010000000
VERSION     DBERXF010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5230
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.67"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(244..636)
                     /locus_tag="ACL8JK_002022"
                     /pseudo
     CDS             complement(244..636)
                     /locus_tag="ACL8JK_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269502.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase domain-containing
                     protein"
     gene            complement(653..1459)
                     /locus_tag="ACL8JK_002023"
     CDS             complement(653..1459)
                     /locus_tag="ACL8JK_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS1786828.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(1665..2306)
                     /locus_tag="ACL8JK_002024"
     CDS             complement(1665..2306)
                     /locus_tag="ACL8JK_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS1786829.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(2303..4411)
                     /locus_tag="ACL8JK_002025"
     CDS             complement(2303..4411)
                     /locus_tag="ACL8JK_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGS1786830.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(4463..4714)
                     /locus_tag="ACL8JK_002026"
     CDS             complement(4463..4714)
                     /locus_tag="ACL8JK_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGS1786831.1"
                     /translation="MVCSILASTSVLAVWVDGGQWNYGVGWSGNFGYSDYLHSTRSHT
                     ATVKDGNKFSKDRAEAEAWARASLTKIPPTGMEYFYGFE"
     gene            5141..5230
                     /locus_tag="ACL8JK_002027"
                     /pseudo
     CDS             5141..5230
                     /locus_tag="ACL8JK_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
BASE COUNT         1625 a         1159 c          831 g         1615 t
ORIGIN      
        1 ccagaagttt ttagctctgc caagccacat agtgtgttta ctactatgtg gccatgtcac
       61 catgaatcgc cgaacaattt aacgagaaag tatgactttt acgtttatcc caactcaatt
      121 atgacatttt tttcaaaagt caatatatct cactttttca acgacaagaa agaggctgcc
      181 aattgaccac cctcttattc tgaacccatc actccatcac tttttagctt cattcgcttt
      241 cttagcgact gcaatctggt attcgacttg gtcattcccc ttacctgtac aaccatgagc
      301 aattgtagtc gctcctgtct gatgcgctat ttcaaccaat tttttagaaa taagagggcg
      361 gctcaaggca gataccaagg ggtacttttg ttcatagtag gcatgtgact ggagagctac
      421 tagcacataa tctgtagcaa attcgtcctt aacatcaatg acataagatt cgactgcccc
      481 aaccttaaga gccttatcat ggatgaaatc taagtctttc ccttcaccca catccataca
      541 aactgcaaca acatcatagt ctttcttcag ccaggtaata gcaactgatg tgtctaaacc
      601 gccagaatag gccaaaatta ctttttcttt actcatgttc ttttccttct ttctattttt
      661 caatggacgc tttaaaggca tcctcaatga gtttgtctaa ttccccagac tccttcaact
      721 tttgaatggt tttatcgact gcctctttca attccttgct atcttttttc atggctaccg
      781 cataggaatc atcttgctct ttttcaaaat tgaggtctgc gattgctaaa tcaggattat
      841 tttccacaaa tcccttggca acgggttctt caaaaataac ggcatccact tgccctgatt
      901 ttaaatctgt gattaaattc ccatttttag gcagagatac gagggaagaa ttttgtagca
      961 aatctttcgc catcgtctct tgaatcgaac ctttctgcgc tccgaccttt ttctgcgcca
     1021 aatcgttgac agactgataa gtggctaaat cagatttttt gacaatgagt ttattttttg
     1081 cagtatagta gggagttgaa aaatcaaaca ccttgctccg ttcatctgtc ttagaaacac
     1141 ctgatatggc aaggtcagct tttcctgatt gaacgctagc cagtacattg tcaaaactca
     1201 taggagatag ttccaattcg acacctagtt ctgttgcgat agccttggct aattcgatat
     1261 ctgaacccac aatctgattt ttcccatcaa ccactttttg atattcaaat ggagcaaaat
     1321 ctggattgag ggctacaacc aattttcctt tggacttgat ggcttcaatt ccagccgatt
     1381 gattgttact acaagcaaat agtaggggga gcatcactaa accaaacatc gtcatcaaca
     1441 ccttcttcat cttattcata acaaagcctc ctttatgttt attctttttt attgtataaa
     1501 taatactcct atactcatcc tttgtcaagc ctaaattgaa aaaattttca atttgaaaca
     1561 aaaaaaccta gaaatactac ataaaatgtc attcctaggc gtatttatgc catttttctc
     1621 tggaaaacat gagtattcag ccagtcaaaa ggagctgaat gaactcattt tccctcgccc
     1681 aattcaatga cacgatgaca ttgttgggct acataagcat cgtgggtcac aataatgact
     1741 gttttccctt ctcgattcat ctctaagaga aacttcaaga ccaaatctct attttcagga
     1801 tccagcgaac ctgtaggttc atcggctaaa atcagctggc tgggttttaa gatggctcta
     1861 gcaactgcaa ttcgttgttg ttcgccccca gacaactcgg agaccctttg atgcaaagta
     1921 gctgacaaac ctactctctc taaaatctct tccacctttt tgagcttgtc tttcttaggc
     1981 aatttcacat atttcagcgc cagcatgaga ttgtactcga ccgtttcatc atcaatcagg
     2041 gcaaaatttt gaaacagata agagatatgt tcacggatta ttgtttgcga cttagcagaa
     2101 ttaaccgcta gatttgtctg accaaaaatc tcataccgtc cgctataatc accatctatc
     2161 aaacccaata aatttaacaa ggtcgacttc ccactaccac tcttaccaac aatagctacc
     2221 aaatccccct gatcaatcct gagagataag ttatccaaaa tcacttttcc cccaatggtt
     2281 ttggtaatat ttttcaactc aatcataaga tgcccccttt caataactct actagacttc
     2341 ttttctccat cctagaagct aagcctagca caaatagtat atccagacat gtaaaacctg
     2401 caaacagtag aagtggtaag aacgcatggg caaagaaaat caagactaga agagggaaac
     2461 tatagcccag caagagcaga acgaggagag gacggtagcg atcgaccagt ttccacccca
     2521 taaacttctt ggtaatgata tccctgcgct tcaataagaa agttgttact agtaagaagt
     2581 aggaaatcat catgctaagg agaccaaaca aagcaaagag taggttaaaa ttccgaacag
     2641 catctctata agaatccact ttctcttgtt gaatggcttg aatagatgaa aattttaaat
     2701 aatttccatc tgacaatttc tcaactaact ctgtaatctc tttttgatgt tgaaccgtat
     2761 tttcaatttt aatcggatta tttaagccag ttgttgacag ggaggctttc tcatcccaca
     2821 tcatatcaga atcattgacc aagctaataa ttggattgga gagattttcc tttcgcttat
     2881 cactatatgg gaaaaatgac caatctcctt cataataggc aatctcgaca tccatctcct
     2941 ctatcgttcg tttttgctgc tcttcatact tcatcgaatg aaaggcaatt aacttcccca
     3001 agagctgatt tttatcttct tcacctttcg tacttgctgg catcaaaata acttttttaa
     3061 taccggtatc tggtagcttg aatcccttgc tctttagaaa attgcgattg gcatagtaaa
     3121 catccaccgt atctgttaac tgatattgct gaatctgttc tgattggaca aaatttttta
     3181 caggaagact gctactctgc acatagcccg cctgcgtttt ttctaccaaa tcctgataaa
     3241 atcgatagaa ataatctgta gatttccctg accctgctag ctcttcttgc cacagattat
     3301 cattgagttt gaaggtttct aaggtcaggt aattaccttg acttacccac tgttgctgat
     3361 aagcaagttc tttgttttct tgttctaaac ttctgcccac cccaatcagt aaggccgtca
     3421 gtaaaatagt tgtccctatt ttcatcacat aattgaagat aagaccaaat ttgaaagatg
     3481 aaaaaccttt cagcagagag ctgattgtca ttttttggat taagaggtaa gtcaaccaac
     3541 tgataaagag ataaagctgc aacagcaaaa aatgagacaa ccacagcata ggaaacaaat
     3601 cttttggctt ataatcaagc aagaaaaaca cgcctagatt gatcacaaga gccccaccta
     3661 ggaggaggta aaggttgcct tttacaacat cagctaaaac agccctatct tgaaaaccaa
     3721 gtaatttttg taccccaact cttttcatct ccatcatcgg ttgatacact gtcactaaca
     3781 caagaagcaa aatagccaag acaaaaacaa tggcagataa aagcaaatct cgatttatga
     3841 cttccactgc acttttgtag gtcggctcta gcaaggtagc ctggtctatc ttgaaaaaat
     3901 cgctccattt ctgtacaatc ctatccttgt ccatctcttg tgtagaagtt atcgtatagc
     3961 gaccatttaa actacgagat gtatccttga tataggtttg aaaagtcata agctgaatag
     4021 gtttggcttt tagaaaggtc ggaatcgtac caagtttatt ggaaatttct ttattactat
     4081 agactccttc accatctgtg gtaaaatcaa gagaagaaat cccaaactct tggtagggga
     4141 aggtatcttt atcaaaaaca ccagacttga ccacctcatc accactgtct gttttgatga
     4201 tggagacttt atactccttt gatacatcct caaaaaatcg aagaacagac gctgcaggtt
     4261 cgttaatatc tttcaaatac aaatccaaag aatctacagt ctttcccatt tcttgaatcc
     4321 gaaccacttc tcgtgtatag tttacattaa aaacaaaaaa agtggtacac agaagcagga
     4381 gtaacataca gaaattactg atttttttca taaaagtgcc tccactacag ttttccctct
     4441 ccaaatagga gagggaagaa ttttactcaa atccatagaa atattccatt cctgttggcg
     4501 gaatcttggt gagggaagct ctagcccatg cctcagcttc tgcacgatcc ttagagaatt
     4561 tatttccatc tttaacagtt gctgtatgag agcgagtaga atgtaaataa tcagaataac
     4621 caaaatttcc tgaccatcct actccatagt tccattgacc accatcaacc catactgcca
     4681 aaacacttgt agaagcaagt atactacata ccattaaaga tgcaacacta attttctcat
     4741 gatttatttc tcctattatc gagagctatt ccgtagaaac agctatagta atttgtcaac
     4801 aagtatcgta gtccattgga ctcaccttcc ttctatctca tttcattttt aaacaacgaa
     4861 cttactctta actaggagaa tagttctctt ctgtatcagg tctttgaaca accagagtag
     4921 tattaatcac actctaacta ttactcaaga atcagcccaa taaacaatat ggatagcgct
     4981 ttcaaacttt taaactctta tcccatcctt ttatctatat aataagtgaa aatataataa
     5041 ctgtcaagta atcgaagtga attttataaa aaaaattaca agccaaattt gcaaagttta
     5101 caataagccg ctagggcaat cgtctatcag aatgtccgtt tatttgtcaa taatccgaga
     5161 aaatcttgca acgcttagaa gtctataaaa actatcaaca tttatatgac ttgcgaatag
     5221 caatcctgct
//
LOCUS       DBERXF010000068         4785 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.68, whole genome shotgun sequence.
ACCESSION   DBERXF010000068 DBERXF010000000
VERSION     DBERXF010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4785
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.68"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            41..1867
                     /gene="glpO"
                     /locus_tag="ACL8JK_002028"
     CDS             41..1867
                     /gene="glpO"
                     /locus_tag="ACL8JK_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGS1786832.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKSDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            1937..2641
                     /locus_tag="ACL8JK_002029"
     CDS             1937..2641
                     /locus_tag="ACL8JK_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGS1786833.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            2938..3141
                     /locus_tag="ACL8JK_002030"
     CDS             2938..3141
                     /locus_tag="ACL8JK_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786834.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(3228..3836)
                     /locus_tag="ACL8JK_002031"
     CDS             complement(3228..3836)
                     /locus_tag="ACL8JK_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786835.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            3968..4159
                     /locus_tag="ACL8JK_002032"
     CDS             3968..4159
                     /locus_tag="ACL8JK_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786836.1"
                     /translation="MLNAKIFYIFLCLIVIETTGLLLLKRGLEMGYLDTEAIILAVFS
                     FAFYNLCSFAWVCSTIKNK"
BASE COUNT         1447 a          950 c         1046 g         1342 t
ORIGIN      
        1 actggcagaa taaagcgatt tagttagaaa gtgtgtaaat atggaatttt caaagaaaac
       61 acgtgaattg tcaattaaaa aaatgcagga acgcaccctg gacctcttga ttatcggtgg
      121 aggaatcaca ggagctggtg tagccttgca ggcggcagct agcggtcttg agactggttt
      181 gattgaaatg caagactttg cagaaggaac atctagtcgt tcaacaaaat tggttcacgg
      241 aggacttcgt tacctcaaac aatttgacgt agaagtggtc tcagatacgg tttctgaacg
      301 tgcagtggtt caacaaatcg ctccacacat tccaaaatca gatccaatgc tcttaccagt
      361 ttacgatgaa gatggagcaa cctttagcct cttccgtctt aaagtagcca tggacttgta
      421 cgacctttta gcaggtgtga gcaacacacc aactgcgaac aaggttttga gcaaggatca
      481 agtcttggaa cgccagccaa acttgaagaa ggaaggcttg gtaggaggtg gagtgtatct
      541 tgacttccgt aacaacgatg cgcgtctcgt gattgaaaac atcaaacgtg ccaaccaaga
      601 cggtgccctc attgccaacc acgtgaaggc agaaggcttc ctctttgacg aaagtggcaa
      661 gattacaggt gttgtagctc gtgatctctt gacagaccaa gtatttgaaa tcaaggcccg
      721 tctggttatt aatacaacag gtccttggag tgataaagta cgtaatttgt ctaataaggg
      781 aacgcaattc tcacaaatgc gcccaactaa gggagttcac ttggtagtgg attcaagcaa
      841 aatcaaggtt tcacagccag tttactttga cacaggtttg ggtgacggtc gtatggtctt
      901 tgttctccca cgtgaaaaca agacttactt tggtacaact gatacagact acacaggtga
      961 tttggagcat ccaaaagtaa ctcaagaaga tgtagattat ctacttggca ttgtcaacaa
     1021 ccgctttcca gaatccaaca tcaccattga tgatatcgaa agcagctggg caggtcttcg
     1081 tccattgatt gcagggaaca gtgcctctga ctataatggt ggaaataacg gtaccatcag
     1141 tgatgaaagc tttgacaact tgattgcgac tgttgaatct tatctctcca aagaaaaaac
     1201 acgtgaagat gttgagtctg ctgtcagcaa gcttgaaagt agcacatctg agaaatattt
     1261 ggatccatct gcagtttctc gtgggtctag cttggaccgt gatgacaatg gtcttttgac
     1321 tcttgctggc ggtaaaatca cagactaccg taagatggct gaaggagcta tggagcgcgt
     1381 ggttgacatc ctcaaagcag aatttgaccg tagctttaaa ttgatcaatt ctaaaactta
     1441 ccctgtttca ggtggagaat tgaacccagc aaatgtggat tcagaaatcg aagcctttgc
     1501 gcaacttgga gtatcacgtg gtttggatag caaggaagct cactatctgg caaatcttta
     1561 cggttcaaat gcaccgaaag tctttgcact tgctcacagc ttggaacaag cgccaggact
     1621 cagcttggca gataccttgt cccttcacta tgcaatgcgc aacgagttgg ctcttagccc
     1681 agttgacttc cttcttcgtc gtaccaacca tatgctcttt atgcgtgata gcttggatag
     1741 catcgttgag ccagttttgg atgaaatggg acgattctat gactggacag aagaagaaaa
     1801 agcaacttac cgtgctgatg tcgaagcagc tctcgctaac aacgatttag cagaattaaa
     1861 aaattaagaa aaaataaaag aggtggaggg cagcattcct tgtcgcccgt cccttctttt
     1921 taatggagac agaaagatga tgaatgaatt atttggagaa tttctaggga ctttaatcct
     1981 gattcttcta ggaaatggtg ttgttgcagg tgtggttctt cctaaaacca agagcaatag
     2041 ctcaggttgg attgtgatta ctatgggttg ggggattgca gttgcggttg cagtctttgt
     2101 atctggcaag ctcagtccag ctcatttaaa tccagctgtg acagttggtg tagctttaaa
     2161 aggtgacttg ccttgggctt ccgttttgcc ttatatctta gcccagttcg caggggccat
     2221 gctgggtcag attttggttt ggttgcaatt caaacctcac tatgaggcag aagaaaatgc
     2281 aggcaatatc ctggcaacct tcagtactgg accagccatc aaggatactg tatcaaactt
     2341 gattagcgaa atccttggaa cctttgtttt ggtgttgaca atctttgctt tgggtcttta
     2401 cgattttcag gcaggtatcg gaacctttgc agtgggaact ttgattgtcg gtatcggtct
     2461 atcactaggt gggacaacag gttatgcctt gaacccagct cgtgaccttg gacctcgtat
     2521 catgcacagc atcttgccaa ttccaaacaa gggagacgga gactggtctt acgcttggat
     2581 tcctgttgta ggccctgtta tcggagcagc cttggcagtg cttgtattct cacttttcta
     2641 gtttatactc ttcgaaaatc aaattcaaac cacgtcagcg tcgccttacc gtactcaagt
     2701 acagcttgcg gctagcttcc tagtttgctc tttgattttc attgagtatt agaaaacaat
     2761 tattttgata gagcttgggc aagagcccaa tttcagcaaa aaatgaagta aatcttctca
     2821 taataaaacg catcatatca agcacgaaaa ttccacgagg tcaactacag tcagaaagct
     2881 gaacaacaag ccaaaacgcc caaaaaaggc ggcaaaaagc aagcacctgc aagcaacgtg
     2941 ccgaaatggt caaatcctga ttatgtcaac gaattagacc caaaaatcgt tgatatgcta
     3001 gtagaatttc acaagtcaca aggcactttg gaaactcccg aggcgcaagc agaaatcgcc
     3061 caaaaacgtg aagaaatcga gcaaaggaga gctgagcttg aggataaaaa acaagagctt
     3121 ttgaaccgct tgaacaaata gagtttcgca agtattatgc ttacaaatta cttgagcaat
     3181 taactaaaat ataaaccctg cctttatatc taggcagggt ttatatttta gaaattcacg
     3241 taggttgtta cggtttttac atacccagta tagtttgagt ttctatagta ttcagtgata
     3301 aacttccatt ttctttgagc aacatggata taagtacttg ttatgtagta tggatatggg
     3361 ctttgtgaat ccaagtaaga ctgataagct tgtataccaa aatatgctcc accaattatt
     3421 gcaccccatg gaccccccaa taaagcacct atcctaccaa tcatataact gattccagca
     3481 ccagtcatga agttagcgaa tgtgttagct tgtttattcc catgtattgt gttgacgtaa
     3541 ttccaaacat taggatcgta tgatctaaaa gatatattta ggtcgatttc attcttttga
     3601 taagccatat aaaatgcccc attgatatag acgccgtcag cacgtcgttc aatagtgtct
     3661 acacttccat ctggattgac aacctcaaga acttcatcgc ttaaaatatt tacttgcgta
     3721 tctccgaacc gcactgatga gccattctca aactgagcct caccagatac aactttagag
     3781 tttgccgata agctatcatc agcaaaaaca acaagcgacg gggaaatgct agacatacag
     3841 aaaacagaca taactagcaa acacatgcat ttaaacatct tagacataac ggaaactctt
     3901 ttgtattttt gatttttttc aacttttatt atacaataaa accaaataaa aagaaagcgg
     3961 taacaatatg cttaatgcga aaatttttta tatattttta tgtttgatcg ttatcgaaac
     4021 tacaggcttg ttgttgttga aaagaggtct cgaaatgggt tatttagaca cagaagctat
     4081 tatcctcgca gttttttcat ttgcttttta caacctatgt tcattcgctt gggtctgctc
     4141 tacaataaaa aataaataga cgtattttca aaaaaaaaat gcatatttat attagcaaaa
     4201 tgacgattta aatcgtcgtt tttttgtagt acgacgggca tgtcgtatat ctgaggtgta
     4261 agtcctcggt gggcacctgc taccggtgaa cccaatagcg attcccaagc ctgactatcg
     4321 tgaggtagca gggagaggaa gggatagcga aatcgtggct ctacgaacag gaacgtgata
     4381 gtaaggcgta tatagcggat aaggaggctt caaactctaa agtccaaaaa ggtagtcgta
     4441 acctatatgt gtaaatcacg agagtaattg aattcggact aaggtttgtg tgaaaaagat
     4501 aaatctttct agagtctaaa gactctgcgt cagatttcct attttcactg taacctttta
     4561 acgtcctcat atcttgtata aacgaggaaa gatgtacgac ttatcccgtg aggtttcatg
     4621 agcgctgaaa gcgtagtaac aacgaatcat gagaagtcag ccgagcccat agtagtgagg
     4681 aaacttctgt agtggaagtg gagcgaaggg gtgaacaact aatcgaagta atcctacttc
     4741 acttgtgtct gtaaaatgag tggtctgata gaactggact ttgac
//
LOCUS       DBERXF010000069         4761 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.69, whole genome shotgun sequence.
ACCESSION   DBERXF010000069 DBERXF010000000
VERSION     DBERXF010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4761
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.69"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            51..1596
                     /locus_tag="ACL8JK_002033"
     rRNA            51..1596
                     /locus_tag="ACL8JK_002033"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1648..1720
                     /locus_tag="ACL8JK_002034"
     tRNA            1648..1720
                     /locus_tag="ACL8JK_002034"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1681..1683,aa:Ala,seq:tgc)
     gene            1845..4746
                     /locus_tag="ACL8JK_002035"
     rRNA            1845..4746
                     /locus_tag="ACL8JK_002035"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1326 a          977 c         1412 g         1046 t
ORIGIN      
        1 gaaaaaaaca ataaatctgt cagtgacaga aatgagtgag aactcaaact tttaatgaga
       61 gtttgatcct ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct
      121 gaaggaggag cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct
      181 gcctggtagc gggggataac tattggaaac gatagctaat accgcataag agtagatgtt
      241 gcatgacatt tgcttaaaag gtgcacttgc atcactacca gatggacctg cgttgtatta
      301 gctagttggt ggggtaacgg ctcaccaagg cgacgataca tagccgacct gagagggtga
      361 tcggccacac tgggactgag acacggccca gactcctacg ggaggcagca gtagggaatc
      421 ttcggcaatg gacggaagtc tgaccgagca acgccgcgtg agtgaagaag gttttcggat
      481 cgtaaagctc tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac actgtgacgg
      541 tatcttacca gaaagggacg gctaactacg tgccagcagc cgcggtaata cgtaggtccc
      601 gagcgttgtc cggatttatt gggcgtaaag cgagcgcagg cggttagata agtctgaagt
      661 taaaggctgt ggcttaacca tagtaggctt tggaaactgt ttaacttgag tgcaagaggg
      721 gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccggtggc
      781 gaaagcggct ctctggcttg taactgacgc tgaggctcga aagcgtgggg agcaaacagg
      841 attagatacc ctggtagtcc acgctgtaaa cgatgagtgc taggtgttag accctttccg
      901 gggtttagtg ccgtagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt
      961 gaaactcaaa ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa
     1021 gcaacgcgaa gaaccttacc aggtcttgac atccctctga ccgctctaga gatagagttt
     1081 tccttcggga cagaggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt
     1141 tgggttaagt cccgcaacga gcgcaacccc tattgttagt tgccatcatt cagttgggca
     1201 ctctagcgag actgccggta ataaaccgga ggaaggtggg gatgacgtca aatcatcatg
     1261 ccccttatga cctgggctac acacgtgcta caatggctgg tacaacgagt cgcaagccgg
     1321 tgacggcaag ctaatctctt aaagccagtc tcagttcgga ttgtaggctg caactcgcct
     1381 acatgaagtc ggaatcgcta gtaatcgcgg atcagcacgc cgcggtgaat acgttcccgg
     1441 gccttgtaca caccgcccgt cacaccacga gagtttgtaa cacccgaagt cggtgaggta
     1501 accgtaagga gccagccgcc taaggtggga tagatgattg gggtgaagtc gtaacaaggt
     1561 agccgtatcg gaaggtgcgg ctggatcacc tcctttctaa ggataaggaa ctgcgcattg
     1621 gtcttgttta gtcttgagag gtcttgtggg gccttagctc agctgggaga gcgcctgctt
     1681 tgcacgcagg aggtcagcgg ttcgatcccg ctaggctcca ttggtgagag atcaccaagt
     1741 aatgcacatt gaaaattgaa tatctatatc aaatagtaac aagaaaataa accgaaaacg
     1801 ctgtagtatt aataagagtt tatgactgaa aggtcagaaa ataaggttaa gttaataagg
     1861 gcgcacggtg gatgccttgg cactaggagc cgacgaagga cgtgacaaac gacgatatgc
     1921 cttgggtagc tgtaagtaag cgatgatcca gggatttccg aatgggggaa cccaacaggt
     1981 aatacctgtt acccacatct gttaaggatg tgaggaggaa gacgcagtga actgaaacat
     2041 ctaagtagct gcaggaagag aaagcaaaag cgattgcctt agtagcggcg agcgaaacgg
     2101 cagaagggca aaccgaagag tttactcttc ggggttgtag gactgcaatg tggactcaaa
     2161 gattatagaa gaatgatttg ggaagatcag ccaaagagag taatagcctc gtatttaaaa
     2221 tagtctttgt acctagcagt atcctgagta cggcgggaca cgtgaaatcc cgtcggaatc
     2281 tgggaggacc atctcccaac cctaaatact ccctagtgac cgatagtgaa ccagtaccgt
     2341 gagggaaagg tgaaaagcac cccgggaggg gagtgaaata gaacctgaaa ccgtgtgcct
     2401 acaacaagtt cgagcccgtt aatgggtgag agcgtgcctt ttgtagaatg aaccggcgag
     2461 ttacgttatg atgcgaggtt aagttgaaga gacggagccg tagggaaacc gagtctgaat
     2521 agggcgcctt agtatcatga cgtagacccg aaaccatgtg acctacccat gagcaggttg
     2581 aaggtgcggt aagacgcact ggaggaccga accagggcac gttgaaaagt gcttggatga
     2641 cttgtgggta gcggagaaat tccaaacgaa cttggagata gctggttctc tccgaaatag
     2701 ctttagggct agcgtcgaca ttagagattc ttggaggtag agcactgttt gggtgagggg
     2761 tccatcccgg attaccaatc tcagataaac tccgaatgcc aatgaattat ggtcggcagt
     2821 cagactgcga gtgctaagat ccgtagtcga aagggaaaca gcccagacca ccagctaagg
     2881 tcccaaaata attgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttag
     2941 cttagaagca gctattcatt caaagagtgc gtaatagctc actagtcgag tgaccctgcg
     3001 ccgaaaatgt accggggcta aaacaattta ccgaagctgt ggataccttt ataggtatgg
     3061 taggagagcg ttctatgtgt gatgaaggta taccgtgagg agtgctggaa cgcatagaag
     3121 tgagaatgcc ggtatgagta gcgaaagaca ggtgagaatc ctgtccaccg taagactaag
     3181 gtttccaggg gaaggctcgt ccgccctggg ttagtcggga cctaaggaga gaccgaaagg
     3241 tgtatccgat ggacaacagg ttgatattcc tgtactagag tatgtagtga tggagggacg
     3301 cagtaggcta actaaagcag acgattggaa gagtctgtct aagcagtgag gtgtgaattg
     3361 agtcaaatgc ttaattctat aacattgagc tgtgatgggg agcgaagttt agtagcgaag
     3421 ttagtgacgt cacactgcca agaaaagctt ctagcgttta aacatactct acccgtaccg
     3481 caaaccgaca caggtagtcg aggcgagtag cctcaggtga gcgagagaac tctcgttaag
     3541 gaactcggca aaatgacccc gtaacttcgg gagaaggggt gctgacttta agtcagccgc
     3601 agtgaatagg cccaagcaac tgtttatcaa aaacacagct ctctgctaaa tcgtaagatg
     3661 atgtataggg ggtgacgcct gcccggtgct ggaaggttaa gaggagtgct tagcgtaagc
     3721 gaaggtatga attgaagccc cagtaaacgg cggccgtaac tataacggtc ctaaggtagc
     3781 gaaattcctt gtcgggtaag ttccgacccg cacgaaaggc gtaatgattt gggcactgtc
     3841 tcaacgagag actcggtgaa attttagtac ctgtgaagat gcaggttacc cgcgacagga
     3901 cggaaagacc ccatggagct ttactgcagt ttgatattga gtgtctgtac cacatgtaca
     3961 ggataggtag gagtctaaga gatcgggacg ccagtttcga aggagacgct gttgggatac
     4021 tacccttgtg ttatggccac tctaacccag ataggtgatc cctatcggag acagtgtctg
     4081 acgggcagtt tgactggggc ggtcgcctcc taaaaggtaa cggaggcgcc caaaggttcc
     4141 ctcagaatgg ttggaaatca ttcgcagagt gtaaaggtat aagggagctt gactgcgaga
     4201 gctacaactc gagcagggac gaaagtcggg cttagtgatc cggtggttcc gtatggaagg
     4261 gccatcgctc aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtt
     4321 cacatcgacg gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg ggctgtagtc
     4381 ggtcccaagg gttgggctgt tcgcccatta aagcggcacg cgagctgggt tcagaacgtc
     4441 gtgagacagt tcggtcccta tccgtcgcgg gcgtaggaaa tttgagagga tctgctccta
     4501 gtacgagagg accagagtgg acttaccgct ggtgtaccag ttgtcttgcc aaaggcatcg
     4561 ctgggtagct atgtagggaa gggataaacg ctgaaagcat ctaagtgtga aacccacctc
     4621 aagatgagat ttcccatgat tatatatcag taagagccct gagagatgat caggtagata
     4681 ggttagaagt ggaagtgtgg cgacacatgt agcggactaa tactaatagc tcgaggactt
     4741 atccaaagta actgagaata t
//
LOCUS       DBERXF010000070         4653 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.70, whole genome shotgun sequence.
ACCESSION   DBERXF010000070 DBERXF010000000
VERSION     DBERXF010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4653
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.70"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..480
                     /locus_tag="ACL8JK_002036"
                     /pseudo
     CDS             1..480
                     /locus_tag="ACL8JK_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558102.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(473..646)
                     /locus_tag="ACL8JK_002037"
     CDS             complement(473..646)
                     /locus_tag="ACL8JK_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HGS1786837.1"
                     /translation="MNIKKRVLSAGLTFASALLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYADNIVN"
     gene            complement(805..2412)
                     /locus_tag="ACL8JK_002038"
     CDS             complement(805..2412)
                     /locus_tag="ACL8JK_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGS1786838.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTAAKEVLEKQVLAPWDAFCVELL"
     gene            2565..4049
                     /locus_tag="ACL8JK_002039"
     CDS             2565..4049
                     /locus_tag="ACL8JK_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGS1786839.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFLNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            4144..4626
                     /locus_tag="ACL8JK_002040"
     CDS             4144..4626
                     /locus_tag="ACL8JK_002040"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGS1786840.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1367 a         1037 c          890 g         1359 t
ORIGIN      
        1 tttaatagtt taaagcacct agcacctgtt tagattgatg aaacaggatt cgatacttat
       61 ttttatcgag aatatggtcg ctcattaaaa ggtcagttaa gaagaggcaa agtatctgga
      121 agaagatatc agaggatttc tttggttgca ggtctaacaa atggtgagtt aatcgctcca
      181 ataacttacg aagagacgat gacgagcgac ttttttgaag cttggtttca gaaatttctc
      241 ttaccaacat taaacacacc atcggttatt attatggata atgcaagatt ccatagaatg
      301 ggtaagttag aactcttgtg tgaagagttt gggtataaac ttttacctct tcctccctac
      361 tcacctgagt acaatcctat tgagaaaaca tgggctcata tcaaaaagca cctcaaaaag
      421 gtattaccaa gttgcaatac cttttatgag gctcttttgt cttgttcttg tttcaattga
      481 ctatattatc agcgtaatag tctaatagat agttaaatgt agttggattt ccactaaagg
      541 ttgatgagta agtttttgta tctgaacctg attggccgca agcagctaaa agcaaagcag
      601 atgcaaaagt caggcctgca ctaaggacac gcttctttat gttcatcttc tttctcctta
      661 atagtgggaa tttgtaaagt taattgaatt tcaagaatga aagtttataa actttggtta
      721 taaaaaacaa aggatttctg tcttttatac agtcctccct tgtttttata cgatttcaat
      781 tttaaatttt tctgcaaaaa atatttatag taattccaca cagaaagcat cccatggagc
      841 caagacctgt ttttcaagta cttctttagc cgcagtgttt tcaatcaaga cagatttgac
      901 ttttccttct actgtcaagt cttgctcttc attggacaag ttagccacaa ctaggaagcg
      961 acggtcgcca tccttacgta tataagcaaa gaccttatca gccgtatcaa gcaattcaaa
     1021 gtcagctcga actagccagc tattctcctt gcgaatttgg accagtttct gataggtata
     1081 gaaaatagaa tctggatttg ccagcgcttc ttggacattg atcatctcgt aatttggatt
     1141 aaccgccaac caaggttgac ctgttgagaa accagcgttt ttgctctcgt cccattgcat
     1201 aggggtacgg gcattgtcac gtccaataac acggatactg tccatgattt cttcaatcgg
     1261 aacacctttt tcaagagcct cacgcgcata gttgagagat tcaatatctt ctacttgatc
     1321 cagtgtttca aacggatagt tggtcatccc aatctcctca ccttggtaga tataaggagt
     1381 tcctctcata agatgaagca agattgcaaa ggctttggca gatttttcgc ggtattcttg
     1441 gtcatttccc cagattgaga cgatacgagg gaggtcatga ttgttccaga agagggaatt
     1501 ccaaccgtcc tcaactccta actctgtctg ccatttgttg aagatttctt ttaacttagc
     1561 gatattcagc tctttttgat agtgccattt aggctgacct tcctgatact gaagaccgat
     1621 atgttcaaac tggaagacca tagacaattc ttgccccttt ggatcagagt aaagcttggc
     1681 aatctctggc gttgctcccc aagtctcccc tactgtcaag agatccttat ctccaaaggt
     1741 cgcctgattc atttccttga gatagggatg gagcatagga ccattattga ctaccttctc
     1801 gtcaggaatt ttgccaatca tgtcaataac atccatacgg aaaccaccaa tacctttatc
     1861 aatccagaag ttcatcatct cataaatttt ctggcgaagt ttttcatttt cccagttgag
     1921 atccggctgt ttcttgctga aaaagtggag atagtattga cctgactttt catcgtattc
     1981 ccaagcagac ccactaaaga tagaatctag gtcattgggt tcatcgcgcc agatatagta
     2041 gtctcgctca gggctgtcag tattttcaca ggcttcgaca aaccaagcat gttcatctga
     2101 ggtatgatta accaccaagt ccatgatgat acgaatgtca cgcttcttag cttctgcaat
     2161 cagctgatcc atgtcctcca tggttccaaa aatagccgca atcgcttgat aatcagcaat
     2221 atcatagcca ttatcatcca tagggctgtc ataaacggga gaaagccaaa ttgctgtgat
     2281 tcctagcttg gctagatagt ccaacttact ggtaatacct ggcaaatcac caactccatc
     2341 tccattacta tccataaaac tctttggata gacttgatag actacggcat tgtgccacca
     2401 tttttcttgc atctgtttac ctcattattt taataatcta tagtatatga tagcactttt
     2461 taaaattttg tgcaagcgtt tgcttaatct ttttaattta ttttttagct ccgtagtttc
     2521 ctaacttcca attttttatt ataatagagt ccagaggtaa aaaaatgaaa aaacaagctt
     2581 ttagttctga acagtatttg aatttacaac gcgaccatat tttggagcgc attaaccaat
     2641 ttgacggcaa gctctactta gagtttggcg gtaaaatgtt agaagatttc cacgctgctc
     2701 gtgtccttcc tggttatgaa cctgacaaca aaatcaagct cttgcaagaa ttgaaagagc
     2761 aggttgaggt tgtgattgcc attaatgcta gcaacattga acattccaaa gcacgtggcg
     2821 acttgggcat ttcttatgac caagaagttc ttcgtttgat tgacaaattc aatgaattag
     2881 ggatttttgt tggttccgtt gtcattacac aatacgctgg ccaacccgct gcagatgcct
     2941 tcctcaacca acttgagaaa aacggaattg attcttatct tcattatcca atcaaaggat
     3001 atccgacgga tatggatcac atcatttccc cagaaggcat gggcaaaaac gactacatca
     3061 aaaccagtcg caacttgatt gtcgtaaccg ctcctggacc cggttctgga aaattggcaa
     3121 cgtgtatgtc caatatgtac cacgaccaaa tcaatggcat aaagtctggc tacgctaaat
     3181 ttgaaacctt ccctgtttgg aatcttcccc ttcatcatcc agttaacttg gcttatgaag
     3241 ctgccacagc tgaccttgat gatgtcaaca tgattgaccc cttccatctt caaacctatg
     3301 gagaaaccac tgtcaactac aaccgtgata tcgaaatctt cccagtgctc aagcgcatgt
     3361 tggaacgtat tctcggaaaa tcaccatacg cttcaccgac agatatgggt gtcaacatgg
     3421 ttggtttcgc tattacagat gacgaggctg ctgtcgaagc ttctaaacaa gaaatcatcc
     3481 gccgttacta tcaaacagtt cttgacttca aagctgaaaa agttggcgaa gctgccgtca
     3541 agaaaattga gttgctcatg aacgacctcg gtatcacacc tgcagaccgt aaggttgctg
     3601 tcgttgcgcg ccaaaaagca gaagaaactg gtggaccagc cctagccttt gaattgccaa
     3661 atggggaaat cgtcactggt aagaactcag aactctttgg ccctacagcc gctgccttga
     3721 tcaacgccat caaaaaatca gctgacatcg ctaaagaagt aaaactaatc gagcctgaag
     3781 ttgttaagcc aatccaaggt cttaaaatcg atcatctcgg tagccgcaat ccacgccttc
     3841 attcaaatga aatcctgatt gcacttgcta tcacagctac agaaaatcct gatgctgccc
     3901 gcgctatgga agaactcggc aacctcaaag gaagcgaagc ccactcaacc atcatcttga
     3961 ctgatgaaga caagaatgtc cttcgtaaac tgggtatcaa cgtaaccttt gacccatact
     4021 accaatacga ccgcttatat cgtaagtaaa gatttcaacc tctctagcct cggagaggtt
     4081 ttctctctgt ctcaggaaca acctttatga tataatgaga gaagaaaact gaaaggattt
     4141 accatgtcaa aagaagttat tgtcgaaagt tttgaacttg accacaccat tgtcaaagca
     4201 ccctatgttc gcttgattgg ggaagaaaca ggaccaaaag gagacatcat ctccaattat
     4261 gatattcgct tggtgcaacc aaacgaagac tctatcccta ctgccggcct tcacactatc
     4321 gagcacctct tagccaaact catccgtacc cgcattgacg gcatgattga ctgttcacca
     4381 tttggttgcc gcacaggctt ccacatgatt atgtggggac gtcacaccag tgctaaaatc
     4441 gcagctgtta tcaaggattc gctcaaggaa atcgctgaaa ctactacttg ggaagatgtc
     4501 ccagggacaa ccatcgaatc ttgcggaaac tacaaggacc acagcctctt ctctgctaaa
     4561 gaatgggcaa aactcatctt ggaacaaggg atttcagatg atgcctttga acgtcatgtg
     4621 atttaaaatc gagtagggga taatctctag ccc
//
LOCUS       DBERXF010000071         4507 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.71, whole genome shotgun sequence.
ACCESSION   DBERXF010000071 DBERXF010000000
VERSION     DBERXF010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4507
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.71"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            714..2060
                     /gene="gdhA"
                     /locus_tag="ACL8JK_002041"
     CDS             714..2060
                     /gene="gdhA"
                     /locus_tag="ACL8JK_002041"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGS1786841.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHGGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVDQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2566..2736)
                     /locus_tag="ACL8JK_002042"
     CDS             complement(2566..2736)
                     /locus_tag="ACL8JK_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786842.1"
                     /translation="MKKENEYVILTIASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2749..3321)
                     /locus_tag="ACL8JK_002043"
                     /pseudo
     CDS             complement(2749..3321)
                     /locus_tag="ACL8JK_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(3344..4149)
                     /locus_tag="ACL8JK_002044"
                     /pseudo
     CDS             complement(3344..4149)
                     /locus_tag="ACL8JK_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
BASE COUNT         1400 a          838 c          739 g         1530 t
ORIGIN      
        1 gccaaatcgt tgtttgatta cagtctatag tgtattgaat ctataacagt acaccttggc
       61 tgctaaaata tttctataaa tcaatttgac tttcctgata gagttgttca catcttattt
      121 caaaccacta taaaagttct ataatctctt tataagattt gcccatcaga cgaaatataa
      181 taaattgaaa ctagaatagt acacctctac ttctaaaaca ttgttagaaa tcgatttgac
      241 tgtcctgatt gatttgtcct attcttgttt cattttacta tagaacgatt tgaaggcgtt
      301 tatgatattt agctgtacta gagtttttta aaagtgtttt gatggtttgg atttcttctt
      361 taattgattt catattacta ttatataatg ctttttgatt ttagtctggt ataaatattg
      421 ctttcctcca aaatggtcat agttttactg gcaaatctaa catatcacgg ataaattaac
      481 aagtgatttc tgaattacta aacattttct tttcttatag cataccatac tttaagattt
      541 tgtctttaag aaagatattt ccaagaaaaa cgttcgtttt tttatctatt ttcaaaaaaa
      601 ccaaaaactg aattgaaaga atttttagaa aatttctgtt ttttctttac agtgaaaaaa
      661 aattctgcta taatgtctta tgtaataaaa tatgacaata aaaggagaac gatatgacat
      721 ctgctaaaga atatatccaa agcgtgtttg aaactgtgaa agctcgtaac gggcacgagg
      781 ctgaattcct ccaagctgtt gaagaatttt tcaacacttt agaacctgta tttgaaaaac
      841 accctgagta tatcgaagaa aatatcttgg cacgtattac tgagcctgag cgcgtggttt
      901 ctttccgtgt tccttgggtt gaccgtgatg gaaaaattca agtaaaccgt ggttaccgtg
      961 ttcaattcaa ctcagctgtt ggaccataca aaggtggact tcgtttccac ccaactgtaa
     1021 accaagggat cttgaaattc ctcggatttg aacaaatctt taaaaatgtc ttgactggac
     1081 ttcctatcgg tggaggtaaa ggtggatcag acttcgatcc taaaggtaaa acagatgctg
     1141 aagtgatgcg cttctgccaa agcttcatga ctgaattgca aaaacacatc ggaccatcac
     1201 ttgacgtacc tgctggtgat atcggtgttg gtggacgtga gattggttac ctttacggtc
     1261 aatacaaacg tcttaaccaa tttgatgctg gtgtcttgac tggtaaacct cttggatttg
     1321 gtggtagctt gattcgtcca gaagcaactg gttacggttt ggtttactat actgaagaaa
     1381 tgctcaaagc taacggtaac agctttgctg gtaagaaagt cgttatttca ggttctggta
     1441 acgttgctca atatgctctt caaaaagcaa ctgaactcgg tgcaactgtt atttctgttt
     1501 ctgactcaaa tggttatgtc atcgatgaaa atggtatcga cttcgatctt ttggttgatg
     1561 ttaaagaaaa acgtcgtgct cgtttgactg agtatgcagc tgaaaaagca actgctactt
     1621 atcatggagg ttctgtatgg acttacgctg gtaactatga tatcgctctt ccatgtgcga
     1681 ctcaaaacga aatcaacggt gaagcagcta aacgtttggt tgatcaaggc gttatctgtg
     1741 tatctgaagg tgccaacatg ccgagcgacc ttgatgccat caaagtttac aaagaaaatg
     1801 gtatcttcta cggacctgcc aaagctgcca acgctggtgg tgtagccgtt tcagcccttg
     1861 aaatgagcca aaatagtctt cgcctctcat ggactcgtga agaagttgat ggccgtctca
     1921 aagacatcat gacaaacatc ttcaacacag ctaaaacgac ttcagaaaca tacggtcttg
     1981 ataaagacta ccttgcagga gcaaacattg ctgcctttga aaatgtagca aatgccatga
     2041 ttgcacaagg tattgtttaa gatttattta ctcaatcctc aatcactacg attggggatt
     2101 tttagcttga attaaaaaat tggaaaatct aattaaataa aatgaaatga aataaaaact
     2161 gaacaaattg attgcggaat tcaaaccaat ttctaacata cttctagaaa ttaatttgac
     2221 ttttctaatc gatttgttca tatcttattt caatttacta tacttactta acccttttta
     2281 tactcaatga aaatcaaaga gcaaactagg aagcgagccg caggctgtac ttgagtacgg
     2341 caaggcaaag ctgacgtggt ttgaagagat tttcaaagag tattaaacaa aaagaaaaac
     2401 cgctactcct aagaatagca atttaatcat gtttttaagc tactactgta gttgctctat
     2461 tatttaagtg ttatgaataa cttcaatatc tttaaagctt tttgttagat ttataatttc
     2521 aactatagcc atctctactc cttagtttac agcaaaaaat tatgcttaat tcttattgtt
     2581 tttgtaaaca atcagcgaac ccaatactat tccattcaac aagcctaaag aaataccata
     2641 ttcaactgga aaatctaaaa aaattgcaaa cactattcca atcatcaccc ctagtgaggc
     2701 tattgttaaa attacatatt cattttcttt cttcattttc tttacacctc atttcctttt
     2761 tgtatataag ctgtagtact ctccaccaag agttattaag tacttatgat ttcctgactc
     2821 aacaatctta ccacctttca ttacaaaaat aatatccgca tccttaatcg ttgacaatct
     2881 atgagctata attatttgag tacaaccctg actttgtata tactttgtta ttctttcctc
     2941 attaatagtg tctaatgcac tagttgcttc atctaaaatt acaatactag gattatttat
     3001 taatgcacgt gccagtgcta tccgttgcct ttgcccacct gaaatatttg accccatctc
     3061 tgagatgata gtattaaatt tcatcggcat agccatgatt tcatcataga tttgaactgc
     3121 tttacaaact tcctctatct tttgtgaagt aacttcgtgc tttaaagtta tattatcaag
     3181 aatacttcgg ttcaataaaa atgaatcctg tggaactact cctaaatttt gacttaatat
     3241 ttttttatct atttgattaa tatttatacc ataaaataaa acttttcctg tatcaatctt
     3301 atataatcct gatggtattt ttgataatag acttcctgca aaactagaat cctagttcat
     3361 gattgataat accaacaatc aaattcatcc gtaatccgaa gcgtttacga tgatttcgat
     3421 aggttgttga aaacatttta agcgttttta ctttggcaaa gatgttctca accttgcttc
     3481 tctccttaga tagcacatgg ttacaggctt tatcttcagc tgttagcggc ttgagtttgc
     3541 tggatttacg tggagtttgt gcttgaagat atatcttcat gagcccttga taaccactgt
     3601 cagccaagat tttaccagct tgtccgatat ttctgcgact cattttgaac aacttcatat
     3661 catgacaata gttcacagcg atatccaaag aaataattct cccttgactt gtgacaatcg
     3721 cttgagtctt catagcgtga aatttctttt taccagaata attcgctaat tcttttttta
     3781 ggtcgattga tttttacttc cgtcgcatca atcattaccg tgtcctcaga actgagagga
     3841 gttcttgaaa tcgcaacacc acctttgaac aagagttact tcaacccatt ggctccgacg
     3901 gattaagttg ctttcgtgaa taccaagatc agccgaaatt tcttcataag ttcgatattc
     3961 tcgcacatat tgaagagtgg ccataagaag gtcttctagg cttaatttag gttttcgccc
     4021 accttttgcg tgtttaagtt gataagctgt ttttaataca gctaacatct cttcaaaagt
     4081 cgtgcgttga acaccaacaa gacgcttaaa tcgtgcatcg gttagttgtt tacttgcttc
     4141 ataattcata gaactattat accatatttt gtttcgcagg aagtctattg aaaaatctcc
     4201 agactagaga actcacggat agttcctaat ctggagattt cttatttgca cttttcttgt
     4261 acaactttag tccacggtaa ataggcctct aaaacctctt tgtttacgag agtttcctcg
     4321 tttggaagac attctagaag ataggataga tatttctcgc tatttatact agactaaaat
     4381 caaaaagcat tatacaatag tgatatgaaa tcaactaaag aagaaatcca aaccatcaaa
     4441 acacttttaa aagactctcg tacagctaaa tatcataaac gccttcaaat cgttctattt
     4501 cgtctga
//
LOCUS       DBERXF010000072         3778 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.72, whole genome shotgun sequence.
ACCESSION   DBERXF010000072 DBERXF010000000
VERSION     DBERXF010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3778
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.72"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            163..816
                     /gene="rr06"
                     /locus_tag="ACL8JK_002045"
     CDS             163..816
                     /gene="rr06"
                     /locus_tag="ACL8JK_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HGS1786843.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            813..2153
                     /gene="hk06"
                     /locus_tag="ACL8JK_002046"
     CDS             813..2153
                     /gene="hk06"
                     /locus_tag="ACL8JK_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HGS1786844.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            2236..2763
                     /locus_tag="ACL8JK_002047"
     CDS             2236..2763
                     /locus_tag="ACL8JK_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HGS1786845.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            2842..>3778
                     /locus_tag="ACL8JK_002048"
     CDS             2842..>3778
                     /locus_tag="ACL8JK_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HGS1786846.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVAVASLFLGGVVHAEGVRSEN
                     TPKVTSSGDEVDEYIKKMLSEIQLDKRKHTHNFALNLKLSRIKTEYLYKLKVNVLEEK
                     SKAELTSKTKKEVDAAFEKFKKDTLKLGEKVAEAQKKVEEAKKKAKDQKEEDHRNYPT
                     NTYKTLDLEIAESDVKVKEAELELLKEEAKTRNEDTINQAKAKVKSEQAEATRLKKIK
                     TDREQAEATRLENIKTDREKAEEVKDKLKRRTKRAVPGEPATPDKKENDAKSSDSSVG
                     EETLPSPSLKSGKKVAEAQKKVAEAEKKAKDQKEED"
BASE COUNT         1321 a          522 c          804 g         1131 t
ORIGIN      
        1 agctgcaaga tgaatgattt tcttgtattg acgttgttgt tgacaaaaag tagcggataa
       61 atgaaatcca ttccattatc atagatgata ggctggtagg aaattttcaa atagcataca
      121 ggaaatagat gtatggagtt ctggtagtag aaagggagag agatgaacat tttagttgca
      181 gatgacgagg aaatgattag agaaggaatt gcagcatttc tgacagaaga gggttatcat
      241 gtcattatgg ctaaggatgg acaagaggtc ttggaaaaat ttcaagatct ccctatccat
      301 ctcatggtac tggatttaat gatgcctagg aagagtggtt ttgaagtgtt aaaagaaatc
      361 aatcaaaagc acgatattcc tgtcatcgtc ttgagtgctc tgggagatga aactactcag
      421 tcacaggtat ttgatctcta tgctgatgat catgtgacaa aacctttttc tttggtactg
      481 cttgtcaagc gtattaaggc gcttatcaga cgttactacg tcatagagga tctttggcga
      541 tatcaggatg taacagtgga ttttacctct tacaaagcac attataaaaa tgaagaaatt
      601 gatctcaaac caaaggaatt actggtacta aagtgtttga ttcagcataa aaatcaagtt
      661 ttaagtagag agcagatatt ggaagaaatt tcaaaagatg tagctgattt accttgtgat
      721 agggtcgttg atgtctatat tcgtactctt cgcaaaaaat tagctttaga ttgtatcgtg
      781 actgtgaaaa atgttgggta taagattagc ttatgataaa aaatcctaaa ttattaacca
      841 agtctttttt aagaagtttt gcaattctag gtggtgttgg tctagtcatt catatagcta
      901 tttatttgac ctttcctttt tattatattc aactggaggg ggaaaagttt aatgagagcg
      961 caagagtgtt tacggagtat ttaaagacta agacatctga tgaaattcca agcttactcc
     1021 agtcttattc aaagtccttg accatatctg ctcaccttaa aagagatatt gtagataagc
     1081 ggctccctct tgtgcatgac ttggatatta aagatggaaa gctatcaaat tatatcgtga
     1141 tgttagatat gtctgttagt acagcagatg gtaaacaggt aaccgtgcaa tttgttcacg
     1201 gggtggatgt ctacaaagaa gcaaagaata ttttgctttt gtatctccca tatacatttt
     1261 tggttacaat tgctttttcc tttgtttttt cttattttta tactaaacgc ttgctcaatc
     1321 ctctttttta catttcagaa gtgactagta aaatgcaaga tttggatgac aatattcgtt
     1381 ttgatgaaag taggaaagat gaagttggtg aagttggtga agttggaaaa cagattaatg
     1441 gtatgtatga gcacttgttg aaggttattc atgagttgga aagtcgtaat gagcaaattg
     1501 taaaattgca aaatcaaaag gtttcctttg tccgcggagc atcacatgag ttgaaaaccc
     1561 ctttagccag tcttagaatt atcctagaga atatgcagca taatattgga gattacaaag
     1621 atcatccaaa atatattgca aagagtataa ataagattga ccagatgagc cacttattgg
     1681 aagaagtact ggagtcttct aaattccaag agtggacaga gtgtcgtgag accttgactg
     1741 ttaagccagt tttagtagat attttatcac gttatcaaga attagctcat tcaataggtg
     1801 ttacaattga aaatcaattg acagatgcta ccagggtcgt catgagtctt agggcattgg
     1861 ataaggtttt gacaaacctg attagtaatg caattaaata ttcagataaa aatgggcgcg
     1921 taatcatatc cgagcaagat ggctatctct ctatcaaaaa tacatgtgcg cctctaagtg
     1981 accaagaact agaacattta tttgatatat tctatcattc tcaaatcgtg acagataagg
     2041 atgaaagttc cggtttgggt ctttacattg tgaataatat tttagaaagc tatcaaatgg
     2101 actatagttt tctcccttat gaacacggta tggaatttaa gattagcttg tagacagatt
     2161 agttttttat taaagttcat atagggttaa cataagtgtg ttattctttg tgtagataaa
     2221 agaaaggata ctaatatggt attagcgatt attttagtaa cattccttat tcgattgatt
     2281 tttttaaagc gttcgataga gaatgagaaa cgaatcctta gcaatggcgg gaaagaattt
     2341 ggagttgaga atacaaaacg attaactatg gctcatattg ttttttatct ctcttgcttg
     2401 gttgaggcaa tggtgcacaa gacaattttt gatggcatgg gcatggttgg tttagtcttg
     2461 cttatttttt ctatgctgat gttgatgttg gtgattcact tgttgggaga tatttggaca
     2521 gtgaagctta tgcttgtcaa taatcacaaa tatgtagatc atatcttgtt taggacagta
     2581 aaacacccta attacttttt aaatatttta cctgagttga ttggcttgac cttgttgagt
     2641 catgcttatg tgacttttgt tttagttttt ccagtttatg cagttatttt gtatcgacga
     2701 atagctgaag aggaaaagct attacatgaa gttataatcc caaatggaag cataaagaga
     2761 taaatacaaa attcgattta tatacagttc atattgaagt gatatagtaa ggttaaagaa
     2821 aaaatataga aggaaataat tatgtttgca tcaaaaagcg aaagaaaagt acattattca
     2881 attcgtaaat ttagtattgg agtagctagt gtagctgttg ctagcttgtt cttaggagga
     2941 gtagtccatg cagaaggggt tagaagtgag aataccccca aggttacatc tagtggggat
     3001 gaagtcgatg aatatataaa aaaaatgttg agtgagatcc aattagataa aagaaaacat
     3061 acccacaatt tcgccttaaa cctaaagttg agcagaatta aaacggagta tttgtataaa
     3121 ttaaaagtta atgttttaga agaaaagtca aaagctgagt tgacgtcaaa aacaaaaaaa
     3181 gaggtagacg cagcttttga gaagtttaaa aaagatacat tgaaactagg agaaaaggta
     3241 gcagaagctc agaagaaggt tgaagaagct aagaaaaaag ccaaggatca aaaagaagaa
     3301 gatcaccgta actacccaac caatacttac aaaacgcttg accttgaaat tgctgagtcc
     3361 gatgtgaaag ttaaagaagc ggagcttgaa ctattgaaag aggaagctaa aactcgaaac
     3421 gaggacacaa ttaaccaagc aaaagcgaaa gttaagagtg aacaagctga ggctacaagg
     3481 ttaaaaaaaa tcaagacaga tcgtgaacaa gctgaggcta caaggttaga aaacatcaag
     3541 acagatcgtg aaaaagcaga agaagttaaa gataaactaa agaggcggac aaaacgagca
     3601 gttcctggag agccagcaac acctgataaa aaagaaaatg atgcgaagtc ttcagattct
     3661 agcgtaggtg aagaaactct tccaagccca tccctgaaat caggaaaaaa ggtagcagaa
     3721 gctcagaaga aggtagcaga agctgagaaa aaagccaagg atcaaaaaga agaagatc
//
LOCUS       DBERXF010000073         3471 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.73, whole genome shotgun sequence.
ACCESSION   DBERXF010000073 DBERXF010000000
VERSION     DBERXF010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3471
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.73"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..300
                     /locus_tag="ACL8JK_002049"
     CDS             <1..300
                     /locus_tag="ACL8JK_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786847.1"
                     /translation="QNRLHNIYKGFTHYKYYRAENSHLIYADYFEMKLKKLLKDDTKV
                     FEKSTFKFVEGYKIYLTESKESGIKQMDNVIKYFEFIESKSIALYFQKRLNELID"
     gene            complement(654..1187)
                     /locus_tag="ACL8JK_002050"
     CDS             complement(654..1187)
                     /locus_tag="ACL8JK_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGS1786848.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1276..2052)
                     /gene="recX"
                     /locus_tag="ACL8JK_002051"
     CDS             complement(1276..2052)
                     /gene="recX"
                     /locus_tag="ACL8JK_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGS1786849.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDINENIVSQVIANLKEEKW
                     INDSQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2090..3457
                     /gene="rlmD"
                     /locus_tag="ACL8JK_002052"
     CDS             2090..3457
                     /gene="rlmD"
                     /locus_tag="ACL8JK_002052"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGS1786850.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYNEAVKALDVNKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDIPYIQSVDMFPHTARTEAVVKLIKK
                     IRKSS"
BASE COUNT         1151 a          590 c          603 g         1127 t
ORIGIN      
        1 caaaataggc tccataatat ctataaggga tttacccact acaaatatta tagagccgaa
       61 aattcacatc taatatatgc agactacttt gaaatgaaat taaaaaaatt attaaaggat
      121 gacacaaaag tttttgaaaa atctacattc aaatttgtag aaggatataa aatatacctg
      181 acagaatcta aagaatctgg aattaaacaa atggacaatg tcataaaata ttttgagttt
      241 attgaatcta aaagtattgc tttatatttt caaaaacgat taaatgagct gatagattaa
      301 atagcatttt ctctgttgag atattgtttt taaaatattg tactaaatga ttgatgctat
      361 gtggaaatac aaaaaaatgt ttttgatacg aagttgacct gtatttttta tactaatcat
      421 tttcgtattt tttgtattaa acgatataag tttgttgtaa acttacaagg aataaagaca
      481 ttaaaaaata acagtatatc tatttgtttt atatatttta cgaattctgc ataaatctct
      541 ttctagtaat gtgttgtaac tctgctataa tagatttatt cctttttgtg tttacacaat
      601 ttattttata ctaccaaaaa aggtcaggat tttgttcctg acctttgaca actttaccga
      661 ttctttagtt ctacatagcg cttgtaccaa atgtttacat aggcttctga gaaaggacca
      721 cgtccattgt taatccaatc aacaagaatt ttgacatgtt cttttaaaat atagtccaag
      781 tcatcagaat aattcatttt gcgtttgtga cgctcgtact cttcaacgtc caagagacgt
      841 ttttccccat ctgtaaaaat tttaacatcc aaatcgtaat caatatactt cagtgcttct
      901 tcatccagat agtaggggct agccatattg caatagtaag aagttccatt atcacgaatc
      961 atggcaatga tattaaacca atatttcttg tgaaagtaaa caatagccgg ttctcgagtg
     1021 acccaacgac gaccatcact ttcggtaaca agtgtatgat cgttgacacc aataatggcg
     1081 ttttctgttg tttttagtac catggtgtcc cgccaagttc ggtggagact cccatcatgc
     1141 ttataacttt gaattgtaat aaagtcgcct tcttttggaa gcttcataac taaccaactt
     1201 tctacaattt ataagtttat catttactat tgtaccataa aattacccaa aatctgtgaa
     1261 tttcacttgg aaatattaaa gatattctct aagagcgctt gctatatccg aaaaatcgta
     1321 gccctttcgt gctaaaactt gagttaaacg ctgcttcagt tcgtatcctt catactttcg
     1381 ggcatactta gtatattgct tatcaagttc cttgaagatg agttcctgag tcgtttcttc
     1441 atcaacttga ctatccaatt cgtcaaaggc aattttagca tcaaaataag agaagccctt
     1501 gttagtcaag ttctggataa tcttatcttg cagggcacga gctggaagtt ttccctcata
     1561 ttttttcaat agtttattgg ctacacgttg agcaacttcc gaaaaatcaa aatcattcaa
     1621 gatttcttct atagtagatt ttgaaattcc tttttgtgct aatttctgag tcagtacata
     1681 aggtcccttg tctcctgaaa gttgattggc attgatgata gcataagcgt actggctatc
     1741 attaatccac ttctcttctt taagattagc aatgacttga gaaacgatgt tttcattaat
     1801 atcatatttt ttcagatatt ctctgacctc tttttcagta cgtgctttaa aggataagtg
     1861 gtagagggcc agattcttac cataagaaaa ttgagcaaag tcttgaatct ctttcaattc
     1921 ctcttcgctt atcaccttat ctctcgataa cataaaacga acaattgtgt cttcggtgat
     1981 atagcatttg tcgccattat caagctccat cagatagagt ctttttttct tttcaagttt
     2041 tgtgattttc atagctctat tataactcaa aatgtgataa gataggggta tgaatctgaa
     2101 agtgaaacaa aaaataccat taaaaatcaa gcgcatggga attaacggtg agggaatcgg
     2161 cttttaccaa aaaacattag tctttgtacc aggagctctc aaaggcgaag atatctattg
     2221 tcagattact tctattagac gcaactttgt tgaagcaaaa ttactgaagg tcaacaagaa
     2281 gtctaaattt cgaattgtgc catcttgtac tatttataat gaatgcggag gctgccaaat
     2341 catgcacctg cattatgata agcagctgga gttcaagacg gacttacttc atcaagcgct
     2401 gaaaaaattt gctcctgcag gatatgaaaa ttatgaaatt cgtccaacta ttggaatgca
     2461 ggaaccaaaa tattacagag ctaagttaca atttcagact cgaaaattta aaaatcaggt
     2521 caaggcgggc ttatatgcac aaaactctca ctatttagta gagttgaaag actgcctggt
     2581 acaagataag gaaacccaag tgattgctaa tcgcttagca gaattactta cttatcacca
     2641 gattccaatc acggatgaga gaaaagttct aggtgtccgt actattatgg tccgacgcgc
     2701 gagaaagacc ggacaggttc agattattat tgttacaaac cgccagctta atttaactca
     2761 attggtaaaa gagttggtta aagatttccc agaagttgtg acagtagctg ttaatacaaa
     2821 tacagctaaa accagtgaga tatatggtga aaagacagag attatctggg ggcaagagag
     2881 tattcaagaa ggtgtactca attatgaatt ttcactatcc cctcgagctt tttatcaact
     2941 aaatcctgaa caaacagaag ttctttataa cgaggcggta aaagccttgg atgttaataa
     3001 agaagaccat ttgattgacg cttattgtgg agttggaacg attggttttg cctttgcaaa
     3061 gaaagttaaa acacttagag gtatggatat tattccagaa gctattgaag atgctaagcg
     3121 aaatgctaaa agaatgggat ttgacaacac acattacgaa gcaggaacag cggaagagat
     3181 tattcctcgc tggtataagg aaggctaccg agcagatgct ctgattgtgg acccaccacg
     3241 tacaggtctg gatgataagt tattagatac tattcttacc tatgtaccag aaaaaatggt
     3301 ctatatttct tgcaatgttt caactttggc aagggatttg gtaaggttag tagaagtcta
     3361 tgatatccct tatattcagt cggtcgatat gtttccacac actgctcgaa ctgaagctgt
     3421 tgtaaaatta attaaaaaaa ttagaaaaag tagttgacaa aacataaaaa g
//
LOCUS       DBERXF010000074         3463 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.74, whole genome shotgun sequence.
ACCESSION   DBERXF010000074 DBERXF010000000
VERSION     DBERXF010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3463
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.74"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..174
                     /locus_tag="ACL8JK_002053"
     CDS             <1..174
                     /locus_tag="ACL8JK_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HGS1786851.1"
                     /translation="WVKDGDTWYYLEASGAMKASQWFKASDKWYYVNGSGALAVNTTV
                     DGYGVNANGEWVN"
     gene            complement(377..1642)
                     /locus_tag="ACL8JK_002054"
     CDS             complement(377..1642)
                     /locus_tag="ACL8JK_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGS1786852.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYQCSKIAVAETSLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSRLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLEGRTQAIIRNHFLRYDRVVRCRVKIITMDMFSPYYD
                     LARQLFPCAKIVLDRFHIIQHLSRAMSRVRVQIMNQLDRKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRIHLTNKEILNKLLSYSEDLKHHYQLYQLYQLLLFHFQNKEPEKF
                     FGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFG
                     FRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            1845..>3463
                     /gene="pspC"
                     /locus_tag="ACL8JK_002055"
     CDS             1845..>3463
                     /gene="pspC"
                     /locus_tag="ACL8JK_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     LPXTG-anchored form"
                     /protein_id="HGS1786853.1"
                     /translation="MFKSNHERRMRYSIRKFSVGVASVAVASLVMGSVVHATENEGTT
                     QAPTSSNRGNESQAEQRRELDLERDKVKKEVREYKEKKVKELYSKSTKSRHKKTVDIV
                     NKLQNINNEYLNKIIQSTSTYEELQKLMMESQSEVDKAVSEFEKDLSSSSSSGSSTEP
                     EASDTAKPNKPTELEKKVAEAQQKVEEAEKKAKDQKEEDHRNYPTITYKTLELEIAEF
                     DVKVKEAELELLKVKAKESRDEKKIKQAEAEVESKQAEATRLKKIKTDRKKAEEEAKL
                     KEAVEKNAATSEQGKPKRRVKRGALGEQATPDKKDYFEKDFRPAFNKNQQMVAIQESL
                     NKLDDETKTVPDGAKLTGEAGNAYNEVRDYAIKVVSENKKLLSQTAVTMDELAMQLTK
                     LNDAMSKLKEAKAKLVPEVKPQPENPEHQKPTTPAPDTKPIPQPEGKKPSVPDINQEK
                     EKAKLAVATYMSKILDDIQKHHLQKEKHRQIVALIKELDEFKKQALSEIDNVNTKVEI
                     ENTVHKIFADMDAVVTKFKKGLTQDTPKEPD"
BASE COUNT         1239 a          572 c          726 g          926 t
ORIGIN      
        1 tgggtgaaag atggagatac ctggtactat cttgaagcat caggtgctat gaaagcaagc
       61 caatggttca aagcatcaga taaatggtac tatgtcaatg gctcaggtgc ccttgcagtc
      121 aacacaactg tagatggcta tggagtcaat gccaatggtg aatgggtaaa ctaaacctaa
      181 tataactagt taatactgac ttcctgtaag aactctttaa agtattccct acaaatacca
      241 tatcctttca gtagataata tacccttgta ggaagtttag attaaaaaat aactctgtaa
      301 tctctagccg gatttatagc gctagagact acggagtttt tttggctctt tgtcaactgt
      361 agtgggttga agtcagctaa gctcgagaaa ggacaaattt tgtcctttct tttttgatat
      421 tcaaagcgat aaaaatccgt tttttgaagt tttcaaagtt tcgaaaacca aaggcattgc
      481 gcttgataag tttgatgaga ttattggtcg cttccagttt ggcattagaa tagtgtagtt
      541 gaagggcgtt gacaatcttt tctttatctt tgaggaaggt tttaaagaca gtctgaaaaa
      601 taggatgaac ctgcttaaga ttgtcctcaa taagcccgaa aaatttctct ggttccttat
      661 tctggaagtg aaaaagcaag agctgataga gctgatagag ctgatagtgg tgtttcaagt
      721 cttccgaata actcaaaagc ttgtttaaaa tctctttatt ggttaaatgt atacgaaaag
      781 taggacgata aaatcgctta tcactcagtt tacggctatc ctgttgaatg agtttccagt
      841 agcgcttgat agccttgtat tcatgagact ttcgatccaa ttgattcatg atttgaacac
      901 gcacacgact catggcacgg ctgagatgtt ggataatatg gaaacgatct agaacgattt
      961 tagcacacgg gaaaagctgt ctagctaagt catagtaagg gctaaacata tccatagtaa
     1021 taattttgac gcgacatcgg acaactctat cgtagcgaag aaagtgattt cgaatgatag
     1081 cttgtgttct tccctcaaga acagtgatga tattgagatt gttaaaatct tgcgcaatga
     1141 agctcatctt tccctttgta aaagcatact catcccaaga cataatctca ggaagacgcg
     1201 aaaaatcatg tttaaagtga aaatcattga gcttacgaat aacagttgaa gttgagatgg
     1261 aaagctgatg ggcaatatca gtcatagaaa tcttttcaat caacttttga gcaatctttt
     1321 ggttgatgat acgagggatt tggtgatttt tcttgacgag ggaagtctca gcgaccgcta
     1381 tttttgagca ctgatagcac ttgaatcgac gctttctaag gagaattcta gtaggcatac
     1441 cagtcgtttc aagataagga attttagaag gtttttgaaa gtcatatttc ttcatttgac
     1501 ttccgcactc agggcaagat ggggcgtcgt agtccagttt ggcgatgatt tccttgtgtg
     1561 tatctttatt gatgatgtct aaaatctgga tattagggtc tttaatgtct agtaattttg
     1621 tgataaaatg taattgttcc atatgattct ttctaatgag ttgttttgtc gcttttcatt
     1681 ataggtcata tgggactttt tttctacaca aaataggctc cataatatcc ataggggatt
     1741 tacccactac aaatattata gagccaaata atgtagcaaa tttcatatac aattcatatt
     1801 agcaggatat actgtagtta attaaaatta tggagaatat agacatgttt aaatcaaatc
     1861 atgagcgaag aatgcgttat tccattcgta aatttagtgt aggagtagct agtgtagctg
     1921 ttgccagtct tgttatggga agtgtggttc atgcgacaga gaacgaggga actacccaag
     1981 cacccacttc ttctaatagg ggaaatgaaa gtcaggcaga acaacgtaga gaactcgatt
     2041 tagaacgaga taaggtaaag aaagaggtca gggaatataa agaaaaaaaa gtgaaagagc
     2101 tctattcaaa atcaactaaa agtcgacata agaagactgt agatatagtt aacaagttgc
     2161 aaaacattaa taacgagtat ttgaataaaa taattcaatc aacctcaaca tacgaagaac
     2221 tacagaaact gatgatggag agtcaatcag aagtagataa agctgtgtct gaatttgaaa
     2281 aggacttatc ttcttcgtca agttcaggct cttccacgga accggaagct tcagatacag
     2341 cgaagccaaa caagccgaca gaactagaaa aaaaggtagc agaagctcag cagaaggttg
     2401 aagaagctga gaaaaaagcc aaggatcaaa aagaagaaga tcaccgtaac tacccaacca
     2461 ttacttacaa aacgcttgaa cttgaaattg ctgagttcga tgtgaaagtt aaagaagcgg
     2521 agcttgaact attaaaagtg aaagctaagg aatctcgaga cgagaaaaaa attaagcaag
     2581 cagaagcgga agttgagagt aaacaagctg aggctacaag gttaaaaaaa atcaagacag
     2641 atcgtaaaaa agcagaagaa gaagctaagt tgaaggaagc tgttgaaaag aatgcagcga
     2701 cttcagagca aggtaaacca aagaggcggg taaaacgagg agctcttgga gagcaagcaa
     2761 cacctgataa aaaagattat tttgaaaaag acttccgtcc agctttcaat aaaaaccagc
     2821 agatggtagc cattcaagaa tccttgaaca aactagatga tgaaacaaaa actgttccag
     2881 atggggctaa actcacagga gaagctggaa atgcctataa tgaggtcaga gattatgcaa
     2941 taaaagttgt ttctgaaaac aagaaacttc tatcacagac agcagtgaca atggatgaac
     3001 tggcaatgca attaaccaaa ttgaacgatg ccatgtctaa attgaaagaa gctaaagcga
     3061 aattggtacc agaggttaaa ccgcagccgg aaaatccaga gcatcaaaaa ccaacaactc
     3121 cagctccgga taccaaacca atccctcaac cagagggtaa gaaaccaagc gtaccagata
     3181 ttaatcagga aaaagaaaaa gctaagcttg ctgtagcaac ctacatgagc aagattttag
     3241 atgatataca aaaacatcat ctgcagaaag aaaaacatcg tcagattgtt gctcttatta
     3301 aggagcttga tgagtttaaa aagcaagctc tttctgaaat tgataatgta aataccaaag
     3361 tagaaattga aaatacagtc cacaagatat ttgcagacat ggatgcagtt gtgactaaat
     3421 tcaaaaaagg cttaactcag gacacaccaa aagaaccaga taa
//
LOCUS       DBERXF010000075         2535 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.75, whole genome shotgun sequence.
ACCESSION   DBERXF010000075 DBERXF010000000
VERSION     DBERXF010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.75"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..559
                     /locus_tag="ACL8JK_002056"
     CDS             <1..559
                     /locus_tag="ACL8JK_002056"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1786854.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYVWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="ACL8JK_002057"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="ACL8JK_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HGS1786855.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1484..2023
                     /locus_tag="ACL8JK_002058"
     CDS             1484..2023
                     /locus_tag="ACL8JK_002058"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1786856.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVATSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQL"
     gene            complement(1977..>2535)
                     /locus_tag="ACL8JK_002059"
     CDS             complement(1977..>2535)
                     /locus_tag="ACL8JK_002059"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS1786857.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIIFKVDLLFQKVSQLFE"
BASE COUNT          866 a          364 c          438 g          867 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagagat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgt
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcgggag ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg ccgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtgattatg gctcttatta tgggaatata cctatgaatt gggttgttat
     1501 aaaaataaaa gatatttttt caatgaatac aggtctttct tacaagaagg gcgatttaag
     1561 cattaataat aaaggtgtta gaattatacg tggtggtaat attaagcctt tagaattttc
     1621 tctgttggat aatgattact acattgatac acaattcatc tcctctgagc aagtttattt
     1681 aaaacataat cagctaataa cacctgtagc aacctcttta gaacatattg gaaagtttgc
     1741 aagaatcgat aaagactatg atggtgttgt ggctggtgga tttattttcc aattaacacc
     1801 attcgaaagt tcagagatta tttcaaaatt tctattattt aacttgtcct ctccgttatt
     1861 ttataaacaa ttgaaagcaa taactaaact atcaggtcaa gctttatata atattcctaa
     1921 aactacactg agcgagctat taattccgtt agctcctttt gaggaacagg aacttattac
     1981 tcaaaaagtt gagaaacttt ttgaaaaagt aaatcaactt tgaaaatgat tcttttcatc
     2041 tcttcatgat tagaaatagg gattaataat tcggagatac tggtactatt taatgttttc
     2101 cctttgatag catcttttga atcacctaaa gtagagataa gtggcaaaaa tatcattaag
     2161 taatctctga taatattttc tttattagca taggggaata tcgatataat ggcttcatta
     2221 tgagtggcag gaatatccaa tatggcaact tttccaatag ataatttaaa actcattaat
     2281 aaagttcctt taggtgaaat gtctattttc tttgatttta atgctaattt agaaatagat
     2341 tctctcgtat tagttacata accagatata ggcatatctg atatagatac ccaaggtatt
     2401 tcagttcccc aaaaagtagc ttcactgcgt ggaggagttt ttcctattct gaagttaact
     2461 aggctagcaa atttaatata tctccatgct tctgggattt catatatagg ataagaggtt
     2521 gtttcgtctt tgttc
//
LOCUS       DBERXF010000076         2233 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.76, whole genome shotgun sequence.
ACCESSION   DBERXF010000076 DBERXF010000000
VERSION     DBERXF010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2233
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.76"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            30..155
                     /locus_tag="ACL8JK_002060"
                     /pseudo
     CDS             30..155
                     /locus_tag="ACL8JK_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812181.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(127..1602)
                     /locus_tag="ACL8JK_002061"
     CDS             complement(127..1602)
                     /locus_tag="ACL8JK_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGS1786858.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSILLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT          660 a          487 c          410 g          676 t
ORIGIN      
        1 ttgaggcagg atttgataag ctgatagaaa ttaagcgatt gaccgcttct aattcaaggg
       61 ctttttgccg tgctctaaaa tcatcgccaa atcatcaaat tgaaataaga aatagtttag
      121 ataaaactat tgacttttct tatagtttgt ctttctctta ataacgttga tatgattgac
      181 ctctggatct tccgtccctt ggagggagca accacgttcc ttggcgaatt ggatatagtc
      241 gacaatttct cgtgtaatgc gttcaccagg agccaagata ggaatacctg gagggtaaca
      301 cataacaaat tctccacaga cctgtccaac agaatcatcc aaagttaaac tttttctttc
      361 tgaatagaag gcttcttgcg gagacagcac taactcgggc tgaatatatt ctcctgctat
      421 caaatctttt ccatctcttg aatagagtct cttaatatca gccagagcac caaccaagcg
      481 ctcgatgtct tggatgcggt cgccgatgga aatataggcc aagatattgc cgatatcacc
      541 aaactcgatc tgaatgtcgt attcgtctcg caagaggtca taaacctcga tacctgttaa
      601 gccaataccc tgagtgtaaa ctgacagctt agttacgtca aaatcgcaaa ccgaaacacc
      661 gtctattaac tcttttgagt aggcatagta gccaccgata gcattgattt cacggcgggc
      721 atactcagat agctcaatga ctttctcaaa cgactcttta ccacgaaggg ccaagttgcg
      781 acgtgaaata tccaaactag ccatcaacaa gtaagaggca gatgtagact gggtcaggtt
      841 aattatctga cgaacgtatt cagaattcat ctgctccccg ataagtaaaa tggagctttg
      901 ggtcaaactc ccaccagact tatgcatgga aactgctgcc atatcagccc ctgcatccat
      961 agcagaaatt ggaagtttat cagtgaaatg caaatgcgct ccgtgggctt catctactaa
     1021 aaccatcatg ccagcttcat gagccatttc tgtcaacccc tttaggtctg aacagatgcc
     1081 gtagtaagta ggattgttga ttaggatagc cttagcatct ggatggtcct ttatggcctg
     1141 tgctactcgg tcattttcaa gacctaaagc gataccaatc ttaggatcta cactcatctc
     1201 gatatagatg ggaatggcac cacatagaac caacgcattg atagcagatt tatggacatt
     1261 tcgtggcaga ataatcttat ctcctgcctt gcaggttgcc agaatcatag tctgcaccga
     1321 tgaagttgtt ccaccaatca ttagaaaggc atggctagct ccaaaagcat ctgcagccag
     1381 ctcctctgca tcacgaataa tcgaaatagg atggcctaaa ttatccaagg gtttcatcga
     1441 attgacatca atgcctacac atttttctcc taagagttcg acaagttctg gatttccccg
     1501 tccacgcttg tgacctggaa catcaaaggg aacaatcctt ttcttgcgta acttcaccaa
     1561 ggcctcataa attggggctt ggttttgatc taactctttc aaaacatact cctttcaata
     1621 tttttaggac cttatgaaaa ctaaggaact aaaggttgac tcatgaaaaa agagcaggtt
     1681 ttcacctgct ctgcaatctt ctgacgtgtt tattttggtt tctgttgagt atgtctgttc
     1741 ccgatgtttc ctaactctct agtagcaaat attacgtact ttattgatcg tttcacaaga
     1801 tgacgtgtgc tttcaccaca ctaaaaattt atgaattaga acaagtgtcc taacatcaac
     1861 ttataaaagt aggcttttaa ccctatcaat aatgtggctt ttcaaccacg cttcggcatt
     1921 caaccctgcc tgtccgtagg cattttttac tcgggtttat atttgctaga aaacatcatc
     1981 tcattttcta agctttatta ctatatcatg tttttaagaa cttgtaaagt attttttgat
     2041 aaaaaataaa aatatagtag attgaaacta gaatagtaca cctctgcttc taaaacattg
     2101 ttagaaatag attttactgt cctgatcgat ttgttctgtt cttgtttcat tttactatat
     2161 gttcgtaaat gaaagttcta taatgaagtt agccacccag ccctcctaaa aattagatgg
     2221 ttcaactaac cga
//
LOCUS       DBERXF010000077         2112 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.77, whole genome shotgun sequence.
ACCESSION   DBERXF010000077 DBERXF010000000
VERSION     DBERXF010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2112
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.77"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(117..578)
                     /locus_tag="ACL8JK_002062"
     CDS             complement(117..578)
                     /locus_tag="ACL8JK_002062"
                     /inference="COORDINATES: protein motif:HMM:NF013842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGS1786859.1"
                     /translation="MGKERREQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(545..688)
                     /locus_tag="ACL8JK_002063"
     CDS             complement(545..688)
                     /locus_tag="ACL8JK_002063"
                     /inference="COORDINATES: protein motif:HMM:NF013842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGS1786860.1"
                     /translation="MAYSTDFKQGALDSIKGGHRHVEAAKVFDVGVRTLFTWEKKDVS
                     KGT"
     gene            956..1336
                     /locus_tag="ACL8JK_002064"
     CDS             956..1336
                     /locus_tag="ACL8JK_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGS1786861.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            1436..1657
                     /locus_tag="ACL8JK_002065"
     CDS             1436..1657
                     /locus_tag="ACL8JK_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGS1786862.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            1674..1988
                     /gene="trxA"
                     /locus_tag="ACL8JK_002066"
     CDS             1674..1988
                     /gene="trxA"
                     /locus_tag="ACL8JK_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGS1786863.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
BASE COUNT          675 a          418 c          384 g          635 t
ORIGIN      
        1 ttttgtatat atatatatat atatattata agataagttt tttataaaga cacgcaaatg
       61 agtataaatc agctaatttt tggtttacat tcctattttt atgcataatt attctgtcat
      121 tctctaattt gtgaatcaat atatctgatt agaaaactac cattgagttt ttgctccacc
      181 tcattagtcc gctcaaaacg ccgtccgcta atcttgtcat agactttctc ccctctagga
      241 gcccctgcat aaggacgata gaggtagcgg ttgattcccg tttcgtcaat atataggact
      301 ggtaaatctt ttaggttatc caaaatatca agaaactcag aaactttctc aggcttttgt
      361 tccctaaaac tggtcgtctt ttttaaaatg accttaatct gctttaaaac tgcccatacg
      421 gagggcaaag cacaatcaaa acgggccgca atttcccgta aaaaagcgtc tggatgagcc
      481 tctacaaagg ctttcaattc ttctaaaggg atcttacgct ttttgacgac tcgctttttc
      541 cgctctaagt tcccttgctc acgtctttct tttcccacgt gaagagagtt ctgacgccga
      601 catcaaaaac tttggccgcc tcgacatgtc tgtgccctcc tttgatggaa tctaatgctc
      661 cttgtttaaa atcagtacta tatgccatag ctttattaga ccatgcttat tttaaactaa
      721 gcaactatag atagagaaat gaaataaaat ctgaattcga atgtgataag gagttagaaa
      781 ttgaaacaat aggattcccc cattattcac acaaaataaa accactaaaa aacagagctt
      841 gccagcattc ttgaaaagta gtataattat tgcatgcgca atcatcttgt gacgcagaga
      901 ctgcccgtta atggactttc ttctatatta tgactctaaa aagaaaggag acactatgac
      961 ctatttggaa aaatggtttg acttcaatcg gcgtcagaaa gaaattgaaa gtctcttgga
     1021 agagaccatt gcccaacaga gcgagcaaag tctgaccttg aaagagttct acctgctcta
     1081 ctatctggac ttggctgaag aaaaatctct acgccagatt gacctgccag ataagcttca
     1141 tctgagcccg agcgcagttt ctaggatggt ggctcgcttg gaagctaaaa attgcggtct
     1201 actcagtcgc atgtgttgcc atcaagatag acgctctagt tttatctgcc tgacaaatga
     1261 tgggcaaaag acactggcct cgctacaaaa aactgtcgaa gaaagcttgg aagcaggttt
     1321 ggatttcttg atttaagatg atttttaaaa aaagttgcgt gcgcaatcat ttttcttgac
     1381 attctctttt ataaggagta aaataaagtt agcattaaac aaaggagttt taaatatgat
     1441 tgaaattacc tatatagatg ccagcaagaa cgaaagaact gtgactttcg agtcttatga
     1501 agactttgaa cgttcgcaac aagcttgcct tatcggcgtc gcagactact accctgtcca
     1561 aaaattaact tacaagggtc ataatttgga ctaccatggg acttatggag atatcttctt
     1621 ctatctcatg aaacaagatt taagccaata taactaaaaa aaggagaaat acaatggcaa
     1681 aagcaattac agatgcaaca ttcgaacaag aaacaaaaga tggtttggtc ttagtagact
     1741 tctgggcaac ttggtgtggt ccatgtcgta tgcaaggtcc aatcttggac aaattgtctg
     1801 aagaactttc agaagatgtc ttgaaaatcg ttaaaatgga cgttgatgaa aatccaaaca
     1861 cagctcgtgc ttttggaatc atgtctattc caactcttct cttcaaaaaa gacggccaag
     1921 ttgtcaaaca agttgcaggt gttcacacag cagaacaaat caaggccatc attgctgaat
     1981 tgagctaatc aaacgagaga ccaagtactt tctttggtct cttttttctt gccctttgcc
     2041 atttttcaaa aaatatgcta gactatagta gattgaaact agaatagtac acctctactt
     2101 ctaaaacatt gt
//
LOCUS       DBERXF010000078         1854 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.78, whole genome shotgun sequence.
ACCESSION   DBERXF010000078 DBERXF010000000
VERSION     DBERXF010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1854
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.78"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..1754)
                     /locus_tag="ACL8JK_002067"
     CDS             complement(<1..1754)
                     /locus_tag="ACL8JK_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_142291904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HGS1786864.1"
                     /translation="MFFRRQKGEYRETDRVTRFKLIKSGKHWLRASTSLFGLFKVMRG
                     GVDTTQVMTETVEDKVSHSITGLDILKGIVAAGAVISGTVATQTKVFTNESAVLEKTV
                     EKTDALATNDTVVLGTISTSNSASSTSLSASESASTSASESASTSASTSASTSASESA
                     STSASISISASSTVVGSQTAAATEATAKKVEEDRKKPASDYVASVTNVNLQSYAKRRK
                     RSVDSIEQLLASIKAAVFSGNTTVNGAPAINASLNIAKSETKVYTGKGVDSVYHVPIY
                     YELTVINDGSKLTFTYTVTYVNPTTKTLGNISNMSNGYSIYNSGTSIQTMLTLGSDLG
                     IPSGVKNSITDKNGRQVRSYNTSTMTTQGSGYTWGNGAQMNGFFAKQGYGLTSSWTVP
                     INGTDTSFTFTPYAARTDRIGINYFNGGGKVVESSTTSQSLSQSKSLSVSASQSASAS
                     ASTSASASASTSASASASTSASESASTSASASASTSASASASTSASSSASTSASASAS
                     TSASASASTSASSSASTSASASASTSASVSASTSASASASTSASVSASTSASASASTS
                     ASESASTSASASASTSAS"
BASE COUNT          490 a          397 c          410 g          557 t
ORIGIN      
        1 tcagatgctg aggtacttgc tgaagctgag gcactggttg atgcggattc agacgcgctg
       61 gtgcttgctg aggccgacgc actggtgctt gctgagactg atgcactcgt tgatgctgaa
      121 gccgaggcgc tggtgcttgc tgagactgat gcactcgttg atgctgaagc cgaggcgctg
      181 gtgcttgctg aagacgacgc actggtactt gctgaagctg acgcactggt tgacgctgaa
      241 gctgaggcac tggttgatgc tgaagacgac gcactcgttg atgctgaagc cgacgcactc
      301 gttgatgctg aggctgaggc agacgttgat gcggattcag acgcacttgt tgatgctgaa
      361 gctgaggcac tcgttgatgc tgaagccgac gcacttgttg atgctgaagc tgaggcgctt
      421 tgactagcac ttactgagag tgacttagac tgtgaaagtg actgactggt cgtgctagat
      481 tcaactacct ttcctccacc attgaagtag ttaattccaa ttctatctgt tctagcagcg
      541 taaggggtaa atgtaaagga tgtatccgtt ccattaattg gtacagtcca agatgatgtt
      601 aatccatatc cttgcttagc aaagaaacca ttcatttggg caccatttcc ccaagtatac
      661 ccactaccct gcgtcgtcat tgtagatgta ttataggatc gaacctgtct accatttttg
      721 tcagtaatgg agttctttac acctgaaggg ataccaagat cactgccaag ggttaacatt
      781 gtttgtattg aagtacctga attatagata gaatatccat tactcatatt tgatatatta
      841 ccaagagtct ttgttgtagg attcacatac gtaaccgtat aggtaaaggt caattttgaa
      901 ccatcattta tcactgtcaa ttcatagtaa attggaacat gatataccga atctacacct
      961 ttacctgtat aaacttttgt ctcactttta gcaatgttta gacttgcatt aattgcaggg
     1021 gcgccattta cagtcgtatt gccagaaaaa acagcagctt ttatagaagc cagcaattgc
     1081 tcgatggaat ccactgaacg cttgcgtcgc ttagcataag attggagatt gacatttgta
     1141 actgatgcta cataatcact agctggtttc ttacgatctt cttcgacctt cttagcagtt
     1201 gcttctgtag cggcagctgt ttgtgatcct accacagtag atgatgcaga gatacttatc
     1261 gaagccgatg tacttgctga ttctgatgca cttgtactcg ctgaggtcga agcgctggtt
     1321 gaggctgact cagatgcaga tgtacttgcc gactctgaag ctgacaaact agttgaactc
     1381 gctgaattac ttgtagatat cgtacctaga actactgtat catttgttgc caaagcatcc
     1441 gttttctcta cagttttttc aagtactgcc gactcatttg taaatacctt cgtttgagtt
     1501 gcaacggttc cacttatgac agctcccgca gcaactatcc ccttgaggat atcaagccca
     1561 gtaattgaat gacttacttt atcttctacc gtttcggtca tgacctgagt agtatcaaca
     1621 ccaccacgca tgaccttaaa caagccaaaa agagaagtcg aggcccgtag ccaatgcttc
     1681 cctgatttga ttaatttgaa ccgagttact cggtctgttt ctctatattc acccttctga
     1741 cgtctaaaaa atattttgaa atttcctttc gagtattatt ttcatgtatg gatataaata
     1801 aattaccata ctataattat agaataggga acccaaaata gcaagaaact tgag
//
LOCUS       DBERXF010000079         1280 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.79, whole genome shotgun sequence.
ACCESSION   DBERXF010000079 DBERXF010000000
VERSION     DBERXF010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1280
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.79"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>1280
                     /locus_tag="ACL8JK_002068"
     CDS             <1..>1280
                     /locus_tag="ACL8JK_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGS1786865.1"
                     /translation="VPDSRPEEPSPQLTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAV
                     RKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGTKKTDLPSSDRE
                     FYNKAYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVEDILAFLAPIR
                     HPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSH
                     WIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLD
                     RMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVE
                     HPNERPHSDNGFGNASDHVRKNKADQDSKPDEDKEHDEVSEPTHPESDEKENHAGLNP
                     SADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSV"
BASE COUNT          435 a          262 c          278 g          305 t
ORIGIN      
        1 gtaccagatt caagaccaga agaaccaagt ccacaactga ctccagaacc tagtccaagt
       61 ccgcaacctg caccaaatcc tcaaccagct ccaagcaatc caattgatga gaaattggtc
      121 aaagaagctg ttcgaaaagt aggcgatggt tatgtctttg aggagaatgg agtttctcgt
      181 tatatcccag ccaaggatct ttcagcagaa acagcagcag gcattgatag caaactggcc
      241 aagcaggaaa gtttatctca taagctagga actaagaaaa ctgacctccc atctagtgat
      301 cgagaatttt acaataaggc ttatgactta ctagcaagaa ttcaccaaga tttacttgat
      361 aataaaggtc gacaagttga ttttgaggct ttggataacc tgttggaacg actcaaggat
      421 gtctcaagtg ataaagtcaa gttagtggaa gatattcttg ccttcttagc tccgattcgt
      481 catccagaac gtttaggaaa accaaatgcg caaattacct acactgatga tgagattcaa
      541 gtagccaagt tggcaggcaa gtacacaaca gaagacggtt atatctttga tcctcgtgat
      601 ataaccagtg atgaggggga tgcctatgta actccacata tgacccatag ccactggatt
      661 aaaaaagata gtttgtctga agctgagaga gcggcagccc aggcttatgc taaagagaaa
      721 ggtttgaccc ctccttcgac agaccatcag gattcaggaa atactgaggc aaaaggagca
      781 gaagctatct acaaccgcgt gaaagcagct aagaaggtgc cacttgatcg tatgccttac
      841 aatcttcaat atactgtaga agtcaaaaac ggtagtttaa tcatacctca ttatgaccat
      901 taccataaca tcaaatttga gtggtttgac gaaggccttt atgaggcacc taaggggtat
      961 actcttgagg atcttttggc gactgtcaag tactatgtcg aacatccaaa cgaacgtccg
     1021 cattcagata atggttttgg taacgctagc gaccatgttc gtaaaaataa ggcagaccaa
     1081 gacagtaaac ctgatgaaga taaggaacat gatgaagtaa gtgagccaac tcaccctgaa
     1141 tctgatgaaa aagagaatca cgctggttta aatccttcag cagataatct ttataaacca
     1201 agcactgata cggaagagac agaggaagaa gctgaagata ccacagatga ggctgaaatt
     1261 cctcaagtag agcattctgt
//
LOCUS       DBERXF010000080         1247 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.80, whole genome shotgun sequence.
ACCESSION   DBERXF010000080 DBERXF010000000
VERSION     DBERXF010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1247
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.80"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            236..676
                     /locus_tag="ACL8JK_002069"
     CDS             236..676
                     /locus_tag="ACL8JK_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS1786866.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            673..1131
                     /locus_tag="ACL8JK_002070"
     CDS             673..1131
                     /locus_tag="ACL8JK_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HGS1786867.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
BASE COUNT          397 a          280 c          238 g          332 t
ORIGIN      
        1 ccttgccaga gggagtaaaa tagtggtata ctcaataaaa atcaaagagc aaactagaaa
       61 gctaggcgca gacagctcaa aacactgttt tgaggttgta gataaaactg acaaagtcaa
      121 caactatcct acggcaagac gacgctgacg tggtttgaag agatttttga agagtattaa
      181 taaaggtgta caagaagtga gattaatttt gtatgaaaaa caaggagaga aatttatgaa
      241 agtagaatta cagattagtg agacttacga ggaggaaaag ctgattgtcc aagcacctca
      301 gccgacagat aaagttcaga aagtcatcga gttcgcagaa aatctggacc aaagagaaaa
      361 aatcaaaggg aaaatcgatg atcaggtcta tctagttgag attggcaaga ttcagcgctt
      421 ctatatcgag aatcggaagg ttctagcaga aaccgcgagt cagacctaca gcattgattt
      481 gcgactctat caggttctta aactcttgcc aaccaatttt atccaaattt cccaatcaga
      541 aatcatcaat atcgattcca tctctcacct caagctcacg ccaaacggtc tggtagaaat
      601 tttcttgaaa aacgaaagct tcacctactc ttcacgccgt tatctaaaaa ccatcaagga
      661 gaaattagaa ctatgaaaaa acaagtattt cacgatgcag ctgccggtgt tcttatcggc
      721 ctcatcctct ccatcctctt ttcactcatt tatgcaccaa atacctacgc accactaaat
      781 ccctactctc tcatcggcca agtgatggat cagcatcagg ttcacggtgc cctggtcttg
      841 ctctactgca cacttatctg ggcagccatc ggtatgctct tcaactttgg caaccgctta
      901 ttcagccgtg actggagcat gcttcgtgcc actctgactc atttcttcct tatgctggct
      961 ggctttgtcc cactagcaac tcttgctggt tggttcccct tccactggat tttctacctc
     1021 cagctcatta tcgagtttgc gattgtctat ctcatcatct gggctattct ctataaaaga
     1081 gaggctaaaa aagtagatca catcaatcaa ctcttggagc atagaaaata ggaacctcat
     1141 aataagcaaa tccgagaaag aaacttctcg gtttttcttt atcctgctgc accttactat
     1201 agtgaaatga aataagaaca ggataaatcg atcaggacag tcaaatc
//
LOCUS       DBERXF010000081         1202 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.81, whole genome shotgun sequence.
ACCESSION   DBERXF010000081 DBERXF010000000
VERSION     DBERXF010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1202
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.81"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..375)
                     /locus_tag="ACL8JK_002071"
     CDS             complement(<1..375)
                     /locus_tag="ACL8JK_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS1786868.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPDKKQASTNFKPAGQSIEQR"
     gene            complement(796..1194)
                     /locus_tag="ACL8JK_002072"
     CDS             complement(796..1194)
                     /locus_tag="ACL8JK_002072"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS1786869.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          322 a          233 c          206 g          441 t
ORIGIN      
        1 ccgctgttcg atggattgac cagcaggttt aaagttggtg ctagcctgtt tcttatcagg
       61 cgaaaatttt tggttatgat agtggagaat cttttccttt agttccttgg tcaagcttga
      121 tttcttgacc gagcgcttgc gattgttttc ataagactgt tgagcatagt cggcagaata
      181 aacttctttg aagcgccctt ttccaagaca ttgtcggact gtcccgcgct tgatttcagt
      241 gtggatagtt tgaggagctt ttccaagtag agaggcaatt tctctatttg atttcccttc
      301 ttttttccat ctttcgatta agcgacggct atcgattgtc aaatgtttgg cttttgtagt
      361 ataattgtct tgcatctctg tgcctttctt gtgtttgtgg ttgaacaaca agtataatac
      421 agaggtgttt tcttatgcct acaagagctt tcattatttc cattttcttt tggatttcac
      481 tctattctga aaaacttgtg tatatttact gaaactagca agtcttacct gtaaatttaa
      541 tgaaagcaac acaaaatccg agaggggaat ctcggattaa tgtcaattta aaaagataga
      601 gagtttttag tttaaataaa ttgttttaaa atatcaacaa catcacttct tttcttaacc
      661 tgataagcct taattcctaa ttttggggct acgattatat tgtcctcaat atcgtctaga
      721 aagacacaat ttctaggtta taactggtat ttatcgatag ttactcatat atatcagtcc
      781 acttccatac tcaccttaca gattcttttg gtaataatat ctttgcctaa tgtagagata
      841 atcttgcaaa gaaaaaactt ccttgtagcc atgtttctga taaaagtccg gtgcctggaa
      901 ctggtaagta ttgacaaagg caaaacaaca atttcgattc ttagcttcac tttctgcctg
      961 ttgcaatagt tttgaaccga ttccttgccc tcgcagttcc tcttttacaa acaaatactc
     1021 gatttctagc caatttccaa aagtctctgc tatcaaacct gccaggagat tgcccttttc
     1081 atcttcgaca taaagattaa gtggctcact ttcagcctct tctctttttg aacggttata
     1141 aacacgaatc agattcccta tttcttgcga tttatgtgat tccttatttt ccaatctaaa
     1201 gt
//
LOCUS       DBERXF010000082         1157 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.82, whole genome shotgun sequence.
ACCESSION   DBERXF010000082 DBERXF010000000
VERSION     DBERXF010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1157
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.82"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            126..>1157
                     /locus_tag="ACL8JK_002073"
     CDS             126..>1157
                     /locus_tag="ACL8JK_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGS1786870.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QAAQKTENLTPDEVSKKEGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDATHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELE"
BASE COUNT          411 a          221 c          226 g          299 t
ORIGIN      
        1 atttttatta tgtatatatg taaaattctt gacaagcaat attaaaaaga gtaaactatt
       61 aactagttaa ttaactggtt tattacttta tagtgaatca aatatactta agaaaagagg
      121 aaagaatgaa aatcaataaa aaatatctag ctgggtcagt agctacactt gttttaagtg
      181 tctgtgctta tgaactaggt ttgcatcaag ctcaaactgt aaaagaaaat aatcgtgttt
      241 cctatataga tggtaaacaa gcagcacaaa aaacggagaa tctgactcct gatgaggtca
      301 gtaaaaaaga aggtatcaat gccgaacaaa tcgtcatcaa gataacagac caaggctatg
      361 tcacttcaca tggggaccac tatcattatt acaatgggaa ggttccttat gacgctatca
      421 tcagtgaaga attgctgatg aaggatccaa actaccagct aaaggacgag gatattatca
      481 gtgaaatcaa gggtggttat gttatcaagg tagatggaaa atactatgtt taccttaagg
      541 atgcaactca tgcggataat gtccgtacaa aagaagaaat caatcgacaa aaacaagaac
      601 atagtcagca tcgtgaagga gggacttcag caaacgatgg tgcggtagcc tttgcacgtt
      661 cacagggacg ctacaccaca gatgatggtt atatctttaa tgcttctgat atcattgagg
      721 acacgggtga tgcttatatc gttcctcacg gcgaccatta ccattacatt cctaagaatg
      781 agttatcagc tagcgagtta gctgctgcag aagccttcct atctggtcgg ggaaatctgt
      841 caaattcaag aacctatcgc cgacaaaata gcgataacac ttcaagaaca aactgggtac
      901 cttctgtaag caatccagga actacaaata ctaacacaag caacaacagc aacactaaca
      961 gtcaagcaag tcaaagtaat gacattgata gtctcttgaa acagctctac aaactgcctt
     1021 tgagtcaacg ccatgtagaa tctgatggcc ttgttttcga cccagcgcaa atcacaagtc
     1081 gaacagccag aggtgtagct gtccctcatg gtaaccatta ccactttatc ccttatgaac
     1141 aaatgtctga attggaa
//
LOCUS       DBERXF010000083          845 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.83, whole genome shotgun sequence.
ACCESSION   DBERXF010000083 DBERXF010000000
VERSION     DBERXF010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..845
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.83"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(43..234)
                     /locus_tag="ACL8JK_002074"
     CDS             complement(43..234)
                     /locus_tag="ACL8JK_002074"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS1786871.1"
                     /translation="MKTKEQTRKLAAGCSKHCFEVMDRTDVVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFEEIFKEY"
     gene            248..610
                     /locus_tag="ACL8JK_002075"
     CDS             248..610
                     /locus_tag="ACL8JK_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HGS1786872.1"
                     /translation="MLEVGLNSLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT          269 a          127 c          153 g          296 t
ORIGIN      
        1 cgaaatctag tggaatgaat ctggaatagt ccatcgagct ttctaatact ctttgaaaat
       61 ctcttcaaac cacgtcaacg tcgccttgcc gtgtgtatgg ttactgactt cgtcagttct
      121 atccacaacc tcaaaacagt gttttgagct gactacgtca gttctatcca taacttcaaa
      181 acagtgtttt gagcaacctg cggctagttt cctagtctgc tctttggttt tcattgagta
      241 taacacattg ttagaagttg gtttaaattc cctaatcagt ttgttcacat ttaccttcga
      301 tatattatat cccatagtta aggttggtca tacagatgat tatagtcatg gagccgtaaa
      361 acttagtgtt tctttagttg acaaagatgc catgaaaaaa atatctgtaa ctgtaatagg
      421 atattttgaa ataaatatag atgaaaatat caccgatatt ctatacgtaa atggtactgc
      481 tattctttat cattatttac gttctattgt ttcaatagtt tcggcaattg atagcagtga
      541 agcaatgttg ctacctacca ttaatgtttt agagttacta gataaatctc aaccttttga
      601 agaagaataa tttattagct cactaaattg agggtaagga aaagtaaaat cagtaagaaa
      661 aatgtcttgc attatacagc aaccttttgg gaatgagtag atggattgaa taaaatttta
      721 ttaagagtgg atgatttatc tgtagattat tattggacag ttagtcttga agtagtctaa
      781 gaattaggtt ataatcagta gaatccttgc taataatgag gaggttagtt tatgtatagt
      841 agact
//
LOCUS       DBERXF010000084          829 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.84, whole genome shotgun sequence.
ACCESSION   DBERXF010000084 DBERXF010000000
VERSION     DBERXF010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..829
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.84"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..399
                     /locus_tag="ACL8JK_002076"
     CDS             <1..399
                     /locus_tag="ACL8JK_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGS1786873.1"
                     /translation="SEIIAYNLSTSPNLEQVQTMLEQSFTEKHYENTILHSDQGWQYQ
                     HDSYHQFLEGKGIQASISRKGNSPDNGMMESFFGILKSEMFYGYEKTFKSLNRLEQAI
                     VDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(578..>829)
                     /locus_tag="ACL8JK_002077"
     CDS             complement(578..>829)
                     /locus_tag="ACL8JK_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGS1786874.1"
                     /translation="VPAQPGTEDKKLSAPKPDMQPSPQPEGKKPSVPEINQEKEKAKL
                     AVATEKKLPSTGVASNLVLEIIGLLGLIGTSFIAMKRRK"
BASE COUNT          260 a          156 c          144 g          269 t
ORIGIN      
        1 agcgaaatta tcgcctataa tctttcaact tcacccaatt tagaacaagt acaaacaatg
       61 ttggaacagt cattcacaga gaagcactac gagaatacga ttctccatag tgaccaaggc
      121 tggcaatatc aacacgattc ttatcatcag tttcttgagg gtaagggaat tcaagcatcc
      181 atttcacgta agggtaacag cccagacaat ggtatgatgg agtccttttt tgggattctg
      241 aaatcggaaa tgttttatgg ctatgagaaa acatttaaat cacttaatcg attggaacaa
      301 gctattgtag actatattga ttactacaac aataaacgaa ttaaggtaaa actaaaagga
      361 cttagccctg tgcaatacag aactaaatcc ttcggataaa ttaattgtct aacttttgcg
      421 gttcactagc cttctctttt tatatcttag attcatctct atatgaaatg acttataatt
      481 attagatacc aattataagt aaaatctttg ggatcttcaa tggttaacca atcaaatgct
      541 aaatatcgaa agtggatatt tttaaaaaac tgaatcatta ttttcttctt ttcatcgcga
      601 tgaatgaagt tccaatcaaa ccaaggagac caatgatctc aagaactaga ttagacgcca
      661 ctcctgtaga tggcaatttc ttctctgttg ctacagcaag cttagctttt tctttctcct
      721 gattaatctc tggtacactt ggtttcttac cctctggttg agggcttggt tgcatatctg
      781 gttttggagc agatagcttt ttatcctcag taccgggttg tgccggtac
//
LOCUS       DBERXF010000085          692 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.85, whole genome shotgun sequence.
ACCESSION   DBERXF010000085 DBERXF010000000
VERSION     DBERXF010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.85"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(74..147)
                     /locus_tag="ACL8JK_002078"
     tRNA            complement(74..147)
                     /locus_tag="ACL8JK_002078"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="ACL8JK_002079"
     tRNA            complement(157..242)
                     /locus_tag="ACL8JK_002079"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="ACL8JK_002080"
     tRNA            complement(250..321)
                     /locus_tag="ACL8JK_002080"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="ACL8JK_002081"
     tRNA            complement(344..416)
                     /locus_tag="ACL8JK_002081"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="ACL8JK_002082"
     tRNA            complement(435..516)
                     /locus_tag="ACL8JK_002082"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="ACL8JK_002083"
     tRNA            complement(522..594)
                     /locus_tag="ACL8JK_002083"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="ACL8JK_002084"
     tRNA            complement(619..691)
                     /locus_tag="ACL8JK_002084"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          179 a          204 c          149 g          160 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt atcttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ct
//
LOCUS       DBERXF010000086          661 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.86, whole genome shotgun sequence.
ACCESSION   DBERXF010000086 DBERXF010000000
VERSION     DBERXF010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..661
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.86"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..>661)
                     /locus_tag="ACL8JK_002085"
     CDS             complement(<1..>661)
                     /locus_tag="ACL8JK_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="reverse transcriptase domain-containing protein"
                     /protein_id="HGS1786875.1"
                     /translation="RQLGIPTVMDRMIQQAIVQVISPICEPHFSDTSYGFRPNRSCEK
                     AIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNIIEDGDTESLIRKYLHSGV
                     IINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLRFVRYADDCVITVGSEAA
                     AKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFWKSSDGWKSRPHQDSVWR
                     FK"
BASE COUNT          185 a          151 c          116 g          209 t
ORIGIN      
        1 cttaaatctc caaacactat cttgatgtgg acgacttttc caaccatctg atgatttcca
       61 gaacccgaaa cctagatatt tcaactctct tggtctggta atcttagtct tggtcatgtt
      121 tactttcaga cctagccgtt tctcaataaa acgactgact gaatacatca cacgcttagc
      181 ggctgcctcg cttccgaccg taatcacaca atcgtctgcg tagcgaacaa atcgaagccc
      241 tctcttttct aattccttgt ccaattcatt aagcatgata ttggataaga gaggagataa
      301 atttcctccc tgtggcgtgc caactagcgt tttataacgt tgaccgttaa tgataacacc
      361 tgaatgaaga tatttacgaa tcaaggattc cgtatctccg tcttcgataa tgttatgtac
      421 taaggacatc aatctatctt gaggaactgt atcgaaaaat ttctctaggt ctatgtccac
      481 tatccactca tagccgtcat ttaagtactc taagagcttc atgatggctt tttcacatga
      541 cctatttggt ctgaatccat agctcgtatc tgagaaatgg ggttcacaaa tagggctaat
      601 aacttgaaca atggcctgtt gaatcattct atccataact gttggaattc ctagttgacg
      661 g
//
LOCUS       DBERXF010000087          610 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.87, whole genome shotgun sequence.
ACCESSION   DBERXF010000087 DBERXF010000000
VERSION     DBERXF010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..610
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.87"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>610
                     /gene="cbpA"
                     /locus_tag="ACL8JK_002086"
     CDS             <1..>610
                     /gene="cbpA"
                     /locus_tag="ACL8JK_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choline-binding protein CbpA"
                     /protein_id="HGS1786876.1"
                     /translation="KEEAKESRNEEKVKQAKAKVESKKAEATRLENIKTDRKKAEEAK
                     RRAAEEDKVKEKPAEQPQPAPAPQPEKPTEEPENPAPAPKPENPAEQPKAEKPADQQA
                     EEDYARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQ
                     NNGSWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQYNG"
BASE COUNT          255 a          132 c          130 g           93 t
ORIGIN      
        1 taaaagagga agctaaggaa tctcgaaacg aggaaaaagt taagcaagca aaagcgaaag
       61 ttgagagtaa aaaagctgag gctacaaggt tagaaaacat caagacagat cgtaaaaaag
      121 cagaagaagc taaacgaaga gcagcagaag aagataaagt taaagaaaaa ccagctgaac
      181 aaccacaacc agcgccggct cctcaaccag aaaaaccaac tgaagagcct gagaatccag
      241 ctccagctcc aaaacctgag aatccagctg aacaaccaaa agcagaaaaa ccagctgatc
      301 aacaagctga agaagactat gctcgtagat cagaagaaga atataatcgc ttgactcaac
      361 agcaaccgcc aaaaactgaa aaaccagcac aaccatctac tccaaaaaca ggctggaaac
      421 aagaaaacgg tatgtggtac ttctacaata ctgatggttc aatggcgaca ggatggctcc
      481 aaaacaatgg ctcatggtac tacctaaaca gcaatggcgc tatggcgaca ggatggctcc
      541 aaaacaatgg ttcatggtac tatctaaacg ctaatggttc aatggcaaca ggatggctcc
      601 aatacaatgg
//
LOCUS       DBERXF010000088          550 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.88, whole genome shotgun sequence.
ACCESSION   DBERXF010000088 DBERXF010000000
VERSION     DBERXF010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..550
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.88"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            80..550
                     /locus_tag="ACL8JK_002087"
                     /pseudo
     CDS             80..550
                     /locus_tag="ACL8JK_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          162 a          114 c          107 g          167 t
ORIGIN      
        1 gtaattttag aaatctgcct gagattatgt cttgggaggt tgaaacagtc cggggagtga
       61 ctgtttcaat cgggagatgg agatgagctt tattgcgcaa gattttaaca atctcaatat
      121 catcactgtt cttgaaggta gaacacaagc tgtcatccga gatcactttc ttaaatatga
      181 tagagccgtc cgatgtcgcg tcaaaatcat tactatggat atgtttagcc cttactatga
      241 cttagctaaa cagcttcgct ttcaaatttc taggctcagg ctgaaacagt ctcccaggct
      301 gtttcactcc cgaatgctaa aatcgttctt gatcgctttc acattgtaca acatcttagc
      361 cgtgctatga gtcgtgtgca tgtccaaatc atgaatcagt ttcatcgaaa atcccatgaa
      421 tacaaggcta tcaagcgtta ctggaaactc attcaacagg atagccgtaa actgagtgat
      481 aagcgatttt atcgccctac ttttcgcatg cacttaacaa ataaagaaat tcttgacaag
      541 attttaagct
//
LOCUS       DBERXF010000089          500 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 454006
            SAMN38106709-rid24758233.denovo.89, whole genome shotgun sequence.
ACCESSION   DBERXF010000089 DBERXF010000000
VERSION     DBERXF010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38106709
            Sequence Read Archive: SRR26673039
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570273.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570273.1
            Genome Coverage       :: 98x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 08:31:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,088
            CDSs (total)                      :: 2,055
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 80 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 52 of 146
            Pseudo Genes (multiple problems)  :: 44 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38106709-rid24758233.denovo.89"
                     /strain="GPSC46"
                     /isolate="454006"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..500
                     /locus_tag="ACL8JK_002088"
                     /pseudo
     CDS             1..500
                     /locus_tag="ACL8JK_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          142 a          110 c          106 g          142 t
ORIGIN      
        1 ttgaggcagg atttgataag ctgatagaaa ttaagcattg accgcttcta aaattcagga
       61 tatcctctca gtcgcacctc gttctatcgg aacaacatct cctgctcgtg aattcgaaat
      121 catcgaaatc atcaaacatt acaagagact cattgacaag gcggaaacat gtgtcaatga
      181 cttgatggct gagttcaact cggtcatcac gacggttact gggattggga atcgtttagg
      241 ggcggtcatt ttagccgaga ttcgaaatat tcatgccttt gataatcctg ctcaattaca
      301 agctttcgct ggactggatt cttctattta tcagtcaggt cagattgatt tagctggaag
      361 aatgatcaaa cggggttccc ctcatctgcg gtgggcactc atacaagctg ccaaagcatg
      421 cgctcgcttt tcacctgctt ttaaggccta tcttaagact aagttagaac aaggaaaaca
      481 ttacaatgta gccatcatcc
//
